Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "Secretome function" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Brain expression cluster" "Cell line expression cluster" "Single cell expression cluster" Interactions "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" ABCB4 "GBD1, MDR2, MDR3, PFIC-3, PGY3" ENSG00000005471 "ATP binding cassette subfamily B member 4" P21439 7 87401696-87480435 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "liver: 119.4" "Cell type enriched" "Detected in some" 10 "Hepatocytes: 202.2" "Cancer enriched" "Detected in some" 11 "liver cancer: 16.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "memory B-cell: 4.4;naive B-cell: 8.2" "Lineage enriched" "Detected in many" 7 "B-cells: 8.2" "Cancer enhanced" "Detected in some" "skin cancer: 9.0" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Skin - Fibroblast_1" "Low region specificity" "Detected in many" "HPA049395, HPA053288" Enhanced Approved "Nucleoplasm,Plasma membrane,Focal adhesion sites,Cytosol" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 43: Hepatocytes - Metabolism" "Nucleoplasm, Plasma membrane" "Focal adhesion sites, Cytosol" "HPA049395: AB_2680745, HPA053288: AB_2682102" "unprognostic (7.92e-2)" "unprognostic (8.87e-2)" "unprognostic (1.97e-1)" "unprognostic (1.90e-1)" "unprognostic (8.95e-2)" "unprognostic (1.06e-2)" "unprognostic (2.35e-3)" "unprognostic (9.91e-2)" "unprognostic (3.53e-1)" "unprognostic (1.19e-1)" "unprognostic (2.44e-3)" "unprognostic (8.43e-2)" "unprognostic (2.83e-2)" "unprognostic (8.01e-3)" "unprognostic (7.12e-2)" "unprognostic (2.11e-2)" "unprognostic (2.47e-1)" ABTB3 "ABTB2B, BTBD11, FLJ33957" ENSG00000151136 "Ankyrin repeat and BTB domain containing 3" A6QL63 12 107318421-107659642 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 28.5;parathyroid gland: 96.9" "Cell type enriched" "Detected in many" 5 "Inhibitory neurons: 257.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 3.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Pancreas - Alpha cells, Skin - Keratinocyte (other), Testis - Peritubular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055898, HPA061334" Supported Nucleoplasm,Cytosol NA NA "Cluster 11: T-cells - Unknown function" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 49: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 8: Neurons - Neuronal signaling" Nucleoplasm Cytosol "HPA055898: AB_2682964, HPA061334: " "unprognostic (3.40e-2)" "unprognostic (4.06e-1)" "unprognostic (2.37e-1)" "unprognostic (7.85e-2)" "unprognostic (8.78e-3)" "unprognostic (4.82e-2)" "unprognostic (3.52e-1)" "unprognostic (2.12e-1)" "unprognostic (1.52e-1)" "unprognostic (5.92e-2)" "unprognostic (5.33e-2)" "unprognostic (1.78e-1)" "unprognostic (4.92e-8)" "unprognostic (2.66e-1)" "unprognostic (1.55e-1)" "unprognostic (3.33e-2)" "unprognostic (9.07e-3)" ACAT2 ENSG00000120437 "Acetyl-CoA acetyltransferase 2" Q9BWD1 6 159762045-159779112 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 224.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 206.8;Basal respiratory cells: 265.8;Hepatocytes: 225.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021106, HPA025736, HPA025765, HPA025811" Enhanced Approved Nucleoplasm,Cytosol NA NA 14000000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 83: Liver - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 62: Hepatocytes - Metabolism" 3 Cytosol Nucleoplasm "CAB021106: AB_10058215, HPA025736: AB_1844487, HPA025765: AB_1844485, HPA025811: AB_1844488" "unprognostic (3.31e-1)" "unprognostic (2.44e-2)" "prognostic favorable (1.12e-4)" "prognostic unfavorable (7.25e-4)" "unprognostic (1.38e-1)" "unprognostic (2.03e-1)" "unprognostic (9.25e-2)" "unprognostic (4.76e-2)" "unprognostic (1.43e-1)" "unprognostic (2.58e-1)" "unprognostic (1.21e-1)" "unprognostic (1.59e-1)" "prognostic unfavorable (7.38e-4)" "unprognostic (1.39e-1)" "unprognostic (1.50e-2)" "unprognostic (8.56e-2)" "unprognostic (2.54e-2)" ACD "Pip1, Ptop, Tint1, Tpp1" ENSG00000102977 "ACD shelterin complex subunit and telomerase recruitment factor" Q96AP0 16 67657512-67660810 "Disease related genes, Human disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant, Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 62.0;Late spermatids: 67.2;Oocytes: 64.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049411, HPA057660" Approved Enhanced "Nuclear bodies" NA Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 66: Non-specific - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" 25 "Nuclear bodies" "HPA049411: AB_2680752, HPA057660: AB_2683493" "unprognostic (1.47e-1)" "unprognostic (3.77e-2)" "unprognostic (1.09e-2)" "unprognostic (7.15e-3)" "unprognostic (2.22e-1)" "unprognostic (4.24e-3)" "prognostic unfavorable (2.42e-6)" "unprognostic (1.50e-2)" "unprognostic (4.75e-2)" "unprognostic (2.02e-1)" "unprognostic (1.13e-3)" "unprognostic (3.27e-2)" "unprognostic (8.88e-2)" "unprognostic (6.34e-2)" "unprognostic (2.00e-1)" "unprognostic (1.18e-1)" "unprognostic (3.30e-1)" ACTC1 "ACTC, CMD1R" ENSG00000159251 "Actin alpha cardiac muscle 1" P68032 15 34790230-34795549 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Muscle protein" "Atrial septal defect, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 21 "heart muscle: 11007.3" "Group enriched" "Detected in some" 14 "Cardiomyocytes: 1835.2;Skeletal myocytes: 843.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 20.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 9 "Sarcoma: 254.4" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Skin - Smooth muscle cells, Thyroid - Smooth muscle cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB037330, HPA041264, HPA041271" Enhanced NA NA 2400000000 "Cluster 30: Heart muscle - Heart development" "Cluster 49: Hindbrain - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 68: Cardiomyocytes - Muscle contraction" 1 "CAB037330: , HPA041264: AB_2677383, HPA041271: AB_2677386" "unprognostic (8.18e-3)" "unprognostic (3.74e-2)" "unprognostic (4.82e-3)" "unprognostic (1.19e-2)" "unprognostic (3.04e-2)" "prognostic unfavorable (3.72e-5)" "unprognostic (3.26e-1)" "unprognostic (2.05e-3)" "unprognostic (2.26e-1)" "unprognostic (7.98e-2)" "unprognostic (1.14e-2)" "unprognostic (2.10e-3)" "unprognostic (5.68e-4)" "unprognostic (8.79e-2)" "unprognostic (1.65e-1)" "unprognostic (1.48e-2)" "prognostic unfavorable (9.32e-4)" ADAM33 "C20orf153, dJ964F7.1, DKFZp434K0521" ENSG00000149451 "ADAM metallopeptidase domain 33" Q9BZ11 20 3667965-3682246 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" Asthma "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 72.6" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 34.3;Fibroblasts: 39.2;Leydig cells: 21.9;Mesothelial cells: 14.6;Microglial cells: 17.9;Smooth muscle cells: 21.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "testis cancer: 12.9" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Liver - Hepatic stellate cells, Thyroid - Fibroblasts" "Region enhanced" "Detected in single" "cerebral cortex: 1.0" "Low region specificity" "Detected in all" "HPA067152, HPA071758" Approved Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 49: Hindbrain - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear speckles" "HPA067152: AB_2685791, HPA071758: " "unprognostic (1.10e-1)" "unprognostic (3.02e-2)" "unprognostic (2.24e-2)" "unprognostic (3.35e-3)" "unprognostic (4.39e-3)" "unprognostic (7.43e-4)" "unprognostic (7.14e-3)" "unprognostic (1.67e-1)" "unprognostic (1.78e-3)" "unprognostic (1.28e-1)" "unprognostic (1.26e-1)" "unprognostic (3.56e-1)" "unprognostic (2.75e-11)" "unprognostic (1.05e-2)" "unprognostic (1.92e-1)" "unprognostic (3.21e-5)" "unprognostic (3.10e-3)" ADAMTS2 "ADAM-TS2, ADAMTS-3, hPCPNI, NPI, PCINP" ENSG00000087116 "ADAM metallopeptidase with thrombospondin type 1 motif 2" O95450 5 179110853-179345461 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 29.6;Fibroblasts: 35.1;Kupffer cells: 74.2;Macrophages: 19.6;Mesothelial cells: 22.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA028363, HPA028444" Uncertain Approved "Vesicles,Plasma membrane" "Secreted to extracellular matrix" Enzyme NA NA 2000000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 58: Macrophages - Innate immune response" "Plasma membrane" Vesicles "HPA028363: , HPA028444: AB_10601964" "unprognostic (6.78e-2)" "unprognostic (7.83e-2)" "unprognostic (1.13e-1)" "unprognostic (5.50e-2)" "unprognostic (8.85e-3)" "unprognostic (4.80e-2)" "unprognostic (1.09e-1)" "unprognostic (2.22e-2)" "unprognostic (1.58e-1)" "unprognostic (1.91e-2)" "unprognostic (2.08e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.71e-8)" "unprognostic (1.32e-3)" "unprognostic (1.03e-2)" "unprognostic (7.16e-3)" "unprognostic (1.48e-2)" ADAMTS20 GON-1 ENSG00000173157 "ADAM metallopeptidase with thrombospondin type 1 motif 20" P59510 12 43353866-43552203 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bipolar cells: 4.6;Inhibitory neurons: 15.4;Oligodendrocyte precursor cells: 10.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "medulla oblongata: 3.6;pons: 6.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 9.4" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027608, HPA027609" Uncertain "Secreted to extracellular matrix" Enzyme NA NA "Cluster 49: Hindbrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 65: Neurons - Synaptic function" "HPA027608: AB_10600098, HPA027609: AB_10599024" "unprognostic (3.18e-2)" "unprognostic (1.19e-1)" "unprognostic (1.91e-2)" "unprognostic (2.04e-1)" "unprognostic (9.61e-2)" "unprognostic (3.29e-1)" "unprognostic (6.67e-2)" "unprognostic (2.26e-1)" "unprognostic (1.05e-4)" "unprognostic (7.42e-2)" "unprognostic (2.02e-1)" "unprognostic (9.81e-3)" "unprognostic (2.57e-1)" ADAMTSL2 KIAA0605 ENSG00000197859 "ADAMTS like 2" Q86TH1 9 133532164-133575519 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 70.8;liver: 35.0" "Cell type enhanced" "Detected in many" "Distal tubular cells: 9.2;Fibroblasts: 9.2;Microglial cells: 11.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 4.5" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA045634, HPA053812" Approved Approved Vesicles "Secreted in other tissues" "No annotated function" NA NA 170000000 "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 49: Hindbrain - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 53: Fibroblasts - ECM organization" Vesicles "HPA045634: AB_2679399, HPA053812: AB_2682271" "unprognostic (5.10e-2)" "unprognostic (1.50e-2)" "prognostic unfavorable (5.01e-4)" "unprognostic (8.35e-2)" "unprognostic (1.07e-1)" "unprognostic (5.50e-2)" "unprognostic (6.78e-3)" "unprognostic (1.31e-2)" "unprognostic (5.49e-2)" "unprognostic (1.35e-1)" "prognostic favorable (6.70e-4)" "unprognostic (5.17e-2)" "unprognostic (7.37e-2)" "unprognostic (1.56e-1)" "unprognostic (3.40e-1)" "unprognostic (1.65e-1)" "unprognostic (2.42e-1)" ADORA1 RDC7 ENSG00000163485 "Adenosine A1 receptor" P30542 1 203090654-203167405 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 44.2;testis: 20.9" "Cell type enhanced" "Detected in some" "Ductal cells: 12.9;Excitatory neurons: 17.5;Muller glia cells: 40.9;Oligodendrocyte precursor cells: 33.0;Oligodendrocytes: 29.3" "Cancer enhanced" "Detected in many" "glioma: 24.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 51.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Heart muscle - Cardiomyocytes, Kidney - Podocytes, Skin - Eccrine sweat gland cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044383 Supported "Plasma membrane" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 49: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 10: Muller glia cells - Visual perception" 5 "Plasma membrane" "HPA044383: AB_2678921" "unprognostic (3.93e-3)" "unprognostic (8.16e-2)" "unprognostic (6.16e-2)" "unprognostic (2.38e-3)" "unprognostic (2.25e-2)" "unprognostic (2.34e-1)" "unprognostic (4.64e-2)" "unprognostic (4.17e-2)" "unprognostic (3.04e-1)" "unprognostic (4.80e-3)" "unprognostic (1.42e-1)" "unprognostic (2.98e-1)" "unprognostic (2.96e-3)" "unprognostic (1.54e-1)" "unprognostic (1.27e-1)" "unprognostic (4.13e-2)" "unprognostic (5.76e-4)" AKR1B1 "ALDR1, AR" ENSG00000085662 "Aldo-keto reductase family 1 member B" P15121 7 134442356-134459284 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "adrenal gland: 2944.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 1220.3;Collecting duct cells: 657.4;Cytotrophoblasts: 1189.2;Extravillous trophoblasts: 1344.0;Syncytiotrophoblasts: 2081.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney cancer: 1445.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026425, CAB027391, CAB047353, HPA052751" Enhanced Supported Nucleoplasm,Cytosol No No 1500000 "Cluster 39: T-cells - T-cell receptor" "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 3: Basal prostatic cells - Lipid metabolism" 2 Cytosol Nucleoplasm "CAB027391: , CAB047353: , HPA026425: AB_10601563, HPA052751: AB_2681935" "unprognostic (2.76e-2)" "unprognostic (2.84e-2)" "unprognostic (2.02e-2)" "unprognostic (1.37e-2)" "unprognostic (6.81e-2)" "unprognostic (2.26e-1)" "unprognostic (4.18e-2)" "unprognostic (5.09e-2)" "unprognostic (2.51e-3)" "unprognostic (2.47e-1)" "unprognostic (2.98e-2)" "unprognostic (8.78e-2)" "unprognostic (2.81e-2)" "prognostic unfavorable (2.44e-5)" "unprognostic (2.03e-1)" "unprognostic (1.39e-1)" "prognostic unfavorable (7.00e-4)" AKR1C1 "DD1, DDH, DDH1, HAKRC, MBAB" ENSG00000187134 "Aldo-keto reductase family 1 member C1" Q04828 10 4963253-4983283 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 603.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 231.2;Basal squamous epithelial cells: 350.6;Cholangiocytes: 228.9;Exocrine glandular cells: 301.6;Hepatocytes: 753.9" "Cancer enhanced" "Detected in many" "liver cancer: 64.2;lung cancer: 53.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.5" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Esophageal cancer: 532.2;Gallbladder cancer: 872.6;liver cancer: 767.2" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "CAB047303, HPA068265" Enhanced Enhanced "Endoplasmic reticulum,Cytosol" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" 2 "Endoplasmic reticulum, Cytosol" "CAB047303: , HPA068265: AB_2685966" "unprognostic (1.54e-2)" "prognostic favorable (3.05e-4)" "unprognostic (4.04e-2)" "unprognostic (8.38e-2)" "unprognostic (3.18e-2)" "unprognostic (7.05e-2)" "prognostic unfavorable (1.56e-4)" "unprognostic (1.70e-1)" "unprognostic (1.63e-1)" "unprognostic (8.38e-2)" "unprognostic (4.65e-1)" "unprognostic (1.82e-2)" "prognostic favorable (8.03e-9)" "unprognostic (1.19e-1)" "unprognostic (1.22e-1)" "unprognostic (5.72e-2)" "unprognostic (6.30e-2)" ALKAL1 "AUGB, FAM150A, UNQ9433" ENSG00000196711 "ALK and LTK ligand 1" Q6UXT8 8 52534037-52565430 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 2.3;thyroid gland: 2.3;urinary bladder: 1.5" "Cell type enhanced" "Detected in some" "Cholangiocytes: 13.4;Distal tubular cells: 3.1;Mucus glandular cells: 3.4;Oocytes: 5.1;Paneth cells: 3.0;Salivary duct cells: 3.7;Secretory cells: 2.8" "Cancer enhanced" "Detected in many" "thyroid cancer: 2.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lung cancer: 2.0" "Liver - Cholangiocyte, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA027368 Uncertain "Secreted to blood" Cytokine NA NA "Cluster 45: Intestine - Digestion" "Cluster 49: Hindbrain - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 17: Breast glandular cells - Lactation" 2 "HPA027368: AB_10602317" "unprognostic (1.18e-1)" "unprognostic (1.13e-4)" "unprognostic (9.47e-2)" "unprognostic (9.64e-2)" "unprognostic (1.52e-1)" "unprognostic (6.60e-2)" "unprognostic (1.70e-4)" "unprognostic (4.48e-2)" "unprognostic (1.71e-1)" "unprognostic (1.34e-1)" "unprognostic (9.58e-3)" ALX3 FND ENSG00000156150 "ALX homeobox 3" O95076 1 110059870-110070672 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 7.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.5;Cone photoreceptor cells: 1.7;Horizontal cells: 1.9;Mesothelial cells: 1.4;Oocytes: 2.9;Rod photoreceptor cells: 4.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 8 "olfactory bulb: 16.7" "Low region specificity" "Detected in single" HPA074290 Approved "Nucleoli fibrillar center" NA NA "Cluster 13: Skin - Cornification" "Cluster 49: Hindbrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "Nucleoli fibrillar center" "HPA074290: " "unprognostic (4.28e-1)" "unprognostic (4.41e-2)" "unprognostic (2.91e-1)" "unprognostic (2.48e-2)" "unprognostic (1.31e-1)" ANGPT2 Ang2 ENSG00000091879 "Angiopoietin 2" O15123 8 6499632-6563409 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Lymphatic endothelial cells: 498.2" "Cancer enhanced" "Detected in all" "renal cancer: 12.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.6" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "ovarian cancer: 10.4" "Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB011437, CAB017626" Approved "Secreted to blood" "Developmental protein" NA NA 3780000 110000 "Cluster 34: B-cells - Unknown function" "Cluster 34: Non-specific - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" 1 "CAB011437: , CAB017626: AB_1118956" "unprognostic (1.28e-1)" "prognostic unfavorable (7.99e-5)" "unprognostic (1.93e-2)" "unprognostic (1.23e-1)" "unprognostic (4.85e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (6.36e-5)" "unprognostic (1.66e-3)" "prognostic unfavorable (4.48e-4)" "unprognostic (2.94e-3)" "unprognostic (6.19e-3)" "unprognostic (1.38e-1)" "prognostic unfavorable (1.52e-7)" "prognostic unfavorable (3.87e-4)" "unprognostic (1.12e-1)" "unprognostic (1.46e-2)" "unprognostic (6.44e-2)" ANKRD36C DKFZp667P0924 ENSG00000174501 "Ankyrin repeat domain 36C" Q5JPF3 2 95836919-95991831 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.6" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 1117.6;Gastric mucus-secreting cells: 479.9;Mucus glandular cells: 1064.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA051757, HPA057661" Approved Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 40: Non-specific - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 45: Non-specific - Mixed function" "Nucleoplasm, Cytosol" "HPA051757: AB_2681594, HPA057661: AB_2683494" "unprognostic (2.21e-1)" "unprognostic (5.39e-2)" "unprognostic (6.32e-2)" "unprognostic (2.50e-1)" "unprognostic (1.83e-1)" "unprognostic (3.79e-3)" "unprognostic (1.29e-1)" "unprognostic (5.57e-2)" "unprognostic (1.57e-1)" "unprognostic (2.03e-1)" "unprognostic (1.44e-2)" "unprognostic (5.29e-3)" "unprognostic (5.35e-6)" "unprognostic (9.99e-2)" "unprognostic (2.47e-1)" "unprognostic (3.44e-2)" "unprognostic (1.79e-1)" ANKS6 "ANKRD14, FLJ36928, NPHP16, SAMD6" ENSG00000165138 "Ankyrin repeat and sterile alpha motif domain containing 6" Q68DC2 9 98731329-98796965 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Joubert syndrome, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 26.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 31.7;Excitatory neurons: 51.1;Inhibitory neurons: 46.6;Oligodendrocytes: 50.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA008355 Approved Uncertain Nucleoli,Cytosol NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 49: Hindbrain - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 51: Oligodendrocytes - Unknown function" 23 Nucleoli Cytosol "HPA008355: AB_2058277" "unprognostic (1.66e-1)" "unprognostic (1.46e-1)" "unprognostic (9.31e-2)" "unprognostic (9.15e-3)" "unprognostic (6.90e-3)" "unprognostic (1.22e-1)" "unprognostic (4.29e-3)" "unprognostic (4.10e-2)" "unprognostic (1.48e-1)" "unprognostic (3.46e-3)" "unprognostic (1.00e-1)" "unprognostic (5.94e-2)" "prognostic favorable (3.44e-5)" "unprognostic (1.40e-1)" "unprognostic (1.02e-1)" "unprognostic (3.95e-2)" "unprognostic (2.68e-1)" ANXA3 ANX3 ENSG00000138772 "Annexin A3" P12429 4 78551747-78610451 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Phospholipase A2 inhibitor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 334.1" "Cell type enhanced" "Detected in many" "Adipocytes: 273.2;Alveolar cells type 1: 599.3;Ductal cells: 343.6;Pancreatic endocrine cells: 353.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 328 "neutrophil: 208.7" "Lineage enriched" "Detected in single" 328 "granulocytes: 208.7" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 1, Pancreas - Ductal cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "HPA013398, HPA013431" Enhanced Supported "Plasma membrane" NA NA 6400000 "Cluster 4: Neutrophils - Degranulation" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" "Plasma membrane" "HPA013398: AB_1844861, HPA013431: AB_1844862" "unprognostic (2.66e-1)" "unprognostic (5.65e-3)" "unprognostic (4.92e-3)" "unprognostic (8.67e-2)" "unprognostic (2.41e-1)" "unprognostic (5.02e-3)" "unprognostic (4.17e-2)" "unprognostic (1.87e-1)" "unprognostic (5.09e-2)" "unprognostic (2.10e-3)" "prognostic unfavorable (1.28e-4)" "unprognostic (4.82e-2)" "prognostic favorable (8.48e-6)" "unprognostic (2.23e-1)" "unprognostic (2.02e-2)" "unprognostic (7.20e-2)" "unprognostic (3.30e-2)" AP1S2 "MRX59, MRXS5, PGS, SIGMA1B" ENSG00000182287 "Adaptor related protein complex 1 subunit sigma 2" P56377 X 15825806-15854931 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "epididymis: 642.6" "Cell type enhanced" "Detected in all" "Hofbauer cells: 428.3;Kupffer cells: 344.9;Langerhans cells: 713.8;Macrophages: 299.1;monocytes: 383.3;Schwann cells: 365.0" "Group enriched" "Detected in all" 4 "endometrial cancer: 13.1;glioma: 22.0;melanoma: 49.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 326.1;intermediate monocyte: 324.4;myeloid DC: 220.8;non-classical monocyte: 175.6;plasmacytoid DC: 81.9" "Group enriched" "Detected in all" 5 "dendritic cells: 220.8;monocytes: 326.1" "Cancer enhanced" "Detected in all" "skin cancer: 184.4" "Breast - Endothelial cells, Kidney - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049894, HPA060945" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 49: Hindbrain - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 29: Monocytes - Innate immune response" 2 "Golgi apparatus, Vesicles" "HPA049894: AB_2680939, HPA060945: AB_2684393" "prognostic favorable (9.86e-4)" "unprognostic (4.62e-2)" "unprognostic (2.11e-1)" "unprognostic (1.68e-1)" "unprognostic (2.47e-3)" "unprognostic (3.85e-1)" "unprognostic (2.03e-3)" "unprognostic (5.76e-2)" "unprognostic (1.43e-2)" "prognostic favorable (5.53e-6)" "unprognostic (1.85e-2)" "unprognostic (5.61e-2)" "unprognostic (5.08e-2)" "unprognostic (6.35e-2)" "unprognostic (3.13e-1)" "unprognostic (9.34e-2)" "unprognostic (6.47e-2)" AQP3 GIL ENSG00000165272 "Aquaporin 3 (Gill blood group)" Q92482 9 33441156-33447596 "Blood group antigen proteins, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" Transport "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 1483.2;skin 1: 563.9;urinary bladder: 662.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1556.2;Basal squamous epithelial cells: 1011.0;Collecting duct cells: 1073.6;Squamous epithelial cells: 2365.1;Suprabasal keratinocytes: 2153.4" "Group enriched" "Detected in all" 5 "cervical cancer: 319.0;head and neck cancer: 283.7;lung cancer: 146.8;urothelial cancer: 221.3" "Region enhanced" "Detected in all" "pons: 47.2" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 182.0;T-reg: 205.9" "Lineage enriched" "Detected in many" 18 "T-cells: 205.9" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 403.6" "Lung - Alveolar cells type 2, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA014924 Enhanced Supported "Plasma membrane" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 23 "Plasma membrane" "HPA014924: AB_2669120" "unprognostic (4.29e-2)" "prognostic favorable (5.31e-4)" "unprognostic (1.15e-1)" "unprognostic (3.26e-2)" "unprognostic (1.84e-2)" "unprognostic (1.11e-2)" "unprognostic (9.95e-2)" "unprognostic (1.64e-1)" "unprognostic (3.46e-1)" "unprognostic (9.06e-2)" "unprognostic (4.87e-2)" "unprognostic (1.25e-1)" "unprognostic (1.54e-2)" "unprognostic (1.16e-2)" "unprognostic (2.59e-1)" "unprognostic (3.73e-2)" "unprognostic (4.51e-2)" AQP7 "AQP7L, AQP9, AQPap" ENSG00000165269 "Aquaporin 7" O14520 9 33383179-33402682 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 205.9;breast: 101.5;heart muscle: 105.1" "Cell type enhanced" "Detected in many" "Adipocytes: 105.7;Cardiomyocytes: 87.0;Early spermatids: 152.5;Proximal enterocytes: 143.0;Proximal tubular cells: 53.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 22: Proximal enterocytes - Digestion" 1 "unprognostic (3.25e-2)" "unprognostic (3.81e-3)" "unprognostic (1.25e-5)" "unprognostic (7.22e-3)" "unprognostic (1.50e-1)" "unprognostic (3.32e-1)" "unprognostic (4.67e-2)" "unprognostic (3.06e-2)" "unprognostic (9.99e-2)" "unprognostic (4.65e-2)" "unprognostic (8.56e-4)" "unprognostic (1.21e-1)" "prognostic favorable (9.21e-8)" "unprognostic (2.42e-1)" "unprognostic (1.28e-1)" "unprognostic (1.61e-1)" "unprognostic (2.12e-3)" ARHGAP24 "DKFZP564B1162, FilGAP, FLJ33877" ENSG00000138639 "Rho GTPase activating protein 24" Q8N264 4 85475150-86002668 "Predicted intracellular proteins" "Angiogenesis, Differentiation" "Developmental protein, GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 96.3" "Group enriched" "Detected in many" 4 "Astrocytes: 1294.0;Microglial cells: 864.2" "Cancer enhanced" "Detected in all" "renal cancer: 9.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 16.0;memory B-cell: 47.4;naive B-cell: 36.9;plasmacytoid DC: 12.7" "Group enriched" "Detected in many" 5 "B-cells: 47.4;dendritic cells: 12.7;monocytes: 16.0" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014288 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 52: Kidney - Transmembrane transport" "Cluster 49: Hindbrain - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 47: Astrocytes - Unknown function" 1 "Plasma membrane, Cytosol" "HPA014288: AB_1844994" "unprognostic (2.19e-1)" "unprognostic (1.30e-1)" "unprognostic (1.14e-1)" "unprognostic (2.95e-2)" "unprognostic (2.81e-1)" "unprognostic (9.22e-2)" "unprognostic (5.75e-3)" "unprognostic (4.28e-3)" "unprognostic (3.66e-1)" "unprognostic (1.33e-1)" "unprognostic (5.91e-2)" "unprognostic (6.45e-2)" "prognostic favorable (1.67e-11)" "unprognostic (1.75e-2)" "unprognostic (6.86e-2)" "unprognostic (2.50e-2)" "unprognostic (8.75e-4)" ARHGEF16 "GEF16, NBR" ENSG00000130762 "Rho guanine nucleotide exchange factor 16" Q5VV41 1 3454665-3481113 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 42.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 75.4;Extravillous trophoblasts: 65.7;Gastric mucus-secreting cells: 56.6;Intestinal goblet cells: 57.1;Paneth cells: 48.6;Proximal enterocytes: 64.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells" "Region enhanced" "Detected in many" "olfactory bulb: 4.7" "Low region specificity" "Detected in many" HPA010609 Approved NA NA "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 5: Enterocytes - Absorption" 8 "HPA010609: AB_1845004" "unprognostic (1.28e-1)" "unprognostic (1.92e-1)" "unprognostic (1.71e-1)" "unprognostic (1.83e-2)" "unprognostic (4.31e-1)" "unprognostic (2.09e-2)" "prognostic unfavorable (1.82e-4)" "unprognostic (2.65e-1)" "unprognostic (5.59e-2)" "unprognostic (1.79e-2)" "unprognostic (5.39e-2)" "unprognostic (9.16e-2)" "prognostic favorable (1.24e-10)" "unprognostic (6.46e-2)" "unprognostic (2.86e-1)" "unprognostic (1.71e-2)" "unprognostic (3.29e-2)" ARMC5 FLJ13063 ENSG00000140691 "Armadillo repeat containing 5" Q96C12 16 31458080-31467166 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cushing syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041524, HPA063706" Approved Approved "Nucleoplasm,Focal adhesion sites,Cytosol" "Intracellular and membrane" "No annotated function" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 56: Non-specific - Unknown function" "Cluster 49: Hindbrain - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 80: Non-specific - Transcription" 8 "Nucleoplasm, Cytosol" "Focal adhesion sites" "HPA041524: AB_10796676, HPA063706: AB_2685098" "unprognostic (1.37e-1)" "unprognostic (1.68e-3)" "unprognostic (8.22e-3)" "unprognostic (9.96e-2)" "unprognostic (2.59e-1)" "unprognostic (2.94e-3)" "unprognostic (4.09e-2)" "unprognostic (6.14e-3)" "unprognostic (2.37e-1)" "unprognostic (1.11e-1)" "prognostic favorable (1.97e-6)" "unprognostic (4.70e-2)" "unprognostic (3.60e-2)" "unprognostic (1.99e-2)" "unprognostic (2.34e-2)" "unprognostic (1.57e-1)" "unprognostic (1.45e-1)" ARTN "ENOVIN, EVN, NBN" ENSG00000117407 Artemin Q5T4W7 1 43933320-43937240 "Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Club cells: 4.3;Early spermatids: 10.1;Granulosa cells: 8.3;Ionocytes: 4.4;Rod photoreceptor cells: 5.3;Smooth muscle cells: 5.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Esophageal cancer: 47.6;head and neck cancer: 57.7" "Region enriched" "Detected in single" 9 "olfactory bulb: 3.3" "Region enriched" "Detected in single" 5 "olfactory bulb: 3.5" "Secreted in other tissues" "Growth factor" NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 48: Smooth muscle cells - Signal transduction" 1 "unprognostic (1.98e-1)" "unprognostic (1.25e-1)" "unprognostic (3.60e-2)" "unprognostic (1.86e-1)" "unprognostic (1.55e-1)" "unprognostic (1.01e-1)" "unprognostic (3.07e-3)" "unprognostic (1.18e-1)" "unprognostic (3.08e-1)" "prognostic favorable (8.18e-4)" "unprognostic (2.34e-1)" "unprognostic (1.70e-1)" "unprognostic (9.59e-6)" "unprognostic (2.35e-2)" "unprognostic (3.04e-2)" "unprognostic (1.48e-3)" "unprognostic (1.53e-1)" BARHL1 ENSG00000125492 "BarH like homeobox 1" Q9BZE3 9 132582606-132590252 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 295 "brain: 29.5" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "pons: 72.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "cerebellum: 3.2;midbrain: 2.4;pons and medulla: 1.1" "Region enhanced" "Detected in many" "cerebellum: 8.6" HPA004809 Enhanced NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 49: Hindbrain - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 11: Late spermatids - Unknown function" "HPA004809: AB_1078266" "unprognostic (2.29e-1)" "unprognostic (6.42e-2)" "unprognostic (8.07e-2)" "unprognostic (9.31e-2)" BCS1L "BCS, BJS, h-BCS, Hs.6719" ENSG00000074582 "BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone" Q9Y276 2 218658764-218663443 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Chaperone "Deafness, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037700, HPA037701" Supported NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 49: Hindbrain - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 39: Non-specific - Basic cellular processes" "HPA037700: AB_10794619, HPA037701: AB_10805235" "unprognostic (1.19e-1)" "unprognostic (1.41e-1)" "unprognostic (6.28e-2)" "unprognostic (4.99e-2)" "unprognostic (6.44e-2)" "unprognostic (4.31e-1)" "unprognostic (4.25e-2)" "unprognostic (2.45e-1)" "unprognostic (8.38e-2)" "unprognostic (1.83e-2)" "unprognostic (1.21e-2)" "unprognostic (6.02e-2)" "unprognostic (3.47e-3)" "unprognostic (1.59e-1)" "unprognostic (3.15e-2)" "unprognostic (8.38e-2)" "prognostic favorable (3.31e-4)" BDKRB2 BK-2 ENSG00000168398 "Bradykinin receptor B2" P30411 14 96204679-96244166 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 39.6" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 16.0;Endothelial cells: 16.7;Fibroblasts: 17.0;Ionocytes: 16.2;Langerhans cells: 19.0;Squamous epithelial cells: 15.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 18.2" "Kidney - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA003551, HPA050841" Approved Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 49: Hindbrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "Plasma membrane" "Golgi apparatus, Vesicles" "HPA003551: , HPA050841: AB_2681254" "unprognostic (1.03e-1)" "unprognostic (7.90e-2)" "unprognostic (1.12e-1)" "unprognostic (1.83e-1)" "unprognostic (8.79e-3)" "unprognostic (2.68e-2)" "unprognostic (1.93e-1)" "unprognostic (4.66e-2)" "unprognostic (1.94e-1)" "unprognostic (2.84e-2)" "unprognostic (3.19e-1)" "unprognostic (1.72e-1)" "unprognostic (3.32e-3)" "unprognostic (3.11e-2)" "unprognostic (9.40e-2)" "unprognostic (9.90e-2)" "unprognostic (1.49e-2)" BLACAT1 "linc-UBC1, LINC00912, onco-lncRNA-30" ENSG00000281406 "BLACAT1 overlapping LEMD1 locus" 1 205434885-205457091 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "epididymis: 3.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 6.1;Collecting duct cells: 9.7;Granulosa cells: 4.0;Horizontal cells: 3.8;Mucus glandular cells: 3.1;Salivary duct cells: 2.5;Sertoli cells: 2.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Prostate - Urothelial cells, Testis - Sertoli cells" NA NA "Cluster 49: Hindbrain - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 45: Non-specific - Mixed function" "unprognostic (3.01e-2)" "unprognostic (7.43e-2)" "unprognostic (1.69e-1)" "unprognostic (2.87e-3)" "unprognostic (5.22e-2)" "unprognostic (7.97e-2)" "unprognostic (5.59e-2)" "unprognostic (5.02e-2)" "unprognostic (2.13e-2)" "unprognostic (7.37e-3)" "unprognostic (5.36e-2)" "unprognostic (6.23e-7)" "unprognostic (3.09e-2)" "unprognostic (6.78e-2)" "unprognostic (1.84e-2)" "unprognostic (4.59e-1)" BLTP2 "BCOX, BCOX1, CT101, DKFZp686M0843, FMP27, Hob, KIAA0100, MGC111488" ENSG00000007202 "Bridge-like lipid transfer protein family member 2" Q14667 17 28614446-28645454 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042781 Uncertain Approved "Nuclear speckles,Cytosol" "Intracellular and membrane" "No annotated function" No No "Cluster 13: Non-specific - Mitochondria" "Cluster 35: Non-specific - Mitochondria" "Cluster 49: Hindbrain - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 33: Non-specific - DNA binding" "Nuclear speckles, Cytosol" "HPA042781: AB_10797020" "unprognostic (1.91e-1)" "unprognostic (1.03e-2)" "unprognostic (3.47e-2)" "unprognostic (5.26e-3)" "unprognostic (2.43e-1)" "unprognostic (6.89e-2)" "prognostic unfavorable (3.47e-5)" "unprognostic (4.99e-2)" "unprognostic (3.04e-1)" "unprognostic (3.03e-3)" "unprognostic (2.40e-2)" "unprognostic (2.53e-1)" "unprognostic (4.24e-3)" "unprognostic (7.58e-2)" "unprognostic (5.84e-2)" "unprognostic (1.22e-1)" "unprognostic (6.67e-2)" BLVRB "FLR, SDR43U1" ENSG00000090013 "Biliverdin reductase B" P30043 19 40447765-40465764 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 615.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 2110.5;Hepatocytes: 827.2;Hofbauer cells: 1099.8;Proximal enterocytes: 929.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 466.2" "Group enriched" "Detected in all" 7 "dendritic cells: 343.8;monocytes: 466.2" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041698, HPA041937" Enhanced Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" No No 370000000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 40: Non-specific - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 1: Erythroid cells - Oxygen transport" 1 Cytosol "Nucleoplasm, Vesicles, Plasma membrane" "HPA041698: AB_10796781, HPA041937: AB_10794308" "unprognostic (1.86e-1)" "unprognostic (1.14e-2)" "unprognostic (4.23e-1)" "unprognostic (1.50e-1)" "unprognostic (2.08e-1)" "unprognostic (2.46e-1)" "unprognostic (9.92e-2)" "unprognostic (1.20e-2)" "unprognostic (8.56e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (3.90e-4)" "unprognostic (2.30e-1)" "unprognostic (2.70e-1)" "unprognostic (2.02e-1)" "unprognostic (5.11e-2)" "unprognostic (1.25e-1)" "unprognostic (3.92e-2)" BMP2 BMP2A ENSG00000125845 "Bone morphogenetic protein 2" P12643 20 6767686-6780246 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 157.9;Alveolar cells type 2: 127.0;Basal keratinocytes: 109.2;Distal enterocytes: 80.0;Lymphatic endothelial cells: 116.5;Suprabasal keratinocytes: 71.