Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific nTPM"	"RNA single cell type specificity"	"RNA single cell type distribution"	"RNA single cell type specificity score"	"RNA single cell type specific nTPM"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific FPKM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific nTPM"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific nTPM"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific nTPM"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific nTPM"	"RNA tissue cell type enrichment"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific nTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific nTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"Secretome function"	"CCD Protein"	"CCD Transcript"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Blood expression cluster"	"Tissue expression cluster"	"Brain expression cluster"	"Cell line expression cluster"	"Single cell expression cluster"	Interactions	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Pathology prognostics - Breast cancer"	"Pathology prognostics - Cervical cancer"	"Pathology prognostics - Colorectal cancer"	"Pathology prognostics - Endometrial cancer"	"Pathology prognostics - Glioma"	"Pathology prognostics - Head and neck cancer"	"Pathology prognostics - Liver cancer"	"Pathology prognostics - Lung cancer"	"Pathology prognostics - Melanoma"	"Pathology prognostics - Ovarian cancer"	"Pathology prognostics - Pancreatic cancer"	"Pathology prognostics - Prostate cancer"	"Pathology prognostics - Renal cancer"	"Pathology prognostics - Stomach cancer"	"Pathology prognostics - Testis cancer"	"Pathology prognostics - Thyroid cancer"	"Pathology prognostics - Urothelial cancer"
CALR	"cC1qR, CRT, FLJ26680, RO, SSA"	ENSG00000179218	Calreticulin	P27797	19	12938578-12944489	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters"		Chaperone	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Extravillous trophoblasts: 1893.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB001513, HPA002242, CAB019952, CAB079775, CAB080301"	Enhanced		Supported	"Endoplasmic reticulum"	"Intracellular and membrane"	Other	NA	NA		210000000	"Cluster 13: Non-specific - Mitochondria"	"Cluster 53: Non-specific - Glycosylation"	"Cluster 21: Non-specific - Metabolism"	"Cluster 63: Non-specific - Protein processing"	"Cluster 77: Plasma cells - Protein processing"	63	"Endoplasmic reticulum"		"CAB001513: , CAB019952: AB_2069792, CAB079775: AB_303403, CAB080301: , HPA002242: AB_1078384"	"unprognostic (1.49e-1)"	"unprognostic (1.57e-1)"	"unprognostic (8.46e-2)"	"unprognostic (4.25e-2)"	"unprognostic (9.44e-3)"	"unprognostic (6.93e-2)"	"unprognostic (2.47e-2)"	"unprognostic (4.60e-2)"	"unprognostic (2.61e-1)"	"prognostic favorable (1.10e-4)"	"unprognostic (2.07e-1)"	"unprognostic (3.76e-1)"	"prognostic unfavorable (1.11e-16)"	"unprognostic (2.37e-1)"	"unprognostic (1.96e-1)"	"unprognostic (1.37e-1)"	"unprognostic (5.27e-2)"
DLST	"DLTS, KGD2, OGDC-E2"	ENSG00000119689	"Dihydrolipoamide S-succinyltransferase"	P36957	14	74881891-74903743	"Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Tricarboxylic acid cycle"	"Acyltransferase, Transferase"	"Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Heart muscle - Cardiomyocytes"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA003010	Supported		Supported	Nucleoplasm,Mitochondria,Cytosol			NA	NA		70000	"Cluster 41: Basophils - Unknown function"	"Cluster 35: Non-specific - Mitochondria"	"Cluster 42: