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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Low
Hepatocytes:
High
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
109.7
nTPM
HPA:
109.7
nTPM
GTEx:
58.3
nTPM
FANTOM5:
175.4
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA036564
Antibody HPA036565
Antibody CAB033552
Cholangiocytes
Low
Medium
Low
Hepatocytes
High
High
Not detected
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPM
109.7
Female, age 60
Liver sample 21 nTPM: 86.9
Male, age 54
Liver sample 23 nTPM: 77.4
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 88.6
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 167.3
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 131.4
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 103.9
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 122.8
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 85.7
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 103.7
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 129.7
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Average nTPM
58.3
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 58.3
Samples: 226
Max nTPM: 105.1
Min nTPM: 33.9
Std nTPM: 10.0
Median nTPM: 57.5
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
105.1
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
92.6
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
90.0
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
84.9
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
82.2
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
80.5
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
79.4
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
77.7
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
77.4
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
77.4
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
76.6
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
75.7
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
75.0
GTEX-18A7A-1526-SM-72D69
50-59 years, female
74.8
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
74.1
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
73.9
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
73.8
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
73.1
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
71.6
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
71.6
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
71.2
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
70.3
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
69.9
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
69.8
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
69.3
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
69.0
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
68.8
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
68.4
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
68.4
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
68.2
GTEX-R53T-0326-SM-48FEC
50-59 years, female
68.1
GTEX-14JG1-1626-SM-664NH
40-49 years, male
67.9
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
67.9
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
67.7
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
67.6
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
67.1
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
66.6
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
66.2
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
65.9
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
65.2
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
64.9
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
64.8
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
64.8
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
64.7
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
64.5
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
64.5
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
64.4
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
64.3
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
64.2
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
63.8
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
63.6
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
63.6
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
63.4
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
63.4
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
63.4
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
63.4
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
63.4
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
63.4
GTEX-S32W-1926-SM-4AD63
50-59 years, female
63.3
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
63.2
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
62.9
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
62.7
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
62.6
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
62.5
GTEX-11GSP-0626-SM-5986T
60-69 years, female
62.5
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
62.4
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
62.0
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
62.0
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
61.9
GTEX-O5YV-0726-SM-EV798
60-69 years, female
61.9
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
61.8
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
61.7
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
61.7
GTEX-Q734-0326-SM-48U15
40-49 years, female
61.6
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
61.6
GTEX-14E7W-1526-SM-6871X
70-79 years, male
61.5
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
61.3
GTEX-17HHE-0126-SM-79398
50-59 years, male
61.1
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
61.1
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
61.0
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
61.0
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
61.0
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
61.0
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
60.9
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
60.8
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
60.6
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
60.6
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
60.6
GTEX-1399T-0826-SM-5IFES
60-69 years, male
60.4
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
60.4
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
60.3
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
60.3
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
60.1
GTEX-14PHX-0526-SM-664NW
50-59 years, male
59.7
GTEX-YECK-1926-SM-4W21H
60-69 years, male
59.6
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
59.6
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
59.1
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
58.8
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
58.7
GTEX-144GL-1426-SM-79OMA
50-59 years, male
58.7
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
58.6
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
58.5
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
58.4
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
58.4
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
58.4
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
58.3
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
58.2
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
58.2
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
58.2
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
57.7
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
57.7
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
57.7
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
57.5
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
57.5
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
57.4
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
57.4
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
57.3
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
57.1
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
57.1
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
57.0
GTEX-QESD-2026-SM-447BI
20-29 years, male
56.8
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
56.8
GTEX-RU72-1426-SM-46MUF
50-59 years, female
56.7
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
56.6
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
56.6
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
56.5
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
56.5
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
56.4
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
56.4
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
56.2
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
56.1
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
55.7
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
55.7
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
55.6
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
55.6
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
55.5
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
55.5
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
55.5
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
55.3
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
55.3
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
55.3
GTEX-RN64-1826-SM-48FDV
50-59 years, male
55.0
GTEX-17F96-1226-SM-79OK2
70-79 years, male
54.9
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
54.9
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
54.5
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
54.4
GTEX-1B932-1426-SM-793AN
40-49 years, female
54.2
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
54.2
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
54.0
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
53.8
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
53.8
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
53.8
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
53.7
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
53.7
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
53.5
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
53.4
GTEX-14XAO-0226-SM-68728
60-69 years, female
53.3
GTEX-P78B-1326-SM-3P611
40-49 years, female
53.3
GTEX-S33H-1626-SM-4AD68
30-39 years, male
53.3
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
53.2
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
53.2
GTEX-18A66-2026-SM-7189C
60-69 years, male
53.2
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
53.1
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
53.1
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
53.1
GTEX-13112-1426-SM-5EGH8
50-59 years, male
53.0
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
53.0
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
52.7
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
52.6
GTEX-REY6-1226-SM-48FDR
60-69 years, male
52.3
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
52.3
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
52.0
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
51.8
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
51.6
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
51.6
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
51.3
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
51.2
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
51.1
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
51.0
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
51.0
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
50.8
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
50.8
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
50.6
GTEX-12696-0826-SM-5EGGE
60-69 years, male
50.5
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
50.5
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
50.5
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
50.4
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
50.2
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
50.1
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
49.9
GTEX-11ZUS-2526-SM-59872
30-39 years, male
49.8
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
49.4
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
49.1
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
48.8
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
48.7
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
48.7
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
48.6
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
48.5
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
48.3
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
48.2
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
48.0
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
48.0
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
47.5
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
46.3
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
46.3
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
46.3
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
45.6
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
45.4
GTEX-X261-1726-SM-4PQYT
50-59 years, male
44.7
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
44.5
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
44.2
GTEX-13113-1326-SM-5GCOI
60-69 years, female
44.1
GTEX-QEL4-1226-SM-447A4
50-59 years, male
44.1
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
43.8
GTEX-1B933-1226-SM-731DW
50-59 years, female
43.3
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
41.8
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
40.7
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
40.4
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
39.3
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
39.3
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
37.9
GTEX-18465-1626-SM-7LG6N
50-59 years, male
37.7
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
37.6
GTEX-14PJO-1726-SM-68719
60-69 years, male
37.3
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
36.8
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
33.9
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
The Human Protein Atlas project is funded
