Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "Secretome function" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Brain expression cluster" "Cell line expression cluster" "Single cell expression cluster" Interactions "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" ACTBL2 DKFZp686D0972 ENSG00000169067 "Actin beta like 2" Q562R1 5 57480018-57482811 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Ductal cells: 1.2;Early spermatids: 1.6;Late spermatids: 1.5;Mesothelial cells: 1.1;Mucus glandular cells: 1.7;Pancreatic endocrine cells: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 5.0" "Skin - Inner root sheath cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041264, HPA041271" Uncertain NA NA 830000000 "Cluster 61: BICR 18 - Protein kinases" "Cluster 45: Non-specific - Mixed function" 1 "HPA041264: AB_2677383, HPA041271: AB_2677386" "unprognostic (7.83e-2)" "unprognostic (1.70e-1)" "unprognostic (2.96e-1)" "unprognostic (8.66e-2)" "unprognostic (2.57e-2)" "unprognostic (2.39e-1)" "unprognostic (3.63e-2)" "unprognostic (1.22e-1)" "unprognostic (1.14e-3)" "unprognostic (3.20e-1)" "unprognostic (2.48e-3)" "unprognostic (1.60e-2)" "unprognostic (2.04e-2)" "unprognostic (1.92e-2)" ACTG1 "ACTG, DFNA20, DFNA26" ENSG00000184009 "Actin gamma 1" P63261 17 81509413-81523847 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Deafness, Disease variant, Intellectual disability, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041264, HPA041271" Approved NA NA 4900000000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 27: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 45: Non-specific - Mixed function" 14 "HPA041264: AB_2677383, HPA041271: AB_2677386" "unprognostic (3.95e-2)" "unprognostic (3.38e-1)" "prognostic favorable (2.41e-4)" "unprognostic (2.73e-2)" "unprognostic (1.16e-2)" "unprognostic (1.03e-1)" "unprognostic (1.29e-3)" "unprognostic (2.45e-3)" "unprognostic (3.47e-2)" "unprognostic (3.06e-2)" "unprognostic (4.54e-2)" "unprognostic (9.03e-2)" "unprognostic (1.51e-2)" "unprognostic (1.13e-1)" "unprognostic (2.43e-2)" "unprognostic (1.25e-1)" "unprognostic (3.40e-3)" ACTR1A "ARP1, Arp1A" ENSG00000138107 "Actin related protein 1A" P61163 10 102461881-102502712 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Endothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037193, HPA047443" Approved Approved Microtubules NA NA 560000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 45: Non-specific - Mixed function" 2 Microtubules "CAB037193: AB_258253, HPA047443: AB_2680049" "unprognostic (9.64e-3)" "unprognostic (1.92e-2)" "unprognostic (8.34e-2)" "unprognostic (4.05e-2)" "unprognostic (2.57e-1)" "unprognostic (3.48e-1)" "unprognostic (2.20e-3)" "unprognostic (2.41e-1)" "unprognostic (1.86e-2)" "unprognostic (1.01e-1)" "unprognostic (1.66e-2)" "unprognostic (7.77e-2)" "unprognostic (3.41e-2)" "unprognostic (1.04e-1)" "unprognostic (1.40e-1)" "unprognostic (3.10e-1)" "unprognostic (4.13e-1)" ADAM9 "CORD9, KIAA0021, MCMP, MDC9, Mltng" ENSG00000168615 "ADAM metallopeptidase domain 9" Q13443 8 38996754-39105445 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Cone-rod dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Mucus glandular cells: 172.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 4.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004000 Approved "Endoplasmic reticulum,Vesicles" "Secreted - unknown location" Enzyme NA NA 740000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 62: Connective tissue - ECM organization" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" 4 Vesicles "Endoplasmic reticulum" "HPA004000: AB_1844584" "prognostic unfavorable (1.14e-4)" "prognostic unfavorable (2.25e-4)" "unprognostic (1.32e-3)" "unprognostic (1.27e-1)" "unprognostic (2.86e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (7.21e-6)" "unprognostic (5.77e-2)" "unprognostic (1.55e-1)" "unprognostic (1.48e-2)" "prognostic unfavorable (2.52e-5)" "unprognostic (5.83e-2)" "prognostic unfavorable (3.99e-4)" "unprognostic (2.80e-1)" "unprognostic (5.76e-2)" "unprognostic (2.27e-1)" "unprognostic (1.23e-2)" ADGRF4 "FLJ38076, GPR115, PGR18" ENSG00000153294 "Adhesion G protein-coupled receptor F4" Q8IZF3 6 47685864-47722021 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 17.8;skin 1: 37.7" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 7.6;Distal enterocytes: 8.3;Extravillous trophoblasts: 17.3;Squamous epithelial cells: 16.5;Suprabasal keratinocytes: 32.1;Syncytiotrophoblasts: 9.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 8.2" "Region enriched" "Detected in single" 5 "hypothalamus: 4.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 16.7" "Prostate - Urothelial cells" "Low region specificity" "Detected in some" "Region enhanced" "Detected in single" "spinal cord: 2.0" "HPA007131, HPA007158" Enhanced Uncertain Mitochondria NA NA "Cluster 13: Skin - Cornification" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" Mitochondria "HPA007131: AB_2667756, HPA007158: AB_1849254" "unprognostic (1.40e-2)" "unprognostic (7.06e-3)" "unprognostic (2.11e-1)" "unprognostic (4.68e-2)" "unprognostic (3.79e-2)" "unprognostic (3.77e-2)" "unprognostic (2.04e-3)" "unprognostic (2.64e-1)" "unprognostic (3.47e-1)" "prognostic unfavorable (5.52e-4)" "unprognostic (2.86e-1)" "unprognostic (1.66e-8)" "unprognostic (1.62e-3)" "unprognostic (2.01e-1)" "unprognostic (1.46e-1)" "unprognostic (2.25e-1)" AGRN AGRIN ENSG00000188157 Agrin O00468 1 1020120-1056118 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" Differentiation "Developmental protein" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 63.7;Collecting duct cells: 89.5;Ductal cells: 62.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040090 Approved Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" "Developmental protein" NA NA 20000000 "Cluster 34: Non-specific - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" 1 Cytosol "Plasma membrane" "HPA040090: AB_10805603" "unprognostic (8.04e-2)" "unprognostic (8.25e-3)" "unprognostic (1.42e-3)" "unprognostic (1.23e-1)" "unprognostic (3.26e-2)" "unprognostic (2.41e-2)" "prognostic unfavorable (4.62e-4)" "unprognostic (2.82e-3)" "unprognostic (1.32e-1)" "unprognostic (3.33e-2)" "unprognostic (9.49e-3)" "unprognostic (1.06e-1)" "unprognostic (8.46e-2)" "unprognostic (8.49e-2)" "unprognostic (2.07e-2)" "unprognostic (4.08e-1)" "unprognostic (1.31e-2)" AJUBA "JUB, MGC15563" ENSG00000129474 "Ajuba LIM protein" Q96IF1 14 22971177-22982551 "Cancer-related genes, Predicted intracellular proteins" "Cell adhesion, Cell cycle, RNA-mediated gene silencing, Transcription, Transcription regulation" Repressor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 60.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 43.2;Basal keratinocytes: 32.0;Basal respiratory cells: 25.7;Suprabasal keratinocytes: 30.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA006171 Approved Approved "Nucleoplasm,Golgi apparatus" NA Yes "Cluster 13: Skin - Cornification" "Cluster 3: Choroid plexus - Cilium" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 12 "Nucleoplasm, Golgi apparatus" "HPA006171: AB_1852044" "unprognostic (1.15e-1)" "unprognostic (2.99e-2)" "unprognostic (2.39e-1)" "unprognostic (1.24e-3)" "unprognostic (9.81e-2)" "unprognostic (1.49e-1)" "unprognostic (1.80e-3)" "unprognostic (2.73e-1)" "unprognostic (1.39e-1)" "unprognostic (1.86e-1)" "prognostic unfavorable (5.67e-4)" "unprognostic (1.47e-1)" "unprognostic (3.19e-3)" "unprognostic (2.94e-1)" "unprognostic (2.68e-1)" "unprognostic (9.35e-3)" "unprognostic (2.07e-1)" ALOXE3 "E-LOX, eLOX3" ENSG00000179148 "Arachidonate lipoxygenase 3" Q9BYJ1 17 8095900-8119047 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Dioxygenase, Isomerase, Lyase, Oxidoreductase" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 22 "skin 1: 54.5" "Cell type enriched" "Detected in some" 7 "Oocytes: 40.4" "Group enriched" "Detected in some" 4 "cervical cancer: 1.1;head and neck cancer: 3.9;melanoma: 1.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA023120, HPA078597" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 13: Skin - Cornification" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 3 "Plasma membrane, Cytosol" "HPA023120: AB_10959300, HPA078597: AB_2732385" "unprognostic (2.40e-1)" "unprognostic (3.01e-2)" "unprognostic (1.87e-3)" "unprognostic (2.09e-4)" "unprognostic (1.07e-2)" "unprognostic (4.06e-2)" "unprognostic (3.56e-4)" "unprognostic (3.60e-1)" "unprognostic (4.65e-2)" "unprognostic (3.82e-2)" "unprognostic (3.72e-1)" "unprognostic (3.66e-5)" "unprognostic (9.81e-2)" "unprognostic (2.55e-1)" "unprognostic (1.08e-2)" "unprognostic (2.88e-2)" ANKRD36C DKFZp667P0924 ENSG00000174501 "Ankyrin repeat domain 36C" Q5JPF3 2 95836919-95991831 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.6" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 1117.6;Gastric mucus-secreting cells: 479.9;Mucus glandular cells: 1064.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA051757, HPA057661" Approved Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 40: Non-specific - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 45: Non-specific - Mixed function" "Nucleoplasm, Cytosol" "HPA051757: AB_2681594, HPA057661: AB_2683494" "unprognostic (2.21e-1)" "unprognostic (5.39e-2)" "unprognostic (6.32e-2)" "unprognostic (2.50e-1)" "unprognostic (1.83e-1)" "unprognostic (3.79e-3)" "unprognostic (1.29e-1)" "unprognostic (5.57e-2)" "unprognostic (1.57e-1)" "unprognostic (2.03e-1)" "unprognostic (1.44e-2)" "unprognostic (5.29e-3)" "unprognostic (5.35e-6)" "unprognostic (9.99e-2)" "unprognostic (2.47e-1)" "unprognostic (3.44e-2)" "unprognostic (1.79e-1)" ANXA10 ANX14 ENSG00000109511 "Annexin A10" Q9UJ72 4 168092537-168187736 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "stomach 1: 473.8" "Cell type enriched" "Detected in some" 6 "Gastric mucus-secreting cells: 597.2" "Group enriched" "Detected in many" 5 "pancreatic cancer: 62.4;stomach cancer: 42.2;urothelial cancer: 19.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 72.6;Gastric cancer: 50.4;pancreatic cancer: 55.5" "Liver - Hepatocytes, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005469, HPA074650" Enhanced Approved Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 66: Non-specific - Mitochondria" "Cluster 45: Non-specific - Mixed function" 2 "Nucleoplasm, Nucleoli" Vesicles "HPA005469: AB_1844849, HPA074650: " "unprognostic (2.29e-2)" "unprognostic (8.71e-3)" "unprognostic (2.48e-2)" "unprognostic (1.71e-1)" "unprognostic (4.69e-1)" "unprognostic (2.29e-2)" "prognostic favorable (3.64e-6)" "unprognostic (1.18e-3)" "unprognostic (2.88e-1)" "unprognostic (8.61e-4)" "unprognostic (3.43e-2)" "unprognostic (1.84e-1)" "unprognostic (1.69e-3)" "unprognostic (8.41e-2)" "unprognostic (4.01e-1)" "unprognostic (2.04e-1)" "unprognostic (8.89e-3)" ANXA11 ANX11 ENSG00000122359 "Annexin A11" P50995 10 80150889-80205572 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 445.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004851, HPA027545" Supported Supported Nucleoplasm,Cytosol NA NA 210000 "Cluster 21: Neutrophils - Unknown function" "Cluster 35: Non-specific - Mitochondria" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 8 Nucleoplasm Cytosol "CAB004851: AB_626682, HPA027545: AB_1844851" "unprognostic (1.85e-2)" "unprognostic (2.85e-2)" "unprognostic (5.35e-3)" "unprognostic (5.06e-2)" "unprognostic (8.18e-3)" "unprognostic (1.99e-1)" "unprognostic (4.01e-3)" "unprognostic (6.28e-2)" "unprognostic (2.32e-2)" "unprognostic (4.88e-2)" "unprognostic (3.46e-2)" "unprognostic (2.56e-2)" "prognostic favorable (6.69e-8)" "unprognostic (2.69e-3)" "unprognostic (1.84e-1)" "unprognostic (6.79e-2)" "unprognostic (2.02e-1)" ANXA2 "ANX2, ANX2L4, CAL1H, LIP2, LPC2D" ENSG00000182718 "Annexin A2" P07355 15 60347134-60402883 "Cancer-related genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Host-virus interaction" RNA-binding "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 2124.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 5295.0;Ductal cells: 3448.7;Pancreatic endocrine cells: 3363.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 4446.3;classical monocyte: 2767.4;intermediate monocyte: 2404.9;myeloid DC: 4023.2;non-classical monocyte: 2699.3;T-reg: 1686.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Ductal cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 213.0" "CAB004311, HPA046964, HPA061798" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to blood" Other NA NA 19000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 12: Non-specific - Vasculature" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Non-specific - Mixed function" 9 "Plasma membrane" Cytosol "CAB004311: AB_626677, HPA046964: AB_2732537, HPA061798: AB_2732671" "unprognostic (1.61e-1)" "unprognostic (1.31e-3)" "unprognostic (1.84e-1)" "prognostic favorable (6.88e-5)" "unprognostic (4.06e-3)" "unprognostic (5.42e-3)" "prognostic unfavorable (2.54e-5)" "prognostic unfavorable (7.51e-4)" "unprognostic (2.94e-1)" "unprognostic (4.10e-3)" "prognostic unfavorable (8.47e-6)" "unprognostic (5.16e-2)" "prognostic unfavorable (2.11e-6)" "unprognostic (7.74e-2)" "unprognostic (2.55e-1)" "unprognostic (7.41e-2)" "prognostic unfavorable (6.59e-5)" ANXA3 ANX3 ENSG00000138772 "Annexin A3" P12429 4 78551747-78610451 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Phospholipase A2 inhibitor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 334.1" "Cell type enhanced" "Detected in many" "Adipocytes: 273.2;Alveolar cells type 1: 599.3;Ductal cells: 343.6;Pancreatic endocrine cells: 353.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 328 "neutrophil: 208.7" "Lineage enriched" "Detected in single" 328 "granulocytes: 208.7" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 1, Pancreas - Ductal cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "HPA013398, HPA013431" Enhanced Supported "Plasma membrane" NA NA 6400000 "Cluster 4: Neutrophils - Degranulation" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" "Plasma membrane" "HPA013398: AB_1844861, HPA013431: AB_1844862" "unprognostic (2.66e-1)" "unprognostic (5.65e-3)" "unprognostic (4.92e-3)" "unprognostic (8.67e-2)" "unprognostic (2.41e-1)" "unprognostic (5.02e-3)" "unprognostic (4.17e-2)" "unprognostic (1.87e-1)" "unprognostic (5.09e-2)" "unprognostic (2.10e-3)" "prognostic unfavorable (1.28e-4)" "unprognostic (4.82e-2)" "prognostic favorable (8.48e-6)" "unprognostic (2.23e-1)" "unprognostic (2.02e-2)" "unprognostic (7.20e-2)" "unprognostic (3.30e-2)" AP1S3 sigma1C ENSG00000152056 "Adaptor related protein complex 1 subunit sigma 3" Q96PC3 2 223667680-223838027 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 47.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 43.0;Cone photoreceptor cells: 44.2;Cytotrophoblasts: 48.0;granulocytes: 44.4;Langerhans cells: 35.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 4.6;dendritic cells: 3.8;granulocytes: 5.6" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA066782 Approved Supported Vesicles NA NA "Cluster 32: Basophils - Transcription" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 2 Vesicles "HPA066782: AB_2685720" "unprognostic (9.45e-3)" "unprognostic (1.79e-1)" "unprognostic (7.52e-2)" "unprognostic (5.80e-2)" "unprognostic (4.37e-2)" "unprognostic (4.89e-1)" "unprognostic (1.65e-3)" "prognostic unfavorable (3.36e-5)" "unprognostic (1.81e-1)" "unprognostic (1.47e-1)" "prognostic unfavorable (2.08e-5)" "unprognostic (1.56e-1)" "unprognostic (2.33e-1)" "unprognostic (2.50e-2)" "unprognostic (1.90e-1)" "unprognostic (2.32e-2)" "unprognostic (4.61e-2)" APH1A "APH-1A, CGI-78" ENSG00000117362 "Aph-1 homolog A, gamma-secretase subunit" Q96BI3 1 150265399-150269580 "Predicted membrane proteins, Transporters" "Notch signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB037272 Approved NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 13: Skin - Cornification" "Cluster 19: Astrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 45: Non-specific - Mixed function" 21 "CAB037272: AB_476776" "unprognostic (1.00e-1)" "unprognostic (5.55e-2)" "unprognostic (8.84e-2)" "unprognostic (1.20e-3)" "unprognostic (4.92e-2)" "unprognostic (3.55e-2)" "unprognostic (2.75e-3)" "unprognostic (4.42e-2)" "unprognostic (1.20e-1)" "unprognostic (1.68e-2)" "unprognostic (2.42e-3)" "unprognostic (1.53e-1)" "unprognostic (6.99e-2)" "unprognostic (4.48e-2)" "unprognostic (1.66e-1)" "unprognostic (2.53e-1)" "unprognostic (1.87e-1)" APLN "apelin, XNPEP2" ENSG00000171388 Apelin Q9ULZ1 X 129645259-129654956 "Predicted secreted proteins" "Angiogenesis, Gastrulation, Host-virus interaction" "Developmental protein, Hormone" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.3;placenta: 52.2" "Cell type enhanced" "Detected in some" "Astrocytes: 7.7;Breast myoepithelial cells: 8.1;Cardiomyocytes: 14.0;Endothelial cells: 20.9;Mesothelial cells: 4.0" "Group enriched" "Detected in all" 6 "glioma: 44.2;renal cancer: 21.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Kidney cancer: 18.8;prostate cancer: 64.5" "Kidney - Podocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in other tissues" Hormone NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 45: Non-specific - Mixed function" 1 "unprognostic (1.50e-1)" "prognostic unfavorable (2.92e-4)" "unprognostic (1.57e-1)" "unprognostic (1.27e-1)" "unprognostic (4.50e-2)" "unprognostic (5.94e-2)" "prognostic unfavorable (9.32e-4)" "prognostic unfavorable (6.09e-4)" "unprognostic (4.71e-2)" "unprognostic (2.25e-1)" "unprognostic (3.30e-1)" "unprognostic (9.12e-2)" "prognostic unfavorable (9.61e-5)" "unprognostic (1.55e-1)" "unprognostic (1.15e-1)" "unprognostic (2.26e-1)" "unprognostic (8.42e-2)" ARHGAP8 "BPGAP1, FLJ20185" ENSG00000241484 "Rho GTPase activating protein 8" P85298 22 44752558-44862788 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 27.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 26.5;Ductal cells: 24.8;Exocrine glandular cells: 20.2;Oocytes: 55.9;Undifferentiated cells: 19.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Lung - Alveolar cells type 2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA069694 Approved NA No "Cluster 52: Kidney - Transmembrane transport" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" "HPA069694: AB_2686173" "unprognostic (4.14e-1)" "unprognostic (1.21e-2)" "unprognostic (6.88e-2)" "unprognostic (8.07e-2)" "unprognostic (1.24e-1)" "unprognostic (1.19e-1)" "unprognostic (6.49e-2)" "unprognostic (5.51e-2)" "unprognostic (2.88e-1)" "unprognostic (1.50e-1)" "unprognostic (8.78e-3)" "unprognostic (9.58e-2)" "unprognostic (7.65e-6)" "unprognostic (8.59e-2)" "unprognostic (3.29e-1)" "unprognostic (2.32e-2)" "unprognostic (2.22e-2)" ARHGDIA "GDIA1, RHOGDI" ENSG00000141522 "Rho GDP dissociation inhibitor alpha" P52565 17 81867721-81871378 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010005, HPA021407" Approved Supported Cytosol NA NA 21000000 "Cluster 25: Non-specific - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 27: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 45: Non-specific - Mixed function" 7 Cytosol "CAB010005: AB_2227516, HPA021407: AB_1856267" "unprognostic (1.08e-1)" "unprognostic (2.29e-2)" "unprognostic (1.13e-1)" "unprognostic (3.05e-2)" "unprognostic (5.00e-2)" "unprognostic (8.39e-3)" "unprognostic (1.39e-2)" "prognostic unfavorable (7.63e-4)" "unprognostic (5.32e-2)" "unprognostic (4.67e-2)" "unprognostic (2.67e-2)" "unprognostic (6.62e-2)" "unprognostic (1.82e-1)" "unprognostic (1.34e-1)" "unprognostic (1.76e-1)" "unprognostic (3.29e-1)" "unprognostic (6.88e-3)" ARPC1A "Arc40, SOP2Hs, SOP2L" ENSG00000241685 "Actin related protein 2/3 complex subunit 1A" Q92747 7 99325898-99366262 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 380.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004334 Approved Approved "Cell Junctions,Cytosol" NA NA 760000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 30: Heart muscle - Heart development" "Cluster 14: Neurons - Synaptic function" "Cluster 39: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" 7 "Cell Junctions" Cytosol "HPA004334: AB_1078215" "unprognostic (1.31e-1)" "unprognostic (1.58e-1)" "unprognostic (6.22e-3)" "unprognostic (1.93e-2)" "unprognostic (8.38e-3)" "unprognostic (1.95e-2)" "prognostic unfavorable (4.70e-4)" "unprognostic (2.52e-2)" "unprognostic (2.16e-1)" "unprognostic (1.29e-1)" "unprognostic (1.73e-2)" "unprognostic (3.89e-2)" "unprognostic (7.88e-2)" "unprognostic (4.45e-2)" "unprognostic (9.15e-2)" "unprognostic (7.07e-2)" "unprognostic (1.83e-1)" ASPH "BAH, CASQ2BP1, HAAH, JCTN" ENSG00000198363 "Aspartate beta-hydroxylase" Q12797 8 61500556-61714640 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Dioxygenase, Oxidoreductase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 372.0" "Cell type enhanced" "Detected in all" "Astrocytes: 347.7;Muller glia cells: 388.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 34.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055161, HPA059303" Uncertain Enhanced "Endoplasmic reticulum" NA NA 1100000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 3: Non-specific - Unknown function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 7: Liver cancer - Metabolism" "Cluster 45: Non-specific - Mixed function" 1 "Endoplasmic reticulum" "HPA055161: AB_2682721, HPA059303: AB_2683973" "unprognostic (8.07e-2)" "prognostic unfavorable (8.07e-5)" "unprognostic (1.73e-2)" "unprognostic (4.48e-2)" "unprognostic (2.32e-1)" "unprognostic (1.85e-2)" "unprognostic (2.82e-2)" "prognostic unfavorable (3.61e-4)" "unprognostic (6.39e-2)" "unprognostic (3.64e-1)" "prognostic unfavorable (1.75e-4)" "unprognostic (9.50e-2)" "prognostic unfavorable (1.57e-5)" "unprognostic (8.96e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (4.24e-4)" "unprognostic (2.74e-2)" ATF4 "CREB-2, TAXREB67, TXREB" ENSG00000128272 "Activating transcription factor 4" P18848 22 39519695-39522683 "Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011596, HPA062987" Approved Supported Nucleoplasm NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 45: Non-specific - Mixed function" 34 Nucleoplasm "CAB011596: AB_725569, HPA062987: " "unprognostic (2.51e-2)" "unprognostic (7.36e-2)" "unprognostic (1.79e-1)" "unprognostic (1.09e-1)" "unprognostic (4.45e-2)" "unprognostic (6.17e-2)" "prognostic unfavorable (4.07e-4)" "unprognostic (4.43e-2)" "unprognostic (1.97e-1)" "unprognostic (5.16e-2)" "unprognostic (1.50e-1)" "unprognostic (4.41e-1)" "prognostic unfavorable (9.77e-5)" "unprognostic (7.06e-2)" "unprognostic (9.78e-2)" "unprognostic (6.40e-2)" "unprognostic (1.95e-1)" BACE2 "AEPLC, ALP56, CEAP1, DRAP" ENSG00000182240 "Beta-secretase 2" Q9Y5Z0 21 41167801-41282530 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 26.0" "Cell type enhanced" "Detected in many" "Melanocytes: 261.1;Mucus glandular cells: 248.8;Syncytiotrophoblasts: 521.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 2.9;eosinophil: 5.2" "Lineage enriched" "Detected in single" 8 "granulocytes: 5.2" "Cancer enhanced" "Detected in many" "skin cancer: 55.9" "Adipose visceral - Adipose progenitor cells, Lung - Fibroblast_2, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035416 Approved "Intracellular and membrane" Enzyme NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 48: Stomach - Proteolysis" "Cluster 27: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 45: Non-specific - Mixed function" 14 "HPA035416: AB_2732467" "unprognostic (1.71e-2)" "prognostic unfavorable (1.11e-4)" "unprognostic (5.23e-2)" "unprognostic (8.12e-3)" "prognostic unfavorable (5.86e-4)" "unprognostic (1.52e-2)" "unprognostic (2.58e-2)" "unprognostic (2.64e-3)" "unprognostic (7.24e-2)" "unprognostic (2.49e-1)" "unprognostic (3.46e-2)" "unprognostic (8.50e-2)" "unprognostic (1.22e-1)" "unprognostic (4.04e-1)" "unprognostic (2.10e-1)" "unprognostic (2.76e-2)" "unprognostic (5.83e-2)" BCL2L1 "Bcl-X, bcl-xL, bcl-xS, BCL2L, BCLX, PPP1R52" ENSG00000171552 "BCL2 like 1" Q07817 20 31664452-31723989 "Cancer-related genes, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Apoptosis, Endocytosis" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 219.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035734, CAB072801" Approved Approved Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 22 Mitochondria "CAB072801: , HPA035734: AB_2674757" "unprognostic (2.29e-1)" "unprognostic (5.40e-3)" "unprognostic (1.78e-2)" "prognostic unfavorable (9.10e-4)" "unprognostic (1.37e-1)" "unprognostic (1.09e-1)" "unprognostic (5.04e-2)" "unprognostic (7.82e-3)" "prognostic favorable (9.57e-4)" "unprognostic (1.67e-1)" "prognostic unfavorable (5.87e-4)" "unprognostic (1.06e-1)" "prognostic favorable (8.89e-5)" "unprognostic (9.67e-2)" "unprognostic (3.03e-2)" "unprognostic (2.02e-2)" "unprognostic (3.32e-2)" BCL2L15 "Bfk, C1orf178, FLJ22588" ENSG00000188761 "BCL2 like 15" Q5TBC7 1 113876816-113887581 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 13.1;intestine: 42.0;stomach 1: 17.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 108.9;Exocrine glandular cells: 93.4;Gastric mucus-secreting cells: 35.4;Intestinal goblet cells: 39.8;Proximal enterocytes: 158.6;Undifferentiated cells: 41.8" "Cancer enhanced" "Detected in many" "colorectal cancer: 10.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Bile duct cancer: 13.6;colorectal cancer: 16.7;Gastric cancer: 6.7;pancreatic cancer: 4.8" "Colon - Colon enterocytes, Pancreas - Ductal cells, Stomach - Gastric mucous cells" "Region enriched" "Detected in some" 32 "cerebellum: 32.9" "Low region specificity" "Detected in all" "HPA029732, HPA029733" Enhanced NA NA "Cluster 45: Intestine - Digestion" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Non-specific - Mixed function" 6 "HPA029732: AB_10599615, HPA029733: AB_10600422" "unprognostic (5.96e-2)" "unprognostic (6.41e-3)" "unprognostic (5.82e-2)" "prognostic favorable (5.63e-4)" "unprognostic (2.16e-1)" "unprognostic (6.23e-3)" "unprognostic (4.97e-4)" "unprognostic (1.74e-1)" "unprognostic (2.95e-1)" "unprognostic (1.46e-2)" "unprognostic (1.27e-2)" "unprognostic (1.49e-1)" "unprognostic (2.42e-7)" "unprognostic (5.20e-2)" "unprognostic (2.24e-2)" "unprognostic (9.04e-3)" "unprognostic (4.27e-2)" BLACAT1 "linc-UBC1, LINC00912, onco-lncRNA-30" ENSG00000281406 "BLACAT1 overlapping LEMD1 locus" 1 205434885-205457091 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "epididymis: 3.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 6.1;Collecting duct cells: 9.7;Granulosa cells: 4.0;Horizontal cells: 3.8;Mucus glandular cells: 3.1;Salivary duct cells: 2.5;Sertoli cells: 2.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Prostate - Urothelial cells, Testis - Sertoli cells" NA NA "Cluster 49: Hindbrain - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 45: Non-specific - Mixed function" "unprognostic (3.01e-2)" "unprognostic (7.43e-2)" "unprognostic (1.69e-1)" "unprognostic (2.87e-3)" "unprognostic (5.22e-2)" "unprognostic (7.97e-2)" "unprognostic (5.59e-2)" "unprognostic (5.02e-2)" "unprognostic (2.13e-2)" "unprognostic (7.37e-3)" "unprognostic (5.36e-2)" "unprognostic (6.23e-7)" "unprognostic (3.09e-2)" "unprognostic (6.78e-2)" "unprognostic (1.84e-2)" "unprognostic (4.59e-1)" BMAL2 "ARNTL2, bHLHe6, CLIF, MOP9, PASD9" ENSG00000029153 "Basic helix-loop-helix ARNT like 2" Q8WYA1 12 27332836-27425289 "Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 26.9;lymphoid tissue: 21.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 76.1;Exocrine glandular cells: 27.3;Gastric mucus-secreting cells: 25.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA059074 Uncertain Supported Nucleoplasm,Nucleoli No No "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Non-specific - Mixed function" "Nucleoplasm, Nucleoli" "HPA059074: AB_2683897" "unprognostic (6.86e-2)" "unprognostic (6.16e-2)" "unprognostic (5.88e-3)" "unprognostic (1.01e-2)" "unprognostic (3.34e-2)" "unprognostic (1.34e-1)" "unprognostic (2.84e-3)" "unprognostic (2.97e-3)" "unprognostic (1.49e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (5.29e-6)" "unprognostic (5.26e-2)" "prognostic unfavorable (1.56e-5)" "unprognostic (7.81e-3)" "unprognostic (2.77e-1)" "unprognostic (1.21e-1)" "unprognostic (2.79e-1)" BOLA2B ENSG00000169627 "BolA family member 2B" Q9H3K6 16 30192932-30194306 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 41.5;Distal tubular cells: 83.0;Proximal enterocytes: 49.4;Proximal tubular cells: 41.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA045380, HPA046696" Supported Uncertain Nucleoplasm NA NA 390000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 23: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 45: Non-specific - Mixed function" 1 Nucleoplasm "HPA045380: AB_2679301, HPA046696: AB_2679757" "unprognostic (2.49e-1)" "unprognostic (4.60e-3)" "unprognostic (8.49e-2)" "unprognostic (3.02e-3)" "unprognostic (9.80e-4)" "unprognostic (1.22e-1)" "unprognostic (3.75e-2)" "unprognostic (1.25e-1)" "unprognostic (3.08e-2)" "unprognostic (2.24e-2)" "unprognostic (1.26e-1)" "unprognostic (5.75e-2)" "unprognostic (1.70e-1)" "unprognostic (2.94e-1)" "unprognostic (5.29e-1)" "unprognostic (2.21e-2)" "unprognostic (4.91e-3)" BORCS8 MEF2BNB ENSG00000254901 "BLOC-1 related complex subunit 8" Q96FH0 19 19176903-19192591 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045700 Approved Approved Vesicles NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 33: Brain - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 23: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" 6 Vesicles "HPA045700: AB_10968570" "unprognostic (4.23e-3)" "unprognostic (1.61e-2)" "unprognostic (2.75e-1)" "unprognostic (3.58e-2)" "unprognostic (2.28e-1)" "unprognostic (3.01e-2)" "unprognostic (5.51e-2)" "unprognostic (5.81e-3)" "unprognostic (1.78e-2)" "unprognostic (6.82e-2)" "prognostic favorable (4.05e-5)" "unprognostic (6.20e-2)" "unprognostic (1.76e-1)" "unprognostic (1.22e-1)" "unprognostic (3.16e-1)" "unprognostic (1.38e-2)" "unprognostic (3.00e-2)" BRK1 "C3orf10, HSPC300, MDS027" ENSG00000254999 "BRICK1 subunit of SCAR/WAVE actin nucleating complex" Q8WUW1 3 10115675-10127190 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 2572.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060391 Approved "Nuclear speckles,Cell Junctions" NA NA 170000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 35: Non-specific - Mitochondria" "Cluster 14: Neurons - Synaptic function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" 46 "Nuclear speckles" "Cell Junctions" "HPA060391: AB_2684272" "unprognostic (4.99e-2)" "unprognostic (3.48e-2)" "unprognostic (2.64e-1)" "unprognostic (3.83e-2)" "unprognostic (2.91e-1)" "unprognostic (9.60e-2)" "prognostic unfavorable (5.76e-5)" "unprognostic (2.49e-2)" "unprognostic (2.89e-1)" "unprognostic (1.09e-1)" "unprognostic (1.89e-1)" "unprognostic (1.37e-1)" "unprognostic (7.14e-3)" "unprognostic (1.12e-1)" "unprognostic (9.40e-2)" "unprognostic (4.35e-2)" "unprognostic (7.75e-3)" BRS3 "BB3, BB3R, BBR3" ENSG00000102239 "Bombesin receptor subtype 3" P32247 X 136487947-136493780 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "epididymis: 25.1" "Cell type enhanced" "Detected in some" "Pancreatic endocrine cells: 5.1;Spermatogonia: 1.5" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hypothalamus: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Alpha cells" "Region enriched" "Detected in some" 4 "hypothalamus: 6.1" "Region enhanced" "Detected in single" "basal ganglia: 2.4" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 40: Non-specific - Unknown function" "Cluster 45: Non-specific - Mixed function" "unprognostic (1.49e-1)" "unprognostic (1.31e-1)" "unprognostic (2.07e-1)" "unprognostic (1.79e-2)" "unprognostic (3.73e-6)" "unprognostic (1.59e-1)" "unprognostic (1.86e-1)" "unprognostic (5.59e-2)" BZW1 "5MP2, BZAP45, KIAA0005" ENSG00000082153 "Basic leucine zipper and W2 domains 1" Q7L1Q6 2 200810594-200827338 "Predicted intracellular proteins" "Transcription, Transcription regulation, Translation regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1475.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047288, HPA053272" Uncertain Approved Vesicles NA NA 34000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 4: Testis - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 45: Non-specific - Mixed function" 1 Vesicles "HPA047288: , HPA053272: " "unprognostic (2.45e-2)" "prognostic unfavorable (4.28e-4)" "unprognostic (2.08e-3)" "unprognostic (1.56e-2)" "unprognostic (1.93e-1)" "unprognostic (3.31e-3)" "unprognostic (3.98e-3)" "prognostic unfavorable (5.10e-4)" "unprognostic (4.49e-3)" "unprognostic (7.93e-3)" "unprognostic (1.08e-3)" "unprognostic (8.97e-3)" "unprognostic (4.38e-2)" "unprognostic (3.04e-1)" "unprognostic (7.61e-2)" "unprognostic (8.03e-2)" "unprognostic (1.24e-1)" C15orf48 "COXFA4L3, MIR147BHG, MISTRAV, MOCCI, NMES1" ENSG00000166920 "Chromosome 15 open reading frame 48" Q9C002 15 45430579-45448761 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 893.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 4361.0;Enteroendocrine cells: 1468.6;Exocrine glandular cells: 2025.4;Intestinal goblet cells: 1372.4;Langerhans cells: 2561.4;Paneth cells: 2158.2;Proximal enterocytes: 3050.5;Undifferentiated cells: 1467.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 6.3" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.3;intermediate monocyte: 1.6;myeloid DC: 1.3" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 606.0" "Colon - Colon enterocytes, Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA012943 Enhanced NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 45: Intestine - Digestion" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 1 "HPA012943: AB_2668774" "unprognostic (5.29e-3)" "unprognostic (1.76e-1)" "unprognostic (2.08e-1)" "unprognostic (7.83e-2)" "unprognostic (1.17e-1)" "unprognostic (9.74e-3)" "unprognostic (1.48e-3)" "unprognostic (1.28e-3)" "unprognostic (1.59e-1)" "unprognostic (1.15e-1)" "unprognostic (4.93e-3)" "unprognostic (5.95e-2)" "unprognostic (8.86e-2)" "unprognostic (2.37e-1)" "unprognostic (6.51e-2)" "unprognostic (1.39e-1)" "unprognostic (3.66e-1)" C19orf33 "H2RSP, IMUP, IMUP-1, IMUP-2" ENSG00000167644 "Chromosome 19 open reading frame 33" Q9GZP8 19 38304164-38305006 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 500.9;skin 1: 320.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 2497.3;Intestinal goblet cells: 784.7;Paneth cells: 1264.3;Proximal enterocytes: 1796.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 10 "myeloid DC: 22.3" "Lineage enriched" "Detected in many" 10 "dendritic cells: 22.3" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Lung - Alveolar cells type 1, Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "HPA054406, HPA059696" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" No No 460000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 47: Endothelial cells - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" Nucleoplasm "Plasma membrane, Cytosol" "HPA054406: AB_2682478, HPA059696: AB_2684105" "unprognostic (9.31e-2)" "unprognostic (2.06e-1)" "unprognostic (4.34e-2)" "unprognostic (1.44e-2)" "unprognostic (3.92e-3)" "unprognostic (2.37e-2)" "unprognostic (9.49e-2)" "prognostic unfavorable (5.42e-4)" "unprognostic (2.09e-1)" "unprognostic (1.74e-2)" "prognostic unfavorable (5.05e-4)" "unprognostic (6.92e-2)" "unprognostic (5.50e-2)" "unprognostic (4.82e-2)" "unprognostic (1.61e-1)" "unprognostic (3.63e-2)" "unprognostic (6.01e-2)" C3orf52 "FLJ23186, TTMP" ENSG00000114529 "Chromosome 3 open reading frame 52" Q5BVD1 3 112086335-112131004 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 16.9;skin 1: 25.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 48.1;Basal squamous epithelial cells: 50.5;Gastric mucus-secreting cells: 57.2;Intestinal goblet cells: 64.7;Syncytiotrophoblasts: 81.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Cholangiocyte, Lung - Alveolar cells type 2, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA007678, HPA008119, HPA011968" Uncertain Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 57 "Nucleoplasm, Nuclear bodies, Cytosol" "HPA007678: , HPA008119: AB_1848824, HPA011968: AB_1848826" "unprognostic (8.86e-2)" "unprognostic (1.71e-1)" "unprognostic (3.58e-2)" "unprognostic (7.97e-2)" "unprognostic (1.45e-2)" "unprognostic (3.87e-3)" "unprognostic (3.49e-4)" "unprognostic (2.54e-1)" "unprognostic (1.39e-2)" "unprognostic (2.30e-1)" "prognostic unfavorable (3.85e-4)" "unprognostic (2.71e-2)" "unprognostic (3.76e-6)" "unprognostic (3.14e-1)" "unprognostic (2.05e-1)" "unprognostic (1.75e-2)" "unprognostic (9.59e-2)" C4orf19 FLJ11017 ENSG00000154274 "Chromosome 4 open reading frame 19" Q8IY42 4 37453925-37623495 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 34.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 83.9;Distal enterocytes: 109.7;Enteroendocrine cells: 76.0;Exocrine glandular cells: 114.3;Proximal enterocytes: 105.0;Syncytiotrophoblasts: 97.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 8.4" "Lineage enriched" "Detected in many" 5 "granulocytes: 8.4" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Colon - Colon enterocytes, Liver - Hepatocytes, Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043458, HPA052894" Enhanced Approved "Nucleoplasm,Cell Junctions" No No "Cluster 21: Neutrophils - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 27: Breast cancer - Unknown function" "Cluster 45: Non-specific - Mixed function" 4 Nucleoplasm "Cell Junctions" "HPA043458: AB_10960696, HPA052894: AB_2681982" "unprognostic (8.83e-2)" "unprognostic (7.86e-2)" "unprognostic (3.00e-3)" "unprognostic (2.04e-2)" "unprognostic (2.23e-1)" "unprognostic (3.59e-3)" "unprognostic (5.55e-2)" "unprognostic (2.29e-1)" "unprognostic (6.66e-2)" "unprognostic (9.96e-2)" "unprognostic (1.35e-1)" "unprognostic (4.38e-2)" "prognostic favorable (1.49e-11)" "unprognostic (1.33e-1)" "unprognostic (1.60e-1)" "unprognostic (1.63e-3)" "unprognostic (8.19e-3)" C6orf132 bA7K24.2 ENSG00000188112 "Chromosome 6 open reading frame 132" Q5T0Z8 6 42092233-42142620 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 152.6;skin 1: 71.3" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 106.5;Late spermatids: 148.4;Proximal enterocytes: 108.0;Suprabasal keratinocytes: 163.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 95.2" "Adipose visceral - Mesothelial cells, Liver - Cholangiocyte, Skin - Keratinocyte (other), Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA044588 Enhanced Approved "Golgi apparatus,Cytosol" NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 51: Neurons - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 45: Non-specific - Mixed function" "Golgi apparatus, Cytosol" "HPA044588: AB_10794293" "unprognostic (7.09e-2)" "unprognostic (8.88e-2)" "unprognostic (1.20e-1)" "unprognostic (1.24e-3)" "unprognostic (1.60e-2)" "unprognostic (1.24e-2)" "unprognostic (1.15e-1)" "unprognostic (6.78e-2)" "unprognostic (1.59e-1)" "unprognostic (2.30e-2)" "prognostic unfavorable (4.90e-4)" "unprognostic (1.31e-1)" "unprognostic (4.26e-3)" "unprognostic (1.04e-2)" "unprognostic (5.53e-2)" "unprognostic (2.47e-2)" "unprognostic (1.30e-1)" CAP1 CAP ENSG00000131236 "Cyclase associated actin cytoskeleton regulatory protein 1" Q01518 1 40040233-40072649 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Neutrophil_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030124 Approved Approved Cytosol NA NA 73000000 "Cluster 25: Non-specific - Unknown function" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 27: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 45: Non-specific - Mixed function" 1 Cytosol "HPA030124: AB_10600799" "unprognostic (1.80e-3)" "unprognostic (1.23e-3)" "unprognostic (5.68e-2)" "unprognostic (1.04e-1)" "unprognostic (6.50e-2)" "unprognostic (1.37e-2)" "prognostic unfavorable (1.44e-6)" "unprognostic (5.37e-2)" "unprognostic (4.87e-1)" "unprognostic (1.98e-1)" "unprognostic (3.33e-3)" "unprognostic (1.09e-1)" "unprognostic (6.22e-2)" "unprognostic (1.39e-1)" "unprognostic (7.08e-2)" "unprognostic (1.26e-1)" "unprognostic (3.44e-1)" CAPN1 "CANP, CANPL1, muCANP, muCL" ENSG00000014216 "Calpain 1" P07384 11 65180566-65212006 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 268.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005992 Enhanced Supported Cytosol NA NA 9100000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 7 Cytosol "HPA005992: AB_1845924" "unprognostic (2.07e-1)" "unprognostic (2.15e-1)" "unprognostic (2.69e-1)" "unprognostic (1.40e-1)" "unprognostic (4.06e-2)" "unprognostic (1.10e-1)" "unprognostic (1.91e-2)" "unprognostic (2.48e-2)" "unprognostic (7.23e-2)" "unprognostic (2.23e-2)" "prognostic unfavorable (4.30e-4)" "unprognostic (3.33e-1)" "prognostic favorable (7.06e-8)" "unprognostic (5.70e-3)" "unprognostic (1.51e-1)" "unprognostic (1.86e-1)" "unprognostic (2.98e-1)" CAPN2 "CANPL2, CANPml, mCANP" ENSG00000162909 "Calpain 2" P17655 1 223701593-223776018 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 508.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024470 Approved Approved Supported Cytosol NA NA 2800000 "Cluster 33: Non-specific - ATP binding" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 19: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Non-specific - Mixed function" 8 Cytosol "HPA024470: AB_1845925" "unprognostic (2.77e-2)" "unprognostic (1.27e-3)" "unprognostic (2.03e-1)" "unprognostic (3.39e-2)" "unprognostic (2.12e-1)" "unprognostic (3.32e-2)" "unprognostic (1.59e-1)" "unprognostic (1.10e-1)" "unprognostic (2.85e-1)" "unprognostic (1.96e-1)" "prognostic unfavorable (2.50e-4)" "unprognostic (1.21e-1)" "prognostic favorable (2.19e-4)" "unprognostic (1.61e-1)" "unprognostic (2.63e-1)" "unprognostic (2.62e-1)" "prognostic unfavorable (6.21e-4)" CAPNS1 "30K, CANP, CANPS, CAPN4, CDPS" ENSG00000126247 "Calpain small subunit 1" P04632 19 36139953-36150353 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006872 Approved Approved Nucleoplasm,Cytosol NA NA 9000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 23: Non-specific - Cellular respiration" "Cluster 1: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" 5 "Nucleoplasm, Cytosol" "HPA006872: AB_1078382" "unprognostic (1.23e-1)" "unprognostic (1.25e-1)" "unprognostic (2.94e-2)" "unprognostic (1.19e-2)" "unprognostic (1.91e-1)" "unprognostic (2.03e-1)" "unprognostic (2.82e-3)" "unprognostic (1.25e-3)" "unprognostic (2.04e-2)" "unprognostic (6.40e-2)" "unprognostic (1.17e-1)" "unprognostic (5.53e-2)" "unprognostic (7.10e-3)" "unprognostic (1.37e-2)" "unprognostic (1.79e-2)" "unprognostic (1.51e-1)" "unprognostic (4.72e-2)" CAV2 CAV ENSG00000105971 "Caveolin 2" P51636 7 116287380-116508541 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 219.3" "Cell type enhanced" "Detected in many" "Adipocytes: 286.6;Alveolar cells type 1: 672.1;Basal keratinocytes: 318.9;Basal respiratory cells: 313.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 114 "basophil: 97.0" "Lineage enriched" "Detected in single" 433 "granulocytes: 97.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013488, HPA044810" Enhanced Approved Vesicles NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 7: Adipose tissue - Mixed function" "Cluster 27: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 3 Vesicles "CAB013488: AB_2533493, HPA044810: AB_2679098" "unprognostic (4.76e-2)" "unprognostic (3.91e-3)" "unprognostic (4.56e-2)" "unprognostic (2.91e-1)" "unprognostic (5.09e-3)" "prognostic unfavorable (5.80e-5)" "unprognostic (3.66e-2)" "unprognostic (2.27e-2)" "unprognostic (3.81e-1)" "unprognostic (3.34e-1)" "prognostic unfavorable (1.21e-4)" "unprognostic (6.32e-2)" "unprognostic (3.44e-3)" "unprognostic (7.84e-3)" "unprognostic (2.88e-1)" "unprognostic (2.42e-1)" "unprognostic (6.34e-3)" CBFB PEBP2B ENSG00000067955 "Core-binding factor subunit beta" Q13951 16 67028984-67101058 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038852 Uncertain Approved Nucleoplasm,Cytosol NA NA 18000 "Cluster 32: Basophils - Transcription" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 45: Non-specific - Mixed function" 3 Cytosol Nucleoplasm "HPA038852: AB_10795358" "unprognostic (1.05e-1)" "unprognostic (1.18e-2)" "unprognostic (1.30e-1)" "unprognostic (3.22e-2)" "unprognostic (4.66e-2)" "unprognostic (3.80e-3)" "prognostic unfavorable (2.83e-4)" "unprognostic (1.63e-2)" "unprognostic (1.47e-1)" "unprognostic (1.11e-1)" "unprognostic (4.46e-3)" "unprognostic (1.88e-2)" "prognostic unfavorable (2.89e-8)" "unprognostic (1.03e-1)" "unprognostic (4.31e-2)" "unprognostic (1.37e-1)" "unprognostic (1.20e-1)" CCDC124 "Lso2, oxs1" ENSG00000007080 "Coiled-coil domain containing 124" Q96CT7 19 17933015-17943991 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041708, HPA046765" Supported Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 23: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" "Plasma membrane, Cytosol" "HPA041708: AB_2677628, HPA046765: AB_2679793" "unprognostic (9.39e-2)" "unprognostic (1.36e-1)" "unprognostic (2.51e-1)" "unprognostic (1.70e-1)" "unprognostic (2.16e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.68e-4)" "unprognostic (4.32e-2)" "unprognostic (1.02e-1)" "unprognostic (3.20e-2)" "unprognostic (1.34e-1)" "unprognostic (2.04e-2)" "unprognostic (1.10e-1)" "unprognostic (2.50e-1)" "unprognostic (2.19e-1)" "unprognostic (3.71e-2)" "unprognostic (3.22e-1)" CCDC68 SE57-1 ENSG00000166510 "Coiled-coil domain containing 68" Q9H2F9 18 54901509-54959461 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 24.1;placenta: 31.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 76.5;Early spermatids: 122.3;Endothelial cells: 47.3;Paneth cells: 48.7;Proximal enterocytes: 56.1" "Cancer enhanced" "Detected in many" "stomach cancer: 4.