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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cells in red pulp:
Low
Cells in white pulp:
Not detected
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
21.2
nTPM
HPA:
13.5
nTPM
GTEx:
21.2
nTPM
FANTOM5:
88.8
Scaled Tags Per Million
SPLEEN - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA054049
Cells in red pulp
Low
Cells in white pulp
Not detected
SPLEEN - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPM
13.5
Female, age 60
Spleen sample 236 nTPM: 10.1
Cell types%
Lymphocytes:
40
Macrophages:
30
Endothelial cells:
15
Fibroblasts:
5
Other cell types:
10
Male, age 17
Spleen sample 237 nTPM: 14.5
Cell types%
Lymphocytes:
40
Macrophages:
35
Endothelial cells:
15
Fibroblasts:
5
Other cell types:
5
Male, age 20
Spleen sample 238 nTPM: 20.4
Cell types%
Lymphocytes:
40
Macrophages:
30
Endothelial cells:
15
Fibroblasts:
5
Other cell types:
10
Female, age 19
Spleen sample 239 nTPM: 6.6
Cell types%
Lymphocytes:
40
Macrophages:
30
Endothelial cells:
15
Fibroblasts:
10
Other cell types:
5
Female, age 65
Spleen sample 378 nTPM: 15.8
Cell types%
Lymphocytes:
35
Macrophages:
30
Endothelial cells:
20
Fibroblasts:
10
Other cell types:
5
SPLEEN - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Average nTPM
21.2
GTEx sample id
Sample description
nTPM
Spleen Average nTPM: 21.2
Samples: 241
Max nTPM: 89.0
Min nTPM: 2.7
Std nTPM: 17.3
Median nTPM: 15.0
GTEX-Y3IK-0126-SM-4WWE9
50-59 years, female
89.0
GTEX-13OVK-0426-SM-7KFT8
40-49 years, male
85.3
GTEX-1A3MV-0126-SM-731FQ
30-39 years, male
83.2
GTEX-13U4I-1626-SM-5IFFR
40-49 years, female
80.8
GTEX-12WSK-0126-SM-5GCO7
40-49 years, female
78.4
GTEX-15CHC-0726-SM-6AJ9D
60-69 years, female
74.9
GTEX-1HCU7-1426-SM-CNNQK
50-59 years, male
73.7
GTEX-Q734-0226-SM-48U1A
40-49 years, female
73.6
GTEX-18A66-1826-SM-7KFSU
60-69 years, male
63.1
GTEX-14PJ6-0226-SM-6AJ9K
60-69 years, female
62.8
GTEX-1QCLY-0126-SM-DPRZV
30-39 years, male
61.6
GTEX-169BO-0126-SM-79OLS
50-59 years, male
60.9
GTEX-QV44-0126-SM-CJI1X
50-59 years, male
59.2
GTEX-1QAET-2326-SM-EXOJ1
50-59 years, male
56.8
GTEX-139YR-0426-SM-5IFFV
50-59 years, male
55.2
GTEX-1QP66-0126-SM-EAZ3N
50-59 years, male
55.2
GTEX-1RAZA-1026-SM-E6CQ9
20-29 years, male
54.9
GTEX-1R9JW-0126-SM-EAZ4P
30-39 years, female
54.7
GTEX-PX3G-0926-SM-48U12
20-29 years, female
52.2
GTEX-1QP29-0126-SM-EAZ3S
50-59 years, male
48.7
GTEX-P4PP-0926-SM-48TBZ
30-39 years, female
48.2
GTEX-PW2O-0126-SM-48TC8
20-29 years, male
48.2
GTEX-117YX-2126-SM-5GIEL
50-59 years, male
46.7
GTEX-15DZA-0126-SM-6PAMV
30-39 years, female
46.6
GTEX-1399R-0226-SM-5IJGG
30-39 years, male