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 30.7" "Pancreas - Ductal cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA058610, CAB078457" Enhanced Vesicles "Secreted to blood" Cytokine NA NA 24400 21000 "Cluster 57: Lung - Lung function" "Cluster 49: Hindbrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 48: Smooth muscle cells - Signal transduction" 4 Vesicles "CAB078457: AB_2532532, HPA058610: AB_2683777" "unprognostic (2.22e-2)" "unprognostic (9.32e-2)" "unprognostic (6.12e-2)" "unprognostic (3.56e-2)" "unprognostic (1.94e-2)" "unprognostic (2.48e-1)" "unprognostic (3.70e-3)" "unprognostic (3.12e-3)" "unprognostic (8.51e-2)" "unprognostic (8.46e-2)" "unprognostic (2.53e-3)" "unprognostic (5.39e-3)" "unprognostic (7.81e-2)" "unprognostic (3.76e-1)" "unprognostic (2.77e-1)" "unprognostic (3.01e-2)" "unprognostic (7.49e-2)" BMP5 ENSG00000112175 "Bone morphogenetic protein 5" P22003 6 55753653-55875590 "Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "placenta: 68.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 15.2;Fibroblasts: 11.1;Microglial cells: 25.0;Pancreatic endocrine cells: 39.1;Skeletal myocytes: 8.8;Smooth muscle cells: 21.7" "Cancer enhanced" "Detected in many" "lung cancer: 2.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 15.3" "Liver - Hepatic stellate cells, Pancreas - Alpha cells, Pancreas - Beta cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted - unknown location" Cytokine NA NA "Cluster 58: Placenta - Pregnancy" "Cluster 49: Hindbrain - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 50: Connective tissue cells - ECM organization" "unprognostic (2.84e-4)" "unprognostic (9.07e-4)" "unprognostic (3.50e-1)" "unprognostic (1.27e-1)" "unprognostic (6.21e-2)" "unprognostic (1.58e-1)" "unprognostic (2.39e-3)" "unprognostic (1.29e-1)" "unprognostic (1.20e-1)" "unprognostic (6.76e-2)" "unprognostic (4.43e-3)" "unprognostic (3.15e-1)" "unprognostic (1.26e-1)" "unprognostic (1.30e-1)" "unprognostic (4.76e-2)" BTNL9 "BTN8, FLJ32535" ENSG00000165810 "Butyrophilin like 9" Q6UXG8 5 181040225-181061521 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 242.8;breast: 193.5" "Cell type enriched" "Detected in many" 6 "Adipocytes: 794.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lymphoma: 9.6" "Adipose visceral - Endothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA043429 Approved "Nuclear membrane,Vesicles" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 7: Adipose tissue - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "Nuclear membrane" Vesicles "HPA043429: AB_10961264" "unprognostic (2.69e-1)" "unprognostic (1.44e-2)" "unprognostic (5.76e-2)" "prognostic unfavorable (7.51e-4)" "unprognostic (2.07e-1)" "unprognostic (1.43e-1)" "prognostic favorable (1.55e-9)" "unprognostic (2.15e-2)" "unprognostic (8.51e-2)" "unprognostic (1.78e-1)" "unprognostic (1.93e-3)" "unprognostic (1.38e-1)" "unprognostic (1.03e-1)" "unprognostic (2.71e-2)" "unprognostic (3.43e-1)" "unprognostic (2.50e-1)" "unprognostic (4.56e-2)" BUB3 BUB3L ENSG00000154473 "BUB3 mitotic checkpoint protein" O43684 10 123154402-123170467 "Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Meiosis, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 322.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003601, CAB037075" Supported Supported Nucleoplasm NA Yes 39000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 49: Hindbrain - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 6 Nucleoplasm "CAB037075: AB_1078310, HPA003601: AB_1078309" "unprognostic (7.82e-2)" "prognostic favorable (2.04e-4)" "unprognostic (9.07e-2)" "unprognostic (1.83e-1)" "unprognostic (7.93e-2)" "unprognostic (8.60e-2)" "prognostic unfavorable (4.45e-5)" "unprognostic (6.04e-3)" "unprognostic (9.41e-2)" "unprognostic (6.30e-3)" "unprognostic (2.69e-2)" "unprognostic (1.37e-2)" "prognostic unfavorable (3.81e-7)" "unprognostic (8.80e-2)" "unprognostic (7.64e-2)" "unprognostic (1.51e-1)" "unprognostic (7.71e-2)" C22orf39 MGC74441 ENSG00000242259 "Chromosome 22 open reading frame 39" Q6P5X5 22 19351368-19447711 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 114.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073701 Approved "Endoplasmic reticulum" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 49: Hindbrain - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" 36 "Endoplasmic reticulum" "HPA073701: AB_2686627" "unprognostic (4.97e-2)" "unprognostic (2.67e-2)" "unprognostic (1.87e-1)" "prognostic favorable (2.16e-4)" "unprognostic (1.27e-2)" "unprognostic (6.53e-2)" "unprognostic (5.07e-2)" "unprognostic (1.95e-3)" "unprognostic (8.93e-2)" "unprognostic (1.51e-2)" "unprognostic (1.45e-3)" "unprognostic (5.34e-3)" "prognostic favorable (1.44e-4)" "unprognostic (6.51e-2)" "unprognostic (2.92e-1)" "unprognostic (1.32e-2)" "unprognostic (5.32e-2)" CALB2 CAL2 ENSG00000172137 "Calbindin 2" P22676 16 71358713-71390436 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 97.3;brain: 306.6" "Group enriched" "Detected in many" 6 "granulocytes: 214.1;Mesothelial cells: 480.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 31.5;pancreatic cancer: 36.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Lung - Mast cells, Stomach - Fibroblasts, Testis - Leydig cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "thalamus: 647.9" "CAB000106, HPA007305, HPA007306" Enhanced Supported Enhanced Cytosol NA NA 9600 "Cluster 65: Cerebellum - Nervous system development" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 30: Granulocytes - Unknown function" Cytosol "CAB000106: AB_2068519, HPA007305: AB_1078386, HPA007306: AB_1078385" "unprognostic (1.10e-1)" "unprognostic (1.90e-2)" "prognostic unfavorable (5.78e-5)" "unprognostic (1.75e-3)" "unprognostic (5.80e-2)" "unprognostic (1.43e-1)" "unprognostic (1.59e-1)" "unprognostic (4.55e-3)" "unprognostic (4.28e-1)" "unprognostic (1.32e-1)" "unprognostic (3.06e-3)" "unprognostic (1.35e-2)" "unprognostic (5.54e-4)" "unprognostic (1.97e-3)" "unprognostic (6.30e-2)" "unprognostic (4.72e-2)" "unprognostic (1.04e-2)" CAPN1 "CANP, CANPL1, muCANP, muCL" ENSG00000014216 "Calpain 1" P07384 11 65180566-65212006 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 268.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005992 Enhanced Supported Cytosol NA NA 9100000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 7 Cytosol "HPA005992: AB_1845924" "unprognostic (2.07e-1)" "unprognostic (2.15e-1)" "unprognostic (2.69e-1)" "unprognostic (1.40e-1)" "unprognostic (4.06e-2)" "unprognostic (1.10e-1)" "unprognostic (1.91e-2)" "unprognostic (2.48e-2)" "unprognostic (7.23e-2)" "unprognostic (2.23e-2)" "prognostic unfavorable (4.30e-4)" "unprognostic (3.33e-1)" "prognostic favorable (7.06e-8)" "unprognostic (5.70e-3)" "unprognostic (1.51e-1)" "unprognostic (1.86e-1)" "unprognostic (2.98e-1)" CAPN5 "ADNIV, HTRA3, nCL-3, VRNI" ENSG00000149260 "Calpain 5" O15484 11 77066961-77126155 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 59.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 140.1;Gastric mucus-secreting cells: 71.9;Intestinal goblet cells: 104.6;Paneth cells: 68.4;Proximal enterocytes: 65.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.3" "Lineage enriched" "Detected in single" 4 "T-cells: 1.3" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Liver - Hepatocytes, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Gastric mucous cells, Testis - Sertoli cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033237, HPA072319" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 11: T-cells - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 49: Hindbrain - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" Nucleoplasm Cytosol "CAB033237: AB_2069673, HPA072319: AB_2686512" "unprognostic (6.81e-3)" "unprognostic (1.31e-1)" "unprognostic (3.36e-2)" "prognostic unfavorable (2.16e-6)" "unprognostic (3.47e-3)" "unprognostic (1.34e-1)" "unprognostic (1.13e-1)" "unprognostic (5.30e-2)" "unprognostic (2.52e-1)" "unprognostic (2.21e-2)" "unprognostic (5.35e-3)" "unprognostic (4.64e-1)" "unprognostic (3.17e-3)" "unprognostic (8.58e-3)" "unprognostic (3.25e-1)" "unprognostic (2.31e-2)" "unprognostic (2.30e-3)" CARD10 "BIMP1, CARMA3" ENSG00000100065 "Caspase recruitment domain family member 10" Q9BWT7 22 37490362-37519542 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 34.9" "Cell type enhanced" "Detected in many" "Adipocytes: 23.2;Ductal cells: 25.3;Endothelial cells: 28.4;Intestinal goblet cells: 26.1;Lymphatic endothelial cells: 29.0;Proximal enterocytes: 31.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Prostate - Endothelial cells, Testis - Sertoli cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029359, HPA055612" Approved Approved "Vesicles,Intermediate filaments,Cytosol" No No "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" 83 "Vesicles, Intermediate filaments" Cytosol "HPA029359: AB_10601354, HPA055612: AB_2682861" "unprognostic (9.12e-3)" "unprognostic (2.28e-1)" "unprognostic (7.51e-2)" "prognostic favorable (3.47e-4)" "unprognostic (4.54e-1)" "unprognostic (2.70e-2)" "prognostic unfavorable (7.73e-6)" "unprognostic (3.66e-2)" "unprognostic (7.70e-2)" "unprognostic (1.93e-1)" "unprognostic (2.16e-1)" "unprognostic (3.68e-2)" "unprognostic (2.78e-2)" "unprognostic (2.87e-2)" "unprognostic (4.34e-1)" "unprognostic (4.31e-2)" "unprognostic (9.69e-2)" CAST ENSG00000153113 Calpastatin P20810 5 96525267-96779595 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Thiol protease inhibitor" "Cancer-related genes, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1367.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009491, HPA036881, HPA036882, HPA075906" Enhanced Enhanced "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA 17000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 21: Early spermatids - Spermatogenesis" 1 "Endoplasmic reticulum, Cytosol" "Plasma membrane" "CAB009491: AB_2259755, HPA036881: AB_2675359, HPA036882: AB_2675360, HPA075906: " "unprognostic (2.17e-1)" "unprognostic (1.39e-1)" "unprognostic (2.44e-2)" "unprognostic (1.91e-2)" "unprognostic (4.68e-2)" "unprognostic (1.45e-1)" "unprognostic (3.79e-1)" "unprognostic (4.53e-3)" "unprognostic (1.94e-2)" "unprognostic (6.11e-3)" "prognostic unfavorable (9.27e-5)" "unprognostic (2.66e-2)" "unprognostic (1.69e-2)" "prognostic unfavorable (1.20e-5)" "unprognostic (1.16e-1)" "unprognostic (2.79e-1)" "prognostic unfavorable (4.98e-4)" CCDC137 MGC16597 ENSG00000185298 "Coiled-coil domain containing 137" Q6PK04 17 81666737-81673904 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052637, HPA053914" Uncertain Enhanced "Nucleoli,Mitotic chromosome" Yes No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 49: Hindbrain - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 12: Squamous epithelial cells - Keratinization" 1 "Nucleoli, Mitotic chromosome" "HPA052637: AB_2681894, HPA053914: AB_2682306" "unprognostic (3.04e-1)" "unprognostic (5.82e-2)" "unprognostic (1.76e-1)" "unprognostic (3.07e-2)" "unprognostic (1.68e-2)" "unprognostic (2.24e-1)" "prognostic unfavorable (1.35e-7)" "prognostic unfavorable (8.32e-4)" "unprognostic (2.21e-2)" "unprognostic (8.33e-3)" "unprognostic (1.26e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (1.16e-7)" "unprognostic (4.26e-2)" "unprognostic (2.01e-1)" "unprognostic (3.93e-1)" "unprognostic (1.39e-1)" CCDC197 "C14orf48, LINC00521" ENSG00000175699 "Coiled-coil domain containing 197" 14 93987225-94008863 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "testis: 7.8" "Group enriched" "Detected in some" 88 "Early spermatids: 108.3;Late spermatids: 371.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Gallbladder cancer: 1.2" "Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 49: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 36: Late spermatids - Unknown function" "unprognostic (5.01e-1)" "unprognostic (1.09e-1)" CCDC69 "DKFZP434C171, FLJ13705" ENSG00000198624 "Coiled-coil domain containing 69" A6NI79 5 151181052-151224093 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 340.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 142.6;dendritic cells: 177.9;monocytes: 126.8;NK-cells: 135.5;Plasma cells: 142.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 9 "Leukemia: 41.0;lymphoma: 129.6;Myeloma: 60.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Prostate - Smooth muscle cells, Skin - Macrophages" "Region enhanced" "Detected in some" "cerebellum: 4.8" "Low region specificity" "Detected in all" "HPA043648, HPA052896" Uncertain Approved "Golgi apparatus,Plasma membrane,Actin filaments" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 77: Plasma cells - Protein processing" "Plasma membrane" "Golgi apparatus, Actin filaments" "HPA043648: AB_10795877, HPA052896: AB_2681983" "prognostic favorable (3.21e-4)" "unprognostic (2.60e-2)" "unprognostic (1.28e-1)" "unprognostic (2.78e-2)" "unprognostic (5.62e-2)" "unprognostic (8.63e-3)" "unprognostic (3.07e-2)" "unprognostic (6.48e-2)" "unprognostic (2.00e-1)" "unprognostic (9.29e-2)" "unprognostic (3.85e-2)" "unprognostic (1.55e-2)" "unprognostic (3.67e-1)" "unprognostic (4.31e-2)" "unprognostic (3.69e-1)" "unprognostic (2.93e-1)" "unprognostic (2.01e-1)" CCNQ "CycM, FAM58A" ENSG00000262919 "Cyclin Q" Q8N1B3 X 153587925-153600045 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Cyclin "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 112.0;Syncytiotrophoblasts: 107.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050137, HPA059843" Uncertain Approved Nucleoplasm,Cytosol Yes No "Cluster 22: Eosinophils - Transcription" "Cluster 23: Non-specific - Cellular respiration" "Cluster 49: Hindbrain - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 4: Extravillous trophoblasts - Unknown function" Nucleoplasm Cytosol "HPA050137: AB_2681029, HPA059843: AB_2684140" "unprognostic (3.94e-1)" "unprognostic (1.94e-2)" "unprognostic (7.36e-2)" "unprognostic (2.92e-1)" "unprognostic (5.08e-2)" "unprognostic (1.02e-2)" "unprognostic (1.47e-3)" "unprognostic (2.12e-1)" "unprognostic (8.50e-3)" "unprognostic (2.08e-2)" "unprognostic (1.57e-2)" "unprognostic (1.90e-1)" "unprognostic (1.20e-1)" "unprognostic (8.75e-2)" "unprognostic (2.31e-1)" "unprognostic (2.71e-2)" "unprognostic (5.25e-2)" CD8B CD8B1 ENSG00000172116 "CD8b molecule" P10966 2 86815339-86861924 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "lymphoid tissue: 447.5" "Cell type enriched" "Detected in many" 11 "T-cells: 159.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "memory CD8 T-cell: 602.5;naive CD8 T-cell: 1058.1" "Lineage enriched" "Detected in all" 25 "T-cells: 1058.1" "Group enriched" "Detected in some" 9 "Leukemia: 8.7;Myeloma: 33.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Stomach - T-cells, Thyroid - T-cells" "CAB004353, HPA029164" Enhanced Supported "Plasma membrane" "Intracellular and membrane" Immunity NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 71: Thymus - Adaptive immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 19: NK-cells - Adaptive immune response" "Plasma membrane" "CAB004353: AB_627211, HPA029164: AB_2672936" "unprognostic (1.83e-3)" "unprognostic (1.98e-3)" "unprognostic (2.22e-2)" "prognostic favorable (7.88e-7)" "unprognostic (6.23e-2)" "unprognostic (7.05e-3)" "unprognostic (1.11e-2)" "unprognostic (2.59e-2)" "unprognostic (5.50e-3)" "unprognostic (5.91e-2)" "unprognostic (9.25e-2)" "unprognostic (4.60e-1)" "prognostic unfavorable (7.11e-6)" "unprognostic (7.84e-2)" "unprognostic (3.00e-1)" "unprognostic (1.86e-2)" "unprognostic (4.33e-2)" CD8B2 CD8BP ENSG00000254126 "CD8b2 molecule" A6NJW9 2 106487364-106544297 "Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "kidney: 1.9;lymphoid tissue: 7.2" "Cell type enhanced" "Detected in single" "T-cells: 1.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 9 "memory CD8 T-cell: 18.8;naive CD8 T-cell: 30.8" "Lineage enriched" "Detected in many" 14 "T-cells: 30.8" "Group enriched" "Detected in some" 12 "breast cancer: 7.7;Myeloma: 18.9" "Skin - Fibroblast_2" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 49: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 7: T-cells - T-cell receptor" "unprognostic (9.34e-3)" "unprognostic (7.84e-2)" "unprognostic (2.32e-2)" "unprognostic (3.41e-2)" "unprognostic (2.10e-1)" "unprognostic (5.54e-2)" "unprognostic (1.18e-1)" "unprognostic (5.27e-1)" "unprognostic (1.28e-2)" "unprognostic (1.21e-1)" "unprognostic (2.27e-1)" "unprognostic (2.76e-2)" "unprognostic (1.21e-1)" "unprognostic (1.41e-1)" "unprognostic (6.90e-2)" "unprognostic (9.67e-3)" CDH23 "CDHR23, DFNB12, USH1D" ENSG00000107736 "Cadherin related 23" Q9H251 10 71396920-71815947 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Hearing, Sensory transduction, Vision" "Deafness, Disease variant, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 34.2" "Cell type enhanced" "Detected in many" "Early spermatids: 52.7;Late spermatids: 82.5;Microglial cells: 32.2;monocytes: 75.0;Muller glia cells: 81.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 26.8;non-classical monocyte: 38.2" "Lineage enriched" "Detected in many" 4 "monocytes: 38.2" "Cancer enhanced" "Detected in many" "Bone cancer: 9.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA017232 Approved NA NA 950000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 64: Neuronal - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 10: Muller glia cells - Visual perception" "HPA017232: AB_1845903" "unprognostic (6.76e-2)" "unprognostic (2.86e-3)" "unprognostic (3.82e-2)" "unprognostic (3.13e-3)" "unprognostic (1.07e-1)" "unprognostic (5.52e-2)" "unprognostic (7.93e-2)" "unprognostic (2.88e-1)" "unprognostic (6.44e-3)" "unprognostic (4.67e-2)" "unprognostic (2.05e-1)" "unprognostic (9.23e-3)" "unprognostic (2.14e-3)" "unprognostic (2.33e-2)" "unprognostic (1.72e-1)" "unprognostic (1.70e-2)" "prognostic favorable (3.40e-4)" CDH7 ENSG00000081138 "Cadherin 7" Q9ULB5 18 65750252-65890337 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 4.3;retina: 3.5" "Group enriched" "Detected in some" 5 "Excitatory neurons: 44.0;Horizontal cells: 57.3;Inhibitory neurons: 107.2;Muller glia cells: 34.0" "Cancer enhanced" "Detected in single" "prostate cancer: 0.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 3.3;Sarcoma: 3.3" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061419 Supported NA NA "Cluster 28: Neuronal - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 8: Neurons - Neuronal signaling" "HPA061419: AB_2684511" "unprognostic (2.81e-3)" "unprognostic (6.95e-2)" "unprognostic (2.26e-1)" "unprognostic (2.24e-2)" "unprognostic (3.45e-2)" "unprognostic (2.41e-1)" "unprognostic (3.95e-3)" "unprognostic (2.88e-1)" "unprognostic (4.28e-4)" "unprognostic (2.70e-2)" "unprognostic (1.49e-1)" "unprognostic (1.72e-1)" CHP1 "CHP, p22, p24, Sid470p, SLC9A1BP" ENSG00000187446 "Calcineurin like EF-hand protein 1" Q99653 15 41230839-41281887 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Protein kinase inhibitor" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 423.4;Distal tubular cells: 424.1;Hepatocytes: 343.0;Proximal enterocytes: 403.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006616 Approved Approved Vesicles NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 5: Enterocytes - Absorption" 1 Vesicles "HPA006616: AB_1857461" "unprognostic (2.06e-2)" "unprognostic (3.26e-1)" "unprognostic (2.84e-1)" "prognostic favorable (9.63e-4)" "unprognostic (7.29e-2)" "unprognostic (3.74e-1)" "prognostic favorable (4.07e-6)" "unprognostic (2.20e-1)" "unprognostic (7.46e-2)" "unprognostic (3.26e-2)" "unprognostic (1.26e-3)" "unprognostic (2.79e-1)" "prognostic favorable (2.79e-6)" "unprognostic (1.06e-1)" "unprognostic (1.49e-1)" "unprognostic (4.62e-3)" "unprognostic (2.04e-1)" CHRM2 ENSG00000181072 "Cholinergic receptor muscarinic 2" P08172 7 136868652-137020255 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 34.9;intestine: 20.5" "Group enriched" "Detected in some" 7 "Cardiomyocytes: 71.7;Excitatory neurons: 47.5;Inhibitory neurons: 113.6" "Cancer enhanced" "Detected in single" "stomach cancer: 0.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Neuroblastoma: 11.0" "Heart muscle - Cardiomyocytes, Liver - Hepatic stellate cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB022338, HPA029795" Approved NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 49: Hindbrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 69: Neurons - Neuronal signaling" "CAB022338: , HPA029795: AB_10601357" "unprognostic (3.51e-2)" "unprognostic (3.73e-4)" "unprognostic (5.77e-2)" "unprognostic (1.78e-2)" "unprognostic (1.97e-1)" "unprognostic (4.00e-1)" "unprognostic (2.69e-1)" "unprognostic (1.43e-2)" "unprognostic (1.80e-1)" "unprognostic (1.35e-3)" CHST8 GALNAC4ST-1 ENSG00000124302 "Carbohydrate sulfotransferase 8" Q9H2A9 19 33621953-33773509 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 22 "brain: 17.7;pituitary gland: 62.2" "Cell type enhanced" "Detected in some" "Early spermatids: 9.3;Excitatory neurons: 11.4;Granulosa cells: 10.8;Horizontal cells: 13.2;Late spermatids: 54.1;Oligodendrocyte precursor cells: 11.3;Pancreatic endocrine cells: 13.6" "Group enriched" "Detected in many" 4 "breast cancer: 4.1;glioma: 4.9;testis cancer: 3.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Neuroblastoma: 12.0" "Pancreas - Beta cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA016004 Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 49: Hindbrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 36: Late spermatids - Unknown function" 2 "HPA016004: AB_1846731" "unprognostic (1.00e-1)" "unprognostic (6.58e-2)" "unprognostic (1.21e-1)" "unprognostic (1.45e-2)" "unprognostic (9.44e-2)" "unprognostic (2.96e-2)" "unprognostic (1.15e-2)" "unprognostic (5.75e-2)" "unprognostic (8.41e-2)" "unprognostic (1.16e-1)" "unprognostic (2.83e-2)" "unprognostic (1.54e-1)" "unprognostic (6.98e-8)" "unprognostic (9.37e-3)" "unprognostic (2.61e-1)" "unprognostic (3.28e-1)" "unprognostic (3.87e-2)" CIB4 ENSG00000157884 "Calcium and integrin binding family member 4" A0PJX0 2 26581205-26641366 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 16.8" "Cell type enriched" "Detected in some" 9 "Early spermatids: 246.3" "Cancer enhanced" "Detected in some" "renal cancer: 0.7;thyroid cancer: 0.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA036130, HPA036131" Uncertain NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 49: Hindbrain - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 18: Early spermatids - Unknown function" 5 "HPA036130: AB_10670709, HPA036131: AB_2674959" "unprognostic (3.63e-3)" "unprognostic (1.78e-1)" "unprognostic (2.61e-4)" "unprognostic (1.63e-1)" "unprognostic (1.66e-1)" "unprognostic (1.27e-1)" "unprognostic (4.29e-4)" "unprognostic (1.57e-1)" "unprognostic (3.19e-5)" "unprognostic (1.20e-2)" "unprognostic (3.63e-1)" "unprognostic (1.76e-3)" "unprognostic (3.50e-1)" CPNE9 KIAA4217 ENSG00000144550 "Copine family member 9" Q8IYJ1 3 9703826-9729908 "Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 36.7" "Group enriched" "Detected in some" 5 "Excitatory neurons: 27.2;Late spermatids: 62.3" "Cancer enriched" "Detected in single" 4 "testis cancer: 1.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "intermediate monocyte: 1.0" "Lineage enhanced" "Detected in single" "monocytes: 1.0" "Not detected" "Not detected" "Colon - Colon enteroendocrine cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060813 Approved "Plasma membrane,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 65: Cerebellum - Nervous system development" "Cluster 49: Hindbrain - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 63: Late spermatids - Spermatogenesis" Cytosol "Plasma membrane" "HPA060813: " "unprognostic (2.96e-1)" "unprognostic (4.75e-2)" "unprognostic (1.34e-1)" "unprognostic (5.04e-3)" "unprognostic (1.10e-1)" "unprognostic (1.96e-1)" "unprognostic (2.13e-3)" "unprognostic (1.03e-2)" "unprognostic (3.19e-2)" "unprognostic (1.06e-1)" "unprognostic (1.20e-4)" "unprognostic (2.67e-2)" "unprognostic (5.44e-4)" "unprognostic (1.47e-2)" "unprognostic (8.59e-2)" "unprognostic (3.45e-1)" "unprognostic (7.48e-2)" CRACD "CRAD, KIAA1211" ENSG00000109265 "Capping protein inhibiting regulator of actin dynamics" Q6ZU35 4 56049098-56330609 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 18.8;testis: 28.4" "Cell type enhanced" "Detected in many" "Astrocytes: 66.9;Early spermatids: 51.7;Inhibitory neurons: 254.6;Late spermatids: 147.3;Oligodendrocyte precursor cells: 123.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 33.0" "Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043249, HPA048148" Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA 59000 "Cluster 46: Testis - Spermatogenesis" "Cluster 49: Hindbrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 65: Neurons - Synaptic function" Nucleoplasm "Golgi apparatus" "HPA043249: AB_2678388, HPA048148: AB_2680286" "unprognostic (1.65e-1)" "unprognostic (1.98e-1)" "unprognostic (7.74e-3)" "unprognostic (1.31e-1)" "unprognostic (6.04e-1)" "unprognostic (6.44e-2)" "unprognostic (1.98e-2)" "unprognostic (3.24e-2)" "unprognostic (1.34e-1)" "unprognostic (3.12e-2)" "unprognostic (1.11e-1)" "unprognostic (1.09e-1)" "unprognostic (8.05e-6)" "unprognostic (1.02e-1)" "unprognostic (6.54e-2)" "unprognostic (2.79e-2)" "unprognostic (2.93e-1)" CRTAC1 "ASPIC1, CEP-68, FLJ10320" ENSG00000095713 "Cartilage acidic protein 1" Q9NQ79 10 97865000-98030828 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 37.0;lung: 48.4;seminal vesicle: 32.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 125.1;Basal prostatic cells: 67.9;Inhibitory neurons: 61.2;Oligodendrocyte precursor cells: 51.4;Secretory cells: 94.3" "Cancer enhanced" "Detected in many" "melanoma: 43.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 6.0;skin cancer: 4.9" "Colon - Enteric glia cells, Liver - Vascular Endothelial cells, Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008175 Enhanced "Secreted to extracellular matrix" "No annotated function" NA NA 550000000 "Cluster 64: Neuronal - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 72: Alveolar cells - Lung function" 4 "HPA008175: AB_1847254" "unprognostic (2.55e-1)" "unprognostic (6.41e-3)" "unprognostic (4.90e-3)" "prognostic unfavorable (5.01e-6)" "unprognostic (2.54e-1)" "unprognostic (6.96e-3)" "unprognostic (9.30e-2)" "unprognostic (9.13e-2)" "unprognostic (1.02e-2)" "unprognostic (3.01e-1)" "unprognostic (7.66e-2)" "unprognostic (1.69e-1)" "prognostic favorable (1.85e-4)" "unprognostic (6.70e-4)" "unprognostic (1.05e-2)" "unprognostic (3.29e-3)" "prognostic favorable (1.51e-4)" CSK ENSG00000103653 "C-terminal Src kinase" P41240 15 74782080-74803197 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 165.2" "Cell type enhanced" "Detected in all" "B-cells: 129.2;monocytes: 172.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011203, HPA026488, HPA028425" Approved Approved Enhanced Vesicles,Cytosol No No 150000 "Cluster 25: Non-specific - Unknown function" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 49: Hindbrain - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 73: B-cells - B-cell function" 10 "Vesicles, Cytosol" "CAB011203: AB_259070, HPA026488: AB_1847273, HPA028425: AB_10600899" "unprognostic (1.05e-1)" "prognostic favorable (5.14e-5)" "unprognostic (2.59e-3)" "prognostic favorable (8.22e-4)" "unprognostic (4.15e-2)" "unprognostic (4.11e-2)" "unprognostic (1.87e-1)" "unprognostic (2.96e-1)" "unprognostic (2.20e-1)" "unprognostic (1.31e-1)" "unprognostic (4.12e-2)" "unprognostic (4.61e-2)" "prognostic unfavorable (1.74e-4)" "prognostic favorable (1.07e-4)" "unprognostic (1.44e-1)" "unprognostic (1.01e-1)" "unprognostic (6.29e-2)" CT45A10 ENSG00000269586 "Cancer/testis antigen family 45 member A10" P0DMU9 X 135881063-135893444 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 9.0" "Group enriched" "Detected in some" 28 "Spermatocytes: 13.2;Spermatogonia: 38.4" "Cancer enhanced" "Detected in some" "ovarian cancer: 1.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Spermatocytes" "HPA044735, HPA044757, HPA046872, HPA046987" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 49: Hindbrain - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 67: Spermatogonia - Spermatogenesis" 4 "Nucleoplasm, Nucleoli" "HPA044735: AB_2679065, HPA044757: AB_2679075, HPA046872: AB_2679849, HPA046987: AB_2679893" "unprognostic (3.55e-1)" "unprognostic (7.08e-3)" "unprognostic (2.08e-1)" CUBN "gp280, IFCR, MGA1" ENSG00000107611 Cubilin O60494 10 16823966-17129811 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cholesterol metabolism, Endocytosis, Lipid metabolism, Protein transport, Steroid metabolism, Sterol metabolism, Transport" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "kidney: 135.4" "Group enriched" "Detected in many" 6 "Proximal enterocytes: 186.0;Proximal tubular cells: 276.0" "Cancer enriched" "Detected in some" 15 "renal cancer: 24.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Rhabdoid: 17.7" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Skeletal muscle - Fibroblasts, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004133, HPA043854" Enhanced "Intracellular and membrane" Receptor NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 49: Hindbrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 38: Proximal tubular cells - Transmembrane transport" 2 "HPA004133: AB_2732398, HPA043854: AB_2732510" "unprognostic (1.75e-1)" "unprognostic (2.35e-1)" "unprognostic (2.12e-3)" "unprognostic (8.61e-4)" "unprognostic (9.54e-2)" "unprognostic (2.78e-2)" "unprognostic (2.88e-2)" "unprognostic (7.03e-2)" "unprognostic (1.24e-1)" "unprognostic (7.16e-2)" "unprognostic (1.98e-2)" "unprognostic (2.47e-1)" "prognostic favorable (1.12e-4)" "unprognostic (6.24e-3)" "unprognostic (1.97e-1)" "unprognostic (2.00e-1)" "unprognostic (1.93e-1)" CYP26B1 P450RAI-2 ENSG00000003137 "Cytochrome P450 family 26 subfamily B member 1" Q9NR63 2 72129238-72147862 "Disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.3;skin 1: 30.4" "Group enriched" "Detected in many" 5 "Leydig cells: 78.3;Peritubular cells: 217.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "pons: 111.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 38.6" "Breast - Adipocytes (Breast), Liver - Vascular Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA012567 Uncertain Approved Cytosol "Intracellular and membrane" Enzyme No No "Cluster 65: Cerebellum - Nervous system development" "Cluster 49: Hindbrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 48: Smooth muscle cells - Signal transduction" 1 Cytosol "HPA012567: AB_1847429" "unprognostic (1.70e-1)" "unprognostic (1.05e-1)" "unprognostic (8.76e-2)" "unprognostic (2.19e-4)" "unprognostic (3.46e-2)" "unprognostic (4.40e-1)" "unprognostic (2.17e-4)" "unprognostic (8.41e-2)" "unprognostic (1.51e-1)" "unprognostic (1.40e-1)" "unprognostic (7.55e-3)" "unprognostic (1.52e-1)" "unprognostic (2.62e-2)" "unprognostic (1.77e-1)" "unprognostic (1.55e-1)" "unprognostic (9.44e-3)" "unprognostic (2.04e-2)" CYP2S1 ENSG00000167600 "Cytochrome P450 family 2 subfamily S member 1" Q96SQ9 19 41193210-41207539 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 98.4;stomach 1: 117.2" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 90.2;Intestinal goblet cells: 34.6;Langerhans cells: 82.1;Proximal enterocytes: 41.7;Schwann cells: 73.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "classical monocyte: 24.8;myeloid DC: 84.5" "Group enriched" "Detected in many" 131 "dendritic cells: 84.5;monocytes: 24.8" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Mesothelial cells, Heart muscle - Macrophages, Liver - Kupffer cells, Prostate - Prostate basal glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049227, HPA069248" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 25: Small intestine - Absorption" "Cluster 49: Hindbrain - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 28: Dendritic cells - Antigen presentation" 2 "Endoplasmic reticulum" "HPA049227: AB_2680681, HPA069248: AB_2732128" "unprognostic (1.49e-2)" "unprognostic (7.45e-2)" "unprognostic (2.45e-2)" "unprognostic (6.03e-2)" "unprognostic (3.93e-2)" "unprognostic (7.46e-2)" "unprognostic (1.27e-2)" "unprognostic (4.85e-2)" "unprognostic (2.18e-1)" "unprognostic (1.54e-2)" "unprognostic (6.25e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.60e-6)" "unprognostic (1.06e-1)" "unprognostic (1.10e-1)" "unprognostic (1.02e-1)" "unprognostic (7.66e-2)" CYP51A1 "CP51, CYP51, CYPL1, LDM, P450-14DM, P450L1" ENSG00000001630 "Cytochrome P450 family 51 subfamily A member 1" Q16850 7 92084987-92134803 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Monooxygenase, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 196.0" "Cell type enhanced" "Detected in many" "Early spermatids: 52.6;Kupffer cells: 56.0;Oligodendrocytes: 49.4;Squamous epithelial cells: 50.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Liver - Hepatocytes, Lung - Alveolar cells type 2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041325, HPA043508" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 69: Liver - Oxidoreductase activity" "Cluster 49: Hindbrain - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 62: Hepatocytes - Metabolism" "Endoplasmic reticulum" "HPA041325: AB_2677411, HPA043508: AB_2678520" "unprognostic (6.68e-2)" "prognostic unfavorable (6.12e-4)" "unprognostic (3.48e-2)" "unprognostic (1.18e-2)" "unprognostic (7.82e-2)" "unprognostic (3.60e-2)" "unprognostic (1.02e-1)" "unprognostic (1.97e-1)" "unprognostic (9.84e-2)" "unprognostic (1.36e-1)" "unprognostic (9.75e-2)" "unprognostic (1.34e-1)" "unprognostic (1.59e-9)" "unprognostic (1.82e-1)" "unprognostic (2.73e-1)" "unprognostic (5.13e-2)" "unprognostic (1.09e-3)" DDX43 "CT13, DKFZp434H2114, HAGE" ENSG00000080007 "DEAD-box helicase 43" Q9NXZ2 6 73394828-73417566 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "placenta: 4.7;testis: 19.0" "Group enriched" "Detected in many" 7 "Oocytes: 75.0;Spermatocytes: 47.1;Spermatogonia: 46.0" "Cancer enriched" "Detected in many" 15 "testis cancer: 13.0" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 8.7" "Testis - Spermatocytes" HPA031381 Enhanced NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 21: Testis - Unknown function" "Cluster 49: Hindbrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 31: Spermatocytes - Spermatogenesis" 2 "HPA031381: AB_10601885" "unprognostic (4.03e-3)" "unprognostic (8.20e-2)" "unprognostic (2.06e-1)" "unprognostic (1.01e-1)" "unprognostic (2.19e-1)" "unprognostic (3.59e-4)" "unprognostic (1.64e-2)" "unprognostic (3.11e-2)" "unprognostic (1.20e-1)" "unprognostic (2.15e-1)" "unprognostic (3.12e-1)" "unprognostic (3.08e-1)" "unprognostic (1.19e-3)" "unprognostic (1.02e-1)" "unprognostic (2.68e-1)" "unprognostic (1.58e-1)" "unprognostic (8.78e-2)" DEFB131A "DEFB-31, DEFB131" ENSG00000186146 "Defensin beta 131A" P59861 4 9444414-9450666 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "epididymis: 130.2" "Group enriched" "Detected in some" 20 "Basal prostatic cells: 15.2;Proximal enterocytes: 4.4" "Cancer enriched" "Detected in single" 18 "thyroid cancer: 1.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Secreted in other tissues" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 49: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 3: Basal prostatic cells - Lipid metabolism" 1 "unprognostic (2.11e-1)" DHCR7 SLOS ENSG00000172893 "7-dehydrocholesterol reductase" Q9UBM7 11 71428193-71452868 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 157.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 105.8;Basal respiratory cells: 76.4;Hepatocytes: 128.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Lung - Alveolar cells type 2, Skin - Sebaceous gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044280 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 62: Hepatocytes - Metabolism" "Endoplasmic reticulum" "HPA044280: AB_10794893" "unprognostic (1.76e-1)" "unprognostic (1.50e-3)" "unprognostic (1.32e-2)" "unprognostic (7.16e-3)" "unprognostic (2.69e-1)" "unprognostic (2.18e-3)" "unprognostic (8.57e-3)" "unprognostic (3.02e-2)" "unprognostic (4.91e-2)" "unprognostic (1.13e-1)" "unprognostic (1.08e-2)" "unprognostic (5.45e-2)" "prognostic favorable (6.93e-7)" "unprognostic (1.73e-1)" "unprognostic (1.01e-1)" "unprognostic (8.15e-2)" "prognostic unfavorable (5.67e-4)" DHRS7 "retDSR4, SDR34C1" ENSG00000100612 "Dehydrogenase/reductase 7" Q9Y394 14 60144119-60169856 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 594.0" "Cell type enhanced" "Detected in all" "Prostatic glandular cells: 1021.8;Proximal enterocytes: 836.1;Serous glandular cells: 508.0" "Cancer enriched" "Detected in all" 5 "prostate cancer: 199.