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA040865, HPA048197" Supported Approved "Golgi apparatus,Cytosol" No NA "Cluster 25: Small intestine - Absorption" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 4 "Golgi apparatus" Cytosol "HPA040865: AB_2677176, HPA048197: AB_2680310" "unprognostic (1.36e-2)" "prognostic unfavorable (4.50e-4)" "unprognostic (1.47e-3)" "unprognostic (7.38e-2)" "unprognostic (1.77e-1)" "unprognostic (5.91e-2)" "unprognostic (2.65e-2)" "unprognostic (6.29e-2)" "unprognostic (2.71e-1)" "unprognostic (1.16e-1)" "unprognostic (1.15e-3)" "unprognostic (1.13e-1)" "prognostic favorable (5.28e-4)" "unprognostic (1.77e-2)" "unprognostic (9.71e-2)" "unprognostic (6.12e-2)" "unprognostic (2.38e-1)" CCDC9B "C15orf52, FLJ43339" ENSG00000188549 "Coiled-coil domain containing 9B" Q6ZUT6 15 40331452-40340939 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 64.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 40.4;Ductal cells: 29.4;Mucus glandular cells: 24.7;Sertoli cells: 29.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Pancreas - Ductal cells, Prostate - Smooth muscle cells, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040484, HPA041834" Approved Approved Nucleoplasm,Cytosol NA NA 77000 "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" "Nucleoplasm, Cytosol" "HPA040484: AB_10794742, HPA041834: AB_10795643" "unprognostic (5.57e-3)" "unprognostic (1.85e-1)" "unprognostic (2.60e-3)" "unprognostic (2.33e-2)" "unprognostic (1.48e-2)" "unprognostic (2.68e-1)" "unprognostic (1.86e-2)" "unprognostic (1.01e-1)" "unprognostic (1.50e-1)" "unprognostic (7.06e-3)" "unprognostic (1.51e-2)" "unprognostic (2.50e-1)" "unprognostic (1.04e-3)" "unprognostic (1.55e-1)" "unprognostic (3.48e-1)" "unprognostic (1.50e-2)" "unprognostic (9.68e-2)" CCNC CycC ENSG00000112237 "Cyclin C" P24863 6 99542387-99568825 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Cyclin, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010499, HPA069322" Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 68: Non-specific - Protein processing" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 28: Non-specific - Nuclear processes" "Cluster 45: Non-specific - Mixed function" 69 Nucleoplasm Cytosol "CAB010499: AB_2244021, HPA069322: AB_2686120" "unprognostic (1.48e-2)" "unprognostic (1.21e-2)" "unprognostic (1.85e-3)" "unprognostic (6.34e-2)" "unprognostic (1.92e-2)" "unprognostic (1.95e-3)" "unprognostic (2.09e-1)" "unprognostic (3.86e-1)" "unprognostic (1.10e-1)" "unprognostic (1.64e-2)" "unprognostic (1.92e-1)" "unprognostic (7.10e-2)" "prognostic favorable (8.12e-4)" "unprognostic (1.91e-1)" "unprognostic (1.21e-1)" "unprognostic (1.41e-1)" "unprognostic (3.83e-2)" CCND1 "BCL1, D11S287E, PRAD1, U21B31" ENSG00000110092 "Cyclin D1" P24385 11 69641156-69654474 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, DNA damage, Transcription, Transcription regulation" "Cyclin, Repressor" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 896.3;Basal respiratory cells: 481.5;Secretory cells: 448.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000024, HPA027802" Uncertain Supported Nucleoplasm Yes No "Cluster 32: Basophils - Transcription" "Cluster 13: Skin - Cornification" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 45: Non-specific - Mixed function" 13 Nucleoplasm "CAB000024: AB_563678, HPA027802: AB_2672390" "unprognostic (4.90e-2)" "unprognostic (1.54e-1)" "unprognostic (7.62e-2)" "unprognostic (1.39e-2)" "unprognostic (2.18e-1)" "prognostic unfavorable (5.51e-4)" "unprognostic (1.38e-1)" "unprognostic (2.53e-2)" "unprognostic (9.46e-2)" "unprognostic (4.84e-3)" "prognostic unfavorable (1.96e-4)" "unprognostic (4.39e-2)" "unprognostic (2.61e-3)" "unprognostic (4.38e-3)" "unprognostic (1.16e-1)" "unprognostic (6.40e-3)" "unprognostic (2.57e-1)" CCZ1 "C7orf28A, CCZ1A, CGI-43" ENSG00000122674 "CCZ1 homolog, vacuolar protein trafficking and biogenesis associated" P86791 7 5898725-5926550 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "HPA045114, HPA050006" Uncertain Enhanced Vesicles NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 66: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 45: Non-specific - Mixed function" Vesicles "HPA045114: AB_2679219, HPA050006: AB_2680989" "unprognostic (1.91e-1)" "unprognostic (2.97e-3)" "unprognostic (3.15e-2)" "unprognostic (1.25e-2)" "unprognostic (1.82e-1)" "unprognostic (5.35e-2)" "unprognostic (3.74e-3)" "unprognostic (4.10e-1)" "unprognostic (9.25e-3)" "unprognostic (7.66e-2)" "unprognostic (6.64e-2)" "unprognostic (2.67e-2)" "unprognostic (5.27e-3)" "unprognostic (3.25e-1)" "unprognostic (1.31e-1)" "unprognostic (1.74e-1)" "unprognostic (4.41e-1)" CD151 "PETA-3, RAPH, SFA-1, TSPAN24" ENSG00000177697 "CD151 molecule (Raph blood group)" P48509 11 832887-839831 "Blood group antigen proteins, CD markers, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction" "Blood group antigen" "Deafness, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002428, HPA011906" Supported NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" 8 "CAB002428: AB_564129, HPA011906: AB_1846245" "unprognostic (1.50e-1)" "unprognostic (1.12e-2)" "unprognostic (5.47e-2)" "unprognostic (5.45e-3)" "unprognostic (4.10e-3)" "unprognostic (2.45e-2)" "prognostic unfavorable (5.58e-4)" "prognostic unfavorable (9.46e-4)" "unprognostic (5.47e-2)" "unprognostic (2.41e-1)" "unprognostic (1.02e-3)" "unprognostic (3.31e-1)" "unprognostic (4.39e-2)" "unprognostic (6.23e-3)" "unprognostic (3.24e-1)" "prognostic favorable (6.92e-4)" "unprognostic (7.83e-2)" CD47 "IAP, MER6, OA3" ENSG00000196776 "CD47 molecule" Q08722 3 108043091-108091862 "CD markers, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Angiogenesis, Apoptosis, Cell adhesion, Inflammatory response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 484.0;Ductal cells: 550.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016055, HPA044659" Approved Supported "Vesicles,Plasma membrane" NA NA 49000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 40: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 45: Non-specific - Mixed function" 1 "Plasma membrane" Vesicles "CAB016055: AB_627086, HPA044659: AB_2679040" "unprognostic (3.54e-2)" "unprognostic (4.74e-2)" "unprognostic (3.19e-2)" "prognostic unfavorable (2.44e-4)" "unprognostic (4.49e-2)" "unprognostic (2.14e-1)" "unprognostic (2.05e-3)" "unprognostic (8.77e-3)" "unprognostic (7.35e-2)" "unprognostic (1.53e-1)" "unprognostic (1.69e-2)" "unprognostic (2.87e-1)" "prognostic unfavorable (1.69e-4)" "unprognostic (7.37e-2)" "unprognostic (3.78e-1)" "prognostic favorable (7.29e-5)" "unprognostic (1.83e-1)" CD59 "16.3A5, EJ16, EJ30, EL32, G344, MIC11, MIN1, MIN2, MIN3, MSK21, p18-20" ENSG00000085063 "CD59 molecule (CD59 blood group)" P13987 11 33703010-33736479 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ductal cells: 1341.1;Melanocytes: 1613.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001448, HPA026494" Supported Uncertain "Golgi apparatus,Vesicles" "Intracellular and membrane" "No annotated function" NA NA 58000000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 45: Non-specific - Mixed function" 3 "Golgi apparatus, Vesicles" "CAB001448: AB_563604, HPA026494: AB_1846321" "unprognostic (2.07e-2)" "prognostic unfavorable (3.81e-5)" "unprognostic (7.40e-2)" "unprognostic (1.14e-2)" "unprognostic (2.11e-2)" "prognostic unfavorable (3.10e-5)" "unprognostic (5.65e-2)" "unprognostic (1.46e-1)" "unprognostic (4.47e-2)" "unprognostic (2.98e-1)" "prognostic unfavorable (2.92e-5)" "unprognostic (1.66e-2)" "prognostic favorable (1.39e-10)" "prognostic unfavorable (9.03e-4)" "unprognostic (1.31e-1)" "unprognostic (1.03e-2)" "unprognostic (3.09e-1)" CD63 "ME491, MLA1, TSPAN30" ENSG00000135404 "CD63 molecule" P08962 12 55725323-55729707 "CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 1861.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010088, CAB026356, HPA073506" Supported Supported Vesicles "Intracellular and membrane" Transport NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 12: Non-specific - Vasculature" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 45: Non-specific - Mixed function" 3 Vesicles "CAB026356: AB_629864, HPA010088: AB_1846323, HPA073506: " "unprognostic (8.76e-3)" "unprognostic (8.81e-2)" "unprognostic (1.27e-1)" "unprognostic (1.28e-3)" "unprognostic (9.48e-2)" "unprognostic (3.66e-3)" "prognostic unfavorable (1.37e-4)" "unprognostic (1.11e-1)" "unprognostic (6.50e-2)" "unprognostic (1.08e-1)" "unprognostic (1.66e-2)" "unprognostic (3.10e-1)" "unprognostic (2.70e-2)" "unprognostic (4.82e-2)" "unprognostic (5.21e-2)" "unprognostic (1.85e-3)" "unprognostic (9.02e-2)" CDC37 P50CDC37 ENSG00000105401 "Cell division cycle 37, HSP90 cochaperone" Q16543 19 10391133-10420121 "Cancer-related genes, Predicted intracellular proteins, Transporters" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003928, CAB004214" Supported Supported Cytosol NA NA 610000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 79: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 23: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" 124 Cytosol "CAB004214: AB_627232, HPA003928: AB_1846373" "unprognostic (2.40e-1)" "unprognostic (1.06e-1)" "unprognostic (1.27e-1)" "unprognostic (2.33e-2)" "unprognostic (2.46e-3)" "unprognostic (6.21e-2)" "unprognostic (1.37e-1)" "unprognostic (7.90e-2)" "unprognostic (1.25e-1)" "unprognostic (7.61e-3)" "unprognostic (1.96e-2)" "unprognostic (1.82e-2)" "unprognostic (1.84e-2)" "prognostic favorable (2.33e-4)" "unprognostic (5.80e-2)" "unprognostic (1.23e-1)" "unprognostic (3.02e-2)" CDC42 "CDC42Hs, G25K" ENSG00000070831 "Cell division cycle 42" P60953 1 22052627-22101360 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" Hydrolase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004360, HPA069590" Approved Supported "Microtubules,Cytokinetic bridge" Yes No 2700000 "Cluster 28: Neutrophils - Unknown function" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 45: Non-specific - Mixed function" 31 "Microtubules, Cytokinetic bridge" "CAB004360: AB_627233, HPA069590: AB_2732138" "unprognostic (9.40e-2)" "unprognostic (1.37e-1)" "unprognostic (9.45e-3)" "unprognostic (5.11e-2)" "unprognostic (1.73e-1)" "unprognostic (9.72e-2)" "prognostic unfavorable (5.28e-5)" "unprognostic (1.09e-1)" "unprognostic (7.92e-3)" "unprognostic (1.86e-2)" "unprognostic (3.90e-2)" "unprognostic (9.41e-2)" "unprognostic (9.72e-3)" "unprognostic (2.71e-1)" "unprognostic (3.88e-2)" "unprognostic (6.38e-2)" "unprognostic (2.09e-1)" CDC42EP1 "Borg5, CEP1, MSE55" ENSG00000128283 "CDC42 effector protein 1" Q00587 22 37560480-37569405 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 225.2;Exocrine glandular cells: 165.8;Secretory cells: 201.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 7.3;intermediate monocyte: 1.9;myeloid DC: 2.4" "Group enriched" "Detected in many" 10 "dendritic cells: 2.4;monocytes: 7.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006379, HPA076536" Approved Supported "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 15: Pancreas - Proteolysis" "Cluster 11: White matter - Signal transduction" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Non-specific - Mixed function" 4 "Plasma membrane" "Nucleoplasm, Actin filaments" "HPA006379: AB_1078486, HPA076536: " "unprognostic (1.32e-1)" "unprognostic (1.81e-1)" "unprognostic (2.44e-1)" "unprognostic (3.79e-3)" "unprognostic (5.82e-2)" "unprognostic (4.06e-2)" "unprognostic (4.38e-2)" "unprognostic (5.57e-2)" "unprognostic (9.45e-2)" "unprognostic (1.63e-1)" "unprognostic (2.06e-2)" "unprognostic (1.53e-1)" "unprognostic (1.86e-2)" "unprognostic (2.85e-2)" "unprognostic (3.85e-2)" "unprognostic (3.81e-2)" "unprognostic (1.09e-3)" CDCP1 "CD318, SIMA135" ENSG00000163814 "CUB domain containing protein 1" Q9H5V8 3 45082277-45146422 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 36.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 111.9;Basal respiratory cells: 87.9;Suprabasal keratinocytes: 73.2" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "choroid plexus: 26.9" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.3;NK-cell: 4.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Heart muscle - Macrophages, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA010978, HPA010979, CAB025637" Enhanced "Intracellular and membrane" "No annotated function" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 4 "CAB025637: , HPA010978: AB_1846403, HPA010979: AB_1846401" "unprognostic (9.31e-2)" "unprognostic (4.50e-2)" "unprognostic (1.67e-2)" "unprognostic (2.66e-1)" "unprognostic (1.11e-2)" "unprognostic (1.51e-3)" "unprognostic (2.94e-2)" "prognostic unfavorable (1.41e-5)" "unprognostic (2.15e-1)" "unprognostic (1.00e-1)" "prognostic unfavorable (1.48e-4)" "unprognostic (2.14e-2)" "unprognostic (9.98e-3)" "unprognostic (3.59e-2)" "unprognostic (2.99e-1)" "unprognostic (1.21e-1)" "unprognostic (1.34e-1)" CDKN2A "ARF, CDK4I, CDKN2, CMM2, INK4, INK4a, MLM, MTS1, p14, p14ARF, p16, P16-INK4A, p16INK4a, p19, p19Arf" ENSG00000147889 "Cyclin dependent kinase inhibitor 2A" "P42771, Q8N726" 9 21967752-21995301 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, rRNA processing, Transcription, Transcription regulation, Ubl conjugation pathway" DNA-binding "Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 43.8;pituitary gland: 32.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 157.1;Ciliated cells: 104.1;Club cells: 89.6;Early spermatids: 238.3;Ionocytes: 135.5;Late spermatids: 441.4" "Cancer enhanced" "Detected in all" "cervical cancer: 49.9;ovarian cancer: 57.6" "Region enriched" "Detected in all" 5 "choroid plexus: 57.4" "Immune cell enhanced" "Detected in many" "T-reg: 37.5" "Group enriched" "Detected in many" 6 "B-cells: 15.7;T-cells: 37.5" "Cancer enhanced" "Detected in many" "cervical cancer: 497.2" "Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "CAB000093, CAB000445, CAB018232, HPA073143" Enhanced Supported Nucleoplasm,Cytosol NA NA 18000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 8: Immune cells - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" 21 Nucleoplasm Cytosol "CAB000093: AB_442119, CAB000445: , CAB018232: AB_785018, HPA073143: " "unprognostic (3.41e-2)" "unprognostic (4.51e-2)" "unprognostic (3.00e-3)" "prognostic unfavorable (1.82e-7)" "unprognostic (5.22e-2)" "prognostic favorable (5.19e-4)" "prognostic unfavorable (2.17e-4)" "unprognostic (1.25e-2)" "unprognostic (1.05e-1)" "unprognostic (1.04e-1)" "unprognostic (1.71e-1)" "unprognostic (1.56e-2)" "prognostic unfavorable (5.76e-7)" "unprognostic (9.41e-2)" "unprognostic (1.22e-2)" "unprognostic (3.05e-2)" "unprognostic (3.55e-1)" CEACAM6 "CD66c, NCA" ENSG00000086548 "CEA cell adhesion molecule 6" P40199 19 41750977-41772211 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell adhesion" "Cancer-related genes, Oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 179.4;esophagus: 189.8;intestine: 213.5;lung: 277.7;salivary gland: 172.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 1478.7;Alveolar cells type 2: 210.1;Club cells: 252.8;Distal enterocytes: 438.9;Paneth cells: 364.4" "Group enriched" "Detected in many" 4 "cervical cancer: 139.4;colorectal cancer: 500.8;lung cancer: 344.1;pancreatic cancer: 437.5;stomach cancer: 231.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "pancreatic cancer: 386.8" "Colon - Colon enterocytes, Prostate - Urothelial cells, Skin - Eccrine sweat gland cells" "CAB008370, HPA011041" Enhanced NA NA 86000000 "Cluster 77: Bone marrow - Cell proliferation" "Cluster 34: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 25 "CAB008370: AB_592067, HPA011041: AB_1078481" "unprognostic (1.00e-2)" "unprognostic (2.05e-1)" "unprognostic (2.62e-2)" "unprognostic (8.22e-2)" "unprognostic (1.39e-1)" "unprognostic (9.06e-3)" "unprognostic (2.32e-2)" "unprognostic (1.37e-1)" "unprognostic (2.49e-1)" "unprognostic (5.22e-2)" "unprognostic (3.70e-3)" "unprognostic (1.93e-1)" "unprognostic (2.42e-4)" "unprognostic (4.08e-1)" "unprognostic (8.71e-3)" "unprognostic (2.85e-1)" "unprognostic (7.68e-2)" CFB "BF, BFD, H2-Bf" ENSG00000243649 "Complement factor B" P00751 6 31945650-31952086 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 20 "liver: 2453.1" "Cell type enhanced" "Detected in many" "Ductal cells: 913.7;Exocrine glandular cells: 569.1;Hepatocytes: 199.3;Mesothelial cells: 453.1;Pancreatic endocrine cells: 368.5" "Cancer enhanced" "Detected in all" "liver cancer: 78.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 34.6" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Mesothelial cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA000951, HPA001817, HPA001832, CAB016381" Supported Approved "Endoplasmic reticulum,Vesicles,Cell Junctions" "Secreted to blood" Immunity NA NA 879000000 120000000000 "Cluster 83: Liver - Metabolism" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" "Endoplasmic reticulum, Vesicles" "Cell Junctions" "CAB016381: AB_627562, HPA000951: AB_2797216, HPA001817: AB_1078779, HPA001832: AB_1078778" "prognostic favorable (2.76e-5)" "unprognostic (1.02e-1)" "unprognostic (1.44e-1)" "unprognostic (7.94e-2)" "unprognostic (1.82e-2)" "unprognostic (8.56e-2)" "unprognostic (8.08e-3)" "unprognostic (8.81e-2)" "unprognostic (3.51e-1)" "unprognostic (2.26e-2)" "unprognostic (1.32e-2)" "unprognostic (6.57e-2)" "prognostic unfavorable (1.53e-5)" "unprognostic (1.36e-1)" "unprognostic (5.13e-2)" "unprognostic (1.05e-2)" "unprognostic (3.68e-2)" CFL1 CFL ENSG00000172757 "Cofilin 1" P23528 11 65823022-65862026 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033687, CAB037077, HPA053761, HPA077782" Approved Supported "Plasma membrane" NA NA 290000000 "Cluster 29: Non-specific - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 14: Neurons - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 45: Non-specific - Mixed function" 12 "Plasma membrane" "CAB033687: AB_1121774, CAB037077: AB_1078547, HPA053761: AB_2682251, HPA077782: " "unprognostic (1.14e-1)" "unprognostic (2.37e-2)" "unprognostic (7.69e-3)" "unprognostic (4.32e-3)" "unprognostic (3.14e-2)" "unprognostic (2.09e-2)" "prognostic unfavorable (1.73e-5)" "unprognostic (1.59e-3)" "unprognostic (2.52e-1)" "unprognostic (5.88e-3)" "unprognostic (6.57e-3)" "unprognostic (2.09e-1)" "unprognostic (6.19e-3)" "unprognostic (1.72e-2)" "unprognostic (1.82e-1)" "unprognostic (1.49e-1)" "unprognostic (2.06e-1)" CFTR "ABC35, ABCC7, CF, CFTR/MRP, dJ760C5.1, MRP7, TNR-CFTR" ENSG00000001626 "CF transmembrane conductance regulator" P13569 7 117287120-117715971 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Isomerase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 48.4;intestine: 43.6;pancreas: 192.0" "Group enriched" "Detected in many" 4 "Ductal cells: 590.0;Late spermatids: 149.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.9;pancreatic cancer: 28.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 24.2;Gastric cancer: 9.6" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB001951, HPA021939, HPA079652" Enhanced NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 11: White matter - Signal transduction" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Non-specific - Mixed function" 94 "CAB001951: , HPA021939: AB_1846578, HPA079652: " "unprognostic (6.38e-3)" "unprognostic (9.55e-2)" "unprognostic (1.77e-2)" "unprognostic (1.44e-2)" "unprognostic (8.74e-2)" "unprognostic (8.57e-2)" "prognostic unfavorable (9.44e-4)" "unprognostic (3.20e-3)" "unprognostic (1.13e-1)" "unprognostic (8.89e-2)" "unprognostic (1.55e-2)" "unprognostic (2.14e-2)" "unprognostic (4.78e-3)" "unprognostic (1.24e-1)" "unprognostic (2.58e-1)" "unprognostic (9.08e-2)" "unprognostic (6.64e-2)" CHMP2A "BC-2, CHMP2, VPS2, VPS2A" ENSG00000130724 "Charged multivesicular body protein 2A" O43633 19 58551452-58555105 "Predicted intracellular proteins" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041153, HPA042031" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 230000 "Cluster 21: Neutrophils - Unknown function" "Cluster 23: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" 5 Cytosol "Nucleoplasm, Plasma membrane" "HPA041153: AB_10964358, HPA042031: AB_10961727" "unprognostic (1.80e-1)" "unprognostic (4.70e-2)" "unprognostic (7.29e-2)" "unprognostic (1.44e-3)" "unprognostic (6.60e-2)" "unprognostic (2.54e-1)" "unprognostic (3.86e-2)" "unprognostic (2.60e-1)" "unprognostic (1.01e-1)" "unprognostic (1.45e-2)" "unprognostic (2.69e-1)" "unprognostic (1.45e-1)" "unprognostic (2.98e-1)" "unprognostic (2.21e-1)" "unprognostic (3.09e-2)" "unprognostic (4.23e-2)" "unprognostic (2.71e-2)" CHMP2B "CHMP2.5, DKFZP564O123, VPS2B" ENSG00000083937 "Charged multivesicular body protein 2B" Q9UQN3 3 87227271-87255556 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035069, HPA052754" Uncertain Approved Cytosol NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 48: Stomach - Proteolysis" "Cluster 30: White matter - Myelination" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" 3 Cytosol "HPA035069: AB_10602798, HPA052754: AB_2681936" "unprognostic (7.83e-3)" "unprognostic (7.45e-2)" "unprognostic (2.01e-3)" "unprognostic (4.05e-2)" "unprognostic (1.51e-1)" "unprognostic (2.35e-1)" "unprognostic (1.02e-2)" "unprognostic (1.52e-2)" "unprognostic (9.78e-2)" "unprognostic (8.69e-2)" "prognostic unfavorable (2.11e-5)" "unprognostic (5.76e-2)" "prognostic favorable (1.74e-6)" "unprognostic (6.52e-2)" "unprognostic (2.29e-1)" "unprognostic (6.41e-3)" "unprognostic (1.21e-1)" CHMP3 "CGI-149, NEDF, VPS24" ENSG00000115561 "Charged multivesicular body protein 3" Q9Y3E7 2 86503430-86563479 "Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015673, HPA073383" Supported NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 30: Heart muscle - Heart development" "Cluster 14: Neurons - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 45: Non-specific - Mixed function" 4 "HPA015673: AB_1858761, HPA073383: AB_2732224" "unprognostic (2.49e-3)" "unprognostic (1.32e-1)" "unprognostic (7.29e-2)" "unprognostic (1.35e-2)" "unprognostic (2.13e-1)" "unprognostic (2.83e-2)" "prognostic unfavorable (3.92e-5)" "unprognostic (2.67e-1)" "unprognostic (6.16e-2)" "unprognostic (8.40e-2)" "prognostic unfavorable (7.39e-4)" "unprognostic (1.20e-1)" "prognostic favorable (5.32e-4)" "unprognostic (1.34e-1)" "unprognostic (8.85e-2)" "unprognostic (2.61e-1)" "unprognostic (1.64e-1)" CHMP4B "C20orf178, dJ553F4.4, Shax1, SNF7-2, VPS32B" ENSG00000101421 "Charged multivesicular body protein 4B" Q9H444 20 33811348-33854366 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction, Protein transport, Transport" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 489.3;Syncytiotrophoblasts: 470.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041401, HPA051751" Enhanced NA NA 53000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 45: Non-specific - Mixed function" 14 "HPA041401: AB_10965028, HPA051751: AB_2681591" "unprognostic (2.56e-2)" "unprognostic (6.12e-2)" "unprognostic (1.07e-1)" "unprognostic (9.04e-3)" "unprognostic (9.85e-2)" "unprognostic (8.52e-2)" "prognostic unfavorable (5.10e-4)" "unprognostic (1.49e-1)" "unprognostic (4.37e-2)" "unprognostic (1.24e-2)" "unprognostic (6.44e-3)" "unprognostic (1.31e-1)" "unprognostic (6.09e-2)" "unprognostic (2.31e-1)" "unprognostic (5.50e-2)" "unprognostic (1.20e-2)" "unprognostic (3.33e-2)" CHMP4C "MGC22825, Shax3, VPS32C" ENSG00000164695 "Charged multivesicular body protein 4C" Q96CF2 8 81732448-81759515 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 40.7" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 79.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "NK-cell: 1.9" "Lineage enriched" "Detected in single" 5 "NK-cells: 1.9" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA023763, HPA023799" Enhanced Approved "Microtubules,Cytokinetic bridge" Yes NA "Cluster 14: Non-specific - Unknown function" "Cluster 48: Stomach - Proteolysis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 40: Non-specific - Unknown function" "Cluster 45: Non-specific - Mixed function" 2 "Microtubules, Cytokinetic bridge" "HPA023763: , HPA023799: AB_1846670" "unprognostic (3.98e-2)" "unprognostic (6.75e-3)" "unprognostic (1.58e-1)" "unprognostic (5.19e-2)" "unprognostic (3.12e-2)" "unprognostic (2.45e-2)" "unprognostic (5.75e-2)" "prognostic unfavorable (9.33e-5)" "unprognostic (7.54e-2)" "unprognostic (8.08e-2)" "prognostic unfavorable (6.99e-5)" "unprognostic (1.99e-2)" "prognostic favorable (1.96e-6)" "unprognostic (3.29e-3)" "unprognostic (4.95e-1)" "unprognostic (2.67e-1)" "prognostic favorable (6.45e-4)" CHMP5 "C9orf83, CGI-34, HSPC177, SNF7DC2, Vps60" ENSG00000086065 "Charged multivesicular body protein 5" Q9NZZ3 9 33264879-33282070 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033874, HPA042883, HPA056437" Enhanced Supported Microtubules,Midbody,Cytosol Yes No 22000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 52: Kidney - Transmembrane transport" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 45: Non-specific - Mixed function" 5 "Microtubules, Cytosol" Midbody "CAB033874: AB_10608611, HPA042883: AB_2678212, HPA056437: AB_2683133" "unprognostic (1.10e-1)" "unprognostic (1.10e-1)" "unprognostic (9.08e-2)" "unprognostic (1.07e-1)" "unprognostic (2.32e-1)" "unprognostic (4.56e-2)" "unprognostic (3.87e-2)" "unprognostic (2.18e-2)" "unprognostic (4.71e-2)" "unprognostic (2.14e-3)" "unprognostic (7.94e-2)" "unprognostic (2.66e-1)" "prognostic favorable (2.87e-7)" "unprognostic (2.22e-1)" "unprognostic (9.59e-2)" "unprognostic (1.73e-1)" "unprognostic (7.31e-2)" CHST4 "HEC-GLCNAC-6-ST, LSST" ENSG00000140835 "Carbohydrate sulfotransferase 4" Q8NCG5 16 71525233-71538748 "Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Inflammatory response" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "gallbladder: 67.1" "Cell type enriched" "Detected in some" 27 "Cholangiocytes: 173.6" "Cancer enriched" "Detected in many" 6 "pancreatic cancer: 10.1" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 13.1;pancreatic cancer: 6.4" "Adipose visceral - Mesothelial cells, Liver - Cholangiocyte" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA021955 Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" "HPA021955: AB_1846723" "unprognostic (2.22e-3)" "unprognostic (1.41e-1)" "unprognostic (8.87e-2)" "unprognostic (3.35e-2)" "unprognostic (4.76e-3)" "unprognostic (6.86e-2)" "prognostic unfavorable (9.24e-4)" "unprognostic (1.26e-1)" "unprognostic (1.70e-1)" "unprognostic (1.15e-2)" "unprognostic (1.00e-1)" "unprognostic (2.27e-6)" "unprognostic (1.46e-2)" "unprognostic (1.08e-1)" "unprognostic (5.46e-2)" "unprognostic (1.73e-1)" CIB1 "CIB, KIP, SIP2-28" ENSG00000185043 "Calcium and integrin binding 1" Q99828 15 90229975-90234047 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Angiogenesis, Apoptosis, Cell adhesion, Cell cycle, Cell division, Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ciliated cells: 808.4;Late spermatids: 1386.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012991, HPA042413, HPA048825, HPA074310" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 8: Immune cells - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" 20 "Nucleoplasm, Plasma membrane" "CAB012991: AB_2533205, HPA042413: AB_2732498, HPA048825: AB_2680533, HPA074310: " "unprognostic (1.20e-1)" "unprognostic (1.59e-1)" "unprognostic (1.73e-2)" "prognostic favorable (2.26e-5)" "unprognostic (7.56e-2)" "unprognostic (5.51e-2)" "unprognostic (1.21e-2)" "unprognostic (8.29e-3)" "unprognostic (1.77e-1)" "unprognostic (4.09e-2)" "unprognostic (5.25e-3)" "unprognostic (2.44e-1)" "unprognostic (1.29e-3)" "unprognostic (1.85e-1)" "unprognostic (6.31e-2)" "unprognostic (1.39e-1)" "unprognostic (2.68e-2)" CLDN14 DFNB29 ENSG00000159261 "Claudin 14" O95500 21 36460621-36576569 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 26 "kidney: 13.4;liver: 38.6" "Cell type enhanced" "Detected in some" "Cholangiocytes: 3.8;Distal tubular cells: 9.2;Ductal cells: 12.0;Exocrine glandular cells: 4.6;Glandular and luminal cells: 4.7;Hepatocytes: 18.6" "Cancer enriched" "Detected in many" 6 "liver cancer: 7.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lymphoma: 7.9" "Liver - Hepatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA054707 Uncertain Vesicles NA NA "Cluster 1: Liver & Kidney - Metabolism" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 45: Non-specific - Mixed function" 4 Vesicles "HPA054707: " "unprognostic (1.14e-1)" "unprognostic (2.21e-1)" "unprognostic (3.74e-2)" "unprognostic (9.43e-2)" "unprognostic (8.20e-3)" "unprognostic (5.54e-2)" "prognostic favorable (1.53e-4)" "unprognostic (3.50e-4)" "unprognostic (2.28e-1)" "unprognostic (2.30e-2)" "unprognostic (2.12e-2)" "unprognostic (4.87e-1)" "unprognostic (7.44e-4)" "unprognostic (2.77e-2)" "unprognostic (7.65e-2)" "unprognostic (2.45e-2)" "unprognostic (9.71e-2)" CLDN18 SFTPJ ENSG00000066405 "Claudin 18" P56856 3 137998735-138033655 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 51 "lung: 244.4;stomach 1: 706.2" "Group enriched" "Detected in some" 32 "Alveolar cells type 1: 661.9;Alveolar cells type 2: 361.3;Gastric mucus-secreting cells: 1092.4" "Group enriched" "Detected in some" 11 "pancreatic cancer: 113.6;stomach cancer: 186.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 17.9;pancreatic cancer: 12.4" "Lung - Alveolar cells type 1, Stomach - Gastric mucous cells, Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "CAB013010, CAB013243, HPA018446" Enhanced Approved "Cell Junctions" NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 17: Choroid plexus - Cilium" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 45: Non-specific - Mixed function" 2 "Cell Junctions" "CAB013010: AB_2533382, CAB013243: AB_2533383, HPA018446: AB_2669866" "unprognostic (1.03e-1)" "unprognostic (1.49e-1)" "unprognostic (2.93e-1)" "unprognostic (1.04e-2)" "unprognostic (1.41e-1)" "unprognostic (8.51e-2)" "unprognostic (5.14e-4)" "unprognostic (2.00e-1)" "unprognostic (1.29e-1)" "unprognostic (2.60e-1)" "unprognostic (9.54e-2)" "unprognostic (1.38e-2)" "unprognostic (4.42e-5)" "unprognostic (1.66e-1)" "unprognostic (2.26e-1)" "unprognostic (8.26e-2)" "unprognostic (2.95e-1)" CLIC1 "CLCNL1, G6, NCC27, p64CLCP" ENSG00000213719 "Chloride intracellular channel 1" O00299 6 31730581-31739763 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 1604.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020825, CAB040557" Enhanced Supported Cytosol NA NA 22000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 12: Non-specific - Vasculature" "Cluster 28: Non-specific - Nuclear processes" "Cluster 45: Non-specific - Mixed function" 4 Cytosol "CAB020825: , CAB040557: " "unprognostic (7.26e-2)" "unprognostic (9.32e-2)" "unprognostic (2.78e-3)" "unprognostic (7.29e-2)" "unprognostic (6.93e-2)" "unprognostic (2.73e-2)" "prognostic unfavorable (8.90e-7)" "unprognostic (2.58e-2)" "unprognostic (8.51e-2)" "unprognostic (8.71e-3)" "unprognostic (1.19e-3)" "unprognostic (1.34e-1)" "prognostic unfavorable (8.11e-5)" "unprognostic (4.51e-2)" "unprognostic (2.89e-1)" "unprognostic (1.35e-2)" "unprognostic (7.31e-2)" CLTB Lcb ENSG00000175416 "Clathrin light chain B" P09497 5 176392501-176416539 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 798.8;Extravillous trophoblasts: 687.0;Suprabasal keratinocytes: 1123.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003692, HPA036458" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 21: Testis - Unknown function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 2 Vesicles "Plasma membrane, Cytosol" "CAB003692: AB_425372, HPA036458: AB_2675136" "unprognostic (1.09e-1)" "unprognostic (1.73e-1)" "unprognostic (4.51e-2)" "unprognostic (1.46e-1)" "unprognostic (1.34e-2)" "unprognostic (1.60e-1)" "unprognostic (3.54e-3)" "unprognostic (1.83e-2)" "unprognostic (1.74e-2)" "unprognostic (1.93e-1)" "unprognostic (7.42e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (7.89e-5)" "unprognostic (3.55e-1)" "unprognostic (7.50e-2)" "unprognostic (8.59e-2)" "unprognostic (1.60e-2)" COX17 ENSG00000138495 "Cytochrome c oxidase copper chaperone COX17" Q14061 3 119654513-119677454 "Cancer-related genes, Predicted intracellular proteins" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 882.7;Distal tubular cells: 814.5;Hepatocytes: 921.5;Proximal tubular cells: 824.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042226, HPA048158" Supported Supported Mitochondria NA NA 220000 "Cluster 32: Basophils - Transcription" "Cluster 35: Non-specific - Mitochondria" "Cluster 44: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 45: Non-specific - Mixed function" 4 Mitochondria "HPA042226: AB_2677911, HPA048158: AB_2680292" "unprognostic (1.98e-2)" "unprognostic (3.49e-2)" "unprognostic (1.96e-2)" "unprognostic (8.29e-2)" "unprognostic (2.88e-2)" "unprognostic (6.63e-3)" "unprognostic (3.49e-2)" "unprognostic (2.90e-1)" "unprognostic (1.36e-1)" "unprognostic (7.11e-3)" "unprognostic (2.12e-1)" "unprognostic (4.45e-2)" "unprognostic (1.33e-2)" "unprognostic (2.15e-2)" "unprognostic (1.65e-1)" "unprognostic (9.19e-2)" "unprognostic (2.64e-2)" CPA4 CPA3 ENSG00000128510 "Carboxypeptidase A4" Q9UI42 7 130293134-130324180 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 21.0;skin 1: 55.5" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 11.9;Basal respiratory cells: 23.5;Exocrine glandular cells: 48.8;Mesothelial cells: 9.1;Squamous epithelial cells: 11.5;Suprabasal keratinocytes: 19.9" "Cancer enhanced" "Detected in many" "cervical cancer: 10.0;head and neck cancer: 9.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 157.9" "Adipose visceral - Mesothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA021030 Approved "Nucleoplasm,Plasma membrane,Centriolar satellite" "Secreted in other tissues" Enzyme NA Yes 390000 "Cluster 13: Skin - Cornification" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Non-specific - Mixed function" "Nucleoplasm, Plasma membrane" "Centriolar satellite" "HPA021030: AB_1846010" "unprognostic (7.60e-3)" "unprognostic (4.00e-2)" "unprognostic (1.59e-3)" "unprognostic (3.63e-3)" "unprognostic (2.24e-2)" "unprognostic (2.91e-2)" "unprognostic (2.78e-2)" "unprognostic (4.36e-3)" "unprognostic (3.23e-1)" "unprognostic (5.79e-2)" "unprognostic (2.37e-3)" "unprognostic (6.49e-2)" "unprognostic (6.21e-10)" "unprognostic (2.39e-1)" "unprognostic (1.67e-1)" "unprognostic (7.56e-2)" "prognostic unfavorable (1.31e-4)" CRB3 MGC17303 ENSG00000130545 "Crumbs cell polarity complex component 3" Q9BUF7 19 6463777-6467221 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 53.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 167.0" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "choroid plexus: 14.1" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 9.2" "Group enriched" "Detected in many" 21 "B-cells: 3.1;T-cells: 9.2" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA013835 Enhanced Supported "Cell Junctions" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 48: Stomach - Proteolysis" "Cluster 5: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 2 "Cell Junctions" "HPA013835: AB_1847214" "unprognostic (3.25e-1)" "unprognostic (4.41e-2)" "unprognostic (9.69e-2)" "prognostic favorable (4.54e-4)" "unprognostic (1.24e-1)" "unprognostic (1.95e-2)" "unprognostic (2.81e-1)" "unprognostic (1.03e-2)" "unprognostic (1.86e-1)" "unprognostic (2.57e-2)" "unprognostic (4.98e-2)" "unprognostic (1.11e-1)" "prognostic favorable (0.00e+0)" "unprognostic (8.42e-3)" "unprognostic (1.96e-1)" "unprognostic (1.12e-2)" "prognostic favorable (8.06e-5)" CST6 ENSG00000175315 "Cystatin E/M" Q15828 11 66012008-66013505 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 22 "skin 1: 738.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 383.3;Ciliated cells: 227.1;Mesothelial cells: 127.7;Pancreatic endocrine cells: 329.4;Suprabasal keratinocytes: 99.2" "Group enriched" "Detected in many" 5 "thyroid cancer: 171.0;urothelial cancer: 43.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 203.3;Bladder cancer: 187.9;pancreatic cancer: 182.1" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB019316, HPA044963" Enhanced Approved "Plasma membrane,Cytosol" "Secreted in other tissues" "Enzyme inhibitor" NA NA 82000000 "Cluster 13: Skin - Cornification" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 1 "Plasma membrane" Cytosol "CAB019316: , HPA044963: AB_2679158" "unprognostic (3.01e-2)" "unprognostic (5.10e-2)" "unprognostic (1.14e-1)" "unprognostic (3.59e-2)" "unprognostic (5.00e-2)" "unprognostic (2.60e-1)" "unprognostic (1.65e-1)" "unprognostic (8.38e-2)" "unprognostic (5.02e-1)" "unprognostic (8.89e-3)" "unprognostic (1.29e-3)" "unprognostic (1.46e-1)" "unprognostic (1.74e-3)" "unprognostic (5.89e-3)" "unprognostic (1.83e-1)" "unprognostic (1.64e-2)" "unprognostic (2.59e-2)" CTDSP2 "OS4, PSR2, SCP2" ENSG00000175215 "CTD small phosphatase 2" O14595 12 57819927-57846729 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052607 Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 41: Basophils - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" 4 Nucleoplasm Mitochondria "HPA052607: AB_2681883" "unprognostic (7.09e-2)" "unprognostic (2.45e-1)" "unprognostic (1.84e-2)" "unprognostic (3.07e-2)" "unprognostic (4.39e-1)" "unprognostic (5.57e-2)" "unprognostic (1.05e-3)" "unprognostic (2.45e-2)" "unprognostic (1.04e-1)" "unprognostic (1.06e-2)" "unprognostic (1.12e-1)" "unprognostic (4.15e-1)" "unprognostic (7.38e-3)" "unprognostic (5.50e-2)" "unprognostic (6.50e-2)" "unprognostic (2.18e-1)" "unprognostic (3.11e-1)" CTNNA1 CAP102 ENSG00000044115 "Catenin alpha 1" P35221 5 138610967-138935034 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 411.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021089, HPA046119, HPA063535" Supported Supported "Plasma membrane,Cell Junctions" NA NA 57000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 11: White matter - Signal transduction" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 45: Non-specific - Mixed function" 10 "Plasma membrane, Cell Junctions" "CAB021089: AB_10123543, HPA046119: AB_2679547, HPA063535: AB_2685033" "unprognostic (2.25e-3)" "unprognostic (3.32e-2)" "unprognostic (2.82e-3)" "unprognostic (1.80e-1)" "unprognostic (8.40e-2)" "unprognostic (2.35e-1)" "unprognostic (1.66e-3)" "unprognostic (4.83e-2)" "unprognostic (2.28e-1)" "unprognostic (2.48e-1)" "prognostic unfavorable (8.02e-4)" "unprognostic (6.18e-2)" "prognostic favorable (7.34e-7)" "unprognostic (1.54e-1)" "unprognostic (2.31e-1)" "unprognostic (7.62e-2)" "unprognostic (1.04e-1)" CTRB2 ENSG00000168928 "Chymotrypsinogen B2" Q6GPI1 16 75204103-75207161 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 3540 "pancreas: 95538.0" "Cell type enriched" "Detected in some" 9 "Exocrine glandular cells: 29617.7" "Cancer enriched" "Detected in single" 1696 "pancreatic cancer: 540.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" Enzyme NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" "unprognostic (9.41e-4)" "unprognostic (2.20e-1)" "unprognostic (1.28e-2)" "unprognostic (2.10e-1)" "unprognostic (2.92e-2)" "unprognostic (2.77e-1)" "unprognostic (5.95e-2)" "unprognostic (9.56e-2)" "unprognostic (3.54e-3)" "unprognostic (7.06e-2)" "unprognostic (2.17e-1)" "unprognostic (7.57e-2)" CTSE ENSG00000196188 "Cathepsin E" P14091 1 206008535-206023909 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "stomach 1: 1138.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 553.6;Alveolar cells type 2: 190.6;Exocrine glandular cells: 130.0;Gastric mucus-secreting cells: 626.1;Paneth cells: 256.7" "Cancer enhanced" "Detected in many" "pancreatic cancer: 297.4;stomach cancer: 200.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "colorectal cancer: 28.4;Esophageal cancer: 48.8;Gastric cancer: 110.7;pancreatic cancer: 35.3" "Colon - Colon enterocytes, Stomach - Gastric mucous cells" "Not detected" "Not detected" "HPA012674, HPA012940, CAB032687" Enhanced Approved Vesicles "Intracellular and membrane" Enzyme NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 9: Non-specific - Receptor signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Non-specific - Mixed function" Vesicles "CAB032687: AB_637901, HPA012674: , HPA012940: AB_2668773" "unprognostic (1.17e-2)" "unprognostic (2.45e-1)" "unprognostic (1.31e-2)" "unprognostic (2.72e-2)" "unprognostic (1.35e-2)" "unprognostic (2.52e-3)" "unprognostic (1.45e-1)" "unprognostic (3.29e-2)" "unprognostic (2.87e-2)" "unprognostic (1.20e-2)" "unprognostic (1.39e-1)" "unprognostic (6.37e-3)" "unprognostic (1.42e-1)" "unprognostic (5.45e-2)" "unprognostic (2.61e-2)" "prognostic favorable (5.26e-5)" CTTN EMS1 ENSG00000085733 Cortactin Q14247 11 70398404-70436584 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Endocytosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.2;neutrophil: 2.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.1" "Low cancer specificity" "Detected in all" "Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011235, HPA057242" Supported Supported "Golgi apparatus,Vesicles,Plasma membrane,Cytosol" NA NA 11000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 66: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 45: Non-specific - Mixed function" 5 "Plasma membrane, Cytosol" "Golgi apparatus, Vesicles" "CAB011235: , HPA057242: AB_2683379" "unprognostic (6.34e-2)" "unprognostic (2.65e-2)" "unprognostic (2.05e-1)" "unprognostic (3.13e-2)" "unprognostic (5.81e-2)" "prognostic unfavorable (2.19e-6)" "prognostic unfavorable (4.45e-4)" "unprognostic (6.10e-2)" "unprognostic (2.39e-1)" "unprognostic (1.10e-1)" "unprognostic (1.25e-3)" "unprognostic (1.20e-1)" "unprognostic (1.50e-2)" "unprognostic (6.97e-2)" "unprognostic (2.79e-1)" "unprognostic (3.72e-3)" "unprognostic (1.94e-1)" CUZD1 "ERG-1, UO-44" ENSG00000138161 "CUB and zona pellucida like domains 1" Q86UP6 10 122832158-122846175 "Predicted membrane proteins" "Cell adhesion, Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1623 "pancreas: 2338.0" "Cell type enriched" "Detected in some" 42 "Exocrine glandular cells: 71.9" "Cancer enriched" "Detected in some" 54 "pancreatic cancer: 32.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA068479, HPA068660, HPA074117" Enhanced NA No "Cluster 15: Pancreas - Proteolysis" "Cluster 13: Non-specific - Mixed function" "Cluster 45: Non-specific - Mixed function" "HPA068479: AB_2685995, HPA068660: AB_2686015, HPA074117: AB_2686663" "unprognostic (4.68e-2)" "unprognostic (3.48e-2)" "unprognostic (1.53e-2)" "unprognostic (1.52e-5)" "unprognostic (8.08e-2)" "unprognostic (5.20e-3)" "unprognostic (1.16e-4)" "unprognostic (4.19e-2)" "unprognostic (3.03e-2)" "unprognostic (5.15e-2)" "unprognostic (8.46e-2)" "unprognostic (6.64e-3)" "unprognostic (2.75e-3)" "unprognostic (4.48e-1)" "unprognostic (1.38e-1)" "unprognostic (1.56e-1)" "unprognostic (4.83e-4)" CYSTM1 "C5orf32, ORF1-FL49" ENSG00000120306 "Cysteine rich transmembrane module containing 1" Q9H1C7 5 140175156-140282052 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "stomach 1: 1282.0" "Cell type enhanced" "Detected in all" "Distal enterocytes: 1271.0;Distal tubular cells: 2259.0;Gastric mucus-secreting cells: 2148.3;Late spermatids: 1672.2;Proximal tubular cells: 1230.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 7 "neutrophil: 427.5" "Lineage enriched" "Detected in all" 7 "granulocytes: 427.5" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Stomach - Gastric mucous cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050930 Enhanced NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 68: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Non-specific - Mixed function" 2 "HPA050930: AB_2681278" "unprognostic (7.39e-2)" "unprognostic (3.68e-2)" "unprognostic (4.46e-2)" "prognostic favorable (1.31e-4)" "unprognostic (5.38e-2)" "unprognostic (1.63e-3)" "prognostic unfavorable (1.71e-4)" "unprognostic (2.26e-1)" "unprognostic (1.12e-1)" "unprognostic (2.73e-1)" "unprognostic (2.53e-1)" "unprognostic (2.24e-1)" "prognostic favorable (9.69e-5)" "unprognostic (7.63e-2)" "unprognostic (2.23e-1)" "unprognostic (4.67e-2)" "unprognostic (1.14e-2)" CYTH2 "ARNO, CTS18.1, cytohesin-2, PSCD2, PSCD2L, Sec7p-L, Sec7p-like" ENSG00000105443 "Cytohesin 2" Q99418 19 48469208-48482314 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 317.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB014872, HPA060662" Uncertain Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 39: Retina & Testis - Cilium" "Cluster 6: Non-specific - Immune response" "Cluster 56: Non-specific - Sensory perception" "Cluster 45: Non-specific - Mixed function" 6 Cytosol "Golgi apparatus, Plasma membrane" "CAB014872: , HPA060662: AB_2732652" "unprognostic (2.28e-1)" "unprognostic (1.27e-1)" "unprognostic (7.60e-3)" "unprognostic (1.72e-1)" "unprognostic (4.97e-2)" "unprognostic (4.10e-2)" "prognostic unfavorable (1.19e-4)" "unprognostic (1.66e-1)" "unprognostic (2.83e-2)" "unprognostic (3.70e-1)" "unprognostic (1.85e-1)" "unprognostic (2.33e-2)" "unprognostic (9.19e-2)" "unprognostic (3.14e-1)" "unprognostic (1.22e-1)" "unprognostic (1.24e-1)" "prognostic favorable (3.21e-4)" DAPK3 "ZIP, ZIPK" ENSG00000167657 "Death associated protein kinase 3" O43293 19 3958453-3971123 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation, Translation regulation" "Activator, Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028569 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 53: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" 2 Cytosol Nucleoplasm "HPA028569: AB_10794319" "unprognostic (5.72e-2)" "unprognostic (3.28e-2)" "unprognostic (3.34e-3)" "prognostic favorable (2.01e-5)" "unprognostic (1.83e-1)" "unprognostic (2.37e-1)" "unprognostic (7.72e-3)" "unprognostic (2.16e-1)" "unprognostic (2.46e-2)" "unprognostic (4.95e-2)" "unprognostic (1.84e-3)" "unprognostic (7.64e-2)" "prognostic unfavorable (6.49e-4)" "unprognostic (9.92e-2)" "unprognostic (1.41e-1)" "unprognostic (5.48e-2)" "unprognostic (2.14e-1)" DBN1 D0S117E ENSG00000113758 "Drebrin 1" Q16643 5 177456608-177474401 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Actin-binding, Developmental protein" "Alzheimer disease, Amyloidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 76.5;Fibroblasts: 67.3;Lymphatic endothelial cells: 68.6;Pancreatic endocrine cells: 69.