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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cells in red pulp:
High
Cells in white pulp:
High
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
39.4
nTPM
HPA:
39.4
nTPM
GTEx:
23.1
nTPM
FANTOM5:
57.9
Scaled Tags Per Million
SPLEEN - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA003916
Antibody CAB037318
Cells in red pulp
Low
High
Cells in white pulp
High
High
SPLEEN - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPM
39.4
Female, age 60
Spleen sample 236 nTPM: 35.1
Cell types%
Lymphocytes:
40
Macrophages:
30
Endothelial cells:
15
Fibroblasts:
5
Other cell types:
10
Male, age 17
Spleen sample 237 nTPM: 41.6
Cell types%
Lymphocytes:
40
Macrophages:
35
Endothelial cells:
15
Fibroblasts:
5
Other cell types:
5
Male, age 20
Spleen sample 238 nTPM: 38.5
Cell types%
Lymphocytes:
40
Macrophages:
30
Endothelial cells:
15
Fibroblasts:
5
Other cell types:
10
Female, age 19
Spleen sample 239 nTPM: 40.2
Cell types%
Lymphocytes:
40
Macrophages:
30
Endothelial cells:
15
Fibroblasts:
10
Other cell types:
5
Female, age 65
Spleen sample 378 nTPM: 41.7
Cell types%
Lymphocytes:
35
Macrophages:
30
Endothelial cells:
20
Fibroblasts:
10
Other cell types:
5
SPLEEN - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Average nTPM
23.1
GTEx sample id
Sample description
nTPM
Spleen Average nTPM: 23.1
Samples: 241
Max nTPM: 46.5
Min nTPM: 5.8
Std nTPM: 7.6
Median nTPM: 22.1
GTEX-15RIF-0526-SM-6LLI2
20-29 years, male
46.5
GTEX-15F5U-0126-SM-6LPKA
40-49 years, male
41.9
GTEX-1C475-1126-SM-7MGY7
40-49 years, female
40.8
GTEX-13PVR-0326-SM-5RQJY
60-69 years, female
40.5
GTEX-12BJ1-0726-SM-5EGGF
60-69 years, male
39.9
GTEX-P4PQ-0926-SM-E9U4D
60-69 years, male
39.5
GTEX-1CB4E-0126-SM-7DHMX
60-69 years, male
38.1
GTEX-18A67-1526-SM-7LG6F
50-59 years, male
37.8
GTEX-PLZ6-0126-SM-48TC6
30-39 years, male
37.4
GTEX-13PL7-1126-SM-5MR5O
60-69 years, female
36.7
GTEX-146FR-1926-SM-5NQA6
60-69 years, female
36.7
GTEX-14PKU-0526-SM-6871A
40-49 years, female
36.7
GTEX-ZYFG-0726-SM-5GIDX
60-69 years, female
36.4
GTEX-14E6E-1226-SM-5S2R5
30-39 years, male
36.3
GTEX-Z9EW-0726-SM-5HL9H
40-49 years, male
36.3
GTEX-1MJK3-0126-SM-DPRYY
20-29 years, male
36.3
GTEX-1211K-0426-SM-5FQTP
60-69 years, female
36.2
GTEX-1JKYN-0326-SM-AHZ4D
30-39 years, male
36.1
GTEX-1F5PL-2226-SM-7MKHE
40-49 years, female
35.3
GTEX-11EQ9-0426-SM-5A5JY
30-39 years, male
34.8
GTEX-12WSN-0126-SM-5DUX5
40-49 years, male
34.8
GTEX-147F3-0126-SM-5NQBJ
50-59 years, female
34.7
GTEX-1R9K4-1526-SM-DPRY5
60-69 years, male
34.3
GTEX-T5JW-0126-SM-4DM6K
20-29 years, female
33.8
GTEX-14ICL-0126-SM-664NG
30-39 years, male
