CEREBRAL CORTEX - Expression summary
Protein expression
Cerebral cortexi
h
m
l
n
Endothelial cells: Low
Glial cells: Not detected
Neuronal cells: Not detected
Neuropil: Medium
RNA expressioni
Consensus:29.4 nTPM
HPA:20.2 nTPM
HPA Brain:52.6 nTPM
HPA PFC Brain:15.5 nTPM
GTEx:29.4 nTPM
FANTOM5:47.7 Scaled Tags Per Million
Pig:51.8 nTPM
Mouse:36.0 nTPM
Allen mouse:0.5 Expression energy

CEREBRAL CORTEX - Antibody stainingi
Antibody HPA056169
Endothelial cells Low
Glial cells Not detected
Neuronal cells Not detected
Neuropil Medium



CEREBRAL CORTEX - HPA RNA-seqi
Average nTPM 20.2
N/A
Male, age 5
Cerebral cortex sample 48
nTPM: 26.4
overview
Female, age 40
Cerebral cortex sample 105
nTPM: 25.1
Cell types%
Neuronal cells:
35

Glial cells and endothelial cells:
65
overview
Male, age 70
Cerebral cortex sample 106
nTPM: 9.3
Cell types%
Neuronal cells:
35

Glial cells and endothelial cells:
65

CEREBRAL CORTEX - HPA Brain RNA-seq
Max nTPM 52.6
Sample id Sample description nTPM
Angular gyrus
nTPM: 26.4
2221 Female, age 67, right hemisphere 40.9
2602 Female, age 94, right hemisphere 30.5
2260 Female, age 72, left hemisphere 29.4
2265 Female, age 91, left hemisphere 24.4
1866 Male, age 76, both hemispheres 23.8
1790 Male, age 76, right hemisphere 23.4
2722 Male, age 61, left hemisphere 19.5
2103 Male, age 75, left hemisphere 19.2
Anterior cingulate cortex, supragenual-dorsal
nTPM: 27.5
2478 Female, age 67, right hemisphere 30.3
2547 Male, age 74, left hemisphere 29.1
2472 Male, age 75, left hemisphere 28.2
2342 Female, age 94, right hemisphere 27.2
1896 Female, age 85, right hemisphere 23.1
Anterior cingulate cortex, supragenual-ventral
nTPM: 25.5
2538 Male, age 75, left hemisphere 29.9
1950 Female, age 85, right hemisphere 28.6
1755 Female, age 94, right hemisphere 24.4
1761 Male, age 74, left hemisphere 23.5
2479 Female, age 67, right hemisphere 20.9
Anterior insular cortex, dorsal
nTPM: 26.8
2506 Female, age 94, right hemisphere 35.9
2001 Male, age 76, right hemisphere 29.9
2235 Female, age 91, right hemisphere 21.6
2670 Male, age 75, left hemisphere 19.9
Anterior insular cortex, ventral
nTPM: 33.5
2757 Male, age 61, right hemisphere 40.8
2507 Female, age 94, left hemisphere 38.0
2262 Female, age 67, right hemisphere 35.8
1852 Male, age 76, left hemisphere 35.5
1925 Female, age 91, left hemisphere 32.6
2596 Male, age 75, left hemisphere 18.1
Area parastriata, inferior
nTPM: 17.0
1789 Male, age 76, right hemisphere 24.4
2268 Male, age 61, right hemisphere 23.9
1758 Female, age 72, right hemisphere 18.6
1760 Female, age 67, left hemisphere 18.2
2509 Female, age 94, left hemisphere 13.2
2421 Female, age 91, left hemisphere 10.8
2234 Male, age 75, left hemisphere 10.2
Area parastriata, parietal
nTPM: 21.6
2233 Male, age 61, right hemisphere 24.6
1785 Male, age 76, right hemisphere 24.3
2236 Female, age 91, left hemisphere 23.4
2680 Female, age 94, right hemisphere 22.3
2420 Male, age 75, left hemisphere 13.2
Area parastriata, superior
nTPM: 33.0
2881 Male, age 76, left hemisphere 95.8
1773 Female, age 91, left hemisphere 26.4
2435 Male, age 61, left hemisphere 25.5
2604 Female, age 94, right hemisphere 18.7
2419 Male, age 75, right hemisphere 16.6
2684 Female, age 67, left hemisphere 14.8
Area parastriata, temporal
nTPM: 24.2
1804 Male, age 76, right hemisphere 28.4
2267 Male, age 61, right hemisphere 27.7
2471 Male, age 75, left hemisphere 23.5
2424 Female, age 67, left hemisphere 21.3
2681 Female, age 94, right hemisphere 19.9
Area striata
nTPM: 15.4
2679 Female, age 94, right hemisphere 18.6
2002 Female, age 91, right hemisphere 15.4
1753 Female, age 72, right hemisphere 15.1
2427 Female, age 91, left hemisphere 15.1
2417 Male, age 61, right hemisphere 14.3
