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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
No data
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
36.7
nTPM
HPA Brain:
48.5
nTPM
GTEx:
36.7
nTPM
Pig:
7.2
nTPM
Mouse:
0.7
nTPM
Allen mouse:
0.0
Expression energy
MIDBRAIN - HPA Brain RNA-seq
Max nTPM
48.5
Sample id
Sample description
nTPM
Cuneiform nucleus nTPM: 38.2
2586
Male, age 75, left hemisphere
53.7
2666
Male, age 74, left hemisphere
51.3
1830
Male, age 51, unknown
43.2
2019
Male, age 18, unknown
39.0
1870
Female, age 42, unknown
37.4
1833
Male, age 53, unknown
35.8
2828
Female, age 72, unknown
35.3
1827
Male, age 72, unknown
32.3
2411
Female, age 72, unknown
30.5
2219
Male, age 76, both hemispheres
23.4
Dorsal raphe nucleus nTPM: 38.0
2750
Male, age 76, both hemispheres
52.4
2047
Male, age 72, unknown
42.4
1828
Male, age 53, unknown
34.4
2298
Female, age 72, unknown
30.9
2016
Female, age 72, unknown
30.0
Inferior colliculus nTPM: 29.0
2849
Male, age 72, unknown
30.2
1890
Male, age 53, unknown
29.4
1848
Female, age 42, unknown
28.5
2097
Female, age 72, unknown
27.8
Median raphe nucleus nTPM: 48.5
2220
Male, age 76, midline
48.5
Periaquaductal grey, anterior nTPM: 37.4
1795
Male, age 51, unknown
41.6
2502
Female, age 75, unknown
35.5
1947
Male, age 18, unknown
34.9
Periaquaductal grey, dorsal nTPM: 32.5
2850
Male, age 76, both hemispheres
41.8
1831
Male, age 72, unknown
34.9
2464
Female, age 72, unknown
28.5
1840
Male, age 53, unknown
24.7
Periaquaductal grey, lateral nTPM: 40.2
2140
Male, age 76, both hemispheres
47.3
2053
Male, age 18, unknown
39.9
2272
Male, age 74, both hemispheres
33.3
Pretectal area nTPM: 29.9
2316
Male, age 76, right hemisphere
44.4
1817
Female, age 42, unknown
40.1
2224
Female, age 72, unknown
37.2
2825
Male, age 18, unknown
33.2
2007
Male, age 72, unknown
29.8
1815
Male, age 53, unknown
27.7
2667
Female, age 75, unknown
27.7
1944
Female, age 72, unknown
25.0
2407
Male, age 75, both hemispheres
24.6
1816
Male, age 51, unknown
21.6
2273
Male, age 74, both hemispheres
17.4
Red nucleus nTPM: 39.8
2588
Male, age 74, left hemisphere
48.9
2823
Male, age 76, right hemisphere
46.8
2227
Male, age 72, unknown
44.8
1904
Male, age 53, unknown
42.0
2769
Male, age 72, unknown
40.8
1821
Female, age 72, unknown
40.4
1954
Female, age 42, unknown
39.4
2785
Male, age 18, unknown
39.3
2725
Female, age 75, unknown
39.0
2584
Male, age 75, left hemisphere
35.2
1865
Male, age 51, unknown
34.6
2503
Female, age 72, unknown
26.1
Substantia nigra nTPM: 37.1
2665
Male, age 74, both hemispheres
51.3
2699
Male, age 18, unknown
45.7
1851
Male, age 51, unknown
43.7
1941
Male, age 53, unknown
38.9
2409
Female, age 72, unknown
34.4
1889
Female, age 72, unknown
32.4
2583
Male, age 75, right hemisphere
31.6
1916
Female, age 42, unknown
31.5
2590
Female, age 75, unknown
31.4
2241
Male, age 72, unknown
29.8
Superior colliculus nTPM: 28.1
2668
Female, age 75, unknown
35.6
2087
Female, age 72, unknown
35.0
1839
Male, age 51, unknown
30.6
2587
Male, age 74, left hemisphere
28.6
1796
Male, age 53, unknown
27.9
1895
Male, age 76, right hemisphere
27.6
2664
Male, age 75, both hemispheres
26.2
1913
Female, age 42, unknown
25.8
1995
Male, age 72, unknown
24.6
2261
Male, age 18, unknown
19.5
Ventral tegmental area nTPM: 44.5
2218
Male, age 76, both hemispheres
61.0
2021
Male, age 53, unknown
56.0
2223
Female, age 72, unknown
45.5
1942
Male, age 51, unknown
38.3
1915
Female, age 42, unknown
37.4
2410
Female, age 72, unknown
29.1
MIDBRAIN - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Average nTPM
36.7
GTEx sample id
Sample description
nTPM
Brain - Substantia nigra Average nTPM: 36.7
Samples: 139
Max nTPM: 141.7
Min nTPM: 8.9
Std nTPM: 22.5
Median nTPM: 29.9
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Average nTPM
0.7
Mouse sample
Sample description
nTPM
Midbrain nTPM: 0.7
Samples: 4
Max nTPM: 1.0
Min nTPM: 0.3
Sample A
Male
1.0
Sample B
Male
0.3
Sample C
Female
0.9
Sample D
Female
0.5
MIDBRAIN - Allen Mouse ISHi
In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.