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "dendritic cells: 5.3;granulocytes: 9.2;T-cells: 13.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Liver - Vascular Endothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051452, HPA056940" Enhanced Supported Supported "Plasma membrane,Actin filaments" NA NA 2000000 "Cluster 1: T-cells - Unknown function" "Cluster 64: Neuronal - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 45: Non-specific - Mixed function" 7 "Plasma membrane, Actin filaments" "HPA051452: AB_2681489, HPA056940: AB_2683279" "unprognostic (3.81e-2)" "unprognostic (6.60e-3)" "unprognostic (2.88e-2)" "unprognostic (7.57e-3)" "unprognostic (9.32e-2)" "unprognostic (5.68e-2)" "unprognostic (2.01e-3)" "unprognostic (4.29e-2)" "unprognostic (1.73e-2)" "unprognostic (7.92e-2)" "unprognostic (2.94e-2)" "unprognostic (3.64e-1)" "prognostic favorable (8.28e-4)" "unprognostic (1.53e-1)" "unprognostic (4.56e-2)" "unprognostic (1.05e-1)" "unprognostic (1.76e-3)" DBNDD1 "FLJ12582, MGC3101" ENSG00000003249 "Dysbindin domain containing 1" Q9H9R9 16 90004871-90019890 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 89.2;skeletal muscle: 46.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 16.1;Cholangiocytes: 21.0;Exocrine glandular cells: 17.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "naive B-cell: 12.9" "Lineage enriched" "Detected in many" 4 "B-cells: 12.9" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043018 Uncertain Approved "Nuclear speckles,Cytosol" No No "Cluster 34: B-cells - Unknown function" "Cluster 61: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 45: Non-specific - Mixed function" "Nuclear speckles" Cytosol "HPA043018: AB_10794921" "unprognostic (1.07e-1)" "unprognostic (8.40e-2)" "unprognostic (8.70e-2)" "unprognostic (1.73e-1)" "unprognostic (1.86e-2)" "unprognostic (4.18e-2)" "unprognostic (1.51e-1)" "unprognostic (1.70e-1)" "unprognostic (6.07e-2)" "unprognostic (9.52e-2)" "unprognostic (1.54e-1)" "unprognostic (2.86e-2)" "prognostic favorable (2.75e-7)" "unprognostic (1.03e-1)" "unprognostic (5.67e-1)" "unprognostic (2.44e-2)" "unprognostic (2.00e-2)" DCTD ENSG00000129187 "DCMP deaminase" P32321 4 182890060-182917936 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Nucleotide biosynthesis" "Allosteric enzyme, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035894 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 22: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 45: Non-specific - Mixed function" 8 "Nucleoplasm, Cytosol" "HPA035894: AB_10673488" "unprognostic (1.26e-1)" "unprognostic (9.80e-3)" "unprognostic (3.15e-2)" "unprognostic (3.78e-3)" "unprognostic (3.13e-3)" "unprognostic (2.20e-2)" "unprognostic (2.01e-2)" "unprognostic (4.59e-3)" "unprognostic (2.62e-2)" "unprognostic (1.80e-1)" "unprognostic (1.40e-2)" "unprognostic (1.20e-1)" "prognostic favorable (1.81e-4)" "unprognostic (1.35e-1)" "unprognostic (1.59e-1)" "unprognostic (3.89e-2)" "unprognostic (1.12e-1)" DCTN2 "DCTN-50, RBP50" ENSG00000175203 "Dynactin subunit 2" Q13561 12 57529633-57547224 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039715, HPA040040" Enhanced Supported Centrosome,Cytosol NA NA 630000 "Cluster 29: Non-specific - Unknown function" "Cluster 79: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" 35 Centrosome Cytosol "HPA039715: AB_10795154, HPA040040: AB_10794870" "unprognostic (1.70e-2)" "unprognostic (1.82e-1)" "unprognostic (1.54e-1)" "unprognostic (6.88e-2)" "unprognostic (1.49e-1)" "unprognostic (1.85e-1)" "prognostic unfavorable (1.38e-7)" "unprognostic (1.14e-1)" "unprognostic (1.60e-1)" "unprognostic (1.71e-1)" "unprognostic (4.26e-2)" "unprognostic (1.35e-1)" "unprognostic (1.08e-2)" "unprognostic (9.50e-3)" "unprognostic (2.09e-1)" "unprognostic (1.52e-3)" "unprognostic (3.41e-3)" DDX19B "DBP5, DDX19" ENSG00000157349 "DEAD-box helicase 19B" Q9UMR2 16 70289663-70335305 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 190.0;Spermatocytes: 85.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037229, CAB037284, HPA046380, HPA066668" Approved Uncertain Nucleoplasm NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 21: Testis - Unknown function" "Cluster 2: Neurons - Nucleosome" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 45: Non-specific - Mixed function" 4 Nucleoplasm "CAB037229: AB_1840791, CAB037284: AB_1840792, HPA046380: AB_2679645, HPA066668: " "unprognostic (2.91e-2)" "unprognostic (5.37e-2)" "unprognostic (6.48e-2)" "unprognostic (3.55e-2)" "unprognostic (3.98e-2)" "unprognostic (4.05e-2)" "unprognostic (2.93e-2)" "unprognostic (1.98e-2)" "unprognostic (1.40e-1)" "unprognostic (1.05e-1)" "unprognostic (6.33e-2)" "unprognostic (4.07e-1)" "unprognostic (7.95e-2)" "unprognostic (2.19e-1)" "unprognostic (3.50e-1)" "unprognostic (1.04e-1)" "unprognostic (6.32e-2)" DEF8 FLJ20186 ENSG00000140995 "Differentially expressed in FDCP 8 homolog" Q6ZN54 16 89948697-89968060 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041745, HPA049434" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 65: Cerebellum - Nervous system development" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 45: Non-specific - Mixed function" "Nucleoplasm, Cytosol" "HPA041745: AB_2677650, HPA049434: " "unprognostic (4.99e-2)" "unprognostic (1.01e-1)" "unprognostic (9.41e-3)" "unprognostic (1.24e-1)" "unprognostic (1.08e-1)" "unprognostic (8.24e-2)" "unprognostic (1.91e-3)" "unprognostic (9.96e-2)" "unprognostic (2.74e-1)" "unprognostic (1.39e-2)" "prognostic favorable (1.35e-7)" "unprognostic (1.39e-2)" "prognostic favorable (1.95e-8)" "unprognostic (9.05e-2)" "unprognostic (1.40e-1)" "unprognostic (2.32e-2)" "unprognostic (2.09e-1)" DEFB103B ENSG00000177243 "Defensin beta 103B" P81534 8 7428888-7430348 "Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "cervix: 1.3" "Cell type enhanced" "Detected in single" "Suprabasal keratinocytes: 3.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" Defense NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 9 DEFB4A "DEFB-2, DEFB102, DEFB2, DEFB4, HBD-2, SAP1" ENSG00000171711 "Defensin beta 4A" O15263 8 7894677-7896716 "Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "esophagus: 120.7" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 22.4;Basal respiratory cells: 79.4;Exocrine glandular cells: 16.8;Ionocytes: 22.5;Pancreatic endocrine cells: 22.1" "Group enriched" "Detected in many" 6 "head and neck cancer: 32.2;melanoma: 9.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "head and neck cancer: 3.7;Uterine cancer: 8.1" "Secreted in other tissues" Defense NA NA "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" "unprognostic (6.96e-2)" "unprognostic (1.17e-2)" "unprognostic (2.72e-2)" "unprognostic (4.37e-1)" "unprognostic (1.08e-1)" "unprognostic (1.50e-1)" "unprognostic (2.75e-1)" DEFB4B DEFB4P ENSG00000177257 "Defensin beta 4B" O15263 8 7414855-7416863 "Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 11.6;lymphoid tissue: 3.3" "Cell type enhanced" "Detected in single" "Alveolar cells type 2: 1.6" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "head and neck cancer: 1.3" "Secreted in other tissues" Defense NA NA "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" "unprognostic (1.35e-1)" DHRSX "DHRS5X, DHRS5Y, DHRSXY, DHRSY, SDR46C1, SDR7C6" ENSG00000169084 "Dehydrogenase/reductase X-linked" Q8N5I4 X 2219506-2502805 "Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 106.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "HPA003035, HPA075955" Approved Uncertain "Mitotic spindle,Cytosol" "Secreted to blood" Enzyme Yes NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 68: Non-specific - Protein processing" "Cluster 46: Brainstem - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 45: Non-specific - Mixed function" 14 Cytosol "Mitotic spindle" "HPA003035: AB_1080631, HPA075955: " "unprognostic (7.77e-2)" "unprognostic (1.06e-1)" "unprognostic (3.95e-2)" "unprognostic (4.65e-3)" "unprognostic (8.87e-2)" "unprognostic (1.78e-1)" "unprognostic (1.29e-1)" "unprognostic (4.59e-3)" "unprognostic (1.08e-1)" "unprognostic (1.21e-1)" "unprognostic (1.08e-2)" "unprognostic (1.17e-1)" "unprognostic (1.10e-1)" "unprognostic (2.66e-1)" "unprognostic (1.57e-1)" "unprognostic (2.11e-1)" "unprognostic (3.69e-2)" DIAPH1 "DFNA1, hDIA1, LFHL1, mDia1" ENSG00000131504 "Diaphanous related formin 1" O60610 5 141515016-141619055 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Hearing Actin-binding "Cancer-related genes, Deafness, Disease variant, Epilepsy, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 165.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004916, HPA076913" Approved Uncertain "Plasma membrane,Cytosol" NA NA 2000000 "Cluster 25: Non-specific - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 45: Non-specific - Mixed function" 5 "Plasma membrane, Cytosol" "HPA004916: AB_1847668, HPA076913: " "unprognostic (6.79e-2)" "unprognostic (2.99e-1)" "unprognostic (2.12e-3)" "unprognostic (3.73e-2)" "unprognostic (4.18e-2)" "unprognostic (1.54e-1)" "unprognostic (2.08e-1)" "unprognostic (4.54e-3)" "unprognostic (2.03e-1)" "unprognostic (1.27e-2)" "prognostic unfavorable (7.81e-5)" "unprognostic (2.88e-3)" "prognostic favorable (1.29e-5)" "unprognostic (1.64e-2)" "unprognostic (1.84e-2)" "unprognostic (7.00e-2)" "unprognostic (1.65e-1)" DKK4 ENSG00000104371 "Dickkopf WNT signaling pathway inhibitor 4" Q9UBT3 8 42374063-42377229 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 4.8;intestine: 2.3" "Cell type enhanced" "Detected in some" "dendritic cells: 1.6;Early spermatids: 2.6;Gastric mucus-secreting cells: 1.8;Spermatocytes: 1.6;Suprabasal keratinocytes: 1.9" "Cancer enriched" "Detected in many" 20 "endometrial cancer: 174.4" "Region enhanced" "Detected in many" "cerebellum: 8.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 28 "breast cancer: 169.4" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA052916 Uncertain "Secreted in other tissues" "Developmental protein" NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 35: Non-specific - DNA binding" "Cluster 70: DU4475 - Unknown function" "Cluster 45: Non-specific - Mixed function" 4 "HPA052916: AB_2681987" "unprognostic (1.64e-1)" "unprognostic (5.84e-2)" "unprognostic (1.97e-1)" "unprognostic (5.37e-3)" "unprognostic (3.23e-1)" "unprognostic (2.91e-2)" "unprognostic (2.13e-2)" "unprognostic (1.99e-1)" "unprognostic (6.80e-2)" "unprognostic (2.71e-2)" "unprognostic (1.63e-2)" "unprognostic (6.73e-2)" "unprognostic (1.48e-2)" "unprognostic (3.53e-1)" "unprognostic (8.11e-2)" DLG3 "KIAA1232, MRX90, NE-Dlg, NEDLG, PPP1R82, SAP-102, SAP102" ENSG00000082458 "Discs large MAGUK scaffold protein 3" Q92796 X 70444835-70505490 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001733, HPA078130" Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 68: Non-specific - Protein processing" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 45: Non-specific - Mixed function" 5 "Nucleoplasm, Nucleoli" "HPA001733: AB_1078675, HPA078130: AB_2686879" "prognostic unfavorable (1.69e-4)" "unprognostic (1.87e-3)" "unprognostic (1.37e-1)" "unprognostic (2.77e-1)" "unprognostic (4.65e-2)" "unprognostic (3.44e-2)" "unprognostic (3.64e-1)" "unprognostic (1.20e-2)" "unprognostic (7.79e-2)" "unprognostic (7.92e-2)" "unprognostic (1.26e-1)" "unprognostic (5.98e-2)" "prognostic favorable (1.72e-10)" "unprognostic (3.36e-2)" "unprognostic (5.45e-2)" "unprognostic (1.51e-2)" "unprognostic (1.97e-3)" DSG2 CDHF5 ENSG00000046604 "Desmoglein 2" Q14126 18 31498177-31549008 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 152.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 281.5" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 10 "choroid plexus: 63.2" "Immune cell enriched" "Detected in single" 12 "basophil: 8.7" "Lineage enriched" "Detected in single" 12 "granulocytes: 8.7" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Skeletal muscle - Endothelial cells, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA004896, CAB025122" Enhanced Supported "Cell Junctions" NA NA 140000000 "Cluster 41: Basophils - Unknown function" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 36: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" "Cell Junctions" "CAB025122: , HPA004896: AB_1078643" "unprognostic (1.56e-3)" "prognostic unfavorable (8.22e-4)" "prognostic favorable (7.81e-4)" "unprognostic (8.77e-3)" "unprognostic (3.53e-4)" "prognostic unfavorable (5.63e-4)" "unprognostic (2.86e-3)" "prognostic unfavorable (2.43e-4)" "unprognostic (5.21e-2)" "unprognostic (1.49e-1)" "prognostic unfavorable (4.94e-5)" "unprognostic (3.40e-1)" "prognostic favorable (3.14e-10)" "unprognostic (1.76e-1)" "unprognostic (1.51e-1)" "unprognostic (3.72e-1)" "unprognostic (8.57e-3)" DTD1 "bA379J5.3, bA555E18.1, C20orf88, DUEB, HARS2, MGC119131, MGC41905, pqn-68" ENSG00000125821 "D-aminoacyl-tRNA deacylase 1" Q8TEA8 20 18587942-18766644 "Enzymes, Predicted intracellular proteins" "DNA replication" "DNA-binding, Hydrolase, RNA-binding, tRNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040981 Uncertain Uncertain Nucleoli,Cytosol NA NA 350000 "Cluster 15: NK-cells - Unknown function" "Cluster 34: Non-specific - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 62: Non-specific - Plasma proteins" "Cluster 45: Non-specific - Mixed function" "Nucleoli, Cytosol" "HPA040981: AB_10673268" "unprognostic (3.32e-1)" "unprognostic (1.05e-1)" "unprognostic (1.82e-1)" "unprognostic (5.94e-2)" "unprognostic (1.83e-1)" "unprognostic (2.90e-1)" "unprognostic (1.27e-3)" "unprognostic (9.67e-2)" "unprognostic (1.72e-1)" "unprognostic (1.81e-1)" "unprognostic (6.84e-2)" "unprognostic (1.32e-1)" "unprognostic (9.09e-3)" "unprognostic (2.42e-1)" "unprognostic (8.44e-2)" "unprognostic (2.59e-2)" "unprognostic (8.53e-2)" DUOX2 "LNOX2, P138-TOX, P138(TOX), THOX2" ENSG00000140279 "Dual oxidase 2" Q9NRD8 15 45092650-45114172 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Hydrogen peroxide, Thyroid hormones biosynthesis" "Oxidoreductase, Peroxidase" "Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 280.6;thyroid gland: 73.4;urinary bladder: 89.6" "Group enriched" "Detected in many" 4 "Ductal cells: 271.7;Exocrine glandular cells: 350.5;Gastric mucus-secreting cells: 90.8" "Cancer enhanced" "Detected in many" "thyroid cancer: 60.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 1.9;Esophageal cancer: 2.2;head and neck cancer: 3.4" "Prostate - Urothelial cells, Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Region enhanced" "Detected in single" "basal ganglia: 1.2" "Not detected" "Not detected" NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 1 "unprognostic (3.19e-1)" "unprognostic (7.51e-2)" "unprognostic (3.77e-2)" "unprognostic (5.99e-2)" "unprognostic (1.09e-1)" "unprognostic (1.40e-2)" "unprognostic (7.93e-2)" "unprognostic (3.32e-1)" "unprognostic (1.42e-1)" "unprognostic (4.49e-2)" "unprognostic (9.59e-3)" "unprognostic (7.11e-2)" "unprognostic (5.32e-5)" "unprognostic (1.71e-1)" "unprognostic (1.62e-2)" "unprognostic (4.12e-2)" "unprognostic (1.63e-2)" DUOXA2 ENSG00000140274 "Dual oxidase maturation factor 2" Q1HG44 15 45114326-45118421 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Protein transport, Transport" "Congenital hypothyroidism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 61.7;urinary bladder: 40.4" "Group enriched" "Detected in some" 7 "Ductal cells: 935.0;Exocrine glandular cells: 806.4" "Cancer enhanced" "Detected in many" "pancreatic cancer: 27.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA063548 Enhanced NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Non-specific - Mixed function" 1 "HPA063548: AB_2685037" "unprognostic (1.87e-1)" "unprognostic (9.88e-2)" "unprognostic (7.37e-2)" "unprognostic (6.45e-2)" "unprognostic (1.72e-1)" "unprognostic (2.00e-3)" "unprognostic (6.73e-2)" "unprognostic (2.03e-1)" "unprognostic (2.10e-1)" "unprognostic (3.15e-2)" "unprognostic (1.26e-2)" "unprognostic (1.17e-1)" "unprognostic (3.67e-4)" "unprognostic (9.75e-2)" "unprognostic (3.11e-1)" "unprognostic (1.37e-1)" "unprognostic (5.54e-2)" EFHD2 MGC4342 ENSG00000142634 "EF-hand domain family member D2" Q96C19 1 15409888-15430339 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 444.7;NK-cells: 481.5;Proximal enterocytes: 290.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 133.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Macrophages, Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048961 Enhanced Approved Cytosol No No 220000 "Cluster 7: Non-specific - Innate immune response" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 24: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" Cytosol "HPA048961: AB_2680572" "unprognostic (1.37e-3)" "unprognostic (3.69e-1)" "unprognostic (7.83e-2)" "unprognostic (4.44e-2)" "unprognostic (2.35e-1)" "unprognostic (3.82e-2)" "unprognostic (4.59e-2)" "prognostic unfavorable (5.57e-4)" "unprognostic (9.11e-2)" "unprognostic (9.61e-2)" "unprognostic (1.64e-1)" "unprognostic (1.71e-1)" "prognostic unfavorable (6.31e-9)" "unprognostic (2.71e-2)" "unprognostic (9.71e-2)" "prognostic favorable (2.70e-4)" "prognostic favorable (3.60e-5)" EIF4G2 "DAP5, NAT1, p97" ENSG00000110321 "Eukaryotic translation initiation factor 4 gamma 2" P78344 11 10797050-10808940 "Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis, Translation regulation" "Initiation factor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 1118.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005163, HPA006773, HPA016965" Approved Enhanced Cytosol NA NA 48000 "Cluster 40: Monocytes - Innate immune response" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 45: Non-specific - Mixed function" 5 Cytosol "CAB005163: AB_638994, HPA006773: AB_1848099, HPA016965: AB_1848100" "unprognostic (1.10e-2)" "unprognostic (1.57e-1)" "unprognostic (1.15e-1)" "unprognostic (1.34e-1)" "unprognostic (9.92e-2)" "unprognostic (2.52e-1)" "prognostic unfavorable (6.18e-5)" "unprognostic (1.25e-1)" "unprognostic (7.84e-3)" "unprognostic (5.42e-2)" "unprognostic (7.07e-2)" "unprognostic (2.63e-1)" "prognostic favorable (1.67e-4)" "unprognostic (1.02e-2)" "unprognostic (2.08e-1)" "unprognostic (6.16e-2)" "unprognostic (2.74e-1)" EIF6 "b(2)gcn, EIF3A, ITGB4BP, p27BBP" ENSG00000242372 "Eukaryotic translation initiation factor 6" P56537 20 35278907-35284985 "Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis, Ribosome biogenesis" "Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 532.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040873 Enhanced Supported Nucleoplasm NA NA 260000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 21: Non-specific - Metabolism" "Cluster 62: Non-specific - Plasma proteins" "Cluster 45: Non-specific - Mixed function" 5 Nucleoplasm "HPA040873: AB_2677182" "unprognostic (9.00e-2)" "unprognostic (2.65e-1)" "unprognostic (2.06e-1)" "unprognostic (1.38e-1)" "unprognostic (1.75e-1)" "unprognostic (2.24e-1)" "prognostic unfavorable (7.25e-5)" "unprognostic (9.94e-3)" "unprognostic (4.97e-2)" "unprognostic (1.14e-1)" "unprognostic (4.55e-3)" "unprognostic (2.63e-1)" "unprognostic (3.51e-2)" "unprognostic (1.53e-1)" "unprognostic (2.17e-1)" "unprognostic (9.18e-2)" "unprognostic (8.15e-2)" EMC4 "FLJ90746, MGC24415, PIG17, TMEM85" ENSG00000128463 "ER membrane protein complex subunit 4" Q5J8M3 15 34225013-34230156 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053440 Approved NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 27: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 45: Non-specific - Mixed function" 1 "HPA053440: AB_2682151" "unprognostic (8.99e-2)" "unprognostic (1.59e-1)" "unprognostic (7.68e-2)" "unprognostic (3.29e-2)" "unprognostic (9.23e-2)" "unprognostic (1.29e-3)" "unprognostic (3.25e-1)" "unprognostic (3.61e-2)" "unprognostic (1.65e-1)" "unprognostic (1.78e-3)" "unprognostic (1.33e-1)" "unprognostic (2.20e-2)" "unprognostic (2.52e-1)" "unprognostic (5.42e-2)" "unprognostic (4.20e-2)" "unprognostic (2.96e-1)" "unprognostic (1.97e-2)" ENSG00000267140 ENSG00000267140 "Novel protein" 18 35443871-35497940 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 4.7" "Cell type enhanced" "Detected in some" "granulocytes: 1.6;Melanocytes: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 45: Non-specific - Mixed function" "unprognostic (6.67e-3)" "unprognostic (5.32e-2)" "unprognostic (2.01e-1)" "unprognostic (3.51e-2)" "unprognostic (1.48e-2)" "unprognostic (2.24e-2)" "unprognostic (1.60e-1)" "unprognostic (7.77e-2)" "unprognostic (4.11e-2)" "unprognostic (1.04e-1)" "unprognostic (2.61e-1)" ENSG00000277400 ENSG00000277400 Q8WZ33 Unmapped 53590-115018 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Ductal cells: 3.9;Exocrine glandular cells: 2.3;Pancreatic endocrine cells: 3.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Intracellular and membrane" Transcription NA NA "Cluster 6: Non-specific - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 45: Non-specific - Mixed function" ENSG00000284969 ENSG00000284969 "Novel protein" 11 33698261-33722467 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 2.9;Ductal cells: 6.8;Endothelial cells: 3.6;Exocrine glandular cells: 7.0;Pancreatic endocrine cells: 5.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" HPA026494 Uncertain Uncertain "Golgi apparatus,Vesicles" NA NA "Cluster 44: Non-specific - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 45: Non-specific - Mixed function" "Golgi apparatus, Vesicles" "HPA026494: AB_1846321" ENSG00000285585 ENSG00000285585 "Novel protein" 3 119703076-119807570 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Distal enterocytes: 1.1;Proximal enterocytes: 2.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA074084 Uncertain NA NA "Cluster 20: Myeloma - Immune response" "Cluster 45: Non-specific - Mixed function" "HPA074084: " ERICH5 "C8orf47, FLJ39553" ENSG00000177459 "Glutamate rich 5" Q6P6B1 8 98064522-98093610 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 33.1" "Cell type enhanced" "Detected in many" "Cholangiocytes: 106.8;Ciliated cells: 41.2;Ductal cells: 55.4;Proximal tubular cells: 25.2" "Cancer enhanced" "Detected in many" "liver cancer: 23.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "myeloid DC: 2.2" "Lineage enriched" "Detected in single" 11 "dendritic cells: 2.2" "Cancer enhanced" "Detected in many" "liver cancer: 10.6" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells" "Not detected" "Not detected" "HPA025070, HPA025293, HPA027233" Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 15: Pancreas - Proteolysis" "Cluster 1: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 45: Non-specific - Mixed function" 2 "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA025070: AB_1845778, HPA025293: AB_1845779, HPA027233: AB_1845780" "unprognostic (2.88e-3)" "unprognostic (1.49e-1)" "unprognostic (1.41e-1)" "unprognostic (5.96e-2)" "unprognostic (6.86e-2)" "unprognostic (2.39e-1)" "unprognostic (8.66e-2)" "unprognostic (1.57e-1)" "unprognostic (4.66e-1)" "unprognostic (2.84e-2)" "unprognostic (1.16e-1)" "unprognostic (5.73e-1)" "prognostic favorable (3.76e-4)" "unprognostic (4.36e-2)" "unprognostic (9.22e-2)" "unprognostic (3.17e-2)" "prognostic favorable (9.38e-4)" ESM1 ENSG00000164283 "Endothelial cell specific molecule 1" Q9NQ30 5 54977867-55022671 "Predicted secreted proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 19.2;thyroid gland: 16.8" "Cell type enhanced" "Detected in some" "Ductal cells: 18.2;Endothelial cells: 81.9;Mucus glandular cells: 21.5;Pancreatic endocrine cells: 17.0" "Cancer enriched" "Detected in all" 8 "renal cancer: 65.8" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "NK-cell: 1.4" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "ovarian cancer: 67.4;Sarcoma: 47.6;thyroid cancer: 85.4" "Low region specificity" "Detected in single" "Region enhanced" "Detected in some" "midbrain: 3.6" CAB047364 Approved "Secreted to blood" "Developmental protein" NA NA 1540000 340000 "Cluster 1: T-cells - Unknown function" "Cluster 52: Kidney - Transmembrane transport" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Non-specific - Mixed function" 7 "CAB047364: " "unprognostic (4.70e-2)" "prognostic unfavorable (2.11e-7)" "unprognostic (2.63e-3)" "unprognostic (2.31e-3)" "unprognostic (4.68e-2)" "unprognostic (1.55e-1)" "unprognostic (6.85e-3)" "unprognostic (1.59e-2)" "unprognostic (1.05e-1)" "unprognostic (1.78e-3)" "unprognostic (1.18e-1)" "unprognostic (1.46e-2)" "prognostic unfavorable (4.00e-4)" "unprognostic (7.77e-2)" "unprognostic (1.09e-1)" "unprognostic (7.84e-2)" "unprognostic (2.94e-1)" F3 "CD142, TF" ENSG00000117525 "Coagulation factor III, tissue factor" P13726 1 94529173-94541759 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Blood coagulation, Hemostasis" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 673.7;Basal respiratory cells: 344.3;Club cells: 387.7;Exocrine glandular cells: 355.4;Ionocytes: 309.6;Peritubular cells: 505.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 655.6" "Kidney - Podocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009438, HPA049292, HPA069132" Uncertain Approved Vesicles "Secreted to blood" "Blood coagulation" NA NA 603000 "Cluster 64: Neuronal - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 2 Vesicles "CAB009438: AB_668005, HPA049292: AB_2680701, HPA069132: AB_2686092" "unprognostic (3.86e-2)" "unprognostic (1.19e-1)" "unprognostic (8.04e-2)" "unprognostic (1.64e-1)" "unprognostic (2.69e-2)" "unprognostic (1.23e-3)" "unprognostic (4.93e-2)" "unprognostic (8.00e-2)" "unprognostic (5.88e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (1.07e-4)" "unprognostic (1.25e-1)" "prognostic unfavorable (2.02e-8)" "unprognostic (4.84e-2)" "unprognostic (4.08e-1)" "unprognostic (1.23e-1)" "unprognostic (1.08e-1)" FAM25C bA164N7.4 ENSG00000276430 "Family with sequence similarity 25 member C" B3EWG5 10 47995322-47999791 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "cervix: 14.3;esophagus: 29.3;salivary gland: 14.9;skin 1: 42.2;vagina: 13.0" "Cell type enhanced" "Detected in single" "Suprabasal keratinocytes: 1.1" "Cancer enriched" "Detected in single" 5 "head and neck cancer: 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 7.3;head and neck cancer: 2.9" HPA044808 Uncertain NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 16 "HPA044808: AB_2679096" "unprognostic (2.93e-1)" "unprognostic (2.21e-1)" FAM32A "DKFZP586O0120, OTAG-12" ENSG00000105058 "Family with sequence similarity 32 member A" Q9Y421 19 16185380-16192046 "Predicted intracellular proteins" "Apoptosis, Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051712 Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 38: Sub-cortical - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" 1 "Nucleoplasm, Nucleoli" "HPA051712: AB_2681582" "unprognostic (3.20e-2)" "unprognostic (1.44e-3)" "unprognostic (1.25e-1)" "unprognostic (1.16e-3)" "unprognostic (1.23e-2)" "unprognostic (2.75e-1)" "unprognostic (3.31e-2)" "unprognostic (1.37e-2)" "unprognostic (3.86e-3)" "unprognostic (1.18e-3)" "unprognostic (1.56e-1)" "unprognostic (9.31e-2)" "unprognostic (3.23e-2)" "unprognostic (4.27e-2)" "unprognostic (1.51e-1)" "unprognostic (1.60e-2)" "unprognostic (6.49e-3)" FAM3C "GS3876, ILEI" ENSG00000196937 "FAM3 metabolism regulating signaling molecule C" Q92520 7 121348878-121396364 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Developmental protein" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 303.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "memory B-cell: 22.6;naive B-cell: 20.1" "Lineage enriched" "Detected in many" 7 "B-cells: 22.6" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043376, HPA050548" Enhanced Enhanced "Golgi apparatus" "Secreted in other tissues" "Developmental protein" NA NA 48000000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 45 "Golgi apparatus" "HPA043376: AB_2678452, HPA050548: AB_2681169" "unprognostic (9.44e-2)" "unprognostic (3.91e-1)" "unprognostic (1.75e-1)" "unprognostic (8.11e-3)" "unprognostic (1.26e-2)" "unprognostic (3.09e-3)" "unprognostic (3.38e-3)" "unprognostic (2.44e-1)" "unprognostic (2.95e-1)" "unprognostic (1.22e-2)" "unprognostic (2.15e-3)" "unprognostic (1.90e-1)" "unprognostic (1.58e-1)" "unprognostic (1.48e-1)" "unprognostic (9.60e-2)" "unprognostic (1.04e-1)" "unprognostic (1.06e-2)" FBXL19 "CXXC11, DKFZp434K0410, Fbl19, JHDM1C" ENSG00000099364 "F-box and leucine rich repeat protein 19" Q6PCT2 16 30923055-30948783 "Predicted intracellular proteins" "Ubl conjugation pathway" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Liver - Vascular Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074250 Approved Nucleoplasm NA No "Cluster 2: Dendritic cells - Unknown function" "Cluster 5: Brain & Testis - Signal transduction" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" Nucleoplasm "HPA074250: " "unprognostic (1.37e-1)" "prognostic unfavorable (3.27e-4)" "unprognostic (1.03e-1)" "unprognostic (3.80e-2)" "unprognostic (1.40e-1)" "unprognostic (2.20e-1)" "prognostic unfavorable (3.54e-4)" "unprognostic (3.61e-2)" "unprognostic (2.52e-1)" "unprognostic (2.89e-1)" "unprognostic (1.48e-1)" "unprognostic (6.95e-3)" "unprognostic (1.37e-3)" "unprognostic (6.02e-2)" "unprognostic (1.60e-1)" "unprognostic (2.45e-2)" "unprognostic (2.38e-2)" FBXO2 "Fbg1, Fbs1, FBX2, Nfb42, OCP1" ENSG00000116661 "F-box protein 2" Q9UK22 1 11637018-11655785 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 296.0;choroid plexus: 92.9;pancreas: 84.4;pituitary gland: 115.2" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 140.8;Exocrine glandular cells: 355.1;Hepatocytes: 113.3;Pancreatic endocrine cells: 115.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "cervical cancer: 82.5" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005472 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Non-specific - Mixed function" 2 "Nucleoplasm, Cytosol" "HPA005472: AB_2667332" "unprognostic (2.02e-2)" "unprognostic (1.28e-1)" "unprognostic (2.10e-1)" "unprognostic (8.13e-3)" "unprognostic (1.80e-1)" "unprognostic (2.61e-2)" "unprognostic (4.01e-2)" "unprognostic (1.30e-2)" "unprognostic (1.18e-2)" "unprognostic (1.41e-1)" "unprognostic (5.44e-2)" "unprognostic (1.68e-2)" "prognostic favorable (3.45e-6)" "unprognostic (5.26e-2)" "unprognostic (5.21e-2)" "unprognostic (4.82e-2)" "unprognostic (1.64e-1)" FERMT1 "C20orf42, FLJ20116, KIND1, UNC112A, URP1" ENSG00000101311 "FERM domain containing kindlin 1" Q9BQL6 20 6074845-6123214 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 30.9" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 100.4;Cytotrophoblasts: 70.0;Oligodendrocyte precursor cells: 215.5;Squamous epithelial cells: 67.5;Suprabasal keratinocytes: 63.6;Undifferentiated cells: 81.6" "Cancer enhanced" "Detected in all" "colorectal cancer: 59.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (other), Thyroid - Thyroid glandular cells" "Region enriched" "Detected in single" 5 "hippocampal formation: 2.0" "Not detected" "Not detected" "HPA039778, HPA041966" Approved NA NA "Cluster 45: Intestine - Digestion" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" "HPA039778: AB_10805593, HPA041966: AB_10795387" "unprognostic (1.08e-3)" "unprognostic (4.63e-2)" "unprognostic (1.03e-1)" "unprognostic (3.64e-3)" "unprognostic (1.75e-3)" "unprognostic (2.82e-1)" "unprognostic (9.49e-2)" "unprognostic (1.53e-3)" "unprognostic (2.13e-1)" "unprognostic (1.83e-1)" "prognostic unfavorable (6.60e-4)" "unprognostic (4.38e-2)" "unprognostic (1.31e-1)" "unprognostic (2.11e-2)" "unprognostic (2.04e-1)" "unprognostic (4.60e-2)" "unprognostic (5.33e-2)" FGD6 "FLJ11183, ZFYVE24" ENSG00000180263 "FYVE, RhoGEF and PH domain containing 6" Q6ZV73 12 95076749-95217482 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 103.4;Microglial cells: 86.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 2.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007974 Approved Approved Vesicles NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" Vesicles "HPA007974: AB_1848520" "unprognostic (1.28e-2)" "unprognostic (2.67e-3)" "unprognostic (6.06e-2)" "unprognostic (5.56e-2)" "unprognostic (1.65e-1)" "unprognostic (4.70e-2)" "unprognostic (4.66e-2)" "unprognostic (1.35e-3)" "unprognostic (1.32e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (4.62e-5)" "prognostic unfavorable (9.83e-4)" "prognostic unfavorable (5.46e-6)" "unprognostic (1.01e-2)" "unprognostic (1.38e-1)" "unprognostic (3.33e-2)" "unprognostic (1.92e-1)" FGF19 ENSG00000162344 "Fibroblast growth factor 19" O95750 11 69698238-69704022 "Cancer-related genes, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "gallbladder: 229.2" "Group enriched" "Detected in some" 5 "Cholangiocytes: 34.3;Ductal cells: 14.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 31.1;Gastric cancer: 26.0" "Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" HPA036082 Approved "Secreted to blood" "Growth factor" NA NA 133000 "Cluster 62: Connective tissue - ECM organization" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 45: Non-specific - Mixed function" "HPA036082: AB_10669665" "unprognostic (7.46e-3)" "unprognostic (2.43e-3)" "unprognostic (5.52e-3)" "unprognostic (1.22e-1)" "unprognostic (4.68e-3)" "unprognostic (6.45e-2)" "unprognostic (5.72e-3)" "unprognostic (2.26e-1)" "unprognostic (6.39e-3)" "unprognostic (1.66e-2)" "unprognostic (8.82e-3)" FIBCD1 FLJ14810 ENSG00000130720 "Fibrinogen C domain containing 1" Q8N539 9 130902438-130939286 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "adrenal gland: 9.6;brain: 24.8;parathyroid gland: 12.1;testis: 6.4" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 10.7;Early spermatids: 21.5;Exocrine glandular cells: 12.2;Horizontal cells: 12.6;Intestinal goblet cells: 19.2;Late spermatids: 33.3;monocytes: 10.4;Spermatogonia: 16.8;Undifferentiated cells: 13.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "hippocampal formation: 60.3" "Immune cell enriched" "Detected in single" 6 "non-classical monocyte: 1.1" "Lineage enriched" "Detected in single" 11 "monocytes: 1.1" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 43.7" "Testis - Sertoli cells" "Group enriched" "Detected in many" 4 "basal ganglia: 17.6;hippocampal formation: 68.5" "Region enriched" "Detected in many" 5 "hippocampal formation: 74.6" HPA055353 Approved Approved "Cell Junctions" NA NA 19000000 "Cluster 61: Brain - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 45: Non-specific - Mixed function" 1 "Cell Junctions" "HPA055353: AB_2682791" "unprognostic (1.18e-3)" "unprognostic (2.70e-1)" "unprognostic (4.69e-2)" "unprognostic (5.63e-2)" "unprognostic (9.11e-2)" "unprognostic (1.62e-1)" "unprognostic (4.16e-5)" "unprognostic (1.83e-3)" "unprognostic (3.14e-1)" "unprognostic (1.28e-1)" "unprognostic (2.05e-2)" "unprognostic (4.45e-2)" "unprognostic (1.42e-6)" "unprognostic (1.66e-1)" "unprognostic (5.53e-2)" "unprognostic (6.68e-3)" "unprognostic (2.77e-1)" FKBP1B "FKBP12.6, FKBP1L, FKBP9, OTK4, PPIase" ENSG00000119782 "FKBP prolyl isomerase 1B" P68106 2 24049701-24063681 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 68.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 2.2;T-reg: 2.8" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "testis cancer: 42.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045572, HPA051798" Uncertain Approved Vesicles NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 61: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 45: Non-specific - Mixed function" 6 Vesicles "HPA045572: AB_2732521, HPA051798: AB_2681615" "unprognostic (3.01e-3)" "unprognostic (3.35e-1)" "unprognostic (7.05e-2)" "unprognostic (9.89e-3)" "unprognostic (1.47e-2)" "unprognostic (2.10e-1)" "unprognostic (2.23e-2)" "unprognostic (9.19e-2)" "unprognostic (1.29e-1)" "unprognostic (2.90e-1)" "unprognostic (9.55e-2)" "unprognostic (1.08e-1)" "unprognostic (1.12e-1)" "unprognostic (7.53e-2)" "unprognostic (3.43e-2)" "unprognostic (2.85e-2)" "unprognostic (1.45e-1)" FLII "FLI, Fli1, FLIL, MGC39265" ENSG00000177731 "FLII actin remodeling protein" Q13045 17 18244815-18258738 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Actin-binding, Activator, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 236.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007084, HPA008903, CAB016132" Enhanced Enhanced "Nucleoplasm,Centriolar satellite,Cytosol" NA NA 150000 "Cluster 40: Monocytes - Innate immune response" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 45: Non-specific - Mixed function" 1 "Nucleoplasm, Centriolar satellite, Cytosol" "CAB016132: AB_627613, HPA007084: AB_1848638, HPA008903: AB_1848640" "unprognostic (8.09e-2)" "unprognostic (1.09e-2)" "unprognostic (6.89e-2)" "unprognostic (2.53e-2)" "unprognostic (4.22e-2)" "unprognostic (4.78e-2)" "unprognostic (1.88e-2)" "unprognostic (1.23e-2)" "unprognostic (4.91e-2)" "unprognostic (1.36e-2)" "unprognostic (1.28e-1)" "unprognostic (2.47e-3)" "unprognostic (4.03e-2)" "unprognostic (1.17e-1)" "unprognostic (2.36e-1)" "unprognostic (2.06e-1)" "unprognostic (3.39e-2)" FLNB "ABP-278, FH1, FLN1L, LRS1, TABP, TAP" ENSG00000136068 "Filamin B" O75369 3 58008398-58172251 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Differentiation, Myogenesis" "Actin-binding, Developmental protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 294.8;Extravillous trophoblasts: 244.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004747, HPA004886, CAB019322" Enhanced Supported "Golgi apparatus,Plasma membrane,Actin filaments,Cytosol" NA NA 20000000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 45: Intestine - Digestion" "Cluster 6: Non-specific - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 8 "Plasma membrane" "Golgi apparatus, Actin filaments, Cytosol" "CAB019322: , HPA004747: AB_1848599, HPA004886: AB_1848600" "unprognostic (1.29e-2)" "unprognostic (1.08e-2)" "unprognostic (5.97e-2)" "unprognostic (6.86e-2)" "unprognostic (1.26e-1)" "unprognostic (2.05e-1)" "unprognostic (6.52e-2)" "unprognostic (1.72e-1)" "unprognostic (9.61e-2)" "unprognostic (5.02e-3)" "prognostic unfavorable (8.45e-5)" "unprognostic (9.23e-2)" "prognostic favorable (3.45e-6)" "unprognostic (4.38e-2)" "unprognostic (1.36e-1)" "unprognostic (6.65e-3)" "unprognostic (2.33e-1)" FPGS ENSG00000136877 "Folylpolyglutamate synthase" Q05932 9 127794597-127814327 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "One-carbon metabolism" Ligase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Mesothelial cells: 79.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050488 Approved "Intracellular and membrane" Enzyme NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 45: Non-specific - Mixed function" "HPA050488: AB_2681143" "unprognostic (6.37e-2)" "unprognostic (1.06e-1)" "unprognostic (1.02e-1)" "prognostic favorable (9.08e-4)" "unprognostic (1.25e-1)" "unprognostic (2.67e-1)" "unprognostic (1.00e-1)" "unprognostic (1.89e-1)" "unprognostic (6.25e-2)" "unprognostic (2.63e-1)" "unprognostic (1.16e-1)" "unprognostic (6.97e-2)" "unprognostic (1.76e-1)" "unprognostic (8.54e-3)" "unprognostic (2.61e-1)" "unprognostic (1.58e-1)" "unprognostic (1.55e-2)" FXYD5 OIT2 ENSG00000089327 "FXYD domain containing ion transport regulator 5" Q96DB9 19 35154730-35169881 "Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 544.4;granulocytes: 591.8;Hofbauer cells: 595.4;Langerhans cells: 530.8;monocytes: 536.6;T-cells: 464.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Colon - Endothelial cells, Liver - Vascular Endothelial cells" HPA010817 Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 7: Adipose tissue - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 69: Skin cancer - ECM organization" "Cluster 45: Non-specific - Mixed function" "Endoplasmic reticulum" "HPA010817: AB_1849214" "unprognostic (3.97e-3)" "unprognostic (5.49e-2)" "unprognostic (6.37e-3)" "unprognostic (3.01e-1)" "unprognostic (2.50e-3)" "unprognostic (4.39e-3)" "unprognostic (4.68e-2)" "unprognostic (1.56e-3)" "unprognostic (3.85e-1)" "unprognostic (5.66e-3)" "unprognostic (4.78e-2)" "unprognostic (4.75e-2)" "prognostic unfavorable (3.71e-9)" "unprognostic (6.07e-2)" "unprognostic (7.88e-2)" "unprognostic (3.61e-2)" "unprognostic (1.74e-1)" GAL "GAL-GMAP, GALN, GLNN, GMAP" ENSG00000069482 "Galanin and GMAP prepropeptide" P22466 11 68683779-68691175 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Hormone, Neuropeptide" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "pituitary gland: 862.3" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 31.2;Ductal cells: 29.4;Endometrial stromal cells: 52.1;Exocrine glandular cells: 28.7;Extravillous trophoblasts: 55.9;Glandular and luminal cells: 25.1;Pancreatic endocrine cells: 86.6" "Cancer enhanced" "Detected in many" "testis cancer: 22.2" "Region enriched" "Detected in all" 13 "hypothalamus: 1423.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 257.1" "Colon - Colon enteroendocrine cells, Skin - Sebaceous gland cells" "Region enhanced" "Detected in many" "hypothalamus: 82.6" "Low region specificity" "Detected in many" "HPA049864, CAB079779" Enhanced Supported Supported "Golgi apparatus,Vesicles" "Secreted to blood" Hormone NA NA 60000 200000 "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 45: Non-specific - Mixed function" 6 "Golgi apparatus" Vesicles "CAB079779: , HPA049864: AB_2680922" "unprognostic (8.56e-2)" "unprognostic (1.45e-2)" "unprognostic (7.50e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (2.70e-1)" "unprognostic (2.27e-2)" "unprognostic (8.07e-3)" "prognostic unfavorable (8.17e-4)" "unprognostic (5.98e-2)" "unprognostic (1.07e-2)" "unprognostic (8.84e-2)" "unprognostic (7.42e-2)" "unprognostic (1.20e-1)" "unprognostic (8.85e-2)" "unprognostic (7.88e-2)" "unprognostic (5.38e-2)" "unprognostic (3.24e-2)" GALNT3 "GalNAc-T3, HFTC, HHS" ENSG00000115339 "Polypeptide N-acetylgalactosaminyltransferase 3" Q14435 2 165747588-165794659 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 75.3" "Cell type enhanced" "Detected in many" "Early spermatids: 172.5;Intestinal goblet cells: 140.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 50.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose visceral - T-cells, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA007613 Enhanced Supported "Golgi apparatus" NA NA 440000 "Cluster 32: Basophils - Transcription" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 39: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" "Golgi apparatus" "HPA007613: AB_1078941" "unprognostic (1.95e-1)" "prognostic unfavorable (2.08e-4)" "unprognostic (1.16e-3)" "unprognostic (2.78e-1)" "unprognostic (3.22e-2)" "prognostic unfavorable (4.10e-4)" "unprognostic (4.13e-2)" "unprognostic (4.47e-2)" "unprognostic (2.74e-1)" "unprognostic (6.44e-2)" "unprognostic (3.62e-3)" "unprognostic (1.33e-1)" "unprognostic (1.14e-2)" "unprognostic (1.79e-2)" "unprognostic (3.54e-1)" "unprognostic (1.28e-1)" "unprognostic (1.57e-1)" GAPDH GAPD ENSG00000111640 "Glyceraldehyde-3-phosphate dehydrogenase" P04406 12 6534512-6538374 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Glycolysis, Immunity, Innate immunity, Translation regulation" "Oxidoreductase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "skeletal muscle: 26611.3;tongue: 18150.7" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 11520.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005197, CAB016392, HPA040067, HPA061280, CAB079968" Supported Enhanced "Nuclear membrane,Vesicles,Plasma membrane,Cytosol" No No 1400000000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 27: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" 28 "Plasma membrane, Cytosol" "Nuclear membrane, Vesicles" "CAB005197: AB_641107, CAB016392: AB_627678, CAB079968: , HPA040067: AB_10965903, HPA061280: AB_2684463" "unprognostic (3.03e-1)" "unprognostic (2.62e-3)" "unprognostic (3.58e-2)" "unprognostic (4.20e-1)" "unprognostic (9.73e-3)" "unprognostic (1.77e-3)" "prognostic unfavorable (1.79e-6)" "unprognostic (2.89e-3)" "unprognostic (2.86e-1)" "unprognostic (2.06e-2)" "unprognostic (9.50e-3)" "unprognostic (4.52e-1)" "prognostic unfavorable (6.25e-10)" "unprognostic (2.33e-1)" "unprognostic (4.28e-1)" "unprognostic (1.40e-1)" "unprognostic (1.26e-2)" GBP3 FLJ10961 ENSG00000117226 "Guanylate binding protein 3" Q9H0R5 1 89006679-89022894 "Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 76.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 92.5;Ductal cells: 56.1;Proximal enterocytes: 112.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" HPA045657 Approved NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 45: Intestine - Digestion" "Cluster 39: Astrocytes - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 45: Non-specific - Mixed function" 4 "HPA045657: AB_10961631" "unprognostic (1.14e-2)" "unprognostic (2.23e-1)" "unprognostic (6.30e-2)" "unprognostic (1.25e-1)" "unprognostic (4.06e-2)" "unprognostic (2.02e-1)" "unprognostic (2.18e-1)" "unprognostic (4.39e-2)" "unprognostic (3.47e-1)" "unprognostic (7.44e-2)" "unprognostic (4.42e-2)" "unprognostic (1.98e-1)" "unprognostic (1.86e-2)" "unprognostic (1.66e-2)" "unprognostic (9.70e-3)" "unprognostic (3.06e-2)" "unprognostic (5.06e-3)" GGT1 "CD224, D22S672, D22S732, GGT" ENSG00000100031 "Gamma-glutamyltransferase 1" P19440 22 24594811-24629005 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis, Lipid metabolism" "Acyltransferase, Hydrolase, Protease, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 173.5;liver: 113.1" "Group enriched" "Detected in some" 4 "Distal enterocytes: 23.8;Ductal cells: 57.7;Exocrine glandular cells: 30.0;Proximal enterocytes: 49.9" "Cancer enhanced" "Detected in all" "renal cancer: 37.