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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cells in red pulp:
Not detected
Cells in white pulp:
Low
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
32.5
nTPM
HPA:
21.3
nTPM
GTEx:
32.5
nTPM
FANTOM5:
26.1
Scaled Tags Per Million
SPLEEN - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA057888
Cells in red pulp
Not detected
Cells in white pulp
Low
SPLEEN - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPM
21.3
Female, age 60
Spleen sample 236 nTPM: 24.2
Cell types%
Lymphocytes:
40
Macrophages:
30
Endothelial cells:
15
Fibroblasts:
5
Other cell types:
10
Male, age 17
Spleen sample 237 nTPM: 23.1
Cell types%
Lymphocytes:
40
Macrophages:
35
Endothelial cells:
15
Fibroblasts:
5
Other cell types:
5
Male, age 20
Spleen sample 238 nTPM: 20.1
Cell types%
Lymphocytes:
40
Macrophages:
30
Endothelial cells:
15
Fibroblasts:
5
Other cell types:
10
Female, age 19
Spleen sample 239 nTPM: 21.1
Cell types%
Lymphocytes:
40
Macrophages:
30
Endothelial cells:
15
Fibroblasts:
10
Other cell types:
5
Female, age 65
Spleen sample 378 nTPM: 18.1
Cell types%
Lymphocytes:
35
Macrophages:
30
Endothelial cells:
20
Fibroblasts:
10
Other cell types:
5
SPLEEN - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Average nTPM
32.5
GTEx sample id
Sample description
nTPM
Spleen Average nTPM: 32.5
Samples: 241
Max nTPM: 48.6
Min nTPM: 12.0
Std nTPM: 5.9
Median nTPM: 31.9
GTEX-RUSQ-0126-SM-47JWV
50-59 years, male
48.6
GTEX-1JKYR-1126-SM-CGQGJ
20-29 years, male
47.2
GTEX-1LSVX-1426-SM-DHXJO
60-69 years, male
46.4
GTEX-1QW4Y-0126-SM-DPRZQ
30-39 years, male
46.3
GTEX-1LNCM-0426-SM-DHXK6
50-59 years, female
45.5
GTEX-P4QT-0926-SM-EZ6KQ
50-59 years, female
45.4
GTEX-1OFPY-0126-SM-EXOJ3
60-69 years, male
45.1
GTEX-QLQW-0126-SM-447BK
30-39 years, male
45.0
GTEX-P78B-1226-SM-EZ6KP
40-49 years, female
45.0
GTEX-1GF9U-0126-SM-AHZ4G
40-49 years, female
44.9
GTEX-1R9K5-1126-SM-EAZ4G
50-59 years, male
44.7
GTEX-1CB4F-0226-SM-7EPHS
60-69 years, male
43.7
GTEX-QV44-0126-SM-CJI1X
50-59 years, male
43.7
GTEX-PX3G-0926-SM-48U12
20-29 years, female
43.5
GTEX-14PK6-0526-SM-69LOF
70-79 years, female
43.4
GTEX-1F5PL-2226-SM-7MKHE
40-49 years, female
43.3
GTEX-1KANA-1226-SM-DHXKE
20-29 years, male
43.2
GTEX-Y3IK-0126-SM-4WWE9
50-59 years, female
42.0
GTEX-Y5V5-1126-SM-EVYAR
60-69 years, female
41.8
GTEX-16XZY-0126-SM-7IGQ9
70-79 years, male
41.6
GTEX-U3ZH-0126-SM-4DXUK
30-39 years, male
41.3
GTEX-1QAET-2326-SM-EXOJ1
50-59 years, male
41.3
GTEX-1PIIG-1226-SM-EXOIQ
30-39 years, male
40.9
GTEX-18A66-1826-SM-7KFSU
60-69 years, male
40.7
GTEX-XXEK-0126-SM-4BRVU
50-59 years, male
40.6