46.0
GTEX-13VXT-1326-SM-5LU3Y
20-29 years, female
45.9
GTEX-1IDJC-0126-SM-C1YQC
50-59 years, male
45.8
GTEX-1C4CL-0626-SM-731DM
30-39 years, male
45.6
GTEX-1JK1U-0126-SM-C1YQY
60-69 years, male
44.5
GTEX-1MCC2-0826-SM-EV7AM
30-39 years, female
44.5
GTEX-15SB6-0126-SM-6LPJR
50-59 years, female
44.3
GTEX-ZF2S-0326-SM-4WKGD
50-59 years, female
43.3
GTEX-WYVS-0126-SM-4ONDH
40-49 years, female
41.0
GTEX-1RNTQ-1026-SM-EV7B4
20-29 years, female
40.2
GTEX-11VI4-0126-SM-5GU6Z
40-49 years, female
39.0
GTEX-1IDJE-0126-SM-C1YQ6
50-59 years, female
39.0
GTEX-Y114-0726-SM-4TT6U
50-59 years, female
37.8
GTEX-145MN-0126-SM-5RQHY
30-39 years, male
35.7
GTEX-Y5V5-1126-SM-EVYAR
60-69 years, female
35.2
GTEX-1B97J-1926-SM-7IGQB
50-59 years, female
34.6
GTEX-UPK5-1626-SM-4JBHI
40-49 years, male
32.9
GTEX-1CB4F-0226-SM-7EPHS
60-69 years, male
32.2
GTEX-1N2EF-1526-SM-EXOIY
60-69 years, male
31.8
GTEX-1JMQK-1126-SM-CXZJW
60-69 years, male
31.6
GTEX-1LGRB-0126-SM-CNNR6
50-59 years, female
31.4
GTEX-146FQ-0626-SM-5LU9U
30-39 years, male
31.0
GTEX-QDT8-1526-SM-EXOHP
30-39 years, female
30.5
GTEX-14ICL-0126-SM-664NG
30-39 years, male
30.4
GTEX-13PL7-1126-SM-5MR5O
60-69 years, female
29.6
GTEX-1B8KZ-0226-SM-7EWF6
50-59 years, male
29.6
GTEX-X585-1826-SM-4QAS3
50-59 years, male
29.5
GTEX-ZLWG-0426-SM-4WWFA
50-59 years, female
29.1
GTEX-1LG7Z-0126-SM-EV79V
30-39 years, male
28.9
GTEX-1LVAN-1026-SM-CNNQZ
50-59 years, female
28.4
GTEX-P4QT-0926-SM-EZ6KQ
50-59 years, female
28.0
GTEX-U3ZH-0126-SM-4DXUK
30-39 years, male
27.5
GTEX-Y8LW-0126-SM-4VBS1
50-59 years, female
27.3
GTEX-1JMLX-1426-SM-CNNPO
50-59 years, male
27.2
GTEX-15UF7-1926-SM-6LPJT
40-49 years, male
26.7
GTEX-1H3VY-1526-SM-9WG7S
50-59 years, male
26.5
GTEX-1R7EV-0126-SM-EAZ3O
40-49 years, male
26.4
GTEX-OOBJ-0926-SM-48TDO
60-69 years, male
26.3
GTEX-1AYD5-0226-SM-79ONV
50-59 years, male
25.9
GTEX-POMQ-0126-SM-48TD6
20-29 years, female
24.8
GTEX-11P7K-0426-SM-5BC5H
30-39 years, male
24.1
GTEX-P4PQ-0926-SM-E9U4D
60-69 years, male
23.9
GTEX-ZAB5-0526-SM-5CVMU
50-59 years, male
23.4
GTEX-R55G-0226-SM-48FEI
40-49 years, female
23.2
GTEX-WYJK-0726-SM-4ONC9
50-59 years, male
22.8
GTEX-ZEX8-0726-SM-4WKH8
50-59 years, male
22.5
GTEX-ZLFU-0526-SM-4WWBN
40-49 years, male
22.4
GTEX-14DAR-0326-SM-5S2PS
50-59 years, male
22.2
GTEX-1AMFI-0926-SM-731E4
50-59 years, female
21.5
GTEX-YB5E-0426-SM-5IFHR
40-49 years, male
21.5
GTEX-15SDE-0126-SM-793BA
50-59 years, female
21.2
GTEX-1F5PK-0726-SM-7MGXN
50-59 years, male
21.2
GTEX-1MGNQ-1126-SM-EAZ4Y
40-49 years, male
21.2
GTEX-131XE-1126-SM-5EGHW
50-59 years, male
21.0
GTEX-17HHE-0326-SM-793BH
50-59 years, male
21.0