1884 Male, age 76, left hemisphere 13.8
Claustrum
nTPM: 40.2
2568 Male, age 61, both hemispheres 52.1
2198 Male, age 80, both hemispheres 51.4
2645 Female, age 72, unknown 45.6
2491 Male, age 75, both hemispheres 42.4
2284 Female, age 91, both hemispheres 38.6
1956 Male, age 74, unknown 37.7
2196 Female, age 79, unknown 36.6
2292 Female, age 85, both hemispheres 30.4
2392 Female, age 94, both hemispheres 27.0
Frontal eye field
nTPM: 24.6
2761 Female, age 94, left hemisphere 26.3
2543 Male, age 74, left hemisphere 25.5
2147 Male, age 61, left hemisphere 23.9
2441 Male, age 75, left hemisphere 22.6
Frontal operculum
nTPM: 23.5
2781 Female, age 85, right hemisphere 27.7
2030 Male, age 61, right hemisphere 25.8
2348 Male, age 75, left hemisphere 16.9
Fusiform gyrus
nTPM: 33.4
2784 Female, age 85, left hemisphere 53.0
2112 Male, age 80, both hemispheres 43.8
1807 Male, age 76, left hemisphere 40.8
2617 Female, age 94, left hemisphere 38.1
2074 Female, age 91, left hemisphere 24.1
2433 Female, age 72, left hemisphere 17.3
2431 Male, age 75, right hemisphere 16.2
Inferior frontal gyrus, opercular
nTPM: 25.7
2865 Male, age 61, left hemisphere 34.6
2866 Male, age 61, right hemisphere 33.1
2872 Female, age 94, right hemisphere 31.1
2869 Male, age 74, left hemisphere 26.4
2873 Female, age 85, left hemisphere 25.6
2871 Female, age 94, left hemisphere 24.9
2875 Female, age 67, left hemisphere 22.9
2868 Male, age 75, right hemisphere 21.4
2867 Male, age 75, left hemisphere 19.6
2874 Female, age 85, right hemisphere 17.5
Inferior parietal lobule
nTPM: 28.2
2876 Male, age 76, right hemisphere 38.4
2418 Male, age 75, left hemisphere 27.2
2606 Female, age 67, right hemisphere 24.5
2599 Female, age 94, left hemisphere 22.7
Inferior temporal gyrus
nTPM: 30.7
1965 Female, age 91, left hemisphere 38.0
1880 Male, age 80, right hemisphere 36.6
1808 Male, age 76, left hemisphere 32.5
1970 Female, age 85, right hemisphere 29.9
2689 Female, age 94, right hemisphere 23.8
2430 Male, age 75, right hemisphere 23.5
Intraparietal deep sulcus
nTPM: 21.1
2230 Male, age 61, right hemisphere 31.1
2798 Male, age 76, left hemisphere 27.0
2600 Female, age 94, right hemisphere 19.1
2607 Female, age 67, right hemisphere 17.5
2669 Male, age 75, left hemisphere 16.5
2102 Female, age 91, left hemisphere 15.2
Lingual gyrus
nTPM: 32.5
1893 Male, age 76, left hemisphere 42.2
2838 Male, age 80, right hemisphere 42.2
2618 Female, age 94, left hemisphere 31.1
2073 Female, age 85, left hemisphere 27.2
2688 Male, age 75, right hemisphere 19.8
Middle cingulate cortex
nTPM: 25.4
2028 Female, age 85, left hemisphere 32.0
2357 Female, age 67, right hemisphere 29.8
2539 Male, age 75, left hemisphere 27.0
2640 Female, age 94, right hemisphere 19.4
2633 Male, age 74, left hemisphere 18.8
Middle temporal gyrus
nTPM: 28.0
2034 Female, age 91, right hemisphere 33.5
1819 Male, age 80, right hemisphere 31.6
1799 Male, age 76, left hemisphere 30.9
2616 Female, age 94, left hemisphere 26.5
2611 Male, age 75, right hemisphere 17.4
Occipital cortex
nTPM: 22.2
1842 Male, age 76, right hemisphere 30.9
2608 Female, age 67, both hemispheres 26.3
2470 Male, age 75, right hemisphere 20.0
2426 Male, age 75, midline 17.4
2677 Female, age 67, right hemisphere 16.6
Olfactory area
nTPM: 47.5
2222 Female, age 67, right hemisphere 62.7
2756 Female, age 67, right hemisphere 62.7
1805 Female, age 85, right hemisphere 49.5
2352 Female, age 94, right hemisphere 47.5
2440 Male, age 75, left hemisphere 31.8
2542 Male, age 74, left hemisphere 30.9
Olfactory tubercle
nTPM: 37.9
1998 Female, age 91, both hemispheres 46.0
1846 Male, age 80, right hemisphere 42.8
2487 Female, age 94, left hemisphere 36.8
2856 Male, age 75, right hemisphere 26.0
