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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Medium
Hepatocytes:
Medium
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
30.6
nTPM
HPA:
30.6
nTPM
GTEx:
24.0
nTPM
FANTOM5:
42.0
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA003916
Antibody CAB037318
Cholangiocytes
Low
Medium
Hepatocytes
Low
Medium
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPM
30.6
Female, age 60
Liver sample 21 nTPM: 39.1
Male, age 54
Liver sample 23 nTPM: 29
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 30.5
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 38.2
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 22
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 29.8
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 36
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 26
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 23
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 32.2
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Average nTPM
24.0
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 24.0
Samples: 226
Max nTPM: 59.1
Min nTPM: 3.2
Std nTPM: 10.6
Median nTPM: 22.9
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
59.1
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
52.6
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
49.5
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
45.6
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
45.6
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
45.5
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
43.8
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
43.7
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
43.2
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
43.1
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
42.6
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
42.2
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
42.1
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
41.7
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
41.6
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
40.6
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
40.2
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
39.8
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
39.6
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
38.9
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
38.7
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
38.7
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
38.6
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
37.7
GTEX-14PHX-0526-SM-664NW
50-59 years, male
37.5
GTEX-14XAO-0226-SM-68728
60-69 years, female
37.4
GTEX-13113-1326-SM-5GCOI
60-69 years, female
37.2
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
37.0
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
37.0
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
36.2
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
35.9
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
35.8
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
35.7
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
35.4
GTEX-18A66-2026-SM-7189C
60-69 years, male
35.4
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
35.3
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
35.3
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
35.3
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
35.2
GTEX-O5YV-0726-SM-EV798
60-69 years, female
34.9
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
34.1
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
34.0
GTEX-14JG1-1626-SM-664NH
40-49 years, male
33.5
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
33.5
GTEX-12696-0826-SM-5EGGE
60-69 years, male
33.4
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
33.1
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
32.6
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
32.5
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
32.5
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
32.2
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
32.2
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
32.1
GTEX-Q734-0326-SM-48U15
40-49 years, female
31.9
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
31.6
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
31.3
GTEX-P78B-1326-SM-3P611
40-49 years, female
31.3
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
31.3
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
31.3
GTEX-14PJO-1726-SM-68719
60-69 years, male
31.2
GTEX-17HHE-0126-SM-79398
50-59 years, male
30.8
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
30.7
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
30.5
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
30.4
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
30.0
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
30.0
GTEX-14E7W-1526-SM-6871X
70-79 years, male
29.9
GTEX-1B932-1426-SM-793AN
40-49 years, female
29.8
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
29.5
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
29.5
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
29.3
GTEX-18465-1626-SM-7LG6N
50-59 years, male
29.2
GTEX-QEL4-1226-SM-447A4
50-59 years, male
29.2
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
29.2
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
29.0
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
29.0
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
28.8
GTEX-R53T-0326-SM-48FEC
50-59 years, female
28.8
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
28.6
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
28.5
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
28.2
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
28.0
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
27.9
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
27.4
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
27.3
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
27.2
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
27.0
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
27.0
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
26.8
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
26.7
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
26.6
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
26.3
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
26.1
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
26.1
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
26.0
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
25.8
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
25.8
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
25.7
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
25.7
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
25.7
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
25.0
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
24.8
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
24.7
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
24.5
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
24.5
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
24.4
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
24.1
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
24.0
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
23.9
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
23.8
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
23.6
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
23.2
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
23.0
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
22.9
GTEX-S32W-1926-SM-4AD63
50-59 years, female
22.9
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
22.8
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
22.6
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
22.3
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
22.2
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
22.2
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
22.0
GTEX-18A7A-1526-SM-72D69
50-59 years, female
22.0
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
22.0
GTEX-11GSP-0626-SM-5986T
60-69 years, female
21.8
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
21.8
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
21.6
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
21.6
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
21.6
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
21.6
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
21.5
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
21.5
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
21.2
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
21.2
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
21.2
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
20.9
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
20.8
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
20.7
GTEX-QESD-2026-SM-447BI
20-29 years, male
20.4
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
20.3
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
20.0
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
19.7
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
19.7
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
19.5
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
19.2
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
19.2
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
19.1
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
19.1
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
19.1
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
19.0
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
19.0
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
18.9
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
18.9
GTEX-REY6-1226-SM-48FDR
60-69 years, male
18.5
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
18.3
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
18.3
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
18.3
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
18.2
GTEX-1399T-0826-SM-5IFES
60-69 years, male
17.9
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
17.7
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
17.6
GTEX-11ZUS-2526-SM-59872
30-39 years, male
17.5
GTEX-RN64-1826-SM-48FDV
50-59 years, male
17.5
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
17.3
GTEX-13112-1426-SM-5EGH8
50-59 years, male
17.3
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
17.3
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
17.0
GTEX-S33H-1626-SM-4AD68
30-39 years, male
16.9
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
16.7
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
16.5
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
16.4
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
16.3
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
16.2
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
16.1
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
16.1
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
16.0
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
16.0
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
16.0
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
15.8
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
15.7
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
15.6
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
15.3
GTEX-YECK-1926-SM-4W21H
60-69 years, male
15.2
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
15.1
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
14.8
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
14.7
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
14.5
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
14.4
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
14.3
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
13.2
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
13.2
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
13.2
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
12.9
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
12.9
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
12.5
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
12.4
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
12.1
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
11.9
GTEX-17F96-1226-SM-79OK2
70-79 years, male
11.9
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
11.9
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
11.8
GTEX-X261-1726-SM-4PQYT
50-59 years, male
11.8
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
11.7
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
11.4
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
11.3
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
11.3
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
10.9
GTEX-RU72-1426-SM-46MUF
50-59 years, female
10.7
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
10.4
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
10.0
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
9.9
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
9.1
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
8.0
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
7.6
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
7.5
GTEX-144GL-1426-SM-79OMA
50-59 years, male
6.2
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
6.2
GTEX-1B933-1226-SM-731DW
50-59 years, female
6.0
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
5.1
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
5.1
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
5.0
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
4.9
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
4.7
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
4.7
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
4.1
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
3.7
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
3.5
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
3.2
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
The Human Protein Atlas project is funded