33.5
GTEX-13FH7-1326-SM-5IFG8
50-59 years, female
33.4
GTEX-UJHI-0126-SM-4IHLP
50-59 years, female
33.1
GTEX-131XG-0426-SM-5IFGD
50-59 years, female
32.9
GTEX-17GQL-0126-SM-72D5Q
60-69 years, male
32.8
GTEX-1PDJ9-0226-SM-DPRYX
20-29 years, male
32.8
GTEX-14DAR-0326-SM-5S2PS
50-59 years, male
32.7
GTEX-13X6H-0726-SM-5Q5BX
50-59 years, female
32.3
GTEX-111CU-0426-SM-5GZY1
50-59 years, male
32.2
GTEX-XPVG-0626-SM-4B65B
50-59 years, male
32.2
GTEX-OIZF-0926-SM-7MKH7
60-69 years, male
32.1
GTEX-1B8KZ-0226-SM-7EWF6
50-59 years, male
31.7
GTEX-ZEX8-0726-SM-4WKH8
50-59 years, male
31.7
GTEX-132QS-0226-SM-5IFFZ
60-69 years, male
31.6
GTEX-14BMU-0426-SM-73KYT
20-29 years, female
31.3
GTEX-1QAET-2326-SM-EXOJ1
50-59 years, male
31.3
GTEX-14PJ5-0326-SM-664OD
60-69 years, female
31.2
GTEX-14PN3-0226-SM-6871K
60-69 years, female
31.2
GTEX-1122O-0526-SM-5N9DM
60-69 years, female
31.1
GTEX-139T6-0226-SM-5IFGZ
50-59 years, male
31.1
GTEX-1LVAN-1026-SM-CNNQZ
50-59 years, female
31.0
GTEX-12WSK-0126-SM-5GCO7
40-49 years, female
30.1
GTEX-14PK6-0526-SM-69LOF
70-79 years, female
30.1
GTEX-ZLWG-0426-SM-4WWFA
50-59 years, female
29.9
GTEX-16XZY-0126-SM-7IGQ9
70-79 years, male
29.8
GTEX-1KANA-1226-SM-DHXKE
20-29 years, male
29.8
GTEX-1GZ4H-0126-SM-9JGGI
50-59 years, female
29.7
GTEX-117YX-2126-SM-5GIEL
50-59 years, male
29.6
GTEX-YB5E-0426-SM-5IFHR
40-49 years, male
29.6
GTEX-XV7Q-0126-SM-4BRVK
40-49 years, female
29.5
GTEX-1LSNM-0126-SM-EAZ57
50-59 years, male
29.5
GTEX-1HCU9-0126-SM-9WG7M
20-29 years, male
29.3
GTEX-1CB4F-0226-SM-7EPHS
60-69 years, male
29.2
GTEX-XAJ8-0126-SM-47JYG
40-49 years, male
29.1
GTEX-1S831-0726-SM-EV79O
20-29 years, male
29.1
GTEX-ZP4G-0326-SM-4YCEF
20-29 years, female
28.8
GTEX-ZAB5-0526-SM-5CVMU
50-59 years, male
28.7
GTEX-O5YT-0926-SM-48TDG
20-29 years, male
28.6
GTEX-ZZPU-0126-SM-5E446
50-59 years, female
28.6
GTEX-17F98-0126-SM-7MGW3
40-49 years, female
28.4
GTEX-QMRM-0226-SM-CL55S
50-59 years, male
28.3
GTEX-YFCO-0926-SM-5LUA5
40-49 years, male
28.2
GTEX-1B97J-1926-SM-7IGQB
50-59 years, female
27.8
GTEX-12WSJ-0526-SM-5GCOZ
40-49 years, female
27.6
GTEX-144GN-2126-SM-5O99D
50-59 years, male
27.4
GTEX-ZPIC-0126-SM-DNZZ9
40-49 years, female
27.1
GTEX-1399R-0226-SM-5IJGG
30-39 years, male
26.8
GTEX-1R7EU-2026-SM-E9U63
60-69 years, male
26.7
GTEX-WHWD-0126-SM-4OORS
50-59 years, male
26.5
GTEX-14E1K-0126-SM-664NL
50-59 years, male
26.1
GTEX-15RJ7-0126-SM-6LPJN
40-49 years, male
26.0
GTEX-QV44-0126-SM-CJI1X
50-59 years, male
26.0
GTEX-Y3IK-0126-SM-4WWE9
50-59 years, female
25.9
GTEX-1LNCM-0426-SM-DHXK6
50-59 years, female
25.9
GTEX-14PJ4-0526-SM-6871G
60-69 years, male
25.8
GTEX-1RAZQ-0126-SM-EV7B1