GTEX-NFK9-1426-SM-43ISG
40-49 years, male
40.6
GTEX-1MUQO-1326-SM-EV7AE
60-69 years, male
40.3
GTEX-1KAFJ-1026-SM-D4P2Z
50-59 years, male
40.1
GTEX-S3XE-0626-SM-4AD6B
50-59 years, male
40.0
GTEX-13OVK-0426-SM-7KFT8
40-49 years, male
39.7
GTEX-1PDJ9-0226-SM-DPRYX
20-29 years, male
39.4
GTEX-146FQ-0626-SM-5LU9U
30-39 years, male
39.1
GTEX-1C64O-1626-SM-731EN
60-69 years, male
39.1
GTEX-U3ZN-0126-SM-4DXUM
30-39 years, female
39.1
GTEX-17F97-1626-SM-72D6W
50-59 years, male
38.8
GTEX-QV31-0126-SM-447BP
30-39 years, male
38.8
GTEX-UPK5-1626-SM-4JBHI
40-49 years, male
38.7
GTEX-XGQ4-0126-SM-4AT4H
50-59 years, male
38.6
GTEX-14E6E-1226-SM-5S2R5
30-39 years, male
38.3
GTEX-16MT8-1826-SM-7EWE8
60-69 years, female
38.3
GTEX-11XUK-0426-SM-5EQML
40-49 years, female
38.0
GTEX-1R7EV-0126-SM-EAZ3O
40-49 years, male
37.9
GTEX-U4B1-0526-SM-4DXTK
40-49 years, male
37.7
GTEX-1QP2A-2526-SM-EXOJB
50-59 years, male
37.7
GTEX-13N11-0126-SM-5KM2Z
50-59 years, female
37.5
GTEX-X4LF-0226-SM-4QAS8
50-59 years, male
37.3
GTEX-13S86-0126-SM-5S2PI
40-49 years, male
37.1
GTEX-POMQ-0126-SM-48TD6
20-29 years, female
37.0
GTEX-QDT8-1526-SM-EXOHP
30-39 years, female
36.9
GTEX-ZVP2-0526-SM-51MSC
50-59 years, male
36.8
GTEX-1H3O1-1126-SM-9WPO9
60-69 years, male
36.7
GTEX-13X6H-0726-SM-5Q5BX
50-59 years, female
36.5
GTEX-Q2AH-0226-SM-48U1I
40-49 years, male
36.4
GTEX-13U4I-1626-SM-5IFFR
40-49 years, female
36.2
GTEX-14PJ6-0226-SM-6AJ9K
60-69 years, female
36.2
GTEX-1JMLX-1426-SM-CNNPO
50-59 years, male
36.2
GTEX-ZPIC-0126-SM-DNZZ9
40-49 years, female
36.2
GTEX-12WSJ-0526-SM-5GCOZ
40-49 years, female
35.9
GTEX-OIZH-0926-SM-48TBR
50-59 years, male
35.9
GTEX-1PPH7-0126-SM-E6CPB
40-49 years, male
35.9
GTEX-YB5K-1926-SM-4VDT4
40-49 years, female
35.8
GTEX-1K9T9-0626-SM-CXZKY
50-59 years, female
35.8
GTEX-ZEX8-0726-SM-4WKH8
50-59 years, male
35.7
GTEX-1HCU7-1426-SM-CNNQK
50-59 years, male
35.7
GTEX-15DYW-1426-SM-6LPIW
60-69 years, female
35.5
GTEX-146FR-1926-SM-5NQA6
60-69 years, female
35.4
GTEX-1QCLZ-1026-SM-E6CR1
60-69 years, female
35.4
GTEX-1AYD5-0226-SM-79ONV
50-59 years, male
35.3
GTEX-O5YT-0926-SM-48TDG
20-29 years, male
35.3
GTEX-WFON-0126-SM-4LVM9
40-49 years, male
35.3
GTEX-1QMI2-1526-SM-EXOJT
60-69 years, male
35.3
GTEX-P4PQ-0926-SM-E9U4D
60-69 years, male
35.3
GTEX-12BJ1-0726-SM-5EGGF
60-69 years, male
35.2
GTEX-15RJ7-0126-SM-6LPJN
40-49 years, male
35.2
GTEX-1IDJE-0126-SM-C1YQ6
50-59 years, female
35.2
GTEX-1LG7Z-0126-SM-EV79V
30-39 years, male
35.2
GTEX-1QP66-0126-SM-EAZ3N
50-59 years, male
35.2
GTEX-R55G-0226-SM-48FEI
40-49 years, female
35.1
GTEX-1399R-0226-SM-5IJGG
30-39 years, male
35.0
GTEX-ZV6S-0826-SM-5NQ6Z
40-49 years, female
34.9