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney cancer: 119.6" "Kidney - Proximal tubular cells, Prostate - Prostate glandular cells, Stomach - Chief cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045635, HPA047534, HPA065444" Supported Uncertain Vesicles "Intracellular and membrane" Enzyme NA NA 3600000 "Cluster 28: Neutrophils - Unknown function" "Cluster 52: Kidney - Transmembrane transport" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" Vesicles "HPA045635: AB_2679400, HPA047534: AB_2680079, HPA065444: AB_2685491" "unprognostic (8.13e-3)" "unprognostic (4.76e-1)" "unprognostic (8.29e-2)" "unprognostic (1.28e-2)" "unprognostic (3.70e-2)" "unprognostic (1.43e-2)" "unprognostic (5.60e-3)" "unprognostic (1.68e-1)" "unprognostic (2.21e-1)" "prognostic favorable (7.44e-4)" "unprognostic (4.55e-2)" "unprognostic (2.55e-2)" "prognostic favorable (4.83e-4)" "unprognostic (1.44e-2)" "unprognostic (5.37e-2)" "unprognostic (1.74e-1)" "unprognostic (6.10e-2)" GJB4 CX30.3 ENSG00000189433 "Gap junction protein beta 4" Q9NTQ9 1 34759740-34762327 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 42.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 4.0;Basal prostatic cells: 3.7;Basal respiratory cells: 12.7;Ciliated cells: 3.0;Club cells: 6.5;Distal tubular cells: 3.1;Ionocytes: 6.6;Squamous epithelial cells: 3.2;Suprabasal keratinocytes: 3.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 10.9;pancreatic cancer: 11.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA055112, HPA073904" Enhanced Supported "Cell Junctions" NA NA "Cluster 13: Skin - Cornification" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 8 "Cell Junctions" "HPA055112: AB_2682699, HPA073904: " "unprognostic (3.30e-2)" "prognostic favorable (5.48e-4)" "unprognostic (1.57e-1)" "unprognostic (2.70e-2)" "unprognostic (4.21e-2)" "unprognostic (2.22e-1)" "unprognostic (2.16e-2)" "unprognostic (2.18e-2)" "unprognostic (5.40e-2)" "unprognostic (3.65e-1)" "prognostic unfavorable (3.24e-5)" "unprognostic (3.73e-2)" "unprognostic (5.81e-3)" "unprognostic (1.26e-1)" "unprognostic (1.67e-1)" "unprognostic (3.52e-4)" "unprognostic (5.42e-2)" GLRX3 "bA500G10.4, GLRX4, GRX3, GRX4, PICOT, TXNL2" ENSG00000108010 "Glutaredoxin 3" O76003 10 130136391-130184521 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 285.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028941 Approved NA NA 350000 "Cluster 33: Non-specific - ATP binding" "Cluster 4: Testis - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 45: Non-specific - Mixed function" 78 "HPA028941: AB_10601015" "unprognostic (7.11e-3)" "unprognostic (4.02e-2)" "unprognostic (1.67e-2)" "unprognostic (5.39e-3)" "unprognostic (5.66e-2)" "unprognostic (1.50e-2)" "prognostic unfavorable (9.03e-6)" "unprognostic (9.29e-2)" "unprognostic (1.13e-1)" "unprognostic (5.76e-2)" "unprognostic (1.46e-3)" "unprognostic (1.08e-3)" "prognostic unfavorable (9.24e-6)" "unprognostic (4.01e-1)" "unprognostic (1.20e-1)" "unprognostic (7.57e-2)" "unprognostic (1.11e-1)" GNG5 ENSG00000174021 "G protein subunit gamma 5" P63218 1 84498323-84506581 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "CAB032623, HPA043651" Approved NA NA 37000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 56: Non-specific - Unknown function" "Cluster 8: Immune cells - Immune response" "Cluster 37: Non-specific - mRNA processing" "Cluster 45: Non-specific - Mixed function" 6 "CAB032623: AB_2109919, HPA043651: AB_2678600" "unprognostic (1.82e-2)" "unprognostic (9.27e-2)" "unprognostic (2.87e-2)" "unprognostic (2.75e-3)" "unprognostic (6.19e-2)" "unprognostic (2.87e-1)" "prognostic unfavorable (3.23e-5)" "unprognostic (1.59e-1)" "unprognostic (9.28e-2)" "unprognostic (8.93e-3)" "unprognostic (2.32e-2)" "unprognostic (1.70e-1)" "unprognostic (1.72e-3)" "unprognostic (1.64e-1)" "unprognostic (6.51e-2)" "unprognostic (3.44e-2)" "unprognostic (4.22e-2)" GOLM1 "bA379P1.3, C9orf155, FLJ23608, GOLPH2, GP73" ENSG00000135052 "Golgi membrane protein 1" Q8NBJ4 9 86026146-86100173 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "stomach 1: 386.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 397.1;Gastric mucus-secreting cells: 240.5;Late spermatids: 447.2;Paneth cells: 244.4" "Cancer enhanced" "Detected in all" "prostate cancer: 343.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 2.2;classical monocyte: 3.5;gdT-cell: 3.5;intermediate monocyte: 2.6;neutrophil: 4.3;non-classical monocyte: 4.2;plasmacytoid DC: 1.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010638, HPA011929, CAB015341" Enhanced Enhanced "Golgi apparatus" "Intracellular and membrane" "No annotated function" NA NA 81000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 45: Intestine - Digestion" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 7: Liver cancer - Metabolism" "Cluster 45: Non-specific - Mixed function" 45 "Golgi apparatus" "CAB015341: AB_2113334, HPA010638: AB_1849886, HPA011929: AB_1849888" "unprognostic (1.47e-1)" "unprognostic (2.31e-2)" "unprognostic (1.10e-1)" "prognostic favorable (8.14e-5)" "unprognostic (1.97e-1)" "unprognostic (4.40e-3)" "prognostic unfavorable (1.30e-4)" "unprognostic (4.89e-3)" "unprognostic (2.81e-1)" "unprognostic (1.44e-1)" "unprognostic (1.20e-1)" "unprognostic (1.34e-2)" "unprognostic (5.59e-3)" "unprognostic (1.52e-1)" "unprognostic (1.25e-1)" "unprognostic (2.87e-3)" "unprognostic (1.23e-1)" HCCS "CCHL, MLS" ENSG00000004961 "Holocytochrome c synthase" P53701 X 11111301-11123086 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Lyase "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002946 Approved Enhanced Mitochondria "Intracellular and membrane" Enzyme NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 35: Non-specific - Mitochondria" "Cluster 23: Choroid plexus - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 45: Non-specific - Mixed function" 5 Mitochondria "HPA002946: AB_1079041" "prognostic unfavorable (8.69e-5)" "unprognostic (6.89e-3)" "unprognostic (8.46e-3)" "unprognostic (4.92e-2)" "unprognostic (1.34e-1)" "unprognostic (5.44e-2)" "prognostic unfavorable (1.35e-5)" "unprognostic (9.18e-2)" "unprognostic (2.73e-1)" "unprognostic (2.52e-2)" "unprognostic (2.10e-2)" "unprognostic (1.60e-1)" "prognostic favorable (6.17e-8)" "unprognostic (2.66e-2)" "unprognostic (1.52e-1)" "unprognostic (2.04e-1)" "unprognostic (1.93e-2)" HDAC1 "GON-10, HD1, KDAC1, RPD3L1" ENSG00000116478 "Histone deacetylase 1" Q13547 1 32292083-32333635 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005017, HPA029693, CAB068191" Enhanced Enhanced Nucleoplasm NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 39: Astrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 45: Non-specific - Mixed function" 63 Nucleoplasm "CAB005017: AB_2248344, CAB068191: AB_2665664, HPA029693: AB_10601659" "unprognostic (2.51e-2)" "unprognostic (9.10e-2)" "unprognostic (2.92e-1)" "unprognostic (2.98e-1)" "unprognostic (9.15e-2)" "unprognostic (3.57e-3)" "prognostic unfavorable (5.76e-7)" "unprognostic (9.57e-2)" "unprognostic (5.02e-2)" "unprognostic (3.47e-2)" "unprognostic (7.06e-2)" "unprognostic (4.44e-2)" "prognostic unfavorable (1.04e-5)" "unprognostic (6.86e-2)" "unprognostic (3.78e-1)" "unprognostic (7.16e-2)" "unprognostic (1.72e-1)" HDGF HMG1L2 ENSG00000143321 "Heparin binding growth factor" P51858 1 156742109-156766925 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Transcription, Transcription regulation" "DNA-binding, Growth factor, Heparin-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026035, HPA048728, HPA053422" Enhanced Enhanced Nucleoplasm "Secreted to blood" "Growth factor" NA NA 790000 "Cluster 29: Non-specific - Unknown function" "Cluster 56: Non-specific - Unknown function" "Cluster 55: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 45: Non-specific - Mixed function" Nucleoplasm "CAB026035: , HPA048728: AB_2680503, HPA053422: AB_2682146" "unprognostic (2.80e-1)" "unprognostic (9.63e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (6.02e-4)" "unprognostic (9.06e-2)" "unprognostic (2.14e-1)" "prognostic unfavorable (2.43e-8)" "unprognostic (9.80e-3)" "unprognostic (2.34e-2)" "prognostic favorable (9.84e-4)" "unprognostic (2.45e-3)" "unprognostic (3.67e-2)" "unprognostic (1.40e-3)" "unprognostic (8.66e-3)" "unprognostic (2.14e-1)" "unprognostic (2.06e-1)" "unprognostic (3.86e-2)" HMGA1 HMGIY ENSG00000137309 "High mobility group AT-hook 1" P17096 6 34236873-34246231 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 267.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 932.6;Ductal cells: 622.5;Extravillous trophoblasts: 701.2;Syncytiotrophoblasts: 692.3;Undifferentiated cells: 538.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Urothelial cells, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB032200, HPA065612, HPA068442" Enhanced Supported Nucleoplasm,Nucleoli NA NA 72000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Non-specific - Mixed function" 3 Nucleoplasm Nucleoli "CAB032200: AB_2117771, HPA065612: , HPA068442: " "unprognostic (1.81e-1)" "unprognostic (1.25e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (7.13e-4)" "unprognostic (1.57e-1)" "unprognostic (1.20e-3)" "prognostic unfavorable (1.29e-6)" "prognostic unfavorable (3.36e-4)" "unprognostic (8.54e-2)" "unprognostic (1.84e-2)" "prognostic unfavorable (8.71e-4)" "unprognostic (1.55e-1)" "unprognostic (8.22e-2)" "unprognostic (4.52e-3)" "unprognostic (1.19e-1)" "unprognostic (4.37e-1)" "unprognostic (2.65e-2)" HTR3A "5-HT3A, 5-HT3R, HTR3" ENSG00000166736 "5-hydroxytryptamine receptor 3A" P46098 11 113975075-113990313 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 2.5;intestine: 2.0;lymphoid tissue: 7.8;pancreas: 2.5;salivary gland: 4.8" "Group enriched" "Detected in some" 5 "Ductal cells: 25.0;Exocrine glandular cells: 71.5;Pancreatic endocrine cells: 23.8" "Cancer enriched" "Detected in many" 7 "ovarian cancer: 15.2" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 15 "memory B-cell: 3.9;naive B-cell: 13.9;plasmacytoid DC: 11.6" "Group enriched" "Detected in many" 128 "B-cells: 13.9;dendritic cells: 11.6" "Group enriched" "Detected in some" 9 "lymphoma: 15.4;Neuroblastoma: 12.9" "Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 12 "amygdala: 2.7;cerebral cortex: 4.1;hippocampal formation: 3.9" HPA069442 Supported NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 51: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 45: Non-specific - Mixed function" 3 "HPA069442: AB_2732132" "unprognostic (6.46e-3)" "prognostic favorable (6.26e-4)" "unprognostic (1.09e-1)" "prognostic unfavorable (1.26e-4)" "unprognostic (3.36e-3)" "unprognostic (8.36e-3)" "unprognostic (1.65e-5)" "unprognostic (1.46e-2)" "unprognostic (8.87e-2)" "unprognostic (6.21e-2)" "unprognostic (6.80e-3)" "unprognostic (3.00e-2)" "unprognostic (1.65e-2)" "unprognostic (8.72e-2)" "unprognostic (2.01e-1)" "unprognostic (3.79e-1)" "unprognostic (3.40e-2)" IFNK ENSG00000147896 "Interferon kappa" Q9P0W0 9 27524290-27526498 "Predicted intracellular proteins, Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "cervical cancer: 0.5;head and neck cancer: 0.6;urothelial cancer: 0.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 35 "Bladder cancer: 3.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to blood" Interferon NA NA "Cluster 11: White matter - Signal transduction" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 45: Non-specific - Mixed function" "unprognostic (5.58e-3)" "unprognostic (4.64e-3)" "unprognostic (1.06e-1)" IL11 "AGIF, IL-11" ENSG00000095752 "Interleukin 11" P20809 19 55364382-55370463 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.4" "Cell type enriched" "Detected in some" 4 "Pancreatic endocrine cells: 127.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Secreted to blood" Interleukin NA NA 34800 "Cluster 65: Cerebellum - Nervous system development" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Non-specific - Mixed function" 3 "unprognostic (6.60e-3)" "unprognostic (7.23e-3)" "unprognostic (1.12e-1)" "unprognostic (3.18e-3)" "unprognostic (3.32e-3)" "unprognostic (6.33e-2)" "unprognostic (1.04e-2)" "unprognostic (7.84e-5)" "unprognostic (2.47e-1)" "unprognostic (2.52e-1)" "prognostic unfavorable (7.50e-4)" "unprognostic (4.83e-2)" "unprognostic (4.07e-8)" "unprognostic (1.23e-1)" "unprognostic (1.41e-1)" "unprognostic (3.82e-3)" "unprognostic (3.08e-2)" IL23A "IL-23, IL-23A, IL23P19, P19, SGRF" ENSG00000110944 "Interleukin 23 subunit alpha" Q9NPF7 12 56334174-56340410 "FDA approved drug targets, Predicted secreted proteins" "Antiviral defense, Immunity, Inflammatory response, Innate immunity, Tissue remodeling" Cytokine "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "urinary bladder: 42.8" "Cell type enriched" "Detected in many" 4 "Langerhans cells: 205.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "MAIT T-cell: 14.2;memory B-cell: 19.0;memory CD4 T-cell: 25.8;memory CD8 T-cell: 12.5;naive B-cell: 21.6;naive CD4 T-cell: 28.2;naive CD8 T-cell: 17.7;T-reg: 15.6" "Group enriched" "Detected in many" 12 "B-cells: 21.6;T-cells: 28.2" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Region enhanced" "Detected in some" "white matter: 3.9" "Not detected" "Not detected" HPA001554 Approved Approved Cytosol "Secreted to blood" Interleukin NA NA 11000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 3 Cytosol "HPA001554: AB_1079135" "unprognostic (2.34e-1)" "unprognostic (1.22e-1)" "unprognostic (1.27e-1)" "unprognostic (1.06e-1)" "unprognostic (5.24e-2)" "unprognostic (4.01e-3)" "unprognostic (4.40e-1)" "unprognostic (1.43e-3)" "unprognostic (1.30e-1)" "unprognostic (6.79e-2)" "unprognostic (3.38e-2)" "unprognostic (4.16e-2)" "unprognostic (3.03e-10)" "unprognostic (1.66e-1)" "unprognostic (1.08e-1)" "unprognostic (1.83e-1)" "unprognostic (4.50e-3)" IL32 "NK4, TAIF, TAIFb, TAIFd" ENSG00000008517 "Interleukin 32" P24001 16 3065297-3082192 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 808.7;pancreas: 654.9" "Cell type enhanced" "Detected in many" "Ductal cells: 1395.6;Exocrine glandular cells: 3125.9;Pancreatic endocrine cells: 3246.5;Proximal enterocytes: 4806.7;Proximal tubular cells: 5236.5;T-cells: 1635.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "T-reg: 4640.3" "Lineage enriched" "Detected in all" 8 "T-cells: 4640.3" "Cancer enhanced" "Detected in all" "Kidney cancer: 674.0" "HPA029397, CAB030029" Uncertain "Secreted to blood" Interleukin NA NA 46100 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 47: Endothelial cells - Vasculature" "Cluster 59: Leukemia - T-cell receptor" "Cluster 45: Non-specific - Mixed function" "CAB030029: AB_1089175, HPA029397: AB_10612120" "unprognostic (2.00e-2)" "unprognostic (2.89e-2)" "unprognostic (2.86e-1)" "prognostic favorable (1.33e-4)" "unprognostic (2.95e-2)" "unprognostic (1.32e-1)" "unprognostic (8.02e-2)" "unprognostic (2.58e-2)" "unprognostic (1.73e-3)" "unprognostic (2.19e-2)" "unprognostic (3.32e-3)" "unprognostic (3.51e-1)" "unprognostic (3.30e-2)" "unprognostic (8.08e-2)" "unprognostic (3.86e-2)" "unprognostic (3.16e-2)" "unprognostic (4.29e-3)" INO80B "hIes2, HMGA1L4, HMGIYL4, IES2, PAP-1BP, PAPA-1, ZNHIT4" ENSG00000115274 "INO80 complex subunit B" Q9C086 2 74455087-74457944 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA070644, HPA078274" Supported "Nucleoplasm,Nucleoli,Nuclear bodies" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 45: Non-specific - Mixed function" 49 Nucleoplasm "Nucleoli, Nuclear bodies" "HPA070644: AB_2732159, HPA078274: " "prognostic favorable (2.89e-4)" "unprognostic (2.24e-2)" "unprognostic (5.62e-2)" "unprognostic (6.59e-3)" "unprognostic (9.45e-2)" "unprognostic (3.82e-2)" "unprognostic (2.20e-3)" "unprognostic (1.21e-2)" "unprognostic (1.16e-1)" "unprognostic (1.54e-2)" "unprognostic (7.52e-3)" "unprognostic (2.18e-1)" "prognostic unfavorable (1.56e-5)" "prognostic favorable (8.44e-4)" "unprognostic (1.51e-1)" "unprognostic (3.21e-1)" "unprognostic (1.18e-3)" INSIG2 ENSG00000125629 "Insulin induced gene 2" Q9Y5U4 2 118088452-118110997 "Predicted membrane proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB033861 Uncertain NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 35: Non-specific - DNA binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 34 "CAB033861: AB_2249149" "unprognostic (3.84e-3)" "unprognostic (4.54e-3)" "unprognostic (1.84e-1)" "unprognostic (7.00e-2)" "unprognostic (6.24e-2)" "prognostic unfavorable (7.10e-4)" "unprognostic (1.80e-1)" "unprognostic (7.30e-2)" "unprognostic (7.41e-2)" "unprognostic (2.37e-1)" "prognostic unfavorable (2.19e-6)" "unprognostic (2.40e-1)" "prognostic unfavorable (4.11e-6)" "unprognostic (1.40e-1)" "unprognostic (2.65e-1)" "unprognostic (1.42e-1)" "unprognostic (3.75e-2)" ITGA2 CD49B ENSG00000164171 "Integrin subunit alpha 2" P17301 5 52989340-53094779 "Cancer-related genes, CD markers, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 144.3;Basal respiratory cells: 132.7;Ductal cells: 122.3;Exocrine glandular cells: 128.5;Mucus glandular cells: 128.1;Oligodendrocytes: 345.3;Salivary duct cells: 209.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB017690, HPA060991, HPA063556" Enhanced Approved Nucleoplasm,Cytosol Yes No 43000000 "Cluster 27: Squamous epithelium - Keratinization" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 2 Nucleoplasm Cytosol "CAB017690: AB_1124939, HPA060991: AB_2684405, HPA063556: AB_2685040" "unprognostic (8.35e-2)" "unprognostic (1.33e-1)" "unprognostic (3.85e-3)" "unprognostic (1.07e-1)" "unprognostic (1.22e-1)" "unprognostic (3.70e-2)" "unprognostic (2.67e-3)" "unprognostic (2.38e-2)" "unprognostic (1.87e-1)" "unprognostic (1.69e-2)" "prognostic unfavorable (1.02e-5)" "unprognostic (4.27e-1)" "unprognostic (3.88e-2)" "unprognostic (2.87e-2)" "unprognostic (1.84e-1)" "unprognostic (1.30e-1)" "unprognostic (1.11e-1)" ITGA3 "CD49c, GAP-B3, MSK18, VCA-2, VLA3a" ENSG00000005884 "Integrin subunit alpha 3" P26006 17 50055968-50090481 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 279.9;Ductal cells: 113.7;Exocrine glandular cells: 95.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Lung - Alveolar cells type 1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008572, CAB018594" Enhanced Supported "Plasma membrane" NA NA 170000 "Cluster 51: Thyroid gland - Unknown function" "Cluster 1: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Non-specific - Mixed function" 1 "Plasma membrane" "CAB018594: AB_668044, HPA008572: AB_2668094" "unprognostic (3.24e-3)" "prognostic unfavorable (6.75e-4)" "unprognostic (9.51e-2)" "unprognostic (3.46e-3)" "unprognostic (3.45e-3)" "prognostic unfavorable (1.36e-4)" "unprognostic (8.28e-3)" "unprognostic (2.76e-3)" "unprognostic (1.26e-3)" "unprognostic (1.82e-2)" "prognostic unfavorable (5.95e-5)" "unprognostic (7.05e-2)" "unprognostic (1.14e-1)" "unprognostic (1.93e-1)" "unprognostic (1.30e-1)" "unprognostic (1.28e-2)" "unprognostic (2.35e-2)" ITGAV "CD51, MSK8, VNRA, VTNR" ENSG00000138448 "Integrin subunit alpha V" P06756 2 186590010-186680901 "Cancer-related genes, CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 181.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "testis cancer: 265.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002499, HPA004856" Supported Approved "Focal adhesion sites,Cytosol" NA NA 2000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 7: Adipose tissue - Mixed function" "Cluster 27: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" 8 "Focal adhesion sites, Cytosol" "CAB002499: AB_563594, HPA004856: AB_1846316" "unprognostic (4.03e-2)" "unprognostic (5.17e-3)" "unprognostic (1.22e-2)" "unprognostic (5.22e-2)" "unprognostic (1.33e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (2.08e-4)" "unprognostic (1.48e-2)" "unprognostic (6.95e-2)" "unprognostic (2.89e-1)" "prognostic unfavorable (5.07e-4)" "unprognostic (5.84e-2)" "unprognostic (2.67e-2)" "prognostic unfavorable (1.05e-6)" "unprognostic (2.61e-1)" "unprognostic (9.11e-2)" "unprognostic (8.07e-2)" ITGB1 "CD29, FNRB, GPIIA, MDF2, MSK12" ENSG00000150093 "Integrin subunit beta 1" P05556 10 32887273-33005792 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Host-virus interaction, Myogenesis" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ductal cells: 1089.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003434, HPA059297, HPA069003" Enhanced Supported "Endoplasmic reticulum,Plasma membrane,Focal adhesion sites" NA NA 270000000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 62: Connective tissue - ECM organization" "Cluster 47: Endothelial cells - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" 19 "Plasma membrane, Focal adhesion sites" "Endoplasmic reticulum" "CAB003434: AB_303570, HPA059297: AB_2732634, HPA069003: AB_2732125" "unprognostic (3.07e-2)" "prognostic unfavorable (5.01e-4)" "unprognostic (8.67e-2)" "unprognostic (4.36e-1)" "unprognostic (1.20e-2)" "unprognostic (3.87e-2)" "unprognostic (1.60e-2)" "prognostic unfavorable (3.36e-6)" "unprognostic (3.22e-1)" "unprognostic (2.36e-3)" "unprognostic (3.68e-3)" "unprognostic (2.42e-1)" "unprognostic (1.02e-3)" "unprognostic (1.25e-2)" "unprognostic (2.23e-1)" "unprognostic (2.48e-1)" "unprognostic (3.08e-2)" ITGB4 CD104 ENSG00000132470 "Integrin subunit beta 4" P16144 17 75721328-75757818 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 194.7;skin 1: 199.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 161.2;Gastric mucus-secreting cells: 164.5;Mucus glandular cells: 163.8;Salivary duct cells: 287.3;Schwann cells: 164.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 49.5" "CAB002422, CAB005258, HPA036348, HPA036349" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA 980000 "Cluster 30: Non-specific - DNA binding" "Cluster 48: Stomach - Proteolysis" "Cluster 39: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 6 "Plasma membrane, Cell Junctions" "CAB002422: AB_563480, CAB005258: AB_2129021, HPA036348: AB_2675077, HPA036349: AB_2675078" "unprognostic (3.17e-3)" "unprognostic (3.52e-1)" "unprognostic (4.19e-1)" "unprognostic (2.27e-1)" "unprognostic (5.75e-2)" "unprognostic (6.11e-3)" "unprognostic (1.28e-1)" "prognostic unfavorable (7.18e-4)" "unprognostic (1.05e-1)" "unprognostic (4.14e-2)" "prognostic unfavorable (6.39e-4)" "unprognostic (1.02e-1)" "unprognostic (2.23e-2)" "unprognostic (1.65e-2)" "unprognostic (1.05e-1)" "unprognostic (1.07e-1)" "unprognostic (1.43e-1)" ITGB6 ENSG00000115221 "Integrin subunit beta 6" P18564 2 160099667-160200313 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Amelogenesis imperfecta, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 66.2;skeletal muscle: 77.1;tongue: 62.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 82.9;Alveolar cells type 2: 105.6;Basal respiratory cells: 118.7;Collecting duct cells: 72.0;Ductal cells: 59.4;Exocrine glandular cells: 104.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Pancreas - Ductal cells, Prostate - Urothelial cells, Skeletal muscle - Skeletal myocytes, Stomach - Gastric mucous cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA023626, CAB073536" Approved Approved "Nucleoplasm,Cell Junctions,Centrosome" NA NA "Cluster 19: Non-specific - Basic cellular processes" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 1 "Nucleoplasm, Cell Junctions" Centrosome "CAB073536: , HPA023626: AB_2671267" "unprognostic (1.27e-1)" "unprognostic (1.57e-2)" "unprognostic (6.90e-2)" "unprognostic (8.22e-3)" "unprognostic (3.61e-3)" "unprognostic (1.50e-2)" "unprognostic (1.72e-3)" "unprognostic (2.04e-2)" "unprognostic (1.72e-1)" "unprognostic (7.06e-2)" "prognostic unfavorable (5.03e-6)" "unprognostic (1.04e-1)" "unprognostic (2.73e-1)" "unprognostic (4.97e-2)" "unprognostic (1.23e-1)" "unprognostic (2.16e-1)" "unprognostic (1.00e-1)" JPT1 "ARM2, HN1, HN1A" ENSG00000189159 "Jupiter microtubule associated homolog 1" Q9UK76 17 75135248-75168281 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 395.6" "Cell type enhanced" "Detected in all" "Early spermatids: 1422.5;Extravillous trophoblasts: 1662.9;Late spermatids: 1349.4;monocytes: 1049.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 773.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011097, HPA059729" Approved Supported "Microtubules,Cytokinetic bridge,Cytosol" Yes NA 40000 "Cluster 7: Non-specific - Innate immune response" "Cluster 4: Testis - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 45: Non-specific - Mixed function" 5 Cytosol "Microtubules, Cytokinetic bridge" "HPA011097: , HPA059729: AB_2684114" "unprognostic (1.13e-2)" "unprognostic (1.81e-1)" "unprognostic (1.31e-3)" "unprognostic (3.57e-3)" "unprognostic (6.71e-2)" "unprognostic (2.51e-3)" "prognostic unfavorable (1.58e-7)" "unprognostic (3.58e-2)" "unprognostic (1.37e-1)" "prognostic favorable (4.91e-4)" "unprognostic (1.25e-3)" "unprognostic (8.24e-2)" "prognostic unfavorable (1.77e-7)" "unprognostic (1.83e-1)" "unprognostic (8.99e-2)" "unprognostic (4.84e-2)" "unprognostic (1.51e-1)" KHNYN KIAA0323 ENSG00000100441 "KH and NYN domain containing" O15037 14 24429286-24441843 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003402 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 45: Non-specific - Mixed function" 4 Nucleoplasm Cytosol "HPA003402: AB_1079190" "unprognostic (2.95e-1)" "prognostic unfavorable (4.38e-4)" "unprognostic (1.03e-1)" "unprognostic (8.03e-2)" "prognostic unfavorable (5.10e-4)" "unprognostic (4.11e-2)" "unprognostic (1.65e-1)" "unprognostic (2.01e-1)" "unprognostic (1.28e-1)" "unprognostic (1.05e-2)" "unprognostic (5.75e-2)" "unprognostic (1.88e-1)" "unprognostic (1.47e-1)" "unprognostic (8.43e-2)" "unprognostic (1.41e-1)" "unprognostic (6.08e-2)" "unprognostic (2.73e-1)" KLK10 "NES1, PRSSL1" ENSG00000129451 "Kallikrein related peptidase 10" O43240 19 51012739-51020175 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Cell cycle" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 108.7;esophagus: 400.9;vagina: 184.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 75.8;Basal respiratory cells: 62.0;Club cells: 92.0;Ionocytes: 71.8;Mucus glandular cells: 62.4;Secretory cells: 79.4;Suprabasal keratinocytes: 140.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 97.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 80.0;pancreatic cancer: 79.5" "Adipose visceral - Mesothelial cells, Prostate - Prostate basal glandular cells" "Region enriched" "Detected in single" 4 "hippocampal formation: 1.6" "Not detected" "Not detected" "Secreted in other tissues" Enzyme NA NA 2500000 "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" "prognostic favorable (8.32e-4)" "unprognostic (6.06e-2)" "unprognostic (1.73e-1)" "unprognostic (4.26e-3)" "unprognostic (3.81e-2)" "unprognostic (1.80e-1)" "unprognostic (1.51e-2)" "unprognostic (2.10e-2)" "unprognostic (3.94e-1)" "unprognostic (3.38e-2)" "prognostic unfavorable (6.46e-5)" "unprognostic (2.71e-2)" "unprognostic (2.46e-6)" "unprognostic (9.34e-2)" "unprognostic (7.81e-2)" "unprognostic (2.66e-3)" "unprognostic (1.52e-2)" KRT18 ENSG00000111057 "Keratin 18" P05783 12 52948871-52952906 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Host-virus interaction" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 3815.2;Distal enterocytes: 4172.9;Ductal cells: 5450.8;Extravillous trophoblasts: 6192.8;Syncytiotrophoblasts: 8413.7" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 5 "choroid plexus: 72.5;hypothalamus: 28.1;medulla oblongata: 35.3;pons: 63.2" "Immune cell enriched" "Detected in many" 7 "basophil: 76.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 76.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 15.6" "CAB000008, CAB000030, HPA001605" Enhanced Supported Cytosol NA NA 140000000 "Cluster 46: Basophils - Proteolysis" "Cluster 45: Intestine - Digestion" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 26 Cytosol "CAB000008: , CAB000030: , HPA001605: AB_2666381" "unprognostic (1.98e-1)" "unprognostic (1.03e-1)" "unprognostic (3.31e-1)" "unprognostic (1.63e-2)" "unprognostic (1.25e-1)" "unprognostic (7.26e-3)" "unprognostic (4.09e-3)" "prognostic unfavorable (5.06e-4)" "unprognostic (8.81e-2)" "unprognostic (4.17e-1)" "prognostic unfavorable (1.78e-4)" "unprognostic (3.05e-1)" "unprognostic (1.04e-1)" "unprognostic (1.27e-1)" "unprognostic (2.19e-1)" "unprognostic (1.11e-2)" "unprognostic (1.13e-2)" KRT19 "CK19, K19, K1CS, MGC15366" ENSG00000171345 "Keratin 19" P08727 17 41523617-41528308 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 864.1;salivary gland: 786.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 6850.6;Club cells: 5440.4;Distal enterocytes: 7654.8;Extravillous trophoblasts: 8032.7;Proximal enterocytes: 8878.0" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 13.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 4070.4" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Region enriched" "Detected in many" 7 "spinal cord: 62.5" "CAB000031, HPA002465" Enhanced Supported "Intermediate filaments" NA NA 300000000 "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 35: Non-specific - DNA binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 65 "Intermediate filaments" "CAB000031: AB_2234418, HPA002465: AB_1079179" "unprognostic (1.09e-1)" "unprognostic (1.83e-1)" "unprognostic (3.86e-2)" "unprognostic (1.59e-2)" "unprognostic (2.24e-2)" "unprognostic (1.13e-1)" "unprognostic (2.29e-1)" "unprognostic (2.80e-2)" "unprognostic (3.14e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (6.82e-5)" "unprognostic (1.90e-2)" "prognostic unfavorable (2.98e-5)" "unprognostic (3.52e-2)" "unprognostic (2.14e-1)" "unprognostic (3.08e-2)" "unprognostic (2.35e-2)" KRT7 "CK-7, CK7, K2C7, K7, SCL" ENSG00000135480 "Keratin 7" P08729 12 52232520-52252186 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 856.8;thyroid gland: 420.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 8394.3;Alveolar cells type 2: 2030.6;Ductal cells: 2259.6;Extravillous trophoblasts: 4906.6;Mucus glandular cells: 2614.0;Pancreatic endocrine cells: 2519.8" "Cancer enhanced" "Detected in many" "urothelial cancer: 560.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Liver - Cholangiocyte, Pancreas - Ductal cells, Skin - Eccrine sweat gland cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000028, HPA007272, HPA007315, CAB079970, CAB080115" Enhanced Supported "Intermediate filaments,Cytosol" NA NA 1300000000 "Cluster 38: Salivary gland - Salivary secretion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 2 "Intermediate filaments, Cytosol" "CAB000028: AB_2134589, CAB079970: , CAB080115: , HPA007272: AB_1079181, HPA007315: " "unprognostic (2.71e-3)" "unprognostic (3.09e-1)" "unprognostic (2.20e-1)" "prognostic unfavorable (1.99e-4)" "unprognostic (2.22e-2)" "unprognostic (8.59e-2)" "unprognostic (1.27e-1)" "unprognostic (5.44e-3)" "unprognostic (2.74e-1)" "prognostic unfavorable (9.42e-5)" "prognostic unfavorable (7.78e-5)" "unprognostic (4.54e-2)" "prognostic favorable (2.77e-9)" "unprognostic (2.82e-1)" "unprognostic (1.43e-2)" "unprognostic (3.28e-1)" "unprognostic (3.98e-3)" KRT75 K6HF ENSG00000170454 "Keratin 75" O95678 12 52424070-52434371 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "skin 1: 26.6" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 3.0;Basal respiratory cells: 1.3;Late spermatids: 3.8;Pancreatic endocrine cells: 5.1;Serous glandular cells: 2.2;Suprabasal keratinocytes: 4.7" "Cancer enriched" "Detected in many" 4 "head and neck cancer: 36.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 7.4" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA019367, HPA076201" Enhanced Approved "Plasma membrane,Cytosol" NA NA 1500000000 "Cluster 13: Skin - Cornification" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 103 Cytosol "Plasma membrane" "HPA019367: AB_1852239, HPA076201: AB_2686786" "unprognostic (2.83e-2)" "unprognostic (2.81e-2)" "unprognostic (1.65e-2)" "unprognostic (5.79e-2)" "unprognostic (8.85e-3)" "unprognostic (2.67e-1)" "unprognostic (2.17e-2)" "unprognostic (1.72e-1)" "unprognostic (6.60e-2)" "unprognostic (9.20e-2)" "unprognostic (5.19e-2)" "unprognostic (2.45e-1)" "unprognostic (8.98e-2)" "unprognostic (1.94e-1)" KRT80 KB20 ENSG00000167767 "Keratin 80" Q6KB66 12 52168996-52192014 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skin 1: 212.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 94.1;Ductal cells: 52.9;Glandular and luminal cells: 33.0;Mucus glandular cells: 45.8;Pancreatic endocrine cells: 32.3;Suprabasal keratinocytes: 33.5;Syncytiotrophoblasts: 52.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Liver - Cholangiocyte, Pancreas - Ductal cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA077836, HPA077918" Enhanced "Intermediate filaments" No No 230000000 "Cluster 13: Skin - Cornification" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 3 "Intermediate filaments" "HPA077836: AB_2686857, HPA077918: AB_2686871" "prognostic unfavorable (1.05e-4)" "unprognostic (5.45e-3)" "unprognostic (5.35e-2)" "unprognostic (9.19e-3)" "unprognostic (2.85e-4)" "unprognostic (6.68e-2)" "unprognostic (2.06e-3)" "unprognostic (1.26e-3)" "unprognostic (5.60e-2)" "unprognostic (4.06e-2)" "unprognostic (7.06e-3)" "unprognostic (1.02e-1)" "unprognostic (8.79e-3)" "unprognostic (8.85e-2)" "unprognostic (2.03e-1)" "unprognostic (1.51e-1)" "unprognostic (2.98e-2)" KRT81 "Hb-1, KRTHB1" ENSG00000205426 "Keratin 81" Q14533 12 52285913-52291534 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 46 "skin 1: 140.1" "Group enriched" "Detected in some" 5 "Breast glandular cells: 39.7;Pancreatic endocrine cells: 101.9" "Cancer enhanced" "Detected in many" "breast cancer: 46.1;cervical cancer: 49.2" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 49 "basophil: 171.6" "Lineage enriched" "Detected in many" 49 "granulocytes: 171.6" "Cancer enhanced" "Detected in many" "breast cancer: 443.2" HPA049778 Supported NA NA 130000000 "Cluster 46: Basophils - Proteolysis" "Cluster 82: Skin - Keratinization" "Cluster 1: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 45: Non-specific - Mixed function" 22 "HPA049778: AB_2680877" "unprognostic (1.69e-2)" "unprognostic (5.61e-2)" "unprognostic (6.57e-2)" "unprognostic (2.90e-1)" "unprognostic (5.64e-2)" "unprognostic (1.77e-1)" "unprognostic (2.00e-1)" "unprognostic (3.64e-3)" "unprognostic (1.87e-1)" "unprognostic (5.10e-2)" "unprognostic (4.89e-2)" "unprognostic (2.21e-1)" "unprognostic (2.64e-4)" "unprognostic (5.98e-2)" "unprognostic (1.86e-1)" "unprognostic (2.25e-1)" "unprognostic (7.31e-2)" KRTAP1-1 "HB2A, KAP1.1, KAP1.1A, KAP1.1B" ENSG00000188581 "Keratin associated protein 1-1" Q07627 17 41040541-41041450 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 328 "skin 1: 78.8" "Cell type enriched" "Detected in single" 7 "Ductal cells: 6.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells" NA NA "Cluster 82: Skin - Keratinization" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 45: Non-specific - Mixed function" 150 "unprognostic (2.90e-1)" KRTAP2-3 KAP2.3 ENSG00000212724 "Keratin associated protein 2-3" P0C7H8 17 41059240-41060114 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 103 "skin 1: 20.0" "Group enriched" "Detected in some" 6 "Ductal cells: 21.0;Glandular and luminal cells: 34.2;Pancreatic endocrine cells: 44.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Hair cortex cells" HPA059203 Supported NA NA "Cluster 82: Skin - Keratinization" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Non-specific - Mixed function" 9 "HPA059203: AB_2683947" "unprognostic (2.22e-1)" "unprognostic (2.58e-2)" "unprognostic (3.79e-3)" "unprognostic (3.25e-3)" "unprognostic (2.78e-2)" "unprognostic (6.91e-2)" "unprognostic (1.38e-1)" "unprognostic (6.41e-4)" "unprognostic (7.83e-6)" "unprognostic (1.71e-1)" "unprognostic (9.36e-2)" LAMA3 "BM600-150kDa, epiligrin, kalinin-165kDa, LAMNA, nicein-150kDa" ENSG00000053747 "Laminin subunit alpha 3" Q16787 18 23689453-23956222 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 128.1;Basal respiratory cells: 105.5;Distal enterocytes: 104.5;Gastric mucus-secreting cells: 122.0;Paneth cells: 84.4;Salivary duct cells: 74.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 40.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 161.4" "Kidney - Endothelial cells, Lung - Alveolar cells type 1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA009309, CAB010757" Uncertain Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" "Cell adhesion" NA NA 1800000 "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" "Endoplasmic reticulum" "CAB010757: AB_477162, HPA009309: AB_1079224" "unprognostic (1.49e-2)" "unprognostic (2.14e-2)" "unprognostic (6.36e-2)" "unprognostic (3.82e-3)" "unprognostic (2.08e-1)" "unprognostic (1.11e-1)" "unprognostic (1.83e-1)" "unprognostic (2.28e-3)" "unprognostic (1.59e-1)" "unprognostic (7.09e-3)" "prognostic unfavorable (3.58e-6)" "unprognostic (1.98e-1)" "unprognostic (2.36e-1)" "unprognostic (3.15e-1)" "unprognostic (9.91e-3)" "unprognostic (3.98e-2)" "unprognostic (1.13e-1)" LAMB3 "BM600-125kDa, kalinin-140kDa, LAMNB1, nicein-125kDa" ENSG00000196878 "Laminin subunit beta 3" Q13751 1 209614870-209652425 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Amelogenesis imperfecta, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 71.3;urinary bladder: 70.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 215.0;Basal respiratory cells: 405.4;Ductal cells: 165.9;Gastric mucus-secreting cells: 175.7;Ionocytes: 178.6;Salivary duct cells: 225.6" "Cancer enhanced" "Detected in all" "head and neck cancer: 223.9" "Region enriched" "Detected in many" 7 "cerebral cortex: 41.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 438.1" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Breast myoepithelial cells, Colon - Colon enterocytes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA007584, HPA008069, CAB078183" Enhanced Approved Vesicles "Secreted to extracellular matrix" "Cell adhesion" NA NA 20000 "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" Vesicles "CAB078183: AB_2665825, HPA007584: , HPA008069: AB_1079228" "prognostic favorable (8.43e-4)" "unprognostic (3.08e-2)" "unprognostic (1.46e-2)" "unprognostic (2.88e-2)" "unprognostic (8.00e-2)" "unprognostic (1.60e-3)" "unprognostic (1.75e-1)" "prognostic unfavorable (9.62e-5)" "unprognostic (1.95e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (2.55e-4)" "unprognostic (1.31e-1)" "prognostic unfavorable (2.43e-5)" "unprognostic (1.02e-1)" "unprognostic (2.38e-1)" "unprognostic (6.01e-2)" "unprognostic (4.92e-3)" LAMC2 "BM600-100kDa, EBR2, EBR2A, kalinin-105kDa, LAMB2T, LAMNB2, nicein-100kDa" ENSG00000058085 "Laminin subunit gamma 2" Q13753 1 183186238-183245127 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 37.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 120.9;Basal respiratory cells: 202.4;Basal squamous epithelial cells: 151.8;Ductal cells: 154.8;Pancreatic endocrine cells: 161.3;Secretory cells: 97.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 231.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 511.2" "Breast - Breast myoepithelial cells, Liver - Cholangiocyte, Pancreas - Ductal cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004257, HPA024638, HPA046539, HPA046540, CAB078165" Enhanced Approved "Endoplasmic reticulum,Golgi apparatus" "Secreted to extracellular matrix" "Cell adhesion" No No 130000 "Cluster 45: Intestine - Digestion" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" "Endoplasmic reticulum, Golgi apparatus" "CAB004257: AB_627873, CAB078165: AB_2665800, HPA024638: AB_1852689, HPA046539: , HPA046540: " "unprognostic (7.27e-3)" "unprognostic (7.21e-3)" "unprognostic (3.24e-1)" "unprognostic (6.20e-3)" "unprognostic (9.43e-2)" "unprognostic (4.94e-3)" "unprognostic (4.12e-2)" "prognostic unfavorable (4.20e-6)" "unprognostic (1.25e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (7.11e-5)" "unprognostic (2.77e-1)" "unprognostic (7.24e-2)" "unprognostic (1.47e-1)" "unprognostic (2.18e-1)" "unprognostic (3.18e-1)" "unprognostic (1.26e-1)" LCN2 "24p3, NGAL" ENSG00000148346 "Lipocalin 2" P80188 9 128149071-128153453 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Apoptosis, Immunity, Innate immunity, Ion transport, Iron transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 2741.6;gallbladder: 2147.7;salivary gland: 1269.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 4540.1;Club cells: 6415.0;Ductal cells: 6544.0;Exocrine glandular cells: 2381.1;Ionocytes: 7173.7;Mucus glandular cells: 2129.9" "Cancer enhanced" "Detected in many" "stomach cancer: 944.6" "Region enriched" "Detected in single" 5 "choroid plexus: 4.2" "Group enriched" "Detected in some" 88 "basophil: 9.7;neutrophil: 11.9;non-classical monocyte: 4.7" "Group enriched" "Detected in many" 84 "granulocytes: 11.9;monocytes: 4.7" "Cancer enhanced" "Detected in many" "Bile duct cancer: 2754.0;pancreatic cancer: 1459.4" "Colon - Colon enterocytes, Prostate - Urothelial cells" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 6 "cerebellum: 275.8;spinal cord: 180.6" "HPA002695, CAB016549, CAB016550" Enhanced Supported "Endoplasmic reticulum" "Secreted in other tissues" Transport NA NA 297000000 590000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 47 "Endoplasmic reticulum" "CAB016549: , CAB016550: , HPA002695: AB_1852758" "prognostic favorable (9.61e-4)" "unprognostic (1.71e-1)" "unprognostic (2.59e-1)" "unprognostic (7.38e-3)" "unprognostic (1.01e-2)" "unprognostic (4.66e-2)" "unprognostic (1.86e-1)" "unprognostic (1.01e-1)" "unprognostic (4.33e-1)" "unprognostic (1.79e-1)" "unprognostic (2.36e-2)" "unprognostic (2.83e-2)" "unprognostic (1.10e-3)" "unprognostic (6.15e-2)" "unprognostic (2.37e-1)" "unprognostic (3.15e-2)" "unprognostic (1.11e-2)" LDHA ENSG00000134333 "Lactate dehydrogenase A" P00338 11 18394560-18408425 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Cancer-related genes, Disease variant, FDA approved drug targets, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 1895.3;Extravillous trophoblasts: 2258.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015336, CAB069404" Uncertain Supported Vesicles,Cytosol NA NA 170000000 "Cluster 33: Non-specific - ATP binding" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" 2 Cytosol Vesicles "CAB015336: AB_2134947, CAB069404: " "unprognostic (8.83e-2)" "prognostic unfavorable (2.78e-5)" "unprognostic (3.81e-2)" "unprognostic (1.73e-1)" "unprognostic (3.43e-3)" "unprognostic (4.66e-3)" "prognostic unfavorable (3.26e-8)" "prognostic unfavorable (2.27e-6)" "unprognostic (1.08e-1)" "unprognostic (1.88e-2)" "prognostic unfavorable (8.09e-6)" "unprognostic (1.76e-2)" "prognostic unfavorable (9.69e-9)" "unprognostic (4.15e-2)" "unprognostic (1.89e-1)" "unprognostic (3.07e-1)" "unprognostic (1.05e-2)" LHB "CGB4, hLHB, LSH-B" ENSG00000104826 "Luteinizing hormone subunit beta" P01229 19 49015980-49017091 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" Hormone "Cancer-related genes, Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 249 "pituitary gland: 4374.0" "Cell type enhanced" "Detected in some" "Early spermatids: 4.7;Late spermatids: 4.7;Melanocytes: 3.4;Oocytes: 3.7;Syncytiotrophoblasts: 10.2" "Cancer enhanced" "Detected in many" "melanoma: 2.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Exocrine glandular cells" "CAB022241, CAB022707, HPA038925" Enhanced "Secreted to blood" Hormone NA NA "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Non-specific - Mixed function" 2 "CAB022241: , CAB022707: , HPA038925: AB_2676272" "unprognostic (8.12e-2)" "unprognostic (3.59e-1)" "unprognostic (2.34e-3)" "unprognostic (1.41e-2)" "unprognostic (8.89e-2)" "unprognostic (6.25e-2)" "unprognostic (3.90e-3)" "unprognostic (5.69e-2)" "unprognostic (7.04e-2)" "unprognostic (6.06e-2)" "prognostic unfavorable (6.78e-4)" "unprognostic (2.47e-2)" "unprognostic (1.68e-3)" "unprognostic (1.38e-1)" "unprognostic (4.46e-1)" "unprognostic (9.52e-2)" "unprognostic (4.86e-2)" LLGL2 "HGL, Hugl-2" ENSG00000073350 "LLGL scribble cell polarity complex component 2" Q6P1M3 17 75525080-75575209 "Predicted intracellular proteins" "Cell cycle, Cell division, Exocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 221.5;Distal enterocytes: 256.3;Gastric mucus-secreting cells: 143.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 3.1" "Group enriched" "Detected in many" 6 "dendritic cells: 1.1;NK-cells: 2.1;T-cells: 3.1" "Low cancer specificity" "Detected in all" "Colon - Colon enterocytes, Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" HPA022913 Uncertain Supported Vesicles,Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 48: Stomach - Proteolysis" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 45: Non-specific - Mixed function" 3 Cytosol Vesicles "HPA022913: AB_1852930" "unprognostic (1.18e-1)" "unprognostic (4.18e-2)" "unprognostic (2.89e-2)" "unprognostic (1.34e-1)" "unprognostic (3.43e-1)" "prognostic favorable (9.25e-4)" "unprognostic (2.60e-2)" "unprognostic (2.40e-1)" "unprognostic (7.97e-2)" "unprognostic (3.49e-1)" "prognostic favorable (6.00e-5)" "unprognostic (6.22e-3)" "prognostic favorable (6.14e-9)" "unprognostic (1.14e-2)" "unprognostic (2.77e-2)" "unprognostic (4.15e-3)" "unprognostic (1.56e-2)" LMTK3 "KIAA1883, LMR3, PPP1R101, TYKLM3" ENSG00000142235 "Lemur tyrosine kinase 3" Q96Q04 19 48485271-48513935 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.8" "Cell type enhanced" "Detected in many" "Club cells: 30.1;Excitatory neurons: 35.7;Inhibitory neurons: 37.2;Ionocytes: 28.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enteroendocrine cells, Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040203, HPA077070" Enhanced Supported Uncertain "Nucleoplasm,Cell Junctions" NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 45: Non-specific - Mixed function" 1 Nucleoplasm "Cell Junctions" "HPA040203: AB_10671690, HPA077070: AB_2732330" "unprognostic (2.41e-1)" "unprognostic (1.48e-1)" "unprognostic (5.37e-2)" "unprognostic (5.45e-2)" "unprognostic (2.95e-1)" "unprognostic (1.71e-2)" "unprognostic (5.67e-2)" "unprognostic (2.46e-1)" "unprognostic (2.09e-1)" "unprognostic (2.51e-3)" "unprognostic (5.71e-2)" "unprognostic (1.47e-1)" "prognostic favorable (3.18e-8)" "unprognostic (1.38e-1)" "unprognostic (3.22e-2)" "unprognostic (3.24e-1)" "unprognostic (6.11e-2)" LSR "ILDR3, LISCH7" ENSG00000105699 "Lipolysis stimulated lipoprotein receptor" Q86X29 19 35248330-35267964 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 141.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 209.3;Distal enterocytes: 256.9;Ductal cells: 236.0;Exocrine glandular cells: 243.4;Syncytiotrophoblasts: 248.