GTEX-XQ8I-1726-SM-4BOQB
50-59 years, male
20.9
GTEX-1RAZQ-0126-SM-EV7B1
30-39 years, male
20.9
GTEX-13N11-0126-SM-5KM2Z
50-59 years, female
20.8
GTEX-ZV6S-0826-SM-5NQ6Z
40-49 years, female
20.8
GTEX-13CF3-0226-SM-5J1NW
60-69 years, female
20.4
GTEX-P78B-1226-SM-EZ6KP
40-49 years, female
20.4
GTEX-1KAFJ-1026-SM-D4P2Z
50-59 years, male
20.2
GTEX-QESD-0126-SM-EXOHG
20-29 years, male
20.1
GTEX-17F9E-1126-SM-79OMO
50-59 years, male
19.7
GTEX-YFCO-0926-SM-5LUA5
40-49 years, male
19.2
GTEX-1R9K4-1526-SM-DPRY5
60-69 years, male
18.6
GTEX-139T6-0226-SM-5IFGZ
50-59 years, male
18.5
GTEX-1F75I-0226-SM-7MKHQ
40-49 years, male
18.2
GTEX-1399S-0226-SM-5IFFG
30-39 years, female
18.1
GTEX-16MT8-1826-SM-7EWE8
60-69 years, female
18.1
GTEX-QDVN-0526-SM-48TZ4
50-59 years, male
18.1
GTEX-WY7C-0126-SM-4ONCO
50-59 years, male
18.0
GTEX-1MUQO-1326-SM-EV7AE
60-69 years, male
17.9
GTEX-1RMOY-0726-SM-EV79D
50-59 years, male
17.9
GTEX-146FR-1926-SM-5NQA6
60-69 years, female
17.7
GTEX-1R7EU-2026-SM-E9U63
60-69 years, male
17.7
GTEX-15CHQ-1226-SM-6ETZL
60-69 years, male
17.5
GTEX-13FH7-1326-SM-5IFG8
50-59 years, female
17.3
GTEX-15ETS-3126-SM-6LPKN
40-49 years, female
17.3
GTEX-17F97-1626-SM-72D6W
50-59 years, male
17.3
GTEX-XV7Q-0126-SM-4BRVK
40-49 years, female
17.3
GTEX-13111-0126-SM-5EGHO
50-59 years, male
16.5
GTEX-OIZF-0926-SM-7MKH7
60-69 years, male
16.2
GTEX-1LSNM-0126-SM-EAZ57
50-59 years, male
16.1
GTEX-1F5PL-2226-SM-7MKHE
40-49 years, female
16.0
GTEX-1OFPY-0126-SM-EXOJ3
60-69 years, male
15.8
GTEX-11P81-1326-SM-5GU5S
30-39 years, female
15.7
GTEX-14JG6-0226-SM-6872A
30-39 years, female
15.7
GTEX-17GQL-0126-SM-72D5Q
60-69 years, male
15.7
GTEX-13S86-0126-SM-5S2PI
40-49 years, male
15.5
GTEX-Y3I4-0126-SM-4TT26
50-59 years, male
15.4
GTEX-1JMPZ-0926-SM-CXZJR
30-39 years, male
15.3
GTEX-14E1K-0126-SM-664NL
50-59 years, male
15.2
GTEX-U3ZN-0126-SM-4DXUM
30-39 years, female
15.2
GTEX-WXYG-0126-SM-4OND7
50-59 years, female
15.2
GTEX-1C64O-1626-SM-731EN
60-69 years, male
15.1
GTEX-14E6E-1226-SM-5S2R5
30-39 years, male
15.0
GTEX-ZF29-0626-SM-4WKHD
60-69 years, female
15.0
GTEX-1H3O1-1126-SM-9WPO9
60-69 years, male
15.0
GTEX-11EQ9-0426-SM-5A5JY
30-39 years, male
14.9
GTEX-1L5NE-0926-SM-D4P3P
50-59 years, male
14.9
GTEX-S3XE-0626-SM-4AD6B
50-59 years, male
14.8
GTEX-ZP4G-0326-SM-4YCEF
20-29 years, female
14.5
GTEX-1QCLZ-1026-SM-E6CR1
60-69 years, female
14.5
GTEX-12WSG-0926-SM-5EGIH
50-59 years, female
14.4
GTEX-12WSN-0126-SM-5DUX5
40-49 years, male
14.4
GTEX-11LCK-0126-SM-5A5M5
30-39 years, male
14.2
GTEX-NFK9-1426-SM-43ISG
40-49 years, male
14.1
GTEX-O5YT-0926-SM-48TDG
20-29 years, male
13.9
GTEX-ZDYS-1026-SM-4WKHC
50-59 years, male