30-39 years, male
25.7
GTEX-16MT8-1826-SM-7EWE8
60-69 years, female
25.4
GTEX-P4QT-0926-SM-EZ6KQ
50-59 years, female
25.2
GTEX-18A66-1826-SM-7KFSU
60-69 years, male
25.0
GTEX-15SDE-0126-SM-793BA
50-59 years, female
24.8
GTEX-X3Y1-0126-SM-4PQZA
40-49 years, male
24.8
GTEX-W5WG-0626-SM-4SOID
50-59 years, female
24.7
GTEX-ZDTT-1026-SM-5KM19
60-69 years, male
24.6
GTEX-1AMFI-0926-SM-731E4
50-59 years, female
24.5
GTEX-1FIGZ-0126-SM-7MKGZ
40-49 years, male
24.3
GTEX-1H3VY-1526-SM-9WG7S
50-59 years, male
24.3
GTEX-1KAFJ-1026-SM-D4P2Z
50-59 years, male
24.3
GTEX-13U4I-1626-SM-5IFFR
40-49 years, female
24.2
GTEX-15UF7-1926-SM-6LPJT
40-49 years, male
24.2
GTEX-1JKYR-1126-SM-CGQGJ
20-29 years, male
24.2
GTEX-1F75I-0226-SM-7MKHQ
40-49 years, male
24.1
GTEX-1QCLZ-1026-SM-E6CR1
60-69 years, female
24.0
GTEX-11DXX-0726-SM-5H12X
60-69 years, female
23.9
GTEX-131XE-1126-SM-5EGHW
50-59 years, male
23.9
GTEX-145MN-0126-SM-5RQHY
30-39 years, male
23.8
GTEX-1QCLY-0126-SM-DPRZV
30-39 years, male
23.7
GTEX-ZF29-0626-SM-4WKHD
60-69 years, female
23.6
GTEX-1RMOY-0726-SM-EV79D
50-59 years, male
23.6
GTEX-1MCYP-0226-SM-EV7A3
20-29 years, female
23.5
GTEX-P4PP-0926-SM-48TBZ
30-39 years, female
23.4
GTEX-R55G-0226-SM-48FEI
40-49 years, female
23.3
GTEX-R55C-0126-SM-48FEQ
40-49 years, male
23.3
GTEX-1PPH7-0126-SM-E6CPB
40-49 years, male
23.1
GTEX-1C4CL-0626-SM-731DM
30-39 years, male
23.0
GTEX-1JK1U-0126-SM-C1YQY
60-69 years, male
23.0
GTEX-17F96-1426-SM-7IGQA
70-79 years, male
22.9
GTEX-ZVZP-0726-SM-59HKA
50-59 years, male
22.9
GTEX-QESD-0126-SM-EXOHG
20-29 years, male
22.9
GTEX-POMQ-0126-SM-48TD6
20-29 years, female
22.8
GTEX-11NSD-0426-SM-5N9CR
20-29 years, male
22.7
GTEX-YB5K-1926-SM-4VDT4
40-49 years, female
22.7
GTEX-13111-0126-SM-5EGHO
50-59 years, male
22.6
GTEX-13CF3-0226-SM-5J1NW
60-69 years, female
22.6
GTEX-XMK1-0126-SM-4B65F
40-49 years, male
22.5
GTEX-17HHE-0326-SM-793BH
50-59 years, male
22.3
GTEX-1QP29-0126-SM-EAZ3S
50-59 years, male
22.2
GTEX-14PJ6-0226-SM-6AJ9K
60-69 years, female
22.1
GTEX-15ER7-1526-SM-6LLHO
20-29 years, female
22.1
GTEX-1L5NE-0926-SM-D4P3P
50-59 years, male
22.1
GTEX-1R9K5-1126-SM-EAZ4G
50-59 years, male
22.1
GTEX-1F5PK-0726-SM-7MGXN
50-59 years, male
22.0
GTEX-OOBJ-0926-SM-48TDO
60-69 years, male
21.9
GTEX-1399S-0226-SM-5IFFG
30-39 years, female
21.8
GTEX-S4Z8-0226-SM-4AD5K
60-69 years, male
21.8
GTEX-13S86-0126-SM-5S2PI
40-49 years, male
21.7
GTEX-1AX9K-0226-SM-793CM
50-59 years, male
21.7
GTEX-1MCC2-0826-SM-EV7AM
30-39 years, female
21.6
GTEX-1MUQO-1326-SM-EV7AE
60-69 years, male
21.6
GTEX-1N2EF-1526-SM-EXOIY
60-69 years, male
21.6
GTEX-P78B-1226-SM-EZ6KP
40-49 years, female
21.6