GTEX-1QCLY-0126-SM-DPRZV
30-39 years, male
34.9
GTEX-12WSG-0926-SM-5EGIH
50-59 years, female
34.6
GTEX-13CF3-0226-SM-5J1NW
60-69 years, female
34.6
GTEX-VJYA-0126-SM-4KL1P
60-69 years, male
34.5
GTEX-132QS-0226-SM-5IFFZ
60-69 years, male
34.4
GTEX-111FC-1326-SM-5N9D9
60-69 years, male
34.3
GTEX-X3Y1-0126-SM-4PQZA
40-49 years, male
34.3
GTEX-S4Z8-0226-SM-4AD5K
60-69 years, male
34.2
GTEX-ZLFU-0526-SM-4WWBN
40-49 years, male
34.1
GTEX-ZTTD-1726-SM-57WEL
50-59 years, male
34.0
GTEX-14JG6-0226-SM-6872A
30-39 years, female
33.9
GTEX-18A67-1526-SM-7LG6F
50-59 years, male
33.9
GTEX-QDVN-0526-SM-48TZ4
50-59 years, male
33.9
GTEX-X585-1826-SM-4QAS3
50-59 years, male
33.8
GTEX-XQ8I-1726-SM-4BOQB
50-59 years, male
33.8
GTEX-Y3I4-0126-SM-4TT26
50-59 years, male
33.8
GTEX-14DAR-0326-SM-5S2PS
50-59 years, male
33.7
GTEX-XMK1-0126-SM-4B65F
40-49 years, male
33.7
GTEX-11DXX-0726-SM-5H12X
60-69 years, female
33.3
GTEX-144GN-2126-SM-5O99D
50-59 years, male
33.2
GTEX-T5JW-0126-SM-4DM6K
20-29 years, female
33.2
GTEX-Y8LW-0126-SM-4VBS1
50-59 years, female
33.2
GTEX-ZDYS-1026-SM-4WKHC
50-59 years, male
33.2
GTEX-1C4CL-0626-SM-731DM
30-39 years, male
33.0
GTEX-1MJK3-0126-SM-DPRYY
20-29 years, male
32.9
GTEX-11P81-1326-SM-5GU5S
30-39 years, female
32.8
GTEX-12WSD-1726-SM-5GCN4
60-69 years, female
32.8
GTEX-12WSK-0126-SM-5GCO7
40-49 years, female
32.8
GTEX-13FH7-1326-SM-5IFG8
50-59 years, female
32.8
GTEX-OOBJ-0926-SM-48TDO
60-69 years, male
32.8
GTEX-ZPU1-1026-SM-4YCEQ
40-49 years, male
32.8
GTEX-WY7C-0126-SM-4ONCO
50-59 years, male
32.7
GTEX-1JK1U-0126-SM-C1YQY
60-69 years, male
32.7
GTEX-YEC4-0126-SM-4W21T
40-49 years, male
32.5
GTEX-1JMQK-1126-SM-CXZJW
60-69 years, male
32.5
GTEX-14ICL-0126-SM-664NG
30-39 years, male
32.4
GTEX-XAJ8-0126-SM-47JYG
40-49 years, male
32.3
GTEX-1F5PK-0726-SM-7MGXN
50-59 years, male
32.3
GTEX-1HCU9-0126-SM-9WG7M
20-29 years, male
32.0
GTEX-1S831-0726-SM-EV79O
20-29 years, male
32.0
GTEX-W5WG-0626-SM-4SOID
50-59 years, female
31.9
GTEX-1RAZQ-0126-SM-EV7B1
30-39 years, male
31.9
GTEX-R55C-0126-SM-48FEQ
40-49 years, male
31.9
GTEX-1399S-0226-SM-5IFFG
30-39 years, female
31.8
GTEX-14PKU-0526-SM-6871A
40-49 years, female
31.7
GTEX-P4QS-0926-SM-48TBS
60-69 years, male
31.7
GTEX-XV7Q-0126-SM-4BRVK
40-49 years, female
31.7
GTEX-131XG-0426-SM-5IFGD
50-59 years, female
31.5
GTEX-147F3-0126-SM-5NQBJ
50-59 years, female
31.5
GTEX-16MT9-1726-SM-6M47P
60-69 years, female
31.5
GTEX-Z9EW-0726-SM-5HL9H
40-49 years, male
31.5
GTEX-ZPCL-0626-SM-DNZZ6
60-69 years, female
31.5
GTEX-1R9K4-1526-SM-DPRY5
60-69 years, male
31.4
GTEX-11VI4-0126-SM-5GU6Z
40-49 years, female
31.3
GTEX-14PJ4-0526-SM-6871G
60-69 years, male
