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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cells in red pulp:
Low
Cells in white pulp:
Low
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
21.0
nTPM
HPA:
21.0
nTPM
GTEx:
11.0
nTPM
FANTOM5:
54.5
Scaled Tags Per Million
SPLEEN - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA018911
Antibody CAB025581
Cells in red pulp
Low
Low
Cells in white pulp
Low
Medium
SPLEEN - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPM
21.0
Female, age 60
Spleen sample 236 nTPM: 20.4
Cell types%
Lymphocytes:
40
Macrophages:
30
Endothelial cells:
15
Fibroblasts:
5
Other cell types:
10
Male, age 17
Spleen sample 237 nTPM: 16.4
Cell types%
Lymphocytes:
40
Macrophages:
35
Endothelial cells:
15
Fibroblasts:
5
Other cell types:
5
Male, age 20
Spleen sample 238 nTPM: 16.9
Cell types%
Lymphocytes:
40
Macrophages:
30
Endothelial cells:
15
Fibroblasts:
5
Other cell types:
10
Female, age 19
Spleen sample 239 nTPM: 19.7
Cell types%
Lymphocytes:
40
Macrophages:
30
Endothelial cells:
15
Fibroblasts:
10
Other cell types:
5
Female, age 65
Spleen sample 378 nTPM: 31.6
Cell types%
Lymphocytes:
35
Macrophages:
30
Endothelial cells:
20
Fibroblasts:
10
Other cell types:
5
SPLEEN - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Average nTPM
11.0
GTEx sample id
Sample description
nTPM
Spleen Average nTPM: 11.0
Samples: 241
Max nTPM: 22.1
Min nTPM: 4.8
Std nTPM: 2.9
Median nTPM: 10.7
GTEX-1GZ4H-0126-SM-9JGGI
50-59 years, female
22.1
GTEX-1JMPZ-0926-SM-CXZJR
30-39 years, male
20.8
GTEX-1RAZA-1026-SM-E6CQ9
20-29 years, male
20.4
GTEX-1LSNM-0126-SM-EAZ57
50-59 years, male
20.3
GTEX-1C6VQ-2126-SM-7IGNL
50-59 years, male
19.7
GTEX-1PWST-1626-SM-EXOIU
70-79 years, male
19.2
GTEX-17F96-1426-SM-7IGQA
70-79 years, male
19.1
GTEX-ZF29-0626-SM-4WKHD
60-69 years, female
18.0
GTEX-Y114-0726-SM-4TT6U
50-59 years, female
17.3
GTEX-1R9K4-1526-SM-DPRY5
60-69 years, male
16.9
GTEX-15CHQ-1226-SM-6ETZL
60-69 years, male
16.7
GTEX-16MT9-1726-SM-6M47P
60-69 years, female
16.6
GTEX-11EQ9-0426-SM-5A5JY
30-39 years, male
16.1
GTEX-131XG-0426-SM-5IFGD
50-59 years, female
16.1
GTEX-1LVAN-1026-SM-CNNQZ
50-59 years, female
16.1
GTEX-1C475-1126-SM-7MGY7
40-49 years, female
15.9
GTEX-1PPH7-0126-SM-E6CPB
40-49 years, male
15.9
GTEX-X585-1826-SM-4QAS3
50-59 years, male
15.5
GTEX-1R7EU-2026-SM-E9U63
60-69 years, male
15.4
GTEX-111FC-1326-SM-5N9D9
60-69 years, male
15.3
GTEX-1MCYP-0226-SM-EV7A3
20-29 years, female
15.1
GTEX-1QMI2-1526-SM-EXOJT
60-69 years, male
15.0
GTEX-14PN3-0226-SM-6871K
60-69 years, female
14.9
GTEX-YB5E-0426-SM-5IFHR
40-49 years, male
14.7
GTEX-1KD5A-1526-SM-D4P3W
50-59 years, male
14.6
GTEX-139T6-0226-SM-5IFGZ
50-59 years, male
14.4
GTEX-ZTTD-1726-SM-57WEL
50-59 years, male
14.3
GTEX-1CB4E-0126-SM-7DHMX
60-69 years, male
14.1
GTEX-1JKYN-0326-SM-AHZ4D
30-39 years, male
14.1
GTEX-ZG7Y-2026-SM-DO91N
50-59 years, male
14.1
GTEX-14E1K-0126-SM-664NL
50-59 years, male
14.0
GTEX-15SDE-0126-SM-793BA
50-59 years, female
14.0
GTEX-XV7Q-0126-SM-4BRVK
40-49 years, female
14.0
GTEX-1B97J-1926-SM-7IGQB
50-59 years, female
13.9
GTEX-15ER7-1526-SM-6LLHO
20-29 years, female
13.8
GTEX-1H3VY-1526-SM-9WG7S
50-59 years, male
13.8