Orbitofrontal gyrus, anterior
nTPM: 21.4
2863 Female, age 85, right hemisphere 26.1
2862 Female, age 85, left hemisphere 24.6
2864 Female, age 67, left hemisphere 13.5
Paracentral lobule, anterior
nTPM: 26.7
1926 Male, age 61, left hemisphere 38.2
2340 Female, age 67, right hemisphere 27.2
2474 Male, age 74, left hemisphere 26.7
2638 Female, age 94, right hemisphere 24.4
1754 Male, age 75, left hemisphere 22.6
1776 Female, age 85, right hemisphere 21.4
Paracentral lobule, posterior
nTPM: 26.3
2345 Male, age 61, left hemisphere 42.7
2446 Male, age 75, left hemisphere 27.1
2551 Female, age 94, right hemisphere 26.2
1775 Female, age 85, right hemisphere 18.6
1764 Male, age 74, right hemisphere 16.7
Parietal operculum
nTPM: 23.5
2552 Female, age 94, right hemisphere 29.6
2356 Female, age 67, right hemisphere 25.9
1763 Male, age 74, left hemisphere 23.3
2719 Male, age 75, left hemisphere 15.0
Parieto-insular cortex
nTPM: 28.6
2232 Male, age 61, right hemisphere 37.4
1976 Female, age 91, right hemisphere 33.7
2508 Female, age 94, right hemisphere 26.5
2671 Male, age 75, left hemisphere 23.4
2831 Male, age 76, right hemisphere 22.1
Parieto-occipital transitional area
nTPM: 23.8
2270 Male, age 61, right hemisphere 37.1
1784 Male, age 76, right hemisphere 27.9
2468 Male, age 75, left hemisphere 20.7
2674 Female, age 94, right hemisphere 17.5
2683 Female, age 67, left hemisphere 15.6
Piriform cortex
nTPM: 12.0
2153 Female, age 85, left hemisphere 15.0
2347 Male, age 75, right hemisphere 8.9
Postcentral gyrus
nTPM: 25.6
2533 Male, age 75, right hemisphere 25.6
Postcentral gyrus, dorsal
nTPM: 25.5
2151 Male, age 61, left hemisphere 32.5
2544 Male, age 74, left hemisphere 27.1
2477 Female, age 94, right hemisphere 25.3
2350 Male, age 75, left hemisphere 24.3
1836 Female, age 85, right hemisphere 22.0
2339 Female, age 67, right hemisphere 21.9
Postcentral gyrus, middle
nTPM: 23.6
2248 Male, age 61, left hemisphere 29.1
2444 Male, age 75, left hemisphere 26.2
1897 Female, age 85, right hemisphere 21.4
2146 Female, age 67, right hemisphere 21.1
2545 Male, age 74, left hemisphere 20.1
Postcentral gyrus, ventral
nTPM: 22.4
2836 Female, age 94, right hemisphere 25.3
2024 Female, age 85, right hemisphere 21.8
2445 Male, age 75, left hemisphere 20.1
Posterior cingulate cortex
nTPM: 19.8
2553 Female, age 94, right hemisphere 23.9
2473 Male, age 75, left hemisphere 20.8
1759 Male, age 74, right hemisphere 14.7
Posterior cingulate cortex, dorsal
nTPM: 24.3
2540 Male, age 75, right hemisphere 35.6
2343 Male, age 61, left hemisphere 34.4
2641 Female, age 94, right hemisphere 23.3
2076 Female, age 85, right hemisphere 20.8
2556 Female, age 67, right hemisphere 16.3
2634 Male, age 74, left hemisphere 15.7
Posterior cingulate cortex, ventral
nTPM: 24.6
2346 Male, age 61, left hemisphere 35.0
1994 Female, age 85, right hemisphere 25.6
2541 Male, age 75, right hemisphere 25.0
1762 Female, age 94, right hemisphere 22.9
2448 Female, age 67, right hemisphere 20.4
2635 Male, age 74, left hemisphere 18.9
Posterior insular cortex
nTPM: 33.6
2603 Female, age 94, left hemisphere 43.6
2231 Male, age 61, left hemisphere 37.4
2832 Female, age 91, right hemisphere 31.7
2597 Male, age 75, left hemisphere 30.9
2511 Female, age 67, right hemisphere 30.5
1823 Male, age 76, right hemisphere 27.5
Precentral gyrus
nTPM: 25.6
2557 Male, age 75, right hemisphere 25.6
Precentral gyrus, dorsal
nTPM: 24.2
2476 Female, age 94, right hemisphere 27.3
2442 Male, age 75, left hemisphere 26.7
2354 Female, age 67, right hemisphere 24.7
1756 Male, age 74, left hemisphere 17.9
Precentral gyrus, middle
nTPM: 27.4
1969 Female, age 67, right hemisphere 35.8
1909 Male, age 61, left hemisphere 34.4