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007270, HPA075309" Approved Enhanced "Plasma membrane,Cell Junctions" NA NA 3500000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 48: Stomach - Proteolysis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 2 "Plasma membrane, Cell Junctions" "HPA007270: AB_1079253, HPA075309: " "unprognostic (3.90e-1)" "unprognostic (1.12e-1)" "unprognostic (2.34e-2)" "unprognostic (2.67e-3)" "unprognostic (2.28e-2)" "unprognostic (6.07e-3)" "unprognostic (1.55e-1)" "unprognostic (9.84e-2)" "unprognostic (2.17e-1)" "unprognostic (2.70e-2)" "unprognostic (2.23e-2)" "unprognostic (3.42e-2)" "prognostic favorable (8.09e-4)" "unprognostic (1.64e-1)" "unprognostic (1.84e-1)" "unprognostic (2.99e-2)" "unprognostic (1.54e-2)" LYNX1-SLURP2 ENSG00000284505 "LYNX1-SLURP2 readthrough" 8 142764334-142778224 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "esophagus: 6.1;intestine: 6.8" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 1.2;Serous glandular cells: 2.2;Suprabasal keratinocytes: 3.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.4" "Lineage enriched" "Detected in single" 8 "monocytes: 1.4" "Low cancer specificity" "Detected in single" "Intracellular and membrane" NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 45: Non-specific - Mixed function" LYPLA2 APT-2 ENSG00000011009 "Lysophospholipase 2" O95372 1 23791145-23795539 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 181.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063151 Approved Nucleoplasm,Cytosol NA NA 110000 "Cluster 29: Non-specific - Unknown function" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 45: Non-specific - Mixed function" 1 "Nucleoplasm, Cytosol" "HPA063151: " "unprognostic (8.84e-2)" "unprognostic (6.87e-2)" "unprognostic (2.65e-1)" "unprognostic (7.81e-3)" "unprognostic (2.12e-2)" "unprognostic (2.22e-2)" "prognostic unfavorable (5.84e-5)" "unprognostic (3.06e-1)" "unprognostic (1.80e-1)" "unprognostic (5.18e-2)" "unprognostic (2.52e-1)" "unprognostic (2.40e-1)" "prognostic favorable (4.99e-4)" "unprognostic (6.10e-2)" "unprognostic (1.47e-1)" "unprognostic (1.71e-3)" "unprognostic (1.24e-1)" MACC1 "7A5, SH3BP4L" ENSG00000183742 "MET transcriptional regulator MACC1" Q6ZN28 7 20134655-20217404 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Growth factor, Mitogen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 11.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 114.7;Club cells: 62.7;Exocrine glandular cells: 63.1;Glandular and luminal cells: 64.7;Ionocytes: 76.9;Mucus glandular cells: 144.0;Salivary duct cells: 87.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Cholangiocyte, Pancreas - Ductal cells, Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA020081, HPA020103, HPA029476, CAB068194" Supported Approved Mitochondria NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" Mitochondria "CAB068194: AB_2665682, HPA020081: AB_1844386, HPA020103: AB_1844387, HPA029476: AB_10610136" "unprognostic (1.59e-2)" "unprognostic (1.88e-1)" "unprognostic (3.43e-2)" "prognostic unfavorable (1.56e-5)" "unprognostic (2.26e-1)" "unprognostic (1.42e-2)" "unprognostic (7.01e-2)" "unprognostic (2.52e-2)" "unprognostic (2.05e-1)" "unprognostic (2.43e-2)" "unprognostic (2.43e-3)" "unprognostic (1.03e-1)" "prognostic favorable (5.71e-9)" "unprognostic (4.49e-2)" "unprognostic (2.91e-1)" "unprognostic (1.78e-1)" "unprognostic (6.93e-3)" MALL BENE ENSG00000144063 "Mal, T cell differentiation protein like" Q13021 2 110083870-110116022 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 358.1;intestine: 228.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 185.3;Alveolar cells type 2: 238.9;Distal enterocytes: 653.1;Ductal cells: 277.7;Paneth cells: 207.2;Proximal enterocytes: 768.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 8.2;neutrophil: 2.4" "Lineage enriched" "Detected in many" 7 "granulocytes: 8.2" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051410 Uncertain NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 51 "HPA051410: AB_2681474" "unprognostic (5.17e-1)" "unprognostic (4.15e-2)" "unprognostic (2.92e-1)" "unprognostic (3.53e-1)" "unprognostic (1.92e-2)" "unprognostic (1.66e-1)" "unprognostic (2.22e-1)" "unprognostic (4.46e-2)" "unprognostic (6.50e-2)" "unprognostic (6.82e-2)" "prognostic unfavorable (1.23e-4)" "unprognostic (2.37e-1)" "unprognostic (7.27e-2)" "unprognostic (2.23e-1)" "unprognostic (2.84e-1)" "unprognostic (2.80e-1)" "unprognostic (6.50e-3)" MELTF "CD228, FLJ38863, MAP97, MFI2, MGC4856, MTf, MTF1" ENSG00000163975 Melanotransferrin P08582 3 196980590-197029835 "CD markers, Plasma proteins, Predicted intracellular proteins" "Ion transport, Iron transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 34.1;salivary gland: 69.2" "Cell type enhanced" "Detected in many" "Ductal cells: 28.1;granulocytes: 43.4;Mesothelial cells: 33.3;Serous glandular cells: 27.2" "Cancer enhanced" "Detected in all" "melanoma: 32.7" "Region enhanced" "Detected in all" "choroid plexus: 63.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "skin cancer: 190.5" "Skeletal muscle - Fibroblasts, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA004880 Approved "Intracellular and membrane" Transport NA NA 41000000 "Cluster 52: Kidney - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 45: Non-specific - Mixed function" 1 "HPA004880: AB_1853844" "unprognostic (8.68e-3)" "unprognostic (3.68e-2)" "unprognostic (1.75e-2)" "unprognostic (7.68e-3)" "unprognostic (1.06e-2)" "unprognostic (1.08e-2)" "unprognostic (5.53e-2)" "unprognostic (1.64e-3)" "unprognostic (1.20e-2)" "unprognostic (1.23e-1)" "unprognostic (3.68e-3)" "unprognostic (8.14e-2)" "prognostic unfavorable (6.99e-11)" "unprognostic (2.29e-1)" "unprognostic (2.11e-1)" "unprognostic (5.75e-2)" "unprognostic (2.09e-2)" MIA CD-RAP ENSG00000261857 "MIA SH3 domain containing" Q16674 19 40771648-40777490 "Cancer-related genes, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 56.0;pituitary gland: 74.2;salivary gland: 41.9;stomach 1: 64.0" "Group enriched" "Detected in some" 6 "Breast glandular cells: 43.9;Breast myoepithelial cells: 91.8;Melanocytes: 147.7;Schwann cells: 74.1" "Cancer enriched" "Detected in many" 5 "melanoma: 58.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "neutrophil: 2.7" "Lineage enriched" "Detected in single" 9 "granulocytes: 2.7" "Cancer enriched" "Detected in many" 5 "skin cancer: 473.9" "Colon - Enteric glia cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in single" 27 "olfactory bulb: 25.9" HPA042369 Approved "Secreted to blood" "Growth factor" NA NA 8270000 64000 "Cluster 35: Neutrophils - Protein binding" "Cluster 48: Stomach - Proteolysis" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 45: Non-specific - Mixed function" "HPA042369: AB_10794420" "prognostic favorable (2.08e-4)" "unprognostic (1.30e-1)" "unprognostic (3.15e-1)" "unprognostic (9.02e-3)" "unprognostic (2.27e-1)" "unprognostic (1.11e-1)" "unprognostic (6.37e-3)" "unprognostic (3.67e-2)" "unprognostic (1.61e-1)" "unprognostic (9.37e-2)" "unprognostic (1.17e-1)" "unprognostic (3.19e-1)" "unprognostic (3.29e-8)" "unprognostic (5.88e-2)" "unprognostic (2.44e-1)" "unprognostic (2.20e-1)" "unprognostic (2.56e-1)" MICA PERB11.1 ENSG00000204520 "MHC class I polypeptide-related sequence A" 6 31399784-31415315 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" NA NA "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 9: Non-specific - Receptor signaling" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Non-specific - Mixed function" "unprognostic (1.94e-1)" "prognostic unfavorable (5.88e-4)" "unprognostic (1.01e-1)" "unprognostic (6.55e-2)" "unprognostic (2.66e-2)" "unprognostic (6.10e-2)" "unprognostic (5.19e-2)" "unprognostic (4.09e-2)" "unprognostic (2.05e-1)" "unprognostic (1.18e-1)" "unprognostic (1.93e-1)" "unprognostic (1.13e-1)" "unprognostic (1.77e-1)" "unprognostic (1.23e-1)" "unprognostic (4.92e-2)" "unprognostic (2.18e-1)" "unprognostic (1.12e-2)" MIEF2 "MGC23130, MiD49, SMCR7" ENSG00000177427 "Mitochondrial elongation factor 2" Q96C03 17 18260597-18266552 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042334 Uncertain NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 79: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 42: Non-specific - Unknown function" "Cluster 45: Non-specific - Mixed function" 4 "HPA042334: AB_10794418" "unprognostic (1.42e-1)" "unprognostic (1.05e-1)" "unprognostic (1.39e-1)" "unprognostic (1.08e-1)" "unprognostic (2.46e-2)" "unprognostic (7.56e-3)" "unprognostic (1.30e-1)" "unprognostic (8.28e-2)" "unprognostic (2.34e-1)" "unprognostic (1.73e-1)" "unprognostic (1.28e-2)" "unprognostic (3.62e-2)" "prognostic favorable (1.75e-7)" "unprognostic (4.68e-2)" "unprognostic (1.39e-1)" "unprognostic (2.40e-2)" "unprognostic (3.06e-2)" MIEN1 "C17orf37, C35, MGC14832, ORB3, Rdx12, XTP4" ENSG00000141741 "Migration and invasion enhancer 1" Q9BRT3 17 39728496-39730532 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "breast cancer: 293.7" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056650, HPA061344" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 27: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 45: Non-specific - Mixed function" 9 "Plasma membrane, Cytosol" "HPA056650: , HPA061344: AB_2684484" "unprognostic (2.48e-1)" "unprognostic (3.18e-2)" "unprognostic (3.04e-1)" "unprognostic (1.13e-2)" "unprognostic (3.04e-1)" "unprognostic (1.17e-1)" "unprognostic (4.47e-2)" "unprognostic (8.37e-2)" "unprognostic (6.72e-2)" "unprognostic (2.03e-1)" "unprognostic (1.90e-1)" "unprognostic (3.17e-1)" "unprognostic (2.99e-2)" "unprognostic (3.70e-1)" "unprognostic (2.00e-1)" "unprognostic (3.88e-3)" "unprognostic (2.22e-3)" MMP1 CLG ENSG00000196611 "Matrix metallopeptidase 1" P03956 11 102789401-102798160 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Collagen degradation, Host-virus interaction" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 73.2;stomach 1: 46.2;urinary bladder: 50.4" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 77.3;Cholangiocytes: 32.4;Ductal cells: 114.5;Exocrine glandular cells: 87.0;Pancreatic endocrine cells: 83.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 344.2" "Region enriched" "Detected in single" 7 "cerebral cortex: 3.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 912.7;thyroid cancer: 1579.6" "Pancreas - Ductal cells" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "amygdala: 1.1;hippocampal formation: 4.0" HPA004920 Approved Vesicles "Secreted to extracellular matrix" Enzyme NA NA 7730000 55000 "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 12: Non-specific - Vasculature" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Non-specific - Mixed function" Vesicles "HPA004920: AB_2667293" "unprognostic (4.11e-3)" "prognostic unfavorable (4.66e-4)" "unprognostic (4.20e-3)" "unprognostic (1.19e-3)" "unprognostic (6.46e-2)" "unprognostic (6.50e-2)" "prognostic unfavorable (4.22e-6)" "unprognostic (7.83e-3)" "unprognostic (2.94e-2)" "unprognostic (5.44e-2)" "unprognostic (1.11e-3)" "unprognostic (1.75e-1)" "prognostic unfavorable (9.86e-10)" "unprognostic (1.67e-2)" "unprognostic (1.49e-1)" "unprognostic (1.26e-2)" "unprognostic (5.11e-2)" MMP14 MT1-MMP ENSG00000157227 "Matrix metallopeptidase 14" P50281 14 22836560-22849041 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 260.9;Pancreatic endocrine cells: 120.6" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "choroid plexus: 126.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009918, HPA051432" Approved Approved "Intermediate filaments,Cytosol" No No 1400000 "Cluster 62: Connective tissue - ECM organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Non-specific - Mixed function" 17 Cytosol "Intermediate filaments" "CAB009918: AB_2250767, HPA051432: AB_2681484" "unprognostic (1.34e-1)" "unprognostic (1.37e-1)" "unprognostic (1.11e-2)" "unprognostic (2.81e-1)" "unprognostic (4.28e-2)" "unprognostic (1.12e-2)" "unprognostic (3.05e-3)" "unprognostic (5.91e-3)" "unprognostic (1.95e-1)" "prognostic unfavorable (9.48e-4)" "unprognostic (3.82e-3)" "unprognostic (7.31e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (5.02e-2)" "unprognostic (6.69e-2)" "unprognostic (1.00e-2)" "unprognostic (3.41e-3)" MMP24OS MMP24-AS1 ENSG00000126005 "MMP24 opposite strand" A0A0U1RRL7 20 35201745-35278131 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 347.3;Proximal tubular cells: 380.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 62: Non-specific - Plasma proteins" "Cluster 45: Non-specific - Mixed function" "unprognostic (6.31e-2)" "unprognostic (4.34e-2)" "unprognostic (1.14e-1)" "unprognostic (4.42e-2)" "unprognostic (5.73e-3)" "unprognostic (2.10e-1)" "unprognostic (1.72e-1)" "unprognostic (4.34e-3)" "unprognostic (5.75e-2)" "unprognostic (4.33e-1)" "unprognostic (1.90e-2)" "unprognostic (1.38e-1)" "unprognostic (1.47e-3)" "unprognostic (4.57e-2)" "unprognostic (2.73e-1)" "unprognostic (6.64e-2)" "unprognostic (7.58e-2)" MMP3 "STMY, STMY1" ENSG00000149968 "Matrix metallopeptidase 3" P08254 11 102835801-102843609 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation, Immunity, Innate immunity" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 87.7;salivary gland: 277.6" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 19.9;Early spermatids: 31.2;Extravillous trophoblasts: 16.6;Fibroblasts: 51.3;Pancreatic endocrine cells: 17.0;Serous glandular cells: 11.0;Smooth muscle cells: 18.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 59.9" "Region enriched" "Detected in some" 5 "thalamus: 15.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 10 "Brain cancer: 71.9;Sarcoma: 120.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA007875 Uncertain Supported Vesicles "Secreted to extracellular matrix" Immunity NA NA 2540000 460000 "Cluster 38: Salivary gland - Salivary secretion" "Cluster 12: Non-specific - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 45: Non-specific - Mixed function" 1 Vesicles "HPA007875: AB_1079396" "unprognostic (2.27e-1)" "prognostic unfavorable (9.73e-4)" "unprognostic (1.63e-3)" "unprognostic (5.11e-3)" "unprognostic (3.78e-1)" "unprognostic (5.11e-2)" "unprognostic (5.26e-6)" "unprognostic (3.46e-2)" "unprognostic (7.14e-2)" "unprognostic (2.87e-1)" "prognostic unfavorable (4.09e-4)" "unprognostic (3.26e-2)" "unprognostic (1.22e-15)" "unprognostic (3.17e-1)" "unprognostic (1.55e-1)" "unprognostic (3.43e-2)" "unprognostic (2.34e-1)" MMP7 "MPSL1, PUMP-1" ENSG00000137673 "Matrix metallopeptidase 7" P09237 11 102520508-102530750 "Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 492.8;salivary gland: 260.0;urinary bladder: 203.4" "Group enriched" "Detected in many" 5 "Ductal cells: 7365.3;Pancreatic endocrine cells: 4761.1" "Cancer enhanced" "Detected in all" "pancreatic cancer: 352.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 627.7;Uterine cancer: 461.4" "Liver - Cholangiocyte, Pancreas - Ductal cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025869, HPA051358" Supported Approved Nucleoplasm,Vesicles,Cytosol "Secreted to extracellular matrix" Enzyme NA NA 2810000 35000 "Cluster 58: Placenta - Pregnancy" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" 1 "Nucleoplasm, Vesicles" Cytosol "CAB025869: , HPA051358: AB_2681452" "unprognostic (1.06e-3)" "unprognostic (9.51e-2)" "unprognostic (4.15e-2)" "unprognostic (1.38e-1)" "unprognostic (7.70e-3)" "unprognostic (7.28e-2)" "prognostic unfavorable (2.53e-4)" "prognostic unfavorable (3.38e-4)" "unprognostic (3.96e-2)" "unprognostic (5.63e-2)" "unprognostic (6.59e-3)" "unprognostic (1.51e-1)" "unprognostic (6.36e-3)" "unprognostic (1.42e-2)" "unprognostic (5.54e-2)" "unprognostic (1.48e-1)" "unprognostic (1.46e-1)" MRPS17 "HSPC011, MRP-S17, RPMS17" ENSG00000239789 "Mitochondrial ribosomal protein S17" Q9Y2R5 7 55951877-55956500 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047159 Approved NA NA "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 45: Non-specific - Mixed function" 3 "HPA047159: AB_2679961" "unprognostic (3.38e-1)" "unprognostic (2.71e-2)" "unprognostic (1.24e-1)" "unprognostic (8.61e-3)" "unprognostic (2.16e-2)" "unprognostic (1.94e-2)" "unprognostic (7.07e-3)" "unprognostic (1.80e-1)" "unprognostic (3.92e-1)" "unprognostic (2.86e-2)" "unprognostic (1.79e-2)" "unprognostic (1.47e-1)" "unprognostic (4.20e-3)" "unprognostic (7.17e-2)" "unprognostic (2.36e-2)" "unprognostic (2.24e-1)" "unprognostic (2.63e-1)" MSANTD3 "C9orf30, MGC17337" ENSG00000066697 "Myb/SANT DNA binding domain containing 3" Q96H12 9 100427143-100451734 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 53.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062662 Approved Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 23: Non-specific - Cellular respiration" "Cluster 37: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Non-specific - Mixed function" 3 Nucleoplasm "HPA062662: AB_2684826" "unprognostic (1.58e-1)" "unprognostic (1.96e-1)" "unprognostic (5.51e-2)" "unprognostic (1.51e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (6.66e-5)" "prognostic unfavorable (3.23e-6)" "prognostic unfavorable (3.56e-4)" "unprognostic (1.51e-1)" "unprognostic (2.61e-3)" "unprognostic (5.52e-2)" "unprognostic (3.38e-1)" "prognostic unfavorable (3.22e-7)" "unprognostic (1.95e-1)" "unprognostic (1.18e-1)" "unprognostic (2.28e-1)" "unprognostic (2.16e-2)" MSN ENSG00000147065 Moesin P26038 X 65588377-65741931 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 630.5;NK-cells: 340.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Lung - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000263, CAB010898, HPA011135, HPA011227, CAB047336, CAB047337, CAB047338" Enhanced Enhanced "Plasma membrane" NA NA 130000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 44: Non-specific - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 45: Non-specific - Mixed function" 4 "Plasma membrane" "CAB010898: AB_260635, CAB047336: , CAB047337: , CAB047338: , HPA000263: AB_1856043, HPA011135: AB_1854053, HPA011227: AB_1854054" "unprognostic (1.03e-1)" "unprognostic (7.89e-2)" "unprognostic (7.64e-2)" "unprognostic (5.38e-2)" "unprognostic (4.08e-3)" "unprognostic (3.51e-2)" "unprognostic (1.11e-2)" "unprognostic (1.44e-2)" "unprognostic (3.35e-2)" "unprognostic (1.70e-2)" "unprognostic (9.04e-3)" "unprognostic (1.32e-1)" "prognostic unfavorable (1.60e-5)" "unprognostic (5.68e-3)" "unprognostic (7.75e-2)" "unprognostic (7.21e-2)" "unprognostic (6.81e-2)" MTMR11 CRA ENSG00000014914 "Myotubularin related protein 11" A4FU01 1 149928651-149936879 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 25.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 119.3;Enteroendocrine cells: 44.2;Intestinal goblet cells: 100.3;Paneth cells: 77.1;Proximal enterocytes: 103.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.3;myeloid DC: 1.7;non-classical monocyte: 1.3" "Group enriched" "Detected in many" 16 "dendritic cells: 1.7;monocytes: 1.3" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030351, HPA072906" Enhanced Approved Centrosome NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 45: Intestine - Digestion" "Cluster 3: Choroid plexus - Cilium" "Cluster 5: Rhabdoid - Unknown function" "Cluster 45: Non-specific - Mixed function" Centrosome "HPA030351: AB_10602185, HPA072906: " "unprognostic (1.14e-1)" "unprognostic (3.01e-3)" "unprognostic (1.42e-1)" "unprognostic (1.22e-2)" "unprognostic (2.05e-1)" "unprognostic (1.73e-1)" "unprognostic (1.37e-2)" "unprognostic (5.81e-2)" "unprognostic (7.94e-2)" "unprognostic (2.98e-1)" "unprognostic (2.88e-2)" "unprognostic (1.22e-1)" "unprognostic (5.83e-2)" "unprognostic (1.83e-1)" "unprognostic (5.67e-2)" "unprognostic (1.80e-2)" "unprognostic (9.12e-2)" MUC1 "ADMCKD, ADMCKD1, Ca15-3, CD227, EMA, KL-6, MCD, MCKD, MCKD1, PEM, PUM" ENSG00000185499 "Mucin 1, cell surface associated" P15941 1 155185824-155192916 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 419.1;stomach 1: 862.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 963.7;Alveolar cells type 2: 1456.7;Exocrine glandular cells: 951.7;Gastric mucus-secreting cells: 572.5;Ionocytes: 447.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Lineage enhanced" "Detected in single" "T-cells: 1.2" "Cancer enhanced" "Detected in all" "breast cancer: 211.1;pancreatic cancer: 218.2" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Mitotic cells (Colon), Lung - Alveolar cells type 2, Skin - Sebaceous gland cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "CAB000036, CAB001986, HPA004179, HPA007235, HPA008855, CAB080102, CAB080103" Enhanced Supported "Plasma membrane" "Secreted in other tissues" "No annotated function" NA NA 4000000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 48: Stomach - Proteolysis" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 4 "Plasma membrane" "CAB000036: AB_2148557, CAB001986: , CAB080102: , CAB080103: , HPA004179: AB_1846282, HPA007235: AB_1846281, HPA008855: AB_1846283" "unprognostic (4.74e-2)" "unprognostic (2.84e-2)" "unprognostic (2.19e-1)" "unprognostic (8.01e-2)" "unprognostic (1.32e-2)" "unprognostic (1.70e-1)" "unprognostic (2.61e-3)" "unprognostic (6.34e-2)" "unprognostic (1.43e-1)" "unprognostic (3.23e-1)" "prognostic unfavorable (4.60e-4)" "unprognostic (4.75e-1)" "unprognostic (2.05e-2)" "unprognostic (1.13e-1)" "unprognostic (8.12e-2)" "unprognostic (1.42e-1)" "unprognostic (1.21e-1)" MYEOV OCIM ENSG00000172927 "Myeloma overexpressed" Q96EZ4 11 69294151-69341682 "Predicted membrane proteins" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 5.2;breast: 5.0;esophagus: 9.3;stomach 1: 5.9" "Cell type enhanced" "Detected in some" "Breast glandular cells: 36.0;Breast myoepithelial cells: 31.7;Club cells: 12.0;Ductal cells: 10.6;Early spermatids: 11.4;Gastric mucus-secreting cells: 20.6;Paneth cells: 19.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Prostate - Urothelial cells, Stomach - Gastric mucous cells, Testis - Late spermatids" HPA012949 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 45: Non-specific - Mixed function" 3 Nucleoplasm Vesicles "HPA012949: AB_1854241" "unprognostic (1.42e-2)" "unprognostic (8.56e-2)" "unprognostic (7.07e-2)" "unprognostic (3.36e-1)" "unprognostic (5.60e-2)" "unprognostic (7.28e-3)" "unprognostic (7.58e-3)" "prognostic unfavorable (2.00e-4)" "unprognostic (3.49e-1)" "unprognostic (6.33e-2)" "prognostic unfavorable (1.54e-7)" "unprognostic (2.83e-1)" "prognostic unfavorable (1.48e-5)" "unprognostic (2.08e-1)" "unprognostic (1.16e-1)" "unprognostic (3.35e-1)" "unprognostic (3.69e-2)" MYL12B MRLC2 ENSG00000118680 "Myosin light chain 12B" O14950 18 3261479-3278461 "Plasma proteins, Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039262, HPA045244, HPA059197" Supported NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 21: Non-specific - Metabolism" "Cluster 13: Non-specific - Mixed function" "Cluster 45: Non-specific - Mixed function" 1 "HPA039262: AB_2676418, HPA045244: AB_2679269, HPA059197: AB_2683944" "unprognostic (2.55e-2)" "unprognostic (7.31e-2)" "unprognostic (5.69e-2)" "unprognostic (4.05e-2)" "unprognostic (3.66e-1)" "unprognostic (2.85e-3)" "unprognostic (1.38e-2)" "unprognostic (7.65e-2)" "unprognostic (2.89e-2)" "unprognostic (1.27e-2)" "prognostic unfavorable (9.69e-4)" "unprognostic (1.18e-1)" "prognostic favorable (8.17e-5)" "unprognostic (3.38e-1)" "unprognostic (3.77e-1)" "prognostic favorable (6.62e-6)" "unprognostic (1.27e-2)" MYL6 "ESMLC, MLC1SM, MLC3NM" ENSG00000092841 "Myosin light chain 6" P60660 12 56158346-56163496 "Plasma proteins, Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "HPA046859, HPA063034" Approved NA NA 60000000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 44: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" 8 "HPA046859: AB_2679842, HPA063034: AB_2684927" "unprognostic (1.10e-1)" "unprognostic (4.99e-2)" "unprognostic (1.89e-1)" "unprognostic (3.86e-2)" "unprognostic (1.43e-1)" "unprognostic (1.89e-1)" "unprognostic (3.73e-2)" "unprognostic (3.53e-1)" "unprognostic (2.00e-1)" "unprognostic (3.51e-3)" "unprognostic (4.11e-2)" "unprognostic (2.04e-1)" "unprognostic (2.86e-2)" "unprognostic (8.33e-3)" "unprognostic (1.71e-1)" "unprognostic (7.90e-2)" "unprognostic (2.01e-1)" MYO6 "DFNA22, DFNB37, KIAA0389" ENSG00000196586 "Myosin VI" Q9UM54 6 75749201-75919537 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Endocytosis, Hearing, Protein transport, Transport" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Cardiomyopathy, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 271.6;Oligodendrocytes: 380.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 5.4;MAIT T-cell: 3.0;memory CD4 T-cell: 1.7;memory CD8 T-cell: 3.1;naive CD8 T-cell: 3.0;NK-cell: 2.9" "Group enriched" "Detected in many" 7 "NK-cells: 2.9;T-cells: 5.4" "Cancer enhanced" "Detected in all" "prostate cancer: 146.4" "Adipose visceral - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010762, HPA035482, HPA035483" Enhanced Supported Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 52: Kidney - Transmembrane transport" "Cluster 11: White matter - Signal transduction" "Cluster 11: Neuronal - Sensory perception" "Cluster 45: Non-specific - Mixed function" 3 Nucleoplasm "CAB010762: AB_477166, HPA035482: , HPA035483: AB_2674647" "unprognostic (6.29e-2)" "unprognostic (6.34e-2)" "unprognostic (3.63e-3)" "unprognostic (1.30e-1)" "unprognostic (8.98e-2)" "unprognostic (2.73e-2)" "unprognostic (3.41e-3)" "unprognostic (1.23e-2)" "unprognostic (1.23e-2)" "unprognostic (2.66e-2)" "unprognostic (7.78e-2)" "unprognostic (2.78e-2)" "prognostic favorable (1.27e-12)" "unprognostic (1.57e-1)" "unprognostic (1.72e-1)" "unprognostic (1.41e-1)" "unprognostic (2.49e-2)" MYRF "C11orf9, MRF, Ndt80, pqn-47" ENSG00000124920 "Myelin regulatory factor" Q9Y2G1 11 61752636-61788518 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding, Hydrolase, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 160.2;stomach 1: 85.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 78.8;Cholangiocytes: 51.5;Gastric mucus-secreting cells: 118.5;Mesothelial cells: 68.3;Oligodendrocytes: 238.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 52.9" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018310 Approved Nucleoplasm,Cytosol NA NA 1400000 "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Non-specific - Mixed function" Nucleoplasm Cytosol "HPA018310: AB_1845534" "unprognostic (3.51e-2)" "unprognostic (3.34e-1)" "unprognostic (1.56e-1)" "unprognostic (5.39e-2)" "unprognostic (1.54e-1)" "unprognostic (3.65e-2)" "unprognostic (1.34e-1)" "unprognostic (9.34e-3)" "unprognostic (2.44e-1)" "unprognostic (1.27e-1)" "unprognostic (1.01e-2)" "unprognostic (2.54e-2)" "prognostic unfavorable (2.01e-4)" "unprognostic (8.91e-3)" "unprognostic (1.11e-1)" "unprognostic (2.67e-1)" "unprognostic (6.73e-2)" NAPG ENSG00000134265 "NSF attachment protein gamma" Q99747 18 10525905-10552764 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008208, HPA011389" Enhanced Supported "Plasma membrane" NA NA 8800 "Cluster 45: Eosinophils - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 49: Hindbrain - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 45: Non-specific - Mixed function" "Plasma membrane" "HPA008208: AB_1854305, HPA011389: AB_1854306" "unprognostic (1.23e-1)" "unprognostic (7.64e-3)" "unprognostic (6.96e-2)" "unprognostic (1.53e-1)" "unprognostic (9.83e-2)" "unprognostic (2.28e-1)" "unprognostic (1.28e-1)" "unprognostic (4.59e-2)" "unprognostic (1.55e-2)" "unprognostic (2.77e-3)" "unprognostic (1.46e-3)" "unprognostic (5.85e-2)" "prognostic favorable (8.14e-4)" "unprognostic (3.81e-2)" "unprognostic (2.87e-1)" "unprognostic (4.97e-2)" "unprognostic (6.96e-2)" NCMAP "C1orf130, FLJ42528, MP11" ENSG00000184454 "Non-compact myelin associated protein" Q5T1S8 1 24556087-24609328 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "gallbladder: 7.1;pancreas: 8.3;salivary gland: 7.6" "Cell type enhanced" "Detected in many" "dendritic cells: 15.8;Ductal cells: 19.8;Exocrine glandular cells: 33.1;Schwann cells: 23.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 2.8" "Liver - Hepatocytes, Lung - Alveolar cells type 2, Pancreas - Ductal cells" "Low region specificity" "Detected in many" HPA013656 Uncertain NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 6: Non-specific - Immune response" "Cluster 20: Myeloma - Immune response" "Cluster 45: Non-specific - Mixed function" "HPA013656: AB_2275006" "unprognostic (3.38e-2)" "unprognostic (3.52e-2)" "unprognostic (2.79e-1)" "prognostic favorable (2.83e-6)" "unprognostic (3.26e-2)" "unprognostic (1.98e-1)" "unprognostic (1.48e-1)" "unprognostic (1.69e-1)" "unprognostic (4.14e-1)" "unprognostic (1.73e-1)" "unprognostic (2.41e-2)" "unprognostic (1.04e-1)" "unprognostic (3.28e-3)" "unprognostic (9.88e-2)" "unprognostic (9.53e-2)" "unprognostic (1.63e-2)" "unprognostic (7.27e-3)" NDUFV2 CI-24k ENSG00000178127 "NADH:ubiquinone oxidoreductase core subunit V2" P19404 18 9102630-9134345 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 585.8" "Cell type enhanced" "Detected in all" "Ductal cells: 325.5;Exocrine glandular cells: 346.3;Pancreatic endocrine cells: 320.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003404, HPA077896" Enhanced Approved Nucleoplasm,Mitochondria,Cytosol No No 7600 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 23: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 45: Non-specific - Mixed function" 59 Mitochondria "Nucleoplasm, Cytosol" "HPA003404: AB_1079466, HPA077896: AB_2686866" "unprognostic (1.18e-1)" "unprognostic (3.89e-2)" "unprognostic (2.89e-1)" "unprognostic (8.22e-2)" "unprognostic (1.32e-2)" "unprognostic (6.72e-3)" "unprognostic (1.36e-2)" "unprognostic (1.18e-1)" "unprognostic (6.72e-3)" "unprognostic (1.32e-3)" "unprognostic (2.39e-1)" "unprognostic (6.84e-2)" "unprognostic (1.70e-1)" "unprognostic (5.51e-2)" "unprognostic (1.31e-1)" "unprognostic (6.56e-2)" "unprognostic (1.95e-3)" NECTIN2 "CD112, HVEB, Nectin-2, PRR2, PVRL2, PVRR2" ENSG00000130202 "Nectin cell adhesion molecule 2" Q92692 19 44846175-44889223 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 251.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 10.4" "Lineage enhanced" "Detected in many" "granulocytes: 10.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Colon - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012759, CAB026138, HPA073459" Enhanced Approved "Nucleoli fibrillar center,Cell Junctions" NA Yes 5900000 "Cluster 19: Eosinophils - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 66: Non-specific - Mitochondria" "Cluster 45: Non-specific - Mixed function" 10 "Nucleoli fibrillar center, Cell Junctions" "CAB026138: , HPA012759: AB_1846227, HPA073459: " "unprognostic (3.30e-2)" "unprognostic (2.84e-1)" "unprognostic (1.07e-1)" "unprognostic (5.61e-3)" "unprognostic (7.45e-2)" "unprognostic (2.21e-1)" "unprognostic (1.66e-2)" "unprognostic (6.63e-2)" "unprognostic (2.85e-1)" "unprognostic (2.97e-1)" "unprognostic (6.93e-2)" "unprognostic (3.19e-1)" "unprognostic (1.60e-1)" "unprognostic (2.15e-1)" "unprognostic (1.61e-1)" "unprognostic (8.19e-2)" "unprognostic (2.05e-1)" NEURL3 "Lincr, LOC93082, RNF132" ENSG00000163121 "Neuralized E3 ubiquitin protein ligase 3" Q96EH8 2 96497646-96508109 "Enzymes, Predicted intracellular proteins" "Host-virus interaction, Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "kidney: 15.7;pancreas: 24.4;salivary gland: 29.4" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 21.7;Collecting duct cells: 25.3;Ductal cells: 114.0;Exocrine glandular cells: 37.6;Ionocytes: 26.9;Pancreatic endocrine cells: 23.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Uterine cancer: 8.6" "Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in some" "Not detected" "Not detected" NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" "unprognostic (4.97e-2)" "unprognostic (6.07e-2)" "unprognostic (7.22e-2)" "unprognostic (1.42e-2)" "unprognostic (2.49e-2)" "unprognostic (4.35e-2)" "prognostic unfavorable (6.46e-4)" "unprognostic (2.29e-1)" "unprognostic (9.55e-2)" "unprognostic (1.18e-2)" "unprognostic (1.06e-1)" "unprognostic (8.14e-3)" "unprognostic (1.23e-2)" "unprognostic (5.83e-2)" "unprognostic (6.57e-2)" "unprognostic (2.44e-1)" "unprognostic (6.57e-4)" NF2 "ACN, BANF, merlin, merlin-1, SCH" ENSG00000186575 "NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor" P35240 22 29603556-29698598 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Deafness, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 72.1;Late spermatids: 120.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003097, CAB005385" Supported Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" 28 "Plasma membrane" "Nucleoplasm, Cytosol" "CAB005385: AB_2298548, HPA003097: AB_1079473" "unprognostic (3.27e-1)" "unprognostic (1.34e-2)" "unprognostic (1.34e-1)" "unprognostic (1.76e-2)" "unprognostic (3.14e-1)" "unprognostic (1.62e-1)" "unprognostic (5.76e-3)" "unprognostic (1.61e-1)" "unprognostic (3.67e-2)" "unprognostic (2.16e-2)" "unprognostic (2.01e-3)" "unprognostic (4.66e-1)" "prognostic favorable (2.89e-5)" "unprognostic (7.73e-3)" "unprognostic (1.31e-1)" "unprognostic (2.24e-1)" "unprognostic (9.62e-2)" NPPB ENSG00000120937 "Natriuretic peptide B" P16860 1 11857464-11858945 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Hormone, Vasoactive, Vasodilator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 556 "heart muscle: 4968.9" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 360.4;Pancreatic endocrine cells: 331.1;Sertoli cells: 291.0" "Cancer enhanced" "Detected in some" "testis cancer: 2.2" "Region enriched" "Detected in some" 7 "basal ganglia: 6.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 79.4;testis cancer: 62.4" "Region enhanced" "Detected in single" "pons and medulla: 1.4" "Low region specificity" "Detected in all" HPA077324 Approved Vesicles,Cytosol "Secreted to blood" Hormone NA NA 9680 "Cluster 30: Heart muscle - Heart development" "Cluster 33: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Non-specific - Mixed function" 7 Vesicles Cytosol "HPA077324: " "unprognostic (3.87e-1)" "unprognostic (1.29e-2)" "unprognostic (2.49e-1)" "unprognostic (4.23e-1)" "unprognostic (3.28e-2)" NR5A2 "B1F2, FTF, FTZ-F1, FTZ-F1beta, hB1F, hB1F-2, LRH-1, LRH1" ENSG00000116833 "Nuclear receptor subfamily 5 group A member 2" O00482 1 200027614-200177420 "Nuclear receptors, Predicted intracellular proteins, Transcription factors, Transporters" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 17.3;liver: 37.4;pancreas: 59.2" "Cell type enhanced" "Detected in some" "Adipocytes: 23.6;Cholangiocytes: 22.9;Distal enterocytes: 39.3;Ductal cells: 44.1;Endothelial cells: 35.7;Exocrine glandular cells: 59.6;Hepatocytes: 34.2;Paneth cells: 27.7;Proximal enterocytes: 41.5;Undifferentiated cells: 25.2" "Cancer enhanced" "Detected in many" "liver cancer: 6.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.3" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.3" "Cancer enhanced" "Detected in many" "cervical cancer: 12.2" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells" "Region enhanced" "Detected in single" "hypothalamus: 1.2" "Low region specificity" "Detected in many" "HPA005455, HPA017067" Approved Uncertain "Nuclear speckles" NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 24: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 45: Non-specific - Mixed function" "Nuclear speckles" "HPA005455: AB_1078140, HPA017067: AB_1844767" "unprognostic (7.47e-2)" "unprognostic (1.43e-1)" "unprognostic (5.84e-2)" "unprognostic (1.56e-2)" "unprognostic (1.19e-2)" "unprognostic (6.63e-3)" "unprognostic (4.46e-2)" "unprognostic (3.78e-2)" "unprognostic (3.34e-1)" "unprognostic (8.50e-2)" "unprognostic (4.64e-2)" "unprognostic (1.44e-1)" "unprognostic (1.00e-7)" "unprognostic (5.48e-2)" "unprognostic (5.07e-2)" "unprognostic (9.23e-2)" "unprognostic (1.37e-1)" NRAS N-ras ENSG00000213281 "NRAS proto-oncogene, GTPase" P01111 1 114704469-114716771 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010157, HPA049830, HPA072761, CAB079912" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 27: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 45: Non-specific - Mixed function" 4 "Plasma membrane, Cytosol" "CAB010157: AB_632073, CAB079912: AB_2784586, HPA049830: AB_2680903, HPA072761: " "unprognostic (4.75e-2)" "unprognostic (2.81e-1)" "unprognostic (1.09e-3)" "unprognostic (2.11e-2)" "unprognostic (8.59e-3)" "unprognostic (1.14e-1)" "prognostic unfavorable (3.03e-7)" "unprognostic (7.76e-3)" "unprognostic (1.57e-2)" "unprognostic (1.01e-3)" "prognostic unfavorable (1.36e-4)" "unprognostic (6.60e-3)" "prognostic unfavorable (7.87e-4)" "unprognostic (2.68e-1)" "unprognostic (1.30e-1)" "unprognostic (1.16e-1)" "unprognostic (3.33e-2)" NRG4 HRG4 ENSG00000169752 "Neuregulin 4" Q8WWG1 15 75935969-76059795 "Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "retina: 4.2" "Cell type enhanced" "Detected in many" "Early spermatids: 18.6;Exocrine glandular cells: 22.4;Gastric mucus-secreting cells: 31.2;Oocytes: 27.9;Prostatic glandular cells: 15.6;Rod photoreceptor cells: 28.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Skeletal muscle - Skeletal myocytes, Stomach - Gastric mucous cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA010957 Uncertain "Secreted to digestive system" "Growth factor" NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 2: Neurons - Nucleosome" "Cluster 56: Non-specific - Sensory perception" "Cluster 45: Non-specific - Mixed function" 4 "HPA010957: AB_1079504" "unprognostic (1.25e-1)" "unprognostic (1.54e-2)" "unprognostic (3.94e-2)" "unprognostic (1.67e-2)" "unprognostic (5.66e-2)" "unprognostic (4.10e-2)" "unprognostic (1.12e-2)" "unprognostic (1.17e-2)" "unprognostic (2.81e-2)" "unprognostic (2.82e-5)" "unprognostic (1.91e-2)" "unprognostic (1.56e-2)" "unprognostic (6.90e-5)" "unprognostic (8.28e-2)" "unprognostic (7.45e-2)" "unprognostic (1.08e-2)" "unprognostic (2.06e-1)" NT5E "CALJA, CD73, eN, eNT, NT5" ENSG00000135318 "5'-nucleotidase ecto" P21589 6 85449584-85495791 "CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 108.6;retina: 91.5" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 62.3;Lymphatic endothelial cells: 88.9;Oligodendrocyte precursor cells: 57.5;Paneth cells: 56.8;Rod photoreceptor cells: 78.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 33.1;naive CD8 T-cell: 30.8" "Group enriched" "Detected in many" 41 "B-cells: 33.1;T-cells: 30.8" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 320.3" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017357 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" Enzyme NA NA 3000000 "Cluster 34: B-cells - Unknown function" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 44: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Non-specific - Mixed function" 1 "Plasma membrane" "Nucleoplasm, Cytosol" "HPA017357: AB_1846330" "unprognostic (1.92e-2)" "unprognostic (4.44e-3)" "unprognostic (1.54e-1)" "unprognostic (1.57e-3)" "unprognostic (9.33e-2)" "unprognostic (1.82e-3)" "unprognostic (1.20e-2)" "prognostic unfavorable (6.66e-4)" "unprognostic (5.45e-2)" "unprognostic (1.80e-1)" "prognostic unfavorable (1.32e-5)" "unprognostic (1.39e-1)" "unprognostic (3.11e-2)" "prognostic unfavorable (1.02e-4)" "unprognostic (3.49e-2)" "unprognostic (2.26e-1)" "unprognostic (2.78e-1)" OCIAD2 MGC45416 ENSG00000145247 "OCIA domain containing 2" Q56VL3 4 48885019-48906937 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 149.6" "Cell type enhanced" "Detected in many" "Pancreatic endocrine cells: 640.1;Proximal enterocytes: 708.4;Proximal tubular cells: 1226.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040979, HPA041090" Enhanced Enhanced Mitochondria No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 29: Forebrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" Mitochondria "HPA040979: AB_10795497, HPA041090: AB_10796236" "unprognostic (4.29e-1)" "unprognostic (2.69e-1)" "unprognostic (3.76e-2)" "prognostic favorable (7.37e-4)" "unprognostic (3.49e-2)" "unprognostic (1.66e-2)" "unprognostic (9.05e-2)" "unprognostic (1.23e-1)" "unprognostic (2.00e-1)" "prognostic favorable (6.56e-4)" "prognostic unfavorable (6.89e-4)" "unprognostic (1.38e-1)" "prognostic favorable (2.67e-5)" "unprognostic (1.10e-1)" "unprognostic (8.54e-2)" "unprognostic (8.24e-3)" "prognostic favorable (2.34e-4)" ODAPH "AI2A4, C4orf26, FLJ23657" ENSG00000174792 "Odontogenesis associated phosphoprotein" Q17RF5 4 75556048-75565871 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Amelogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "placenta: 5.7" "Cell type enhanced" "Detected in some" "Early spermatids: 4.5;Extravillous trophoblasts: 10.7;Plasma cells: 5.4;Syncytiotrophoblasts: 26.2" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.1;urothelial cancer: 0.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 34 "basophil: 10.7" "Lineage enriched" "Detected in single" 34 "granulocytes: 10.7" "Cancer enhanced" "Detected in many" "Bladder cancer: 8.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted in other tissues" "No annotated function" NA NA "Cluster 32: Basophils - Transcription" "Cluster 58: Placenta - Pregnancy" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 3 "unprognostic (1.13e-1)" "unprognostic (4.45e-3)" "unprognostic (3.78e-1)" "unprognostic (1.66e-1)" "unprognostic (6.12e-2)" "unprognostic (2.12e-2)" "unprognostic (1.75e-2)" "unprognostic (2.44e-1)" "unprognostic (3.87e-2)" "unprognostic (5.30e-2)" "unprognostic (3.43e-1)" "unprognostic (1.17e-7)" "unprognostic (8.31e-2)" "unprognostic (2.70e-2)" "unprognostic (8.40e-4)" "unprognostic (6.53e-3)" ORMDL2 "adoplin-2, HSPC160, MST095, MSTP095" ENSG00000123353 "ORMDL sphingolipid biosynthesis regulator 2" Q53FV1 12 55818041-55821879 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065643 Supported "Endoplasmic reticulum" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 45: Non-specific - Mixed function" 18 "Endoplasmic reticulum" "HPA065643: AB_2685525" "unprognostic (1.12e-1)" "unprognostic (2.59e-2)" "unprognostic (2.41e-1)" "prognostic favorable (3.30e-5)" "unprognostic (6.92e-2)" "unprognostic (1.52e-3)" "prognostic unfavorable (9.75e-4)" "unprognostic (1.45e-2)" "unprognostic (1.11e-1)" "unprognostic (2.88e-2)" "unprognostic (1.84e-3)" "unprognostic (1.49e-1)" "unprognostic (2.75e-3)" "unprognostic (1.25e-1)" "unprognostic (2.20e-1)" "unprognostic (3.04e-2)" "unprognostic (5.68e-2)" PCDHB13 PCDH-BETA13 ENSG00000187372 "Protocadherin beta 13" Q9Y5F0 5 141213919-141218979 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cholangiocytes: 3.8;Melanocytes: 3.4;Mucus glandular cells: 6.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 2.9" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 64: Neuronal - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" "unprognostic (9.91e-3)" "unprognostic (3.34e-2)" "unprognostic (8.89e-2)" "unprognostic (2.06e-3)" "unprognostic (2.06e-1)" "unprognostic (1.29e-1)" "unprognostic (9.59e-2)" "unprognostic (3.55e-2)" "unprognostic (6.06e-2)" "unprognostic (2.61e-3)" "unprognostic (3.07e-1)" "unprognostic (1.13e-1)" "unprognostic (4.49e-2)" "unprognostic (2.80e-2)" "unprognostic (3.99e-2)" "unprognostic (8.19e-2)" "unprognostic (6.93e-3)" PDX1 "GSF, IDX-1, IPF1, IUF-1, MODY4, PDX-1, STF-1" ENSG00000139515 "Pancreatic and duodenal homeobox 1" P52945 13 27920000-27926313 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 40.6;pancreas: 13.0" "Cell type enhanced" "Detected in some" "Cholangiocytes: 13.4;Ductal cells: 16.1;Enteroendocrine cells: 7.4;Exocrine glandular cells: 6.4;Gastric mucus-secreting cells: 4.7;Pancreatic endocrine cells: 20.4" "Group enriched" "Detected in many" 4 "colorectal cancer: 8.4;pancreatic cancer: 8.6;stomach cancer: 7.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 6.2;Gastric cancer: 6.1" "Colon - Colon enterocytes" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025873, HPA059146" Enhanced Supported Nucleoplasm NA NA "Cluster 45: Intestine - Digestion" "Cluster 59: Leukemia - T-cell receptor" "Cluster 45: Non-specific - Mixed function" Nucleoplasm "CAB025873: , HPA059146: AB_2683927" "unprognostic (2.79e-2)" "unprognostic (2.22e-1)" "unprognostic (1.92e-1)" "unprognostic (2.65e-1)" "unprognostic (6.84e-2)" "unprognostic (3.89e-2)" "unprognostic (6.75e-3)" "unprognostic (7.10e-3)" "unprognostic (3.83e-2)" "unprognostic (1.65e-1)" "unprognostic (1.04e-1)" PET100 C19orf79 ENSG00000229833 "PET100 cytochrome c oxidase chaperone" P0DJ07 19 7629788-7631956 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 230.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067288 Approved Mitochondria NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 35: Non-specific - Mitochondria" "Cluster 21: Non-specific - Metabolism" "Cluster 23: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" Mitochondria "HPA067288: AB_2732762" "unprognostic (7.02e-2)" "prognostic favorable (6.81e-4)" "unprognostic (1.57e-1)" "unprognostic (9.87e-3)" "unprognostic (2.14e-1)" "unprognostic (4.18e-2)" "unprognostic (1.70e-1)" "prognostic favorable (7.97e-4)" "unprognostic (4.89e-1)" "unprognostic (2.88e-3)" "unprognostic (2.49e-2)" "unprognostic (2.33e-2)" "unprognostic (4.09e-2)" "unprognostic (1.37e-1)" "unprognostic (1.25e-1)" "unprognostic (2.66e-2)" "prognostic favorable (2.44e-4)" PGA4 ENSG00000229183 "Pepsinogen A4" P0DJD7 11 61222347-61231694 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1277 "stomach 1: 64644.4" "Group enriched" "Detected in some" 12 "Exocrine glandular cells: 38.9;Gastric mucus-secreting cells: 17.1" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "classical monocyte: 9.9;intermediate monocyte: 10.8;non-classical monocyte: 3.4" "Lineage enriched" "Detected in single" 26 "monocytes: 10.8" "Not detected" "Not detected" "Stomach - Chief cells" HPA046875 Supported "Secreted to digestive system" Enzyme NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 48: Stomach - Proteolysis" "Cluster 49: HMC-1 - Innate immune response" "Cluster 45: Non-specific - Mixed function" 8 "HPA046875: AB_2679851" "unprognostic (2.22e-1)" PGA5 ENSG00000256713 "Pepsinogen A5" P0DJD9 11 61241175-61251444 "Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Aspartyl protease, Hydrolase, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 2028 "stomach 1: 38780.0" "Cell type enriched" "Detected in some" 22 "Exocrine glandular cells: 1696.1" "Cancer enriched" "Detected in some" 12 "stomach cancer: 15.