31.3
GTEX-QCQG-0226-SM-48U28
50-59 years, female
31.3
GTEX-Y5LM-0326-SM-4VBRN
40-49 years, female
31.3
GTEX-1JMPZ-0926-SM-CXZJR
30-39 years, male
31.3
GTEX-1MGNQ-1126-SM-EAZ4Y
40-49 years, male
31.3
GTEX-1B97J-1926-SM-7IGQB
50-59 years, female
31.2
GTEX-WYJK-0726-SM-4ONC9
50-59 years, male
31.2
GTEX-ZYFG-0726-SM-5GIDX
60-69 years, female
31.2
GTEX-145MN-0126-SM-5RQHY
30-39 years, male
31.1
GTEX-17F9E-1126-SM-79OMO
50-59 years, male
31.1
GTEX-15CHC-0726-SM-6AJ9D
60-69 years, female
31.0
GTEX-1R9PM-0126-SM-DPRY6
20-29 years, male
31.0
GTEX-15SHV-0126-SM-6LPIS
60-69 years, male
30.6
GTEX-1N2EF-1526-SM-EXOIY
60-69 years, male
30.5
GTEX-12WSN-0126-SM-5DUX5
40-49 years, male
30.2
GTEX-169BO-0126-SM-79OLS
50-59 years, male
30.2
GTEX-1RNTQ-1026-SM-EV7B4
20-29 years, female
30.2
GTEX-15DZA-0126-SM-6PAMV
30-39 years, female
30.1
GTEX-WXYG-0126-SM-4OND7
50-59 years, female
30.1
GTEX-17HHE-0326-SM-793BH
50-59 years, male
30.0
GTEX-1J8Q3-0126-SM-C1YSI
60-69 years, male
29.9
GTEX-Q734-0226-SM-48U1A
40-49 years, female
29.8
GTEX-1QP29-0126-SM-EAZ3S
50-59 years, male
29.8
GTEX-QESD-0126-SM-EXOHG
20-29 years, male
29.8
GTEX-131XE-1126-SM-5EGHW
50-59 years, male
29.7
GTEX-1RAZR-1626-SM-EAZ4V
40-49 years, male
29.7
GTEX-17GQL-0126-SM-72D5Q
60-69 years, male
29.6
GTEX-WHWD-0126-SM-4OORS
50-59 years, male
29.6
GTEX-1KD5A-1526-SM-D4P3W
50-59 years, male
29.5
GTEX-1MCC2-0826-SM-EV7AM
30-39 years, female
29.5
GTEX-1B8KZ-0226-SM-7EWF6
50-59 years, male
29.4
GTEX-WYVS-0126-SM-4ONDH
40-49 years, female
29.4
GTEX-1F75I-0226-SM-7MKHQ
40-49 years, male
29.4
GTEX-13PVR-0326-SM-5RQJY
60-69 years, female
29.2
GTEX-15RIF-0526-SM-6LLI2
20-29 years, male
29.2
GTEX-1R7EU-2026-SM-E9U63
60-69 years, male
29.1
GTEX-15F5U-0126-SM-6LPKA
40-49 years, male
29.0
GTEX-14E1K-0126-SM-664NL
50-59 years, male
28.9
GTEX-1L5NE-0926-SM-D4P3P
50-59 years, male
28.9
GTEX-QMRM-0226-SM-CL55S
50-59 years, male
28.9
GTEX-117YX-2126-SM-5GIEL
50-59 years, male
28.8
GTEX-1RMOY-0726-SM-EV79D
50-59 years, male
28.8
GTEX-1FIGZ-0126-SM-7MKGZ
40-49 years, male
28.6
GTEX-14PJ5-0326-SM-664OD
60-69 years, female
28.5
GTEX-ZP4G-0326-SM-4YCEF
20-29 years, female
28.5
GTEX-1C6VQ-2126-SM-7IGNL
50-59 years, male
28.4
GTEX-11LCK-0126-SM-5A5M5
30-39 years, male
28.3
GTEX-15UF7-1926-SM-6LPJT
40-49 years, male
28.3
GTEX-ZLWG-0426-SM-4WWFA
50-59 years, female
28.3
GTEX-11NSD-0426-SM-5N9CR
20-29 years, male
28.2
GTEX-ZDTT-1026-SM-5KM19
60-69 years, male
28.2
GTEX-13111-0126-SM-5EGHO
50-59 years, male
28.1
GTEX-15ER7-1526-SM-6LLHO
20-29 years, female
28.1
GTEX-Y114-0726-SM-4TT6U
50-59 years, female
28.1
GTEX-1LVAN-1026-SM-CNNQZ
50-59 years, female
28.1
GTEX-ZG7Y-2026-SM-DO91N
50-59 years, male