2549 Female, age 94, right hemisphere 23.6
2443 Male, age 75, left hemisphere 22.6
2475 Male, age 74, right hemisphere 20.7
Precentral gyrus, ventral
nTPM: 21.9
2550 Female, age 94, right hemisphere 26.8
2678 Male, age 74, left hemisphere 21.6
2662 Female, age 67, right hemisphere 20.9
2630 Male, age 75, left hemisphere 18.4
Precuneus
nTPM: 22.5
2594 Male, age 61, left hemisphere 29.8
1782 Male, age 76, right hemisphere 29.2
2510 Female, age 67, right hemisphere 25.6
2673 Female, age 94, right hemisphere 18.9
1780 Female, age 91, right hemisphere 17.9
2467 Male, age 75, right hemisphere 14.0
Premotor cortex, dorsal
nTPM: 23.2
2027 Male, age 61, left hemisphere 29.9
2554 Female, age 67, right hemisphere 25.2
1878 Female, age 85, right hemisphere 21.5
2536 Male, age 75, left hemisphere 20.1
2631 Male, age 74, left hemisphere 19.3
Premotor cortex, ventral
nTPM: 23.5
1779 Male, age 61, left hemisphere 34.2
2637 Female, age 94, right hemisphere 25.6
1777 Female, age 67, left hemisphere 24.9
2349 Male, age 75, left hemisphere 19.8
1881 Female, age 85, right hemisphere 19.5
1757 Male, age 74, left hemisphere 16.8
Retrosplenial cortex
nTPM: 45.6
1951 Male, age 61, right hemisphere 88.7
1914 Male, age 76, right hemisphere 30.0
2675 Female, age 94, left hemisphere 18.2
Subcentral gyrus, S2
nTPM: 30.1
2072 Male, age 61, left hemisphere 43.9
2555 Female, age 67, right hemisphere 34.0
1964 Female, age 85, right hemisphere 28.9
2839 Female, age 94, right hemisphere 27.1
2762 Male, age 74, left hemisphere 24.5
2351 Male, age 75, left hemisphere 21.9
Superior parietal lobule
nTPM: 24.1
2229 Male, age 61, right hemisphere 28.1
2605 Female, age 67, right hemisphere 24.8
2672 Female, age 94, right hemisphere 24.8
1800 Male, age 76, right hemisphere 24.1
1992 Female, age 91, right hemisphere 18.4
Superior temporal gyrus
nTPM: 28.2
2025 Male, age 80, right hemisphere 32.8
1844 Female, age 91, left hemisphere 32.6
2615 Female, age 94, left hemisphere 31.7
1843 Male, age 76, left hemisphere 26.4
2687 Male, age 75, right hemisphere 17.7
Supplementary motor cortex
nTPM: 25.4
1993 Male, age 61, left hemisphere 34.1
2548 Female, age 94, right hemisphere 27.1
2537 Male, age 75, left hemisphere 23.4
2632 Male, age 74, left hemisphere 16.9
Supramarginal gyrus
nTPM: 27.9
1991 Female, age 91, right hemisphere 34.7
1798 Male, age 76, right hemisphere 30.3
2415 Male, age 61, left hemisphere 30.1
2601 Female, age 94, left hemisphere 23.5
2513 Female, age 72, left hemisphere 21.1
Temporal pole
nTPM: 34.2
1832 Female, age 91, left hemisphere 50.4
2612 Female, age 94, left hemisphere 36.3
2518 Male, age 75, right hemisphere 32.5
1853 Female, age 85, right hemisphere 28.6
1826 Male, age 76, right hemisphere 23.1
Temporo-insular cortex, parainsular gyrus
nTPM: 27.8
1802 Male, age 76, left hemisphere 38.5
2416 Male, age 61, right hemisphere 35.9
2676 Female, age 94, right hemisphere 30.1
2264 Female, age 91, right hemisphere 24.1
2598 Male, age 75, left hemisphere 21.2
2512 Female, age 67, right hemisphere 17.0
Temporo-occipital transitional zone
nTPM: 52.6
1900 Male, age 76, left hemisphere 97.9
1793 Male, age 80, right hemisphere 39.8
2251 Female, age 85, right hemisphere 20.2
Transversal temporal gyrus, anterior
nTPM: 31.8
1888 Female, age 91, left hemisphere 40.7
1809 Male, age 76, right hemisphere 33.9
1910 Male, age 80, right hemisphere 32.4
2522 Female, age 94, left hemisphere 31.4
2610 Male, age 75, right hemisphere 20.7
Transversal temporal gyrus, posterior
nTPM: 28.3
2614 Female, age 94, left hemisphere 37.1
1967 Female, age 91, right hemisphere 32.5
1922 Male, age 76, left hemisphere 27.2
2833 Male, age 80, right hemisphere 25.5
2520 Male, age 75, right hemisphere 19.0