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 29 "classical monocyte: 1.8;intermediate monocyte: 4.3;non-classical monocyte: 2.4" "Lineage enriched" "Detected in single" 44 "monocytes: 4.3" "Not detected" "Not detected" "Breast - Adipocytes (Breast), Stomach - Chief cells" HPA046875 Supported "Secreted to digestive system" Enzyme NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 48: Stomach - Proteolysis" "Cluster 51: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 45: Non-specific - Mixed function" "HPA046875: AB_2679851" "unprognostic (1.36e-3)" "unprognostic (2.98e-2)" "unprognostic (5.83e-3)" "unprognostic (2.11e-1)" "unprognostic (4.22e-1)" "unprognostic (4.36e-2)" "unprognostic (2.16e-2)" "unprognostic (1.05e-1)" "unprognostic (7.10e-2)" PGAM1 "PGAM-B, PGAMA" ENSG00000171314 "Phosphoglycerate mutase 1" P18669 10 97426191-97433444 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis "Hydrolase, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 585.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells" "Low region specificity" "Detected in all" "HPA042528, HPA060483" Approved Supported Nucleoplasm NA NA 120000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 17: Neuronal - Synaptic function" "Cluster 1: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" 3 Nucleoplasm "HPA042528: AB_2678039, HPA060483: AB_2684292" "prognostic unfavorable (2.04e-4)" "prognostic unfavorable (3.86e-4)" "unprognostic (3.64e-1)" "unprognostic (5.64e-2)" "unprognostic (1.16e-1)" "unprognostic (9.47e-3)" "unprognostic (7.60e-3)" "unprognostic (1.74e-3)" "unprognostic (3.22e-1)" "unprognostic (1.05e-1)" "unprognostic (4.37e-3)" "unprognostic (2.48e-2)" "unprognostic (1.48e-1)" "unprognostic (5.74e-2)" "unprognostic (4.94e-2)" "unprognostic (1.19e-1)" "unprognostic (2.61e-3)" PGK1 ENSG00000102144 "Phosphoglycerate kinase 1" P00558 X 77910739-78129295 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis "Kinase, Transferase" "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 1039.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010065, HPA045385, HPA073644, HPA073656" Approved NA NA 170000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 35: Non-specific - Mitochondria" "Cluster 45: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" 4 "CAB010065: AB_628116, HPA045385: AB_2679306, HPA073644: AB_2732231, HPA073656: AB_2732235" "prognostic unfavorable (7.05e-8)" "prognostic unfavorable (2.69e-5)" "unprognostic (1.21e-1)" "unprognostic (8.30e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (2.65e-6)" "prognostic unfavorable (2.74e-4)" "unprognostic (1.13e-2)" "unprognostic (1.27e-1)" "unprognostic (6.66e-2)" "prognostic unfavorable (8.34e-4)" "unprognostic (5.66e-2)" "unprognostic (2.99e-1)" "unprognostic (8.99e-3)" "unprognostic (3.58e-1)" "unprognostic (2.90e-2)" "unprognostic (6.57e-2)" PGM2L1 "BM32A, FLJ32029" ENSG00000165434 "Phosphoglucomutase 2 like 1" Q6PCE3 11 74330316-74398433 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Isomerase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 87.1;Exocrine glandular cells: 112.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Liver - Vascular Endothelial cells, Skin - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056995, HPA060948" Enhanced Approved Mitochondria No No 140000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Non-specific - Mixed function" Mitochondria "HPA056995: AB_2683305, HPA060948: AB_2684394" "unprognostic (7.44e-3)" "unprognostic (1.33e-1)" "unprognostic (7.28e-3)" "unprognostic (8.91e-2)" "unprognostic (6.16e-2)" "unprognostic (1.55e-1)" "unprognostic (7.16e-6)" "unprognostic (1.43e-1)" "unprognostic (1.95e-1)" "unprognostic (5.97e-3)" "unprognostic (1.70e-2)" "unprognostic (2.98e-1)" "unprognostic (9.33e-3)" "unprognostic (3.71e-1)" "unprognostic (1.97e-1)" "unprognostic (3.04e-1)" "unprognostic (1.03e-2)" PHETA1 "FAM109A, FLJ32356, IPIP27A, SES1" ENSG00000198324 "PH domain containing endocytic trafficking adaptor 1" Q8N4B1 12 111360651-111369121 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 41.8;Proximal enterocytes: 50.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 3.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 48: Stomach - Proteolysis" "Cluster 19: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Non-specific - Mixed function" 1 "unprognostic (2.26e-1)" "unprognostic (6.88e-2)" "unprognostic (1.66e-1)" "unprognostic (1.05e-1)" "unprognostic (6.02e-2)" "unprognostic (1.15e-3)" "unprognostic (6.18e-3)" "unprognostic (1.11e-1)" "unprognostic (4.00e-2)" "unprognostic (5.51e-2)" "unprognostic (9.42e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (1.15e-4)" "unprognostic (1.95e-1)" "unprognostic (1.31e-1)" "unprognostic (4.90e-2)" "unprognostic (2.80e-3)" PIP4K2C "FLJ22055, PIP5K2C" ENSG00000166908 "Phosphatidylinositol-5-phosphate 4-kinase type 2 gamma" Q8TBX8 12 57591174-57603418 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 52.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028658 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" Cytosol "Nucleoplasm, Plasma membrane" "HPA028658: AB_10601245" "unprognostic (7.84e-3)" "unprognostic (1.51e-1)" "unprognostic (2.42e-1)" "unprognostic (2.77e-2)" "unprognostic (2.49e-2)" "unprognostic (3.37e-2)" "prognostic unfavorable (7.98e-4)" "unprognostic (3.17e-2)" "unprognostic (6.00e-2)" "unprognostic (5.51e-2)" "unprognostic (1.75e-1)" "unprognostic (1.88e-1)" "prognostic favorable (2.06e-6)" "unprognostic (1.87e-1)" "unprognostic (2.16e-1)" "unprognostic (3.27e-1)" "unprognostic (3.42e-1)" PKM "OIP3, PK3, PKM2, THBP1" ENSG00000067225 "Pyruvate kinase M1/2" P14618 15 72199029-72231819 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glycolysis, Translation regulation" "Allosteric enzyme, Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 3889.6;tongue: 2564.9" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 1894.9;Cone photoreceptor cells: 1779.0;Extravillous trophoblasts: 1559.9;Late spermatids: 1768.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019421, HPA029501" Uncertain Enhanced Cytosol No No 310000000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 45: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" 11 Cytosol "CAB019421: AB_2252325, HPA029501: AB_10602118" "unprognostic (8.73e-3)" "unprognostic (4.63e-3)" "unprognostic (1.68e-2)" "unprognostic (3.09e-1)" "unprognostic (6.51e-2)" "prognostic unfavorable (1.30e-4)" "prognostic unfavorable (2.74e-6)" "prognostic unfavorable (2.85e-4)" "unprognostic (9.51e-2)" "unprognostic (1.17e-2)" "prognostic unfavorable (5.17e-5)" "unprognostic (3.16e-1)" "unprognostic (3.22e-1)" "unprognostic (7.85e-2)" "unprognostic (3.17e-2)" "unprognostic (1.44e-1)" "unprognostic (1.25e-2)" PLA2G2F ENSG00000158786 "Phospholipase A2 group IIF" Q9BZM2 1 20139323-20150381 "Enzymes, Metabolic proteins, Predicted membrane proteins, RAS pathway related proteins" "Immunity, Innate immunity, Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 25 "lymphoid tissue: 7.8;skin 1: 14.4;urinary bladder: 11.4" "Cell type enhanced" "Detected in some" "Club cells: 2.0;Collecting duct cells: 1.9" "Cancer enriched" "Detected in some" 18 "urothelial cancer: 17.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Bladder cancer: 6.8" "Region enriched" "Detected in single" 4 "hippocampal formation: 3.0" "Not detected" "Not detected" "Intracellular and membrane" Immunity NA NA "Cluster 13: Skin - Cornification" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" "unprognostic (1.95e-1)" "unprognostic (1.18e-1)" "unprognostic (2.64e-2)" "unprognostic (1.79e-2)" "unprognostic (5.11e-2)" "unprognostic (4.63e-2)" "unprognostic (4.83e-2)" "unprognostic (1.51e-1)" "unprognostic (1.61e-2)" "unprognostic (3.36e-5)" "unprognostic (7.06e-2)" "unprognostic (1.84e-1)" "unprognostic (4.69e-1)" "prognostic favorable (3.86e-4)" PLAU "UPA, URK" ENSG00000122861 "Plasminogen activator, urokinase" P00749 10 73909177-73917496 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis, Plasminogen activation" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 101.0;urinary bladder: 123.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 212.1;Collecting duct cells: 89.5;Ionocytes: 129.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "myeloid DC: 1.1;neutrophil: 2.1;plasmacytoid DC: 2.0" "Group enriched" "Detected in many" 11 "dendritic cells: 2.0;granulocytes: 2.1" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 1199.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA070796 Supported Approved "Golgi apparatus,Vesicles" "Secreted to blood" "Blood coagulation" NA NA 647000 88000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 7: Adipose tissue - Mixed function" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 2 "Golgi apparatus, Vesicles" "HPA070796: " "unprognostic (1.96e-2)" "unprognostic (2.99e-2)" "unprognostic (7.40e-2)" "prognostic favorable (3.38e-4)" "unprognostic (4.73e-2)" "prognostic unfavorable (2.70e-4)" "unprognostic (1.39e-2)" "prognostic unfavorable (4.04e-4)" "unprognostic (2.26e-1)" "unprognostic (6.58e-2)" "prognostic unfavorable (1.32e-4)" "unprognostic (1.61e-1)" "prognostic unfavorable (3.51e-4)" "unprognostic (2.83e-1)" "unprognostic (3.37e-2)" "unprognostic (1.51e-2)" "unprognostic (1.77e-2)" PLEK2 ENSG00000100558 "Pleckstrin 2" Q9NYT0 14 67386984-67412167 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 49.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 90.2;Basal respiratory cells: 60.5;Intestinal goblet cells: 57.5;Langerhans cells: 66.3;Proximal enterocytes: 49.1;Suprabasal keratinocytes: 58.3;Undifferentiated cells: 54.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 6 "memory CD4 T-cell: 2.0;naive CD4 T-cell: 3.1" "Lineage enriched" "Detected in single" 7 "T-cells: 3.1" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Leydig cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA001208 Enhanced Uncertain Vesicles,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 53: Non-specific - Glycosylation" "Cluster 15: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 45: Non-specific - Mixed function" Vesicles Cytosol "HPA001208: AB_1079631" "unprognostic (4.41e-3)" "unprognostic (3.77e-1)" "unprognostic (1.15e-1)" "unprognostic (6.23e-2)" "unprognostic (6.88e-2)" "unprognostic (3.17e-3)" "unprognostic (1.18e-2)" "prognostic unfavorable (1.58e-4)" "unprognostic (1.97e-1)" "unprognostic (9.21e-3)" "prognostic unfavorable (8.26e-5)" "unprognostic (1.06e-1)" "unprognostic (3.09e-3)" "unprognostic (2.90e-1)" "unprognostic (1.29e-1)" "unprognostic (8.98e-2)" "unprognostic (4.59e-2)" PLP2 "A4, A4-LSB, MGC126187" ENSG00000102007 "Proteolipid protein 2" Q04941 X 49171898-49175235 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 509.1;Suprabasal keratinocytes: 542.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042415 Approved NA NA 250000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 12: Non-specific - Vasculature" "Cluster 36: Non-specific - mRNA processing" "Cluster 45: Non-specific - Mixed function" 58 "HPA042415: AB_10796907" "unprognostic (1.40e-1)" "unprognostic (6.67e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (3.32e-5)" "unprognostic (3.79e-2)" "unprognostic (1.30e-1)" "unprognostic (1.04e-3)" "unprognostic (4.14e-2)" "unprognostic (2.58e-2)" "unprognostic (9.99e-2)" "unprognostic (1.19e-2)" "unprognostic (1.66e-1)" "prognostic unfavorable (5.55e-10)" "unprognostic (1.66e-1)" "unprognostic (1.25e-1)" "unprognostic (1.29e-2)" "unprognostic (2.30e-1)" PMEPA1 "STAG1, TMEPAI" ENSG00000124225 "Prostate transmembrane protein, androgen induced 1" Q969W9 20 57648392-57711536 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Signal transduction inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 106.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 287.9;dendritic cells: 258.7;Ductal cells: 322.4;Muller glia cells: 312.7;Prostatic glandular cells: 636.7" "Cancer enhanced" "Detected in all" "prostate cancer: 157.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "naive B-cell: 6.3;plasmacytoid DC: 23.9" "Group enriched" "Detected in many" 8 "B-cells: 6.3;dendritic cells: 23.9" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Colon - Enteric glia cells, Prostate - Prostate glandular cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072291 Supported Vesicles "Intracellular and membrane" Other NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 34: Non-specific - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" Vesicles "HPA072291: AB_2686509" "unprognostic (2.72e-3)" "prognostic unfavorable (2.45e-4)" "unprognostic (5.77e-2)" "unprognostic (1.73e-1)" "unprognostic (6.61e-2)" "unprognostic (2.11e-3)" "unprognostic (3.13e-2)" "prognostic unfavorable (4.73e-5)" "unprognostic (5.53e-1)" "unprognostic (1.32e-3)" "unprognostic (7.83e-3)" "unprognostic (2.02e-1)" "prognostic unfavorable (2.87e-7)" "unprognostic (1.16e-1)" "unprognostic (2.35e-1)" "unprognostic (9.87e-3)" "prognostic unfavorable (7.60e-4)" POMGNT1 "FLJ20277, LGMD2O, MEB, MGAT1.2" ENSG00000085998 "Protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)" Q8WZA1 1 46188683-46220305 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044518 Approved NA NA 17000000 "Cluster 25: Non-specific - Unknown function" "Cluster 23: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 45: Non-specific - Mixed function" 6 "HPA044518: AB_10795985" "unprognostic (4.59e-3)" "unprognostic (1.59e-1)" "unprognostic (2.13e-1)" "unprognostic (1.80e-1)" "unprognostic (2.24e-1)" "unprognostic (3.20e-1)" "prognostic unfavorable (3.52e-4)" "unprognostic (1.82e-1)" "unprognostic (5.74e-2)" "unprognostic (5.37e-2)" "prognostic favorable (4.27e-4)" "unprognostic (5.86e-2)" "unprognostic (4.39e-2)" "unprognostic (4.99e-3)" "unprognostic (1.72e-1)" "unprognostic (2.16e-2)" "unprognostic (2.36e-1)" POU2F3 "Epoc-1, OCT11, PLA-1, Skn-1a" ENSG00000137709 "POU class 2 homeobox 3" Q9UKI9 11 120236640-120319945 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 46.3" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 12.2;Basal prostatic cells: 14.2;Collecting duct cells: 9.7;Gastric mucus-secreting cells: 9.4;Ionocytes: 10.7;Suprabasal keratinocytes: 23.5;Syncytiotrophoblasts: 11.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 3.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 5.3" "Lung - Alveolar cells type 2, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA019652, HPA073468" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 13: Skin - Cornification" "Cluster 48: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 45: Non-specific - Mixed function" Nucleoplasm "Plasma membrane, Cytosol" "HPA019652: AB_1855585, HPA073468: " "unprognostic (1.75e-1)" "unprognostic (2.12e-2)" "unprognostic (6.37e-2)" "unprognostic (2.41e-4)" "unprognostic (2.60e-1)" "unprognostic (4.46e-3)" "unprognostic (8.56e-3)" "unprognostic (9.34e-2)" "unprognostic (3.45e-2)" "unprognostic (1.12e-1)" "unprognostic (1.40e-3)" "unprognostic (2.08e-1)" "unprognostic (1.27e-2)" "unprognostic (9.69e-3)" "unprognostic (1.70e-1)" "prognostic favorable (8.14e-4)" "unprognostic (1.45e-1)" POU4F3 "BRN3C, DFNA15, DFNA42, DFNA52" ENSG00000091010 "POU class 4 homeobox 3" Q15319 5 146338839-146341728 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "urothelial cancer: 0.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 31 "lung cancer: 6.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA038215 Uncertain Supported Nucleoplasm NA NA "Cluster 46: Brainstem - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 45: Non-specific - Mixed function" 5 Nucleoplasm "HPA038215: AB_10697245" "unprognostic (8.41e-3)" "unprognostic (9.46e-2)" "unprognostic (1.84e-1)" "unprognostic (6.26e-4)" "unprognostic (1.86e-1)" "unprognostic (1.12e-1)" "unprognostic (1.03e-1)" "unprognostic (9.54e-2)" "unprognostic (1.61e-1)" "unprognostic (2.09e-3)" "unprognostic (1.20e-3)" "unprognostic (1.24e-3)" "unprognostic (1.38e-1)" "unprognostic (1.87e-1)" "unprognostic (8.84e-2)" "unprognostic (7.82e-2)" PPARD "FAAR, NR1C2, NUC1, NUCII, PPARB" ENSG00000112033 "Peroxisome proliferator activated receptor delta" Q03181 6 35342558-35428191 "FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 56.4;Syncytiotrophoblasts: 98.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB017635 Approved NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 80: Non-specific - Endocytosis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 1 "CAB017635: AB_1128605" "unprognostic (3.70e-2)" "unprognostic (8.75e-2)" "unprognostic (1.00e-1)" "unprognostic (1.89e-1)" "unprognostic (1.57e-1)" "unprognostic (8.68e-2)" "prognostic unfavorable (4.57e-4)" "unprognostic (4.59e-3)" "unprognostic (4.34e-1)" "unprognostic (1.45e-1)" "unprognostic (1.05e-1)" "unprognostic (1.51e-3)" "unprognostic (7.27e-3)" "unprognostic (1.43e-1)" "unprognostic (9.42e-2)" "unprognostic (5.95e-2)" "unprognostic (2.00e-2)" PPP1CA "PP-1A, PP1A, PP1alpha, PPP1A" ENSG00000172531 "Protein phosphatase 1 catalytic subunit alpha" P62136 11 67398181-67421183 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Cell cycle, Cell division, Glycogen metabolism, Host-virus interaction" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 559.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004545, HPA046833" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 3600000 "Cluster 25: Non-specific - Unknown function" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 27: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 45: Non-specific - Mixed function" 87 "Nucleoplasm, Plasma membrane, Cytosol" "CAB004545: AB_628177, HPA046833: AB_2679829" "unprognostic (1.03e-1)" "unprognostic (5.82e-3)" "unprognostic (1.10e-1)" "unprognostic (2.67e-1)" "unprognostic (2.09e-1)" "unprognostic (1.51e-2)" "unprognostic (3.15e-3)" "unprognostic (3.93e-2)" "unprognostic (2.07e-1)" "unprognostic (3.89e-2)" "unprognostic (5.05e-3)" "unprognostic (8.00e-2)" "unprognostic (1.66e-1)" "unprognostic (9.96e-2)" "unprognostic (7.69e-2)" "prognostic favorable (1.17e-4)" "unprognostic (7.60e-2)" PPP4C "PP4, PPX" ENSG00000149923 "Protein phosphatase 4 catalytic subunit" P60510 16 30075978-30085376 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 444.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043837 Supported Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 4: Testis - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" 12 Nucleoplasm "Plasma membrane, Cytosol" "HPA043837: AB_2678695" "unprognostic (1.20e-1)" "unprognostic (1.33e-2)" "unprognostic (2.68e-1)" "unprognostic (4.74e-2)" "unprognostic (2.16e-1)" "unprognostic (5.79e-3)" "unprognostic (3.28e-3)" "unprognostic (2.60e-3)" "unprognostic (3.82e-1)" "unprognostic (1.29e-1)" "unprognostic (2.52e-1)" "unprognostic (3.17e-2)" "unprognostic (1.98e-2)" "unprognostic (3.78e-2)" "unprognostic (9.36e-2)" "unprognostic (9.96e-2)" "unprognostic (1.88e-1)" PRELID1 "CGI-106, PRELI, PX19" ENSG00000169230 "PRELI domain containing 1" Q9Y255 5 177303799-177306949 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 935.3;Syncytiotrophoblasts: 947.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005701 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 48: Stomach - Proteolysis" "Cluster 45: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 45: Non-specific - Mixed function" Mitochondria Nucleoplasm "HPA005701: AB_1079721" "unprognostic (1.27e-1)" "unprognostic (8.99e-2)" "unprognostic (3.18e-2)" "unprognostic (2.09e-3)" "unprognostic (2.19e-1)" "unprognostic (8.07e-2)" "prognostic unfavorable (5.46e-5)" "unprognostic (7.63e-3)" "unprognostic (1.49e-1)" "unprognostic (8.90e-3)" "unprognostic (1.71e-1)" "unprognostic (6.97e-2)" "prognostic unfavorable (2.89e-7)" "unprognostic (3.59e-2)" "unprognostic (1.15e-1)" "unprognostic (1.89e-1)" "unprognostic (2.21e-1)" PRMT5 "HRMT1L5, SKB1, SKB1Hs" ENSG00000100462 "Protein arginine methyltransferase 5" O14744 14 22920525-22929408 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 72.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005525, CAB012459, HPA064708" Approved Supported Nucleoplasm,Cytosol NA NA 45000 "Cluster 13: Non-specific - Mitochondria" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 45: Non-specific - Mixed function" 51 "Nucleoplasm, Cytosol" "CAB012459: , HPA005525: AB_1079679, HPA064708: AB_2685330" "unprognostic (8.34e-2)" "unprognostic (5.14e-3)" "unprognostic (1.19e-2)" "unprognostic (2.19e-1)" "unprognostic (4.56e-3)" "prognostic unfavorable (1.82e-4)" "prognostic unfavorable (4.77e-5)" "unprognostic (3.64e-2)" "unprognostic (6.80e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (2.61e-4)" "unprognostic (4.69e-2)" "unprognostic (1.99e-3)" "unprognostic (1.21e-1)" "unprognostic (7.04e-2)" "unprognostic (6.28e-2)" "prognostic unfavorable (1.04e-4)" PRMT7 "FLJ10640, KIAA1933" ENSG00000132600 "Protein arginine methyltransferase 7" Q9NVM4 16 68310951-68360852 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Differentiation, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044241 Supported Enhanced "Nucleoplasm,Nucleoli fibrillar center" No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 79: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 45: Non-specific - Mixed function" 4 Nucleoplasm "Nucleoli fibrillar center" "HPA044241: AB_2678869" "unprognostic (9.33e-2)" "unprognostic (5.33e-2)" "unprognostic (1.52e-1)" "prognostic favorable (2.31e-5)" "unprognostic (2.92e-2)" "unprognostic (1.95e-1)" "unprognostic (4.12e-2)" "unprognostic (1.22e-1)" "unprognostic (3.74e-1)" "unprognostic (1.19e-1)" "unprognostic (4.74e-3)" "unprognostic (3.09e-2)" "unprognostic (7.72e-2)" "unprognostic (1.75e-1)" "unprognostic (9.23e-2)" "unprognostic (3.57e-1)" "unprognostic (1.31e-1)" PRRG2 PRGP2 ENSG00000126460 "Proline rich and Gla domain 2" O14669 19 49580646-49591004 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 27.4" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 42.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010702 Approved Approved Nucleoplasm,Nucleoli,Cytosol No NA "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 25: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 2 "Nucleoplasm, Nucleoli" Cytosol "HPA010702: AB_1079693" "unprognostic (2.25e-2)" "unprognostic (1.04e-1)" "unprognostic (3.46e-2)" "unprognostic (1.04e-2)" "unprognostic (1.04e-1)" "unprognostic (7.55e-2)" "unprognostic (5.60e-1)" "unprognostic (1.55e-1)" "unprognostic (1.14e-1)" "unprognostic (1.77e-1)" "unprognostic (1.51e-1)" "unprognostic (1.67e-1)" "prognostic favorable (3.82e-9)" "unprognostic (4.89e-2)" "unprognostic (1.46e-1)" "unprognostic (6.58e-3)" "unprognostic (3.68e-2)" PRSS22 "BSSP-4, hBSSP-4, SP001LA" ENSG00000005001 "Serine protease 22" Q9GZN4 16 2852730-2858170 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 77.4;salivary gland: 26.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 149.0;Club cells: 240.4;Ductal cells: 104.1;Ionocytes: 445.1;Secretory cells: 110.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 24.6" "Colon - Colon enterocytes, Kidney - Endothelial cells, Liver - Cholangiocyte, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells" "Region enhanced" "Detected in some" "cerebral cortex: 2.6" "Low region specificity" "Detected in all" HPA049161 Approved Approved Nucleoplasm "Secreted in other tissues" Enzyme NA NA "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" Nucleoplasm "HPA049161: AB_2680660" "unprognostic (1.45e-1)" "unprognostic (9.80e-2)" "unprognostic (3.50e-2)" "unprognostic (4.48e-1)" "unprognostic (2.29e-4)" "unprognostic (2.58e-1)" "unprognostic (4.42e-2)" "unprognostic (1.52e-2)" "unprognostic (5.06e-1)" "unprognostic (7.52e-2)" "unprognostic (3.74e-3)" "unprognostic (4.12e-1)" "unprognostic (2.32e-4)" "unprognostic (1.04e-2)" "unprognostic (1.58e-1)" "unprognostic (1.62e-1)" "unprognostic (2.75e-1)" PSMD9 "p27, Rpn4" ENSG00000110801 "Proteasome 26S subunit, non-ATPase 9" O00233 12 121888732-121918297 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 146.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040512, HPA044220" Enhanced Supported "Plasma membrane,Cytosol" NA NA 500000 "Cluster 29: Non-specific - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 38: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" 13 Cytosol "Plasma membrane" "HPA040512: AB_2677014, HPA044220: AB_2678860" "unprognostic (2.24e-1)" "unprognostic (2.48e-3)" "unprognostic (2.12e-1)" "unprognostic (3.36e-1)" "unprognostic (1.20e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (1.32e-5)" "unprognostic (1.86e-1)" "unprognostic (6.80e-2)" "unprognostic (1.01e-1)" "unprognostic (1.46e-1)" "unprognostic (1.30e-1)" "unprognostic (9.64e-3)" "unprognostic (3.17e-2)" "unprognostic (5.73e-2)" "unprognostic (6.19e-2)" "unprognostic (8.63e-2)" PTGFRN "CD315, CD9P-1, EWI-F, FLJ11001, FPRP, KIAA1436, SMAP-6" ENSG00000134247 "Prostaglandin F2 receptor inhibitor" Q9P2B2 1 116909916-116990353 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 57.6;Cardiomyocytes: 70.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Breast - Breast myoepithelial cells, Colon - Smooth muscle cells, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017074 Approved NA NA 340000 "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 1 "HPA017074: AB_1855888" "unprognostic (1.18e-1)" "unprognostic (2.11e-3)" "unprognostic (3.03e-1)" "unprognostic (8.58e-2)" "unprognostic (3.20e-1)" "unprognostic (2.91e-2)" "unprognostic (1.48e-3)" "unprognostic (3.39e-2)" "unprognostic (1.76e-2)" "unprognostic (7.28e-2)" "unprognostic (2.77e-2)" "unprognostic (5.28e-2)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.61e-1)" "unprognostic (1.95e-1)" "unprognostic (1.12e-1)" "unprognostic (4.15e-2)" PTPA "PPP2R4, PR53" ENSG00000119383 "Protein phosphatase 2 phosphatase activator" Q15257 9 129110950-129148946 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005695, CAB022068, CAB035999, CAB080052, CAB080054, CAB080098" Approved Enhanced Nucleoplasm,Cytosol NA NA 4300000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" Nucleoplasm Cytosol "CAB022068: , CAB035999: , CAB080052: , CAB080054: , CAB080098: , HPA005695: AB_1855658" "unprognostic (4.97e-2)" "unprognostic (1.70e-2)" "unprognostic (1.13e-2)" "prognostic favorable (6.50e-5)" "unprognostic (1.56e-2)" "unprognostic (1.15e-1)" "unprognostic (6.65e-2)" "unprognostic (6.44e-3)" "unprognostic (2.22e-1)" "unprognostic (1.15e-2)" "unprognostic (3.20e-2)" "unprognostic (1.37e-1)" "unprognostic (1.01e-2)" "unprognostic (1.92e-2)" "unprognostic (1.18e-1)" "unprognostic (1.48e-1)" "unprognostic (1.69e-1)" PTS PTPS ENSG00000150787 "6-pyruvoyltetrahydropterin synthase" Q03393 11 112226367-112269955 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Tetrahydrobiopterin biosynthesis" Lyase "Disease variant, Phenylketonuria" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001481 Uncertain Approved Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 45: Non-specific - Mixed function" 8 Cytosol "HPA001481: AB_1079716" "unprognostic (2.08e-2)" "unprognostic (1.91e-1)" "unprognostic (9.66e-3)" "unprognostic (8.38e-3)" "unprognostic (4.58e-1)" "unprognostic (3.28e-3)" "unprognostic (2.38e-2)" "unprognostic (1.81e-2)" "unprognostic (2.05e-2)" "unprognostic (8.74e-2)" "unprognostic (2.59e-1)" "unprognostic (7.07e-2)" "unprognostic (3.81e-2)" "unprognostic (1.20e-2)" "unprognostic (2.97e-1)" "unprognostic (1.52e-3)" "unprognostic (1.65e-1)" PTTG1IP "C21orf1, C21orf3, PBF, PTTG1IP1" ENSG00000183255 "PTTG1 interacting protein" P53801 21 44849585-44873903 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Heart muscle - Macrophages, Lung - Endothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "CAB034146, HPA061827" Uncertain Supported Nucleoplasm NA Yes 26000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 53: Non-specific - Glycosylation" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" 10 Nucleoplasm "CAB034146: AB_1568894, HPA061827: AB_2684620" "unprognostic (1.78e-2)" "prognostic unfavorable (8.61e-4)" "unprognostic (5.24e-3)" "unprognostic (3.18e-2)" "unprognostic (1.68e-2)" "unprognostic (2.03e-2)" "unprognostic (3.59e-2)" "unprognostic (1.22e-2)" "unprognostic (1.98e-2)" "unprognostic (3.77e-2)" "prognostic unfavorable (2.28e-4)" "unprognostic (9.30e-2)" "unprognostic (3.17e-2)" "prognostic unfavorable (5.40e-4)" "unprognostic (1.38e-2)" "unprognostic (8.88e-2)" "unprognostic (1.90e-1)" PVR "CD155, HVED, Necl-5, NECL5, PVS, Tage4" ENSG00000073008 "PVR cell adhesion molecule" P15151 19 44643798-44666162 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 51.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 4.4;intermediate monocyte: 4.4;myeloid DC: 3.6;neutrophil: 1.4;non-classical monocyte: 5.1" "Group enriched" "Detected in many" 4 "dendritic cells: 3.6;granulocytes: 1.4;monocytes: 5.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012568, HPA064739" Approved Supported "Nucleoplasm,Vesicles,Plasma membrane" "Secreted - unknown location" Receptor NA NA 720000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" 52 "Nucleoplasm, Vesicles, Plasma membrane" "HPA012568: AB_1846248, HPA064739: " "unprognostic (2.90e-3)" "prognostic unfavorable (1.29e-4)" "unprognostic (3.36e-1)" "unprognostic (2.34e-1)" "unprognostic (7.89e-2)" "unprognostic (2.45e-3)" "unprognostic (3.06e-2)" "prognostic unfavorable (9.30e-4)" "unprognostic (9.05e-3)" "unprognostic (1.69e-1)" "unprognostic (2.09e-3)" "unprognostic (2.64e-3)" "unprognostic (1.69e-1)" "unprognostic (4.97e-1)" "unprognostic (1.27e-1)" "unprognostic (1.04e-3)" "prognostic unfavorable (2.75e-4)" PYROXD1 "DKFZp762G094, FLJ22028" ENSG00000121350 "Pyridine nucleotide-disulphide oxidoreductase domain 1" Q8WU10 12 21437615-21471250 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Oxidoreductase "Disease variant, Limb-girdle muscular dystrophy, Myofibrillar myopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 113.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038319, HPA038320" Uncertain Approved "Nuclear speckles" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 45: Non-specific - Mixed function" 1 "Nuclear speckles" "HPA038319: AB_10669522, HPA038320: AB_2675956" "unprognostic (1.48e-1)" "unprognostic (1.68e-1)" "unprognostic (1.15e-2)" "unprognostic (9.89e-2)" "unprognostic (1.51e-1)" "unprognostic (2.64e-3)" "unprognostic (1.50e-1)" "unprognostic (9.31e-2)" "unprognostic (8.94e-3)" "unprognostic (1.17e-2)" "unprognostic (1.57e-1)" "unprognostic (3.32e-2)" "unprognostic (1.06e-2)" "unprognostic (3.78e-2)" "unprognostic (2.30e-2)" "unprognostic (2.00e-1)" "prognostic favorable (1.70e-4)" RAB5C "RAB5CL, RABL" ENSG00000108774 "RAB5C, member RAS oncogene family" P51148 17 42124978-42155044 "Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003426, HPA004167" Approved Enhanced Endosomes NA NA 480000 "Cluster 7: Non-specific - Innate immune response" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 19: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 45: Non-specific - Mixed function" 7 Endosomes "HPA003426: AB_1079735, HPA004167: AB_2667156" "unprognostic (1.41e-1)" "unprognostic (6.02e-2)" "unprognostic (6.75e-3)" "unprognostic (3.69e-1)" "unprognostic (2.48e-1)" "prognostic unfavorable (7.08e-4)" "unprognostic (1.56e-3)" "unprognostic (4.85e-2)" "unprognostic (1.93e-1)" "unprognostic (4.52e-2)" "unprognostic (2.79e-1)" "unprognostic (2.98e-2)" "unprognostic (6.06e-3)" "unprognostic (4.37e-1)" "unprognostic (2.32e-1)" "unprognostic (2.82e-2)" "unprognostic (1.12e-2)" RAB5IF "C20orf24, PNAS-11, RCAF1, RIP5" ENSG00000101084 "RAB5 interacting factor" Q9BUV8 20 36605779-36612557 "Disease related genes, Predicted membrane proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 209.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Neutrophil_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057387, HPA076106" Uncertain Supported Mitochondria NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 7: Liver cancer - Metabolism" "Cluster 45: Non-specific - Mixed function" Mitochondria "HPA057387: AB_2683425, HPA076106: " "unprognostic (2.14e-1)" "unprognostic (4.75e-3)" "unprognostic (6.83e-2)" "unprognostic (1.78e-3)" "unprognostic (3.88e-1)" "unprognostic (2.24e-2)" "prognostic unfavorable (4.56e-6)" "unprognostic (4.47e-3)" "unprognostic (3.89e-1)" "unprognostic (2.90e-1)" "unprognostic (2.37e-2)" "unprognostic (8.60e-2)" "prognostic unfavorable (2.46e-4)" "unprognostic (2.57e-2)" "unprognostic (1.08e-1)" "unprognostic (1.00e-1)" "unprognostic (9.98e-2)" RAB7A "CMT2B, RAB7" ENSG00000075785 "RAB7A, member RAS oncogene family" P51149 3 128693669-128825942 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Autophagy, Host-virus interaction, Lipid degradation, Lipid metabolism, Protein transport, Transport" Hydrolase "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006964, CAB037131" Supported Supported Lysosomes NA NA 5700000 "Cluster 28: Neutrophils - Unknown function" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 45: Non-specific - Mixed function" 10 Lysosomes "CAB037131: AB_477460, HPA006964: AB_1856015" "unprognostic (1.99e-2)" "unprognostic (9.03e-2)" "unprognostic (1.41e-2)" "prognostic unfavorable (1.52e-4)" "unprognostic (1.45e-1)" "unprognostic (7.82e-2)" "prognostic unfavorable (9.89e-6)" "unprognostic (2.15e-2)" "unprognostic (2.38e-1)" "unprognostic (3.50e-1)" "prognostic unfavorable (4.63e-4)" "unprognostic (4.69e-1)" "unprognostic (6.73e-3)" "unprognostic (1.88e-1)" "unprognostic (1.97e-1)" "unprognostic (3.03e-3)" "unprognostic (5.64e-3)" RALA RAL ENSG00000006451 "RAS like proto-oncogene A" P11233 7 39623565-39708120 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Cell cycle, Cell division, Exocytosis" Hydrolase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 334.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047037, HPA065232" Approved Supported "Plasma membrane,Focal adhesion sites" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 34: Non-specific - Mixed function" "Cluster 7: Non-specific - Ribosome" "Cluster 67: Non-specific - Unknown function" "Cluster 45: Non-specific - Mixed function" 3 "Plasma membrane" "Focal adhesion sites" "HPA047037: , HPA065232: AB_2685440" "unprognostic (1.20e-3)" "unprognostic (1.03e-2)" "unprognostic (2.91e-1)" "unprognostic (7.73e-3)" "unprognostic (1.98e-2)" "unprognostic (9.14e-2)" "prognostic unfavorable (5.32e-5)" "unprognostic (7.71e-2)" "unprognostic (2.17e-1)" "prognostic favorable (7.46e-4)" "prognostic unfavorable (6.30e-4)" "unprognostic (3.32e-1)" "unprognostic (4.95e-3)" "unprognostic (5.38e-2)" "unprognostic (7.15e-2)" "unprognostic (2.79e-1)" "unprognostic (2.95e-2)" RAMAC "C15orf18, FAM103A1, HsT19360, MGC2560, RAM, RAMMET" ENSG00000169612 "RNA guanine-7 methyltransferase activating subunit" Q9BTL3 15 82986210-82991057 "Predicted intracellular proteins" "mRNA capping, mRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Testis - Spermatocytes, Testis - Spermatogonia" "HPA041923, HPA041948" Supported Supported Nucleoplasm No No "Cluster 35: Neutrophils - Protein binding" "Cluster 56: Non-specific - Unknown function" "Cluster 31: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 45: Non-specific - Mixed function" 37 Nucleoplasm "HPA041923: AB_10796467, HPA041948: AB_10797270" "unprognostic (1.51e-1)" "unprognostic (1.16e-2)" "unprognostic (5.30e-2)" "unprognostic (1.03e-2)" "unprognostic (2.21e-1)" "unprognostic (1.15e-1)" "unprognostic (1.96e-1)" "unprognostic (2.58e-1)" "unprognostic (2.32e-2)" "unprognostic (3.63e-3)" "unprognostic (2.09e-2)" "unprognostic (4.72e-2)" "unprognostic (7.46e-3)" "unprognostic (9.57e-2)" "unprognostic (2.72e-2)" "unprognostic (9.47e-2)" "unprognostic (2.45e-1)" RBM3 IS1-RNPL ENSG00000102317 "RNA binding motif protein 3" P98179 X 48574449-48581162 "Predicted intracellular proteins" "Stress response" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA003624, CAB062559" Enhanced Enhanced Nucleoplasm NA NA 130000 "Cluster 13: Non-specific - Mitochondria" "Cluster 18: Non-specific - Ribosome" "Cluster 30: White matter - Myelination" "Cluster 36: Non-specific - mRNA processing" "Cluster 45: Non-specific - Mixed function" 14 Nucleoplasm "CAB062559: AB_2665621, HPA003624: AB_10602123" "unprognostic (1.07e-2)" "unprognostic (1.14e-3)" "prognostic favorable (3.07e-7)" "unprognostic (1.65e-3)" "unprognostic (2.87e-1)" "unprognostic (4.05e-2)" "unprognostic (1.42e-2)" "unprognostic (1.91e-1)" "unprognostic (9.37e-2)" "unprognostic (1.63e-2)" "unprognostic (2.65e-2)" "unprognostic (2.02e-2)" "unprognostic (6.18e-2)" "unprognostic (1.10e-1)" "unprognostic (5.05e-2)" "unprognostic (3.92e-2)" "unprognostic (1.59e-1)" REG1A "PSP, PSPS, PSPS1, PTP, REG" ENSG00000115386 "Regenerating family member 1 alpha" P05451 2 79120362-79123409 "Plasma proteins, Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "pancreas: 100880.7" "Cell type enriched" "Detected in some" 14 "Exocrine glandular cells: 77260.6" "Cancer enhanced" "Detected in many" "pancreatic cancer: 1268.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 47 "breast cancer: 94.7;colorectal cancer: 64.6;Gastric cancer: 52.0;Rhabdoid: 138.8" "Low region specificity" "Detected in single" "CAB025138, HPA045549, HPA045579" Enhanced "Secreted to digestive system" "No annotated function" NA NA 68000000 "Cluster 15: Pancreas - Proteolysis" "Cluster 27: Breast cancer - Unknown function" "Cluster 45: Non-specific - Mixed function" "CAB025138: , HPA045549: AB_2679365, HPA045579: AB_2679374" "unprognostic (1.89e-1)" "unprognostic (2.91e-2)" "unprognostic (3.39e-1)" "unprognostic (1.45e-1)" "unprognostic (2.10e-1)" "unprognostic (1.63e-1)" "unprognostic (5.52e-2)" "unprognostic (3.54e-3)" "unprognostic (5.53e-2)" "unprognostic (5.54e-2)" REG1B "PSPS2, REGH, REGI-BETA, REGL" ENSG00000172023 "Regenerating family member 1 beta" P48304 2 79085023-79088019 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "pancreas: 38577.5" "Cell type enriched" "Detected in some" 7 "Exocrine glandular cells: 25526.6" "Cancer enriched" "Detected in some" 5 "pancreatic cancer: 201.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "colorectal cancer: 1.3" "HPA045549, HPA045579" Supported "Secreted to digestive system" "No annotated function" NA NA 32000000 "Cluster 15: Pancreas - Proteolysis" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Non-specific - Mixed function" "HPA045549: AB_2679365, HPA045579: AB_2679374" "unprognostic (4.08e-1)" "unprognostic (1.09e-1)" "unprognostic (3.51e-3)" "unprognostic (9.20e-2)" RFLNA "Cfm2, FAM101A, FLJ44614, RefilinA" ENSG00000178882 "Refilin A" Q6ZTI6 12 123973241-124316024 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "stomach 1: 92.2" "Cell type enhanced" "Detected in some" "Distal enterocytes: 27.5;Enteroendocrine cells: 14.7;Gastric mucus-secreting cells: 111.4;Intestinal goblet cells: 47.7;Paneth cells: 17.0;Undifferentiated cells: 14.4" "Cancer enhanced" "Detected in many" "stomach cancer: 19.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA078021 Enhanced Approved "Focal adhesion sites" NA NA "Cluster 45: Intestine - Digestion" "Cluster 49: Hindbrain - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Non-specific - Mixed function" "Focal adhesion sites" "HPA078021: AB_2732368" "unprognostic (1.71e-1)" "unprognostic (6.85e-2)" "unprognostic (1.63e-2)" "unprognostic (1.36e-1)" "unprognostic (3.15e-2)" "unprognostic (8.78e-4)" "unprognostic (2.01e-1)" "prognostic unfavorable (3.16e-5)" "unprognostic (8.87e-2)" "unprognostic (1.59e-1)" "unprognostic (1.71e-3)" "unprognostic (1.15e-3)" "unprognostic (1.77e-8)" "unprognostic (2.48e-1)" "unprognostic (1.36e-1)" "unprognostic (6.27e-2)" "unprognostic (1.37e-2)" RHOC "ARH9, ARHC" ENSG00000155366 "Ras homolog family member C" P08134 1 112701127-112707434 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 961.1;Pancreatic endocrine cells: 842.2;Proximal enterocytes: 939.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 1403.4" "Lineage enriched" "Detected in all" 4 "monocytes: 1403.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051461 Uncertain NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 44: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Non-specific - Mixed function" 2 "HPA051461: AB_2681493" "unprognostic (2.31e-2)" "unprognostic (1.23e-1)" "unprognostic (1.04e-1)" "unprognostic (1.93e-1)" "unprognostic (8.34e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (2.68e-4)" "unprognostic (2.08e-2)" "unprognostic (9.90e-2)" "unprognostic (1.40e-2)" "unprognostic (6.79e-3)" "unprognostic (3.95e-2)" "prognostic unfavorable (3.65e-5)" "unprognostic (1.26e-1)" "unprognostic (1.76e-1)" "unprognostic (3.08e-2)" "unprognostic (2.51e-3)" RHOD "ARHD, Rho, RhoHP1" ENSG00000173156 "Ras homolog family member D" O00212 11 67056847-67072017 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 177.1;liver: 119.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 115.3;Suprabasal keratinocytes: 235.2" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 7 "choroid plexus: 33.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (other)" "Group enriched" "Detected in many" 4 "cerebellum: 14.9;pons and medulla: 5.1" "Low region specificity" "Detected in some" NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" "unprognostic (2.12e-2)" "prognostic unfavorable (9.17e-4)" "unprognostic (3.89e-3)" "unprognostic (1.65e-1)" "unprognostic (3.61e-3)" "unprognostic (1.53e-1)" "unprognostic (2.99e-1)" "prognostic unfavorable (3.10e-4)" "unprognostic (5.85e-2)" "unprognostic (4.39e-2)" "unprognostic (1.38e-3)" "unprognostic (8.89e-2)" "unprognostic (2.56e-2)" "unprognostic (2.24e-1)" "unprognostic (5.89e-2)" "unprognostic (2.40e-1)" "unprognostic (2.35e-2)" RNASEH1 ENSG00000171865 "Ribonuclease H1" O60930 2 3541430-3558333 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Disease variant, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034817, HPA043037" Uncertain Approved Nucleoplasm,Cytosol "Intracellular and membrane" Enzyme NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 35: Non-specific - Mitochondria" "Cluster 14: Neurons - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 45: Non-specific - Mixed function" 5 "Nucleoplasm, Cytosol" "HPA034817: , HPA043037: AB_2678280" "unprognostic (1.64e-1)" "unprognostic (1.38e-1)" "unprognostic (8.81e-3)" "unprognostic (4.32e-3)" "unprognostic (1.79e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (7.83e-6)" "unprognostic (9.43e-2)" "unprognostic (8.46e-3)" "unprognostic (6.38e-2)" "unprognostic (2.29e-3)" "unprognostic (2.67e-1)" "unprognostic (4.06e-2)" "unprognostic (2.34e-2)" "unprognostic (2.11e-1)" "unprognostic (3.06e-2)" "unprognostic (2.23e-3)" RND1 "ARHS, Rho6, RHOS" ENSG00000172602 "Rho family GTPase 1" Q92730 12 48857145-48865870 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.0;liver: 128.6" "Cell type enhanced" "Detected in many" "Ductal cells: 212.7;Endothelial cells: 79.5;Exocrine glandular cells: 120.1;Gastric mucus-secreting cells: 54.8" "Cancer enhanced" "Detected in many" "liver cancer: 16.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 19.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077800 Supported "Vesicles,Plasma membrane,Actin filaments" NA NA "Cluster 69: Liver - Oxidoreductase activity" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 5 "Vesicles, Plasma membrane, Actin filaments" "HPA077800: AB_2686854" "unprognostic (5.60e-2)" "unprognostic (3.21e-2)" "unprognostic (2.23e-1)" "unprognostic (1.16e-1)" "unprognostic (6.90e-2)" "unprognostic (1.32e-3)" "unprognostic (3.59e-2)" "unprognostic (7.43e-2)" "unprognostic (2.21e-3)" "unprognostic (2.97e-1)" "unprognostic (1.93e-1)" "unprognostic (1.66e-1)" "unprognostic (3.89e-1)" "unprognostic (8.38e-3)" "unprognostic (6.18e-2)" "unprognostic (6.60e-2)" "unprognostic (3.35e-3)" ROMO1 "bA353C18.2, C20orf52, MTGMP" ENSG00000125995 "Reactive oxygen species modulator 1" P60602 20 35699272-35700984 "Predicted intracellular proteins, Transporters" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012782 Uncertain NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 62: Non-specific - Plasma proteins" "Cluster 45: Non-specific - Mixed function" 1 "HPA012782: AB_1845685" "unprognostic (1.55e-1)" "unprognostic (3.86e-2)" "unprognostic (3.00e-1)" "unprognostic (1.06e-1)" "unprognostic (8.83e-2)" "unprognostic (1.27e-3)" "unprognostic (5.84e-2)" "unprognostic (6.15e-2)" "unprognostic (1.21e-1)" "unprognostic (3.65e-2)" "unprognostic (7.35e-2)" "unprognostic (6.55e-2)" "unprognostic (1.83e-1)" "unprognostic (1.53e-1)" "unprognostic (2.70e-1)" "unprognostic (1.35e-1)" "unprognostic (3.47e-2)" S100A10 "42C, ANX2LG, CAL1L, CLP11, P11" ENSG00000197747 "S100 calcium binding protein A10" P60903 1 151982915-151993859 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 1711.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 4228.3;Distal enterocytes: 5741.5;Paneth cells: 4483.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 2009.9;monocytes: 1239.0;T-cells: 1183.5" "Low cancer specificity" "Detected in all" "Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003340, CAB025484" Enhanced Approved Mitochondria Yes No 270000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 9 Mitochondria "CAB025484: , HPA003340: AB_1856531" "unprognostic (2.13e-1)" "unprognostic (1.51e-3)" "unprognostic (1.01e-1)" "unprognostic (3.15e-1)" "unprognostic (6.20e-2)" "prognostic unfavorable (3.33e-4)" "prognostic unfavorable (1.00e-4)" "prognostic unfavorable (2.66e-5)" "unprognostic (1.09e-2)" "unprognostic (9.48e-2)" "prognostic unfavorable (3.88e-4)" "unprognostic (1.36e-1)" "prognostic unfavorable (3.80e-8)" "unprognostic (1.09e-1)" "unprognostic (1.50e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (3.84e-4)" S100A11 S100C ENSG00000163191 "S100 calcium binding protein A11" P31949 1 152032506-152047907 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 4618.