13.9
GTEX-1S831-0726-SM-EV79O
20-29 years, male
13.9
GTEX-15RJ7-0126-SM-6LPJN
40-49 years, male
13.7
GTEX-ZZPU-0126-SM-5E446
50-59 years, female
13.7
GTEX-QCQG-0226-SM-48U28
50-59 years, female
13.5
GTEX-14PN3-0226-SM-6871K
60-69 years, female
13.3
GTEX-1C475-1126-SM-7MGY7
40-49 years, female
13.3
GTEX-1HSMQ-0126-SM-D4P2I
50-59 years, male
13.2
GTEX-1J8QM-0926-SM-C1YQ9
60-69 years, female
13.2
GTEX-132QS-0226-SM-5IFFZ
60-69 years, male
13.1
GTEX-11NSD-0426-SM-5N9CR
20-29 years, male
13.0
GTEX-1GZ4H-0126-SM-9JGGI
50-59 years, female
12.7
GTEX-15RIG-0126-SM-6PAN4
40-49 years, male
12.4
GTEX-XMK1-0126-SM-4B65F
40-49 years, male
12.3
GTEX-1R9K5-1126-SM-EAZ4G
50-59 years, male
12.3
GTEX-1B97I-0126-SM-731DH
40-49 years, male
12.1
GTEX-WFON-0126-SM-4LVM9
40-49 years, male
12.0
GTEX-ZVP2-0526-SM-51MSC
50-59 years, male
12.0
GTEX-1JKYN-0326-SM-AHZ4D
30-39 years, male
11.9
GTEX-1122O-0526-SM-5N9DM
60-69 years, female
11.8
GTEX-18A67-1526-SM-7LG6F
50-59 years, male
11.8
GTEX-UJHI-0126-SM-4IHLP
50-59 years, female
11.6
GTEX-12BJ1-0726-SM-5EGGF
60-69 years, male
11.5
GTEX-14PK6-0526-SM-69LOF
70-79 years, female
11.4
GTEX-S4Z8-0226-SM-4AD5K
60-69 years, male
11.4
GTEX-17F96-1426-SM-7IGQA
70-79 years, male
11.3
GTEX-ZTTD-1726-SM-57WEL
50-59 years, male
11.2
GTEX-14BMU-0426-SM-73KYT
20-29 years, female
11.1
GTEX-1HCU9-0126-SM-9WG7M
20-29 years, male
11.1
GTEX-RUSQ-0126-SM-47JWV
50-59 years, male
11.0
GTEX-1GF9U-0126-SM-AHZ4G
40-49 years, female
10.9
GTEX-P4QS-0926-SM-48TBS
60-69 years, male
10.8
GTEX-1CB4E-0126-SM-7DHMX
60-69 years, male
10.7
GTEX-1K2DA-0126-SM-CGQGV
50-59 years, male
10.7
GTEX-1MCYP-0226-SM-EV7A3
20-29 years, female
10.7
GTEX-1JKYR-1126-SM-CGQGJ
20-29 years, male
10.6
GTEX-111CU-0426-SM-5GZY1
50-59 years, male
10.5
GTEX-14PJ4-0526-SM-6871G
60-69 years, male
10.4
GTEX-X4LF-0226-SM-4QAS8
50-59 years, male
10.3
GTEX-ZYFG-0726-SM-5GIDX
60-69 years, female
10.3
GTEX-1PDJ9-0226-SM-DPRYX
20-29 years, male
10.3
GTEX-OIZH-0926-SM-48TBR
50-59 years, male
10.0
GTEX-1211K-0426-SM-5FQTP
60-69 years, female
9.9
GTEX-XGQ4-0126-SM-4AT4H
50-59 years, male
9.9
GTEX-1PWST-1626-SM-EXOIU
70-79 years, male
9.9
GTEX-13X6H-0726-SM-5Q5BX
50-59 years, female
9.8
GTEX-R55C-0126-SM-48FEQ
40-49 years, male
9.8
GTEX-XXEK-0126-SM-4BRVU
50-59 years, male
9.7
GTEX-12WSD-1726-SM-5GCN4
60-69 years, female
9.6
GTEX-14PJ5-0326-SM-664OD
60-69 years, female
9.5
GTEX-Q2AH-0226-SM-48U1I
40-49 years, male
9.5
GTEX-1CB4I-1426-SM-79OLZ
50-59 years, male
9.4
GTEX-14PKU-0526-SM-6871A
40-49 years, female
9.3
GTEX-ZPIC-0126-SM-DNZZ9
40-49 years, female
9.3
GTEX-13PVR-0326-SM-5RQJY
60-69 years, female
9.2
GTEX-15F5U-0126-SM-6LPKA