CEREBRAL CORTEX - HPA PFC Brain RNA-seq
Max nTPM 15.5
Sample id Sample description nTPM
Anterior cingulate gyrus, pregenual-dorsal
nTPM: 12.6
1516 Female, age 85, left hemisphere 20.7
1511 Male, age 61, right hemisphere 17.9
1510 Male, age 61, left hemisphere 16.8
1514 Male, age 74, right hemisphere 11.9
1517 Female, age 67, left hemisphere 11.0
1513 Male, age 74, left hemisphere 10.8
1518 Female, age 67, right hemisphere 9.5
1515 Female, age 94, right hemisphere 8.7
1512 Male, age 75, left hemisphere 6.4
Anterior cingulate gyrus, pregenual-ventral
nTPM: 15.5
1519 Male, age 61, left hemisphere 22.2
1523 Female, age 67, left hemisphere 17.5
1521 Male, age 74, left hemisphere 14.8
1522 Male, age 74, right hemisphere 12.9
1520 Male, age 75, right hemisphere 9.8
Anterior cingulate gyrus, subgenual
nTPM: 14.9
1529 Female, age 85, left hemisphere 19.9
1527 Male, age 74, left hemisphere 18.5
1524 Male, age 61, left hemisphere 17.0
1528 Male, age 74, right hemisphere 16.9
1525 Male, age 75, left hemisphere 13.2
1530 Female, age 67, right hemisphere 9.9
1526 Male, age 75, right hemisphere 9.1
Dorsolateral prefrontal cortex
nTPM: 11.6
1450 Female, age 67, right hemisphere 15.1
1446 Male, age 74, right hemisphere 13.1
1447 Female, age 94, left hemisphere 12.9
1448 Female, age 94, right hemisphere 12.3
1449 Female, age 85, right hemisphere 10.3
1444 Male, age 75, left hemisphere 9.8
1445 Male, age 75, right hemisphere 7.9
Dorsomedial prefrontal cortex
nTPM: 10.9
1442 Male, age 75, right hemisphere 14.2
1439 Male, age 61, left hemisphere 13.3
1440 Male, age 61, right hemisphere 9.8
1441 Male, age 75, left hemisphere 9.8
1443 Female, age 67, right hemisphere 7.1
Frontal cortex
nTPM: 9.3
1573 Male, age 61, right hemisphere 13.5
1577 Male, age 74, right hemisphere 13.5
1581 Female, age 85, right hemisphere 11.5
1580 Female, age 85, left hemisphere 10.9
1579 Female, age 94, right hemisphere 9.0
1583 Female, age 67, right hemisphere 8.4
1576 Male, age 74, left hemisphere 8.2
1582 Female, age 67, left hemisphere 8.1
1575 Male, age 75, right hemisphere 7.9
1578 Female, age 94, left hemisphere 7.4
1572 Male, age 61, left hemisphere 7.3
1574 Male, age 75, left hemisphere 6.4
Frontomarginal cortex
nTPM: 11.1
1466 Male, age 61, right hemisphere 15.1
1471 Female, age 85, left hemisphere 12.8
1469 Female, age 94, left hemisphere 11.9
1470 Female, age 94, right hemisphere 11.4
1468 Male, age 74, left hemisphere 11.0
1467 Male, age 75, right hemisphere 10.2
1473 Female, age 67, right hemisphere 10.2
1465 Male, age 61, left hemisphere 9.4
1472 Female, age 67, left hemisphere 7.5
Frontopolar cortex
nTPM: 9.0
1461 Male, age 75, right hemisphere 15.6
1459 Male, age 61, right hemisphere 10.7
1462 Female, age 94, left hemisphere 9.7
1458 Male, age 61, left hemisphere 7.7
1463 Female, age 67, left hemisphere 7.5
1460 Male, age 75, left hemisphere 7.4
1464 Female, age 67, right hemisphere 4.1
Gyrus rectus
nTPM: 9.7
1474 Male, age 61, left hemisphere 14.3
1480 Female, age 85, left hemisphere 13.7
1478 Female, age 94, left hemisphere 12.6
1475 Male, age 61, right hemisphere 10.8
1479 Female, age 94, right hemisphere 8.8
1477 Male, age 75, right hemisphere 5.9
1481 Female, age 67, left hemisphere 5.9
1476 Male, age 75, left hemisphere 5.4
Inferior frontal gyrus, orbital
nTPM: 11.3
1506 Female, age 94, left hemisphere 16.6
1508 Female, age 85, right hemisphere 15.2
1500 Male, age 61, left hemisphere 13.7
1507 Female, age 85, left hemisphere 13.4
1504 Male, age 74, left hemisphere 12.4
1501 Male, age 61, right hemisphere 11.7
1502 Male, age 75, left hemisphere 9.0
1503 Male, age 75, right hemisphere 7.6
1505 Male, age 74, right hemisphere 6.7
1509 Female, age 67, right hemisphere 6.4
Inferior frontal gyrus, triangular
nTPM: 13.7
1543 Male, age 61, right hemisphere 23.3
1545 Male, age 74, right hemisphere 20.8
1546 Female, age 94, right hemisphere 14.1
1542 Male, age 61, left hemisphere 12.6
1549 Female, age 67, left hemisphere 11.8
1547 Female, age 85, left hemisphere 11.6
1548 Female, age 85, right hemisphere 10.5
1544 Male, age 75, right hemisphere 4.7
Orbitofrontal gyrus, lateral
nTPM: 12.0
1498 Female, age 85, right hemisphere 16.0
1493 Male, age 61, right hemisphere 12.9
1497 Female, age 85, left hemisphere 12.7
1495 Female, age 94, left hemisphere 12.3
1496 Female, age 94, right hemisphere 12.2
1494 Male, age 75, left hemisphere 9.2
1499 Female, age 67, right hemisphere 8.9
Orbitofrontal gyrus, medial
nTPM: 7.8
1489 Female, age 85, left hemisphere 12.5
1482 Male, age 61, left hemisphere 10.1
1490 Female, age 85, right hemisphere 10.0
1488 Female, age 94, right hemisphere 9.2
1487 Female, age 94, left hemisphere 8.2
1491 Female, age 67, left hemisphere 7.4
1485 Male, age 74, left hemisphere 7.1
1486 Male, age 74, right hemisphere 7.1
1492 Female, age 67, right hemisphere 7.1
1483 Male, age 75, left hemisphere 4.5
1484 Male, age 75, right hemisphere 2.9
Orbitofrontal gyrus, posterior
nTPM: 11.9
1536 Female, age 94, left hemisphere 20.1
1537 Female, age 94, right hemisphere 17.9
1538 Female, age 85, left hemisphere 16.0
1533 Male, age 75, left hemisphere 12.6
1539 Female, age 85, right hemisphere 12.6
1532 Male, age 61, right hemisphere 12.2
1531 Male, age 61, left hemisphere 10.4
1535 Male, age 74, left hemisphere 10.2
1541 Female, age 67, right hemisphere 7.5
1540 Female, age 67, left hemisphere 7.4
1534 Male, age 75, right hemisphere 4.5
Subcallosal gyrus
nTPM: 12.0
1551 Male, age 61, right hemisphere 19.5
1554 Male, age 74, left hemisphere 16.3
1550 Male, age 61, left hemisphere 15.8
1555 Male, age 74, right hemisphere 15.6
1558 Female, age 85, left hemisphere 14.0
1557 Female, age 94, right hemisphere 12.7
1559 Female, age 85, right hemisphere 10.9
1561 Female, age 67, right hemisphere 10.4
1556 Female, age 94, left hemisphere 7.9
1552 Male, age 75, left hemisphere 7.3
1553 Male, age 75, right hemisphere 7.1
1560 Female, age 67, left hemisphere 6.8
Superior frontal gyrus
nTPM: 9.8
1562 Male, age 61, left hemisphere 12.4
1569 Female, age 85, left hemisphere 12.2
1570 Female, age 85, right hemisphere 11.6
1563 Male, age 61, right hemisphere 10.8
1567 Female, age 94, left hemisphere 10.4
1568 Female, age 94, right hemisphere 8.9
1564 Male, age 75, left hemisphere 8.5
1565 Male, age 75, right hemisphere 8.3
1566 Male, age 74, right hemisphere 8.3
1571 Female, age 67, right hemisphere 6.3
Temporal cortex
nTPM: 11.3
1595 Female, age 94, right hemisphere 15.0
1592 Male, age 74, left hemisphere 14.1
1593 Male, age 74, right hemisphere 13.7
1594 Female, age 94, left hemisphere 12.5
1590 Male, age 61, right hemisphere 9.8
1596 Female, age 85, right hemisphere 9.8
1591 Male, age 75, right hemisphere 4.1
Ventrolateral prefrontal cortex
nTPM: 10.7
1452 Male, age 74, left hemisphere 14.1
1454 Female, age 94, left hemisphere 12.9
1455 Female, age 85, right hemisphere 12.3
1453 Male, age 74, right hemisphere 11.7
1457 Female, age 67, right hemisphere 11.5
1451 Male, age 75, right hemisphere 8.0
1456 Female, age 67, left hemisphere 4.2
Ventromedial prefrontal cortex
nTPM: 13.6
1436 Female, age 85, left hemisphere 27.2
1432 Male, age 61, left hemisphere 16.5
1437 Female, age 85, right hemisphere 14.9
1433 Male, age 61, right hemisphere 12.3
1435 Female, age 94, right hemisphere 10.4
1438 Female, age 67, left hemisphere 7.6
1434 Male, age 75, right hemisphere 6.4

