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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
No data
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
7.5
nTPM
HPA Brain:
22.2
nTPM
GTEx:
7.5
nTPM
Pig:
13.7
nTPM
Mouse:
35.8
nTPM
Allen mouse:
0.8
Expression energy
MIDBRAIN - Annotated protein expression
Pending normal tissue analysis
MIDBRAIN - HPA Brain RNA-seq
Max nTPM
22.2
Sample id
Sample description
nTPM
Cuneiform nucleus nTPM: 14.8
2219
Male, age 76, both hemispheres
24.9
1827
Male, age 72, unknown
17.1
2586
Male, age 75, left hemisphere
16.0
2828
Female, age 72, unknown
15.4
2019
Male, age 18, unknown
14.9
2666
Male, age 74, left hemisphere
14.2
2411
Female, age 72, unknown
13.3
1870
Female, age 42, unknown
11.3
1833
Male, age 53, unknown
11.1
1830
Male, age 51, unknown
10.2
Dorsal raphe nucleus nTPM: 14.5
2298
Female, age 72, unknown
16.0
1828
Male, age 53, unknown
15.2
2016
Female, age 72, unknown
14.0
2047
Male, age 72, unknown
13.8
2750
Male, age 76, both hemispheres
13.3
Inferior colliculus nTPM: 15.1
2097
Female, age 72, unknown
19.0
1890
Male, age 53, unknown
17.3
2849
Male, age 72, unknown
12.2
1848
Female, age 42, unknown
12.0
Median raphe nucleus nTPM: 15.6
2220
Male, age 76, midline
15.6
Periaquaductal grey, anterior nTPM: 18.4
1795
Male, age 51, unknown
18.7
1947
Male, age 18, unknown
18.7
2502
Female, age 75, unknown
17.8
Periaquaductal grey, dorsal nTPM: 14.5
1831
Male, age 72, unknown
15.9
1840
Male, age 53, unknown
15.0
2850
Male, age 76, both hemispheres
14.7
2464
Female, age 72, unknown
12.4
Periaquaductal grey, lateral nTPM: 14.0
2140
Male, age 76, both hemispheres
15.4
2272
Male, age 74, both hemispheres
13.8
2053
Male, age 18, unknown
12.9
Pretectal area nTPM: 17.8
1816
Male, age 51, unknown
24.5
2007
Male, age 72, unknown
22.2
1944
Female, age 72, unknown
22.1
1817
Female, age 42, unknown
21.6
1815
Male, age 53, unknown
20.2
2667
Female, age 75, unknown
17.5
2224
Female, age 72, unknown
15.0
2273
Male, age 74, both hemispheres
14.6
2316
Male, age 76, right hemisphere
13.4
2407
Male, age 75, both hemispheres
12.7
2825
Male, age 18, unknown
12.0
Red nucleus nTPM: 12.1
2785
Male, age 18, unknown
16.3
1821
Female, age 72, unknown
13.9
2725
Female, age 75, unknown
13.6
2588
Male, age 74, left hemisphere
13.0
2584
Male, age 75, left hemisphere
12.5
2503
Female, age 72, unknown
11.6
1954
Female, age 42, unknown
11.3
1904
Male, age 53, unknown
10.9
2823
Male, age 76, right hemisphere
10.9
1865
Male, age 51, unknown
10.6
2769
Male, age 72, unknown
10.3
2227
Male, age 72, unknown
9.8
Substantia nigra nTPM: 22.2
1916
Female, age 42, unknown
34.5
2241
Male, age 72, unknown
27.2
1851
Male, age 51, unknown
26.1
1941
Male, age 53, unknown
23.8
2409
Female, age 72, unknown
21.4
2665
Male, age 74, both hemispheres
20.7
1889
Female, age 72, unknown
20.0
2699
Male, age 18, unknown
19.0
2590
Female, age 75, unknown
15.3
2583
Male, age 75, right hemisphere
14.4
Superior colliculus nTPM: 14.8
2668
Female, age 75, unknown
18.5
2261
Male, age 18, unknown
18.1
2087
Female, age 72, unknown
17.4
1796
Male, age 53, unknown
16.1
2664
Male, age 75, both hemispheres
14.4
2587
Male, age 74, left hemisphere
13.8
1895
Male, age 76, right hemisphere
13.4
1913
Female, age 42, unknown
12.2
1995
Male, age 72, unknown
12.2
1839
Male, age 51, unknown
11.6
Ventral tegmental area nTPM: 18.5
2218
Male, age 76, both hemispheres
23.0
1915
Female, age 42, unknown
21.8
2410
Female, age 72, unknown
20.8
1942
Male, age 51, unknown
20.0
2021
Male, age 53, unknown
14.0
2223
Female, age 72, unknown
11.4
MIDBRAIN - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Average nTPM
7.5
GTEx sample id
Sample description
nTPM
Brain - Substantia nigra Average nTPM: 7.5
Samples: 139
Max nTPM: 23.9
Min nTPM: 2.2
Std nTPM: 4.3
Median nTPM: 6.1
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Average nTPM
35.8
Mouse sample
Sample description
nTPM
Midbrain nTPM: 35.8
Samples: 4
Max nTPM: 40.1
Min nTPM: 29.3
Sample A
Male
29.3
Sample B
Male
37.7
Sample C
Female
40.1
Sample D
Female
36.0
MIDBRAIN - Allen Mouse ISHi
In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.
The Human Protein Atlas project is funded