GTEX-11LCK-0126-SM-5A5M5
30-39 years, male
21.5
GTEX-1A3MV-0126-SM-731FQ
30-39 years, male
21.4
GTEX-WYVS-0126-SM-4ONDH
40-49 years, female
21.4
GTEX-ZTTD-1726-SM-57WEL
50-59 years, male
21.4
GTEX-15DZA-0126-SM-6PAMV
30-39 years, female
21.3
GTEX-16MT9-1726-SM-6M47P
60-69 years, female
21.3
GTEX-PX3G-0926-SM-48U12
20-29 years, female
21.3
GTEX-14JG6-0226-SM-6872A
30-39 years, female
21.2
GTEX-1CB4I-1426-SM-79OLZ
50-59 years, male
21.2
GTEX-S3XE-0626-SM-4AD6B
50-59 years, male
21.2
GTEX-XGQ4-0126-SM-4AT4H
50-59 years, male
21.2
GTEX-ZF2S-0326-SM-4WKGD
50-59 years, female
21.2
GTEX-15SHV-0126-SM-6LPIS
60-69 years, male
21.0
GTEX-VJYA-0126-SM-4KL1P
60-69 years, male
20.9
GTEX-WY7C-0126-SM-4ONCO
50-59 years, male
20.9
GTEX-OIZH-0926-SM-48TBR
50-59 years, male
20.7
GTEX-1IDJC-0126-SM-C1YQC
50-59 years, male
20.7
GTEX-139YR-0426-SM-5IFFV
50-59 years, male
20.6
GTEX-RUSQ-0126-SM-47JWV
50-59 years, male
20.6
GTEX-PW2O-0126-SM-48TC8
20-29 years, male
20.5
GTEX-QCQG-0226-SM-48U28
50-59 years, female
20.4
GTEX-1LG7Z-0126-SM-EV79V
30-39 years, male
20.4
GTEX-ZLFU-0526-SM-4WWBN
40-49 years, male
20.3
GTEX-1QP66-0126-SM-EAZ3N
50-59 years, male
20.3
GTEX-1RNTQ-1026-SM-EV7B4
20-29 years, female
20.2
GTEX-1QP2A-2526-SM-EXOJB
50-59 years, male
20.0
GTEX-Y114-0726-SM-4TT6U
50-59 years, female
19.9
GTEX-ZPCL-0626-SM-DNZZ6
60-69 years, female
19.9
GTEX-15ETS-3126-SM-6LPKN
40-49 years, female
19.8
GTEX-1R9PM-0126-SM-DPRY6
20-29 years, male
19.6
GTEX-U3ZH-0126-SM-4DXUK
30-39 years, male
19.1
GTEX-13N11-0126-SM-5KM2Z
50-59 years, female
19.0
GTEX-15RIG-0126-SM-6PAN4
40-49 years, male
18.9
GTEX-1RAZA-1026-SM-E6CQ9
20-29 years, male
18.8
GTEX-11XUK-0426-SM-5EQML
40-49 years, female
18.7
GTEX-ZV6S-0826-SM-5NQ6Z
40-49 years, female
18.7
GTEX-1JMLX-1426-SM-CNNPO
50-59 years, male
18.6
GTEX-1RAZR-1626-SM-EAZ4V
40-49 years, male
18.6
GTEX-1C64O-1626-SM-731EN
60-69 years, male
18.5
GTEX-P4QS-0926-SM-48TBS
60-69 years, male
18.5
GTEX-1LGRB-0126-SM-CNNR6
50-59 years, female
18.5
GTEX-1QW4Y-0126-SM-DPRZQ
30-39 years, male
18.5
GTEX-1HSMQ-0126-SM-D4P2I
50-59 years, male
18.3
GTEX-1IDJE-0126-SM-C1YQ6
50-59 years, female
18.0
GTEX-U3ZN-0126-SM-4DXUM
30-39 years, female
17.9
GTEX-1R7EV-0126-SM-EAZ3O
40-49 years, male
17.7
GTEX-12WSG-0926-SM-5EGIH
50-59 years, female
17.5
GTEX-15SB6-0126-SM-6LPJR
50-59 years, female
17.5
GTEX-QDT8-1526-SM-EXOHP
30-39 years, female
17.5
GTEX-1QMI2-1526-SM-EXOJT
60-69 years, male
17.3
GTEX-X4LF-0226-SM-4QAS8
50-59 years, male
17.2
GTEX-X585-1826-SM-4QAS3
50-59 years, male
17.2
GTEX-Q2AH-0226-SM-48U1I
40-49 years, male
17.1
GTEX-11VI4-0126-SM-5GU6Z
40-49 years, female
17.0
GTEX-169BO-0126-SM-79OLS
50-59 years, male
17.0