CEREBRAL CORTEX - GTEx RNA-seqi
Average nTPM 29.4
GTEx sample id Sample description nTPM
Brain - Anterior cingulate cortex (BA24)
Average nTPM: 29.4
Samples: 176

Max nTPM: 68.9
Min nTPM: 1.9
Std nTPM: 12.1
Median nTPM: 28.7
GTEX-1F7RK-0011-R3b-SM-9OSWJ 20-29 years, female 68.9
GTEX-14JG1-0011-R3a-SM-62LEC 40-49 years, male 63.5
GTEX-131YS-0011-R3b-SM-5DUXB 60-69 years, female 63.4
GTEX-11DXW-0011-R3b-SM-DNZZE 40-49 years, male 61.8
GTEX-1KD4Q-0011-R3b-SM-EXOID 40-49 years, male 56.6
GTEX-1HUB1-0011-R3b-SM-CKZOX 60-69 years, male 56.5
GTEX-1C6WA-0011-R3a-SM-9OSVP 60-69 years, male 53.8
GTEX-1MCQQ-0011-R3a-SM-EXURW 60-69 years, male 50.5
GTEX-ZE9C-0011-R3a-SM-4WKGT 60-69 years, male 50.2
GTEX-14BMV-0011-R3a-SM-5ZZU7 50-59 years, male 47.5
GTEX-1F6I4-0011-R3a-SM-9QEH9 60-69 years, male 47.0
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Brain - Cortex
Average nTPM: 27.0
Samples: 255