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Macrophages, Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031121, HPA078401" Enhanced Approved Nucleoplasm,Mitochondria No No "Cluster 35: Neutrophils - Protein binding" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 75: Serous glandular cells - Salivary secretion" 2 "Nucleoplasm, Mitochondria" "HPA031121: AB_10600803, HPA078401: " "prognostic favorable (6.42e-4)" "unprognostic (5.20e-2)" "unprognostic (6.70e-3)" "unprognostic (1.67e-1)" "unprognostic (2.69e-1)" "prognostic unfavorable (2.51e-4)" "unprognostic (4.65e-2)" "unprognostic (4.31e-2)" "unprognostic (2.62e-1)" "prognostic unfavorable (7.99e-4)" "unprognostic (1.73e-1)" "unprognostic (1.59e-1)" "prognostic favorable (1.92e-10)" "unprognostic (8.35e-3)" "unprognostic (1.48e-1)" "unprognostic (1.07e-1)" "unprognostic (3.61e-1)" DMKN ZD52F10 ENSG00000161249 Dermokine Q6E0U4 19 35497220-35513658 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "skin 1: 4645.8" "Cell type enriched" "Detected in many" 8 "Suprabasal keratinocytes: 4475.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 11.7" "Group enriched" "Detected in many" 5 "NK-cells: 11.7;T-cells: 6.4" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2" "Region enhanced" "Detected in all" "basal ganglia: 51.9" "Low region specificity" "Detected in some" "HPA029406, HPA071641" Enhanced Approved Nucleoplasm,Cytosol "Secreted in other tissues" "No annotated function" NA NA 47000000 "Cluster 15: NK-cells - Unknown function" "Cluster 13: Skin - Cornification" "Cluster 49: Hindbrain - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 12: Squamous epithelial cells - Keratinization" 6 "Nucleoplasm, Cytosol" "HPA029406: AB_10603661, HPA071641: " "unprognostic (5.70e-2)" "unprognostic (2.36e-2)" "unprognostic (3.64e-2)" "unprognostic (1.03e-1)" "unprognostic (1.28e-2)" "unprognostic (2.48e-2)" "unprognostic (3.82e-2)" "unprognostic (3.23e-1)" "unprognostic (1.03e-1)" "unprognostic (8.82e-2)" "unprognostic (2.54e-1)" "unprognostic (9.93e-2)" "prognostic favorable (5.37e-6)" "unprognostic (3.50e-1)" "unprognostic (1.58e-1)" "unprognostic (1.29e-1)" "unprognostic (2.08e-1)" DOK3 FLJ22570 ENSG00000146094 "Docking protein 3" Q7L591 5 177501904-177511274 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 92.6;lymphoid tissue: 115.6" "Group enriched" "Detected in some" 6 "B-cells: 31.1;granulocytes: 23.5;Hofbauer cells: 57.9;Kupffer cells: 45.6;Macrophages: 35.3;monocytes: 53.8;Plasma cells: 39.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 134.3" "Group enriched" "Detected in many" 6 "B-cells: 37.3;granulocytes: 134.3;monocytes: 78.1" "Group enriched" "Detected in all" 6 "Leukemia: 72.6;lymphoma: 95.9;Myeloma: 24.7" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Kidney - Macrophages, Lung - Neutrophil_2, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA077312 Enhanced Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge,Cytosol" Yes NA 240000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 74: Neutrophils - Degranulation" 3 "Plasma membrane" "Nucleoplasm, Cytokinetic bridge, Cytosol" "HPA077312: AB_2732339" "unprognostic (2.21e-2)" "unprognostic (1.14e-2)" "unprognostic (2.05e-2)" "unprognostic (5.74e-3)" "unprognostic (2.32e-2)" "unprognostic (1.34e-3)" "unprognostic (4.17e-2)" "unprognostic (2.20e-1)" "unprognostic (8.00e-2)" "unprognostic (1.32e-1)" "unprognostic (1.21e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (3.82e-11)" "unprognostic (1.34e-1)" "unprognostic (7.25e-2)" "unprognostic (1.55e-1)" "unprognostic (3.78e-2)" DRGX "DRG11, PRRXL1" ENSG00000165606 "Dorsal root ganglia homeobox" A6NNA5 10 49364066-49396089 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 9 "adrenal gland: 5.2;brain: 2.1" "Cell type enhanced" "Detected in some" "Langerhans cells: 2.0;Late spermatids: 1.2;Melanocytes: 1.7" "Low cancer specificity" "Detected in single" "Group enriched" "Detected in many" 9 "medulla oblongata: 9.3;pons: 22.2;spinal cord: 17.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Neuroblastoma: 5.3;Sarcoma: 2.7" "Region enriched" "Detected in single" 6 "pons and medulla: 3.9" "Group enriched" "Detected in some" 10 "cerebral cortex: 5.2;hippocampal formation: 2.1;medulla oblongata: 3.1;spinal cord: 4.9" HPA043978 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 49: Hindbrain - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 34: Neurons - Neuronal signaling" "Nucleoplasm, Nucleoli" Cytosol "HPA043978: AB_10961154" "unprognostic (1.42e-2)" "unprognostic (5.68e-2)" "unprognostic (3.92e-2)" "unprognostic (1.23e-2)" "unprognostic (1.74e-3)" "unprognostic (1.58e-1)" "unprognostic (4.54e-2)" "unprognostic (3.74e-2)" "unprognostic (8.91e-2)" "unprognostic (1.60e-1)" "unprognostic (4.09e-2)" DUSP23 "DUSP25, FLJ20442" ENSG00000158716 "Dual specificity phosphatase 23" Q9BVJ7 1 159780932-159782543 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Mucus glandular cells: 609.9;Oocytes: 393.3;Proximal tubular cells: 895.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028211, HPA045792" Approved Supported Nucleoplasm NA NA 22000 "Cluster 29: Non-specific - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 49: Hindbrain - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 38: Proximal tubular cells - Transmembrane transport" 7 Nucleoplasm "HPA028211: AB_2672522, HPA045792: AB_10961133" "unprognostic (1.52e-1)" "unprognostic (4.12e-1)" "unprognostic (1.40e-3)" "unprognostic (3.33e-2)" "unprognostic (4.36e-2)" "unprognostic (3.22e-1)" "prognostic unfavorable (3.06e-4)" "unprognostic (3.16e-1)" "unprognostic (4.62e-1)" "unprognostic (3.33e-3)" "unprognostic (4.72e-2)" "unprognostic (3.75e-2)" "prognostic unfavorable (2.59e-5)" "unprognostic (8.58e-2)" "unprognostic (2.84e-2)" "unprognostic (7.47e-2)" "unprognostic (1.39e-1)" EBP "CDPX2, CHO2, CPX, CPXD" ENSG00000147155 "EBP cholestenol delta-isomerase" Q15125 X 48521799-48528716 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Isomerase "Cataract, Disease variant, Dwarfism, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 318.4" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 242.4;Hepatocytes: 634.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003130 Approved Supported "Nuclear membrane,Endoplasmic reticulum" NA Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 83: Liver - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 62: Hepatocytes - Metabolism" 159 "Nuclear membrane, Endoplasmic reticulum" "HPA003130: AB_1078717" "unprognostic (1.90e-1)" "unprognostic (2.64e-2)" "unprognostic (2.80e-1)" "unprognostic (6.27e-2)" "unprognostic (3.41e-1)" "unprognostic (1.64e-1)" "unprognostic (1.13e-1)" "unprognostic (1.15e-1)" "unprognostic (1.34e-1)" "unprognostic (1.87e-1)" "unprognostic (4.72e-2)" "unprognostic (1.47e-1)" "unprognostic (5.14e-2)" "unprognostic (4.04e-2)" "unprognostic (5.39e-2)" "unprognostic (4.13e-1)" "unprognostic (1.36e-1)" EGFLAM "AGRINL, AGRNL, FLJ39155, PIKA" ENSG00000164318 "EGF like, fibronectin type III and laminin G domains" Q63HQ2 5 38258409-38465480 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 116.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 110.4;Early spermatids: 46.5;Late spermatids: 49.7;Leydig cells: 161.0;Rod photoreceptor cells: 38.6;Sertoli cells: 38.1;Smooth muscle cells: 47.7" "Cancer enhanced" "Detected in all" "testis cancer: 6.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 37.6" "Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA066577 Approved "Secreted - unknown location" "No annotated function" NA NA "Cluster 19: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 48: Smooth muscle cells - Signal transduction" "HPA066577: " "unprognostic (2.05e-1)" "unprognostic (4.81e-2)" "unprognostic (1.01e-1)" "unprognostic (1.38e-3)" "unprognostic (1.08e-2)" "unprognostic (3.63e-3)" "unprognostic (6.31e-2)" "unprognostic (2.83e-1)" "unprognostic (2.08e-2)" "unprognostic (1.71e-3)" "unprognostic (1.12e-1)" "unprognostic (5.80e-2)" "prognostic unfavorable (4.47e-5)" "unprognostic (7.02e-6)" "unprognostic (2.60e-1)" "unprognostic (9.90e-2)" "unprognostic (1.04e-2)" EIF4E2 "4EHP, EIF4EL3, IF4e" ENSG00000135930 "Eukaryotic translation initiation factor 4E family member 2" O60573 2 232550659-232583644 "Predicted intracellular proteins" "Protein biosynthesis, RNA-mediated gene silencing, Translation regulation" "Initiation factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 294.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019253, HPA077074" Enhanced Mitochondria,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 15: Non-specific - Mixed function" 32 Mitochondria Cytosol "HPA019253: AB_1848092, HPA077074: " "unprognostic (3.44e-2)" "unprognostic (2.70e-1)" "unprognostic (1.30e-1)" "unprognostic (3.83e-2)" "unprognostic (1.63e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (2.38e-4)" "unprognostic (1.42e-1)" "unprognostic (5.62e-3)" "unprognostic (1.42e-2)" "unprognostic (1.31e-1)" "unprognostic (1.21e-2)" "unprognostic (1.36e-2)" "unprognostic (7.74e-2)" "unprognostic (3.34e-3)" "unprognostic (1.88e-1)" "unprognostic (9.38e-2)" ENSG00000267952 ENSG00000267952 "Novel transcript" 19 7507052-7519622 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "retina: 4.9;skeletal muscle: 11.9" "Cell type enhanced" "Detected in some" "Late spermatids: 3.5;Rod photoreceptor cells: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 14 "testis cancer: 10.8" NA NA "Cluster 3: Non-specific - Unknown function" "Cluster 49: Hindbrain - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 63: Late spermatids - Spermatogenesis" "unprognostic (4.56e-1)" "unprognostic (8.56e-2)" ENSG00000285471 ENSG00000285471 "Novel protein" 17 5772926-6080792 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 24 "Oocytes: 5.9" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Sarcoma: 14.7" NA NA "Cluster 49: Hindbrain - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 44: Oocytes - Unknown function" ENSG00000289710 ENSG00000289710 "Novel protein, similar to CD24 molecule CD52" 1 30576655-30576825 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Region enhanced" "Detected in some" "midbrain: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 49: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" EPN3 "FLJ20778, MGC129899" ENSG00000049283 "Epsin 3" Q9H201 17 50532682-50543750 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 34.9;stomach 1: 36.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 76.2;Distal enterocytes: 31.4;Gastric mucus-secreting cells: 41.9;Squamous epithelial cells: 32.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 48.6" "Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA055546, HPA063224" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 49: Hindbrain - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 24: Cytotrophoblasts - Mitochondria" Vesicles Nucleoplasm "HPA055546: AB_2682844, HPA063224: AB_2684964" "unprognostic (1.91e-2)" "unprognostic (1.99e-2)" "unprognostic (2.41e-1)" "unprognostic (2.91e-2)" "unprognostic (1.25e-3)" "unprognostic (2.06e-1)" "unprognostic (5.70e-3)" "unprognostic (7.62e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-1)" "unprognostic (6.66e-3)" "unprognostic (1.00e-2)" "prognostic favorable (1.53e-5)" "unprognostic (1.45e-1)" "unprognostic (1.16e-1)" "unprognostic (4.90e-1)" "unprognostic (3.52e-3)" EPS8 ENSG00000151491 "Epidermal growth factor receptor pathway substrate 8" Q12929 12 15620134-15882329 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 264.9;Smooth muscle cells: 262.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 22.3" "Lineage enriched" "Detected in all" 4 "monocytes: 22.3" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003897, HPA050209" Approved Approved "Plasma membrane" NA NA 17000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 62: Connective tissue - ECM organization" "Cluster 49: Hindbrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 48: Smooth muscle cells - Signal transduction" 14 "Plasma membrane" "HPA003897: AB_1848224, HPA050209: " "unprognostic (6.16e-2)" "unprognostic (1.79e-1)" "unprognostic (1.27e-2)" "unprognostic (5.43e-2)" "unprognostic (2.46e-1)" "unprognostic (1.04e-1)" "unprognostic (5.81e-2)" "unprognostic (1.68e-1)" "unprognostic (2.01e-1)" "unprognostic (1.57e-3)" "prognostic unfavorable (3.33e-7)" "unprognostic (2.68e-1)" "prognostic favorable (1.45e-7)" "unprognostic (7.47e-3)" "unprognostic (7.20e-2)" "prognostic favorable (5.11e-4)" "unprognostic (1.79e-2)" ESRRG "ERR-gamma, ERRg, NR3B3" ENSG00000196482 "Estrogen related receptor gamma" P62508 1 216503246-217137755 "FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 28.0;parathyroid gland: 44.8;retina: 35.0;stomach 1: 34.2" "Group enriched" "Detected in many" 4 "Astrocytes: 313.7;Excitatory neurons: 401.0;Inhibitory neurons: 477.2;Oligodendrocyte precursor cells: 367.4;Oligodendrocytes: 203.5;Syncytiotrophoblasts: 201.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 14.7" "Lung - Respiratory ciliated cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Skin - Eccrine sweat gland cells, Stomach - Parietal cells, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044678 Uncertain Approved Nucleoplasm No NA "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 49: Hindbrain - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 8: Neurons - Neuronal signaling" 7 Nucleoplasm "HPA044678: AB_10963215" "unprognostic (6.48e-2)" "unprognostic (1.11e-1)" "unprognostic (7.06e-2)" "unprognostic (7.32e-2)" "unprognostic (2.34e-1)" "unprognostic (5.48e-2)" "unprognostic (1.66e-1)" "unprognostic (1.13e-1)" "unprognostic (4.55e-2)" "unprognostic (2.88e-1)" "unprognostic (2.35e-1)" "unprognostic (1.79e-2)" "prognostic favorable (1.13e-11)" "unprognostic (3.04e-1)" "unprognostic (2.55e-1)" "unprognostic (3.65e-4)" "unprognostic (2.05e-1)" ESYT1 "FAM62A, KIAA0747, MBC2" ENSG00000139641 "Extended synaptotagmin 1" Q9BSJ8 12 56118250-56144674 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016858, HPA076926" Approved Supported "Endoplasmic reticulum" NA NA 720000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 62: Connective tissue - ECM organization" "Cluster 49: Hindbrain - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 19: NK-cells - Adaptive immune response" 2 "Endoplasmic reticulum" "HPA016858: AB_1848404, HPA076926: AB_2686819" "unprognostic (5.02e-2)" "unprognostic (3.62e-2)" "unprognostic (6.26e-3)" "unprognostic (1.87e-1)" "unprognostic (3.28e-2)" "unprognostic (8.44e-2)" "unprognostic (5.41e-2)" "unprognostic (1.55e-1)" "unprognostic (1.39e-2)" "unprognostic (1.77e-1)" "unprognostic (6.85e-3)" "unprognostic (1.29e-1)" "prognostic favorable (3.86e-4)" "unprognostic (3.04e-2)" "unprognostic (8.43e-3)" "unprognostic (1.52e-2)" "unprognostic (3.98e-2)" EVPL EVPK ENSG00000167880 Envoplakin Q92817 17 76004502-76027306 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 273.3;skin 1: 142.9;vagina: 98.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 42.4;Basal keratinocytes: 39.8;Squamous epithelial cells: 102.7;Suprabasal keratinocytes: 172.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Mast cells, Adipose visceral - Mesothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "Region enhanced" "Detected in single" "spinal cord: 1.4" "CAB002220, HPA053969" Enhanced Supported "Intermediate filaments,Cytosol" NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" "Intermediate filaments" Cytosol "CAB002220: AB_563701, HPA053969: AB_2682326" "unprognostic (2.10e-1)" "unprognostic (1.58e-1)" "unprognostic (1.41e-1)" "unprognostic (4.21e-1)" "unprognostic (1.05e-2)" "unprognostic (1.87e-2)" "unprognostic (1.70e-1)" "unprognostic (1.11e-1)" "unprognostic (1.94e-1)" "unprognostic (1.44e-1)" "unprognostic (7.40e-3)" "unprognostic (2.64e-1)" "unprognostic (2.40e-2)" "unprognostic (2.31e-1)" "unprognostic (3.47e-1)" "unprognostic (7.93e-2)" "unprognostic (3.09e-2)" F10 ENSG00000126218 "Coagulation factor X" P00742 13 113122799-113149529 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 156.1" "Cell type enhanced" "Detected in many" "Fibroblasts: 109.1;Hepatocytes: 170.7;Leydig cells: 217.7;Peritubular cells: 232.6;Smooth muscle cells: 57.6" "Cancer enriched" "Detected in many" 11 "liver cancer: 95.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Adrenocortical cancer: 6.9;liver cancer: 16.8" "Breast - Fibroblasts, Colon - Fibroblasts, Liver - Hepatocytes, Pancreas - Alpha cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" "Blood coagulation" NA NA 13000000000 "Cluster 83: Liver - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 53: Fibroblasts - ECM organization" 3 "unprognostic (4.18e-2)" "unprognostic (1.07e-1)" "unprognostic (7.62e-2)" "unprognostic (9.88e-2)" "unprognostic (9.44e-2)" "unprognostic (1.15e-2)" "unprognostic (4.90e-2)" "unprognostic (1.02e-2)" "unprognostic (2.54e-1)" "unprognostic (1.24e-1)" "prognostic favorable (1.82e-5)" "unprognostic (6.39e-2)" "prognostic unfavorable (5.14e-5)" "unprognostic (6.60e-2)" "unprognostic (1.21e-1)" "unprognostic (3.87e-2)" "unprognostic (2.23e-3)" FAM110A "bA371L19.3, C20orf55" ENSG00000125898 "Family with sequence similarity 110 member A" Q9BQ89 20 833715-857463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 68.9" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 161.4;granulocytes: 63.9;Langerhans cells: 81.4;monocytes: 102.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "basophil: 546.1;eosinophil: 163.7;intermediate monocyte: 160.5;non-classical monocyte: 249.3" "Group enriched" "Detected in all" 9 "granulocytes: 546.1;monocytes: 249.3" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB034110, HPA069240" Uncertain Uncertain Nucleoplasm,Vesicles,Cytosol Yes Yes "Cluster 25: Non-specific - Unknown function" "Cluster 13: Skin - Cornification" "Cluster 49: Hindbrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 57: Platelets - Hemostasis" 41 "Nucleoplasm, Vesicles" Cytosol "CAB034110: AB_1562838, HPA069240: AB_2686103" "unprognostic (6.33e-2)" "unprognostic (2.53e-2)" "unprognostic (1.57e-2)" "unprognostic (3.43e-2)" "unprognostic (1.81e-1)" "unprognostic (3.37e-2)" "unprognostic (4.90e-3)" "unprognostic (5.55e-2)" "unprognostic (6.01e-2)" "unprognostic (4.78e-2)" "unprognostic (2.35e-2)" "unprognostic (2.47e-1)" "prognostic unfavorable (4.42e-4)" "unprognostic (9.64e-3)" "unprognostic (1.17e-2)" "unprognostic (6.42e-3)" "unprognostic (4.21e-3)" FAM163A "C1orf76, MGC16664, NDSP" ENSG00000143340 "Family with sequence similarity 163 member A" Q96GL9 1 179743291-179816198 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 15.6;pituitary gland: 28.8;testis: 12.3" "Group enriched" "Detected in some" 5 "Early spermatids: 36.3;Late spermatids: 49.3" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in all" "pons: 44.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "Adrenocortical cancer: 45.6;Neuroblastoma: 56.7" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 28: Neuronal - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 36: Late spermatids - Unknown function" 17 "unprognostic (8.74e-3)" "unprognostic (3.42e-2)" "unprognostic (1.32e-2)" "unprognostic (3.24e-1)" "unprognostic (2.62e-1)" "unprognostic (1.66e-1)" "unprognostic (5.67e-6)" "unprognostic (5.56e-2)" "unprognostic (1.52e-1)" "unprognostic (2.40e-2)" "unprognostic (3.81e-3)" "unprognostic (9.14e-2)" "unprognostic (7.75e-5)" "unprognostic (1.67e-2)" "unprognostic (2.83e-1)" "unprognostic (1.60e-1)" "unprognostic (4.98e-2)" FAM43A FLJ90022 ENSG00000185112 "Family with sequence similarity 43 member A" Q8N2R8 3 194685883-194689037 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 53.6" "Cell type enhanced" "Detected in many" "Adipocytes: 86.3;Endothelial cells: 100.4;Extravillous trophoblasts: 93.2;Prostatic glandular cells: 84.9;Syncytiotrophoblasts: 162.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 4.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048345 Uncertain Approved Vesicles NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 Vesicles "HPA048345: AB_2680367" "unprognostic (1.61e-1)" "unprognostic (1.11e-1)" "unprognostic (9.18e-2)" "unprognostic (1.90e-2)" "unprognostic (5.71e-3)" "unprognostic (5.13e-3)" "unprognostic (9.80e-2)" "unprognostic (8.28e-2)" "unprognostic (4.96e-2)" "unprognostic (1.38e-1)" "unprognostic (3.92e-3)" "unprognostic (1.74e-1)" "unprognostic (2.14e-1)" "unprognostic (1.15e-1)" "unprognostic (1.45e-1)" "unprognostic (2.91e-3)" "prognostic unfavorable (9.96e-4)" FDFT1 SQS ENSG00000079459 "Farnesyl-diphosphate farnesyltransferase 1" P37268 8 11795573-11839304 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 465.5;Ionocytes: 394.7;Oocytes: 407.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008874 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 80: Non-specific - Endocytosis" "Cluster 49: Hindbrain - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 35: Respiratory epithelial cells - Unknown function" 12 "Endoplasmic reticulum" "HPA008874: AB_1078844" "unprognostic (2.33e-1)" "unprognostic (2.60e-1)" "prognostic favorable (4.92e-5)" "unprognostic (1.29e-2)" "unprognostic (1.46e-2)" "unprognostic (1.71e-1)" "unprognostic (8.10e-2)" "unprognostic (1.01e-1)" "unprognostic (2.39e-1)" "unprognostic (2.45e-1)" "unprognostic (2.31e-3)" "unprognostic (2.57e-1)" "prognostic favorable (6.59e-9)" "unprognostic (2.28e-1)" "unprognostic (4.06e-2)" "unprognostic (3.86e-1)" "unprognostic (2.06e-1)" FDPS ENSG00000160752 "Farnesyl diphosphate synthase" P14324 1 155308748-155320666 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Host-virus interaction, Isoprene biosynthesis, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Transferase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 344.6" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 958.5;Distal enterocytes: 509.2;Ionocytes: 764.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028200 Approved Approved Nucleoplasm,Cytosol NA NA 1500000 "Cluster 25: Non-specific - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 35: Respiratory epithelial cells - Unknown function" 6 Cytosol Nucleoplasm "HPA028200: AB_10612109" "unprognostic (1.23e-1)" "unprognostic (8.46e-3)" "unprognostic (2.47e-2)" "unprognostic (6.57e-2)" "unprognostic (4.58e-2)" "unprognostic (2.84e-2)" "prognostic unfavorable (7.35e-4)" "unprognostic (4.21e-2)" "unprognostic (6.78e-3)" "unprognostic (1.64e-3)" "unprognostic (7.19e-2)" "unprognostic (2.25e-2)" "unprognostic (1.11e-2)" "unprognostic (8.25e-2)" "unprognostic (2.07e-1)" "unprognostic (5.65e-2)" "unprognostic (8.44e-2)" FERMT1 "C20orf42, FLJ20116, KIND1, UNC112A, URP1" ENSG00000101311 "FERM domain containing kindlin 1" Q9BQL6 20 6074845-6123214 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 30.9" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 100.4;Cytotrophoblasts: 70.0;Oligodendrocyte precursor cells: 215.5;Squamous epithelial cells: 67.5;Suprabasal keratinocytes: 63.6;Undifferentiated cells: 81.6" "Cancer enhanced" "Detected in all" "colorectal cancer: 59.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (other), Thyroid - Thyroid glandular cells" "Region enriched" "Detected in single" 5 "hippocampal formation: 2.0" "Not detected" "Not detected" "HPA039778, HPA041966" Approved NA NA "Cluster 45: Intestine - Digestion" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" "HPA039778: AB_10805593, HPA041966: AB_10795387" "unprognostic (1.08e-3)" "unprognostic (4.63e-2)" "unprognostic (1.03e-1)" "unprognostic (3.64e-3)" "unprognostic (1.75e-3)" "unprognostic (2.82e-1)" "unprognostic (9.49e-2)" "unprognostic (1.53e-3)" "unprognostic (2.13e-1)" "unprognostic (1.83e-1)" "prognostic unfavorable (6.60e-4)" "unprognostic (4.38e-2)" "unprognostic (1.31e-1)" "unprognostic (2.11e-2)" "unprognostic (2.04e-1)" "unprognostic (4.60e-2)" "unprognostic (5.33e-2)" FHDC1 "INF1, KIAA1727" ENSG00000137460 "FH2 domain containing 1" Q9C0D6 4 152936323-152979671 "Predicted intracellular proteins" "Cilium biogenesis/degradation" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.5;parathyroid gland: 17.0;thyroid gland: 15.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 47.3;Erythroid cells: 60.0;Syncytiotrophoblasts: 80.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008527 Uncertain NA NA "Cluster 40: Non-specific - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 72: Alveolar cells - Lung function" "HPA008527: AB_2104099" "unprognostic (5.42e-2)" "unprognostic (8.12e-2)" "unprognostic (2.42e-2)" "unprognostic (1.99e-3)" "unprognostic (1.16e-1)" "unprognostic (2.25e-1)" "unprognostic (2.95e-4)" "unprognostic (1.37e-1)" "unprognostic (2.15e-1)" "unprognostic (1.80e-1)" "unprognostic (1.25e-2)" "unprognostic (2.40e-1)" "prognostic favorable (1.33e-5)" "unprognostic (4.04e-2)" "unprognostic (1.90e-1)" "unprognostic (9.36e-2)" "unprognostic (1.30e-1)" FOXP4 FLJ40908 ENSG00000137166 "Forkhead box P4" Q8IVH2 6 41546381-41602384 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 51.3;Intestinal goblet cells: 43.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007176, HPA076256" Approved Approved Nucleoplasm NA NA "Cluster 18: Non-specific - Ribosome" "Cluster 49: Hindbrain - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 16: Intestinal goblet cells - Mucin production" 2 Nucleoplasm "HPA007176: AB_1078911, HPA076256: " "unprognostic (8.28e-2)" "unprognostic (2.90e-2)" "unprognostic (1.12e-1)" "prognostic unfavorable (1.17e-6)" "unprognostic (3.20e-2)" "unprognostic (2.96e-3)" "prognostic unfavorable (9.72e-4)" "unprognostic (2.13e-2)" "unprognostic (7.86e-3)" "unprognostic (4.36e-2)" "unprognostic (2.22e-3)" "unprognostic (9.31e-2)" "unprognostic (1.65e-1)" "unprognostic (2.41e-2)" "unprognostic (1.53e-1)" "unprognostic (1.01e-1)" "unprognostic (1.95e-2)" GBP6 DKFZp686G0786 ENSG00000183347 "Guanylate binding protein family member 6" Q6ZN66 1 89364059-89388160 "Predicted intracellular proteins" "Immunity, Innate immunity" "Antimicrobial, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "esophagus: 318.1" "Group enriched" "Detected in some" 8 "Basal keratinocytes: 275.5;Squamous epithelial cells: 438.5;Suprabasal keratinocytes: 875.1" "Group enriched" "Detected in many" 7 "cervical cancer: 21.7;head and neck cancer: 38.1;lung cancer: 14.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Esophageal cancer: 13.5;Gallbladder cancer: 16.3;head and neck cancer: 8.8" "Lung - Respiratory ciliated cells" "Low region specificity" "Detected in single" HPA027744 Enhanced NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" "HPA027744: AB_10602809" "unprognostic (7.60e-3)" "unprognostic (6.83e-2)" "unprognostic (1.78e-2)" "unprognostic (1.31e-1)" "unprognostic (1.13e-1)" "unprognostic (7.05e-3)" "unprognostic (5.85e-2)" "unprognostic (5.66e-2)" "unprognostic (1.62e-1)" "unprognostic (4.34e-1)" "unprognostic (7.99e-4)" "unprognostic (1.63e-1)" "unprognostic (2.04e-6)" "unprognostic (1.43e-1)" "unprognostic (1.03e-1)" "unprognostic (3.41e-1)" "unprognostic (3.91e-3)" GCLM GLCLR ENSG00000023909 "Glutamate-cysteine ligase modifier subunit" P48507 1 93885199-93909456 "Cancer-related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Glutathione biosynthesis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 47.0" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 157.0;Erythroid cells: 205.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in all" 9 "Gallbladder cancer: 586.6" "Adipose subcutaneous - Adipocytes (Subcutaneous), Skin - Outer root sheath cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009568, HPA023696, CAB040554" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 1100000 "Cluster 1: T-cells - Unknown function" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 1: Erythroid cells - Oxygen transport" 2 "Nucleoplasm, Cytosol" "Plasma membrane" "CAB009568: AB_2107835, CAB040554: , HPA023696: AB_1849560" "unprognostic (2.31e-1)" "unprognostic (7.92e-2)" "unprognostic (8.85e-3)" "unprognostic (1.56e-2)" "unprognostic (2.83e-2)" "unprognostic (4.64e-2)" "prognostic unfavorable (9.83e-6)" "unprognostic (2.37e-1)" "unprognostic (1.07e-1)" "unprognostic (3.53e-1)" "unprognostic (3.51e-2)" "unprognostic (3.89e-2)" "unprognostic (2.19e-2)" "unprognostic (1.09e-2)" "unprognostic (1.79e-1)" "unprognostic (2.43e-1)" "unprognostic (2.34e-3)" GCOM1 "FLJ30973, GRINL1A, MYZAP-POLR2M" ENSG00000137878 "GCOM1, MYZAP-POLR2M combined locus" 15 57591908-57714745 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 19.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 35.9;Glandular and luminal cells: 12.8;Paneth cells: 10.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "naive B-cell: 1.4;naive CD4 T-cell: 1.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "HPA039827, HPA068141" Approved Approved Nucleoplasm NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 37: Glandular & Luminal cells - Unknown function" Nucleoplasm "HPA039827: AB_10673364, HPA068141: AB_2685962" "unprognostic (1.10e-1)" "unprognostic (3.62e-4)" "unprognostic (1.10e-1)" "unprognostic (5.43e-3)" "unprognostic (1.31e-3)" "unprognostic (1.55e-1)" "unprognostic (1.29e-1)" "unprognostic (7.69e-4)" "unprognostic (1.22e-1)" "unprognostic (3.22e-3)" "unprognostic (3.13e-2)" "unprognostic (1.27e-1)" "unprognostic (2.61e-1)" "unprognostic (4.03e-2)" "unprognostic (7.44e-2)" "unprognostic (1.67e-1)" "unprognostic (5.78e-2)" GHDC LGP1 ENSG00000167925 "GH3 domain containing" Q8N2G8 17 42188799-42194532 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Skeletal muscle - Macrophages, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031650 Uncertain "Intracellular and membrane" "No annotated function" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 47: Spleen - Immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "HPA031650: AB_10601014" "unprognostic (2.30e-2)" "unprognostic (1.63e-1)" "unprognostic (2.60e-1)" "prognostic favorable (3.21e-4)" "prognostic unfavorable (6.81e-5)" "unprognostic (5.13e-2)" "unprognostic (3.35e-2)" "unprognostic (2.56e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (5.20e-4)" "unprognostic (6.69e-3)" "unprognostic (5.18e-2)" "prognostic favorable (2.00e-6)" "unprognostic (2.08e-1)" "unprognostic (7.93e-2)" "unprognostic (9.66e-2)" "unprognostic (4.02e-2)" GLYATL1 "FLJ34646, MGC15397" ENSG00000166840 "Glycine-N-acyltransferase like 1" Q969I3 11 58905398-59043527 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 30 "kidney: 135.0;liver: 527.0" "Group enriched" "Detected in some" 9 "Hepatocytes: 287.9;Proximal tubular cells: 517.2" "Group enriched" "Detected in some" 8 "liver cancer: 14.1;prostate cancer: 13.3;renal cancer: 10.1" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 19 "prostate cancer: 68.5" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Sebaceous gland cells" HPA039501 Supported Uncertain "Golgi apparatus,Cytosol" NA NA "Cluster 1: Liver & Kidney - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 56: Proximal tubular cells - Amino acid metabolism" "Golgi apparatus" Cytosol "HPA039501: AB_2676545" "unprognostic (9.46e-3)" "unprognostic (5.33e-2)" "unprognostic (3.90e-5)" "unprognostic (3.93e-3)" "unprognostic (3.54e-3)" "unprognostic (2.17e-1)" "prognostic favorable (3.69e-4)" "unprognostic (3.62e-1)" "unprognostic (2.51e-1)" "unprognostic (1.05e-1)" "unprognostic (2.08e-1)" "unprognostic (2.92e-1)" "prognostic favorable (3.03e-5)" "unprognostic (1.50e-1)" "unprognostic (1.01e-1)" "unprognostic (1.86e-2)" "unprognostic (4.55e-2)" GNGT2 GNG9 ENSG00000167083 "G protein subunit gamma transducin 2" O14610 17 49202791-49210574 "Predicted intracellular proteins, RAS pathway related proteins, Transporters" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "retina: 152.1" "Cell type enriched" "Detected in some" 14 "Cone photoreceptor cells: 560.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 67.1" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 25.5" "Low region specificity" "Detected in all" HPA043381 Enhanced NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 76: Retina - Visual perception" "Cluster 49: Hindbrain - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 66: Photoreceptor cells - Visual perception" "HPA043381: AB_2678455" "unprognostic (9.11e-2)" "unprognostic (4.09e-3)" "unprognostic (1.99e-2)" "unprognostic (4.62e-5)" "unprognostic (1.34e-1)" "unprognostic (3.20e-3)" "unprognostic (1.75e-1)" "unprognostic (7.37e-2)" "unprognostic (1.30e-2)" "unprognostic (2.11e-2)" "unprognostic (2.08e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (3.11e-4)" "unprognostic (1.35e-1)" "unprognostic (1.19e-1)" "unprognostic (6.92e-2)" "unprognostic (1.23e-1)" GOLGA8H GOLGA6L11 ENSG00000261794 "Golgin A8 family member H" P0CJ92 15 30604028-30617752 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "testis: 6.2" "Cell type enhanced" "Detected in some" "Astrocytes: 6.5;Early spermatids: 21.7;Inhibitory neurons: 3.0;Late spermatids: 2.6;Microglial cells: 4.5;Spermatocytes: 5.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 46: Testis - Spermatogenesis" "Cluster 49: Hindbrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 18: Early spermatids - Unknown function" "unprognostic (4.32e-3)" "unprognostic (7.13e-2)" "unprognostic (4.86e-2)" "unprognostic (2.92e-1)" "unprognostic (2.71e-1)" "unprognostic (7.33e-2)" "unprognostic (6.91e-2)" "unprognostic (1.12e-1)" "unprognostic (2.49e-1)" "unprognostic (1.05e-1)" "unprognostic (6.44e-3)" "unprognostic (2.85e-2)" "unprognostic (1.66e-1)" "unprognostic (2.22e-2)" "unprognostic (1.10e-1)" "unprognostic (6.08e-2)" "unprognostic (1.14e-1)" GOLGA8K ENSG00000249931 "Golgin A8 family member K" D6RF30 15 32389599-32403292 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 4 "testis: 6.4" "Cell type enriched" "Detected in some" 15 "Early spermatids: 16.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Adrenocortical cancer: 1.6;Leukemia: 1.2" "Testis - Early spermatids" NA NA "Cluster 46: Testis - Spermatogenesis" "Cluster 49: Hindbrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 18: Early spermatids - Unknown function" "unprognostic (2.47e-1)" "unprognostic (3.27e-1)" "unprognostic (4.01e-2)" "unprognostic (1.09e-2)" "unprognostic (6.62e-2)" "unprognostic (7.35e-2)" "unprognostic (2.86e-1)" "unprognostic (5.75e-2)" "unprognostic (1.37e-1)" "unprognostic (1.21e-1)" "unprognostic (1.97e-1)" "unprognostic (7.00e-3)" "unprognostic (4.81e-2)" "unprognostic (1.18e-2)" "unprognostic (9.81e-2)" GPR142 PGR2 ENSG00000257008 "G protein-coupled receptor 142" Q7Z601 17 74367458-74372600 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "stomach 1: 1.7" "Cell type enriched" "Detected in single" 6 "Enteroendocrine cells: 1.1" "Cancer enriched" "Detected in single" 4 "pancreatic cancer: 1.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Alpha cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA031392 Uncertain Uncertain "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 49: Hindbrain - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 20: Enteroendocrine cells - Hormone signaling" "Plasma membrane, Cytosol" "Cell Junctions" "HPA031392: AB_10601935" "unprognostic (6.81e-2)" "unprognostic (1.75e-1)" "unprognostic (1.98e-1)" "unprognostic (1.34e-1)" "unprognostic (1.36e-1)" "unprognostic (6.54e-5)" "unprognostic (4.16e-2)" "unprognostic (4.85e-7)" "unprognostic (3.95e-2)" "unprognostic (7.72e-4)" "unprognostic (1.93e-1)" "unprognostic (1.68e-3)" GRIK1 "GluK1, GLUR5" ENSG00000171189 "Glutamate ionotropic receptor kainate type subunit 1" P39086 21 29536933-29940033 "FDA approved drug targets, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "adrenal gland: 12.1;brain: 10.8;retina: 38.0" "Group enriched" "Detected in some" 12 "Inhibitory neurons: 2151.1;Oligodendrocyte precursor cells: 809.4" "Cancer enriched" "Detected in some" 5 "glioma: 4.