40-49 years, male
9.1
GTEX-VJYA-0126-SM-4KL1P
60-69 years, male
9.1
GTEX-XAJ8-0126-SM-47JYG
40-49 years, male
9.0
GTEX-16XZY-0126-SM-7IGQ9
70-79 years, male
8.9
GTEX-17F98-0126-SM-7MGW3
40-49 years, female
8.9
GTEX-1LSVX-1426-SM-DHXJO
60-69 years, male
8.9
GTEX-144GN-2126-SM-5O99D
50-59 years, male
8.8
GTEX-QLQW-0126-SM-447BK
30-39 years, male
8.8
GTEX-W5WG-0626-SM-4SOID
50-59 years, female
8.8
GTEX-1KD5A-1526-SM-D4P3W
50-59 years, male
8.8
GTEX-ZPCL-0626-SM-DNZZ6
60-69 years, female
8.8
GTEX-1AX9K-0226-SM-793CM
50-59 years, male
8.5
GTEX-YEC4-0126-SM-4W21T
40-49 years, male
8.4
GTEX-ZVZP-0726-SM-59HKA
50-59 years, male
8.4
GTEX-15SHV-0126-SM-6LPIS
60-69 years, male
8.2
GTEX-147F3-0126-SM-5NQBJ
50-59 years, female
8.1
GTEX-U4B1-0526-SM-4DXTK
40-49 years, male
8.1
GTEX-1RAZR-1626-SM-EAZ4V
40-49 years, male
8.1
GTEX-QV31-0126-SM-447BP
30-39 years, male
8.0
GTEX-Z9EW-0726-SM-5HL9H
40-49 years, male
8.0
GTEX-11XUK-0426-SM-5EQML
40-49 years, female
7.9
GTEX-1QW4Y-0126-SM-DPRZQ
30-39 years, male
7.8
GTEX-1PIIG-1226-SM-EXOIQ
30-39 years, male
7.7
GTEX-ZG7Y-2026-SM-DO91N
50-59 years, male
7.5
GTEX-X3Y1-0126-SM-4PQZA
40-49 years, male
7.4
GTEX-Y5LM-0326-SM-4VBRN
40-49 years, female
7.4
GTEX-PLZ6-0126-SM-48TC6
30-39 years, male
7.3
GTEX-WHWD-0126-SM-4OORS
50-59 years, male
7.3
GTEX-131XG-0426-SM-5IFGD
50-59 years, female
7.2
GTEX-1KANA-1226-SM-DHXKE
20-29 years, male
7.2
GTEX-1R9PM-0126-SM-DPRY6
20-29 years, male
7.2
GTEX-YB5K-1926-SM-4VDT4
40-49 years, female
6.8
GTEX-1J8Q3-0126-SM-C1YSI
60-69 years, male
6.8
GTEX-XPVG-0626-SM-4B65B
50-59 years, male
6.6
GTEX-1QMI2-1526-SM-EXOJT
60-69 years, male
6.5
GTEX-1MJK3-0126-SM-DPRYY
20-29 years, male
6.4
GTEX-QMRM-0226-SM-CL55S
50-59 years, male
6.3
GTEX-11DXX-0726-SM-5H12X
60-69 years, female
6.1
GTEX-T5JW-0126-SM-4DM6K
20-29 years, female
5.8
GTEX-1K9T9-0626-SM-CXZKY
50-59 years, female
5.8
GTEX-1QP2A-2526-SM-EXOJB
50-59 years, male
5.8
GTEX-ZDTT-1026-SM-5KM19
60-69 years, male
5.7
GTEX-ZPU1-1026-SM-4YCEQ
40-49 years, male
5.5
GTEX-1LNCM-0426-SM-DHXK6
50-59 years, female
5.5
GTEX-1PPH7-0126-SM-E6CPB
40-49 years, male
4.5
GTEX-15ER7-1526-SM-6LLHO
20-29 years, female
4.2
GTEX-111FC-1326-SM-5N9D9
60-69 years, male
4.1
GTEX-15DYW-1426-SM-6LPIW
60-69 years, female
4.1
GTEX-12WSJ-0526-SM-5GCOZ
40-49 years, female
3.7
GTEX-1C6VQ-2126-SM-7IGNL
50-59 years, male
3.0
GTEX-15RIF-0526-SM-6LLI2
20-29 years, male
2.9
GTEX-1FIGZ-0126-SM-7MKGZ
40-49 years, male
2.8
GTEX-16MT9-1726-SM-6M47P
60-69 years, female
2.7
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SPLEEN - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
The Human Protein Atlas project is funded