Max nTPM: 57.4
Min nTPM: 2.0
Std nTPM: 10.0
Median nTPM: 25.8
GTEX-1M4P7-2726-SM-E9TJQ 60-69 years, male 57.4
GTEX-WHSE-3026-SM-3P5ZH 20-29 years, male 56.7
GTEX-1PPGY-3126-SM-EXUSR 60-69 years, male 52.8
GTEX-13SLX-3126-SM-5S2Q5 50-59 years, female 52.7
GTEX-T5JC-2426-SM-3NMDB 20-29 years, male 51.3
GTEX-1HCU6-3126-SM-CL54L 60-69 years, female 50.9
GTEX-1GN73-3126-SM-9KNTY 60-69 years, male 49.0
GTEX-13QIC-2926-SM-5J2NF 60-69 years, female 48.9
GTEX-1HT8W-3026-SM-CGQEO 30-39 years, male 48.6
GTEX-1EWIQ-3126-SM-7MXTI 70-79 years, female 48.4
GTEX-13NYB-3026-SM-5IJD7 40-49 years, male 47.9
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Brain - Frontal Cortex (BA9)
Average nTPM: 25.8
Samples: 209

Max nTPM: 65.8
Min nTPM: 3.5
Std nTPM: 11.3
Median nTPM: 24.9
GTEX-1GF9V-0011-R10b-SM-CKZNP 60-69 years, male 65.8
GTEX-X261-0011-R10B-SM-4E3JT 50-59 years, male 64.4
GTEX-1GMRU-0011-R10b-SM-CJI2L 50-59 years, male 58.1
GTEX-13O3O-0011-R10a-SM-5LUA9 60-69 years, female 57.7
GTEX-13OW7-0011-R10a-SM-5L3H3 50-59 years, male 55.8
GTEX-13SLX-0011-R10a-SM-5P9HV 50-59 years, female 55.5
GTEX-16GPK-0011-R10b-SM-7MKFG 60-69 years, male 47.1
GTEX-1F7RK-0011-R10b-SM-ARU7Y 20-29 years, female 46.0
GTEX-1H4P4-0011-R10b-SM-CE6SG 50-59 years, male 44.9
GTEX-12ZZX-0011-R10b-SM-5DUWK 40-49 years, female 44.7
GTEX-1HBPI-0011-R10a-SM-A96RZ 50-59 years, male 43.4
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CEREBRAL CORTEX - FANTOM5 CAGEi
Max Scaled Tags Per Million 47.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Occipital cortex
Scaled Tags Per Million: 11.1
FF:10163-103B1 76 years, female 11.1
Postcentral gyrus
Scaled Tags Per Million: 35.1
FF:10032-101E5 44-52 years, mixed 35.1
Frontal lobe
Scaled Tags Per Million: 25.6
FF:10040-101F4 32-61 years, mixed 25.6
Insula
Scaled Tags Per Million: 35.5
FF:10039-101F3 20-68 years, mixed 35.5
Medial frontal gyrus
Scaled Tags Per Million: 19.5
FF:10150-102I6 76 years, female 19.5
Medial temporal gyrus
Scaled Tags Per Million: 18.4
FF:10183-103D3 60 years, female 20.1
FF:10156-103A3 76 years, female 16.6
Occipital lobe
Scaled Tags Per Million: 28.1
FF:10076-102A4 27 years, male 28.1
Occipital pole
Scaled Tags Per Million: 31.5
FF:10036-101E9 22-68 years, mixed 31.5
Paracentral gyrus
Scaled Tags Per Million: 31.2
FF:10035-101E8 22-69 years, mixed 31.2
Parietal lobe
Scaled Tags Per Million: 20.1
FF:10034-101E7 35-89 years, mixed 23.7
FF:10171-103B9 60 years, female 18.5
FF:10157-103A4 76 years, female 18.0
Temporal lobe
Scaled Tags Per Million: 47.7
FF:10031-101E4 32-61 years, mixed 47.7