GTEX-ZPU1-1026-SM-4YCEQ
40-49 years, male
17.0
GTEX-146FQ-0626-SM-5LU9U
30-39 years, male
16.9
GTEX-1B97I-0126-SM-731DH
40-49 years, male
16.8
GTEX-YEC4-0126-SM-4W21T
40-49 years, male
16.6
GTEX-15CHQ-1226-SM-6ETZL
60-69 years, male
16.3
GTEX-WXYG-0126-SM-4OND7
50-59 years, female
16.3
GTEX-13VXT-1326-SM-5LU3Y
20-29 years, female
16.0
GTEX-11P81-1326-SM-5GU5S
30-39 years, female
15.9
GTEX-1MGNQ-1126-SM-EAZ4Y
40-49 years, male
15.9
GTEX-ZVP2-0526-SM-51MSC
50-59 years, male
15.8
GTEX-1H3O1-1126-SM-9WPO9
60-69 years, male
15.8
GTEX-1OFPY-0126-SM-EXOJ3
60-69 years, male
15.8
GTEX-111FC-1326-SM-5N9D9
60-69 years, male
15.7
GTEX-QV31-0126-SM-447BP
30-39 years, male
15.5
GTEX-11P7K-0426-SM-5BC5H
30-39 years, male
15.3
GTEX-1LSVX-1426-SM-DHXJO
60-69 years, male
15.3
GTEX-ZG7Y-2026-SM-DO91N
50-59 years, male
15.3
GTEX-Y5V5-1126-SM-EVYAR
60-69 years, female
15.2
GTEX-QLQW-0126-SM-447BK
30-39 years, male
15.0
GTEX-Y5LM-0326-SM-4VBRN
40-49 years, female
15.0
GTEX-Y8LW-0126-SM-4VBS1
50-59 years, female
14.2
GTEX-1R9JW-0126-SM-EAZ4P
30-39 years, female
14.2
GTEX-17F9E-1126-SM-79OMO
50-59 years, male
14.1
GTEX-XQ8I-1726-SM-4BOQB
50-59 years, male
14.0
GTEX-XXEK-0126-SM-4BRVU
50-59 years, male
13.9
GTEX-UPK5-1626-SM-4JBHI
40-49 years, male
13.8
GTEX-1J8Q3-0126-SM-C1YSI
60-69 years, male
13.8
GTEX-1JMQK-1126-SM-CXZJW
60-69 years, male
13.7
GTEX-U4B1-0526-SM-4DXTK
40-49 years, male
13.6
GTEX-12WSD-1726-SM-5GCN4
60-69 years, female
13.4
GTEX-1J8QM-0926-SM-C1YQ9
60-69 years, female
13.3
GTEX-13OVK-0426-SM-7KFT8
40-49 years, male
13.0
GTEX-17F97-1626-SM-72D6W
50-59 years, male
12.9
GTEX-Y3I4-0126-SM-4TT26
50-59 years, male
12.7
GTEX-Q734-0226-SM-48U1A
40-49 years, female
12.5
GTEX-1K2DA-0126-SM-CGQGV
50-59 years, male
11.6
GTEX-NFK9-1426-SM-43ISG
40-49 years, male
11.4
GTEX-WFON-0126-SM-4LVM9
40-49 years, male
11.1
GTEX-1JMPZ-0926-SM-CXZJR
30-39 years, male
11.1
GTEX-1C6VQ-2126-SM-7IGNL
50-59 years, male
10.9
GTEX-15DYW-1426-SM-6LPIW
60-69 years, female
10.8
GTEX-1K9T9-0626-SM-CXZKY
50-59 years, female
10.8
GTEX-1PWST-1626-SM-EXOIU
70-79 years, male
10.6
GTEX-ZDYS-1026-SM-4WKHC
50-59 years, male
10.2
GTEX-QDVN-0526-SM-48TZ4
50-59 years, male
10.1
GTEX-1GF9U-0126-SM-AHZ4G
40-49 years, female
9.9
GTEX-15CHC-0726-SM-6AJ9D
60-69 years, female
9.4
GTEX-1PIIG-1226-SM-EXOIQ
30-39 years, male
9.2
GTEX-1AYD5-0226-SM-79ONV
50-59 years, male
8.9
GTEX-1HCU7-1426-SM-CNNQK
50-59 years, male
7.9
GTEX-1KD5A-1526-SM-D4P3W
50-59 years, male
7.9
GTEX-WYJK-0726-SM-4ONC9
50-59 years, male
5.8
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SPLEEN - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
The Human Protein Atlas project is funded