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Breast glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014623, HPA073879" Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 49: Hindbrain - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 65: Neurons - Synaptic function" "Plasma membrane" Vesicles "HPA014623: AB_1850305, HPA073879: " "unprognostic (1.39e-1)" "unprognostic (6.54e-2)" "unprognostic (1.32e-1)" "unprognostic (1.04e-2)" "unprognostic (1.03e-3)" "unprognostic (1.56e-1)" "unprognostic (1.07e-1)" "unprognostic (2.12e-3)" "unprognostic (1.25e-1)" "unprognostic (8.77e-2)" "unprognostic (4.89e-3)" "unprognostic (1.20e-3)" "unprognostic (1.47e-8)" "unprognostic (2.09e-1)" "unprognostic (2.68e-1)" "unprognostic (1.09e-1)" "unprognostic (3.15e-3)" GTPBP3 "FLJ14700, GTPBG3, MSS1, MTGP1, THDF1" ENSG00000130299 "GTP binding protein 3, mitochondrial" Q969Y2 19 17334920-17342731 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "tRNA processing" "Cardiomyopathy, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042158 Approved Supported Mitochondria NA NA "Cluster 18: Non-specific - Translation" "Cluster 66: Non-specific - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 39: Non-specific - Basic cellular processes" 18 Mitochondria "HPA042158: AB_10964400" "unprognostic (1.52e-1)" "unprognostic (1.08e-2)" "unprognostic (2.23e-1)" "unprognostic (3.08e-3)" "unprognostic (1.34e-1)" "unprognostic (2.18e-2)" "prognostic unfavorable (1.86e-4)" "unprognostic (6.32e-2)" "unprognostic (1.82e-1)" "unprognostic (2.70e-2)" "unprognostic (3.25e-2)" "prognostic unfavorable (2.81e-4)" "prognostic unfavorable (1.64e-4)" "unprognostic (4.94e-3)" "unprognostic (1.21e-1)" "unprognostic (2.56e-1)" "unprognostic (1.79e-1)" HCRTR2 "ORXR2, OX2R, OXR2" ENSG00000137252 "Hypocretin receptor 2" O43614 6 55106460-55282617 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Excitatory neurons: 11.3;Inhibitory neurons: 17.6;Peritubular cells: 4.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "cervical cancer: 1.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA054516 Enhanced NA NA "Cluster 49: Hindbrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 65: Neurons - Synaptic function" 1 "HPA054516: AB_2682513" "unprognostic (4.86e-1)" "unprognostic (2.69e-2)" "unprognostic (1.86e-2)" "unprognostic (2.32e-1)" "unprognostic (7.45e-2)" "unprognostic (7.39e-2)" HDHD2 DKFZP564D1378 ENSG00000167220 "Haloacid dehalogenase like hydrolase domain containing 2" Q9H0R4 18 47107408-47150500 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 70.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040697, CAB045978, HPA059818" Approved Approved Vesicles NA NA 240000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 3: Non-specific - Unknown function" "Cluster 49: Hindbrain - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 39: Non-specific - Basic cellular processes" 1 Vesicles "CAB045978: AB_11124418, HPA040697: AB_2677084, HPA059818: AB_2684132" "unprognostic (3.22e-1)" "unprognostic (6.32e-2)" "unprognostic (9.95e-2)" "unprognostic (7.24e-2)" "unprognostic (1.11e-1)" "unprognostic (1.58e-1)" "unprognostic (3.11e-1)" "unprognostic (1.24e-1)" "unprognostic (2.10e-2)" "unprognostic (5.35e-3)" "unprognostic (1.82e-2)" "unprognostic (8.64e-3)" "prognostic favorable (3.52e-5)" "unprognostic (1.95e-1)" "unprognostic (1.61e-1)" "unprognostic (3.44e-1)" "unprognostic (1.17e-1)" HEATR5A "C14orf125, DKFZP434I1735, p200b" ENSG00000129493 "HEAT repeat containing 5A" Q86XA9 14 31291788-31420550 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 55.4;Oligodendrocyte precursor cells: 63.7;Oligodendrocytes: 89.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 121.1" "Lineage enriched" "Detected in all" 7 "granulocytes: 121.1" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049539 Uncertain NA NA "Cluster 41: Basophils - Unknown function" "Cluster 35: Non-specific - Mitochondria" "Cluster 49: Hindbrain - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 76: Oligodendrocyte precursor - Unknown function" "HPA049539: AB_2680809" "unprognostic (2.63e-1)" "unprognostic (2.24e-1)" "unprognostic (1.75e-3)" "unprognostic (2.16e-2)" "unprognostic (2.42e-1)" "unprognostic (5.47e-3)" "unprognostic (3.97e-2)" "unprognostic (9.37e-2)" "unprognostic (8.02e-2)" "unprognostic (1.70e-1)" "unprognostic (1.84e-1)" "unprognostic (1.04e-1)" "prognostic favorable (1.11e-6)" "unprognostic (1.00e-1)" "unprognostic (5.93e-2)" "unprognostic (2.83e-2)" "unprognostic (6.00e-2)" HMCN1 "ARMD1, FBLN6, FIBL-6, FIBL6" ENSG00000143341 "Hemicentin 1" Q96RW7 1 185734391-186190949 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell cycle, Cell division, Sensory transduction, Vision" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 19.7" "Cell type enhanced" "Detected in many" "Adipocytes: 37.7;Endothelial cells: 22.1;Fibroblasts: 22.5;Lymphatic endothelial cells: 35.5;Microglial cells: 42.9;Oocytes: 16.9;Salivary duct cells: 17.1;Schwann cells: 22.2" "Cancer enriched" "Detected in many" 6 "melanoma: 14.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 64.8;skin cancer: 50.9" "Breast - Fibroblasts, Colon - Enteric glia cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Fibroblasts" "Not detected" "Not detected" "Region enhanced" "Detected in many" "olfactory bulb: 13.2" "HPA008220, HPA051677" Uncertain Approved "Golgi apparatus,Cytosol" "Secreted to extracellular matrix" Other NA NA 9200000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 53: Fibroblasts - ECM organization" 1 "Golgi apparatus, Cytosol" "HPA008220: , HPA051677: AB_2681572" "unprognostic (1.90e-1)" "unprognostic (2.66e-1)" "unprognostic (8.00e-2)" "unprognostic (1.10e-1)" "unprognostic (7.77e-2)" "unprognostic (1.08e-1)" "unprognostic (1.96e-1)" "unprognostic (4.36e-2)" "unprognostic (2.20e-2)" "unprognostic (1.00e-1)" "unprognostic (1.15e-1)" "unprognostic (1.73e-1)" "prognostic unfavorable (3.59e-7)" "unprognostic (1.22e-2)" "unprognostic (5.17e-3)" "unprognostic (3.52e-1)" "unprognostic (2.00e-3)" HMGCS1 HMGCS ENSG00000112972 "3-hydroxy-3-methylglutaryl-CoA synthase 1" Q01581 5 43287470-43313512 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 379.0" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 419.4;Distal enterocytes: 279.6;Hepatocytes: 441.9;Suprabasal keratinocytes: 343.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032907, HPA036913, HPA036914" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" No No 470000 "Cluster 29: Non-specific - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 62: Hepatocytes - Metabolism" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB032907: AB_2118319, HPA036913: AB_2675380, HPA036914: AB_10671751" "unprognostic (1.31e-1)" "unprognostic (5.12e-3)" "unprognostic (6.82e-3)" "unprognostic (4.59e-2)" "unprognostic (8.39e-2)" "unprognostic (2.49e-2)" "unprognostic (1.03e-1)" "unprognostic (3.14e-2)" "unprognostic (1.27e-2)" "unprognostic (3.13e-1)" "unprognostic (6.40e-3)" "unprognostic (9.15e-2)" "prognostic favorable (3.87e-6)" "unprognostic (1.09e-1)" "unprognostic (9.22e-2)" "unprognostic (3.03e-2)" "unprognostic (2.37e-2)" HOXC4 "HOX3, HOX3E" ENSG00000198353 "Homeobox C4" P09017 12 54016931-54056030 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 26.2" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 10.6;Ciliated cells: 17.4;Secretory cells: 6.0;Squamous epithelial cells: 7.6" "Cancer enhanced" "Detected in many" "ovarian cancer: 12.4" "Region enhanced" "Detected in many" "pons: 34.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Lung - Fibroblast_2" "Region enriched" "Detected in single" 24 "pons and medulla: 9.4" "Group enriched" "Detected in some" 64 "medulla oblongata: 6.4;pons: 4.8;spinal cord: 7.8" HPA053910 Supported Nucleoplasm NA NA "Cluster 59: Fallopian tube - Tissue development" "Cluster 49: Hindbrain - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 42: Ciliated cells - Cilium assembly" 22 Nucleoplasm "HPA053910: AB_2682305" "unprognostic (2.78e-2)" "unprognostic (8.51e-2)" "unprognostic (2.96e-6)" "unprognostic (3.30e-2)" "unprognostic (6.27e-2)" "unprognostic (1.81e-2)" "unprognostic (1.24e-1)" "unprognostic (6.63e-3)" "unprognostic (6.42e-2)" "unprognostic (1.42e-1)" "unprognostic (8.83e-3)" "unprognostic (4.37e-2)" "unprognostic (7.81e-2)" "unprognostic (8.43e-2)" "unprognostic (1.50e-1)" "unprognostic (2.11e-4)" "unprognostic (9.82e-2)" HOXC5 "HOX3, HOX3D" ENSG00000172789 "Homeobox C5" Q00444 12 54033050-54035361 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 4.0" "Group enriched" "Detected in some" 4 "Basal squamous epithelial cells: 2.9;Gastric mucus-secreting cells: 1.2;Squamous epithelial cells: 1.6" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.7" "Group enriched" "Detected in some" 14 "medulla oblongata: 5.9;pons: 7.6;spinal cord: 4.2;white matter: 2.5" "Immune cell enhanced" "Detected in single" "gdT-cell: 3.0" "Lineage enriched" "Detected in single" 31 "T-cells: 3.0" "Low cancer specificity" "Detected in many" "Lung - Fibroblast_2" "Region enriched" "Detected in single" 46 "pons and medulla: 4.6" "Group enriched" "Detected in some" 5 "medulla oblongata: 2.0;spinal cord: 2.8" HPA026794 Uncertain Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 59: Fallopian tube - Tissue development" "Cluster 49: Hindbrain - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 49: Non-specific - Transcription" 9 Nucleoplasm "Cell Junctions" "HPA026794: AB_10612118" "unprognostic (1.57e-1)" "unprognostic (7.73e-3)" "unprognostic (1.70e-2)" "unprognostic (2.49e-1)" "unprognostic (1.16e-3)" "unprognostic (2.87e-3)" "unprognostic (6.89e-2)" "unprognostic (9.53e-3)" "unprognostic (1.86e-2)" "unprognostic (2.69e-2)" "unprognostic (2.01e-3)" "unprognostic (1.17e-2)" "unprognostic (7.53e-3)" "unprognostic (2.19e-3)" "unprognostic (1.08e-2)" HOXC6 "HOX3, HOX3C" ENSG00000197757 "Homeobox C6" P09630 12 53990624-54030823 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 26.2;ovary: 25.4" "Cell type enhanced" "Detected in some" "Distal tubular cells: 12.3;Fibroblasts: 12.3;Leydig cells: 20.6;Melanocytes: 15.5;Ovarian stromal cells: 27.1;Peritubular cells: 14.3;Smooth muscle cells: 13.1;Spermatocytes: 39.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 11 "medulla oblongata: 6.9;pons: 9.4;spinal cord: 6.7;white matter: 3.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 41.4" "Lung - Fibroblast_2" "Region enriched" "Detected in single" 15 "pons and medulla: 1.4" "Region enriched" "Detected in some" 15 "spinal cord: 14.9" HPA054981 Supported Nucleoplasm,Cytosol No No "Cluster 62: Connective tissue - ECM organization" "Cluster 49: Hindbrain - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 6: Ovarian stromal cells - Transcription" Nucleoplasm Cytosol "HPA054981: AB_2682662" "unprognostic (3.54e-2)" "unprognostic (9.20e-2)" "unprognostic (1.68e-6)" "unprognostic (3.92e-2)" "unprognostic (1.10e-3)" "unprognostic (5.01e-4)" "unprognostic (5.52e-3)" "unprognostic (3.32e-3)" "unprognostic (2.81e-1)" "unprognostic (6.26e-2)" "unprognostic (8.82e-2)" "unprognostic (3.70e-3)" "prognostic unfavorable (3.55e-6)" "unprognostic (8.63e-2)" "unprognostic (5.76e-2)" "unprognostic (1.40e-2)" "unprognostic (4.71e-2)" HPS1 "BLOC3S1, HPS" ENSG00000107521 "HPS1 biogenesis of lysosomal organelles complex 3 subunit 1" Q92902 10 98410939-98446963 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Guanine-nucleotide releasing factor" "Albinism, Disease variant, Hermansky-Pudlak syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061260 Approved NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 1: Erythroid cells - Oxygen transport" 1 "HPA061260: AB_2684459" "unprognostic (1.31e-1)" "prognostic favorable (3.37e-5)" "unprognostic (8.95e-2)" "prognostic favorable (2.93e-5)" "prognostic unfavorable (6.54e-4)" "unprognostic (2.19e-1)" "unprognostic (9.38e-3)" "prognostic favorable (1.26e-4)" "unprognostic (2.39e-1)" "unprognostic (2.44e-3)" "unprognostic (5.64e-3)" "unprognostic (2.24e-1)" "unprognostic (1.76e-1)" "unprognostic (4.74e-2)" "unprognostic (1.84e-1)" "unprognostic (3.06e-2)" "unprognostic (8.30e-3)" HRNR "FLG3, S100A16, S100a18" ENSG00000197915 Hornerin Q86YZ3 1 152212076-152224193 "Plasma proteins, Predicted intracellular proteins" Keratinization "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Horizontal cells: 1.3;Pancreatic endocrine cells: 1.7;Rod photoreceptor cells: 4.1" "Cancer enriched" "Detected in single" 4 "melanoma: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 3.0" "Not detected" "Not detected" HPA031469 Uncertain Uncertain Mitochondria No No 180000000 "Cluster 49: Hindbrain - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 66: Photoreceptor cells - Visual perception" Mitochondria "HPA031469: AB_10603771" "unprognostic (1.34e-1)" "unprognostic (4.51e-2)" "unprognostic (3.01e-2)" "unprognostic (8.72e-4)" "unprognostic (1.61e-2)" "unprognostic (1.45e-1)" "unprognostic (2.11e-1)" "unprognostic (1.79e-1)" "unprognostic (6.09e-2)" "unprognostic (3.38e-2)" "unprognostic (1.87e-2)" "unprognostic (1.59e-2)" "unprognostic (1.65e-2)" "unprognostic (2.49e-2)" "unprognostic (1.71e-1)" "unprognostic (2.07e-1)" "unprognostic (3.64e-2)" HSD17B7 "PRAP, SDR37C1" ENSG00000132196 "Hydroxysteroid 17-beta dehydrogenase 7" P56937 1 162790702-162812823 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 32.8" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 51.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047496 Approved NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 53: Non-specific - Glycosylation" "Cluster 49: Hindbrain - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 62: Hepatocytes - Metabolism" "HPA047496: AB_2680068" "unprognostic (2.93e-1)" "unprognostic (1.36e-2)" "unprognostic (6.03e-2)" "unprognostic (1.12e-1)" "unprognostic (2.34e-1)" "unprognostic (1.63e-3)" "unprognostic (2.57e-1)" "unprognostic (2.51e-2)" "unprognostic (1.36e-1)" "unprognostic (1.38e-1)" "unprognostic (1.94e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (8.47e-5)" "unprognostic (6.25e-2)" "unprognostic (1.90e-1)" "unprognostic (6.35e-2)" "unprognostic (3.17e-2)" HSPBAP1 "FLJ22623, PASS1" ENSG00000169087 "HSPB1 associated protein 1" Q96EW2 3 122739999-122793831 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 50.3;Microglial cells: 50.1;Syncytiotrophoblasts: 57.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044930 Approved Approved Mitochondria NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 4: Testis - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 65: Neurons - Synaptic function" 3 Mitochondria "HPA044930: AB_10961122" "unprognostic (3.40e-3)" "unprognostic (1.22e-2)" "unprognostic (2.98e-2)" "unprognostic (6.70e-3)" "unprognostic (3.40e-3)" "unprognostic (3.40e-2)" "unprognostic (8.61e-4)" "unprognostic (2.68e-2)" "unprognostic (6.95e-2)" "unprognostic (3.35e-2)" "unprognostic (2.36e-1)" "unprognostic (8.91e-2)" "unprognostic (1.24e-3)" "unprognostic (4.29e-1)" "unprognostic (1.33e-1)" "unprognostic (3.34e-1)" "unprognostic (4.12e-3)" IDI1 ENSG00000067064 "Isopentenyl-diphosphate delta isomerase 1" Q13907 10 1039152-1049119 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Isoprene biosynthesis, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039169 Approved NA NA 28000 "Cluster 35: Neutrophils - Protein binding" "Cluster 56: Non-specific - Unknown function" "Cluster 49: Hindbrain - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 62: Hepatocytes - Metabolism" "HPA039169: AB_10674280" "unprognostic (1.61e-2)" "unprognostic (2.59e-2)" "unprognostic (4.58e-2)" "unprognostic (1.97e-1)" "unprognostic (5.72e-3)" "unprognostic (1.27e-1)" "unprognostic (1.76e-2)" "unprognostic (1.97e-1)" "unprognostic (3.72e-2)" "unprognostic (3.88e-2)" "unprognostic (2.59e-1)" "unprognostic (2.26e-1)" "prognostic favorable (1.46e-4)" "unprognostic (9.63e-2)" "unprognostic (2.01e-2)" "unprognostic (2.19e-3)" "unprognostic (2.61e-2)" IGFBP1 "AFBP, hIGFBP-1, IBP1, IGF-BP25, PP12" ENSG00000146678 "Insulin like growth factor binding protein 1" P08833 7 45888360-45893660 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 1163.6" "Cell type enriched" "Detected in some" 9 "Hepatocytes: 900.0" "Cancer enriched" "Detected in many" 29 "liver cancer: 385.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 38.2;liver cancer: 75.4;ovarian cancer: 50.4" "Breast - Breast glandular cells (progenitors), Kidney - Intercalated cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB004445, HPA046972, HPA050640" Enhanced Approved "Golgi apparatus" "Secreted to blood" Other NA NA 28100000 25000000 "Cluster 83: Liver - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 43: Hepatocytes - Metabolism" 3 "Golgi apparatus" "CAB004445: AB_627782, HPA046972: AB_2679884, HPA050640: AB_2681197" "unprognostic (8.66e-3)" "unprognostic (1.45e-1)" "unprognostic (9.41e-2)" "unprognostic (7.80e-2)" "unprognostic (7.04e-2)" "unprognostic (2.93e-1)" "unprognostic (1.01e-1)" "prognostic unfavorable (1.03e-4)" "unprognostic (1.89e-2)" "unprognostic (2.09e-3)" "unprognostic (8.95e-2)" "prognostic unfavorable (6.90e-11)" "prognostic unfavorable (6.64e-4)" "unprognostic (7.20e-2)" "unprognostic (7.98e-2)" "unprognostic (3.43e-1)" IGFBP3 "BP-53, IBP3" ENSG00000146674 "Insulin like growth factor binding protein 3" P17936 7 45912245-45921874 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Growth factor binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 693.4;placenta: 1799.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 815.8;Club cells: 408.7;Extravillous trophoblasts: 2449.9;Ionocytes: 425.9" "Cancer enhanced" "Detected in all" "renal cancer: 377.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 48.9" "Lineage enriched" "Detected in many" 5 "dendritic cells: 48.9" "Cancer enriched" "Detected in all" 5 "Kidney cancer: 3358.0" "Liver - Hepatic stellate cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB010360 Uncertain Vesicles "Secreted to blood" Other NA NA 3250000000 3600000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 58: Placenta - Pregnancy" "Cluster 49: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Connective tissue cells - ECM organization" 5 Vesicles "CAB010360: AB_2233528" "unprognostic (4.46e-3)" "unprognostic (4.84e-2)" "prognostic unfavorable (1.08e-4)" "unprognostic (2.30e-1)" "unprognostic (1.15e-1)" "unprognostic (6.54e-2)" "prognostic unfavorable (1.64e-4)" "unprognostic (8.14e-3)" "unprognostic (3.31e-2)" "unprognostic (2.03e-1)" "unprognostic (9.67e-3)" "unprognostic (2.80e-1)" "prognostic unfavorable (5.07e-7)" "unprognostic (2.36e-2)" "unprognostic (4.14e-2)" "unprognostic (2.37e-3)" "unprognostic (2.63e-1)" IGHD2OR15-2A "IGHD2/OR15-2A, IGHD2OR152A" ENSG00000282599 "Immunoglobulin heavy diversity 2/OR15-2A (non-functional)" 15 20008402-20008432 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Gallbladder cancer: 1.5" NA NA "Cluster 49: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" IGHD2OR15-2B "IGHD2/OR15-2B, IGHD2OR152B" ENSG00000282268 "Immunoglobulin heavy diversity 2/OR15-2B (non-functional)" 15 21015048-21015078 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Gallbladder cancer: 1.5" NA NA "Cluster 49: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" IGHD3OR15-3A "IGHD3/OR15-3A, IGHD3OR153A" ENSG00000282520 "Immunoglobulin heavy diversity 3/OR15-3A (non-functional)" 15 20005905-20005935 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 49: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" IGHD3OR15-3B "IGHD3/OR15-3B, IGHD3OR153B" ENSG00000282089 "Immunoglobulin heavy diversity 3/OR15-3B (non-functional)" 15 21012559-21012589 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 49: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" IGLON5 LOC402665 ENSG00000142549 "IgLON family member 5" A6NGN9 19 51311644-51330891 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 64.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 17.6;Horizontal cells: 69.2;Inhibitory neurons: 16.8;Spermatogonia: 9.5" "Group enriched" "Detected in many" 5 "glioma: 9.2;ovarian cancer: 3.5;testis cancer: 12.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Neuroblastoma: 15.2;testis cancer: 7.2" "Colon - Colon enteroendocrine cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041994 Approved "Secreted in brain" "No annotated function" NA NA 15000 "Cluster 65: Cerebellum - Nervous system development" "Cluster 49: Hindbrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "HPA041994: AB_10794641" "unprognostic (2.09e-1)" "unprognostic (5.76e-2)" "unprognostic (1.80e-2)" "unprognostic (8.87e-3)" "unprognostic (2.33e-1)" "unprognostic (2.66e-1)" "unprognostic (3.47e-4)" "unprognostic (6.38e-5)" "unprognostic (4.54e-2)" "unprognostic (7.89e-3)" "unprognostic (1.59e-1)" "unprognostic (1.81e-1)" "prognostic unfavorable (5.62e-7)" "unprognostic (1.77e-2)" "unprognostic (9.28e-2)" "unprognostic (1.36e-2)" "unprognostic (1.86e-3)" IGLV6-57 ENSG00000211640 "Immunoglobulin lambda variable 6-57" P01721 22 22195799-22196276 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1752.9;urinary bladder: 652.7" "Cell type enriched" "Detected in some" 150 "Plasma cells: 7810.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 11 "memory B-cell: 355.6;naive B-cell: 294.1" "Lineage enriched" "Detected in many" 13 "B-cells: 355.6" "Cancer enriched" "Detected in some" 6 "lymphoma: 204.4" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA028862 Supported "Immunoglobulin genes" Immunity NA NA 1900000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 49: Hindbrain - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 23: Plasma cells - Humoral immune response" "HPA028862: " "prognostic favorable (1.92e-6)" "unprognostic (5.73e-2)" "unprognostic (2.59e-2)" "unprognostic (2.11e-2)" "unprognostic (1.14e-2)" "prognostic favorable (1.36e-5)" "unprognostic (1.87e-2)" "unprognostic (2.56e-1)" "unprognostic (6.55e-2)" "unprognostic (3.87e-2)" "unprognostic (1.52e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (2.30e-6)" "unprognostic (2.82e-1)" "unprognostic (1.23e-1)" "unprognostic (1.52e-1)" "unprognostic (1.11e-1)" INSIG1 "CL-6, MGC1405" ENSG00000186480 "Insulin induced gene 1" O15503 7 155297776-155310235 "Plasma proteins, Predicted membrane proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 547.3" "Cell type enriched" "Detected in all" 7 "Langerhans cells: 5100.7" "Cancer enriched" "Detected in all" 5 "liver cancer: 142.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "intermediate monocyte: 273.2;non-classical monocyte: 503.5" "Lineage enriched" "Detected in all" 6 "monocytes: 503.5" "Cancer enhanced" "Detected in all" "Myeloma: 314.2" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071524 Uncertain Vesicles NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 83: Liver - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 28: Dendritic cells - Antigen presentation" 2 Vesicles "HPA071524: " "unprognostic (8.11e-2)" "unprognostic (3.22e-1)" "unprognostic (2.91e-1)" "unprognostic (1.47e-1)" "unprognostic (9.23e-2)" "unprognostic (3.83e-2)" "unprognostic (2.05e-2)" "unprognostic (3.06e-1)" "unprognostic (1.60e-2)" "unprognostic (1.52e-1)" "unprognostic (4.64e-2)" "unprognostic (2.12e-1)" "unprognostic (1.26e-1)" "unprognostic (1.85e-1)" "unprognostic (1.91e-1)" "prognostic unfavorable (9.62e-4)" "unprognostic (4.97e-2)" INSRR IRR ENSG00000027644 "Insulin receptor related receptor" P14616 1 156840063-156859117 "Enzymes, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 3.7;testis: 1.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.2;Collecting duct cells: 1.9;Horizontal cells: 1.9;Late spermatids: 1.6;Sertoli cells: 2.7;Spermatocytes: 6.2;Spermatogonia: 1.8" "Not detected" "Not detected" "Region enhanced" "Detected in many" "pons: 31.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 8 "Neuroblastoma: 7.5" "Kidney - Intercalated cells, Skeletal muscle - Fibroblasts" "Not detected" "Not detected" "Not detected" "Not detected" HPA025285 Uncertain NA NA "Cluster 78: Testis - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 79: Spermatocytes & Spermatogonia - Spermatogenesis" 2 "HPA025285: AB_1851814" "unprognostic (1.19e-1)" "unprognostic (7.69e-2)" "unprognostic (2.42e-2)" "unprognostic (6.76e-4)" "unprognostic (1.51e-1)" "unprognostic (9.07e-3)" "unprognostic (5.57e-2)" "unprognostic (1.75e-1)" "unprognostic (6.17e-2)" "unprognostic (5.57e-2)" "unprognostic (2.20e-2)" "unprognostic (7.00e-2)" "unprognostic (4.22e-5)" "unprognostic (2.82e-1)" "unprognostic (9.55e-2)" "unprognostic (2.75e-3)" "unprognostic (3.66e-2)" IRX1 IRX-5 ENSG00000170549 "Iroquois homeobox 1" P78414 5 3595832-3601403 "Plasma proteins, Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 15.7;kidney: 28.1;salivary gland: 17.3" "Cell type enhanced" "Detected in some" "Breast glandular cells: 56.4;Breast myoepithelial cells: 92.3;Mucus glandular cells: 18.9;Salivary duct cells: 27.6" "Group enriched" "Detected in many" 6 "breast cancer: 5.6;glioma: 6.6;testis cancer: 15.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 5.1;Leukemia: 8.3" "Pancreas - Alpha cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA043160 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 49: Hindbrain - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 17: Breast glandular cells - Lactation" "Golgi apparatus" Nucleoplasm "HPA043160: AB_10794771" "unprognostic (1.52e-2)" "unprognostic (1.26e-2)" "unprognostic (2.27e-1)" "unprognostic (3.73e-2)" "unprognostic (4.30e-3)" "unprognostic (2.70e-1)" "unprognostic (2.02e-2)" "unprognostic (2.03e-2)" "unprognostic (9.78e-4)" "unprognostic (5.11e-2)" "unprognostic (2.78e-2)" "unprognostic (3.58e-2)" IRX2 ENSG00000170561 "Iroquois homeobox 2" Q9BZI1 5 2745845-2751677 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 23.3;kidney: 20.9;salivary gland: 29.7;skin 1: 27.4" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 191.4;Alveolar cells type 2: 134.3;Basal keratinocytes: 130.8;Breast glandular cells: 150.2;Breast myoepithelial cells: 175.5;Mucus glandular cells: 64.6;Salivary duct cells: 114.5;Suprabasal keratinocytes: 80.6" "Cancer enhanced" "Detected in many" "breast cancer: 14.8" "Region enhanced" "Detected in many" "pons: 46.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 33.5" "Pancreas - Alpha cells, Stomach - Chief cells, Testis - Spermatogonia" "Group enriched" "Detected in many" 5 "midbrain: 26.5;pons and medulla: 20.9;thalamus: 11.2" "Region enhanced" "Detected in many" "pons: 8.0" "HPA050895, HPA054669" Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 49: Hindbrain - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 17: Breast glandular cells - Lactation" 2 "Nucleoplasm, Nucleoli" "HPA050895: AB_2616458, HPA054669: AB_2682566" "unprognostic (9.79e-2)" "unprognostic (1.93e-2)" "unprognostic (8.48e-2)" "unprognostic (5.50e-3)" "unprognostic (8.12e-2)" "unprognostic (3.07e-3)" "unprognostic (1.33e-1)" "unprognostic (7.47e-3)" "unprognostic (1.95e-1)" "unprognostic (3.07e-1)" "prognostic favorable (8.84e-4)" "unprognostic (2.62e-2)" "unprognostic (3.98e-7)" "unprognostic (4.40e-2)" "unprognostic (2.49e-1)" "unprognostic (3.67e-2)" "unprognostic (8.97e-2)" KANK4 "ANKRD38, KIAA0172" ENSG00000132854 "KN motif and ankyrin repeat domains 4" Q5T7N3 1 62236165-62319434 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 10.4;brain: 9.8;pancreas: 14.7;placenta: 10.4" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 15.4;Cytotrophoblasts: 54.0;Extravillous trophoblasts: 38.3;Oligodendrocytes: 31.9;Schwann cells: 30.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 18.8;testis cancer: 25.0" "Liver - Hepatocytes, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA014030 Uncertain Uncertain Microtubules,Cytosol NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 49: Hindbrain - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 24: Cytotrophoblasts - Mitochondria" 5 Cytosol Microtubules "HPA014030: AB_2128155" "unprognostic (1.66e-2)" "unprognostic (1.90e-3)" "unprognostic (2.65e-2)" "unprognostic (1.11e-3)" "unprognostic (2.27e-2)" "unprognostic (1.48e-2)" "unprognostic (6.31e-2)" "unprognostic (1.66e-2)" "unprognostic (3.58e-2)" "unprognostic (1.54e-1)" "unprognostic (3.85e-3)" "unprognostic (1.30e-1)" "unprognostic (4.08e-3)" "unprognostic (9.06e-2)" "unprognostic (1.97e-1)" "unprognostic (3.31e-2)" "unprognostic (7.74e-6)" KCNH2 "erg1, HERG, Kv11.1, LQT2" ENSG00000055118 "Potassium voltage-gated channel subfamily H member 2" Q12809 7 150944961-150978321 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Deafness, Disease variant, FDA approved drug targets, Long QT syndrome, Short QT syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 40.8;pituitary gland: 42.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 209.8;Cardiomyocytes: 80.3;Erythroid cells: 116.1;granulocytes: 43.3;Horizontal cells: 57.3;Sertoli cells: 65.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Leukemia: 23.5;Neuroblastoma: 41.8" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Lung - Fibroblast_1, Pancreas - Alpha cells, Pancreas - Beta cells, Prostate - Smooth muscle cells, Skin - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 28: Neuronal - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 1: Erythroid cells - Oxygen transport" "unprognostic (2.22e-1)" "unprognostic (1.75e-2)" "unprognostic (1.06e-2)" "prognostic unfavorable (6.06e-5)" "unprognostic (9.79e-3)" "unprognostic (1.95e-2)" "unprognostic (3.40e-2)" "unprognostic (3.84e-2)" "unprognostic (3.53e-2)" "unprognostic (3.52e-1)" "prognostic favorable (5.61e-4)" "unprognostic (6.08e-2)" "unprognostic (2.26e-2)" "unprognostic (4.90e-2)" "unprognostic (2.83e-1)" "unprognostic (6.24e-2)" "unprognostic (3.02e-2)" KCNH6 "erg2, HERG2, Kv11.2" ENSG00000173826 "Potassium voltage-gated channel subfamily H member 6" Q9H252 17 63523334-63548977 "FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.7;kidney: 6.8;pituitary gland: 5.2;prostate: 3.8;retina: 4.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 42.1;Cone photoreceptor cells: 11.9;Enteroendocrine cells: 27.3;Horizontal cells: 11.3;Prostatic glandular cells: 24.5;Proximal enterocytes: 40.9" "Cancer enhanced" "Detected in some" "prostate cancer: 5.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 6.2;lung cancer: 9.7;prostate cancer: 5.3" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Pancreas - Alpha cells, Prostate - Prostate glandular cells, Stomach - Gastric enteroendocrine cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "medulla oblongata: 1.4;olfactory bulb: 3.2;spinal cord: 3.2" HPA061704 Approved NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 49: Hindbrain - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 22: Proximal enterocytes - Digestion" "HPA061704: " "unprognostic (8.00e-2)" "unprognostic (1.80e-1)" "unprognostic (5.46e-2)" "unprognostic (5.68e-2)" "unprognostic (5.98e-5)" "unprognostic (3.39e-1)" "unprognostic (1.15e-1)" "unprognostic (3.03e-1)" "unprognostic (1.28e-2)" "unprognostic (3.25e-1)" "unprognostic (1.74e-3)" "unprognostic (3.95e-1)" "unprognostic (1.19e-1)" "unprognostic (9.80e-2)" "unprognostic (3.66e-1)" "unprognostic (8.05e-2)" "unprognostic (9.15e-2)" KCNK3 "K2p3.1, TASK, TASK-1, TASK1" ENSG00000171303 "Potassium two pore domain channel subfamily K member 3" O14649 2 26692722-26733420 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "adrenal gland: 170.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 67.1;Collecting duct cells: 103.1;Enteroendocrine cells: 28.1;Exocrine glandular cells: 78.8;Smooth muscle cells: 30.4" "Cancer enhanced" "Detected in many" "renal cancer: 9.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 11.5;thyroid cancer: 10.3" "Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 48: Smooth muscle cells - Signal transduction" 1 "unprognostic (4.16e-3)" "unprognostic (7.13e-2)" "unprognostic (1.04e-1)" "unprognostic (1.67e-4)" "unprognostic (2.08e-1)" "unprognostic (2.91e-1)" "unprognostic (5.01e-2)" "unprognostic (2.16e-1)" "unprognostic (3.31e-1)" "unprognostic (5.48e-2)" "unprognostic (3.77e-2)" "unprognostic (1.48e-2)" "prognostic unfavorable (2.37e-7)" "unprognostic (3.09e-2)" "unprognostic (7.45e-2)" "unprognostic (1.44e-2)" "unprognostic (9.24e-3)" KCNMB1 hslo-beta ENSG00000145936 "Potassium calcium-activated channel subfamily M regulatory beta subunit 1" Q16558 5 170374671-170389634 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 57.2;intestine: 72.5;smooth muscle: 51.1" "Cell type enriched" "Detected in many" 5 "Peritubular cells: 354.8" "Cancer enhanced" "Detected in many" "prostate cancer: 6.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 5.7;monocytes: 5.9" "Cancer enhanced" "Detected in some" "Leukemia: 3.2" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Smooth muscle cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 49: Hindbrain - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 32: Smooth muscle cells - Muscle contraction" "unprognostic (2.06e-2)" "unprognostic (2.70e-4)" "unprognostic (1.69e-2)" "unprognostic (1.27e-1)" "unprognostic (3.37e-2)" "unprognostic (8.88e-2)" "unprognostic (1.61e-2)" "unprognostic (3.46e-1)" "unprognostic (2.28e-1)" "unprognostic (4.68e-2)" "unprognostic (5.37e-1)" "unprognostic (1.00e-1)" "prognostic unfavorable (4.13e-6)" "unprognostic (1.08e-1)" "unprognostic (2.49e-1)" "unprognostic (4.31e-2)" "unprognostic (1.04e-2)" KCNS3 Kv9.3 ENSG00000170745 "Potassium voltage-gated channel modifier subfamily S member 3" Q9BQ31 2 17877847-18361616 "Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 83.0;tongue: 43.8" "Cell type enhanced" "Detected in many" "Skeletal myocytes: 32.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014864 Approved Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 50: Connective tissue cells - ECM organization" Cytosol "Golgi apparatus, Plasma membrane" "HPA014864: AB_1852155" "unprognostic (5.62e-2)" "unprognostic (4.27e-3)" "unprognostic (6.87e-2)" "unprognostic (1.68e-1)" "unprognostic (3.19e-1)" "unprognostic (1.64e-2)" "unprognostic (3.30e-1)" "unprognostic (9.47e-3)" "unprognostic (9.06e-2)" "unprognostic (8.45e-2)" "unprognostic (5.82e-2)" "unprognostic (1.36e-1)" "prognostic unfavorable (1.53e-4)" "unprognostic (1.64e-2)" "unprognostic (2.34e-1)" "unprognostic (1.67e-1)" "unprognostic (4.71e-2)" KLK10 "NES1, PRSSL1" ENSG00000129451 "Kallikrein related peptidase 10" O43240 19 51012739-51020175 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Cell cycle" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 108.7;esophagus: 400.9;vagina: 184.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 75.8;Basal respiratory cells: 62.0;Club cells: 92.0;Ionocytes: 71.8;Mucus glandular cells: 62.4;Secretory cells: 79.4;Suprabasal keratinocytes: 140.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 97.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 80.0;pancreatic cancer: 79.5" "Adipose visceral - Mesothelial cells, Prostate - Prostate basal glandular cells" "Region enriched" "Detected in single" 4 "hippocampal formation: 1.6" "Not detected" "Not detected" "Secreted in other tissues" Enzyme NA NA 2500000 "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" "prognostic favorable (8.32e-4)" "unprognostic (6.06e-2)" "unprognostic (1.73e-1)" "unprognostic (4.26e-3)" "unprognostic (3.81e-2)" "unprognostic (1.80e-1)" "unprognostic (1.51e-2)" "unprognostic (2.10e-2)" "unprognostic (3.94e-1)" "unprognostic (3.38e-2)" "prognostic unfavorable (6.46e-5)" "unprognostic (2.71e-2)" "unprognostic (2.46e-6)" "unprognostic (9.34e-2)" "unprognostic (7.81e-2)" "unprognostic (2.66e-3)" "unprognostic (1.52e-2)" KLK4 "EMSP, EMSP1, KLK-L1, PRSS17, PSTS" ENSG00000167749 "Kallikrein related peptidase 4" Q9Y5K2 19 50906351-50911395 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Hydrolase, Protease, Serine protease" "Amelogenesis imperfecta, Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 34 "prostate: 277.9" "Cell type enriched" "Detected in some" 91 "Prostatic glandular cells: 606.0" "Cancer enriched" "Detected in many" 55 "prostate cancer: 463.