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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Glial cells:
Not detected
Neuronal cells:
Medium
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
9.4
nTPM
HPA Brain:
69.2
nTPM
GTEx:
9.4
nTPM
Pig:
20.6
nTPM
Mouse:
36.6
nTPM
Allen mouse:
10.6
Expression energy
HIPPOCAMPUS - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA039380
Glial cells
Not detected
Neuronal cells
Medium
HIPPOCAMPAL FORMATION - HPA Brain RNA-seq
Max nTPM
69.2
Sample id
Sample description
nTPM
Hippocampus nTPM: 58.3
2621
Female, age 67, right hemisphere
74.4
2148
Female, age 91, left hemisphere
69.1
1855
Male, age 76, left hemisphere
56.3
1911
Female, age 85, right hemisphere
56.1
1898
Male, age 80, left hemisphere
50.0
2529
Female, age 94, left hemisphere
43.7
Dentate gyrus nTPM: 61.3
2531
Female, age 67, both hemispheres
88.8
1927
Female, age 91, both hemispheres
76.7
2246
Female, age 85, both hemispheres
62.3
2528
Male, age 74, both hemispheres
48.4
2530
Female, age 94, left hemisphere
47.0
2010
Male, age 76, both hemispheres
44.7
Entorhinal gyrus nTPM: 67.0
2613
Female, age 94, left hemisphere
81.0
2686
Male, age 75, right hemisphere
75.4
2764
Male, age 80, right hemisphere
74.1
1787
Male, age 76, left hemisphere
64.1
1938
Female, age 85, left hemisphere
61.0
2117
Female, age 91, right hemisphere
46.3
Hippocampus, CA1 nTPM: 59.1
2045
Male, age 76, both hemispheres
79.2
2749
Male, age 80, left hemisphere
66.4
2082
Female, age 91, right hemisphere
52.1
1873
Female, age 85, both hemispheres
49.7
2527
Male, age 74, both hemispheres
48.2
Hippocampus, CA2 nTPM: 53.5
1892
Male, age 76, both hemispheres
67.7
2437
Female, age 94, left hemisphere
58.1
1940
Female, age 85, left hemisphere
56.5
1963
Male, age 80, left hemisphere
48.6
2113
Female, age 91, right hemisphere
48.5
2249
Male, age 74, both hemispheres
41.7
Hippocampus, CA3 nTPM: 68.1
2861
Female, age 67, both hemispheres
87.4
2620
Female, age 94, left hemisphere
87.0
2137
Male, age 80, left hemisphere
80.8
1867
Male, age 76, both hemispheres
56.0
2436
Male, age 74, both hemispheres
49.1
1891
Female, age 85, both hemispheres
48.6
Parahippocampal cortex nTPM: 66.9
2622
Female, age 67, right hemisphere
94.1
2693
Female, age 94, both hemispheres
79.7
2532
Female, age 72, left hemisphere
71.1
2245
Female, age 91, both hemispheres
70.6
1850
Male, age 80, both hemispheres
67.9
1933
Female, age 85, both hemispheres
65.5
2692
Male, age 74, both hemispheres
59.6
2250
Female, age 67, right hemisphere
56.3
1990
Female, age 91, right hemisphere
54.0
2018
Male, age 76, both hemispheres
50.2
Perirhinal gyrus nTPM: 69.2
1847
Female, age 91, left hemisphere
77.2
2848
Male, age 76, right hemisphere
72.9
1794
Male, age 80, right hemisphere
68.1
2521
Female, age 94, right hemisphere
64.0
1841
Female, age 85, right hemisphere
63.8
Subiculum nTPM: 52.0
2729
Female, age 91, right hemisphere
58.8
2619
Male, age 74, both hemispheres
56.2
1901
Male, age 80, both hemispheres
54.6
1977
Female, age 85, both hemispheres
53.2
2438
Female, age 94, left hemisphere
51.0
2042
Male, age 76, both hemispheres
38.3
HIPPOCAMPAL FORMATION - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Average nTPM
9.4
GTEx sample id
Sample description
nTPM
Brain - Hippocampus Average nTPM: 9.4
Samples: 197
Max nTPM: 24.1
Min nTPM: 3.3
Std nTPM: 3.9
Median nTPM: 8.6
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Average nTPM
36.6
Mouse sample
Sample description
nTPM
Entorhinal cortex nTPM: 36.6
Samples: 4
Max nTPM: 37.9
Min nTPM: 36.1
Sample A
Male
36.2
Sample B
Male
37.9
Sample C
Female
36.1
Sample D
Female
36.2
Hippocampal formation nTPM: 31.7
Samples: 4
Max nTPM: 34.4
Min nTPM: 30.4
Sample A
Male
30.4
Sample B
Male
34.4
Sample C
Female
30.4
Sample D
Female
31.7
HIPPOCAMPAL FORMATION - Allen Mouse ISHi
In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.
The Human Protein Atlas project is funded