Choroid plexus - Mitochondria"	"Cluster 30: Non-specific - Gene expression regulation"	"Cluster 56: Proximal tubular cells - Amino acid metabolism"	55	Nucleoplasm	"Mitochondria, Cytosol"	"HPA003010: AB_1078679"	"unprognostic (1.62e-1)"	"unprognostic (3.01e-1)"	"unprognostic (2.45e-3)"	"unprognostic (6.36e-2)"	"unprognostic (1.29e-1)"	"unprognostic (1.21e-2)"	"unprognostic (1.16e-1)"	"unprognostic (5.83e-2)"	"unprognostic (3.03e-1)"	"unprognostic (1.37e-1)"	"unprognostic (2.12e-2)"	"unprognostic (1.18e-1)"	"prognostic favorable (1.13e-12)"	"unprognostic (3.29e-2)"	"unprognostic (1.08e-1)"	"unprognostic (1.66e-1)"	"unprognostic (4.55e-3)"
KLK6	"Bssp, Klk7, neurosin, PRSS18, PRSS9"	ENSG00000167755	"Kallikrein related peptidase 6"	Q92876	19	50958631-50969673	"Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins"		"Hydrolase, Protease, Serine protease"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in many"	5	"brain: 457.6"	"Cell type enhanced"	"Detected in some"		"Breast glandular cells: 25.1;Mucus glandular cells: 65.5;Oligodendrocytes: 81.8;Salivary duct cells: 23.5;Secretory cells: 97.3"	"Cancer enhanced"	"Detected in many"		"ovarian cancer: 131.3"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enhanced"	"Detected in many"		"Bile duct cancer: 650.6;Gallbladder cancer: 349.4"	"Adipose visceral - Mesothelial cells, Kidney - Podocytes"	"Region enhanced"	"Detected in all"		"pons and medulla: 167.9"	"Region enhanced"	"Detected in all"		"spinal cord: 448.7"	HPA051837			Supported	"Nucleoplasm,Nuclear membrane,Cytokinetic bridge"	"Secreted in other tissues"	Enzyme	Yes	No		10000000		"Cluster 9: Oligodendrocytes - Myelination"	"Cluster 30: White matter - Myelination"	"Cluster 53: Squamous epithelial cells - Keratinization"	"Cluster 37: Glandular & Luminal cells - Unknown function"	100	Nucleoplasm	"Nuclear membrane, Cytokinetic bridge"	"HPA051837: "	"unprognostic (7.30e-2)"	"unprognostic (3.32e-1)"	"unprognostic (6.58e-2)"	"prognostic unfavorable (1.38e-5)"	"unprognostic (1.10e-1)"	"unprognostic (2.31e-1)"		"prognostic unfavorable (8.85e-4)"	"unprognostic (3.02e-1)"	"unprognostic (2.46e-1)"	"prognostic unfavorable (7.82e-4)"	"unprognostic (4.45e-1)"	"unprognostic (2.72e-2)"	"unprognostic (1.31e-1)"	"unprognostic (2.46e-1)"	"unprognostic (9.07e-2)"	"prognostic unfavorable (1.27e-4)"
NEK7		ENSG00000151414	"NIMA related kinase 7"	Q8TDX7	1	198156994-198322420	"Enzymes, Predicted intracellular proteins, Transporters"		"Kinase, Serine/threonine-protein kinase, Transferase"		"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"heart muscle: 135.4"	"Cell type enhanced"	"Detected in all"		"Cardiomyocytes: 232.5;Oligodendrocytes: 142.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA015520, HPA018193"	Approved		Supported	Nucleoplasm			Yes	No			"Cluster 1: T-cells - Unknown function"	"Cluster 30: Heart muscle - Heart development"	"Cluster 39: Astrocytes - Mixed function"	"Cluster 64: Connective tissue cells - ECM organization"	"Cluster 32: Smooth muscle cells - Muscle contraction"	65	Nucleoplasm		"HPA015520: AB_1854371, HPA018193: AB_1854372"	"unprognostic (2.08e-1)"	"unprognostic (2.98e-2)"	"unprognostic (1.65e-1)"	"unprognostic (5.38e-2)"	"unprognostic (4.26e-2)"	"unprognostic (3.00e-2)"	"unprognostic (2.14e-2)"	"unprognostic (5.47e-2)"	"unprognostic (4.77e-2)"	"unprognostic (3.21e-1)"	"unprognostic (1.46e-3)"	"unprognostic (2.82e-1)"	"unprognostic (1.13e-2)"	"unprognostic (1.26e-2)"	"unprognostic (1.74e-1)"	"unprognostic (2.05e-2)"	"unprognostic (1.56e-1)"