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 5108.4;Extravillous trophoblasts: 6895.5;Suprabasal keratinocytes: 6422.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 17941.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034320, HPA042745" Enhanced Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA 7900000 "Cluster 21: Neutrophils - Unknown function" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 4 "Nucleoplasm, Cytosol" "Nuclear speckles" "CAB034320: AB_2183487, HPA042745: AB_2678142" "unprognostic (1.85e-2)" "unprognostic (9.20e-2)" "unprognostic (1.99e-1)" "unprognostic (1.61e-1)" "unprognostic (3.12e-2)" "unprognostic (7.61e-2)" "prognostic unfavorable (3.64e-5)" "unprognostic (3.34e-2)" "unprognostic (8.48e-2)" "unprognostic (1.80e-2)" "unprognostic (1.28e-3)" "unprognostic (5.92e-2)" "prognostic unfavorable (3.24e-6)" "unprognostic (2.91e-1)" "unprognostic (2.75e-1)" "unprognostic (2.43e-3)" "unprognostic (8.86e-2)" S100A13 ENSG00000189171 "S100 calcium binding protein A13" Q99584 1 153618787-153631360 "Predicted intracellular proteins, Predicted secreted proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Leydig cells: 743.6;Proximal tubular cells: 574.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 33.3" "Group enriched" "Detected in all" 5 "dendritic cells: 13.7;NK-cells: 33.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019592, CAB025494" Approved Approved "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" "Secreted in other tissues" Transport NA NA 36000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 23: Non-specific - Cellular respiration" "Cluster 19: Astrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 45: Non-specific - Mixed function" 2 "Plasma membrane, Cytosol" "Nucleoplasm, Nucleoli" "CAB025494: , HPA019592: AB_10601499" "unprognostic (1.50e-2)" "unprognostic (9.09e-2)" "unprognostic (2.08e-2)" "unprognostic (1.45e-1)" "unprognostic (7.77e-2)" "unprognostic (9.72e-3)" "unprognostic (1.75e-3)" "unprognostic (9.93e-2)" "unprognostic (6.48e-2)" "unprognostic (1.67e-1)" "unprognostic (1.21e-2)" "unprognostic (4.83e-3)" "prognostic unfavorable (1.97e-4)" "unprognostic (3.43e-2)" "unprognostic (8.10e-2)" "unprognostic (1.82e-3)" "unprognostic (1.72e-2)" S100A3 S100E ENSG00000188015 "S100 calcium binding protein A3" P33764 1 153547329-153549258 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 91.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 15.5;Ductal cells: 18.5;Endometrial stromal cells: 19.9;Exocrine glandular cells: 10.9;Ionocytes: 10.3;Pancreatic endocrine cells: 11.9" "Cancer enhanced" "Detected in all" "urothelial cancer: 26.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 9 "intermediate monocyte: 3.1;non-classical monocyte: 6.3;plasmacytoid DC: 7.5" "Group enriched" "Detected in many" 11 "dendritic cells: 7.5;monocytes: 6.3" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 20.9" "HPA042674, HPA056140" Enhanced Enhanced "Golgi apparatus,Plasma membrane,Cytosol" NA NA 240000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 13: Skin - Cornification" "Cluster 39: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 6 Cytosol "Golgi apparatus, Plasma membrane" "HPA042674: AB_10796581, HPA056140: AB_2683050" "unprognostic (3.90e-2)" "unprognostic (1.60e-1)" "unprognostic (3.59e-2)" "unprognostic (1.21e-2)" "unprognostic (4.53e-2)" "unprognostic (5.37e-3)" "unprognostic (1.48e-1)" "unprognostic (2.36e-1)" "unprognostic (2.46e-1)" "unprognostic (2.08e-1)" "unprognostic (5.34e-3)" "unprognostic (3.97e-3)" "prognostic unfavorable (1.61e-6)" "unprognostic (8.13e-2)" "unprognostic (3.46e-1)" "unprognostic (6.21e-2)" "unprognostic (8.10e-2)" S100A6 "2A9, CABP, CACY, PRA" ENSG00000197956 "S100 calcium binding protein A6" P06703 1 153534599-153536244 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 25314.5;Paneth cells: 15637.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002601, HPA007575, CAB040549, CAB047354" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 7000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 12: Non-specific - Vasculature" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 45: Non-specific - Mixed function" 11 "Plasma membrane, Cytosol" "CAB002601: , CAB040549: , CAB047354: , HPA007575: AB_1079859" "unprognostic (8.80e-3)" "unprognostic (6.96e-2)" "unprognostic (2.31e-1)" "unprognostic (2.47e-2)" "unprognostic (1.19e-1)" "unprognostic (1.19e-1)" "unprognostic (1.23e-3)" "unprognostic (1.36e-1)" "unprognostic (1.27e-1)" "unprognostic (3.51e-1)" "unprognostic (6.86e-3)" "unprognostic (1.66e-1)" "unprognostic (3.59e-1)" "unprognostic (1.10e-1)" "unprognostic (2.88e-1)" "unprognostic (1.46e-2)" "prognostic favorable (7.56e-4)" S100P ENSG00000163993 "S100 calcium binding protein P" P25815 4 6693878-6697170 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 1393.2;stomach 1: 1692.9;urinary bladder: 1708.0" "Cell type enhanced" "Detected in many" "Club cells: 1859.7;Extravillous trophoblasts: 862.6;Gastric mucus-secreting cells: 1979.7;Ionocytes: 998.1;Syncytiotrophoblasts: 2925.3" "Cancer enhanced" "Detected in many" "urothelial cancer: 564.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 46 "basophil: 1796.7;eosinophil: 839.7;neutrophil: 2984.9" "Lineage enriched" "Detected in many" 73 "granulocytes: 2984.9" "Low cancer specificity" "Detected in all" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Prostate - Urothelial cells, Skeletal muscle - Neutrophils, Stomach - Gastric mucous cells, Testis - Late spermatids, Thyroid - Neutrophils" "HPA019502, HPA075251" Enhanced Supported Nucleoplasm NA NA 1600000 "Cluster 35: Neutrophils - Protein binding" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 12: Non-specific - Vasculature" "Cluster 7: Liver cancer - Metabolism" "Cluster 45: Non-specific - Mixed function" 15 Nucleoplasm "HPA019502: AB_1856530, HPA075251: " "unprognostic (1.46e-1)" "unprognostic (1.50e-1)" "unprognostic (7.52e-2)" "unprognostic (1.44e-1)" "unprognostic (2.22e-1)" "unprognostic (7.34e-2)" "unprognostic (1.60e-3)" "unprognostic (3.92e-2)" "unprognostic (7.19e-2)" "unprognostic (9.24e-2)" "prognostic unfavorable (2.00e-4)" "unprognostic (3.87e-2)" "unprognostic (1.96e-2)" "unprognostic (1.72e-1)" "unprognostic (9.24e-2)" "unprognostic (3.65e-1)" "unprognostic (1.12e-2)" SCNN1D "dNaCh, ENaCdelta" ENSG00000162572 "Sodium channel epithelial 1 subunit delta" P51172 1 1280436-1292029 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Sodium transport, Taste, Transport" "Ion channel, Sodium channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.5;testis: 34.6" "Cell type enhanced" "Detected in many" "Astrocytes: 10.2;Early spermatids: 10.5;Horizontal cells: 8.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" HPA026884 Enhanced Supported "Plasma membrane,Actin filaments" NA NA "Cluster 78: Testis - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 45: Non-specific - Mixed function" 1 "Plasma membrane, Actin filaments" "HPA026884: AB_10601501" "unprognostic (2.08e-2)" "unprognostic (2.08e-1)" "unprognostic (7.39e-4)" "unprognostic (1.06e-2)" "unprognostic (2.74e-1)" "prognostic favorable (1.60e-4)" "unprognostic (1.44e-2)" "unprognostic (1.81e-1)" "unprognostic (2.08e-2)" "unprognostic (1.14e-1)" "prognostic favorable (1.32e-4)" "unprognostic (5.27e-2)" "prognostic unfavorable (6.67e-5)" "unprognostic (3.13e-1)" "unprognostic (4.18e-2)" "unprognostic (2.13e-1)" "unprognostic (7.06e-2)" SCTR ENSG00000080293 "Secretin receptor" P47872 2 119439843-119525301 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 25.8;pancreas: 66.0" "Group enriched" "Detected in some" 5 "Alveolar cells type 2: 29.6;Ductal cells: 96.2;Exocrine glandular cells: 95.2;Pancreatic endocrine cells: 28.9" "Cancer enhanced" "Detected in many" "pancreatic cancer: 15.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA007269 Uncertain NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 37: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" "HPA007269: AB_1856640" "unprognostic (1.51e-1)" "unprognostic (2.22e-1)" "unprognostic (4.99e-2)" "unprognostic (5.82e-2)" "unprognostic (1.71e-1)" "unprognostic (4.12e-2)" "unprognostic (1.68e-1)" "unprognostic (1.09e-1)" "unprognostic (1.68e-2)" "unprognostic (9.08e-2)" "unprognostic (7.35e-2)" "unprognostic (2.38e-2)" "unprognostic (6.11e-3)" "unprognostic (1.65e-3)" "unprognostic (1.77e-1)" "unprognostic (2.24e-1)" "unprognostic (4.38e-2)" SDC4 "amphiglycan, ryudocan, SYND4" ENSG00000124145 "Syndecan 4" P31431 20 45325288-45348424 "Cancer-related genes, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 398.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 602.0;Exocrine glandular cells: 496.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Pancreas - Ductal cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005716, CAB013240" Enhanced Approved "Golgi apparatus,Plasma membrane" "Secreted to blood" "No annotated function" NA NA 320000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 5 "Golgi apparatus" "Plasma membrane" "CAB013240: AB_2533250, HPA005716: AB_1080160" "unprognostic (1.34e-2)" "unprognostic (1.80e-1)" "unprognostic (1.71e-2)" "unprognostic (2.16e-1)" "unprognostic (5.39e-2)" "unprognostic (6.59e-3)" "unprognostic (1.16e-1)" "unprognostic (5.93e-2)" "unprognostic (2.68e-1)" "unprognostic (2.95e-2)" "prognostic unfavorable (4.20e-4)" "unprognostic (1.97e-1)" "prognostic favorable (2.44e-7)" "unprognostic (3.00e-1)" "unprognostic (2.18e-1)" "prognostic favorable (2.67e-4)" "unprognostic (7.42e-2)" SDCBP2 "SITAC18, ST-2" ENSG00000125775 "Syndecan binding protein 2" Q9H190 20 1309909-1329139 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 137.9;intestine: 133.0;stomach 1: 99.2" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 217.8;Distal enterocytes: 700.5;Ionocytes: 269.1;Paneth cells: 640.0;Proximal enterocytes: 476.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Gastric cancer: 28.9" "Colon - Colon enterocytes, Prostate - Urothelial cells, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA005804, HPA064490" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 45: Non-specific - Mixed function" 49 Nucleoplasm "Golgi apparatus, Cytosol" "HPA005804: , HPA064490: AB_2732713" "unprognostic (1.96e-2)" "unprognostic (5.44e-2)" "unprognostic (2.37e-1)" "unprognostic (5.85e-2)" "unprognostic (2.54e-1)" "unprognostic (2.27e-2)" "unprognostic (2.57e-2)" "prognostic unfavorable (2.42e-4)" "unprognostic (1.01e-1)" "unprognostic (3.78e-3)" "prognostic unfavorable (3.07e-4)" "unprognostic (3.17e-1)" "unprognostic (1.07e-2)" "unprognostic (1.30e-1)" "unprognostic (1.69e-1)" "unprognostic (1.20e-1)" "prognostic favorable (3.37e-4)" SEC14L2 "C22orf6, KIAA1186, KIAA1658, SPF, TAP, TAP1" ENSG00000100003 "SEC14 like lipid binding 2" O76054 22 30396941-30425303 "Predicted intracellular proteins" "Transcription, Transcription regulation, Transport" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 83.9;liver: 236.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 139.2;Muller glia cells: 91.7;Proximal enterocytes: 49.3;Rod photoreceptor cells: 47.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 3.8;naive CD8 T-cell: 2.7" "Lineage enriched" "Detected in single" 7 "T-cells: 3.8" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064466 Approved Supported Nucleoplasm,Cytosol NA NA 580000 "Cluster 24: Non-specific - Transcription" "Cluster 69: Liver - Oxidoreductase activity" "Cluster 19: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 45: Non-specific - Mixed function" Nucleoplasm Cytosol "HPA064466: AB_2685270" "prognostic favorable (3.05e-4)" "unprognostic (1.47e-1)" "unprognostic (1.98e-1)" "unprognostic (5.59e-3)" "unprognostic (6.51e-2)" "prognostic unfavorable (7.63e-6)" "unprognostic (1.25e-3)" "unprognostic (3.76e-3)" "unprognostic (2.23e-1)" "unprognostic (2.40e-1)" "unprognostic (2.76e-2)" "unprognostic (5.63e-3)" "unprognostic (1.17e-3)" "unprognostic (1.17e-1)" "unprognostic (1.52e-1)" "unprognostic (1.34e-3)" "unprognostic (2.01e-1)" SERPINB1 "EI, ELANH2, LEI, MNEI, PI2" ENSG00000021355 "Serpin family B member 1" P30740 6 2832332-2841959 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 461.5;esophagus: 464.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 659.9;Exocrine glandular cells: 838.4;monocytes: 795.9;Suprabasal keratinocytes: 720.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018871, HPA018882, HPA052642" Enhanced Supported "Cytoplasmic bodies" "Secreted to blood" "Enzyme inhibitor" NA NA 24000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 45: Non-specific - Mixed function" "Cytoplasmic bodies" "HPA018871: AB_1856724, HPA018882: , HPA052642: AB_2681896" "unprognostic (1.13e-2)" "unprognostic (1.93e-1)" "unprognostic (6.07e-2)" "unprognostic (1.75e-2)" "unprognostic (5.14e-3)" "unprognostic (9.67e-2)" "unprognostic (3.59e-3)" "unprognostic (1.13e-1)" "unprognostic (1.45e-1)" "unprognostic (1.88e-2)" "unprognostic (1.08e-3)" "unprognostic (9.07e-2)" "unprognostic (1.05e-1)" "unprognostic (2.16e-1)" "unprognostic (1.47e-1)" "unprognostic (1.67e-1)" "unprognostic (2.28e-1)" SERPINB7 ENSG00000166396 "Serpin family B member 7" O75635 18 63752935-63805376 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "lymphoid tissue: 37.3;skin 1: 125.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 53.4;Basal respiratory cells: 348.0;Club cells: 55.0;Ductal cells: 135.3;Extravillous trophoblasts: 91.2;Ionocytes: 113.4" "Cancer enhanced" "Detected in many" "cervical cancer: 8.0;head and neck cancer: 8.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Urothelial cells" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "cerebral cortex: 17.0;hippocampal formation: 15.1" HPA024200 Enhanced Approved "Endoplasmic reticulum,Mitochondria" NA NA 160000 "Cluster 13: Skin - Cornification" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Non-specific - Mixed function" "Endoplasmic reticulum" Mitochondria "HPA024200: AB_1856730" "unprognostic (8.66e-3)" "unprognostic (6.31e-3)" "unprognostic (6.55e-2)" "unprognostic (4.03e-4)" "unprognostic (9.11e-2)" "unprognostic (1.30e-1)" "unprognostic (1.20e-2)" "unprognostic (9.99e-2)" "unprognostic (4.70e-2)" "prognostic unfavorable (3.03e-5)" "unprognostic (2.02e-1)" "unprognostic (6.81e-2)" "unprognostic (1.62e-1)" "unprognostic (3.37e-2)" "unprognostic (2.02e-1)" "unprognostic (1.76e-3)" SERPINE1 "PAI, PAI1, PLANH1" ENSG00000106366 "Serpin family E member 1" P05121 7 101127104-101139247 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "gallbladder: 348.4;placenta: 403.7" "Cell type enhanced" "Detected in many" "Fibroblasts: 212.1;Ovarian stromal cells: 138.1;Pancreatic endocrine cells: 466.9;Syncytiotrophoblasts: 739.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 25 "NK-cell: 9.5" "Lineage enriched" "Detected in single" 25 "NK-cells: 9.5" "Cancer enhanced" "Detected in all" "Kidney cancer: 1620.4" "Colon - Neutrophils" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB068501 Uncertain "Secreted to blood" "Enzyme inhibitor" NA No 142000000 13000000 "Cluster 14: Non-specific - Unknown function" "Cluster 11: Liver - Plasma proteins" "Cluster 12: Non-specific - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" 8 "CAB068501: AB_1642775" "unprognostic (5.02e-2)" "prognostic unfavorable (5.01e-4)" "prognostic unfavorable (2.82e-4)" "unprognostic (2.10e-2)" "unprognostic (9.04e-3)" "prognostic unfavorable (2.84e-5)" "unprognostic (6.80e-3)" "prognostic unfavorable (4.41e-6)" "unprognostic (2.33e-1)" "unprognostic (1.45e-1)" "unprognostic (2.88e-3)" "unprognostic (1.58e-1)" "prognostic unfavorable (5.88e-8)" "prognostic unfavorable (3.27e-6)" "unprognostic (1.05e-1)" "unprognostic (4.33e-2)" "prognostic unfavorable (5.51e-4)" SGPL1 SPL ENSG00000166224 "Sphingosine-1-phosphate lyase 1" O95470 10 70815905-70895816 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Lipid metabolism, Sphingolipid metabolism" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 138.6" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021125, HPA023086" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 16: Non-specific - Transcription" "Cluster 39: Astrocytes - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 45: Non-specific - Mixed function" 29 "Endoplasmic reticulum" "HPA021125: AB_1856803, HPA023086: AB_1856804" "unprognostic (1.14e-1)" "unprognostic (1.77e-1)" "unprognostic (1.15e-1)" "unprognostic (3.07e-2)" "unprognostic (2.13e-1)" "unprognostic (2.34e-1)" "unprognostic (7.60e-2)" "unprognostic (2.98e-2)" "unprognostic (2.88e-1)" "unprognostic (1.06e-1)" "unprognostic (1.70e-2)" "unprognostic (2.12e-1)" "unprognostic (9.52e-2)" "unprognostic (3.42e-1)" "unprognostic (2.14e-1)" "unprognostic (9.21e-2)" "unprognostic (4.68e-3)" SH2D3A NSP1 ENSG00000125731 "SH2 domain containing 3A" Q9BRG2 19 6752160-6767463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 31.6" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 62.7;Ionocytes: 65.9;Paneth cells: 67.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Prostate - Prostate basal glandular cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "HPA035722, HPA064382" Uncertain Approved "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 6: Non-specific - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 1 Microtubules "Nucleoplasm, Cytokinetic bridge" "HPA035722: AB_10670024, HPA064382: AB_2685251" "unprognostic (3.32e-2)" "unprognostic (5.48e-2)" "unprognostic (1.82e-2)" "unprognostic (1.39e-1)" "unprognostic (1.84e-1)" "unprognostic (1.09e-1)" "unprognostic (3.96e-1)" "unprognostic (2.60e-3)" "unprognostic (3.63e-1)" "unprognostic (8.41e-2)" "unprognostic (6.48e-3)" "prognostic unfavorable (6.21e-4)" "prognostic favorable (1.42e-4)" "unprognostic (7.31e-2)" "unprognostic (1.74e-1)" "unprognostic (1.32e-3)" "unprognostic (1.81e-3)" SH3BGRL3 ENSG00000142669 "SH3 domain binding glutamate rich protein like 3" Q9H299 1 26280086-26281522 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 2346.1;Hofbauer cells: 3154.4;Langerhans cells: 2551.8;monocytes: 2493.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030848, HPA076219" Enhanced Approved "Nuclear bodies" NA NA 41000000 "Cluster 29: Non-specific - Unknown function" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 27: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 45: Non-specific - Mixed function" 2 "Nuclear bodies" "HPA030848: AB_10602398, HPA076219: AB_2686787" "unprognostic (4.97e-2)" "unprognostic (9.57e-2)" "unprognostic (1.07e-1)" "unprognostic (4.73e-3)" "unprognostic (4.95e-2)" "unprognostic (8.68e-2)" "unprognostic (4.29e-3)" "unprognostic (3.16e-1)" "unprognostic (3.62e-2)" "unprognostic (4.32e-1)" "unprognostic (1.98e-2)" "unprognostic (9.55e-2)" "prognostic unfavorable (2.17e-10)" "unprognostic (1.66e-1)" "unprognostic (1.59e-1)" "unprognostic (6.35e-2)" "unprognostic (4.43e-2)" SH3BP5L KIAA1720 ENSG00000175137 "SH3 binding domain protein 5 like" Q7L8J4 1 248810446-248825915 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 7.7;eosinophil: 4.1;neutrophil: 4.7" "Lineage enriched" "Detected in many" 6 "granulocytes: 7.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038067, HPA038068" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 79: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" 10 "Nucleoplasm, Golgi apparatus, Vesicles" "HPA038067: AB_2675814, HPA038068: AB_10670651" "unprognostic (2.48e-1)" "unprognostic (1.62e-1)" "unprognostic (5.53e-3)" "unprognostic (4.41e-1)" "unprognostic (2.78e-1)" "unprognostic (2.27e-3)" "unprognostic (1.99e-3)" "unprognostic (5.84e-2)" "unprognostic (1.29e-1)" "unprognostic (1.20e-1)" "unprognostic (2.87e-3)" "unprognostic (1.50e-2)" "unprognostic (1.13e-1)" "unprognostic (2.05e-2)" "unprognostic (1.55e-1)" "unprognostic (4.99e-2)" "unprognostic (4.66e-2)" SHB ENSG00000107338 "SH2 domain containing adaptor protein B" Q15464 9 37915898-38069227 "Predicted intracellular proteins" "Angiogenesis, Apoptosis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 22 "basophil: 2.2" "Lineage enriched" "Detected in single" 22 "granulocytes: 2.2" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010161, HPA049911, HPA052108" Uncertain Supported "Nucleoplasm,Cytosol,Cytoplasmic bodies" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 68: Non-specific - Protein processing" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 1 Cytosol "Nucleoplasm, Cytoplasmic bodies" "CAB010161: AB_2187742, HPA049911: AB_2680949, HPA052108: AB_2681730" "unprognostic (4.57e-2)" "unprognostic (1.13e-1)" "unprognostic (5.45e-2)" "unprognostic (1.63e-2)" "unprognostic (1.08e-1)" "unprognostic (7.42e-2)" "unprognostic (2.10e-1)" "unprognostic (3.38e-1)" "unprognostic (1.38e-1)" "unprognostic (1.79e-1)" "unprognostic (5.96e-3)" "unprognostic (2.48e-2)" "unprognostic (3.31e-3)" "unprognostic (7.68e-3)" "unprognostic (1.01e-1)" "unprognostic (3.29e-1)" "unprognostic (1.10e-1)" SLC35B2 UGTrel4 ENSG00000157593 "Solute carrier family 35 member B2" Q8TB61 6 44254096-44257890 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029638 Approved Approved Vesicles NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Protein processing" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 45: Non-specific - Mixed function" 9 Vesicles "HPA029638: AB_10602402" "prognostic unfavorable (7.90e-4)" "unprognostic (2.47e-3)" "unprognostic (2.30e-1)" "unprognostic (1.39e-2)" "unprognostic (2.36e-1)" "unprognostic (1.65e-2)" "prognostic unfavorable (8.59e-5)" "unprognostic (3.84e-1)" "unprognostic (2.51e-1)" "unprognostic (7.03e-3)" "unprognostic (4.27e-2)" "prognostic favorable (6.07e-4)" "unprognostic (3.60e-2)" "unprognostic (1.13e-1)" "unprognostic (4.07e-1)" "unprognostic (1.28e-1)" "unprognostic (1.06e-1)" SLC39A1 "ZIP1, ZIRTL" ENSG00000143570 "Solute carrier family 39 member 1" Q9NY26 1 153959099-153968184 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 51.0;Ductal cells: 145.0;Exocrine glandular cells: 55.8;Pancreatic endocrine cells: 59.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 7: Adipose tissue - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 45: Non-specific - Mixed function" 7 "unprognostic (6.27e-2)" "prognostic unfavorable (4.83e-4)" "unprognostic (1.13e-1)" "unprognostic (2.63e-1)" "unprognostic (2.07e-2)" "prognostic unfavorable (5.26e-5)" "prognostic unfavorable (4.12e-7)" "unprognostic (2.36e-2)" "unprognostic (2.62e-2)" "unprognostic (4.41e-1)" "unprognostic (4.83e-3)" "unprognostic (1.93e-1)" "unprognostic (5.10e-3)" "unprognostic (2.54e-2)" "unprognostic (1.23e-1)" "unprognostic (5.51e-2)" "unprognostic (6.68e-2)" SLC44A4 "C6orf29, CTL4, DFNA72, FLJ14491, NG22, TPPT" ENSG00000204385 "Solute carrier family 44 member 4" Q53GD3 6 31863192-31879046 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 128.3;prostate: 80.5;stomach 1: 81.1" "Cell type enhanced" "Detected in many" "Ciliated cells: 304.9;Club cells: 219.1;Distal enterocytes: 526.0;Gastric mucus-secreting cells: 189.2;Intestinal goblet cells: 253.6;Ionocytes: 213.9;Paneth cells: 184.9;Prostatic glandular cells: 320.8;Proximal enterocytes: 256.6" "Cancer enhanced" "Detected in many" "prostate cancer: 222.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 10.7;Gastric cancer: 10.1;prostate cancer: 27.9" "Breast - Breast glandular cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046977, HPA054176" Enhanced NA NA "Cluster 45: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Non-specific - Mixed function" "HPA046977: AB_2679887, HPA054176: AB_2682404" "unprognostic (5.84e-2)" "unprognostic (4.90e-2)" "unprognostic (3.86e-3)" "unprognostic (4.85e-3)" "unprognostic (2.75e-2)" "prognostic favorable (3.54e-4)" "unprognostic (2.65e-3)" "unprognostic (2.44e-3)" "unprognostic (3.08e-1)" "unprognostic (2.45e-1)" "unprognostic (2.89e-2)" "unprognostic (1.89e-1)" "prognostic favorable (1.06e-6)" "unprognostic (1.37e-2)" "unprognostic (2.48e-1)" "unprognostic (4.54e-2)" "prognostic favorable (6.06e-4)" SLC9B2 "FLJ23984, NHA2, NHEDC2" ENSG00000164038 "Solute carrier family 9 member B2" Q86UD5 4 103019868-103085829 "Predicted membrane proteins, Transporters" "Antiport, Hydrogen ion transport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 37.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 55.9;Exocrine glandular cells: 34.6;Hepatocytes: 37.3;Inhibitory neurons: 54.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 11.9" "Group enriched" "Detected in many" 5 "B-cells: 5.1;NK-cells: 11.9;T-cells: 6.4" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047008 Uncertain Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 69: Liver - Oxidoreductase activity" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 45: Non-specific - Mixed function" 1 "Nucleoplasm, Cell Junctions" "HPA047008: AB_2679901" "unprognostic (1.85e-1)" "unprognostic (5.43e-2)" "unprognostic (2.68e-1)" "unprognostic (1.11e-1)" "unprognostic (8.83e-2)" "unprognostic (1.23e-1)" "unprognostic (1.43e-2)" "unprognostic (3.78e-2)" "unprognostic (3.26e-1)" "unprognostic (2.53e-2)" "unprognostic (3.53e-2)" "unprognostic (1.67e-1)" "unprognostic (2.51e-5)" "unprognostic (2.23e-1)" "unprognostic (1.28e-1)" "unprognostic (1.90e-2)" "unprognostic (2.35e-5)" SMAD3 "HsT17436, JV15-2, MADH3" ENSG00000166949 "SMAD family member 3" P84022 15 67063763-67195173 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" DNA-binding "Aortic aneurysm, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 131.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008094, HPA046386, HPA067203, CAB069409" Approved Supported Nucleoplasm,Cytosol NA Yes "Cluster 3: Non-specific - Nuclear processes" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 52 Nucleoplasm Cytosol "CAB008094: AB_2302271, CAB069409: AB_1622941, HPA046386: AB_2679647, HPA067203: AB_2685803" "unprognostic (1.04e-1)" "unprognostic (1.83e-1)" "unprognostic (1.06e-1)" "unprognostic (1.99e-2)" "unprognostic (1.61e-1)" "unprognostic (1.98e-2)" "unprognostic (8.40e-3)" "unprognostic (1.80e-2)" "unprognostic (7.62e-2)" "unprognostic (6.82e-2)" "prognostic unfavorable (2.48e-4)" "unprognostic (2.93e-1)" "unprognostic (2.14e-2)" "unprognostic (3.10e-1)" "unprognostic (1.79e-1)" "unprognostic (1.15e-1)" "unprognostic (5.97e-2)" SMIM31 "h.EPR, LINC01207" ENSG00000248771 "Small integral membrane protein 31" A0A1B0GVY4 4 164754064-164803795 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "gallbladder: 7.6;intestine: 23.9;prostate: 10.6" "Cell type enhanced" "Detected in some" "Club cells: 38.2;Distal enterocytes: 75.8;Exocrine glandular cells: 45.8;Intestinal goblet cells: 89.1;Paneth cells: 36.1;Prostatic glandular cells: 53.1;Proximal enterocytes: 124.0" "Cancer enhanced" "Detected in many" "prostate cancer: 8.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.0" "Cancer enhanced" "Detected in some" "colorectal cancer: 4.1;Gastric cancer: 6.1" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Secreted - unknown location" "No annotated function" NA NA "Cluster 45: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Non-specific - Mixed function" "unprognostic (2.84e-1)" "unprognostic (1.18e-1)" "unprognostic (2.47e-2)" "unprognostic (1.87e-4)" "unprognostic (2.95e-2)" "unprognostic (1.78e-1)" "unprognostic (4.17e-2)" "unprognostic (4.82e-1)" "unprognostic (9.47e-2)" "unprognostic (5.63e-3)" SNX12 ENSG00000147164 "Sorting nexin 12" Q9UMY4 X 71056332-71073426 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB070423 Approved NA NA 89000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 45: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 45: Non-specific - Mixed function" 8 "CAB070423: AB_11153407" "unprognostic (1.54e-2)" "unprognostic (1.22e-1)" "unprognostic (3.39e-1)" "prognostic unfavorable (1.17e-4)" "unprognostic (4.83e-3)" "unprognostic (9.88e-3)" "unprognostic (1.61e-2)" "unprognostic (1.34e-1)" "unprognostic (2.46e-1)" "unprognostic (9.55e-2)" "unprognostic (1.29e-3)" "unprognostic (6.15e-2)" "prognostic favorable (1.51e-7)" "unprognostic (3.52e-2)" "unprognostic (8.81e-2)" "unprognostic (1.54e-1)" "unprognostic (9.59e-2)" SOX4 ENSG00000124766 "SRY-box transcription factor 4" Q06945 6 21593751-21598619 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 71.4;ovary: 68.6" "Cell type enhanced" "Detected in many" "dendritic cells: 1017.8;Ductal cells: 1112.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 45.8" "Group enriched" "Detected in all" 5 "dendritic cells: 45.8;granulocytes: 33.4;monocytes: 22.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "olfactory bulb: 54.2" "Low region specificity" "Detected in all" HPA029901 Approved Supported Nucleoplasm,Mitochondria NA Yes "Cluster 10: Non-specific - Membrane trafficking" "Cluster 16: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 59: Leukemia - T-cell receptor" "Cluster 45: Non-specific - Mixed function" 1 Nucleoplasm Mitochondria "HPA029901: AB_10601592" "unprognostic (4.01e-2)" "unprognostic (3.06e-1)" "unprognostic (9.28e-2)" "unprognostic (5.18e-2)" "unprognostic (5.00e-2)" "unprognostic (1.08e-2)" "prognostic unfavorable (2.57e-5)" "unprognostic (1.78e-1)" "unprognostic (8.01e-3)" "unprognostic (1.98e-2)" "unprognostic (3.88e-3)" "unprognostic (1.18e-1)" "unprognostic (8.73e-3)" "unprognostic (3.66e-2)" "unprognostic (3.31e-1)" "unprognostic (2.01e-1)" "unprognostic (9.27e-2)" SPHK1 SPHK ENSG00000176170 "Sphingosine kinase 1" Q9NYA1 17 76376584-76387860 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Calmodulin-binding, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 93.4;Lymphatic endothelial cells: 100.6;Muller glia cells: 148.2;Pancreatic endocrine cells: 113.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "olfactory bulb: 7.6" "HPA022829, HPA028761" Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Non-specific - Mixed function" 3 "Plasma membrane" Cytosol "HPA022829: AB_1857438, HPA028761: AB_10600814" "unprognostic (1.04e-1)" "unprognostic (6.30e-2)" "unprognostic (1.09e-2)" "unprognostic (8.66e-2)" "unprognostic (2.25e-2)" "unprognostic (1.82e-1)" "unprognostic (1.68e-2)" "unprognostic (9.32e-3)" "unprognostic (3.13e-1)" "unprognostic (7.43e-2)" "unprognostic (8.99e-3)" "unprognostic (2.18e-1)" "prognostic unfavorable (5.14e-6)" "unprognostic (1.39e-1)" "unprognostic (4.82e-2)" "unprognostic (8.29e-2)" "unprognostic (1.10e-3)" SPINK1 "PCTT, PSTI, Spink3, TATI" ENSG00000164266 "Serine peptidase inhibitor Kazal type 1" P00995 5 147824572-147831671 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 36 "pancreas: 51319.3" "Cell type enriched" "Detected in many" 8 "Exocrine glandular cells: 37536.5" "Cancer enhanced" "Detected in many" "pancreatic cancer: 513.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 210.0;liver cancer: 259.1" "Colon - Colon enterocytes" "Not detected" "Not detected" "Not detected" "Not detected" "CAB026366, HPA027498" Enhanced "Secreted to digestive system" "Enzyme inhibitor" NA NA 8000000 "Cluster 15: Pancreas - Proteolysis" "Cluster 11: White matter - Signal transduction" "Cluster 66: Non-specific - Mitochondria" "Cluster 45: Non-specific - Mixed function" "CAB026366: , HPA027498: AB_10603115" "unprognostic (1.05e-1)" "unprognostic (1.00e-1)" "unprognostic (9.96e-3)" "unprognostic (3.55e-1)" "unprognostic (6.12e-3)" "unprognostic (1.79e-4)" "unprognostic (8.34e-3)" "unprognostic (2.43e-1)" "unprognostic (2.66e-1)" "unprognostic (1.88e-1)" "unprognostic (3.82e-2)" "unprognostic (8.13e-2)" "prognostic unfavorable (5.44e-7)" "unprognostic (7.98e-2)" "unprognostic (2.07e-1)" "prognostic favorable (2.15e-5)" SPINT2 "HAI-2, HAI2, Kop" ENSG00000167642 "Serine peptidase inhibitor, Kunitz type 2" O43291 19 38244035-38292615 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1385.4;Syncytiotrophoblasts: 1381.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Colon enterocytes, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011101, CAB018969" Approved Uncertain "Plasma membrane,Intermediate filaments,Cytosol" No NA "Cluster 29: Non-specific - Unknown function" "Cluster 48: Stomach - Proteolysis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" "Plasma membrane, Intermediate filaments, Cytosol" "CAB018969: , HPA011101: AB_1079039" "unprognostic (5.13e-2)" "unprognostic (1.06e-3)" "unprognostic (1.40e-1)" "unprognostic (6.25e-2)" "unprognostic (1.13e-1)" "unprognostic (1.91e-2)" "unprognostic (2.23e-1)" "unprognostic (2.03e-2)" "unprognostic (3.51e-1)" "unprognostic (1.67e-2)" "unprognostic (2.89e-2)" "unprognostic (2.04e-1)" "prognostic favorable (3.41e-4)" "unprognostic (3.59e-1)" "unprognostic (1.32e-1)" "unprognostic (6.94e-2)" "unprognostic (2.68e-2)" SPPL2A "IMP3, PSL2" ENSG00000138600 "Signal peptide peptidase like 2A" Q8TCT8 15 50702266-50765948 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Skeletal myocytes: 244.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036062, HPA067304" Enhanced Supported Vesicles NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 35: Non-specific - Mitochondria" "Cluster 8: Immune cells - Immune response" "Cluster 58: Non-specific - Nuclear processes" "Cluster 45: Non-specific - Mixed function" 2 Vesicles "HPA036062: AB_10611670, HPA067304: AB_2685820" "unprognostic (1.66e-1)" "unprognostic (1.03e-1)" "unprognostic (2.70e-1)" "unprognostic (5.82e-3)" "unprognostic (3.71e-1)" "unprognostic (1.70e-1)" "unprognostic (2.15e-1)" "unprognostic (1.88e-1)" "unprognostic (2.22e-2)" "unprognostic (6.36e-2)" "unprognostic (2.04e-2)" "unprognostic (4.00e-2)" "unprognostic (3.11e-2)" "unprognostic (2.26e-2)" "unprognostic (1.44e-2)" "unprognostic (6.96e-2)" "unprognostic (3.66e-1)" SQSTM1 "A170, OSIL, p60, p62, p62B, PDB3" ENSG00000161011 "Sequestosome 1" Q13501 5 179806398-179838078 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Autophagy, Differentiation, Immunity" "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1141.6" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 2518.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004587, HPA064165, HPA068843" Supported Supported Vesicles,Cytosol No No 81000 "Cluster 21: Neutrophils - Unknown function" "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 55: Non-specific - Transcription" "Cluster 7: Liver cancer - Metabolism" "Cluster 45: Non-specific - Mixed function" 36 "Vesicles, Cytosol" "CAB004587: AB_628279, HPA064165: AB_2685203, HPA068843: AB_2732120" "unprognostic (1.08e-1)" "unprognostic (1.39e-1)" "unprognostic (3.19e-1)" "unprognostic (9.45e-2)" "unprognostic (1.47e-2)" "unprognostic (1.08e-1)" "prognostic unfavorable (2.31e-5)" "unprognostic (1.34e-1)" "unprognostic (2.34e-1)" "unprognostic (5.65e-2)" "unprognostic (1.66e-1)" "unprognostic (1.70e-1)" "unprognostic (9.52e-2)" "unprognostic (3.21e-1)" "unprognostic (8.68e-3)" "unprognostic (4.41e-2)" "unprognostic (2.01e-1)" SRA1 "SRA, STRAA1" ENSG00000213523 "Steroid receptor RNA activator 1" Q9HD15 5 140537340-140557677 "Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" "Activator, Receptor, Ribonucleoprotein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044598, HPA050153" Approved Supported "Nucleoplasm,Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 35: Non-specific - Mitochondria" "Cluster 35: Non-specific - DNA binding" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 45: Non-specific - Mixed function" 1 Nucleoplasm "Microtubules, Cytokinetic bridge, Cytosol" "HPA044598: AB_2679013, HPA050153: AB_2681033" "unprognostic (1.51e-1)" "unprognostic (1.04e-2)" "unprognostic (8.69e-2)" "prognostic favorable (8.01e-6)" "unprognostic (9.32e-2)" "unprognostic (2.56e-1)" "unprognostic (2.90e-1)" "unprognostic (2.43e-1)" "unprognostic (9.38e-2)" "unprognostic (7.41e-2)" "unprognostic (5.58e-3)" "unprognostic (2.61e-1)" "unprognostic (5.34e-2)" "unprognostic (3.10e-2)" "unprognostic (3.01e-2)" "unprognostic (3.71e-1)" "unprognostic (1.04e-1)" STOML1 "FLJ36370, hUNC-24, SLP-1, STORP" ENSG00000067221 "Stomatin like 1" Q9UBI4 15 73978926-73994622 "Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 49.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042353 Approved Approved Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 33: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 45: Non-specific - Mixed function" 1 Cytosol "HPA042353: AB_10797387" "unprognostic (5.75e-2)" "unprognostic (1.70e-1)" "unprognostic (7.76e-2)" "unprognostic (4.54e-3)" "unprognostic (1.39e-2)" "unprognostic (1.81e-2)" "unprognostic (1.54e-1)" "unprognostic (2.45e-1)" "unprognostic (1.78e-1)" "unprognostic (2.64e-1)" "unprognostic (1.13e-1)" "unprognostic (2.30e-3)" "unprognostic (2.26e-3)" "unprognostic (2.14e-1)" "unprognostic (1.37e-1)" "unprognostic (1.55e-1)" "unprognostic (2.67e-2)" SZRD1 "C1orf144, DKFZp566C0424" ENSG00000055070 "SUZ RNA binding domain containing 1" Q7Z422 1 16352575-16398145 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024221 Uncertain Approved Nucleoplasm,Cytosol NA NA 17000 "Cluster 40: Monocytes - Innate immune response" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 45: Non-specific - Mixed function" "Nucleoplasm, Cytosol" "HPA024221: AB_10603450" "unprognostic (3.52e-2)" "unprognostic (1.28e-1)" "unprognostic (1.41e-1)" "unprognostic (1.53e-1)" "unprognostic (1.09e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (5.98e-6)" "unprognostic (2.53e-1)" "unprognostic (9.07e-2)" "unprognostic (1.48e-1)" "unprognostic (1.31e-1)" "unprognostic (7.43e-2)" "unprognostic (1.25e-2)" "unprognostic (1.21e-1)" "unprognostic (2.17e-1)" "unprognostic (2.76e-2)" "unprognostic (7.60e-2)" TAPBP TAPA ENSG00000231925 "TAP binding protein" O15533 6 33299694-33314284 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007066, CAB080405" Approved Approved "Nucleoli,Plasma membrane,Mitochondria" NA NA 20000 "Cluster 32: Basophils - Transcription" "Cluster 47: Spleen - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 45: Non-specific - Mixed function" 2 "Nucleoli, Plasma membrane" Mitochondria "CAB080405: , HPA007066: AB_1857769" "prognostic favorable (2.76e-4)" "unprognostic (1.43e-2)" "unprognostic (7.01e-2)" "unprognostic (1.98e-2)" "unprognostic (1.59e-3)" "unprognostic (2.03e-1)" "unprognostic (1.37e-1)" "unprognostic (8.21e-2)" "prognostic favorable (6.29e-4)" "unprognostic (1.67e-2)" "unprognostic (2.37e-1)" "unprognostic (3.63e-1)" "unprognostic (1.61e-2)" "unprognostic (3.82e-1)" "unprognostic (1.19e-2)" "unprognostic (1.21e-1)" "unprognostic (6.54e-3)" TAX1BP3 TIP-1 ENSG00000213977 "Tax1 binding protein 3" O14907 17 3662895-3668679 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 369.9;Ductal cells: 332.4;Exocrine glandular cells: 315.1;Pancreatic endocrine cells: 353.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 164.7;granulocytes: 218.6;monocytes: 78.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046410, HPA063078" Approved Supported "Nucleoli fibrillar center,Vesicles,Actin filaments" NA NA 120000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 45: Non-specific - Mixed function" 1 "Nucleoli fibrillar center" "Vesicles, Actin filaments" "HPA046410: AB_2679656, HPA063078: AB_2684937" "unprognostic (6.15e-2)" "unprognostic (6.46e-3)" "unprognostic (3.37e-1)" "unprognostic (1.32e-1)" "prognostic unfavorable (2.17e-4)" "unprognostic (1.68e-1)" "unprognostic (1.12e-3)" "prognostic unfavorable (1.76e-4)" "unprognostic (1.80e-2)" "unprognostic (5.45e-3)" "unprognostic (5.19e-2)" "unprognostic (2.87e-1)" "prognostic unfavorable (7.90e-4)" "unprognostic (5.12e-2)" "unprognostic (2.10e-1)" "unprognostic (2.10e-3)" "unprognostic (1.92e-1)" TBC1D22B "C6orf197, dJ744I24.2, FLJ20337" ENSG00000065491 "TBC1 domain family member 22B" Q9NU19 6 37257772-37332970 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027908, HPA027909, HPA027910" Uncertain Uncertain Nucleoplasm,Cytosol NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 45: Non-specific - Mixed function" 46 "Nucleoplasm, Cytosol" "HPA027908: AB_10602073, HPA027909: AB_10601857, HPA027910: AB_10602203" "unprognostic (9.83e-2)" "unprognostic (5.36e-2)" "unprognostic (2.17e-2)" "prognostic unfavorable (8.15e-5)" "unprognostic (2.70e-1)" "unprognostic (1.45e-1)" "unprognostic (2.29e-2)" "unprognostic (1.44e-1)" "unprognostic (9.48e-2)" "unprognostic (6.06e-3)" "unprognostic (3.10e-2)" "unprognostic (1.46e-1)" "unprognostic (3.53e-3)" "unprognostic (9.87e-2)" "unprognostic (2.71e-1)" "unprognostic (3.19e-1)" "unprognostic (9.73e-2)" TBC1D3D ENSG00000274419 "TBC1 domain family member 3D" A0A087WVF3 17 38003976-38014908 "Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cholangiocytes: 1.9;Cone photoreceptor cells: 1.7;Exocrine glandular cells: 1.3;Kupffer cells: 1.4;Rod photoreceptor cells: 2.0;Syncytiotrophoblasts: 2.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "HPA046969, HPA047745, HPA052553" Approved Uncertain Vesicles NA NA "Cluster 78: Testis - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 59: Leukemia - T-cell receptor" "Cluster 45: Non-specific - Mixed function" Vesicles "HPA046969: , HPA047745: AB_2680144, HPA052553: AB_2681869" TEAD2 "ETF, TEF-4, TEF4" ENSG00000074219 "TEA domain transcription factor 2" Q15562 19 49340595-49362457 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 48.3;Early spermatids: 75.6;Late spermatids: 38.8;Lymphatic endothelial cells: 38.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 22 "memory B-cell: 1.7;naive B-cell: 2.7" "Lineage enriched" "Detected in single" 27 "B-cells: 2.7" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Skin - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066292, HPA069963" Supported Nucleoplasm NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 5: Rhabdoid - Unknown function" "Cluster 45: Non-specific - Mixed function" 4 Nucleoplasm "HPA066292: AB_2685651, HPA069963: AB_2686222" "unprognostic (2.69e-2)" "unprognostic (1.08e-1)" "unprognostic (2.09e-1)" "unprognostic (1.03e-2)" "unprognostic (8.58e-3)" "unprognostic (4.39e-1)" "prognostic unfavorable (8.66e-4)" "unprognostic (2.91e-1)" "unprognostic (4.47e-3)" "unprognostic (1.11e-1)" "unprognostic (3.96e-3)" "unprognostic (1.24e-1)" "unprognostic (4.39e-2)" "unprognostic (2.39e-2)" "unprognostic (1.08e-1)" "unprognostic (1.31e-1)" "unprognostic (6.78e-2)" TFF1 "BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2" ENSG00000160182 "Trefoil factor 1" P04155 21 42362282-42366535 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 48 "stomach 1: 7747.8" "Group enriched" "Detected in many" 8 "Gastric mucus-secreting cells: 10966.3;Intestinal goblet cells: 2798.0" "Group enriched" "Detected in many" 10 "breast cancer: 402.1;colorectal cancer: 268.3;pancreatic cancer: 805.7;stomach cancer: 744.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 10 "breast cancer: 1444.6" "Colon - Colon enterocytes, Pancreas - Ductal cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002170, HPA003425" Enhanced "Secreted to digestive system" "Growth factor" NA NA 950000 "Cluster 48: Stomach - Proteolysis" "Cluster 27: Breast cancer - Unknown function" "Cluster 45: Non-specific - Mixed function" 9 "CAB002170: AB_563985, HPA003425: AB_1848260" "prognostic favorable (5.00e-4)" "unprognostic (8.81e-3)" "unprognostic (9.82e-2)" "prognostic favorable (5.67e-4)" "unprognostic (2.42e-1)" "unprognostic (1.72e-3)" "unprognostic (8.14e-2)" "unprognostic (2.45e-1)" "unprognostic (1.52e-1)" "unprognostic (6.62e-2)" "unprognostic (1.01e-1)" "unprognostic (1.19e-1)" "unprognostic (7.72e-3)" "unprognostic (1.07e-1)" TGFA ENSG00000163235 "Transforming growth factor alpha" P01135 2 70447284-70554193 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 24.7" "Cell type enhanced" "Detected in many" "Ductal cells: 31.3;Early spermatids: 30.9;Oligodendrocyte precursor cells: 55.7;Oligodendrocytes: 33.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 11.4;eosinophil: 23.9;neutrophil: 24.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 24.0" "Cancer enhanced" "Detected in many" "Kidney cancer: 179.0" "Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042297 Approved Approved Vesicles "Secreted to blood" "Growth factor" No No 57900 "Cluster 21: Neutrophils - Unknown function" "Cluster 34: Non-specific - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" 3 Vesicles "HPA042297: AB_10793878" "unprognostic (1.23e-1)" "unprognostic (1.06e-3)" "unprognostic (3.57e-3)" "unprognostic (6.39e-2)" "unprognostic (1.41e-1)" "unprognostic (8.49e-3)" "unprognostic (1.52e-1)" "unprognostic (3.00e-3)" "unprognostic (6.69e-2)" "unprognostic (9.21e-2)" "prognostic unfavorable (1.20e-5)" "unprognostic (7.74e-2)" "unprognostic (3.70e-2)" "unprognostic (1.60e-1)" "unprognostic (9.21e-2)" "prognostic favorable (1.52e-4)" "unprognostic (9.19e-2)" TJP2 "DFNA51, X104, ZO-2, ZO2" ENSG00000119139 "Tight junction protein 2" Q9UDY2 9 69121264-69274615 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 72.5;Oligodendrocytes: 76.8;Rod photoreceptor cells: 47.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001813, CAB009228, HPA070714" Supported Enhanced "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 580000 "Cluster 40: Monocytes - Innate immune response" "Cluster 39: Retina & Testis - Cilium" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 5 "Plasma membrane, Cell Junctions" Nucleoplasm "CAB009228: AB_2203583, HPA001813: AB_1080764, HPA070714: AB_2732161" "unprognostic (1.30e-1)" "unprognostic (7.69e-2)" "unprognostic (1.23e-3)" "unprognostic (7.68e-2)" "unprognostic (2.01e-1)" "unprognostic (8.83e-3)" "unprognostic (1.94e-2)" "unprognostic (1.86e-1)" "unprognostic (4.82e-2)" "unprognostic (3.30e-2)" "unprognostic (2.93e-3)" "unprognostic (3.60e-1)" "prognostic favorable (1.78e-14)" "unprognostic (3.29e-2)" "unprognostic (6.42e-2)" "unprognostic (8.15e-3)" "unprognostic (5.85e-2)" TMBIM1 "LFG3, PP1201, RECS1" ENSG00000135926 "Transmembrane BAX inhibitor motif containing 1" Q969X1 2 218274197-218292586 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 299.