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 16 "prostate cancer: 107.3" "Prostate - Prostate glandular cells" "Not detected" "Not detected" "Region enhanced" "Detected in many" "spinal cord: 5.9" HPA051839 Enhanced "Secreted in male reproductive system" Enzyme NA NA "Cluster 64: Neuronal - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 40: Prostatic glandular cells - Transcription" 2 "HPA051839: AB_2681632" "unprognostic (3.58e-2)" "unprognostic (2.26e-1)" "unprognostic (1.23e-3)" "unprognostic (1.66e-3)" "unprognostic (3.11e-2)" "unprognostic (4.35e-1)" "unprognostic (3.18e-1)" "unprognostic (6.66e-2)" "unprognostic (9.69e-2)" "unprognostic (8.23e-3)" "unprognostic (1.26e-1)" "unprognostic (1.07e-1)" "unprognostic (4.20e-3)" "unprognostic (3.27e-3)" "unprognostic (2.21e-2)" "unprognostic (1.64e-2)" "unprognostic (1.34e-1)" KRT18 ENSG00000111057 "Keratin 18" P05783 12 52948871-52952906 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Host-virus interaction" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 3815.2;Distal enterocytes: 4172.9;Ductal cells: 5450.8;Extravillous trophoblasts: 6192.8;Syncytiotrophoblasts: 8413.7" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 5 "choroid plexus: 72.5;hypothalamus: 28.1;medulla oblongata: 35.3;pons: 63.2" "Immune cell enriched" "Detected in many" 7 "basophil: 76.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 76.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 15.6" "CAB000008, CAB000030, HPA001605" Enhanced Supported Cytosol NA NA 140000000 "Cluster 46: Basophils - Proteolysis" "Cluster 45: Intestine - Digestion" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 26 Cytosol "CAB000008: , CAB000030: , HPA001605: AB_2666381" "unprognostic (1.98e-1)" "unprognostic (1.03e-1)" "unprognostic (3.31e-1)" "unprognostic (1.63e-2)" "unprognostic (1.25e-1)" "unprognostic (7.26e-3)" "unprognostic (4.09e-3)" "prognostic unfavorable (5.06e-4)" "unprognostic (8.81e-2)" "unprognostic (4.17e-1)" "prognostic unfavorable (1.78e-4)" "unprognostic (3.05e-1)" "unprognostic (1.04e-1)" "unprognostic (1.27e-1)" "unprognostic (2.19e-1)" "unprognostic (1.11e-2)" "unprognostic (1.13e-2)" LDLR LDLCQ2 ENSG00000130164 "Low density lipoprotein receptor" P01130 19 11089462-11133820 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol metabolism, Endocytosis, Host-virus interaction, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Host cell receptor for virus entry, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 108.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 445.1;Distal enterocytes: 298.1;Suprabasal keratinocytes: 286.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 9 "basophil: 46.2" "Lineage enriched" "Detected in many" 9 "granulocytes: 46.2" "Low cancer specificity" "Detected in all" "Colon - Neutrophils, Heart muscle - Endothelial cells, Testis - Leydig cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009647, HPA013159" Approved NA NA 23000000 "Cluster 41: Basophils - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 72: Alveolar cells - Lung function" 7 "HPA009647: AB_1079243, HPA013159: AB_1852775" "unprognostic (4.39e-1)" "unprognostic (1.93e-3)" "unprognostic (2.52e-1)" "unprognostic (2.76e-1)" "unprognostic (4.03e-2)" "unprognostic (1.17e-1)" "unprognostic (6.71e-2)" "unprognostic (4.26e-2)" "unprognostic (3.73e-1)" "unprognostic (1.47e-2)" "prognostic unfavorable (6.60e-5)" "unprognostic (1.19e-1)" "prognostic unfavorable (5.92e-4)" "unprognostic (1.62e-1)" "unprognostic (2.78e-2)" "unprognostic (9.83e-2)" "prognostic unfavorable (3.43e-4)" LEMD1 "CT50, LEMP-1" ENSG00000186007 "LEM domain containing 1" Q68G75 1 205381378-205455954 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "epididymis: 14.5;testis: 53.6" "Cell type enriched" "Detected in many" 6 "Late spermatids: 4290.5" "Cancer enhanced" "Detected in many" "ovarian cancer: 10.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 18.4" "Lung - Alveolar cells type 2, Prostate - Urothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 1.1" HPA076708 Approved "Plasma membrane" NA NA "Cluster 63: Testis - Spermatid development" "Cluster 49: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 63: Late spermatids - Spermatogenesis" 12 "Plasma membrane" "HPA076708: " "unprognostic (1.78e-1)" "unprognostic (2.00e-1)" "unprognostic (1.88e-2)" "unprognostic (4.20e-3)" "unprognostic (7.27e-2)" "unprognostic (1.48e-1)" "unprognostic (2.72e-2)" "unprognostic (1.01e-1)" "prognostic favorable (1.26e-4)" "prognostic unfavorable (1.70e-4)" "unprognostic (3.31e-1)" "unprognostic (5.66e-6)" "unprognostic (2.49e-2)" "unprognostic (2.07e-1)" "unprognostic (1.66e-1)" "unprognostic (1.38e-2)" LOXL2 "LOR, WS9-14" ENSG00000134013 "Lysyl oxidase like 2" Q9Y4K0 8 23296897-23425328 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Transcription, Transcription regulation" "Chromatin regulator, Oxidoreductase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 39.7" "Cell type enriched" "Detected in many" 6 "Oocytes: 241.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Kidney cancer: 665.7" "Breast - Adipocytes (Breast), Skeletal muscle - Fibroblasts, Thyroid - Endothelial cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" "CAB025848, HPA036257, HPA056542" Approved Enhanced Nucleoplasm "Secreted to extracellular matrix" Transcription NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 49: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Connective tissue cells - ECM organization" 4 Nucleoplasm "CAB025848: , HPA036257: AB_2675025, HPA056542: AB_2683168" "unprognostic (9.48e-2)" "prognostic unfavorable (9.83e-6)" "unprognostic (2.03e-1)" "unprognostic (2.81e-2)" "prognostic unfavorable (1.24e-4)" "unprognostic (5.55e-2)" "unprognostic (1.42e-2)" "prognostic unfavorable (1.46e-7)" "unprognostic (2.91e-2)" "unprognostic (3.63e-3)" "prognostic unfavorable (9.05e-4)" "unprognostic (1.25e-1)" "prognostic unfavorable (2.91e-7)" "unprognostic (1.51e-2)" "unprognostic (7.07e-2)" "unprognostic (4.93e-2)" "unprognostic (3.68e-3)" LPIN2 KIAA0249 ENSG00000101577 "Lipin 2" Q92539 18 2885296-3013144 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Transcription, Transcription regulation" Hydrolase "Congenital dyserythropoietic anemia, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 146.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 156.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 6 "granulocytes: 32.0;NK-cells: 13.3;T-cells: 12.0" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015223, HPA017857, HPA030550" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" Yes No "Cluster 35: Neutrophils - Protein binding" "Cluster 83: Liver - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" Cytosol "Plasma membrane, Actin filaments" "CAB015223: , HPA017857: AB_1852904, HPA030550: AB_2673519" "unprognostic (7.03e-2)" "unprognostic (1.05e-1)" "unprognostic (2.88e-1)" "unprognostic (1.51e-3)" "unprognostic (1.20e-1)" "prognostic favorable (8.01e-4)" "unprognostic (9.85e-3)" "unprognostic (1.89e-2)" "unprognostic (1.03e-2)" "unprognostic (3.44e-3)" "unprognostic (3.19e-1)" "unprognostic (1.94e-1)" "unprognostic (3.15e-3)" "unprognostic (4.66e-2)" "unprognostic (2.21e-1)" "unprognostic (2.49e-1)" "unprognostic (7.11e-2)" LRRN1 FIGLER3 ENSG00000175928 "Leucine rich repeat neuronal 1" Q6UXK5 3 3799431-3849834 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.2" "Cell type enriched" "Detected in many" 6 "Oligodendrocyte precursor cells: 392.4" "Cancer enhanced" "Detected in many" "glioma: 20.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 12 "testis cancer: 96.2" "Adipose visceral - Mesothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011071 Enhanced NA NA 2400000 "Cluster 33: Brain - Neuronal signaling" "Cluster 49: Hindbrain - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 76: Oligodendrocyte precursor - Unknown function" 1 "HPA011071: AB_1853355" "unprognostic (1.27e-2)" "unprognostic (4.87e-1)" "unprognostic (1.32e-2)" "unprognostic (3.30e-3)" "unprognostic (2.01e-2)" "unprognostic (3.02e-2)" "unprognostic (2.10e-1)" "unprognostic (1.98e-2)" "unprognostic (3.34e-1)" "unprognostic (2.96e-1)" "unprognostic (2.85e-2)" "unprognostic (2.70e-1)" "unprognostic (1.39e-3)" "unprognostic (1.86e-3)" "unprognostic (1.67e-1)" "unprognostic (1.75e-1)" "unprognostic (7.25e-2)" LSS OSC ENSG00000160285 "Lanosterol synthase" P48449 21 46188141-46228824 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Isomerase "Cataract, Disease variant, Hypotrichosis, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 127.6;Oligodendrocytes: 147.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032060, HPA032062, CAB034116" Supported NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 49: Hindbrain - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 62: Hepatocytes - Metabolism" 7 "CAB034116: AB_2138611, HPA032060: AB_10671085, HPA032062: AB_2674134" "unprognostic (2.78e-3)" "unprognostic (8.53e-3)" "unprognostic (6.95e-2)" "unprognostic (2.07e-1)" "unprognostic (1.74e-2)" "unprognostic (1.06e-1)" "unprognostic (2.74e-2)" "unprognostic (1.33e-2)" "unprognostic (1.72e-1)" "unprognostic (1.58e-2)" "unprognostic (1.68e-2)" "unprognostic (2.02e-2)" "unprognostic (2.34e-2)" "prognostic unfavorable (6.80e-4)" "unprognostic (1.92e-1)" "unprognostic (2.50e-1)" "prognostic unfavorable (3.07e-4)" LY75 "CD205, CLEC13B, DEC-205" ENSG00000054219 "Lymphocyte antigen 75" O60449 2 159803355-159904756 "CD markers, Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 76.3" "Cell type enhanced" "Detected in many" "Ciliated cells: 20.7;Distal enterocytes: 19.7;Proximal enterocytes: 31.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 19.6;Myeloma: 18.0" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB001450, HPA049108, HPA054073" Enhanced Approved "Golgi apparatus" NA NA 1300000 "Cluster 24: Non-specific - Transcription" "Cluster 71: Thymus - Adaptive immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 14: Langerhans cells - Innate immune response" "Golgi apparatus" "CAB001450: AB_563525, HPA049108: AB_2680635, HPA054073: AB_2682370" "unprognostic (7.29e-3)" "unprognostic (1.92e-3)" "unprognostic (3.15e-1)" "unprognostic (1.52e-2)" "unprognostic (4.60e-3)" "unprognostic (3.65e-2)" "unprognostic (8.87e-2)" "unprognostic (6.24e-2)" "unprognostic (2.80e-1)" "unprognostic (2.36e-1)" "unprognostic (8.74e-3)" "unprognostic (3.92e-1)" "prognostic unfavorable (2.39e-5)" "unprognostic (2.66e-1)" "unprognostic (4.89e-2)" "unprognostic (1.94e-2)" "prognostic favorable (3.86e-4)" MAGED2 "11B6, BCG1, HCA10, JCL-1, MAGE-D2, MAGED, MGC8386" ENSG00000102316 "MAGE family member D2" Q9UNF1 X 54807599-54816015 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Tumor antigen" "Bartter syndrome, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 536.3;Ovarian stromal cells: 371.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "testis cancer: 403.0" "Adipose visceral - Adipose progenitor cells, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA031572, HPA031573" Approved Enhanced Nucleoplasm,Nucleoli,Cytosol No No 120000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 62: Connective tissue - ECM organization" "Cluster 49: Hindbrain - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 50: Connective tissue cells - ECM organization" 1 "Nucleoplasm, Nucleoli, Cytosol" "HPA031572: AB_10599819, HPA031573: AB_10602181" "unprognostic (1.33e-1)" "unprognostic (8.60e-2)" "unprognostic (3.32e-1)" "unprognostic (1.69e-3)" "unprognostic (4.79e-2)" "unprognostic (3.52e-1)" "unprognostic (2.41e-3)" "unprognostic (1.39e-1)" "unprognostic (2.97e-1)" "prognostic favorable (2.88e-4)" "prognostic favorable (2.82e-4)" "unprognostic (6.34e-2)" "unprognostic (3.55e-3)" "prognostic unfavorable (9.43e-4)" "unprognostic (1.58e-1)" "unprognostic (9.77e-2)" "unprognostic (3.58e-1)" MANBA ENSG00000109323 "Mannosidase beta" O00462 4 102630770-102760994 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Microglial cells: 106.5;monocytes: 100.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 16.6" "Group enriched" "Detected in many" 5 "dendritic cells: 5.3;granulocytes: 16.6;monocytes: 9.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053478 Approved Supported Vesicles NA NA 15000000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 66: Non-specific - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 73: B-cells - B-cell function" Vesicles "HPA053478: AB_2682165" "unprognostic (2.29e-2)" "unprognostic (1.40e-1)" "unprognostic (3.80e-1)" "unprognostic (1.70e-1)" "prognostic unfavorable (7.56e-5)" "unprognostic (4.11e-2)" "prognostic unfavorable (3.74e-6)" "unprognostic (1.32e-1)" "unprognostic (2.19e-1)" "unprognostic (4.87e-2)" "unprognostic (7.78e-2)" "unprognostic (1.44e-2)" "unprognostic (1.33e-1)" "unprognostic (1.75e-2)" "unprognostic (7.12e-2)" "unprognostic (4.81e-2)" "unprognostic (2.13e-1)" MCM2 "BM28, CCNL1, cdc19, CDCL1, D3S3194, DFNA70, KIAA0030" ENSG00000073111 "Minichromosome maintenance complex component 2" P49736 3 127598410-127622436 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 66.8;lymphoid tissue: 36.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 62.9;Erythroid cells: 71.0;Extravillous trophoblasts: 24.4;Plasma cells: 24.8;Spermatogonia: 24.7;Syncytiotrophoblasts: 29.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB000303, HPA031450, HPA031495, HPA031496" Enhanced Enhanced Nucleoplasm Yes Yes 120000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 49: Hindbrain - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 52: Non-specific - Cell proliferation" 47 Nucleoplasm "CAB000303: AB_322519, HPA031450: , HPA031495: AB_2673904, HPA031496: AB_2673905" "unprognostic (2.43e-1)" "prognostic favorable (4.66e-4)" "unprognostic (4.44e-2)" "unprognostic (3.12e-3)" "unprognostic (1.68e-1)" "unprognostic (2.25e-2)" "prognostic unfavorable (1.51e-7)" "unprognostic (8.43e-3)" "unprognostic (1.92e-2)" "unprognostic (1.79e-1)" "unprognostic (1.41e-3)" "unprognostic (1.21e-2)" "unprognostic (1.16e-2)" "unprognostic (8.16e-3)" "unprognostic (1.56e-1)" "unprognostic (3.29e-2)" "unprognostic (2.82e-1)" MEI4 ENSG00000269964 "Meiotic double-stranded break formation protein 4" A8MW99 6 77650274-77927045 "Predicted intracellular proteins" "DNA recombination, Meiosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 4.0;testis: 3.3;thyroid gland: 2.1" "Cell type enriched" "Detected in some" 5 "Early spermatids: 111.3" "Cancer enhanced" "Detected in some" "renal cancer: 0.9;testis cancer: 1.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Outer root sheath cells, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 78: Testis - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 18: Early spermatids - Unknown function" 32 "unprognostic (3.47e-1)" "unprognostic (9.76e-2)" "unprognostic (2.51e-1)" "unprognostic (1.31e-1)" "unprognostic (1.11e-2)" "unprognostic (1.94e-1)" "unprognostic (1.88e-1)" "unprognostic (4.62e-2)" "unprognostic (9.70e-4)" "unprognostic (3.16e-1)" "unprognostic (2.86e-4)" "unprognostic (3.35e-2)" "unprognostic (4.17e-2)" "unprognostic (4.85e-2)" MFNG ENSG00000100060 "MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase" O00587 22 37469063-37486393 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Developmental protein, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 67.3" "Cell type enhanced" "Detected in many" "Adipocytes: 49.5;B-cells: 33.0;Endothelial cells: 40.4;Erythroid cells: 40.1;Hofbauer cells: 38.6;Kupffer cells: 39.9;monocytes: 40.5;NK-cells: 57.2;Plasma cells: 34.7;T-cells: 46.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Leukemia: 149.5;lymphoma: 165.2;Myeloma: 119.2" "Heart muscle - Endothelial cells, Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048936, HPA056479" Approved Approved Vesicles "Intracellular and membrane" "Developmental protein" NA NA 74000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 19: NK-cells - Adaptive immune response" Vesicles "HPA048936: AB_2680564, HPA056479: " "unprognostic (1.21e-1)" "unprognostic (4.17e-3)" "prognostic unfavorable (5.12e-4)" "prognostic favorable (1.65e-4)" "unprognostic (6.41e-3)" "unprognostic (1.00e-2)" "unprognostic (2.64e-1)" "unprognostic (2.36e-2)" "unprognostic (4.64e-2)" "unprognostic (2.91e-2)" "unprognostic (5.44e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (3.31e-5)" "unprognostic (2.67e-1)" "unprognostic (4.03e-2)" "unprognostic (3.86e-2)" "unprognostic (1.43e-1)" MGMT ENSG00000170430 "O-6-methylguanine-DNA methyltransferase" P16455 10 129467190-129770983 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Methyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 87.1" "Cell type enhanced" "Detected in all" "Hepatocytes: 560.9;Proximal tubular cells: 330.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB002786, HPA032135, HPA032136, HPA069497, CAB069881" Supported Enhanced Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 83: Liver - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 43: Hepatocytes - Metabolism" Nucleoplasm "CAB002786: , CAB069881: AB_10002128, HPA032135: AB_2674171, HPA032136: AB_2674172, HPA069497: AB_2732134" "unprognostic (1.10e-1)" "prognostic favorable (9.42e-4)" "unprognostic (1.48e-1)" "unprognostic (5.81e-2)" "unprognostic (7.84e-3)" "unprognostic (1.67e-1)" "prognostic favorable (1.54e-4)" "unprognostic (6.54e-3)" "unprognostic (4.71e-2)" "unprognostic (2.03e-1)" "unprognostic (1.26e-1)" "unprognostic (6.32e-1)" "unprognostic (4.89e-1)" "unprognostic (2.75e-1)" "unprognostic (1.95e-1)" "unprognostic (1.66e-1)" "unprognostic (1.08e-1)" MME "CALLA, CD10, NEP" ENSG00000196549 "Membrane metalloendopeptidase" P08473 3 155024124-155183704 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Charcot-Marie-Tooth disease, Disease variant, FDA approved drug targets, Neurodegeneration, Neuropathy, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 324.3;kidney: 292.0" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 76.6;Cytotrophoblasts: 78.8;Endometrial stromal cells: 269.5;Prostatic glandular cells: 119.5;Proximal enterocytes: 322.6;Syncytiotrophoblasts: 127.2" "Cancer enhanced" "Detected in many" "prostate cancer: 17.6" "Region enhanced" "Detected in all" "basal ganglia: 37.9" "Immune cell enriched" "Detected in some" 123 "neutrophil: 139.9" "Lineage enriched" "Detected in many" 123 "granulocytes: 139.9" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Fibroblasts, Kidney - Podocytes, Liver - Hepatocytes, Prostate - Prostate glandular cells" "Region enhanced" "Detected in many" "basal ganglia: 28.1" "Region enhanced" "Detected in all" "basal ganglia: 43.8" "CAB000013, HPA052583, HPA056072" Enhanced NA NA 320000 "Cluster 35: Neutrophils - Protein binding" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 74: Neutrophils - Degranulation" 3 "CAB000013: AB_563478, HPA052583: AB_2681872, HPA056072: AB_2683027" "unprognostic (1.36e-1)" "unprognostic (1.02e-3)" "unprognostic (8.52e-2)" "unprognostic (2.95e-1)" "unprognostic (2.78e-2)" "unprognostic (6.52e-3)" "unprognostic (1.20e-1)" "unprognostic (1.67e-2)" "unprognostic (8.67e-2)" "unprognostic (1.96e-1)" "unprognostic (7.30e-3)" "unprognostic (1.31e-1)" "unprognostic (2.71e-3)" "unprognostic (1.50e-1)" "unprognostic (7.29e-2)" "unprognostic (1.06e-2)" "unprognostic (1.37e-2)" MMP15 "MT2-MMP, MTMMP2, SMCP-2" ENSG00000102996 "Matrix metallopeptidase 15" P51511 16 58025754-58046901 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cholangiocytes: 51.5;Distal enterocytes: 88.5;Extravillous trophoblasts: 53.6;Proximal enterocytes: 59.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002611, HPA040390" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 5: Enterocytes - Absorption" "Plasma membrane, Cytosol" Nucleoplasm "CAB002611: , HPA040390: AB_2676956" "unprognostic (1.76e-2)" "unprognostic (7.32e-2)" "unprognostic (2.69e-1)" "unprognostic (6.85e-2)" "unprognostic (3.09e-1)" "unprognostic (1.68e-1)" "unprognostic (6.88e-3)" "unprognostic (1.40e-1)" "unprognostic (3.02e-2)" "unprognostic (1.24e-2)" "unprognostic (4.81e-2)" "unprognostic (1.81e-1)" "prognostic favorable (8.54e-8)" "unprognostic (3.63e-2)" "unprognostic (1.36e-1)" "unprognostic (1.28e-1)" "prognostic favorable (3.08e-4)" MOCOS "FLJ20733, HMCS, MOS" ENSG00000075643 "Molybdenum cofactor sulfurase" Q96EN8 18 36187497-36272157 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 9.9;liver: 15.6" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 19.4;Hepatocytes: 33.7;Proximal enterocytes: 22.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039412, HPA047958" Uncertain Supported Mitochondria,Cytosol NA NA "Cluster 83: Liver - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" 2 Mitochondria Cytosol "HPA039412: AB_2676496, HPA047958: AB_2680225" "unprognostic (3.07e-3)" "unprognostic (1.81e-1)" "unprognostic (1.69e-2)" "unprognostic (1.50e-1)" "unprognostic (3.18e-3)" "unprognostic (2.55e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (3.55e-4)" "unprognostic (5.84e-2)" "unprognostic (1.33e-1)" "prognostic unfavorable (1.29e-4)" "unprognostic (2.91e-2)" "prognostic unfavorable (3.03e-12)" "unprognostic (8.98e-2)" "unprognostic (2.37e-1)" "unprognostic (4.09e-1)" "unprognostic (6.35e-2)" MRGPRE "GPR167, mrgE" ENSG00000184350 "MAS related GPR family member E" Q86SM8 11 3225030-3232417 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.1;Erythroid cells: 1.1;Horizontal cells: 2.5" "Cancer enriched" "Detected in single" 5 "thyroid cancer: 0.9" "Region enhanced" "Detected in many" "pons: 58.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA046556 Uncertain NA NA "Cluster 49: Hindbrain - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "HPA046556: AB_10961404" "unprognostic (1.18e-1)" "unprognostic (7.52e-4)" "unprognostic (1.04e-1)" "unprognostic (9.09e-2)" "unprognostic (6.65e-2)" "unprognostic (1.77e-2)" "unprognostic (1.27e-1)" "unprognostic (1.83e-1)" "unprognostic (2.22e-2)" "unprognostic (1.19e-1)" MSMO1 "DESP4, ERG25, SC4MOL" ENSG00000052802 "Methylsterol monooxygenase 1" Q15800 4 165327667-165343164 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 558.3" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 436.0;Hepatocytes: 466.8;Suprabasal keratinocytes: 235.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055073, HPA056127" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 83: Liver - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 62: Hepatocytes - Metabolism" 14 "Endoplasmic reticulum" "HPA055073: , HPA056127: AB_2683045" "unprognostic (5.76e-2)" "prognostic unfavorable (2.97e-4)" "unprognostic (3.35e-2)" "unprognostic (7.85e-2)" "unprognostic (1.74e-1)" "unprognostic (1.20e-2)" "unprognostic (7.14e-2)" "unprognostic (1.75e-2)" "unprognostic (3.52e-2)" "unprognostic (2.06e-1)" "unprognostic (3.22e-3)" "unprognostic (2.28e-1)" "prognostic favorable (9.21e-4)" "unprognostic (2.39e-1)" "unprognostic (1.56e-2)" "unprognostic (3.54e-1)" "unprognostic (1.40e-1)" MTMR4 "KIAA0647, ZFYVE11" ENSG00000108389 "Myotubularin related protein 4" Q9NYA4 17 58489529-58517905 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 16: Non-specific - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 55: Non-specific - Transcription" 2 "unprognostic (3.07e-1)" "unprognostic (6.52e-2)" "unprognostic (4.87e-3)" "unprognostic (1.68e-2)" "unprognostic (1.54e-1)" "unprognostic (6.42e-2)" "unprognostic (4.97e-2)" "unprognostic (3.45e-3)" "unprognostic (6.82e-2)" "unprognostic (2.21e-1)" "prognostic favorable (5.09e-4)" "unprognostic (1.04e-1)" "prognostic unfavorable (1.53e-5)" "unprognostic (1.45e-1)" "unprognostic (2.13e-1)" "unprognostic (1.59e-2)" "unprognostic (2.92e-2)" MVD MPD ENSG00000167508 "Mevalonate diphosphate decarboxylase" P53602 16 88651935-88663161 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Lyase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 147.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041404, HPA048250" Uncertain Approved "Cell Junctions,Cytosol" NA NA 170000 "Cluster 13: Non-specific - Mitochondria" "Cluster 80: Non-specific - Endocytosis" "Cluster 49: Hindbrain - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 62: Hepatocytes - Metabolism" Cytosol "Cell Junctions" "HPA041404: AB_2677457, HPA048250: AB_2680329" "unprognostic (1.67e-1)" "unprognostic (3.05e-1)" "unprognostic (2.42e-1)" "prognostic favorable (2.17e-4)" "unprognostic (1.89e-1)" "unprognostic (9.56e-2)" "unprognostic (9.26e-3)" "unprognostic (8.33e-2)" "unprognostic (6.68e-2)" "unprognostic (5.47e-2)" "unprognostic (2.51e-1)" "unprognostic (6.22e-2)" "unprognostic (1.19e-3)" "unprognostic (4.12e-2)" "unprognostic (1.69e-1)" "unprognostic (2.11e-1)" "unprognostic (5.00e-2)" MVK "LRBP, MK" ENSG00000110921 "Mevalonate kinase" Q03426 12 109573255-109598125 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Kinase, Transferase" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 56.7" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 56.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016961, HPA044110" Approved Supported Vesicles,Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 62: Hepatocytes - Metabolism" 3 "Vesicles, Cytosol" "HPA016961: AB_1854220, HPA044110: " "unprognostic (3.10e-1)" "unprognostic (2.27e-2)" "unprognostic (1.85e-1)" "unprognostic (4.43e-2)" "unprognostic (3.66e-2)" "unprognostic (2.08e-2)" "unprognostic (4.30e-2)" "unprognostic (8.98e-2)" "unprognostic (1.05e-1)" "unprognostic (2.73e-2)" "unprognostic (8.23e-2)" "unprognostic (1.30e-1)" "unprognostic (6.43e-2)" "unprognostic (2.09e-1)" "unprognostic (1.58e-1)" "unprognostic (3.88e-1)" "unprognostic (3.28e-1)" MYBL1 "A-myb, AMYB" ENSG00000185697 "MYB proto-oncogene like 1" P10243 8 66562175-66614247 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 19.7;testis: 11.4" "Group enriched" "Detected in many" 4 "NK-cells: 182.7;T-cells: 84.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 1.9;MAIT T-cell: 1.3" "Lineage enhanced" "Detected in single" "T-cells: 1.9" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 123.9" "Adipose visceral - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Testis - Early spermatids, Testis - Spermatocytes, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA008791 Uncertain Supported Nucleoplasm NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 49: Hindbrain - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" Nucleoplasm "HPA008791: AB_1078540" "unprognostic (1.11e-1)" "unprognostic (2.47e-2)" "unprognostic (2.57e-1)" "unprognostic (7.23e-4)" "unprognostic (2.26e-1)" "unprognostic (1.89e-2)" "unprognostic (6.67e-3)" "unprognostic (2.38e-1)" "unprognostic (1.25e-1)" "unprognostic (3.78e-2)" "unprognostic (1.13e-2)" "unprognostic (3.74e-3)" "prognostic unfavorable (2.03e-8)" "unprognostic (2.04e-1)" "unprognostic (1.55e-1)" "unprognostic (1.75e-1)" "unprognostic (5.87e-2)" MYBPC2 "fsMyBP-C, MGC163408, MYBPCF" ENSG00000086967 "Myosin binding protein C2" Q14324 19 50432892-50466321 "Predicted intracellular proteins" "Cell adhesion" "Actin-binding, Muscle protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "skeletal muscle: 4185.0;tongue: 1152.9" "Cell type enriched" "Detected in some" 6 "Skeletal myocytes: 641.1" "Cancer enriched" "Detected in some" 9 "head and neck cancer: 9.9" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "lymphoma: 28.4;Myeloma: 45.1" "Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA042991 Enhanced NA NA 420000 "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 49: Hindbrain - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 2: Skeletal myocytes - Muscle contraction" "HPA042991: AB_2678257" "unprognostic (6.48e-3)" "unprognostic (2.65e-3)" "unprognostic (6.25e-2)" "unprognostic (3.26e-3)" "unprognostic (1.91e-3)" "unprognostic (2.15e-2)" "unprognostic (6.22e-3)" "unprognostic (2.46e-1)" "unprognostic (5.38e-2)" "unprognostic (9.65e-2)" "unprognostic (1.05e-1)" "unprognostic (1.30e-1)" "unprognostic (2.19e-8)" "unprognostic (1.85e-1)" "unprognostic (5.74e-2)" "unprognostic (2.73e-3)" "unprognostic (2.73e-1)" MYC "bHLHe39, c-Myc, MYCC" ENSG00000136997 "MYC proto-oncogene, bHLH transcription factor" P01106 8 127735434-127742951 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 246.4;skin 1: 280.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 601.9;Basal squamous epithelial cells: 992.6;Squamous epithelial cells: 677.0;Suprabasal keratinocytes: 633.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000084, CAB010307, HPA055893, HPA066556" Approved Enhanced Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 13: Skin - Cornification" "Cluster 49: Hindbrain - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 39: Non-specific - Basic cellular processes" 88 Nucleoplasm "CAB000084: , CAB010307: AB_631274, HPA055893: AB_2682960, HPA066556: AB_2685691" "unprognostic (1.45e-2)" "unprognostic (4.00e-3)" "unprognostic (3.94e-3)" "unprognostic (2.41e-3)" "unprognostic (8.14e-2)" "unprognostic (3.36e-3)" "unprognostic (5.80e-2)" "unprognostic (4.94e-3)" "unprognostic (1.59e-1)" "prognostic unfavorable (7.52e-4)" "unprognostic (5.19e-3)" "unprognostic (9.86e-3)" "prognostic unfavorable (5.49e-8)" "unprognostic (7.85e-2)" "unprognostic (4.66e-2)" "unprognostic (2.48e-1)" "prognostic unfavorable (4.96e-5)" MYZAP "GCOM1, Gup, Gup1, MYOZAP" ENSG00000263155 "Myocardial zonula adherens protein" P0CAP1 15 57591904-57685364 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "heart muscle: 567.9" "Cell type enriched" "Detected in many" 16 "Cardiomyocytes: 536.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "naive B-cell: 3.4;naive CD4 T-cell: 2.0" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Bile duct cancer: 15.3" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA039827 Approved NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 30: Heart muscle - Heart development" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 68: Cardiomyocytes - Muscle contraction" 1 "HPA039827: AB_10673364" "unprognostic (1.30e-2)" "unprognostic (1.25e-1)" "unprognostic (2.44e-1)" "unprognostic (1.66e-1)" "unprognostic (9.26e-3)" "unprognostic (1.49e-1)" "unprognostic (6.10e-3)" "unprognostic (5.19e-2)" "unprognostic (8.92e-2)" "unprognostic (2.30e-2)" "unprognostic (1.26e-1)" "unprognostic (9.67e-2)" "unprognostic (1.44e-1)" "unprognostic (1.12e-1)" "unprognostic (1.07e-1)" "unprognostic (3.86e-2)" "unprognostic (1.77e-2)" NAPG ENSG00000134265 "NSF attachment protein gamma" Q99747 18 10525905-10552764 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008208, HPA011389" Enhanced Supported "Plasma membrane" NA NA 8800 "Cluster 45: Eosinophils - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 49: Hindbrain - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 45: Non-specific - Mixed function" "Plasma membrane" "HPA008208: AB_1854305, HPA011389: AB_1854306" "unprognostic (1.23e-1)" "unprognostic (7.64e-3)" "unprognostic (6.96e-2)" "unprognostic (1.53e-1)" "unprognostic (9.83e-2)" "unprognostic (2.28e-1)" "unprognostic (1.28e-1)" "unprognostic (4.59e-2)" "unprognostic (1.55e-2)" "unprognostic (2.77e-3)" "unprognostic (1.46e-3)" "unprognostic (5.85e-2)" "prognostic favorable (8.14e-4)" "unprognostic (3.81e-2)" "unprognostic (2.87e-1)" "unprognostic (4.97e-2)" "unprognostic (6.96e-2)" NBPF4 FLJ32833 ENSG00000196427 "NBPF member 4" Q96M43 1 108222464-108244081 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "intestine: 1.1;testis: 4.3" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "breast cancer: 0.9" "Region enhanced" "Detected in some" "basal ganglia: 2.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 3.2" "Breast - Breast glandular cells, Testis - Early spermatids" "HPA045044, HPA046411, HPA047447, HPA058050" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 46: Testis - Spermatogenesis" "Cluster 49: Hindbrain - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 13: Spermatids - Transcription" "Nucleoplasm, Cytosol" "HPA045044: AB_2679196, HPA046411: AB_2679657, HPA047447: AB_2680051, HPA058050: " "unprognostic (6.33e-2)" "unprognostic (2.08e-1)" "unprognostic (2.18e-2)" "unprognostic (8.29e-2)" "unprognostic (2.90e-1)" "unprognostic (8.73e-2)" NDST4 ENSG00000138653 "N-deacetylase and N-sulfotransferase 4" Q9H3R1 4 114827763-115113876 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Distal tubular cells: 6.1;Inhibitory neurons: 28.1;Microglial cells: 4.5;Oligodendrocyte precursor cells: 14.6" "Not detected" "Not detected" "Region enhanced" "Detected in many" "pons: 19.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 6.4;lymphoma: 2.5;Sarcoma: 2.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA011129 Uncertain NA NA "Cluster 49: Hindbrain - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 69: Neurons - Neuronal signaling" "HPA011129: AB_1079460" "unprognostic (5.58e-2)" "unprognostic (5.90e-2)" "unprognostic (4.82e-1)" "unprognostic (1.71e-2)" "unprognostic (1.08e-1)" "unprognostic (1.11e-1)" "unprognostic (1.94e-1)" "unprognostic (6.55e-2)" NRG1 "GGF, HGL, HRG, NDF, NRG1-IT2" ENSG00000157168 "Neuregulin 1" Q02297 8 31639222-32855666 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 16.5" "Group enriched" "Detected in many" 13 "Excitatory neurons: 1418.8;Inhibitory neurons: 389.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "classical monocyte: 53.9" "Lineage enriched" "Detected in many" 5 "monocytes: 53.9" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010964 Uncertain Approved Nucleoplasm "Secreted to blood" "Growth factor" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 69: Liver - Oxidoreductase activity" "Cluster 49: Hindbrain - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 34: Neurons - Neuronal signaling" 1 Nucleoplasm "HPA010964: AB_1854641" "unprognostic (5.76e-3)" "unprognostic (8.60e-2)" "unprognostic (1.96e-4)" "unprognostic (2.67e-1)" "unprognostic (1.94e-4)" "unprognostic (4.99e-2)" "unprognostic (6.69e-2)" "unprognostic (7.72e-2)" "unprognostic (2.98e-1)" "unprognostic (5.65e-2)" "unprognostic (7.99e-2)" "unprognostic (8.49e-2)" "unprognostic (4.47e-2)" "unprognostic (1.31e-1)" "unprognostic (2.88e-1)" "unprognostic (5.40e-2)" "unprognostic (7.83e-2)" NRTN NTN ENSG00000171119 Neurturin Q99748 19 5805067-5828324 "Disease related genes, Predicted secreted proteins" "Growth factor" "Disease variant, Hirschsprung disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 24.8;pancreas: 16.4" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 22.1;Hepatocytes: 12.5;Rod photoreceptor cells: 44.