CEREBRAL CORTEX - Pig RNA-seqi
Average nTPM 51.8
Pig sample Sample description nTPM
Occipital cortex
nTPM: 37.9
Samples: 4

Max nTPM: 41.8
Min nTPM: 34.4
Sample A Female 39.8
Sample B Female 34.4
Sample C Male 41.8
Sample D Male 35.5
Retrosplenial cortex
nTPM: 40.0
Samples: 4

Max nTPM: 51.1
Min nTPM: 30.7
Sample A Female 51.1
Sample B Female 33.9
Sample C Male 44.3
Sample D Male 30.7
Cingulate cortex
nTPM: 40.8
Samples: 4

Max nTPM: 53.5
Min nTPM: 33.9
Sample A Female 40.0
Sample B Female 33.9
Sample C Male 53.5
Sample D Male 35.9
Insular cortex
nTPM: 34.6
Samples: 4

Max nTPM: 44.8
Min nTPM: 26.1
Sample A Female 44.8
Sample B Female 26.1
Sample C Male 36.6
Sample D Male 30.7
Motor cortex
nTPM: 44.7
Samples: 4

Max nTPM: 51.6
Min nTPM: 35.6
Sample A Female 46.0
Sample B Female 45.7
Sample C Male 51.6
Sample D Male 35.6
Prefrontal cortex
nTPM: 51.8
Samples: 4

Max nTPM: 57.7
Min nTPM: 45.7
Sample A Female 54.6
Sample B Female 57.7
Sample C Male 49.1
Sample D Male 45.7
Somatosensory cortex
nTPM: 39.2
Samples: 3

Max nTPM: 43.5
Min nTPM: 34.1
Sample B Female 40.1
Sample C Male 43.5
Sample D Male 34.1
Temporal cortex
nTPM: 37.8
Samples: 4

Max nTPM: 43.0
Min nTPM: 32.0
Sample A Female 43.0
Sample B Female 41.2
Sample C Male 35.0
Sample D Male 32.0

CEREBRAL CORTEX - Mouse RNA-seqi
Average nTPM 36.0
Mouse sample Sample description nTPM
Occipital cortex
nTPM: 27.7
Samples: 4

Max nTPM: 37.3
Min nTPM: 18.5
Sample A Male 28.8
Sample B Male 18.5
Sample C Female 26.3
Sample D Female 37.3
Frontal cortex
nTPM: 33.2
Samples: 4

Max nTPM: 41.3
Min nTPM: 21.0
Sample A Male 21.0
Sample B Male 41.3
Sample C Female 39.7
Sample D Female 30.7
Retrosplenial and cingulate cortex
nTPM: 30.1
Samples: 4

Max nTPM: 35.2
Min nTPM: 25.6
Sample A Male 33.4
Sample B Male 35.2
Sample C Female 25.6
Sample D Female 26.2
Somatosensory cortex
nTPM: 36.0
Samples: 4

Max nTPM: 41.6
Min nTPM: 27.4
Sample A Male 27.4
Sample B Male 37.0
Sample C Female 41.6
Sample D Female 38.1

CEREBRAL CORTEX - Allen Mouse ISHi
Max Expression energy 0.5
Allen experiment id Experiment description Expression energy
Cerebral cortex
Expression energy: 0.5
71492952 Antisense, RP_050913_01_H03, Mouse strain C57BL/6J (56 days, male) 0.5
73636038 Antisense, RP_050913_01_H03, Mouse strain C57BL/6J (56 days, male) 0.2

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