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012093, HPA070824" Approved Supported Vesicles NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 7 Vesicles "HPA012093: AB_1858056, HPA070824: AB_2686317" "unprognostic (4.36e-2)" "unprognostic (1.70e-1)" "unprognostic (1.13e-1)" "unprognostic (1.73e-3)" "unprognostic (2.34e-3)" "unprognostic (3.81e-3)" "unprognostic (8.91e-3)" "unprognostic (5.58e-3)" "unprognostic (9.85e-2)" "unprognostic (3.76e-3)" "prognostic unfavorable (4.22e-4)" "unprognostic (1.69e-1)" "prognostic favorable (3.38e-4)" "unprognostic (1.22e-1)" "unprognostic (4.63e-2)" "unprognostic (2.75e-2)" "unprognostic (4.50e-1)" TMEM102 "CBAP, FLJ36878" ENSG00000181284 "Transmembrane protein 102" Q8N9M5 17 7435435-7437679 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 72.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "eosinophil: 3.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA024433 Uncertain Approved Vesicles NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 47: Endothelial cells - Vasculature" "Cluster 42: Non-specific - Unknown function" "Cluster 45: Non-specific - Mixed function" 4 Vesicles "HPA024433: AB_1858071" "unprognostic (2.42e-2)" "unprognostic (2.52e-2)" "unprognostic (1.54e-2)" "unprognostic (1.64e-1)" "unprognostic (1.10e-2)" "unprognostic (9.24e-2)" "unprognostic (2.46e-1)" "unprognostic (1.61e-1)" "unprognostic (2.91e-2)" "unprognostic (2.69e-2)" "unprognostic (2.69e-1)" "unprognostic (4.95e-2)" "prognostic favorable (9.90e-4)" "unprognostic (1.10e-3)" "unprognostic (8.40e-2)" "unprognostic (1.67e-1)" "unprognostic (1.42e-3)" TMEM134 FLJ21749 ENSG00000172663 "Transmembrane protein 134" Q9H6X4 11 67461710-67469272 "Predicted membrane proteins, Transporters" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043744 Approved Supported Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 21: Testis - Unknown function" "Cluster 7: Non-specific - Ribosome" "Cluster 24: Non-specific - Unknown function" "Cluster 45: Non-specific - Mixed function" Cytosol "HPA043744: AB_10794773" "unprognostic (1.44e-1)" "unprognostic (1.08e-1)" "unprognostic (1.22e-1)" "unprognostic (4.67e-2)" "unprognostic (8.66e-2)" "unprognostic (1.39e-1)" "unprognostic (1.10e-1)" "unprognostic (7.22e-2)" "unprognostic (3.85e-1)" "unprognostic (1.39e-2)" "unprognostic (4.30e-2)" "unprognostic (3.48e-1)" "unprognostic (1.75e-1)" "unprognostic (3.12e-2)" "unprognostic (1.70e-1)" "unprognostic (1.30e-2)" "unprognostic (4.43e-3)" TMEM217 "C6orf128, dJ355M6.2" ENSG00000172738 "Transmembrane protein 217" Q8N7C4 6 37212180-37258155 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 8.7" "Cell type enhanced" "Detected in many" "Ductal cells: 10.8;Exocrine glandular cells: 12.7;Mucus glandular cells: 27.1;Spermatocytes: 14.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045432, HPA071187" Approved Nucleoli,Cytosol NA NA "Cluster 46: Testis - Spermatogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 45: Non-specific - Mixed function" Nucleoli Cytosol "HPA045432: AB_2732519, HPA071187: AB_2732174" "unprognostic (7.78e-2)" "unprognostic (5.49e-2)" "unprognostic (2.22e-2)" "unprognostic (1.29e-2)" "unprognostic (7.79e-2)" "unprognostic (2.02e-1)" "unprognostic (6.77e-3)" "unprognostic (1.40e-2)" "unprognostic (3.51e-2)" "unprognostic (4.23e-4)" "unprognostic (8.22e-2)" "unprognostic (2.18e-1)" "unprognostic (5.62e-2)" "unprognostic (7.26e-2)" "unprognostic (1.33e-2)" "unprognostic (6.99e-2)" "unprognostic (1.59e-1)" TMEM50A SMP1 ENSG00000183726 "Transmembrane protein 50A" O95807 1 25338317-25362361 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065192 Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 52: Kidney - Transmembrane transport" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 45: Non-specific - Mixed function" 9 "Plasma membrane" "Actin filaments, Cytosol" "HPA065192: AB_2685429" "unprognostic (2.41e-2)" "unprognostic (2.74e-1)" "unprognostic (5.17e-3)" "prognostic favorable (8.64e-5)" "unprognostic (1.45e-1)" "unprognostic (2.04e-2)" "prognostic unfavorable (3.34e-4)" "unprognostic (7.39e-2)" "unprognostic (7.92e-3)" "unprognostic (2.53e-1)" "unprognostic (1.02e-2)" "unprognostic (2.44e-2)" "unprognostic (2.39e-3)" "unprognostic (6.66e-2)" "unprognostic (2.91e-1)" "unprognostic (3.91e-3)" "unprognostic (3.44e-2)" TMEM51 "C1orf72, FLJ10199" ENSG00000171729 "Transmembrane protein 51" Q9NW97 1 15152532-15220478 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 84.5;Exocrine glandular cells: 75.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skeletal muscle - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014547, HPA019441" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 25: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 32 "Nucleoplasm, Cytosol" "HPA014547: AB_1858121, HPA019441: AB_2670142" "unprognostic (1.21e-1)" "unprognostic (1.84e-1)" "unprognostic (8.74e-2)" "unprognostic (1.89e-2)" "unprognostic (3.61e-2)" "unprognostic (8.01e-2)" "unprognostic (1.47e-2)" "unprognostic (7.81e-3)" "unprognostic (7.84e-2)" "unprognostic (1.39e-1)" "unprognostic (3.00e-2)" "unprognostic (8.91e-2)" "prognostic favorable (8.16e-8)" "unprognostic (1.11e-1)" "unprognostic (1.22e-1)" "unprognostic (5.58e-2)" "unprognostic (1.67e-3)" TMEM87B FLJ14681 ENSG00000153214 "Transmembrane protein 87B" Q96K49 2 112055269-112119318 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 83.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035183 Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 45: Intestine - Digestion" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" "Golgi apparatus, Vesicles" "HPA035183: AB_10600829" "unprognostic (3.19e-1)" "prognostic unfavorable (3.78e-4)" "unprognostic (1.26e-2)" "unprognostic (1.79e-1)" "unprognostic (1.39e-1)" "prognostic unfavorable (4.28e-4)" "prognostic unfavorable (4.72e-4)" "unprognostic (4.20e-3)" "unprognostic (1.85e-1)" "unprognostic (6.07e-2)" "unprognostic (2.87e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.52e-7)" "unprognostic (1.32e-1)" "unprognostic (5.35e-2)" "unprognostic (1.05e-1)" "unprognostic (3.25e-3)" TMPRSS3 "DFNB10, DFNB8" ENSG00000160183 "Transmembrane serine protease 3" P57727 21 42371887-42396091 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 22.9;stomach 1: 14.1" "Cell type enhanced" "Detected in many" "Breast glandular cells: 16.9;Cholangiocytes: 24.8;Ciliated cells: 32.8;Ductal cells: 15.5;Gastric mucus-secreting cells: 27.1;Mucus glandular cells: 15.7;Muller glia cells: 18.8;Secretory cells: 22.3" "Cancer enhanced" "Detected in many" "ovarian cancer: 16.6" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 3.2" "Lineage enriched" "Detected in single" 6 "T-cells: 3.2" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 59: Fallopian tube - Tissue development" "Cluster 19: Astrocytes - Mixed function" "Cluster 20: Myeloma - Immune response" "Cluster 45: Non-specific - Mixed function" "unprognostic (8.47e-3)" "unprognostic (2.83e-1)" "prognostic unfavorable (3.64e-4)" "unprognostic (2.85e-1)" "unprognostic (2.45e-3)" "unprognostic (3.97e-2)" "unprognostic (1.43e-1)" "unprognostic (8.17e-2)" "unprognostic (9.62e-2)" "unprognostic (4.81e-2)" "unprognostic (2.65e-1)" "unprognostic (1.42e-1)" "prognostic unfavorable (8.24e-4)" "unprognostic (2.66e-2)" "unprognostic (2.73e-1)" "unprognostic (8.00e-2)" "unprognostic (1.33e-1)" TMSB10 TB10 ENSG00000034510 "Thymosin beta 10" P63313 2 84905656-84906671 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 13369.8;Paneth cells: 20566.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells" "Not detected" "Not detected" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 16: Non-specific - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 45: Non-specific - Mixed function" 3 "unprognostic (3.60e-1)" "unprognostic (4.52e-2)" "unprognostic (7.03e-2)" "unprognostic (6.19e-3)" "unprognostic (2.61e-2)" "unprognostic (4.73e-2)" "unprognostic (1.17e-3)" "unprognostic (3.26e-3)" "unprognostic (2.99e-2)" "unprognostic (2.76e-3)" "unprognostic (2.20e-3)" "unprognostic (7.24e-2)" "prognostic unfavorable (8.49e-7)" "unprognostic (1.28e-1)" "unprognostic (2.83e-1)" "prognostic favorable (4.97e-5)" "unprognostic (3.16e-2)" TMUB1 "C7orf21, HOPS, SB144" ENSG00000164897 "Transmembrane and ubiquitin like domain containing 1" Q9BVT8 7 151081085-151083493 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 188.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029429 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 19: Astrocytes - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" 7 Nucleoplasm Cytosol "HPA029429: AB_10601825" "unprognostic (8.14e-2)" "unprognostic (2.19e-2)" "unprognostic (2.76e-3)" "unprognostic (1.30e-1)" "unprognostic (7.23e-3)" "unprognostic (7.04e-2)" "unprognostic (2.12e-3)" "unprognostic (7.73e-2)" "unprognostic (1.25e-1)" "unprognostic (2.93e-2)" "unprognostic (1.74e-2)" "unprognostic (2.24e-1)" "unprognostic (1.97e-2)" "unprognostic (2.49e-3)" "unprognostic (2.74e-1)" "unprognostic (1.03e-1)" "unprognostic (3.31e-2)" TNFAIP1 "B12, B61, BTBD34, EDP1, MGC2317" ENSG00000109079 "TNF alpha induced protein 1" Q13829 17 28335602-28347009 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Colon - Endothelial cells, Lung - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013333, HPA014641" Uncertain Approved Nucleoli NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 7: Adipose tissue - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Non-specific - Mixed function" 31 Nucleoli "HPA013333: AB_1858160, HPA014641: AB_1858159" "unprognostic (4.42e-1)" "unprognostic (1.54e-2)" "unprognostic (4.32e-2)" "prognostic unfavorable (7.48e-5)" "unprognostic (2.29e-1)" "unprognostic (4.97e-3)" "unprognostic (3.21e-1)" "unprognostic (1.94e-1)" "unprognostic (2.64e-2)" "unprognostic (1.31e-2)" "unprognostic (8.27e-3)" "unprognostic (1.43e-2)" "unprognostic (4.21e-3)" "unprognostic (2.49e-2)" "unprognostic (2.04e-1)" "unprognostic (4.09e-1)" "unprognostic (7.02e-2)" TNFRSF12A "CD266, FN14, TweakR" ENSG00000006327 "TNF receptor superfamily member 12A" Q9NP84 16 3018445-3022383 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Apoptosis, Cell adhesion, Differentiation" "Developmental protein, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 574.8;Basal respiratory cells: 577.5;Ductal cells: 809.1;Exocrine glandular cells: 535.5;Pancreatic endocrine cells: 706.4;Secretory cells: 888.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "eosinophil: 140.0;neutrophil: 103.3" "Lineage enriched" "Detected in many" 10 "granulocytes: 140.0" "Low cancer specificity" "Detected in all" "Pancreas - Ductal cells" "Low region specificity" "Detected in all" HPA007853 Approved Supported "Plasma membrane,Cytosol" NA Yes 370000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 68: Non-specific - Protein processing" "Cluster 12: Non-specific - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" 5 "Plasma membrane" Cytosol "HPA007853: AB_1858463" "unprognostic (1.44e-1)" "unprognostic (2.46e-3)" "unprognostic (8.90e-2)" "unprognostic (2.60e-1)" "unprognostic (4.06e-3)" "prognostic unfavorable (5.50e-4)" "unprognostic (7.04e-3)" "unprognostic (1.98e-3)" "unprognostic (4.17e-3)" "unprognostic (2.85e-1)" "unprognostic (5.02e-3)" "unprognostic (3.88e-1)" "prognostic unfavorable (8.78e-4)" "unprognostic (2.98e-2)" "unprognostic (6.00e-2)" "unprognostic (2.80e-3)" "unprognostic (2.17e-2)" TNFRSF21 "CD358, DR6" ENSG00000146072 "TNF receptor superfamily member 21" O75509 6 47231532-47309905 "CD markers, Plasma proteins, Predicted membrane proteins" "Adaptive immunity, Apoptosis, Host-virus interaction, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 109.7;urinary bladder: 142.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 129.4;dendritic cells: 182.3;Syncytiotrophoblasts: 154.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 35 "plasmacytoid DC: 69.3" "Lineage enriched" "Detected in single" 302 "dendritic cells: 69.3" "Low cancer specificity" "Detected in many" "Prostate - Urothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006746, CAB009805" Approved Supported "Plasma membrane,Cytosol" NA NA 2300000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 34: Non-specific - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 2 "Plasma membrane, Cytosol" "CAB009805: AB_2206956, HPA006746: AB_1078701" "unprognostic (1.19e-2)" "unprognostic (2.70e-1)" "unprognostic (3.26e-1)" "unprognostic (7.85e-2)" "unprognostic (1.44e-1)" "unprognostic (3.41e-2)" "unprognostic (9.80e-3)" "unprognostic (1.11e-1)" "unprognostic (1.46e-2)" "unprognostic (7.53e-2)" "unprognostic (1.38e-3)" "unprognostic (1.74e-1)" "prognostic favorable (7.23e-6)" "unprognostic (1.48e-1)" "unprognostic (1.34e-1)" "unprognostic (9.78e-2)" "unprognostic (1.45e-2)" TNIP1 "ABIN-1, KIAA0113, NAF1, VAN" ENSG00000145901 "TNFAIP3 interacting protein 1" Q15025 5 151029945-151093577 "Human disease related genes, Predicted intracellular proteins" "Inflammatory response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 260.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037893, HPA037894, HPA071950" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 56: Non-specific - Unknown function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 67 Nucleoplasm Cytosol "HPA037893: AB_10672468, HPA037894: AB_2675723, HPA071950: AB_2686476" "prognostic favorable (5.69e-4)" "unprognostic (1.08e-1)" "unprognostic (1.10e-1)" "prognostic favorable (6.86e-5)" "unprognostic (7.45e-3)" "unprognostic (2.94e-1)" "unprognostic (5.35e-3)" "unprognostic (1.45e-2)" "unprognostic (2.82e-1)" "unprognostic (3.42e-1)" "unprognostic (2.25e-2)" "unprognostic (1.96e-1)" "unprognostic (7.68e-3)" "unprognostic (1.47e-1)" "unprognostic (4.69e-2)" "unprognostic (2.29e-1)" "unprognostic (9.84e-2)" TOM1L1 SRCASM ENSG00000141198 "Target of myb1 like 1 membrane trafficking protein" O75674 17 54899387-54961956 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 187.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022916 Uncertain NA NA "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 45: Non-specific - Mixed function" 6 "HPA022916: AB_1858181" "unprognostic (1.50e-1)" "unprognostic (7.70e-3)" "prognostic favorable (1.61e-4)" "unprognostic (9.59e-2)" "unprognostic (1.59e-3)" "unprognostic (6.26e-3)" "unprognostic (1.18e-2)" "unprognostic (1.32e-1)" "unprognostic (2.49e-3)" "unprognostic (2.00e-2)" "unprognostic (2.14e-1)" "unprognostic (3.87e-2)" "prognostic favorable (3.81e-6)" "unprognostic (7.47e-2)" "unprognostic (1.12e-1)" "unprognostic (1.24e-1)" "unprognostic (3.62e-2)" TPI1 ENSG00000111669 "Triosephosphate isomerase 1" P60174 12 6867119-6870948 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Gluconeogenesis, Glycolysis" "Isomerase, Lyase" "Cancer-related genes, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 2384.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050924, HPA053568" Uncertain Approved Nucleoplasm NA NA 170000000 "Cluster 29: Non-specific - Unknown function" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 14: Neurons - Synaptic function" "Cluster 38: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" 4 Nucleoplasm "HPA050924: AB_2681276, HPA053568: AB_2682193" "unprognostic (2.85e-1)" "unprognostic (5.58e-3)" "unprognostic (1.65e-1)" "unprognostic (1.62e-2)" "unprognostic (6.94e-2)" "unprognostic (2.31e-2)" "prognostic unfavorable (1.04e-5)" "unprognostic (4.14e-3)" "unprognostic (7.49e-2)" "unprognostic (2.13e-2)" "unprognostic (2.11e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (6.54e-4)" "unprognostic (7.04e-2)" "unprognostic (1.82e-1)" "unprognostic (1.53e-1)" "unprognostic (1.11e-2)" TPM3 "NEM1, TRK" ENSG00000143549 "Tropomyosin 3" P06753 1 154155308-154194648 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cancer-related genes, Disease variant, Nemaline myopathy, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 12 "skeletal muscle: 8593.7;tongue: 5867.8" "Cell type enhanced" "Detected in all" "monocytes: 1595.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Endothelial cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000261, HPA009066, HPA047089, HPA053624" Approved Approved "Actin filaments,Cytosol" NA NA 170000000 "Cluster 29: Non-specific - Unknown function" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 14: Neurons - Synaptic function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 45: Non-specific - Mixed function" 25 "Actin filaments" Cytosol "HPA000261: AB_1080339, HPA009066: AB_1080342, HPA047089: AB_2679928, HPA053624: AB_2682210" "unprognostic (1.64e-1)" "unprognostic (2.11e-2)" "unprognostic (3.01e-3)" "unprognostic (1.07e-1)" "unprognostic (2.39e-1)" "unprognostic (2.69e-3)" "prognostic unfavorable (6.73e-6)" "prognostic unfavorable (4.01e-4)" "unprognostic (2.80e-1)" "prognostic favorable (2.39e-5)" "prognostic unfavorable (3.65e-4)" "unprognostic (3.31e-2)" "prognostic unfavorable (3.12e-5)" "unprognostic (3.52e-2)" "unprognostic (1.67e-1)" "unprognostic (1.98e-2)" "unprognostic (1.00e-2)" TPM4 ENSG00000167460 "Tropomyosin 4" P67936 19 16067021-16103002 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Smooth muscle cells" "Low region specificity" "Detected in all" "CAB004685, HPA047089, HPA053624" Approved Approved "Actin filaments,Cytosol" NA NA 370000000 "Cluster 33: Non-specific - ATP binding" "Cluster 62: Connective tissue - ECM organization" "Cluster 25: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 45: Non-specific - Mixed function" 3 "Actin filaments" Cytosol "CAB004685: AB_425723, HPA047089: AB_2679928, HPA053624: AB_2682210" "unprognostic (1.27e-1)" "unprognostic (1.53e-2)" "unprognostic (3.62e-3)" "unprognostic (7.38e-3)" "unprognostic (3.80e-1)" "unprognostic (2.40e-2)" "unprognostic (3.11e-2)" "unprognostic (2.75e-3)" "unprognostic (1.38e-2)" "unprognostic (3.61e-1)" "prognostic unfavorable (3.07e-4)" "unprognostic (1.03e-1)" "prognostic unfavorable (1.26e-10)" "unprognostic (3.85e-2)" "unprognostic (2.25e-1)" "unprognostic (1.48e-1)" "unprognostic (1.78e-1)" TPMT ENSG00000137364 "Thiopurine S-methyltransferase" P51580 6 18128311-18155077 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 73.7;liver: 66.7;thyroid gland: 74.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 140.5;Proximal tubular cells: 270.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019851, HPA062364" Enhanced NA NA 39000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Non-specific - Mixed function" 1 "HPA019851: AB_1858213, HPA062364: " "unprognostic (6.24e-2)" "unprognostic (3.16e-2)" "unprognostic (5.46e-3)" "prognostic unfavorable (8.45e-5)" "unprognostic (4.98e-2)" "unprognostic (2.25e-1)" "unprognostic (8.16e-2)" "unprognostic (4.36e-3)" "unprognostic (9.62e-2)" "prognostic favorable (1.41e-4)" "unprognostic (4.49e-2)" "unprognostic (3.40e-2)" "prognostic favorable (1.10e-4)" "unprognostic (7.56e-2)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (8.39e-3)" TRIB3 "C20orf97, dJ1103G7.3, TRB3" ENSG00000101255 "Tribbles pseudokinase 3" Q96RU7 20 362835-397559 "Enzymes, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 78.5" "Cell type enhanced" "Detected in many" "Ductal cells: 45.6;Hepatocytes: 31.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA015272, HPA055442" Approved Supported Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 68: Non-specific - Protein processing" "Cluster 1: Neurons - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 45: Non-specific - Mixed function" 54 Nucleoplasm "HPA015272: AB_1858269, HPA055442: AB_2682818" "unprognostic (5.40e-2)" "unprognostic (1.89e-1)" "unprognostic (1.57e-1)" "unprognostic (2.25e-3)" "unprognostic (1.92e-1)" "prognostic unfavorable (1.70e-4)" "prognostic unfavorable (6.75e-5)" "unprognostic (1.52e-3)" "unprognostic (1.76e-1)" "unprognostic (1.24e-1)" "unprognostic (7.95e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (2.07e-13)" "unprognostic (7.62e-2)" "unprognostic (2.79e-2)" "unprognostic (2.31e-1)" "unprognostic (4.05e-3)" TRIM47 "GOA, RNF100" ENSG00000132481 "Tripartite motif containing 47" Q96LD4 17 75874164-75878581 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014933 Uncertain Supported Cytosol NA NA "Cluster 27: T-cells - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 19: Astrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 45: Non-specific - Mixed function" Cytosol "HPA014933: AB_10603219" "prognostic favorable (6.54e-4)" "unprognostic (8.42e-2)" "unprognostic (1.42e-1)" "unprognostic (2.42e-2)" "unprognostic (1.19e-2)" "unprognostic (4.07e-2)" "prognostic unfavorable (5.59e-5)" "unprognostic (2.08e-2)" "unprognostic (9.18e-3)" "unprognostic (2.74e-1)" "unprognostic (1.18e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (9.69e-5)" "unprognostic (3.94e-2)" "unprognostic (1.44e-2)" "unprognostic (3.01e-2)" "unprognostic (9.98e-2)" TRIM54 "MURF, MURF-3, RNF30" ENSG00000138100 "Tripartite motif containing 54" Q9BYV2 2 27282429-27307439 "Predicted intracellular proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "heart muscle: 206.3;skeletal muscle: 560.3;tongue: 170.3" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 124.0;Skeletal myocytes: 210.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 11.5" "Immune cell enriched" "Detected in single" 17 "NK-cell: 3.6" "Lineage enriched" "Detected in single" 17 "NK-cells: 3.6" "Cancer enhanced" "Detected in some" "Gastric cancer: 2.5" "Adipose visceral - Smooth muscle cells, Heart muscle - Cardiomyocytes, Kidney - Podocytes" "Region enhanced" "Detected in some" "amygdala: 3.1" HPA019690 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 53: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Non-specific - Mixed function" 151 "Plasma membrane, Cytosol" "HPA019690: AB_1858306" "unprognostic (6.98e-3)" "unprognostic (4.56e-3)" "unprognostic (3.22e-2)" "unprognostic (2.24e-2)" "unprognostic (1.58e-3)" "unprognostic (7.49e-2)" "unprognostic (1.25e-7)" "unprognostic (3.88e-3)" "unprognostic (2.29e-1)" "unprognostic (2.95e-1)" "unprognostic (2.56e-3)" "unprognostic (6.91e-2)" "prognostic unfavorable (6.46e-4)" "unprognostic (2.41e-2)" "unprognostic (3.19e-1)" "unprognostic (1.15e-1)" "unprognostic (6.92e-2)" TSPAN15 "NET-7, TM4SF15" ENSG00000099282 "Tetraspanin 15" O95858 10 69451465-69507666 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 109.7;Ductal cells: 110.5;Exocrine glandular cells: 113.7;Schwann cells: 102.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "MAIT T-cell: 19.5" "Lineage enriched" "Detected in many" 6 "T-cells: 19.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044657, HPA071160" Approved Approved "Nuclear bodies,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 4 "Nuclear bodies, Plasma membrane" "Vesicles, Cytosol" "HPA044657: AB_10967927, HPA071160: " "unprognostic (2.03e-1)" "unprognostic (1.28e-1)" "unprognostic (1.43e-1)" "unprognostic (1.48e-2)" "unprognostic (9.44e-3)" "unprognostic (6.81e-3)" "prognostic unfavorable (8.00e-4)" "unprognostic (2.23e-1)" "unprognostic (3.65e-1)" "unprognostic (2.76e-1)" "unprognostic (8.22e-3)" "unprognostic (2.36e-2)" "prognostic unfavorable (1.25e-4)" "unprognostic (8.49e-2)" "unprognostic (4.66e-2)" "unprognostic (6.34e-2)" "unprognostic (3.78e-3)" TSPAN3 "TM4-A, TM4SF8, TSPAN-3" ENSG00000140391 "Tetraspanin 3" O60637 15 77041404-77083984 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 608.3;Mesothelial cells: 489.5;Muller glia cells: 467.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "memory B-cell: 482.8;naive B-cell: 490.1;plasmacytoid DC: 313.6" "Group enriched" "Detected in all" 5 "B-cells: 490.1;dendritic cells: 313.6" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Lung - Alveolar cells type 2, Skin - Fibroblast_1, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015996 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 21: Non-specific - Metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Non-specific - Mixed function" "Nucleoplasm, Golgi apparatus" "HPA015996: AB_1858406" "unprognostic (5.94e-2)" "unprognostic (3.05e-1)" "unprognostic (7.32e-2)" "unprognostic (2.15e-2)" "unprognostic (4.16e-2)" "unprognostic (1.38e-1)" "unprognostic (1.92e-2)" "unprognostic (1.31e-1)" "unprognostic (1.09e-1)" "unprognostic (5.41e-3)" "unprognostic (3.51e-3)" "unprognostic (2.90e-2)" "unprognostic (2.11e-2)" "unprognostic (1.51e-1)" "unprognostic (1.75e-1)" "unprognostic (3.79e-3)" "unprognostic (1.35e-1)" TUBB3 "beta-4, CFEOM3, CFEOM3A, FEOM3" ENSG00000258947 "Tubulin beta 3 class III" Q13509 16 89921392-89938761 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 330.2" "Cell type enhanced" "Detected in many" "Astrocytes: 19.2;Ductal cells: 21.1;Excitatory neurons: 36.7;Exocrine glandular cells: 26.2;Gastric mucus-secreting cells: 21.2;Inhibitory neurons: 43.2;Late spermatids: 18.5;Oligodendrocyte precursor cells: 15.1;Pancreatic endocrine cells: 23.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "naive B-cell: 2.5" "Lineage enriched" "Detected in single" 9 "B-cells: 2.5" "Low cancer specificity" "Detected in all" "Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043640, HPA046280" Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA 89000000 "Cluster 33: Brain - Neuronal signaling" "Cluster 45: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 45: Non-specific - Mixed function" 4 Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (7.08e-2)" "unprognostic (3.37e-4)" "unprognostic (1.05e-1)" "unprognostic (1.06e-1)" "unprognostic (8.01e-2)" "unprognostic (3.12e-2)" "unprognostic (4.04e-3)" "unprognostic (1.12e-3)" "unprognostic (1.22e-2)" "unprognostic (6.06e-2)" "unprognostic (1.99e-2)" "unprognostic (1.38e-2)" "unprognostic (7.57e-2)" "unprognostic (1.27e-3)" "unprognostic (3.70e-2)" "unprognostic (3.05e-1)" "unprognostic (1.91e-2)" TXNDC17 "MGC14353, TRP14, TXNL5" ENSG00000129235 "Thioredoxin domain containing 17" Q9BRA2 17 6640985-6644541 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 177.8" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 730.8;Proximal tubular cells: 761.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022931 Approved NA NA 820000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 21: Non-specific - Metabolism" "Cluster 42: Non-specific - Unknown function" "Cluster 45: Non-specific - Mixed function" 4 "HPA022931: AB_1858479" "unprognostic (8.94e-2)" "unprognostic (6.03e-2)" "unprognostic (5.33e-2)" "unprognostic (2.97e-2)" "unprognostic (5.02e-2)" "unprognostic (5.06e-2)" "unprognostic (7.65e-3)" "unprognostic (3.88e-1)" "unprognostic (1.51e-2)" "unprognostic (2.21e-3)" "unprognostic (1.15e-2)" "unprognostic (9.97e-2)" "prognostic unfavorable (1.15e-5)" "unprognostic (8.86e-2)" "unprognostic (2.27e-1)" "unprognostic (3.09e-2)" "unprognostic (9.01e-2)" UBA1 "A1S9T, CFAP124, GXP1, POC20, UBE1, UBE1X" ENSG00000130985 "Ubiquitin like modifier activating enzyme 1" P22314 X 47190861-47215128 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Ligase "Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000289, HPA001506, CAB019435, CAB073410" Approved Supported Nucleoplasm,Cytosol NA NA 14000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 79: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 36: Non-specific - mRNA processing" "Cluster 45: Non-specific - Mixed function" 9 Nucleoplasm Cytosol "CAB019435: AB_2211440, CAB073410: , HPA000289: AB_1080443, HPA001506: AB_2756305" "unprognostic (7.18e-3)" "unprognostic (1.52e-1)" "unprognostic (7.54e-2)" "unprognostic (2.40e-1)" "unprognostic (9.29e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (6.10e-5)" "unprognostic (7.22e-2)" "unprognostic (2.42e-3)" "unprognostic (3.43e-2)" "unprognostic (8.50e-3)" "unprognostic (2.17e-3)" "unprognostic (1.85e-3)" "unprognostic (1.13e-1)" "unprognostic (5.38e-2)" "prognostic favorable (1.78e-4)" "unprognostic (1.21e-2)" UBD FAT10 ENSG00000213886 "Ubiquitin D" O15205 6 29555515-29559732 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 147.2" "Group enriched" "Detected in some" 8 "Ductal cells: 450.0;Exocrine glandular cells: 520.8;Pancreatic endocrine cells: 166.4" "Cancer enhanced" "Detected in all" "liver cancer: 75.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 22.4;thyroid cancer: 44.3" "Breast - T-cells, Pancreas - Ductal cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043710 Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 55: Lymphoma - Immune response" "Cluster 45: Non-specific - Mixed function" 3 Nucleoplasm "Nucleoli fibrillar center" "HPA043710: AB_2756303" "unprognostic (2.99e-3)" "unprognostic (4.16e-2)" "unprognostic (6.37e-2)" "unprognostic (2.61e-2)" "unprognostic (3.93e-2)" "unprognostic (3.53e-3)" "unprognostic (1.60e-1)" "unprognostic (9.47e-2)" "unprognostic (1.44e-2)" "prognostic favorable (7.35e-4)" "unprognostic (1.28e-2)" "unprognostic (6.43e-2)" "prognostic unfavorable (2.40e-5)" "unprognostic (4.04e-2)" "unprognostic (6.02e-2)" "unprognostic (8.40e-2)" "unprognostic (1.21e-2)" UBQLN4 "A1U, C1orf6, UBIN" ENSG00000160803 "Ubiquilin 4" Q9NRR5 1 156035299-156053798 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Autophagy, DNA damage, DNA repair" "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 9.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 9.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061797 Approved Supported Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 79: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 45: Non-specific - Nuclear processes" "Cluster 45: Non-specific - Mixed function" 20 Nucleoplasm "HPA061797: AB_2684613" "unprognostic (3.91e-2)" "unprognostic (2.01e-2)" "unprognostic (1.95e-1)" "unprognostic (1.29e-3)" "unprognostic (1.52e-2)" "unprognostic (6.75e-2)" "unprognostic (1.58e-3)" "unprognostic (5.48e-2)" "unprognostic (1.53e-1)" "unprognostic (1.32e-2)" "unprognostic (1.91e-2)" "unprognostic (1.01e-2)" "unprognostic (2.54e-2)" "unprognostic (7.25e-3)" "unprognostic (7.65e-2)" "unprognostic (4.73e-1)" "unprognostic (1.57e-1)" UGT2B28 ENSG00000135226 "UDP glucuronosyltransferase family 2 member B28" Q9BY64 4 69280475-69295050 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "breast: 193.8" "Cell type enriched" "Detected in single" 32 "Cholangiocytes: 11.4" "Cancer enriched" "Detected in single" 8 "breast cancer: 1.9" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "eosinophil: 1.3" "Lineage enriched" "Detected in single" 13 "granulocytes: 1.3" "Cancer enriched" "Detected in single" 9 "prostate cancer: 4.1" HPA045108 Uncertain "Intracellular and membrane" Enzyme NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 73: Breast - Lactation" "Cluster 60: Prostate cancer - Unknown function" "Cluster 45: Non-specific - Mixed function" "HPA045108: AB_2679218" "unprognostic (1.81e-1)" "unprognostic (1.40e-1)" "unprognostic (7.20e-3)" "unprognostic (1.51e-2)" "unprognostic (4.37e-5)" "unprognostic (9.79e-4)" USB1 "C16orf57, FLJ13154, HVSL1, Mpn1" ENSG00000103005 "U6 snRNA biogenesis phosphodiesterase 1" Q9BQ65 16 57999546-58021618 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Hydrolase, Lyase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041791, HPA059854" Approved Supported Nucleoplasm NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 49: Hindbrain - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 45: Non-specific - Mixed function" Nucleoplasm "HPA041791: AB_10793933, HPA059854: AB_2684143" "unprognostic (2.79e-1)" "unprognostic (3.84e-2)" "unprognostic (1.21e-2)" "unprognostic (9.65e-2)" "unprognostic (2.03e-1)" "unprognostic (2.23e-3)" "prognostic unfavorable (6.69e-7)" "unprognostic (4.30e-3)" "unprognostic (2.92e-1)" "unprognostic (4.98e-2)" "unprognostic (1.95e-1)" "unprognostic (1.78e-2)" "prognostic unfavorable (2.02e-4)" "unprognostic (2.18e-1)" "unprognostic (1.56e-1)" "unprognostic (1.06e-3)" "unprognostic (5.04e-2)" VAMP3 CEB ENSG00000049245 "Vesicle associated membrane protein 3" Q15836 1 7771296-7781432 "Cancer-related genes, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 260000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 37: Non-specific - mRNA processing" "Cluster 45: Non-specific - Mixed function" 46 "unprognostic (1.09e-2)" "unprognostic (4.03e-1)" "unprognostic (3.39e-3)" "unprognostic (2.95e-1)" "unprognostic (9.15e-3)" "unprognostic (3.86e-3)" "unprognostic (9.49e-3)" "unprognostic (2.00e-1)" "unprognostic (7.16e-2)" "unprognostic (2.36e-1)" "unprognostic (1.83e-3)" "unprognostic (2.17e-1)" "prognostic favorable (2.36e-4)" "unprognostic (1.02e-1)" "unprognostic (2.85e-1)" "unprognostic (9.52e-2)" "unprognostic (3.30e-2)" VAMP8 "EDB, VAMP-8" ENSG00000118640 "Vesicle associated membrane protein 8" Q9BV40 2 85561562-85582031 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiviral defense, Autophagy, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 1201.5;Proximal enterocytes: 1181.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Breast - Breast glandular cells, Heart muscle - Macrophages, Skeletal muscle - Macrophages, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006882, HPA007215, CAB037132, CAB037147" Enhanced Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA 220000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 45: Non-specific - Mixed function" 3 "Golgi apparatus, Plasma membrane" Nucleoplasm "CAB037132: AB_1080547, CAB037147: AB_1080544, HPA006882: AB_1858716, HPA007215: " "unprognostic (1.00e-1)" "unprognostic (1.16e-1)" "unprognostic (7.46e-3)" "unprognostic (1.13e-1)" "unprognostic (7.33e-2)" "unprognostic (1.31e-1)" "unprognostic (1.76e-2)" "unprognostic (3.79e-3)" "unprognostic (3.83e-2)" "unprognostic (4.15e-1)" "unprognostic (2.74e-2)" "unprognostic (8.62e-2)" "unprognostic (1.57e-3)" "unprognostic (1.92e-2)" "unprognostic (2.16e-1)" "prognostic favorable (8.07e-9)" "prognostic favorable (1.59e-6)" VDAC2 ENSG00000165637 "Voltage dependent anion channel 2" P45880 10 75210154-75231448 "Predicted intracellular proteins, Transporters" "Ion transport, Transport" Porin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043475 Enhanced Supported Mitochondria NA NA 490000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 35: Non-specific - Mitochondria" "Cluster 21: Non-specific - Metabolism" "Cluster 52: Non-specific - Mitochondria" "Cluster 45: Non-specific - Mixed function" 19 Mitochondria "HPA043475: AB_10795615" "unprognostic (1.01e-2)" "unprognostic (1.22e-1)" "unprognostic (9.47e-2)" "unprognostic (9.00e-3)" "unprognostic (5.74e-2)" "prognostic unfavorable (4.51e-4)" "prognostic unfavorable (4.55e-4)" "unprognostic (1.83e-3)" "unprognostic (5.89e-2)" "unprognostic (2.45e-1)" "unprognostic (2.02e-2)" "unprognostic (1.56e-2)" "unprognostic (4.27e-2)" "unprognostic (1.40e-1)" "unprognostic (1.65e-1)" "unprognostic (6.28e-2)" "unprognostic (1.34e-2)" VEZT DKFZP761C241 ENSG00000028203 "Vezatin, adherens junctions transmembrane protein" Q9HBM0 12 95217746-95302799 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004811, HPA017066" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 3: Non-specific - Unknown function" "Cluster 2: Neurons - Nucleosome" "Cluster 38: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" Nucleoplasm Cytosol "HPA004811: AB_1080563, HPA017066: AB_1858742" "unprognostic (3.91e-1)" "unprognostic (6.34e-3)" "unprognostic (3.48e-2)" "unprognostic (1.64e-1)" "unprognostic (1.47e-1)" "unprognostic (1.31e-2)" "prognostic unfavorable (1.71e-4)" "unprognostic (2.28e-1)" "unprognostic (9.93e-2)" "unprognostic (4.18e-1)" "unprognostic (1.10e-3)" "unprognostic (3.37e-3)" "prognostic unfavorable (1.93e-5)" "prognostic unfavorable (3.68e-4)" "unprognostic (1.51e-1)" "unprognostic (4.06e-1)" "unprognostic (5.02e-2)" VNN1 Tiff66 ENSG00000112299 "Vanin 1" O95497 6 132680849-132714055 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "gallbladder: 86.2;intestine: 132.5;liver: 212.1" "Cell type enhanced" "Detected in many" "Cholangiocytes: 55.3;Ductal cells: 259.1;Exocrine glandular cells: 71.0;Hepatocytes: 67.5;monocytes: 181.9;Proximal enterocytes: 52.0" "Cancer enhanced" "Detected in many" "liver cancer: 41.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 13.7;non-classical monocyte: 12.0" "Group enriched" "Detected in many" 80 "dendritic cells: 5.0;granulocytes: 8.5;monocytes: 13.7" "Cancer enhanced" "Detected in many" "liver cancer: 13.2;thyroid cancer: 9.6" "Adipose subcutaneous - Macrophages, Colon - Macrophages, Kidney - Proximal tubular cells, Lung - Neutrophil_2" "Region enhanced" "Detected in single" "white matter: 2.4" "Not detected" "Not detected" "HPA046103, HPA064145" Approved Approved Vesicles "Intracellular and membrane" Enzyme NA NA 980000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 6: Non-specific - Immune response" "Cluster 7: Liver cancer - Metabolism" "Cluster 45: Non-specific - Mixed function" Vesicles "HPA046103: , HPA064145: AB_2685197" "unprognostic (9.53e-2)" "unprognostic (5.01e-2)" "unprognostic (9.95e-2)" "unprognostic (1.35e-3)" "unprognostic (6.11e-2)" "unprognostic (1.16e-2)" "unprognostic (2.20e-1)" "unprognostic (4.20e-2)" "unprognostic (2.06e-2)" "unprognostic (3.64e-2)" "unprognostic (2.11e-2)" "unprognostic (4.62e-1)" "prognostic unfavorable (2.52e-4)" "unprognostic (2.26e-2)" "unprognostic (4.42e-2)" "unprognostic (2.16e-1)" "unprognostic (2.34e-1)" VSIG2 "CTH, CTXL" ENSG00000019102 "V-set and immunoglobulin domain containing 2" Q96IQ7 11 124747474-124752255 "Predicted membrane proteins" "Lipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "stomach 1: 602.9" "Group enriched" "Detected in many" 4 "Club cells: 178.1;Distal enterocytes: 614.6;Gastric mucus-secreting cells: 612.0;Intestinal goblet cells: 227.6;Paneth cells: 362.0" "Cancer enhanced" "Detected in many" "urothelial cancer: 87.4" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Gastric cancer: 19.0" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA035919, HPA050147" Enhanced Approved Nucleoplasm NA NA 78000 "Cluster 45: Intestine - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Non-specific - Mixed function" Nucleoplasm "HPA035919: AB_10669981, HPA050147: AB_2681032" "unprognostic (1.64e-3)" "unprognostic (1.21e-1)" "unprognostic (1.10e-2)" "unprognostic (1.90e-1)" "unprognostic (2.00e-1)" "unprognostic (2.18e-3)" "unprognostic (2.16e-1)" "unprognostic (2.22e-2)" "unprognostic (3.47e-3)" "unprognostic (2.02e-1)" "unprognostic (6.01e-2)" "unprognostic (2.78e-2)" "unprognostic (2.99e-2)" "unprognostic (2.61e-1)" "unprognostic (1.95e-1)" "unprognostic (1.87e-1)" "unprognostic (1.36e-2)" WNT7B ENSG00000188064 "Wnt family member 7B" P56706 22 45920366-45977162 "Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.3;esophagus: 12.0;skin 1: 17.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 17.0;Basal keratinocytes: 30.4;Basal respiratory cells: 14.8;Basal squamous epithelial cells: 37.0;Club cells: 36.9;Squamous epithelial cells: 18.7;Suprabasal keratinocytes: 18.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Prostate - Urothelial cells, Skin - Keratinocyte (other), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 80: Non-specific - Endocytosis" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" "unprognostic (2.02e-3)" "unprognostic (7.83e-3)" "unprognostic (8.51e-2)" "unprognostic (2.93e-2)" "unprognostic (3.26e-2)" "unprognostic (1.31e-1)" "unprognostic (1.85e-2)" "unprognostic (2.74e-1)" "unprognostic (2.01e-1)" "unprognostic (4.05e-2)" "unprognostic (3.85e-3)" "unprognostic (1.69e-2)" "unprognostic (8.58e-4)" "unprognostic (1.90e-1)" "unprognostic (6.73e-2)" "unprognostic (1.36e-1)" "unprognostic (1.22e-2)" WSB2 "MGC10210, SBA2" ENSG00000176871 "WD repeat and SOCS box containing 2" Q9NYS7 12 118032687-118062430 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052606 Uncertain NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 38: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" "HPA052606: AB_2681882" "unprognostic (5.02e-3)" "unprognostic (4.57e-2)" "unprognostic (4.85e-2)" "unprognostic (1.25e-1)" "unprognostic (1.07e-1)" "unprognostic (4.91e-2)" "prognostic unfavorable (2.42e-5)" "unprognostic (2.42e-3)" "unprognostic (4.66e-3)" "unprognostic (7.29e-2)" "unprognostic (1.05e-1)" "unprognostic (2.93e-1)" "unprognostic (4.05e-1)" "unprognostic (2.92e-1)" "unprognostic (2.66e-1)" "unprognostic (2.79e-1)" "unprognostic (2.42e-2)" XRCC4 ENSG00000152422 "X-ray repair cross complementing 4" Q13426 5 83077498-83353787 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 75.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006801, HPA051538" Supported Enhanced Nucleoplasm NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 45: Non-specific - Mixed function" 14 Nucleoplasm "HPA006801: AB_1858899, HPA051538: AB_2681526" "prognostic unfavorable (1.80e-5)" "unprognostic (3.05e-2)" "unprognostic (5.12e-2)" "unprognostic (3.91e-3)" "unprognostic (1.55e-1)" "unprognostic (1.69e-1)" "unprognostic (1.44e-3)" "unprognostic (2.23e-2)" "unprognostic (2.19e-2)" "unprognostic (5.77e-2)" "unprognostic (2.38e-2)" "unprognostic (8.24e-2)" "unprognostic (4.46e-2)" "unprognostic (1.79e-1)" "unprognostic (1.97e-1)" "unprognostic (2.34e-1)" "unprognostic (6.91e-2)" YDJC ENSG00000161179 "YdjC chitooligosaccharide deacetylase homolog" A8MPS7 22 21628089-21630064 "Predicted intracellular proteins" "Carbohydrate metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001501 Approved "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 14: Neurons - Synaptic function" "Cluster 66: Non-specific - Mitochondria" "Cluster 45: Non-specific - Mixed function" "Golgi apparatus, Vesicles" Cytosol "HPA001501: " "unprognostic (5.34e-2)" "unprognostic (2.30e-1)" "unprognostic (3.96e-1)" "unprognostic (2.29e-1)" "unprognostic (2.31e-2)" "unprognostic (1.82e-1)" "prognostic unfavorable (9.84e-4)" "unprognostic (9.35e-2)" "unprognostic (7.08e-2)" "unprognostic (8.09e-3)" "unprognostic (1.24e-1)" "unprognostic (9.86e-2)" "unprognostic (4.90e-3)" "unprognostic (1.07e-1)" "unprognostic (2.25e-1)" "unprognostic (9.60e-2)" "prognostic favorable (8.98e-5)" YKT6 ENSG00000106636 "YKT6 v-SNARE homolog" O15498 7 44200959-44214294 "Metabolic proteins, Predicted intracellular proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030817, HPA030818" Approved Approved Mitochondria,Cytosol No No 23000 "Cluster 45: Eosinophils - Unknown function" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 67: Non-specific - Unknown function" "Cluster 45: Non-specific - Mixed function" Cytosol Mitochondria "HPA030817: AB_10599828, HPA030818: AB_10602102" "unprognostic (1.25e-1)" "unprognostic (7.35e-3)" "unprognostic (1.30e-3)" "unprognostic (7.80e-3)" "unprognostic (7.45e-3)" "prognostic unfavorable (4.64e-4)" "prognostic unfavorable (1.02e-4)" "unprognostic (3.14e-2)" "unprognostic (2.03e-1)" "unprognostic (8.77e-3)" "unprognostic (1.99e-1)" "unprognostic (1.17e-1)" "unprognostic (8.65e-2)" "unprognostic (1.63e-1)" "unprognostic (2.01e-2)" "unprognostic (1.34e-2)" "unprognostic (7.66e-3)" YWHAB YWHAA ENSG00000166913 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta" P31946 20 44885702-44908532 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003759, HPA007925, HPA011212, CAB080288, CAB080290" Enhanced Supported Cytosol NA NA 97000000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 45: Non-specific - Mixed function" 78 Cytosol "CAB003759: AB_289588, CAB080288: , CAB080290: , HPA007925: AB_1844340, HPA011212: AB_1844334" "prognostic unfavorable (9.18e-4)" "unprognostic (1.48e-1)" "unprognostic (9.06e-2)" "prognostic unfavorable (5.46e-4)" "unprognostic (3.80e-1)" "prognostic unfavorable (6.14e-4)" "prognostic unfavorable (1.91e-6)" "prognostic unfavorable (6.01e-4)" "unprognostic (8.92e-2)" "unprognostic (2.01e-1)" "unprognostic (1.53e-2)" "unprognostic (2.35e-1)" "prognostic favorable (2.52e-5)" "unprognostic (6.72e-2)" "unprognostic (2.40e-1)" "unprognostic (6.60e-3)" "unprognostic (8.59e-2)" YWHAZ "14-3-3-zeta, KCIP-1, YWHAD" ENSG00000164924 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta" P63104 8 100916523-100953388 "Plasma proteins, Predicted intracellular proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 2282.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005065 Approved NA NA 320000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 14: Neurons - Synaptic function" "Cluster 40: Non-specific - Unknown function" "Cluster 45: Non-specific - Mixed function" 128 "CAB005065: AB_2218378" "unprognostic (4.70e-3)" "unprognostic (7.38e-3)" "unprognostic (8.09e-2)" "prognostic unfavorable (3.91e-4)" "unprognostic (1.83e-3)" "unprognostic (2.00e-2)" "prognostic unfavorable (2.28e-5)" "prognostic unfavorable (3.93e-4)" "unprognostic (1.65e-1)" "unprognostic (3.72e-1)" "prognostic unfavorable (1.20e-5)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.03e-6)" "unprognostic (1.02e-1)" "unprognostic (1.69e-1)" "unprognostic (1.20e-1)" "unprognostic (1.49e-1)" ZNF780A ZNF780 ENSG00000197782 "Zinc finger protein 780A" O75290 19 40069152-40090943 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 40.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA003311 Uncertain Approved Nucleoplasm,Centrosome NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" 1 Nucleoplasm Centrosome "HPA003311: AB_1080757" "unprognostic (1.92e-1)" "unprognostic (9.25e-2)" "unprognostic (7.38e-2)" "unprognostic (2.27e-2)" "unprognostic (1.53e-2)" "unprognostic (8.95e-2)" "unprognostic (1.30e-1)" "unprognostic (1.10e-1)" "unprognostic (2.14e-2)" "unprognostic (1.46e-2)" "unprognostic (1.19e-2)" "unprognostic (2.17e-1)" "unprognostic (4.47e-3)" "unprognostic (1.13e-1)" "unprognostic (9.49e-2)" "unprognostic (4.91e-2)" "prognostic favorable (9.30e-4)" ZSWIM4 FLJ12221 ENSG00000132003 "Zinc finger SWIM-type containing 4" Q9H7M6 19 13795443-13832254 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 25.8;Mucus glandular cells: 38.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042084 Uncertain NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 18: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" "HPA042084: AB_10795392" "unprognostic (3.29e-2)" "unprognostic (4.07e-1)" "unprognostic (4.15e-2)" "unprognostic (1.41e-3)" "unprognostic (4.78e-2)" "unprognostic (1.34e-3)" "unprognostic (4.25e-3)" "unprognostic (6.14e-2)" "unprognostic (5.36e-2)" "unprognostic (1.56e-2)" "unprognostic (1.78e-1)" "unprognostic (6.15e-2)" "prognostic unfavorable (7.85e-5)" "unprognostic (3.47e-1)" "unprognostic (4.95e-1)" "unprognostic (1.86e-1)" "unprognostic (8.63e-2)"