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA065260 Approved "Golgi apparatus" "Secreted to blood" "Growth factor" NA NA "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 49: Hindbrain - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 66: Photoreceptor cells - Visual perception" "Golgi apparatus" "HPA065260: AB_2685448" "unprognostic (4.85e-2)" "unprognostic (1.66e-2)" "unprognostic (2.96e-2)" "prognostic favorable (3.86e-4)" "unprognostic (1.60e-2)" "prognostic favorable (7.23e-4)" "unprognostic (8.21e-3)" "unprognostic (5.60e-3)" "prognostic favorable (9.92e-4)" "unprognostic (1.38e-1)" "unprognostic (2.08e-2)" "unprognostic (1.28e-2)" "unprognostic (6.78e-3)" "unprognostic (3.39e-1)" "unprognostic (1.65e-1)" "unprognostic (1.22e-1)" "unprognostic (4.32e-2)" NTAQ1 "C8orf32, FLJ10204, WDYHV1" ENSG00000156795 "N-terminal glutamine amidase 1" Q96HA8 8 123416726-123470028 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024823, HPA053680" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 23: Non-specific - Cellular respiration" "Cluster 49: Hindbrain - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 6: Ovarian stromal cells - Transcription" 302 Nucleoplasm Vesicles "HPA024823: AB_1845773, HPA053680: AB_2682228" "unprognostic (9.97e-2)" "unprognostic (4.82e-2)" "unprognostic (3.48e-1)" "prognostic unfavorable (4.93e-5)" "unprognostic (1.69e-1)" "unprognostic (5.00e-2)" "prognostic unfavorable (3.47e-4)" "unprognostic (1.93e-2)" "unprognostic (1.20e-1)" "unprognostic (1.90e-1)" "unprognostic (1.19e-1)" "unprognostic (5.79e-2)" "unprognostic (2.81e-2)" "unprognostic (1.26e-1)" "unprognostic (5.39e-2)" "unprognostic (7.46e-2)" "unprognostic (2.37e-1)" NTPCR "C1orf57, HCR-NTPase, MGC13186, THEP1" ENSG00000135778 "Nucleoside-triphosphatase, cancer-related" Q9BSD7 1 232950605-232983882 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028125, HPA054304" Uncertain Approved Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 49: Hindbrain - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 39: Non-specific - Basic cellular processes" 2 Cytosol "HPA028125: AB_10601091, HPA054304: AB_2682443" "unprognostic (2.67e-1)" "unprognostic (2.28e-2)" "unprognostic (1.63e-2)" "unprognostic (7.59e-2)" "unprognostic (5.85e-3)" "unprognostic (1.04e-1)" "unprognostic (8.70e-3)" "unprognostic (2.12e-1)" "unprognostic (6.00e-2)" "unprognostic (5.03e-3)" "unprognostic (4.78e-2)" "unprognostic (1.08e-1)" "unprognostic (2.66e-1)" "unprognostic (2.74e-2)" "unprognostic (1.73e-1)" "unprognostic (1.08e-1)" "unprognostic (6.37e-3)" NTRK1 "MTC, TRK, TRKA" ENSG00000198400 "Neurotrophic receptor tyrosine kinase 1" P04629 1 156815636-156881850 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 6.8" "Group enriched" "Detected in some" 6 "Bipolar cells: 25.1;granulocytes: 39.3;Horizontal cells: 18.3" "Cancer enhanced" "Detected in some" "glioma: 1.3" "Group enriched" "Detected in all" 5 "cerebral cortex: 23.8;medulla oblongata: 30.7;pons: 47.8" "Immune cell enriched" "Detected in single" 116 "basophil: 94.9" "Lineage enriched" "Detected in single" 772 "granulocytes: 94.9" "Group enriched" "Detected in some" 8 "Leukemia: 9.0;Neuroblastoma: 17.4" "Heart muscle - Fibroblasts, Kidney - Intercalated cells, Lung - Mast cells, Stomach - Fibroblasts" "Region enhanced" "Detected in many" "basal ganglia: 8.4" "Region enriched" "Detected in single" 6 "basal ganglia: 5.4" "CAB004606, HPA035799, HPA076570, CAB080140" Enhanced Approved Vesicles,Cytosol NA NA 79000 "Cluster 46: Basophils - Proteolysis" "Cluster 74: Spermatids - Flagellum assembly" "Cluster 49: Hindbrain - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 30: Granulocytes - Unknown function" 6 "Vesicles, Cytosol" "CAB004606: AB_628397, CAB080140: , HPA035799: AB_2674788, HPA076570: " "unprognostic (5.89e-3)" "unprognostic (7.56e-2)" "unprognostic (2.74e-2)" "unprognostic (5.99e-3)" "unprognostic (7.26e-2)" "unprognostic (1.43e-3)" "unprognostic (1.56e-1)" "unprognostic (7.42e-3)" "unprognostic (7.63e-2)" "unprognostic (1.35e-1)" "unprognostic (6.73e-2)" "unprognostic (2.29e-2)" "unprognostic (3.18e-11)" "unprognostic (2.18e-3)" "unprognostic (3.79e-2)" "unprognostic (1.07e-1)" "unprognostic (4.89e-1)" NUB1 "BS4, NUB1L, NYREN18" ENSG00000013374 "Negative regulator of ubiquitin like proteins 1" Q9Y5A7 7 151341772-151378449 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 303.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021220, HPA050722, HPA053648" Approved Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 14: Langerhans cells - Innate immune response" 3 "Nucleoplasm, Nucleoli" "HPA021220: AB_2670630, HPA050722: AB_2681220, HPA053648: AB_2682217" "unprognostic (7.04e-3)" "unprognostic (2.47e-2)" "unprognostic (1.84e-1)" "unprognostic (1.01e-2)" "unprognostic (1.02e-2)" "unprognostic (3.22e-2)" "prognostic unfavorable (8.70e-4)" "unprognostic (1.42e-1)" "unprognostic (2.75e-1)" "unprognostic (2.67e-2)" "unprognostic (2.10e-1)" "unprognostic (8.76e-2)" "unprognostic (2.69e-2)" "unprognostic (9.44e-2)" "unprognostic (1.45e-1)" "unprognostic (2.64e-2)" "unprognostic (5.83e-3)" NXPH2 NPH2 ENSG00000144227 "Neurexophilin 2" O95156 2 138669157-138780390 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "brain: 2.8;kidney: 3.9;ovary: 4.2;retina: 2.2" "Cell type enriched" "Detected in some" 6 "Inhibitory neurons: 148.3" "Cancer enhanced" "Detected in single" "glioma: 0.5" "Group enriched" "Detected in many" 4 "medulla oblongata: 15.6;midbrain: 16.2;pons: 27.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 3.6;Rhabdoid: 6.5" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Kidney - Intercalated cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA034759 Approved "Secreted in brain" "No annotated function" NA Yes "Cluster 64: Neuronal - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 65: Neurons - Synaptic function" "HPA034759: AB_10669732" "unprognostic (5.83e-2)" "unprognostic (8.83e-2)" "unprognostic (1.41e-1)" "unprognostic (2.72e-1)" "unprognostic (1.80e-1)" OMP ENSG00000254550 "Olfactory marker protein" P47874 11 77102840-77103331 "Predicted intracellular proteins" "Olfaction, Sensory transduction" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 2.6;liver: 1.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in some" 62 "olfactory bulb: 96.7" NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "unprognostic (2.22e-1)" "unprognostic (2.44e-1)" "unprognostic (8.53e-2)" "unprognostic (3.54e-1)" "unprognostic (1.14e-2)" "unprognostic (1.50e-1)" "unprognostic (3.52e-3)" "unprognostic (2.10e-1)" "unprognostic (3.20e-2)" "unprognostic (4.23e-1)" "unprognostic (5.33e-3)" "unprognostic (3.94e-3)" "unprognostic (1.67e-1)" "unprognostic (1.04e-1)" "unprognostic (8.17e-2)" OPLAH "5-Opase, OPLA" ENSG00000178814 "5-oxoprolinase, ATP-hydrolysing" O14841 8 144051266-144063965 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 64.7" "Group enriched" "Detected in many" 4 "Early spermatids: 89.7;Late spermatids: 216.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.1;neutrophil: 1.1" "Group enriched" "Detected in many" 9 "granulocytes: 1.1;monocytes: 1.1" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026562, HPA028260, HPA052429" Uncertain Approved "Nucleoli fibrillar center" NA NA 34000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 44: Testis - Spermatogenesis" "Cluster 49: Hindbrain - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 63: Late spermatids - Spermatogenesis" 2 "Nucleoli fibrillar center" "HPA026562: AB_1854804, HPA028260: AB_10601383, HPA052429: AB_2681830" "unprognostic (7.89e-2)" "unprognostic (3.08e-2)" "unprognostic (1.69e-1)" "unprognostic (9.09e-2)" "unprognostic (2.21e-2)" "unprognostic (3.87e-3)" "unprognostic (2.04e-2)" "unprognostic (9.37e-2)" "unprognostic (2.90e-1)" "unprognostic (1.26e-1)" "unprognostic (6.82e-2)" "unprognostic (3.62e-1)" "prognostic favorable (1.53e-6)" "unprognostic (4.03e-3)" "unprognostic (4.33e-1)" "unprognostic (3.54e-2)" "unprognostic (8.24e-2)" OR13C2 ENSG00000276119 "Olfactory receptor family 13 subfamily C member 2" Q8NGS9 9 104604671-104605627 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA078297 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 49: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Plasma membrane" Nucleoplasm "HPA078297: " OR13C5 ENSG00000277556 "Olfactory receptor family 13 subfamily C member 5" Q8NGS8 9 104598457-104599413 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA078297 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 49: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Plasma membrane" Nucleoplasm "HPA078297: " "unprognostic (4.88e-2)" OSBPL5 "KIAA1534, OBPH1, ORP5" ENSG00000021762 "Oxysterol binding protein like 5" Q9H0X9 11 3087107-3166739 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 53.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 3.6;gdT-cell: 9.0;intermediate monocyte: 4.7;memory CD8 T-cell: 3.3;myeloid DC: 3.0;naive CD8 T-cell: 3.4;NK-cell: 11.0;non-classical monocyte: 11.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038335, HPA038712, HPA058727" Approved Enhanced Vesicles NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 49: Hindbrain - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 19: NK-cells - Adaptive immune response" Vesicles "HPA038335: AB_2675963, HPA038712: AB_10675949, HPA058727: AB_2683799" "unprognostic (6.02e-2)" "unprognostic (1.16e-1)" "unprognostic (1.68e-1)" "unprognostic (3.69e-2)" "unprognostic (8.22e-3)" "unprognostic (1.71e-1)" "unprognostic (1.25e-1)" "unprognostic (4.03e-3)" "unprognostic (1.29e-1)" "unprognostic (3.49e-3)" "unprognostic (2.16e-3)" "unprognostic (9.44e-2)" "unprognostic (2.78e-2)" "unprognostic (1.22e-1)" "unprognostic (6.50e-2)" "unprognostic (7.67e-2)" "unprognostic (2.60e-1)" PACSIN2 SDPII ENSG00000100266 "Protein kinase C and casein kinase substrate in neurons 2" Q9UNF0 22 42835412-43015149 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 96.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049854, HPA056520" Enhanced Supported "Nuclear speckles,Vesicles,Plasma membrane,Centriolar satellite" NA NA 2400000 "Cluster 7: Non-specific - Innate immune response" "Cluster 68: Non-specific - Protein processing" "Cluster 49: Hindbrain - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 5: Enterocytes - Absorption" 10 "Vesicles, Plasma membrane" "Nuclear speckles, Centriolar satellite" "HPA049854: AB_2680915, HPA056520: AB_2683163" "unprognostic (5.62e-3)" "unprognostic (1.22e-1)" "unprognostic (1.71e-2)" "unprognostic (1.64e-3)" "unprognostic (1.63e-2)" "unprognostic (3.96e-1)" "prognostic unfavorable (7.33e-4)" "unprognostic (4.48e-2)" "unprognostic (3.40e-2)" "unprognostic (2.82e-3)" "unprognostic (3.09e-2)" "unprognostic (1.00e-1)" "prognostic favorable (1.09e-13)" "unprognostic (2.87e-1)" "unprognostic (1.11e-1)" "unprognostic (6.20e-2)" "unprognostic (2.95e-1)" PALM3 ENSG00000187867 "Paralemmin 3" A6NDB9 19 14053363-14062076 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 45.6;liver: 54.4;stomach 1: 29.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 15.6;Basal prostatic cells: 28.5;Cholangiocytes: 19.1;Collecting duct cells: 37.0;Exocrine glandular cells: 18.9;Hepatocytes: 34.7;Oocytes: 22.1;Spermatogonia: 21.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 19.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA052794, HPA056119" Enhanced Approved "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA "Cluster 1: Liver & Kidney - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 3: Basal prostatic cells - Lipid metabolism" 1 "Nucleoplasm, Nuclear bodies" "Plasma membrane" "HPA052794: AB_2681952, HPA056119: AB_2683042" "unprognostic (3.67e-2)" "unprognostic (9.08e-2)" "unprognostic (4.72e-2)" "prognostic unfavorable (7.87e-4)" "unprognostic (2.14e-2)" "unprognostic (1.47e-1)" "unprognostic (4.66e-2)" "unprognostic (7.62e-2)" "unprognostic (1.97e-1)" "unprognostic (3.91e-1)" "unprognostic (3.93e-2)" "unprognostic (3.88e-2)" "unprognostic (2.09e-2)" "unprognostic (1.06e-1)" "unprognostic (5.68e-2)" "unprognostic (1.10e-2)" "unprognostic (1.72e-3)" PCBP3 "FLJ44028, PCBP3-OT1, PCBP3OT" ENSG00000183570 "Poly(rC) binding protein 3" P57721 21 45643694-45942454 "Plasma proteins, Predicted intracellular proteins" "DNA-binding, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 59.8;retina: 79.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 135.5;Cone photoreceptor cells: 61.2;Early spermatids: 35.6;Horizontal cells: 95.0;Late spermatids: 74.3;Muller glia cells: 38.7;Rod photoreceptor cells: 68.5;Spermatocytes: 33.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.0" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Neuroblastoma: 37.3" "Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in all" 5 "olfactory bulb: 229.2" "Region enhanced" "Detected in all" "olfactory bulb: 111.2" "HPA030247, HPA073145" Approved Uncertain Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 41: Basophils - Unknown function" "Cluster 28: Neuronal - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 25: Bipolar cells - Visual perception" "Nucleoplasm, Mitochondria" Vesicles "HPA030247: AB_10601244, HPA073145: " "unprognostic (3.88e-2)" "unprognostic (1.19e-1)" "unprognostic (2.01e-4)" "unprognostic (9.89e-4)" "unprognostic (2.74e-1)" "unprognostic (1.40e-1)" "unprognostic (4.10e-2)" "unprognostic (2.42e-1)" "unprognostic (3.87e-2)" "unprognostic (1.64e-3)" "unprognostic (1.12e-3)" "unprognostic (1.97e-2)" "unprognostic (1.96e-6)" "unprognostic (8.67e-2)" "unprognostic (2.32e-2)" "unprognostic (8.04e-2)" "unprognostic (1.97e-2)" PCYT2 ET ENSG00000185813 "Phosphate cytidylyltransferase 2, ethanolamine" Q99447 17 81900958-81911432 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 161.7;testis: 254.4" "Cell type enriched" "Detected in many" 4 "Late spermatids: 2753.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023033, HPA023034" Enhanced Approved Nucleoplasm,Cytosol NA NA 84000 "Cluster 14: Non-specific - Unknown function" "Cluster 42: Testis - Spermatogenesis" "Cluster 49: Hindbrain - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 36: Late spermatids - Unknown function" 4 Cytosol Nucleoplasm "HPA023033: AB_1855094, HPA023034: AB_1855095" "unprognostic (4.05e-3)" "unprognostic (4.39e-3)" "unprognostic (3.81e-1)" "unprognostic (9.72e-2)" "unprognostic (1.92e-1)" "unprognostic (9.86e-2)" "unprognostic (1.24e-2)" "unprognostic (1.06e-1)" "unprognostic (4.24e-1)" "unprognostic (8.97e-3)" "unprognostic (1.84e-1)" "unprognostic (2.34e-1)" "prognostic favorable (4.29e-6)" "unprognostic (1.19e-1)" "unprognostic (8.59e-2)" "unprognostic (1.63e-1)" "unprognostic (4.47e-2)" PDCD6IP "AIP1, Alix, Hp95" ENSG00000170248 "Programmed cell death 6 interacting protein" Q8WUM4 3 33798571-33869707 "Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Host-virus interaction, Protein transport, Transport" "Intellectual disability, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011905, CAB016212, HPA051110, HPA051604" Supported Approved Vesicles,Centrosome "Intracellular and membrane" Transport NA NA 4100000 "Cluster 40: Monocytes - Innate immune response" "Cluster 45: Intestine - Digestion" "Cluster 49: Hindbrain - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 5: Enterocytes - Absorption" 15 Vesicles Centrosome "CAB016212: AB_673819, HPA011905: AB_1855111, HPA051110: , HPA051604: " "unprognostic (1.53e-1)" "unprognostic (2.63e-1)" "prognostic favorable (1.16e-4)" "unprognostic (2.17e-1)" "unprognostic (2.75e-1)" "unprognostic (5.12e-2)" "unprognostic (7.76e-3)" "unprognostic (1.23e-2)" "unprognostic (3.29e-1)" "unprognostic (2.86e-1)" "unprognostic (3.88e-3)" "unprognostic (4.49e-2)" "prognostic favorable (3.90e-9)" "unprognostic (9.61e-2)" "unprognostic (1.89e-1)" "unprognostic (4.78e-1)" "unprognostic (1.11e-1)" PDLIM2 ENSG00000120913 "PDZ and LIM domain 2" Q96JY6 8 22578279-22598025 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 320.1;Syncytiotrophoblasts: 814.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Region enhanced" "Detected in all" "white matter: 429.4" "Low region specificity" "Detected in many" HPA003880 Approved Supported "Actin filaments,Focal adhesion sites" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 49: Hindbrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 1 "Actin filaments, Focal adhesion sites" "HPA003880: AB_1855149" "unprognostic (1.04e-1)" "unprognostic (3.53e-2)" "unprognostic (1.80e-2)" "unprognostic (1.03e-1)" "unprognostic (1.45e-3)" "unprognostic (9.33e-2)" "unprognostic (3.69e-2)" "unprognostic (4.55e-2)" "unprognostic (1.79e-2)" "unprognostic (1.22e-3)" "unprognostic (1.52e-1)" "unprognostic (3.37e-1)" "prognostic unfavorable (1.37e-7)" "unprognostic (6.14e-2)" "unprognostic (8.17e-2)" "unprognostic (3.47e-2)" "unprognostic (3.08e-3)" PDRG1 "C20orf126, dJ310O13.3" ENSG00000088356 "P53 and DNA damage regulated 1" Q9NUG6 20 31944337-31952046 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 77.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047084, HPA063542" Approved Approved "Actin filaments" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 49: Hindbrain - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 3: Basal prostatic cells - Lipid metabolism" 4 "Actin filaments" "HPA047084: AB_2679925, HPA063542: AB_2685035" "unprognostic (2.17e-1)" "unprognostic (9.77e-2)" "unprognostic (1.49e-1)" "prognostic unfavorable (1.69e-4)" "unprognostic (8.51e-2)" "unprognostic (1.06e-1)" "prognostic unfavorable (2.62e-5)" "unprognostic (1.01e-1)" "unprognostic (1.70e-1)" "unprognostic (1.59e-1)" "unprognostic (3.82e-3)" "unprognostic (2.44e-2)" "unprognostic (1.30e-1)" "unprognostic (1.22e-1)" "unprognostic (3.04e-2)" "unprognostic (1.66e-1)" "unprognostic (1.00e-2)" PLA2G3 GIII-SPLA2 ENSG00000100078 "Phospholipase A2 group III" Q9NZ20 22 31134807-31140508 "Enzymes, Metabolic proteins, Predicted secreted proteins, RAS pathway related proteins" "Cilium biogenesis/degradation, Lipid metabolism, Mast cell degranulation, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 13.4;skin 1: 14.9;vagina: 6.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 17.9;Basal keratinocytes: 4.1;Breast glandular cells: 7.5;Suprabasal keratinocytes: 20.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 3.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 11.5" "Lung - Alveolar cells type 2, Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA021016 Uncertain Uncertain "Endoplasmic reticulum,Golgi apparatus" "Secreted to blood" Enzyme NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 49: Hindbrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 17: Breast glandular cells - Lactation" "Golgi apparatus" "Endoplasmic reticulum" "HPA021016: AB_1855443" "unprognostic (1.80e-1)" "unprognostic (4.63e-3)" "unprognostic (1.07e-1)" "unprognostic (1.49e-2)" "unprognostic (9.72e-2)" "prognostic favorable (4.47e-4)" "unprognostic (1.74e-2)" "unprognostic (2.30e-1)" "unprognostic (4.25e-2)" "unprognostic (9.55e-3)" "unprognostic (4.41e-1)" "unprognostic (3.67e-1)" "unprognostic (3.29e-1)" "unprognostic (9.49e-3)" "unprognostic (3.72e-2)" PLA2G4A "cPLA2-alpha, PLA2G4" ENSG00000116711 "Phospholipase A2 group IVA" P47712 1 186828949-186988981 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Glycerol metabolism, Leukotriene biosynthesis, Lipid biosynthesis, Lipid degradation, Lipid metabolism, Phospholipid degradation, Phospholipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 84.3;seminal vesicle: 46.6" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 64.3;Microglial cells: 110.0;Secretory cells: 30.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 6.8;eosinophil: 7.9;intermediate monocyte: 8.4;myeloid DC: 7.7;non-classical monocyte: 4.0;plasmacytoid DC: 3.1" "Group enriched" "Detected in many" 7 "dendritic cells: 7.7;granulocytes: 7.9;monocytes: 8.4" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Skin - Mitotic cells (Skin), Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010050, HPA050062, HPA054206" Approved Supported Vesicles,Cytosol NA NA 35000 "Cluster 29: Non-specific - Unknown function" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 49: Hindbrain - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 3: Basal prostatic cells - Lipid metabolism" Cytosol Vesicles "CAB010050: AB_631312, HPA050062: AB_2681002, HPA054206: AB_2682417" "prognostic favorable (9.07e-4)" "unprognostic (1.18e-1)" "unprognostic (2.03e-1)" "prognostic favorable (2.85e-4)" "unprognostic (5.55e-2)" "unprognostic (1.51e-3)" "unprognostic (2.67e-2)" "unprognostic (2.43e-1)" "unprognostic (2.63e-1)" "unprognostic (7.14e-3)" "unprognostic (1.50e-1)" "unprognostic (1.68e-1)" "unprognostic (2.96e-2)" "unprognostic (8.07e-2)" "unprognostic (1.58e-1)" "unprognostic (1.90e-2)" "unprognostic (4.26e-2)" PLPP4 "DPPL2, PPAPDC1, PPAPDC1A" ENSG00000203805 "Phospholipid phosphatase 4" Q5VZY2 10 120457227-120592065 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 4 "brain: 3.8" "Cell type enriched" "Detected in some" 5 "Oligodendrocyte precursor cells: 142.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045188 Approved Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 49: Hindbrain - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 76: Oligodendrocyte precursor - Unknown function" 29 "Nucleoli, Nucleoli rim" Nucleoplasm "HPA045188: AB_2679246" "unprognostic (8.19e-2)" "unprognostic (2.94e-2)" "unprognostic (8.86e-2)" "unprognostic (1.90e-3)" "unprognostic (3.45e-1)" "unprognostic (2.92e-2)" "unprognostic (2.69e-1)" "unprognostic (2.26e-3)" "unprognostic (1.55e-1)" "unprognostic (8.62e-3)" "unprognostic (2.70e-3)" "unprognostic (1.89e-1)" "unprognostic (2.40e-3)" "unprognostic (3.49e-2)" "unprognostic (3.75e-2)" "unprognostic (1.11e-1)" "unprognostic (1.21e-3)" PNPLA2 "ATGL, desnutrin, FP17548, iPLA2zeta, TTS-2.2" ENSG00000177666 "Patatin like phospholipase domain containing 2" Q96AD5 11 818914-825573 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 491.9;breast: 349.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055173, HPA062602, HPA075175" Approved Enhanced "Nucleoplasm,Lipid droplets" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 49: Non-specific - Transcription" 1 "Lipid droplets" Nucleoplasm "HPA055173: AB_2682725, HPA062602: AB_2684804, HPA075175: " "unprognostic (2.11e-2)" "unprognostic (3.37e-2)" "unprognostic (5.87e-3)" "unprognostic (2.51e-2)" "unprognostic (8.97e-3)" "unprognostic (1.68e-2)" "unprognostic (6.39e-2)" "unprognostic (3.28e-2)" "unprognostic (3.00e-1)" "unprognostic (5.61e-2)" "unprognostic (7.93e-2)" "unprognostic (2.09e-2)" "unprognostic (1.10e-1)" "unprognostic (1.68e-1)" "unprognostic (5.46e-1)" "unprognostic (4.09e-1)" "unprognostic (2.07e-2)" POU4F2 "Brn-3b, BRN3B" ENSG00000151615 "POU class 4 homeobox 2" Q12837 4 146638893-146642474 "Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 1.0;testis: 1.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.6;Granulosa cells: 1.1;Horizontal cells: 4.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 22 "medulla oblongata: 6.5;midbrain: 16.7;pons: 10.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.3;Gastric cancer: 2.6" "Testis - Early spermatids" "Region enriched" "Detected in single" 6 "midbrain: 4.4" "Low region specificity" "Detected in many" NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 49: Hindbrain - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 62 "unprognostic (4.18e-2)" PRKG2 "cGKII, PKG2, PRKGR2" ENSG00000138669 "Protein kinase cGMP-dependent 2" Q13237 4 81087370-81215222 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 13.3;prostate: 9.6" "Cell type enhanced" "Detected in some" "Excitatory neurons: 31.6;Inhibitory neurons: 63.1;Oligodendrocyte precursor cells: 100.0;Prostatic glandular cells: 25.7;Proximal enterocytes: 18.4" "Group enriched" "Detected in some" 4 "melanoma: 4.1;prostate cancer: 2.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Alveolar cells type 1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA007386, CAB018739" Approved NA NA "Cluster 41: Basophils - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 49: Hindbrain - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 15: Non-specific - Mixed function" "CAB018739: AB_2284387, HPA007386: AB_1079678" "unprognostic (6.14e-2)" "unprognostic (2.77e-1)" "unprognostic (2.14e-1)" "unprognostic (5.01e-4)" "unprognostic (4.33e-2)" "unprognostic (6.85e-2)" "unprognostic (1.13e-1)" "unprognostic (5.57e-2)" "unprognostic (2.05e-1)" "unprognostic (1.86e-1)" "unprognostic (4.70e-2)" "unprognostic (1.48e-1)" "unprognostic (8.27e-2)" "unprognostic (2.33e-1)" "unprognostic (1.58e-1)" "unprognostic (4.00e-3)" "unprognostic (1.06e-1)" PRPSAP1 PAP39 ENSG00000161542 "Phosphoribosyl pyrophosphate synthetase associated protein 1" Q14558 17 76309478-76384521 "Predicted intracellular proteins" "Nucleotide biosynthesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 169.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062396 Approved Cytosol NA NA 24000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 68: Non-specific - Protein processing" "Cluster 49: Hindbrain - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 10: Muller glia cells - Visual perception" 5 Cytosol "HPA062396: AB_2684750" "unprognostic (1.12e-1)" "unprognostic (3.37e-2)" "prognostic favorable (1.39e-5)" "unprognostic (3.31e-2)" "unprognostic (3.11e-2)" "unprognostic (8.45e-3)" "unprognostic (1.09e-1)" "unprognostic (7.19e-2)" "unprognostic (2.66e-2)" "unprognostic (2.37e-2)" "unprognostic (6.51e-2)" "unprognostic (4.10e-3)" "unprognostic (1.29e-1)" "unprognostic (1.22e-1)" "unprognostic (5.72e-2)" "unprognostic (8.20e-2)" "unprognostic (5.37e-2)" PRSS56 ENSG00000237412 "Serine protease 56" P0CW18 2 232520388-232525716 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "retina: 5.1;skeletal muscle: 9.3" "Group enriched" "Detected in some" 10 "Early spermatids: 11.6;Late spermatids: 15.7;Muller glia cells: 41.9;Skeletal myocytes: 13.7" "Group enriched" "Detected in many" 4 "cervical cancer: 1.2;colorectal cancer: 2.5;endometrial cancer: 1.4;melanoma: 2.1;urothelial cancer: 4.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 7.1;head and neck cancer: 15.7" "Testis - Late spermatids" "Group enriched" "Detected in some" 10 "basal ganglia: 1.9;olfactory bulb: 4.2" "Region enhanced" "Detected in many" "olfactory bulb: 18.6" NA NA "Cluster 3: Non-specific - Unknown function" "Cluster 49: Hindbrain - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 10: Muller glia cells - Visual perception" "unprognostic (3.26e-1)" "unprognostic (1.98e-2)" "unprognostic (1.31e-1)" "unprognostic (3.73e-3)" "unprognostic (2.28e-1)" "unprognostic (7.15e-2)" "unprognostic (4.64e-2)" "unprognostic (1.20e-1)" PTGES "MGST-IV, MGST1-L1, MGST1L1, PIG12, TP53I12" ENSG00000148344 "Prostaglandin E synthase" O14684 9 129738331-129753042 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Isomerase, Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 81.3;urinary bladder: 75.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 90.7;Basal respiratory cells: 109.3;Cytotrophoblasts: 155.4;Extravillous trophoblasts: 333.3;Ionocytes: 92.4;Syncytiotrophoblasts: 300.1" "Cancer enhanced" "Detected in all" "urothelial cancer: 69.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "basophil: 29.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 29.0" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045064 Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 58: Placenta - Pregnancy" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 4: Extravillous trophoblasts - Unknown function" 15 "Endoplasmic reticulum" "HPA045064: AB_10795889" "unprognostic (2.92e-3)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.32e-4)" "unprognostic (2.54e-2)" "unprognostic (1.94e-3)" "unprognostic (1.25e-1)" "unprognostic (5.38e-3)" "unprognostic (1.24e-3)" "unprognostic (2.92e-1)" "unprognostic (1.61e-1)" "prognostic unfavorable (7.97e-5)" "unprognostic (2.22e-1)" "unprognostic (4.66e-2)" "unprognostic (9.78e-3)" "unprognostic (3.19e-2)" "unprognostic (1.30e-1)" "unprognostic (5.20e-2)" PTPN20 "bA142I17.1, bA42B19.1, CT126, DKFZP566K0524, PTPN20A, PTPN20B" ENSG00000204179 "Protein tyrosine phosphatase non-receptor type 20" Q4JDL3 10 46911396-47002488 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 13.2;tongue: 14.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 16.4;Distal tubular cells: 27.7;Early spermatids: 21.1;Late spermatids: 33.5;Proximal tubular cells: 13.8;Spermatocytes: 21.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in single" "midbrain: 1.6" "HPA043337, HPA046896, HPA048310, HPA069148" Enhanced Supported "Centriolar satellite" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 78: Testis - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 13: Spermatids - Transcription" "Centriolar satellite" "HPA043337: AB_2678436, HPA046896: , HPA048310: AB_2680350, HPA069148: " "unprognostic (1.08e-1)" "unprognostic (1.30e-1)" "unprognostic (3.04e-2)" "unprognostic (2.82e-3)" "unprognostic (6.78e-2)" "unprognostic (1.85e-1)" "unprognostic (8.44e-2)" "unprognostic (1.92e-1)" "unprognostic (1.53e-1)" "unprognostic (2.22e-2)" "unprognostic (2.83e-1)" "unprognostic (1.24e-1)" "unprognostic (1.06e-1)" "unprognostic (1.62e-1)" "unprognostic (1.48e-2)" "unprognostic (1.75e-1)" "unprognostic (8.34e-2)" RASGEF1B "FLJ31695, GPIG4" ENSG00000138670 "RasGEF domain family member 1B" Q0VAM2 4 81426393-82044244 "Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 40.5" "Cell type enhanced" "Detected in many" "granulocytes: 220.6;Langerhans cells: 321.3;Macrophages: 187.0;monocytes: 520.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "intermediate monocyte: 11.9;memory B-cell: 9.7;naive B-cell: 12.4;non-classical monocyte: 20.7;plasmacytoid DC: 27.9" "Group enriched" "Detected in all" 5 "B-cells: 12.4;dendritic cells: 27.9;monocytes: 20.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044574 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 49: Hindbrain - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 29: Monocytes - Innate immune response" Nucleoplasm Vesicles "HPA044574: AB_10794292" "unprognostic (3.24e-1)" "prognostic favorable (6.40e-4)" "unprognostic (1.32e-1)" "unprognostic (1.53e-1)" "unprognostic (1.19e-1)" "prognostic favorable (1.49e-5)" "unprognostic (4.42e-2)" "unprognostic (6.31e-2)" "unprognostic (4.43e-1)" "unprognostic (4.85e-2)" "unprognostic (1.13e-2)" "unprognostic (3.88e-2)" "prognostic favorable (4.21e-6)" "unprognostic (4.19e-3)" "unprognostic (1.44e-2)" "unprognostic (3.19e-2)" "unprognostic (6.04e-2)" RBP3 "D10S64, D10S65, D10S66, RP66" ENSG00000265203 "Retinol binding protein 3" P10745 10 47348363-47357881 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" Transport "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 179 "retina: 525.9" "Group enriched" "Detected in some" 11 "Bipolar cells: 444.0;Cone photoreceptor cells: 1364.4;Rod photoreceptor cells: 1741.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hippocampal formation: 1.3" "Low region specificity" "Detected in many" "HPA041301, HPA044239" Enhanced "Secreted in other tissues" Transport NA NA "Cluster 76: Retina - Visual perception" "Cluster 49: Hindbrain - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" 9 "HPA041301: AB_2677398, HPA044239: AB_2678868" "unprognostic (3.48e-2)" "unprognostic (4.78e-3)" "unprognostic (1.36e-2)" "unprognostic (4.02e-2)" "unprognostic (1.40e-1)" "unprognostic (1.58e-2)" "unprognostic (5.09e-2)" "unprognostic (5.14e-3)" "unprognostic (7.44e-2)" "unprognostic (1.23e-1)" "unprognostic (4.68e-3)" REC8 "kleisin-alpha, REC8L1, Rec8p" ENSG00000100918 "REC8 meiotic recombination protein" O95072 14 24171853-24180257 "Plasma proteins, Predicted intracellular proteins" "Chromosome partition, Meiosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 67.0" "Cell type enhanced" "Detected in many" "Early spermatids: 169.5;Gastric mucus-secreting cells: 76.6;Late spermatids: 79.1;Mesothelial cells: 117.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Neuroblastoma: 23.4;testis cancer: 23.9" "Adipose visceral - Mesothelial cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031727, HPA031729" Approved Approved Nucleoplasm NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 65: Cerebellum - Nervous system development" "Cluster 49: Hindbrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 42: Ciliated cells - Cilium assembly" 2 Nucleoplasm "HPA031727: AB_10602920, HPA031729: AB_10669915" "prognostic favorable (2.19e-4)" "unprognostic (2.57e-2)" "unprognostic (2.15e-2)" "unprognostic (1.77e-2)" "unprognostic (2.00e-1)" "unprognostic (5.10e-3)" "unprognostic (1.00e-1)" "unprognostic (1.21e-2)" "unprognostic (3.16e-1)" "unprognostic (1.31e-1)" "prognostic favorable (5.57e-4)" "unprognostic (1.16e-1)" "prognostic unfavorable (1.41e-7)" "unprognostic (8.98e-2)" "unprognostic (2.12e-1)" "unprognostic (1.88e-2)" "unprognostic (6.40e-3)" RFLNA "Cfm2, FAM101A, FLJ44614, RefilinA" ENSG00000178882 "Refilin A" Q6ZTI6 12 123973241-124316024 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "stomach 1: 92.2" "Cell type enhanced" "Detected in some" "Distal enterocytes: 27.5;Enteroendocrine cells: 14.7;Gastric mucus-secreting cells: 111.4;Intestinal goblet cells: 47.7;Paneth cells: 17.0;Undifferentiated cells: 14.4" "Cancer enhanced" "Detected in many" "stomach cancer: 19.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA078021 Enhanced Approved "Focal adhesion sites" NA NA "Cluster 45: Intestine - Digestion" "Cluster 49: Hindbrain - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Non-specific - Mixed function" "Focal adhesion sites" "HPA078021: AB_2732368" "unprognostic (1.71e-1)" "unprognostic (6.85e-2)" "unprognostic (1.63e-2)" "unprognostic (1.36e-1)" "unprognostic (3.15e-2)" "unprognostic (8.78e-4)" "unprognostic (2.01e-1)" "prognostic unfavorable (3.16e-5)" "unprognostic (8.87e-2)" "unprognostic (1.59e-1)" "unprognostic (1.71e-3)" "unprognostic (1.15e-3)" "unprognostic (1.77e-8)" "unprognostic (2.48e-1)" "unprognostic (1.36e-1)" "unprognostic (6.27e-2)" "unprognostic (1.37e-2)" RFX5 ENSG00000143390 "Regulatory factor X5" P48382 1 151340640-151347326 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018519, HPA079241" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 49: Hindbrain - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 14: Langerhans cells - Innate immune response" 3 Nucleoplasm Vesicles "HPA018519: AB_1856209, HPA079241: " "unprognostic (1.17e-3)" "unprognostic (1.62e-1)" "unprognostic (2.61e-1)" "unprognostic (3.21e-2)" "unprognostic (2.68e-2)" "unprognostic (2.49e-2)" "unprognostic (3.73e-2)" "unprognostic (2.09e-3)" "unprognostic (2.99e-2)" "unprognostic (1.96e-1)" "unprognostic (8.29e-2)" "unprognostic (4.42e-2)" "unprognostic (5.66e-3)" "unprognostic (2.00e-3)" "unprognostic (3.43e-2)" "unprognostic (4.03e-2)" "unprognostic (3.05e-2)" RGPD1 RGP1 ENSG00000187627 "RANBP2 like and GRIP domain containing 1" 2 86913783-87013976 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "cervix: 8.2;placenta: 9.5;testis: 23.5" "Cell type enhanced" "Detected in some" "Early spermatids: 2.7;Excitatory neurons: 4.1;Inhibitory neurons: 3.8;Late spermatids: 3.4;Microglial cells: 2.7;Oligodendrocyte precursor cells: 1.4;Oligodendrocytes: 1.7;Rod photoreceptor cells: 1.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 11 "testis cancer: 11.2" "HPA049497, HPA051675, HPA067564" Uncertain Approved "Nuclear membrane,Vesicles" NA NA "Cluster 21: Testis - Unknown function" "Cluster 49: Hindbrain - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 8: Neurons - Neuronal signaling" "Nuclear membrane, Vesicles" "HPA049497: AB_2680794, HPA051675: AB_2681570, HPA067564: AB_2685862" "unprognostic (8.24e-2)" "unprognostic (6.05e-2)" "unprognostic (6.41e-2)" "unprognostic (1.39e-2)" "unprognostic (9.06e-2)" "unprognostic (6.28e-2)" "unprognostic (1.80e-1)" "unprognostic (2.42e-2)" "unprognostic (1.48e-1)" "unprognostic (2.30e-1)" "unprognostic (1.88e-5)" "unprognostic (2.23e-1)" "unprognostic (2.22e-2)" "unprognostic (5.36e-3)" "unprognostic (1.99e-2)" RGPD3 RGP3 ENSG00000153165 "RANBP2 like and GRIP domain containing 3" A6NKT7 2 106391290-106468413 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 5 "lymphoid tissue: 1.9;testis: 6.7" "Cell type enhanced" "Detected in some" "Early spermatids: 20.2;Late spermatids: 6.4;Spermatocytes: 4.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Leukemia: 2.4" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "HPA049497, HPA051675, HPA067564" Uncertain Approved "Nuclear membrane,Vesicles" NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 49: Hindbrain - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 13: Spermatids - Transcription" "Nuclear membrane, Vesicles" "HPA049497: AB_2680794, HPA051675: AB_2681570, HPA067564: AB_2685862" "unprognostic (2.91e-1)" "unprognostic (1.62e-1)" "unprognostic (5.51e-2)" "unprognostic (6.61e-2)" "unprognostic (2.53e-1)" "unprognostic (1.33e-1)" "unprognostic (1.26e-1)" "unprognostic (6.86e-2)" "unprognostic (3.10e-1)" "unprognostic (2.49e-2)" "unprognostic (3.70e-1)" "unprognostic (3.44e-1)" "unprognostic (4.74e-3)" "unprognostic (5.05e-2)" "unprognostic (3.70e-1)" "unprognostic (3.42e-1)" "unprognostic (1.34e-1)" RNF223 ENSG00000237330 "Ring finger protein 223" E7ERA6 1 1070967-1074306 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "cervix: 10.3;esophagus: 25.4;vagina: 12.6" "Cell type enhanced" "Detected in many" "Breast glandular cells: 26.7;Distal enterocytes: 16.7;Extravillous trophoblasts: 22.6;Gastric mucus-secreting cells: 38.9;Glandular and luminal cells: 32.8;Mucus glandular cells: 17.5;Paneth cells: 19.4;Suprabasal keratinocytes: 27.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 37: Glandular & Luminal cells - Unknown function" "unprognostic (4.71e-1)" "unprognostic (2.79e-1)" "unprognostic (1.06e-1)" "prognostic favorable (8.08e-5)" "unprognostic (3.50e-1)" "unprognostic (6.50e-2)" "unprognostic (1.43e-3)" "unprognostic (3.91e-1)" "unprognostic (5.09e-2)" "prognostic unfavorable (6.53e-4)" "unprognostic (1.16e-1)" "unprognostic (4.06e-3)" "unprognostic (1.50e-1)" "unprognostic (1.16e-1)" "unprognostic (4.58e-1)" "unprognostic (9.52e-3)" RPH3AL Noc2 ENSG00000181031 "Rabphilin 3A like (without C2 domains)" Q9UNE2 17 212389-386254 "Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 51.0;pituitary gland: 43.