27.7
GTEX-15ETS-3126-SM-6LPKN
40-49 years, female
27.6
GTEX-139T6-0226-SM-5IFGZ
50-59 years, male
27.5
GTEX-15SB6-0126-SM-6LPJR
50-59 years, female
27.4
GTEX-15CHQ-1226-SM-6ETZL
60-69 years, male
27.3
GTEX-1211K-0426-SM-5FQTP
60-69 years, female
27.2
GTEX-15SDE-0126-SM-793BA
50-59 years, female
27.2
GTEX-PW2O-0126-SM-48TC8
20-29 years, male
27.2
GTEX-1B97I-0126-SM-731DH
40-49 years, male
26.9
GTEX-P4PP-0926-SM-48TBZ
30-39 years, female
26.9
GTEX-15RIG-0126-SM-6PAN4
40-49 years, male
26.8
GTEX-17F96-1426-SM-7IGQA
70-79 years, male
26.8
GTEX-111CU-0426-SM-5GZY1
50-59 years, male
26.7
GTEX-YFCO-0926-SM-5LUA5
40-49 years, male
26.6
GTEX-ZF2S-0326-SM-4WKGD
50-59 years, female
26.6
GTEX-1J8QM-0926-SM-C1YQ9
60-69 years, female
26.6
GTEX-YB5E-0426-SM-5IFHR
40-49 years, male
26.5
GTEX-1PWST-1626-SM-EXOIU
70-79 years, male
26.5
GTEX-13VXT-1326-SM-5LU3Y
20-29 years, female
26.4
GTEX-1MCYP-0226-SM-EV7A3
20-29 years, female
26.4
GTEX-13PL7-1126-SM-5MR5O
60-69 years, female
26.1
GTEX-139YR-0426-SM-5IFFV
50-59 years, male
25.9
GTEX-ZZPU-0126-SM-5E446
50-59 years, female
25.9
GTEX-1C475-1126-SM-7MGY7
40-49 years, female
25.8
GTEX-1A3MV-0126-SM-731FQ
30-39 years, male
25.7
GTEX-1IDJC-0126-SM-C1YQC
50-59 years, male
25.7
GTEX-UJHI-0126-SM-4IHLP
50-59 years, female
25.6
GTEX-11EQ9-0426-SM-5A5JY
30-39 years, male
25.5
GTEX-17F98-0126-SM-7MGW3
40-49 years, female
25.5
GTEX-ZVZP-0726-SM-59HKA
50-59 years, male
25.4
GTEX-1CB4E-0126-SM-7DHMX
60-69 years, male
25.2
GTEX-1HSMQ-0126-SM-D4P2I
50-59 years, male
25.1
GTEX-1K2DA-0126-SM-CGQGV
50-59 years, male
24.9
GTEX-1H3VY-1526-SM-9WG7S
50-59 years, male
24.8
GTEX-1R9JW-0126-SM-EAZ4P
30-39 years, female
24.7
GTEX-1AX9K-0226-SM-793CM
50-59 years, male
24.5
GTEX-1LGRB-0126-SM-CNNR6
50-59 years, female
24.5
GTEX-OIZF-0926-SM-7MKH7
60-69 years, male
24.3
GTEX-1JKYN-0326-SM-AHZ4D
30-39 years, male
24.0
GTEX-14BMU-0426-SM-73KYT
20-29 years, female
23.5
GTEX-1LSNM-0126-SM-EAZ57
50-59 years, male
23.3
GTEX-1122O-0526-SM-5N9DM
60-69 years, female
23.2
GTEX-1RAZA-1026-SM-E6CQ9
20-29 years, male
22.7
GTEX-14PN3-0226-SM-6871K
60-69 years, female
22.6
GTEX-PLZ6-0126-SM-48TC6
30-39 years, male
22.6
GTEX-1CB4I-1426-SM-79OLZ
50-59 years, male
22.2
GTEX-1AMFI-0926-SM-731E4
50-59 years, female
21.9
GTEX-XPVG-0626-SM-4B65B
50-59 years, male
21.7
GTEX-ZF29-0626-SM-4WKHD
60-69 years, female
20.9
GTEX-11P7K-0426-SM-5BC5H
30-39 years, male
20.6
GTEX-1GZ4H-0126-SM-9JGGI
50-59 years, female
19.1
GTEX-ZAB5-0526-SM-5CVMU
50-59 years, male
12.0
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SPLEEN - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
The Human Protein Atlas project is funded