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 32.0;Alveolar cells type 2: 34.4;Hepatocytes: 40.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA024311 Approved NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 68: Non-specific - Protein processing" "Cluster 49: Hindbrain - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 72: Alveolar cells - Lung function" 9 "HPA024311: AB_1856429" "unprognostic (4.55e-2)" "unprognostic (1.66e-1)" "unprognostic (3.85e-2)" "unprognostic (9.43e-3)" "unprognostic (8.40e-2)" "unprognostic (1.39e-1)" "unprognostic (2.54e-1)" "unprognostic (1.14e-1)" "unprognostic (6.71e-2)" "unprognostic (1.02e-1)" "unprognostic (2.24e-3)" "unprognostic (1.33e-2)" "prognostic favorable (1.03e-8)" "unprognostic (9.10e-2)" "unprognostic (1.63e-2)" "unprognostic (4.14e-1)" "unprognostic (3.59e-3)" RPP25 FLJ20374 ENSG00000178718 "Ribonuclease P and MRP subunit p25" Q9BUL9 15 74954418-74956772 "Predicted intracellular proteins" "rRNA processing, tRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 90.7;Hofbauer cells: 69.2;Rod photoreceptor cells: 59.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 25.9" "Group enriched" "Detected in many" 5 "dendritic cells: 25.9;monocytes: 10.1" "Low cancer specificity" "Detected in all" "Heart muscle - Fibroblasts, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "olfactory bulb: 30.7" HPA046900 Approved Supported "Nucleoplasm,Centriolar satellite" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 64: Neuronal - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 66: Photoreceptor cells - Visual perception" 25 Nucleoplasm "Centriolar satellite" "HPA046900: AB_10962049" "unprognostic (9.36e-2)" "unprognostic (7.17e-3)" "unprognostic (5.54e-2)" "unprognostic (2.27e-1)" "prognostic unfavorable (2.24e-5)" "unprognostic (7.18e-2)" "unprognostic (5.73e-3)" "unprognostic (5.50e-3)" "unprognostic (7.78e-2)" "unprognostic (1.44e-1)" "unprognostic (3.58e-2)" "unprognostic (1.70e-1)" "unprognostic (4.71e-3)" "unprognostic (5.50e-3)" "unprognostic (5.58e-2)" "unprognostic (1.10e-1)" "unprognostic (2.53e-1)" RSPO4 "C20orf182, dJ824F16.3" ENSG00000101282 "R-spondin 4" Q2I0M5 20 958452-1002311 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Sensory transduction, Wnt signaling pathway" Heparin-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.8;lung: 12.2" "Cell type enhanced" "Detected in some" "Astrocytes: 10.2;Early spermatids: 5.0;Late spermatids: 7.5;Oligodendrocyte precursor cells: 8.0;Oligodendrocytes: 6.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 6.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 8.8" "Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in single" "basal ganglia: 1.2" "Not detected" "Not detected" HPA048887 Uncertain "Secreted in other tissues" Other NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 76: Oligodendrocyte precursor - Unknown function" 11 "HPA048887: AB_2680545" "unprognostic (2.36e-1)" "unprognostic (3.60e-3)" "unprognostic (2.88e-2)" "prognostic unfavorable (2.98e-6)" "unprognostic (8.93e-2)" "unprognostic (1.14e-3)" "unprognostic (1.05e-2)" "unprognostic (1.47e-1)" "unprognostic (6.50e-2)" "unprognostic (2.02e-2)" "unprognostic (5.26e-3)" "unprognostic (2.96e-1)" "unprognostic (5.68e-9)" "unprognostic (6.65e-3)" "unprognostic (4.41e-2)" "unprognostic (6.18e-3)" "unprognostic (2.22e-2)" RXRG "NR2B3, RXR-gamma, RXRgamma" ENSG00000143171 "Retinoid X receptor gamma" P48443 1 165400922-165445355 "Cancer-related genes, FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 29.1;retina: 23.5;skeletal muscle: 47.9" "Group enriched" "Detected in some" 4 "Cone photoreceptor cells: 86.7;Melanocytes: 42.9" "Group enriched" "Detected in many" 13 "melanoma: 25.7;thyroid cancer: 34.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "skin cancer: 29.7" "Colon - Enteric glia cells, Pancreas - Beta cells, Skeletal muscle - Skeletal myocytes, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Region enriched" "Detected in many" 5 "basal ganglia: 100.2" "Low region specificity" "Detected in many" "CAB002615, HPA012933" Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 3: Non-specific - Unknown function" "Cluster 49: Hindbrain - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" 13 "Nucleoplasm, Nuclear bodies" "CAB002615: , HPA012933: AB_2732406" "unprognostic (2.29e-1)" "unprognostic (1.08e-2)" "unprognostic (1.51e-1)" "unprognostic (1.66e-1)" "unprognostic (4.29e-2)" "unprognostic (6.19e-2)" "unprognostic (1.35e-1)" "unprognostic (1.05e-2)" "unprognostic (9.13e-2)" "unprognostic (6.86e-2)" "unprognostic (2.95e-2)" "unprognostic (5.41e-3)" "unprognostic (2.52e-2)" "unprognostic (6.12e-3)" "unprognostic (1.18e-1)" "prognostic favorable (9.40e-5)" "unprognostic (5.03e-2)" SAMD5 dJ875H10.1 ENSG00000203727 "Sterile alpha motif domain containing 5" Q5TGI4 6 147508690-147737547 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 90.0;Inhibitory neurons: 266.6;Squamous epithelial cells: 49.4;Suprabasal keratinocytes: 62.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Skeletal muscle - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067811 Uncertain Supported Vesicles No No "Cluster 39: Retina & Testis - Cilium" "Cluster 49: Hindbrain - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 8: Neurons - Neuronal signaling" Vesicles "HPA067811: AB_2685901" "unprognostic (4.16e-2)" "unprognostic (4.52e-2)" "unprognostic (9.65e-3)" "unprognostic (1.41e-2)" "unprognostic (1.82e-2)" "unprognostic (5.88e-2)" "prognostic unfavorable (2.23e-4)" "unprognostic (2.31e-1)" "unprognostic (1.54e-1)" "unprognostic (1.61e-2)" "unprognostic (8.55e-3)" "unprognostic (3.09e-2)" "unprognostic (5.40e-3)" "unprognostic (1.72e-1)" "unprognostic (4.51e-2)" "unprognostic (9.82e-3)" "unprognostic (1.50e-1)" SC5D SC5DL ENSG00000109929 Sterol-C5-desaturase O75845 11 121292681-121313410 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 381.7" "Cell type enhanced" "Detected in all" "Hepatocytes: 296.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066283, HPA070248" Enhanced Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Cytosol" No No "Cluster 30: Non-specific - DNA binding" "Cluster 69: Liver - Oxidoreductase activity" "Cluster 49: Hindbrain - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 62: Hepatocytes - Metabolism" "Nucleoplasm, Endoplasmic reticulum" "Plasma membrane, Cytosol" "HPA066283: AB_2685648, HPA070248: AB_2686240" "unprognostic (4.78e-2)" "unprognostic (7.29e-2)" "unprognostic (2.26e-2)" "unprognostic (2.36e-1)" "unprognostic (3.98e-2)" "prognostic unfavorable (3.30e-4)" "unprognostic (2.79e-2)" "unprognostic (7.96e-2)" "prognostic unfavorable (3.98e-4)" "unprognostic (4.03e-2)" "unprognostic (3.18e-2)" "unprognostic (1.01e-1)" "prognostic favorable (1.07e-7)" "unprognostic (4.29e-2)" "unprognostic (2.51e-1)" "unprognostic (2.29e-1)" "unprognostic (1.98e-1)" SDK2 "FLJ10832, KIAA1514" ENSG00000069188 "Sidekick cell adhesion molecule 2" Q58EX2 17 73334384-73644445 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 5.3;testis: 9.4" "Cell type enhanced" "Detected in many" "Early spermatids: 16.0;Excitatory neurons: 18.2;Extravillous trophoblasts: 18.7;Late spermatids: 16.9;Oocytes: 16.2;Syncytiotrophoblasts: 14.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 5.7;testis cancer: 6.6" "Colon - Enteric glia cells, Liver - Hepatic stellate cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA 5300000 "Cluster 30: Non-specific - DNA binding" "Cluster 74: Spermatids - Flagellum assembly" "Cluster 49: Hindbrain - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 34: Neurons - Neuronal signaling" 1 "unprognostic (7.22e-4)" "unprognostic (5.57e-2)" "unprognostic (1.70e-1)" "unprognostic (7.00e-3)" "unprognostic (1.62e-2)" "unprognostic (3.18e-1)" "unprognostic (3.16e-1)" "unprognostic (1.15e-1)" "unprognostic (1.98e-1)" "unprognostic (1.49e-1)" "unprognostic (8.80e-4)" "unprognostic (7.69e-2)" "unprognostic (3.89e-2)" "unprognostic (1.44e-2)" "unprognostic (1.38e-1)" "unprognostic (1.37e-2)" "unprognostic (6.64e-2)" SEC14L6 ENSG00000214491 "SEC14 like lipid binding 6" B5MCN3 22 30522799-30546741 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "epididymis: 14.2;parathyroid gland: 20.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 11.1;Alveolar cells type 2: 9.1;Cholangiocytes: 9.5;Collecting duct cells: 13.6;Ductal cells: 7.0;granulocytes: 6.7;Muller glia cells: 15.3" "Cancer enriched" "Detected in many" 7 "renal cancer: 12.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 10 "Kidney cancer: 19.8" "Adipose visceral - Mesothelial cells, Colon - Enteric glia cells, Prostate - Fibroblasts, Skin - Sebaceous gland cells, Testis - Sertoli cells" HPA067695 Approved Nucleoplasm NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 49: Hindbrain - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 72: Alveolar cells - Lung function" Nucleoplasm "HPA067695: AB_2685889" "unprognostic (3.49e-2)" "unprognostic (4.76e-2)" "unprognostic (4.79e-2)" "unprognostic (4.09e-2)" "unprognostic (3.04e-2)" "unprognostic (1.12e-1)" "unprognostic (7.28e-3)" "unprognostic (3.88e-2)" "unprognostic (3.13e-1)" "unprognostic (3.35e-1)" "unprognostic (1.29e-1)" "unprognostic (9.25e-2)" "unprognostic (8.69e-2)" "unprognostic (8.20e-2)" "unprognostic (2.12e-1)" "unprognostic (2.48e-2)" "unprognostic (6.02e-2)" SEMA3C "SEMAE, SemE" ENSG00000075223 "Semaphorin 3C" Q99985 7 80742538-80922359 "Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 89.2;Breast myoepithelial cells: 93.5;Melanocytes: 109.9;Oligodendrocytes: 208.1;Salivary duct cells: 96.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 9 "basophil: 49.7" "Lineage enriched" "Detected in many" 9 "granulocytes: 49.7" "Low cancer specificity" "Detected in all" "Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA042418 Approved "Golgi apparatus,Plasma membrane,Cytosol" "Secreted in other tissues" "Developmental protein" NA NA 13000 "Cluster 46: Basophils - Proteolysis" "Cluster 62: Connective tissue - ECM organization" "Cluster 49: Hindbrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "Golgi apparatus, Cytosol" "Plasma membrane" "HPA042418: AB_10797389" "unprognostic (1.93e-2)" "unprognostic (2.54e-3)" "unprognostic (4.94e-1)" "unprognostic (9.86e-2)" "unprognostic (6.74e-2)" "prognostic unfavorable (5.72e-5)" "unprognostic (9.28e-3)" "unprognostic (1.91e-3)" "unprognostic (1.39e-2)" "unprognostic (9.01e-2)" "prognostic unfavorable (4.08e-5)" "unprognostic (2.07e-2)" "unprognostic (1.55e-3)" "unprognostic (1.78e-2)" "unprognostic (1.57e-1)" "unprognostic (1.37e-2)" "unprognostic (1.92e-2)" SERPINB8 "CAP2, PI8" ENSG00000166401 "Serpin family B member 8" P50452 18 63970029-64019779 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 56.9" "Cell type enhanced" "Detected in many" "monocytes: 69.8;Suprabasal keratinocytes: 59.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB034300 Enhanced Approved Nucleoplasm,Cytosol NA NA 920000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 13: Skin - Cornification" "Cluster 49: Hindbrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" Nucleoplasm Cytosol "CAB034300: AB_2186486" "unprognostic (8.49e-2)" "unprognostic (4.87e-2)" "unprognostic (4.10e-3)" "unprognostic (2.86e-2)" "unprognostic (1.52e-2)" "unprognostic (7.71e-2)" "unprognostic (4.50e-2)" "unprognostic (2.19e-1)" "unprognostic (2.67e-1)" "unprognostic (2.98e-3)" "unprognostic (6.58e-3)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.31e-5)" "unprognostic (8.73e-2)" "unprognostic (3.48e-2)" "unprognostic (1.25e-1)" "unprognostic (1.90e-1)" SIGIRR "IL-1R8, TIR8" ENSG00000185187 "Single Ig and TIR domain containing" Q6IA17 11 405716-417455 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 427.9;Proximal tubular cells: 607.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023188 Approved Approved "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 47: Spleen - Immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 1 "Nucleoli fibrillar center, Cytosol" "HPA023188: AB_1856856" "unprognostic (6.21e-3)" "prognostic favorable (7.44e-5)" "unprognostic (7.30e-2)" "prognostic favorable (1.34e-5)" "unprognostic (6.85e-2)" "prognostic favorable (9.08e-4)" "unprognostic (4.03e-1)" "unprognostic (1.39e-2)" "unprognostic (8.44e-2)" "unprognostic (1.67e-1)" "unprognostic (2.32e-2)" "unprognostic (1.31e-1)" "prognostic favorable (7.61e-6)" "unprognostic (1.00e-3)" "unprognostic (1.76e-1)" "unprognostic (7.63e-2)" "prognostic favorable (1.54e-5)" SIPA1L2 "KIAA1389, SPAR2" ENSG00000116991 "Signal induced proliferation associated 1 like 2" Q9P2F8 1 232397965-232630571 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 175.3;Schwann cells: 105.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024181, HPA027224" Approved Approved "Nucleoplasm,Nuclear membrane,Nuclear bodies,Golgi apparatus" No NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 30: Heart muscle - Heart development" "Cluster 49: Hindbrain - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 12: Squamous epithelial cells - Keratinization" "Nucleoplasm, Nuclear membrane, Nuclear bodies" "Golgi apparatus" "HPA024181: AB_1856886, HPA027224: AB_2672165" "unprognostic (2.34e-2)" "unprognostic (9.67e-2)" "unprognostic (8.02e-2)" "unprognostic (1.71e-3)" "unprognostic (2.98e-1)" "unprognostic (5.68e-2)" "unprognostic (5.57e-3)" "unprognostic (7.79e-2)" "unprognostic (1.60e-1)" "unprognostic (1.80e-2)" "unprognostic (3.77e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (8.15e-4)" "unprognostic (3.36e-2)" "unprognostic (2.75e-1)" "unprognostic (5.84e-3)" "unprognostic (3.45e-3)" SLC17A6 "DNPI, VGLUT2" ENSG00000091664 "Solute carrier family 17 member 6" Q9P2U8 11 22338381-22379503 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Neurotransmitter transport, Phosphate transport, Sodium transport, Symport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 15.3;pituitary gland: 3.5;retina: 7.6" "Group enriched" "Detected in some" 4 "Excitatory neurons: 14.0;Horizontal cells: 17.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 1.6;skin cancer: 1.1" "Pancreas - Beta cells" "Group enriched" "Detected in all" 5 "basal ganglia: 51.9;hypothalamus: 139.9;midbrain: 172.4;pons and medulla: 86.5;thalamus: 165.0" "Low region specificity" "Detected in all" "CAB037130, HPA039226, CAB078204" Supported Supported NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 49: Hindbrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" "CAB037130: AB_477611, CAB078204: AB_2665794, HPA039226: AB_2676400" "unprognostic (1.39e-1)" "unprognostic (1.93e-1)" SLC1A5 "AAAT, ASCT2, M7V1, RDRC" ENSG00000105281 "Solute carrier family 1 member 5" Q15758 19 46774883-46788594 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Antiport, Host-virus interaction, Symport, Transport" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 96.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035239, HPA035240" Enhanced Enhanced "Plasma membrane" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 49: Hindbrain - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 80: Non-specific - Transcription" 1 "Plasma membrane" "HPA035239: AB_10670587, HPA035240: AB_10604092" "unprognostic (8.26e-3)" "unprognostic (6.38e-2)" "unprognostic (7.24e-2)" "unprognostic (7.94e-2)" "unprognostic (2.32e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (1.66e-8)" "unprognostic (2.08e-1)" "unprognostic (1.06e-2)" "unprognostic (9.82e-2)" "unprognostic (9.40e-3)" "unprognostic (9.57e-3)" "prognostic unfavorable (1.18e-7)" "unprognostic (1.28e-2)" "unprognostic (6.30e-2)" "unprognostic (1.06e-2)" "unprognostic (9.83e-2)" SLC7A1 "ATRC1, CAT-1, ERR, HCAT1, REC1L" ENSG00000139514 "Solute carrier family 7 member 1" P30825 13 29509414-29595688 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 53.5" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 227.1;Microglial cells: 154.8;Squamous epithelial cells: 155.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039721, HPA077838" Approved NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 49: Hindbrain - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 12: Squamous epithelial cells - Keratinization" 47 "HPA039721: AB_10672893, HPA077838: " "unprognostic (1.85e-1)" "unprognostic (1.04e-3)" "unprognostic (1.26e-1)" "unprognostic (1.96e-1)" "unprognostic (3.95e-3)" "unprognostic (2.43e-2)" "unprognostic (1.36e-3)" "unprognostic (2.02e-3)" "unprognostic (4.98e-2)" "unprognostic (1.23e-2)" "unprognostic (7.45e-2)" "unprognostic (9.14e-2)" "prognostic unfavorable (1.32e-5)" "unprognostic (3.20e-2)" "unprognostic (3.02e-1)" "unprognostic (1.19e-1)" "unprognostic (7.37e-3)" SLFN11 FLJ34922 ENSG00000172716 "Schlafen family member 11" Q7Z7L1 17 35350305-35373701 "Predicted intracellular proteins" "Antiviral defense, DNA damage, Immunity" "Helicase, Hydrolase, RNA-binding, tRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 66.9;dendritic cells: 72.2;Kupffer cells: 41.9;Langerhans cells: 52.1;Macrophages: 52.9;monocytes: 74.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Colon - Endothelial cells, Skin - Endothelial cells" "HPA023030, HPA062062" Uncertain Supported Nucleoplasm,Cytosol No NA "Cluster 13: Non-specific - Mitochondria" "Cluster 53: Non-specific - Glycosylation" "Cluster 49: Hindbrain - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" Nucleoplasm Cytosol "HPA023030: AB_1856613, HPA062062: AB_2684673" "unprognostic (1.93e-2)" "unprognostic (2.56e-1)" "unprognostic (3.04e-2)" "unprognostic (1.03e-2)" "unprognostic (3.48e-3)" "unprognostic (1.01e-1)" "unprognostic (5.19e-2)" "unprognostic (1.31e-1)" "unprognostic (1.34e-1)" "unprognostic (1.08e-1)" "unprognostic (1.39e-1)" "unprognostic (2.54e-1)" "prognostic unfavorable (9.93e-10)" "unprognostic (1.65e-1)" "unprognostic (5.71e-3)" "unprognostic (6.33e-2)" "unprognostic (8.81e-3)" SMIM1 Vel ENSG00000235169 "Small integral membrane protein 1 (Vel blood group)" B2RUZ4 1 3772749-3775982 "Blood group antigen proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 31.6;heart muscle: 38.9;testis: 41.1" "Cell type enhanced" "Detected in many" "Distal tubular cells: 86.1;Erythroid cells: 290.3;granulocytes: 87.1;Proximal tubular cells: 223.9;Sertoli cells: 103.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "eosinophil: 48.7" "Lineage enriched" "Detected in many" 12 "granulocytes: 48.7" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Eccrine sweat gland cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA069088 Enhanced NA NA 340000 "Cluster 22: Eosinophils - Transcription" "Cluster 4: Testis - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 1: Erythroid cells - Oxygen transport" 48 "HPA069088: AB_2686080" "unprognostic (9.50e-3)" "unprognostic (7.19e-4)" "unprognostic (5.40e-2)" "unprognostic (2.10e-2)" "unprognostic (2.50e-3)" "unprognostic (3.25e-1)" "unprognostic (2.63e-3)" "unprognostic (2.13e-2)" "unprognostic (2.31e-2)" "unprognostic (9.85e-2)" "unprognostic (2.90e-1)" "unprognostic (1.87e-1)" "unprognostic (2.25e-2)" "unprognostic (7.10e-2)" "unprognostic (2.91e-2)" "unprognostic (5.56e-2)" "unprognostic (1.32e-2)" SNTG2 "G2SYN, SYN5" ENSG00000172554 "Syntrophin gamma 2" Q9NY99 2 950849-1367613 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Early spermatids: 45.6;Excitatory neurons: 23.5;Horizontal cells: 21.4;Late spermatids: 57.0;Spermatocytes: 19.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.2" "Colon - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "HPA065258, HPA077904" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 49: Hindbrain - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 11: Late spermatids - Unknown function" 1 "Plasma membrane" Nucleoplasm "HPA065258: , HPA077904: " "unprognostic (7.52e-3)" "unprognostic (7.52e-4)" "unprognostic (4.15e-1)" "unprognostic (3.50e-2)" "unprognostic (2.52e-2)" "unprognostic (1.39e-3)" "unprognostic (2.46e-3)" "unprognostic (2.05e-1)" "unprognostic (2.23e-1)" "unprognostic (3.26e-2)" "unprognostic (7.87e-3)" "unprognostic (3.58e-3)" "unprognostic (3.64e-1)" "unprognostic (2.52e-1)" "unprognostic (1.77e-2)" "unprognostic (5.05e-2)" SP6 "Epfn, KLF14" ENSG00000189120 "Sp6 transcription factor" Q3SY56 17 47844908-47855874 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 22.1;skin 1: 14.1" "Group enriched" "Detected in many" 4 "Basal prostatic cells: 23.1;Cytotrophoblasts: 54.8;Syncytiotrophoblasts: 86.1" "Cancer enhanced" "Detected in many" "urothelial cancer: 11.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 33.9;colorectal cancer: 22.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA024516, HPA044469" Supported "Nucleoplasm,Mitotic spindle,Centrosome" Yes No "Cluster 58: Placenta - Pregnancy" "Cluster 49: Hindbrain - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 24: Cytotrophoblasts - Mitochondria" 9 Nucleoplasm "Mitotic spindle, Centrosome" "HPA024516: AB_10960551, HPA044469: AB_10966430" "unprognostic (3.06e-2)" "unprognostic (4.32e-2)" "unprognostic (1.07e-2)" "unprognostic (7.55e-3)" "unprognostic (6.79e-2)" "unprognostic (4.57e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (2.11e-6)" "unprognostic (1.22e-1)" "unprognostic (8.72e-2)" "unprognostic (3.92e-3)" "unprognostic (1.63e-1)" "unprognostic (9.59e-3)" "prognostic favorable (6.39e-4)" "unprognostic (3.33e-1)" "unprognostic (9.93e-2)" "prognostic favorable (5.72e-4)" SPATC1 "MGC61633, SPATA15, SPERIOLIN" ENSG00000186583 "Spermatogenesis and centriole associated 1" Q76KD6 8 144012280-144047114 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "testis: 36.5" "Cell type enriched" "Detected in some" 8 "Late spermatids: 348.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Testis - Late spermatids" "Not detected" "Not detected" "Region enriched" "Detected in many" 5 "cerebellum: 12.6" NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 49: Hindbrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 36: Late spermatids - Unknown function" "unprognostic (2.96e-1)" "unprognostic (1.41e-3)" "unprognostic (3.34e-1)" "unprognostic (4.18e-2)" "unprognostic (1.65e-1)" "unprognostic (4.59e-3)" "unprognostic (6.96e-2)" "unprognostic (4.30e-2)" "unprognostic (1.49e-2)" "unprognostic (2.77e-1)" "unprognostic (4.12e-2)" "unprognostic (4.39e-2)" "unprognostic (1.34e-3)" "unprognostic (2.74e-1)" "unprognostic (5.81e-3)" "unprognostic (2.19e-1)" "unprognostic (2.74e-1)" SPNS2 SLC63A2 ENSG00000183018 "Sphingolipid transporter 2" Q8IVW8 17 4498881-4539035 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 49.6" "Cell type enhanced" "Detected in many" "Adipocytes: 35.6;Endothelial cells: 40.1;Extravillous trophoblasts: 35.1;Gastric mucus-secreting cells: 31.8;Microglial cells: 35.8;Oligodendrocytes: 91.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Endothelial cells, Heart muscle - Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Keratinocyte (granular), Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068717 Uncertain NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 49: Hindbrain - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "HPA068717: AB_2686021" "unprognostic (3.03e-2)" "unprognostic (4.76e-2)" "unprognostic (8.08e-2)" "unprognostic (3.53e-2)" "unprognostic (2.78e-1)" "unprognostic (6.30e-3)" "unprognostic (1.10e-3)" "unprognostic (2.33e-1)" "unprognostic (1.70e-1)" "unprognostic (1.63e-3)" "unprognostic (2.99e-2)" "unprognostic (2.98e-2)" "unprognostic (4.48e-2)" "unprognostic (2.20e-2)" "unprognostic (1.68e-1)" "unprognostic (2.19e-2)" "unprognostic (6.89e-2)" SPOCK2 "KIAA0275, testican-2" ENSG00000107742 "SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2" Q92563 10 72059034-72089032 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 223.2;lymphoid tissue: 111.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 623.7;Bipolar cells: 105.1;Horizontal cells: 103.9;NK-cells: 129.9;Sertoli cells: 149.6;T-cells: 213.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 45.9;MAIT T-cell: 79.8;memory CD4 T-cell: 46.3;memory CD8 T-cell: 36.1;naive CD4 T-cell: 37.9;naive CD8 T-cell: 39.9;T-reg: 63.3" "Lineage enriched" "Detected in many" 8 "T-cells: 79.8" "Cancer enhanced" "Detected in many" "ovarian cancer: 140.6;Uterine cancer: 69.7" "Colon - Colon enteroendocrine cells, Kidney - Podocytes, Liver - T-cells, Lung - Alveolar cells type 1, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044605 Enhanced "Secreted to blood" "No annotated function" NA NA 34000 "Cluster 11: T-cells - Unknown function" "Cluster 65: Cerebellum - Nervous system development" "Cluster 49: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 1 "HPA044605: AB_10965991" "prognostic favorable (4.05e-4)" "unprognostic (3.11e-3)" "unprognostic (2.92e-2)" "unprognostic (2.29e-1)" "unprognostic (2.77e-2)" "prognostic favorable (1.95e-5)" "unprognostic (4.18e-2)" "unprognostic (9.04e-2)" "prognostic favorable (4.72e-4)" "prognostic unfavorable (7.19e-4)" "unprognostic (4.53e-3)" "unprognostic (2.29e-1)" "unprognostic (1.46e-3)" "unprognostic (5.59e-2)" "unprognostic (5.49e-2)" "unprognostic (3.19e-3)" "unprognostic (2.24e-2)" ST8SIA2 "HsT19690, SIAT8B, ST8SIA-II, STX" ENSG00000140557 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2" Q92186 15 92393881-92468728 "Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 3.7;lymphoid tissue: 1.7" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 2.6;Cardiomyocytes: 3.5;Horizontal cells: 1.9;Inhibitory neurons: 3.3;Muller glia cells: 1.8" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "pons: 18.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Myeloma: 7.8;Neuroblastoma: 18.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA054518, HPA057819" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Intracellular and membrane" Enzyme NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 49: Hindbrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 10: Muller glia cells - Visual perception" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA054518: AB_2682514, HPA057819: " "unprognostic (4.70e-2)" "unprognostic (2.48e-2)" "unprognostic (1.26e-1)" "unprognostic (9.32e-3)" "unprognostic (1.03e-1)" "unprognostic (2.87e-2)" "unprognostic (2.32e-1)" "unprognostic (1.28e-5)" "unprognostic (3.91e-2)" "unprognostic (5.39e-3)" "unprognostic (1.59e-2)" "unprognostic (4.44e-3)" "unprognostic (4.78e-2)" "unprognostic (2.29e-1)" "unprognostic (3.16e-1)" "unprognostic (3.00e-1)" ST8SIA4 "PST, PST1, SIAT8D" ENSG00000113532 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4" Q92187 5 100806933-100903282 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 13.6" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 70.5;Kupffer cells: 75.0;Langerhans cells: 176.6;Microglial cells: 96.6;monocytes: 96.0;Schwann cells: 99.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 91.9" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 10.5;lymphoma: 14.1;Myeloma: 17.3" "Breast - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA036437, HPA051126, HPA053995" Approved Supported "Golgi apparatus" "Intracellular and membrane" Enzyme NA NA 980000 "Cluster 35: Neutrophils - Protein binding" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 28: Dendritic cells - Antigen presentation" "Golgi apparatus" "HPA036437: , HPA051126: AB_2681352, HPA053995: AB_2682336" "unprognostic (2.25e-1)" "unprognostic (2.04e-2)" "unprognostic (1.04e-1)" "unprognostic (1.98e-2)" "unprognostic (1.14e-1)" "unprognostic (6.45e-3)" "unprognostic (1.91e-1)" "unprognostic (5.46e-2)" "unprognostic (2.87e-1)" "unprognostic (1.49e-2)" "unprognostic (1.71e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (7.80e-7)" "unprognostic (6.07e-2)" "unprognostic (4.38e-2)" "unprognostic (1.30e-1)" "unprognostic (1.23e-2)" STBD1 "FLJ41801, GENX-3414" ENSG00000118804 "Starch binding domain 1" O95210 4 76306733-76311130 "Plasma proteins, Predicted intracellular proteins, Transporters" "Autophagy, Carbohydrate metabolism, Glycogen metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 126.4;skeletal muscle: 239.8;tongue: 148.6" "Cell type enhanced" "Detected in some" "Ductal cells: 5.2;Glandular and luminal cells: 3.9;Plasma cells: 5.0;Proximal enterocytes: 10.5;Skeletal myocytes: 4.9;Smooth muscle cells: 3.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA011952, HPA012849" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 32: Smooth muscle cells - Muscle contraction" 5 "Endoplasmic reticulum" "HPA011952: AB_1847461, HPA012849: AB_1847460" "unprognostic (1.46e-1)" "unprognostic (1.02e-3)" "unprognostic (4.29e-2)" "unprognostic (1.95e-1)" "unprognostic (2.57e-1)" "unprognostic (4.72e-2)" "unprognostic (1.35e-2)" "unprognostic (6.84e-2)" "unprognostic (3.06e-1)" "unprognostic (1.03e-1)" "unprognostic (4.96e-3)" "unprognostic (4.42e-2)" "unprognostic (3.52e-2)" "unprognostic (2.93e-1)" "unprognostic (2.00e-1)" "unprognostic (2.84e-1)" "unprognostic (5.74e-2)" STEAP3 "dudlin-2, STMP3, TSAP6" ENSG00000115107 "STEAP3 metalloreductase" Q658P3 2 119223831-119265652 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Apoptosis, Cell cycle, Ion transport, Iron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 184.9;parathyroid gland: 76.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 75.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.4;intermediate monocyte: 2.7;myeloid DC: 4.1;NK-cell: 1.3" "Group enriched" "Detected in many" 6 "dendritic cells: 4.1;monocytes: 2.7;NK-cells: 1.3" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA050510 Approved Approved Nucleoli,Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 62: Hepatocytes - Metabolism" 1 Cytosol Nucleoli "HPA050510: AB_2681151" "unprognostic (6.51e-2)" "unprognostic (6.48e-2)" "unprognostic (4.89e-2)" "unprognostic (3.45e-2)" "unprognostic (1.94e-3)" "unprognostic (9.07e-2)" "unprognostic (1.99e-2)" "unprognostic (3.04e-1)" "unprognostic (9.75e-2)" "unprognostic (1.58e-3)" "unprognostic (5.08e-3)" "unprognostic (6.95e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.82e-1)" "unprognostic (4.45e-1)" "unprognostic (9.37e-2)" "unprognostic (6.82e-2)" SULF2 "HSULF-2, KIAA1247, SULF-2" ENSG00000196562 "Sulfatase 2" Q8IWU5 20 47656197-47786616 "Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 135.0;Endometrial stromal cells: 207.4;Granulosa cells: 208.0;Oligodendrocyte precursor cells: 232.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "basophil: 22.2;classical monocyte: 17.3;intermediate monocyte: 15.7;myeloid DC: 19.5;neutrophil: 26.4;non-classical monocyte: 8.7;plasmacytoid DC: 25.6" "Group enriched" "Detected in many" 78 "dendritic cells: 25.6;granulocytes: 26.4;monocytes: 17.3" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Heart muscle - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002325 Approved "Intracellular and membrane" Enzyme NA NA 340000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 62: Connective tissue - ECM organization" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 9: Endometrial stromal cells - Transcription" "HPA002325: AB_1080126" "unprognostic (4.06e-2)" "prognostic unfavorable (6.43e-5)" "unprognostic (4.39e-1)" "unprognostic (8.99e-2)" "unprognostic (2.65e-1)" "unprognostic (9.08e-2)" "unprognostic (1.87e-1)" "unprognostic (2.48e-2)" "unprognostic (1.81e-2)" "unprognostic (3.04e-2)" "unprognostic (1.53e-3)" "unprognostic (1.85e-1)" "prognostic unfavorable (4.02e-4)" "unprognostic (7.83e-2)" "unprognostic (1.14e-1)" "unprognostic (1.09e-1)" "unprognostic (7.14e-3)" TDRD9 "C14orf75, DKFZp434N0820, FLJ36164, NET54" ENSG00000156414 "Tudor domain containing 9" Q8NDG6 14 103928456-104052667 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Differentiation, Meiosis, RNA-mediated gene silencing, Spermatogenesis" "Developmental protein, Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "parathyroid gland: 27.0;testis: 37.2" "Cell type enhanced" "Detected in many" "Ciliated cells: 23.5;Early spermatids: 15.5;Spermatocytes: 63.7;Spermatogonia: 37.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "classical monocyte: 1.5" "Lineage enriched" "Detected in single" 6 "monocytes: 1.5" "Cancer enhanced" "Detected in many" "cervical cancer: 16.9;thyroid cancer: 7.7" "Lung - Neutrophil_2, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 49: Hindbrain - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 31: Spermatocytes - Spermatogenesis" "unprognostic (3.71e-1)" "unprognostic (3.02e-1)" "unprognostic (1.59e-1)" "unprognostic (1.89e-1)" "unprognostic (1.91e-1)" "unprognostic (1.55e-1)" "unprognostic (2.74e-1)" "unprognostic (3.74e-1)" "unprognostic (1.55e-1)" "unprognostic (1.61e-1)" "unprognostic (2.13e-4)" "unprognostic (1.60e-2)" "unprognostic (4.57e-3)" "unprognostic (8.97e-2)" "unprognostic (3.34e-1)" "prognostic unfavorable (5.52e-4)" "unprognostic (2.41e-2)" TEC PSCTK4 ENSG00000135605 "Tec protein tyrosine kinase" P42680 4 48135783-48269838 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 17.5;granulocytes: 29.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "basophil: 20.8;eosinophil: 13.4" "Lineage enriched" "Detected in many" 6 "granulocytes: 20.8" "Cancer enhanced" "Detected in many" "Myeloma: 12.4" "Adipose subcutaneous - Macrophages, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA005733, HPA024657" Approved Supported "Plasma membrane" NA NA "Cluster 32: Basophils - Transcription" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 49: Hindbrain - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 30: Granulocytes - Unknown function" 1 "Plasma membrane" "HPA005733: AB_1857878, HPA024657: AB_2671637" "unprognostic (7.19e-2)" "unprognostic (1.44e-1)" "unprognostic (1.41e-2)" "unprognostic (4.07e-3)" "unprognostic (4.21e-2)" "unprognostic (8.57e-2)" "unprognostic (3.14e-1)" "unprognostic (1.67e-1)" "unprognostic (8.36e-2)" "prognostic favorable (7.12e-4)" "unprognostic (7.46e-3)" "unprognostic (7.83e-2)" "unprognostic (1.01e-4)" "unprognostic (4.24e-2)" "unprognostic (2.16e-1)" "unprognostic (7.39e-2)" "unprognostic (4.96e-3)" TESMIN "CXCDC2, MTL5" ENSG00000132749 "Testis expressed metallothionein like protein" Q9Y4I5 11 68707440-68751520 "Predicted intracellular proteins" "Differentiation, Meiosis, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "testis: 51.0" "Group enriched" "Detected in many" 4 "Early spermatids: 117.8;Late spermatids: 156.2;Oocytes: 65.4;Spermatocytes: 141.7" "Cancer enhanced" "Detected in many" "breast cancer: 6.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA018539 Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 49: Hindbrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 31: Spermatocytes - Spermatogenesis" Nucleoplasm "Vesicles, Cytosol" "HPA018539: " "unprognostic (1.99e-1)" "unprognostic (3.97e-3)" "unprognostic (1.34e-2)" "prognostic unfavorable (1.75e-5)" "unprognostic (3.22e-2)" "unprognostic (6.71e-2)" "unprognostic (1.76e-2)" "unprognostic (6.99e-3)" "unprognostic (2.54e-1)" "unprognostic (5.33e-2)" "unprognostic (2.19e-2)" "unprognostic (8.47e-2)" "unprognostic (5.27e-2)" "unprognostic (6.39e-2)" "unprognostic (2.99e-1)" "unprognostic (9.85e-2)" "unprognostic (3.17e-1)" THOC6 "fSAP35, MGC2655, WDR58" ENSG00000131652 "THO complex subunit 6" Q86W42 16 3024027-3027755 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, mRNA processing, mRNA splicing, mRNA transport, Transport" "Developmental protein, RNA-binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 114.0;Extravillous trophoblasts: 124.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052953 Uncertain Supported "Nucleoplasm,Nuclear speckles" No No "Cluster 13: Non-specific - Mitochondria" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 4: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Nuclear speckles" "HPA052953: AB_2681997" "unprognostic (2.07e-2)" "unprognostic (4.13e-3)" "unprognostic (1.70e-1)" "unprognostic (2.04e-1)" "unprognostic (2.08e-1)" "unprognostic (2.91e-1)" "unprognostic (7.82e-3)" "unprognostic (1.81e-1)" "unprognostic (1.31e-1)" "unprognostic (2.20e-2)" "unprognostic (5.15e-2)" "unprognostic (3.44e-2)" "prognostic unfavorable (4.40e-4)" "unprognostic (3.59e-1)" "unprognostic (1.43e-1)" "unprognostic (6.17e-2)" "unprognostic (9.43e-2)" THSD7B KIAA1679 ENSG00000144229 "Thrombospondin type 1 domain containing 7B" Q9C0I4 2 136765545-137677718 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "retina: 18.8" "Cell type enriched" "Detected in some" 4 "Inhibitory neurons: 146.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.4;Rhabdoid: 2.7" "Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA051416, HPA056745" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 76: Retina - Visual perception" "Cluster 49: Hindbrain - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 69: Neurons - Neuronal signaling" 23 Nucleoplasm Cytosol "HPA051416: AB_2681477, HPA056745: AB_2683224" "unprognostic (4.65e-3)" "unprognostic (2.25e-1)" "unprognostic (8.98e-2)" "unprognostic (1.24e-2)" "unprognostic (1.59e-3)" "unprognostic (1.12e-1)" "unprognostic (6.50e-2)" "unprognostic (7.80e-3)" "unprognostic (2.89e-1)" "unprognostic (1.65e-1)" "unprognostic (3.20e-1)" "unprognostic (6.56e-2)" "unprognostic (4.47e-6)" "unprognostic (2.42e-3)" "unprognostic (1.89e-1)" "unprognostic (4.31e-2)" "unprognostic (4.30e-2)" TINAG ENSG00000137251 "Tubulointerstitial nephritis antigen" Q9UJW2 6 54307859-54390142 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "kidney: 106.2" "Group enriched" "Detected in some" 5 "Distal enterocytes: 45.8;Proximal enterocytes: 70.4;Proximal tubular cells: 161.1" "Cancer enriched" "Detected in some" 4 "renal cancer: 15.8" "Region enhanced" "Detected in some" "pons: 4.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 12.4" "Colon - Colon enterocytes, Kidney - Proximal tubular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA035427, HPA073753" Approved "Secreted to extracellular matrix" "Cell adhesion" NA NA 40000 "Cluster 52: Kidney - Transmembrane transport" "Cluster 49: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Proximal tubular cells - Transmembrane transport" "HPA035427: AB_10601822, HPA073753: " "unprognostic (7.62e-3)" "unprognostic (1.12e-2)" "prognostic unfavorable (2.05e-5)" "unprognostic (7.27e-2)" "unprognostic (5.99e-3)" "prognostic favorable (8.75e-5)" "unprognostic (7.10e-2)" TLL2 ENSG00000095587 "Tolloid like 2" Q9Y6L7 10 96364608-96513926 "Predicted secreted proteins" Differentiation "Developmental protein, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.6;heart muscle: 3.5;tongue: 1.8" "Cell type enhanced" "Detected in some" "Early spermatids: 7.4;Granulosa cells: 5.2;Inhibitory neurons: 5.4;Late spermatids: 5.1;Oligodendrocytes: 17.4;Pancreatic endocrine cells: 5.1;Schwann cells: 9.7" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Uterine cancer: 4.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted - unknown location" "Developmental protein" NA NA "Cluster 23: Non-specific - Cellular respiration" "Cluster 49: Hindbrain - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 26: Schwann cells & Melanocytes - Mixed function" "unprognostic (1.28e-2)" "unprognostic (7.54e-4)" "unprognostic (1.50e-1)" "unprognostic (3.31e-3)" "unprognostic (2.67e-1)" "unprognostic (2.14e-3)" "unprognostic (1.31e-2)" "unprognostic (3.52e-4)" "unprognostic (7.08e-2)" "unprognostic (2.50e-1)" "unprognostic (6.71e-2)" "unprognostic (3.37e-2)" "unprognostic (4.98e-4)" "unprognostic (2.90e-1)" "unprognostic (8.41e-2)" "unprognostic (1.95e-4)" "unprognostic (2.30e-1)" TMEM120A "NET29, TACAN, TMPIT" ENSG00000189077 "Transmembrane protein 120A" Q9BXJ8 7 75986831-75994656 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 241.8;Late spermatids: 1002.8;Proximal enterocytes: 421.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 223.9" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 49: Hindbrain - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 36: Late spermatids - Unknown function" 21 "unprognostic (1.78e-2)" "unprognostic (3.35e-2)" "unprognostic (1.71e-2)" "unprognostic (4.03e-2)" "unprognostic (1.00e-1)" "unprognostic (1.99e-1)" "unprognostic (3.26e-1)" "unprognostic (2.75e-3)" "unprognostic (6.16e-2)" "unprognostic (1.59e-2)" "unprognostic (1.10e-1)" "unprognostic (6.31e-2)" "unprognostic (1.02e-1)" "unprognostic (6.58e-2)" "unprognostic (6.61e-2)" "unprognostic (1.71e-1)" "unprognostic (5.15e-2)" TMEM61 ENSG00000143001 "Transmembrane protein 61" Q8N0U2 1 54980628-54992288 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 23.0;pituitary gland: 46.4;salivary gland: 19.0" "Cell type enhanced" "Detected in many" "Distal tubular cells: 21.5;Enteroendocrine cells: 26.0;Intestinal goblet cells: 63.6;Ionocytes: 42.3;Oocytes: 22.8;Salivary duct cells: 39.7;Serous glandular cells: 22.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 3.4;pancreatic cancer: 3.6" "Adipose subcutaneous - Smooth muscle cells, Pancreas - Beta cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA030614 Uncertain NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 49: Hindbrain - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" 11 "HPA030614: AB_10603216" "unprognostic (7.62e-2)" "unprognostic (1.67e-3)" "prognostic favorable (1.07e-4)" "unprognostic (1.00e-1)" "unprognostic (6.63e-4)" "unprognostic (6.15e-2)" "unprognostic (2.67e-3)" "unprognostic (1.49e-1)" "unprognostic (3.05e-1)" "unprognostic (4.46e-2)" "unprognostic (1.91e-2)" "unprognostic (7.24e-2)" "prognostic favorable (1.78e-7)" "unprognostic (8.47e-2)" "unprognostic (2.20e-2)" "unprognostic (4.01e-2)" "unprognostic (4.62e-3)" TMPRSS11F "FLJ16046, HATL4" ENSG00000198092 "Transmembrane serine protease 11F" Q6ZWK6 4 68053198-68129869 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 14.7;skin 1: 9.0;vagina: 4.7" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 2.7;Cytotrophoblasts: 1.6;Squamous epithelial cells: 7.5;Suprabasal keratinocytes: 8.6" "Group enriched" "Detected in some" 7 "cervical cancer: 1.6;head and neck cancer: 2.1;lung cancer: 0.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 1.1;Leukemia: 1.0;lymphoma: 1.8" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA026911 Uncertain NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 49: Hindbrain - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 59: Suprabasal keratinocytes - Cornification" "HPA026911: AB_2205589" "unprognostic (9.46e-2)" "unprognostic (5.30e-1)" "unprognostic (7.16e-2)" "unprognostic (8.79e-3)" "unprognostic (1.09e-1)" "unprognostic (2.40e-1)" "unprognostic (1.22e-1)" "unprognostic (5.08e-2)" TNIP3 "ABIN-3, FLJ21162, LIND" ENSG00000050730 "TNFAIP3 interacting protein 3" Q96KP6 4 121131408-121227466 "Predicted intracellular proteins" "Inflammatory response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 6.2;urinary bladder: 4.0" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 10.2;Early spermatids: 12.2;Late spermatids: 45.3;Macrophages: 16.4;monocytes: 21.5;T-cells: 16.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD8 T-cell: 6.2" "Lineage enriched" "Detected in single" 10 "T-cells: 6.2" "Cancer enhanced" "Detected in many" "lymphoma: 5.9" "Breast - T-cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA043063 Uncertain NA NA "Cluster 1: T-cells - Unknown function" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 49: Hindbrain - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 29: Monocytes - Innate immune response" 26 "HPA043063: AB_10793989" "unprognostic (2.89e-3)" "unprognostic (2.60e-1)" "unprognostic (5.23e-3)" "unprognostic (8.75e-5)" "unprognostic (9.62e-3)" "unprognostic (2.14e-2)" "unprognostic (1.49e-1)" "unprognostic (2.46e-1)" "unprognostic (2.80e-1)" "unprognostic (3.19e-2)" "unprognostic (2.55e-1)" "unprognostic (9.35e-2)" "unprognostic (2.84e-7)" "unprognostic (3.35e-2)" "unprognostic (6.51e-2)" "unprognostic (3.51e-1)" "unprognostic (8.78e-2)" TOM1 ENSG00000100284 "Target of myb1 membrane trafficking protein" O60784 22 35299275-35347992 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 206.3" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 189.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000818, HPA001749" Approved Approved "Plasma membrane,Centriolar satellite,Cytosol" NA NA 44000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 29: Monocytes - Innate immune response" 2 Cytosol "Plasma membrane, Centriolar satellite" "HPA000818: AB_2666101, HPA001749: AB_1080323" "unprognostic (3.75e-1)" "unprognostic (8.07e-2)" "unprognostic (5.18e-2)" "prognostic favorable (2.20e-5)" "unprognostic (1.11e-2)" "unprognostic (7.55e-2)" "unprognostic (4.07e-3)" "unprognostic (2.24e-1)" "unprognostic (9.92e-2)" "unprognostic (2.32e-1)" "unprognostic (3.71e-1)" "unprognostic (8.16e-2)" "prognostic favorable (3.72e-5)" "unprognostic (1.22e-1)" "unprognostic (1.30e-1)" "unprognostic (7.54e-3)" "unprognostic (3.31e-2)" TOM1L2 ENSG00000175662 "Target of myb1 like 2 membrane trafficking protein" Q6ZVM7 17 17843511-17972422 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 171.2;Oligodendrocytes: 114.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skin - Keratinocyte (granular), Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022541, HPA023304" Enhanced Approved "Golgi apparatus,Intermediate filaments" NA NA 73000 "Cluster 21: Neutrophils - Unknown function" "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 47: Astrocytes - Unknown function" 1 "Golgi apparatus, Intermediate filaments" "HPA022541: AB_1858182, HPA023304: AB_1858183" "unprognostic (2.32e-1)" "unprognostic (7.54e-2)" "unprognostic (1.12e-1)" "unprognostic (2.57e-2)" "unprognostic (3.25e-2)" "prognostic favorable (1.24e-4)" "unprognostic (2.22e-1)" "unprognostic (1.08e-1)" "unprognostic (6.29e-2)" "prognostic unfavorable (2.58e-4)" "prognostic favorable (1.92e-4)" "unprognostic (3.19e-2)" "prognostic favorable (6.21e-9)" "unprognostic (7.11e-2)" "unprognostic (1.40e-1)" "unprognostic (4.18e-2)" "unprognostic (4.51e-2)" TRADD Hs.89862 ENSG00000102871 "TNFRSF1A associated via death domain" Q15628 16 67154185-67159909 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004602, HPA071341" Enhanced Approved Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 47: Spleen - Immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 14: Langerhans cells - Innate immune response" 7 Cytosol "CAB004602: AB_2209061, HPA071341: AB_2732178" "unprognostic (2.66e-1)" "unprognostic (3.11e-1)" "unprognostic (2.23e-2)" "prognostic favorable (1.40e-4)" "unprognostic (1.50e-2)" "unprognostic (1.21e-1)" "unprognostic (5.68e-2)" "unprognostic (4.96e-2)" "unprognostic (4.15e-2)" "unprognostic (2.24e-1)" "unprognostic (2.82e-1)" "unprognostic (8.27e-3)" "unprognostic (1.29e-1)" "unprognostic (1.20e-1)" "unprognostic (1.38e-1)" "unprognostic (7.24e-2)" "unprognostic (1.83e-1)" TRAF2 "RNF117, TRAP3" ENSG00000127191 "TNF receptor associated factor 2" Q12933 9 136881912-136926607 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 58.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004603, HPA009972, HPA010634" Uncertain Enhanced Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 16: Non-specific - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" 237 Cytosol "CAB004603: AB_628389, HPA009972: AB_1080350, HPA010634: AB_1080347" "unprognostic (7.77e-2)" "unprognostic (4.54e-3)" "prognostic unfavorable (9.32e-4)" "unprognostic (1.15e-1)" "unprognostic (1.11e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (3.06e-4)" "unprognostic (4.91e-2)" "unprognostic (7.23e-2)" "unprognostic (4.28e-2)" "unprognostic (7.39e-2)" "unprognostic (2.82e-2)" "prognostic unfavorable (2.09e-4)" "unprognostic (1.80e-3)" "unprognostic (5.52e-2)" "unprognostic (1.60e-1)" "unprognostic (1.53e-2)" TRBV20-1 "TCRBV20S1, TCRBV2S1, TRBV201" ENSG00000211747 "T cell receptor beta variable 20-1" A0A075B6N2 7 142626649-142627399 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 31 "lymphoid tissue: 157.5" "Cell type enriched" "Detected in some" 25 "T-cells: 25.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "pons: 3.5" "Immune cell enhanced" "Detected in many" "T-reg: 355.4" "Lineage enriched" "Detected in many" 115 "T-cells: 355.4" "Cancer enriched" "Detected in some" 79 "Leukemia: 257.8" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Lung - T-cells, Prostate - T-cells, Thyroid - T-cells" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 49: Hindbrain - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 7: T-cells - T-cell receptor" "unprognostic (1.25e-3)" "prognostic favorable (4.40e-5)" "unprognostic (1.39e-2)" "prognostic favorable (8.49e-4)" "unprognostic (8.83e-2)" "unprognostic (2.69e-3)" "unprognostic (4.34e-2)" "unprognostic (8.75e-3)" "prognostic favorable (1.37e-4)" "unprognostic (1.30e-2)" "unprognostic (8.86e-2)" "unprognostic (2.56e-1)" "prognostic unfavorable (1.11e-5)" "unprognostic (1.45e-1)" "unprognostic (1.30e-1)" "unprognostic (1.05e-1)" "unprognostic (3.41e-2)" TRBV20OR9-2 "TCRBV20S2, TCRBV2O, TCRBV2S2O, TRBV20/OR9-2" ENSG00000205274 "T cell receptor beta variable 20/OR9-2 (non-functional)" 9 33617845-33618508 "Predicted intracellular proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "pancreas: 1.0;placenta: 2.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "testis cancer: 1.0" "Region enhanced" "Detected in many" "pons: 23.9" "Group enriched" "Detected in many" 16 "MAIT T-cell: 9.0;memory CD4 T-cell: 9.8;memory CD8 T-cell: 6.3;naive CD4 T-cell: 9.1;naive CD8 T-cell: 6.8;T-reg: 23.4" "Lineage enriched" "Detected in single" 36 "T-cells: 23.4" "Cancer enriched" "Detected in some" 43 "Sarcoma: 48.0" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 49: Hindbrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 24: Cytotrophoblasts - Mitochondria" "unprognostic (1.53e-1)" "unprognostic (3.70e-2)" "unprognostic (3.01e-2)" "unprognostic (1.31e-1)" "unprognostic (1.51e-1)" TRGV8 "TCRGV8, V1S8" ENSG00000211696 "T cell receptor gamma variable 8" A0A0C4DH27 7 38330343-38330935 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 6.7;prostate: 4.7" "Cell type enriched" "Detected in some" 10 "T-cells: 12.0" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 6.8" "Group enriched" "Detected in many" 6 "gdT-cell: 34.5;MAIT T-cell: 40.7;memory CD8 T-cell: 31.1;naive CD8 T-cell: 17.3" "Lineage enriched" "Detected in many" 7 "T-cells: 40.7" "Cancer enriched" "Detected in some" 16 "Leukemia: 20.5" "Adipose visceral - T-cells, Thyroid - T-cells" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 49: Hindbrain - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 7: T-cells - T-cell receptor" TRIM29 "ATDC, FLJ36085" ENSG00000137699 "Tripartite motif containing 29" Q14134 11 120111286-120185529 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 580.7;skin 1: 533.6;vagina: 261.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 442.0;Basal squamous epithelial cells: 302.7;Squamous epithelial cells: 578.0;Suprabasal keratinocytes: 891.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 93.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 203.7;Gallbladder cancer: 155.6;head and neck cancer: 155.4" "Adipose visceral - Mesothelial cells, Breast - Breast myoepithelial cells, Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Testis - Late spermatids" "Not detected" "Not detected" "Region enriched" "Detected in single" 9 "spinal cord: 5.3" "HPA020053, HPA074841" Enhanced Approved "Nucleoplasm,Intermediate filaments,Cytosol" NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 13 "Intermediate filaments" "Nucleoplasm, Cytosol" "HPA020053: AB_1858280, HPA074841: " "unprognostic (1.10e-1)" "unprognostic (6.22e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (2.88e-4)" "unprognostic (9.79e-3)" "unprognostic (3.08e-2)" "unprognostic (3.30e-1)" "unprognostic (5.24e-3)" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (4.46e-4)" "unprognostic (9.37e-2)" "unprognostic (4.29e-3)" "prognostic favorable (4.93e-4)" "unprognostic (2.59e-1)" "unprognostic (2.91e-2)" "unprognostic (4.15e-2)" TRMT2B "CXorf34, FLJ12687" ENSG00000188917 "TRNA methyltransferase 2 homolog B" Q96GJ1 X 101009346-101052116 "Enzymes, Predicted intracellular proteins" "rRNA processing, tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003745, HPA035120, HPA040814" Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 35: Non-specific - Mitochondria" "Cluster 49: Hindbrain - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 55: Non-specific - Transcription" 1 Nucleoplasm "Nuclear bodies" "HPA003745: AB_2667047, HPA035120: AB_10601702, HPA040814: " "prognostic unfavorable (1.58e-5)" "unprognostic (6.72e-3)" "unprognostic (3.28e-1)" "unprognostic (1.54e-2)" "unprognostic (4.44e-1)" "unprognostic (8.74e-2)" "unprognostic (3.52e-2)" "unprognostic (8.16e-3)" "unprognostic (5.77e-2)" "unprognostic (2.01e-1)" "unprognostic (8.80e-2)" "unprognostic (2.78e-2)" "prognostic favorable (2.30e-7)" "unprognostic (4.58e-2)" "unprognostic (4.82e-1)" "unprognostic (5.03e-2)" "unprognostic (1.60e-2)" TSHB ENSG00000134200 "Thyroid stimulating hormone subunit beta" P01222 1 115029826-115034302 "Disease related genes, Human disease related genes, Predicted secreted proteins" Hormone "Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 2636 "pituitary gland: 1711.1" "Group enriched" "Detected in some" 12 "Early spermatids: 1.1;Late spermatids: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hypothalamus: 1.7" "Not detected" "Not detected" "CAB022202, HPA042681, CAB080112" Enhanced "Secreted to blood" Hormone NA NA "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 49: Hindbrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 36: Late spermatids - Unknown function" "CAB022202: , CAB080112: , HPA042681: AB_2732500" "unprognostic (2.14e-4)" "unprognostic (1.37e-1)" "unprognostic (1.73e-1)" TSPAN2 "FLJ12082, TSN2, TSPAN-2" ENSG00000134198 "Tetraspanin 2" O60636 1 115048011-115089503 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 45.8;intestine: 53.5" "Cell type enhanced" "Detected in many" "NK-cells: 29.8;Pancreatic endocrine cells: 73.0;Smooth muscle cells: 22.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 109.9;eosinophil: 56.0;neutrophil: 110.4;NK-cell: 86.6" "Group enriched" "Detected in many" 4 "granulocytes: 110.4;NK-cells: 86.6" "Cancer enhanced" "Detected in many" "Kidney cancer: 38.9" "Adipose subcutaneous - Smooth muscle cells, Colon - Smooth muscle cells, Prostate - Smooth muscle cells" "Region enhanced" "Detected in all" "white matter: 842.8" "Low region specificity" "Detected in all" "HPA015640, HPA073306" Uncertain Enhanced Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 49: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 32: Smooth muscle cells - Muscle contraction" 34 Nucleoplasm "HPA015640: AB_1858405, HPA073306: " "unprognostic (4.56e-2)" "unprognostic (6.86e-2)" "unprognostic (2.60e-1)" "prognostic unfavorable (8.89e-4)" "unprognostic (1.57e-3)" "unprognostic (1.64e-1)" "unprognostic (9.73e-6)" "unprognostic (6.06e-3)" "unprognostic (3.07e-2)" "unprognostic (4.74e-2)" "unprognostic (7.66e-2)" "unprognostic (1.80e-1)" "prognostic unfavorable (8.48e-7)" "unprognostic (5.40e-2)" "unprognostic (1.59e-1)" "unprognostic (1.48e-3)" "unprognostic (7.80e-3)" TUNAR "BNLN, HI-LNC78, LINC00617, TUNA" ENSG00000250366 "TCL1 upstream neural differentiation-associated RNA" A0A1B0GTB2 14 95866587-95925663 "Predicted membrane proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 12.6;endometrium 1: 6.3;fallopian tube: 8.2;retina: 8.3" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 9.0;Glandular and luminal cells: 16.4;Horizontal cells: 15.1;Oocytes: 11.8;Pancreatic endocrine cells: 5.1;Secretory cells: 4.6" "Cancer enhanced" "Detected in many" "testis cancer: 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Spermatogonia, Thyroid - Parafollicular cells" "Low region specificity" "Detected in all" NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 49: Hindbrain - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 37: Glandular & Luminal cells - Unknown function" "unprognostic (1.28e-3)" "unprognostic (3.94e-1)" "unprognostic (4.10e-2)" "unprognostic (1.69e-1)" "unprognostic (1.41e-2)" "unprognostic (1.34e-1)" "prognostic favorable (1.55e-4)" "unprognostic (5.33e-2)" "unprognostic (2.92e-2)" "unprognostic (1.18e-1)" TXK "BTKL, PSCTK5, PTK4, RLK, TKL" ENSG00000074966 "TXK tyrosine kinase" P42681 4 48066393-48134250 "Enzymes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Transcription, Transcription regulation" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 8.2;lymphoid tissue: 15.0" "Group enriched" "Detected in many" 6 "NK-cells: 221.1;T-cells: 62.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "NK-cell: 118.7" "Group enriched" "Detected in many" 18 "NK-cells: 118.7;T-cells: 49.8" "Low cancer specificity" "Detected in some" "Adipose visceral - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung)" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA078636 Supported "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 19: NK-cells - Adaptive immune response" 16 "Nucleoplasm, Cytosol" "Nucleoli, Plasma membrane" "HPA078636: " "unprognostic (1.04e-2)" "unprognostic (2.21e-2)" "unprognostic (4.13e-2)" "unprognostic (9.24e-3)" "unprognostic (1.09e-2)" "unprognostic (2.58e-4)" "unprognostic (1.32e-1)" "unprognostic (1.94e-1)" "unprognostic (1.50e-1)" "unprognostic (6.39e-3)" "unprognostic (8.13e-2)" "unprognostic (4.06e-1)" "unprognostic (1.33e-1)" "unprognostic (1.37e-1)" "unprognostic (1.61e-1)" "unprognostic (2.59e-1)" "unprognostic (2.04e-2)" UBASH3B "KIAA1959, STS-1, TULA-2, TULA2" ENSG00000154127 "Ubiquitin associated and SH3 domain containing B" Q8TF42 11 122655722-122814473 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.6;lymphoid tissue: 15.2;placenta: 13.3" "Cell type enhanced" "Detected in many" "dendritic cells: 119.3;Extravillous trophoblasts: 60.4;Inhibitory neurons: 158.8;Langerhans cells: 61.3;monocytes: 106.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038605, HPA038606, HPA038607" Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 23000 "Cluster 25: Non-specific - Unknown function" "Cluster 16: Non-specific - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 65: Neurons - Synaptic function" 25 Cytosol "Nucleoplasm, Nuclear bodies" "HPA038605: AB_10669648, HPA038606: , HPA038607: AB_2676112" "unprognostic (4.94e-2)" "unprognostic (6.03e-3)" "unprognostic (1.34e-1)" "unprognostic (2.98e-1)" "unprognostic (2.02e-1)" "unprognostic (1.49e-1)" "unprognostic (9.09e-2)" "unprognostic (4.67e-3)" "unprognostic (1.21e-1)" "unprognostic (1.95e-1)" "unprognostic (1.46e-3)" "unprognostic (6.20e-2)" "unprognostic (9.02e-3)" "unprognostic (1.54e-1)" "unprognostic (3.22e-2)" "unprognostic (2.72e-3)" "unprognostic (1.53e-1)" UGT3A2 ENSG00000168671 "UDP glycosyltransferase family 3 member A2" Q3SY77 5 36035021-36071358 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.4;lymphoid tissue: 14.3;skin 1: 10.0" "Cell type enhanced" "Detected in some" "Collecting duct cells: 1.9;Early spermatids: 4.2;Late spermatids: 8.6;Proximal tubular cells: 2.0" "Cancer enriched" "Detected in some" 5 "testis cancer: 4.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Bone cancer: 178.0" "Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells" "Not detected" "Not detected" HPA059475 Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" Yes NA "Cluster 13: Skin - Cornification" "Cluster 49: Hindbrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 36: Late spermatids - Unknown function" Nucleoplasm "Golgi apparatus, Cytosol" "HPA059475: AB_2684031" "unprognostic (1.83e-4)" "unprognostic (9.94e-2)" "unprognostic (8.87e-2)" "unprognostic (4.82e-4)" "unprognostic (3.18e-1)" "unprognostic (3.52e-2)" "unprognostic (1.56e-1)" "unprognostic (6.08e-2)" "unprognostic (2.04e-1)" "unprognostic (8.13e-2)" "unprognostic (7.49e-2)" "unprognostic (4.17e-2)" "unprognostic (1.36e-3)" "unprognostic (6.65e-2)" "unprognostic (7.52e-2)" "unprognostic (7.38e-2)" "unprognostic (4.52e-3)" USB1 "C16orf57, FLJ13154, HVSL1, Mpn1" ENSG00000103005 "U6 snRNA biogenesis phosphodiesterase 1" Q9BQ65 16 57999546-58021618 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Hydrolase, Lyase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041791, HPA059854" Approved Supported Nucleoplasm NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 49: Hindbrain - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 45: Non-specific - Mixed function" Nucleoplasm "HPA041791: AB_10793933, HPA059854: AB_2684143" "unprognostic (2.79e-1)" "unprognostic (3.84e-2)" "unprognostic (1.21e-2)" "unprognostic (9.65e-2)" "unprognostic (2.03e-1)" "unprognostic (2.23e-3)" "prognostic unfavorable (6.69e-7)" "unprognostic (4.30e-3)" "unprognostic (2.92e-1)" "unprognostic (4.98e-2)" "unprognostic (1.95e-1)" "unprognostic (1.78e-2)" "prognostic unfavorable (2.02e-4)" "unprognostic (2.18e-1)" "unprognostic (1.56e-1)" "unprognostic (1.06e-3)" "unprognostic (5.04e-2)" USP14 "TGT, Ubp6" ENSG00000101557 "Ubiquitin specific peptidase 14" P54578 18 158383-214629 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001308 Approved Supported "Plasma membrane,Cytosol" NA NA 2700000 "Cluster 33: Non-specific - ATP binding" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 39: Non-specific - Basic cellular processes" 3 "Plasma membrane, Cytosol" "HPA001308: AB_1080499" "unprognostic (2.21e-1)" "unprognostic (4.05e-2)" "unprognostic (1.90e-1)" "unprognostic (2.59e-3)" "unprognostic (6.04e-2)" "prognostic unfavorable (7.81e-5)" "prognostic unfavorable (4.30e-5)" "unprognostic (5.14e-2)" "unprognostic (5.00e-2)" "prognostic favorable (7.91e-4)" "unprognostic (1.64e-2)" "unprognostic (2.39e-1)" "unprognostic (1.51e-3)" "unprognostic (2.58e-1)" "unprognostic (1.55e-1)" "unprognostic (2.20e-2)" "unprognostic (3.76e-2)" UTRN "DMDL, DRP, DRP1" ENSG00000152818 Utrophin P46939 6 144285335-144853034 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 542.8;Late spermatids: 385.0;Lymphatic endothelial cells: 440.1;Microglial cells: 406.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 157.0" "Lineage enriched" "Detected in all" 4 "monocytes: 157.0" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Lung - Alveolar cells type 1, Skeletal muscle - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016348, HPA018894" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 4200 "Cluster 40: Monocytes - Innate immune response" "Cluster 16: Non-specific - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 55: Non-specific - Transcription" 2 "Nucleoplasm, Plasma membrane" "CAB016348: AB_628424, HPA018894: AB_10600839" "unprognostic (3.47e-2)" "unprognostic (2.82e-1)" "unprognostic (2.32e-1)" "unprognostic (6.87e-3)" "unprognostic (1.75e-1)" "unprognostic (3.30e-2)" "unprognostic (3.99e-3)" "unprognostic (2.44e-1)" "unprognostic (9.24e-2)" "unprognostic (1.29e-1)" "unprognostic (2.72e-1)" "unprognostic (7.10e-2)" "prognostic favorable (7.61e-5)" "unprognostic (6.32e-2)" "unprognostic (2.20e-1)" "unprognostic (1.66e-1)" "unprognostic (1.49e-2)" VAPA "hVAP-33, VAP-A" ENSG00000101558 "VAMP associated protein A" Q9P0L0 18 9914016-9960021 "Plasma proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009174 Approved Enhanced "Endoplasmic reticulum" NA NA 580000 "Cluster 29: Non-specific - Unknown function" "Cluster 56: Non-specific - Unknown function" "Cluster 49: Hindbrain - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 15: Non-specific - Mixed function" 37 "Endoplasmic reticulum" "HPA009174: AB_1080549" "unprognostic (4.03e-2)" "unprognostic (7.47e-2)" "unprognostic (9.36e-2)" "unprognostic (5.20e-2)" "unprognostic (2.00e-1)" "unprognostic (2.99e-2)" "unprognostic (4.79e-3)" "unprognostic (1.80e-1)" "unprognostic (5.39e-2)" "unprognostic (6.80e-3)" "unprognostic (2.99e-2)" "unprognostic (8.11e-2)" "prognostic favorable (5.72e-7)" "unprognostic (1.03e-1)" "unprognostic (1.66e-1)" "unprognostic (1.23e-1)" "unprognostic (5.77e-2)" VGLL2 ENSG00000170162 "Vestigial like family member 2" Q8N8G2 6 117265558-117273565 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "skeletal muscle: 124.9" "Cell type enriched" "Detected in some" 12 "Skeletal myocytes: 32.2" "Cancer enhanced" "Detected in single" "glioma: 0.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "ovarian cancer: 19.3;Sarcoma: 10.2" "Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 49: Hindbrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 2: Skeletal myocytes - Muscle contraction" 1 "unprognostic (3.02e-2)" "unprognostic (3.09e-2)" "unprognostic (1.75e-1)" "unprognostic (4.92e-1)" WDFY1 "FENS-1, KIAA1435, WDF1, ZFYVE17" ENSG00000085449 "WD repeat and FYVE domain containing 1" Q8IWB7 2 223855716-223945357 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050603, HPA079597" Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 49: Hindbrain - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 55: Non-specific - Transcription" "Golgi apparatus, Vesicles" "HPA050603: AB_2681188, HPA079597: " "unprognostic (2.49e-1)" "unprognostic (1.24e-1)" "unprognostic (2.94e-1)" "unprognostic (7.62e-2)" "unprognostic (8.24e-2)" "unprognostic (5.31e-2)" "unprognostic (2.63e-2)" "unprognostic (7.10e-2)" "unprognostic (1.26e-1)" "unprognostic (2.29e-2)" "unprognostic (1.23e-3)" "unprognostic (1.36e-1)" "unprognostic (3.81e-3)" "unprognostic (3.94e-1)" "unprognostic (2.98e-1)" "unprognostic (3.04e-1)" "unprognostic (7.55e-2)" WDR11 "BRWD2, DR11, FLJ10506, HH14, KIAA1351, SRI1, WDR15" ENSG00000120008 "WD repeat domain 11" Q9BZH6 10 120851305-120909524 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038980 Approved Approved Microtubules,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 51: Thyroid gland - Unknown function" "Cluster 49: Hindbrain - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 73: B-cells - B-cell function" 1 "Microtubules, Cytosol" "HPA038980: AB_10675955" "unprognostic (8.98e-2)" "unprognostic (8.83e-3)" "unprognostic (1.27e-1)" "unprognostic (5.07e-2)" "unprognostic (2.99e-2)" "unprognostic (2.57e-3)" "unprognostic (1.45e-1)" "unprognostic (2.98e-3)" "unprognostic (2.84e-1)" "unprognostic (3.84e-1)" "unprognostic (8.31e-2)" "unprognostic (1.80e-3)" "prognostic favorable (5.04e-4)" "unprognostic (5.09e-2)" "unprognostic (1.87e-1)" "unprognostic (8.99e-2)" "unprognostic (2.38e-2)" ZC4H2 "HCA127, KIAA1166, MCS, MRXS4, WWS" ENSG00000126970 "Zinc finger C4H2-type containing" Q9NQZ6 X 64915802-65034713 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation "Developmental protein" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 36.1;Inhibitory neurons: 37.8;Oligodendrocyte precursor cells: 54.7;Oligodendrocytes: 54.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049584 Approved Approved Vesicles,Microtubules NA NA "Cluster 24: Non-specific - Transcription" "Cluster 64: Neuronal - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 69: Neurons - Neuronal signaling" 14 "Vesicles, Microtubules" "HPA049584: AB_2680825" "unprognostic (9.55e-3)" "unprognostic (1.03e-1)" "unprognostic (4.40e-1)" "unprognostic (1.56e-1)" "unprognostic (7.29e-3)" "unprognostic (9.71e-2)" "unprognostic (1.64e-3)" "unprognostic (9.72e-2)" "unprognostic (2.98e-1)" "unprognostic (3.34e-1)" "unprognostic (2.31e-2)" "unprognostic (6.44e-2)" "unprognostic (1.84e-3)" "unprognostic (2.06e-1)" "unprognostic (1.58e-1)" "prognostic unfavorable (3.51e-5)" "unprognostic (5.34e-2)" ZNF442 FLJ14356 ENSG00000198342 "Zinc finger protein 442" Q9H7R0 19 12345944-12365905 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 7.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "HPA045738, HPA053407" Uncertain Approved "Nuclear membrane,Vesicles" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 16: Non-specific - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 80: Non-specific - Transcription" "Nuclear membrane" Vesicles "HPA045738: AB_10968057, HPA053407: AB_2682138" "unprognostic (2.61e-2)" "unprognostic (3.32e-2)" "unprognostic (1.59e-1)" "unprognostic (7.36e-2)" "unprognostic (1.28e-1)" "unprognostic (5.53e-2)" "unprognostic (6.64e-2)" "unprognostic (2.07e-2)" "unprognostic (3.17e-3)" "unprognostic (1.35e-1)" "unprognostic (7.52e-3)" "unprognostic (1.78e-1)" "unprognostic (1.91e-3)" "unprognostic (1.38e-1)" "unprognostic (1.30e-1)" "unprognostic (5.80e-2)" "unprognostic (1.99e-2)" ZNF648 FLJ46813 ENSG00000179930 "Zinc finger protein 648" Q5T619 1 182054570-182061712 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Ionocytes: 1.5;Oocytes: 2.2;Spermatogonia: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA053897 Uncertain NA NA "Cluster 49: Hindbrain - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 35: Respiratory epithelial cells - Unknown function" 50 "HPA053897: AB_2682297" "unprognostic (3.52e-4)" "unprognostic (1.44e-1)" "unprognostic (7.96e-2)" "unprognostic (1.69e-3)" "unprognostic (2.30e-1)" "unprognostic (4.33e-2)" "unprognostic (1.09e-1)" "unprognostic (1.19e-2)" "unprognostic (2.95e-2)" "unprognostic (2.24e-1)" "unprognostic (1.38e-2)" "unprognostic (8.16e-6)" "unprognostic (4.96e-2)" "unprognostic (3.25e-1)" "unprognostic (2.42e-1)" "unprognostic (2.83e-1)" ZNF730 ENSG00000183850 "Zinc finger protein 730" Q6ZMV8 19 23075210-23147221 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 4.9" "Cell type enhanced" "Detected in some" "Astrocytes: 8.7;Early spermatids: 32.5;Late spermatids: 23.9;Oligodendrocyte precursor cells: 11.3" "Cancer enhanced" "Detected in some" "testis cancer: 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" NA NA "Cluster 16: Non-specific - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 13: Spermatids - Transcription" "unprognostic (6.75e-3)" "unprognostic (2.49e-2)" "unprognostic (3.64e-1)" "unprognostic (1.60e-3)" "unprognostic (3.33e-2)" "unprognostic (1.78e-2)" "unprognostic (4.24e-4)" "unprognostic (9.34e-2)" "unprognostic (1.01e-1)" "unprognostic (4.92e-2)" "unprognostic (3.10e-2)" "unprognostic (5.98e-2)" "unprognostic (1.37e-3)" "unprognostic (5.53e-2)" "unprognostic (1.90e-1)" "unprognostic (6.67e-2)" "unprognostic (1.43e-2)" ZNF75D "D8C6, ZKSCAN24, ZNF75, ZNF82, ZSCAN28" ENSG00000186376 "Zinc finger protein 75D" P51815 X 135248920-135344109 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 9 "Early spermatids: 158.8;Late spermatids: 325.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004705 Supported Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 47: Spleen - Immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 63: Late spermatids - Spermatogenesis" "Nucleoplasm, Golgi apparatus" "HPA004705: AB_1080749" "unprognostic (1.56e-3)" "unprognostic (7.96e-3)" "unprognostic (3.07e-1)" "unprognostic (5.12e-2)" "unprognostic (1.30e-1)" "unprognostic (3.00e-2)" "unprognostic (7.92e-2)" "unprognostic (1.32e-3)" "unprognostic (9.17e-2)" "unprognostic (1.81e-1)" "unprognostic (1.15e-2)" "unprognostic (2.13e-2)" "prognostic favorable (1.31e-4)" "unprognostic (1.09e-2)" "unprognostic (1.96e-1)" "unprognostic (1.15e-1)" "prognostic favorable (7.42e-5)" ZPLD1 ENSG00000170044 "Zona pellucida like domain containing 1" Q8TCW7 3 102099244-102479841 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 2.2;retina: 2.4" "Cell type enhanced" "Detected in some" "Cholangiocytes: 5.7;Ductal cells: 3.7;Early spermatids: 2.7;Late spermatids: 6.1;Muller glia cells: 14.6;Pancreatic endocrine cells: 6.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "Rhabdoid: 39.2" "Colon - Colon enteroendocrine cells" "Region enriched" "Detected in single" 7 "olfactory bulb: 2.8" "Not detected" "Not detected" HPA077519 Approved Nucleoplasm "Intracellular and membrane" "No annotated function" NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 49: Hindbrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 10: Muller glia cells - Visual perception" Nucleoplasm "HPA077519: AB_2732349" "unprognostic (2.49e-1)" "unprognostic (2.83e-3)" "unprognostic (6.38e-3)" "unprognostic (1.88e-1)" "unprognostic (5.02e-2)" "unprognostic (1.37e-2)" "unprognostic (2.68e-1)" "unprognostic (2.63e-1)" "unprognostic (4.63e-1)" "unprognostic (2.89e-4)" "unprognostic (4.59e-2)" "unprognostic (1.05e-3)" "unprognostic (1.97e-2)" "unprognostic (9.65e-2)" "unprognostic (1.41e-1)" "unprognostic (1.23e-2)"