GTEX-1R9JW-0126-SM-EAZ4P
30-39 years, female
13.8
GTEX-1211K-0426-SM-5FQTP
60-69 years, female
13.7
GTEX-13PVR-0326-SM-5RQJY
60-69 years, female
13.7
GTEX-17F97-1626-SM-72D6W
50-59 years, male
13.7
GTEX-1LG7Z-0126-SM-EV79V
30-39 years, male
13.6
GTEX-11P7K-0426-SM-5BC5H
30-39 years, male
13.5
GTEX-1AMFI-0926-SM-731E4
50-59 years, female
13.5
GTEX-1RMOY-0726-SM-EV79D
50-59 years, male
13.5
GTEX-15RIF-0526-SM-6LLI2
20-29 years, male
13.4
GTEX-1RNTQ-1026-SM-EV7B4
20-29 years, female
13.3
GTEX-17GQL-0126-SM-72D5Q
60-69 years, male
13.2
GTEX-1C4CL-0626-SM-731DM
30-39 years, male
13.1
GTEX-1HSMQ-0126-SM-D4P2I
50-59 years, male
13.1
GTEX-17F9E-1126-SM-79OMO
50-59 years, male
13.0
GTEX-YFCO-0926-SM-5LUA5
40-49 years, male
13.0
GTEX-1LNCM-0426-SM-DHXK6
50-59 years, female
13.0
GTEX-14BMU-0426-SM-73KYT
20-29 years, female
12.9
GTEX-1F75I-0226-SM-7MKHQ
40-49 years, male
12.9
GTEX-1JMQK-1126-SM-CXZJW
60-69 years, male
12.9
GTEX-1K2DA-0126-SM-CGQGV
50-59 years, male
12.9
GTEX-15ETS-3126-SM-6LPKN
40-49 years, female
12.7
GTEX-1LGRB-0126-SM-CNNR6
50-59 years, female
12.7
GTEX-1CB4I-1426-SM-79OLZ
50-59 years, male
12.6
GTEX-1FIGZ-0126-SM-7MKGZ
40-49 years, male
12.6
GTEX-P4PP-0926-SM-48TBZ
30-39 years, female
12.6
GTEX-S3XE-0626-SM-4AD6B
50-59 years, male
12.6
GTEX-111CU-0426-SM-5GZY1
50-59 years, male
12.5
GTEX-R55G-0226-SM-48FEI
40-49 years, female
12.5
GTEX-UJHI-0126-SM-4IHLP
50-59 years, female
12.4
GTEX-Q734-0226-SM-48U1A
40-49 years, female
12.3
GTEX-ZLWG-0426-SM-4WWFA
50-59 years, female
12.3
GTEX-PLZ6-0126-SM-48TC6
30-39 years, male
12.2
GTEX-POMQ-0126-SM-48TD6
20-29 years, female
12.2
GTEX-14E6E-1226-SM-5S2R5
30-39 years, male
12.1
GTEX-W5WG-0626-SM-4SOID
50-59 years, female
12.1
GTEX-ZAB5-0526-SM-5CVMU
50-59 years, male
12.1
GTEX-1L5NE-0926-SM-D4P3P
50-59 years, male
12.1
GTEX-132QS-0226-SM-5IFFZ
60-69 years, male
12.0
GTEX-14ICL-0126-SM-664NG
30-39 years, male
12.0
GTEX-WHWD-0126-SM-4OORS
50-59 years, male
12.0
GTEX-ZVZP-0726-SM-59HKA
50-59 years, male
12.0
GTEX-13OVK-0426-SM-7KFT8
40-49 years, male
11.9
GTEX-15CHC-0726-SM-6AJ9D
60-69 years, female
11.9
GTEX-ZPU1-1026-SM-4YCEQ
40-49 years, male
11.9
GTEX-1IDJC-0126-SM-C1YQC
50-59 years, male
11.9
GTEX-12WSG-0926-SM-5EGIH
50-59 years, female
11.8
GTEX-1399S-0226-SM-5IFFG
30-39 years, female
11.8
GTEX-13PL7-1126-SM-5MR5O
60-69 years, female
11.8
GTEX-XPVG-0626-SM-4B65B
50-59 years, male
11.8
GTEX-1MCC2-0826-SM-EV7AM
30-39 years, female
11.8
GTEX-1N2EF-1526-SM-EXOIY
60-69 years, male
11.8
GTEX-15DZA-0126-SM-6PAMV
30-39 years, female
11.7
GTEX-ZDTT-1026-SM-5KM19
60-69 years, male
11.7
GTEX-OIZF-0926-SM-7MKH7
60-69 years, male
11.7
GTEX-1122O-0526-SM-5N9DM
60-69 years, female
11.6
GTEX-13VXT-1326-SM-5LU3Y
20-29 years, female
11.5
GTEX-169BO-0126-SM-79OLS
50-59 years, male
11.5
GTEX-14PJ4-0526-SM-6871G
60-69 years, male
11.4
GTEX-14PKU-0526-SM-6871A
40-49 years, female
11.4
GTEX-1J8Q3-0126-SM-C1YSI
60-69 years, male
11.4
GTEX-1J8QM-0926-SM-C1YQ9
60-69 years, female
11.4
GTEX-15F5U-0126-SM-6LPKA
40-49 years, male
11.3
GTEX-WXYG-0126-SM-4OND7
50-59 years, female
11.3
GTEX-ZPCL-0626-SM-DNZZ6
60-69 years, female
11.3
GTEX-13S86-0126-SM-5S2PI
40-49 years, male
11.2
GTEX-1MGNQ-1126-SM-EAZ4Y
40-49 years, male
11.2
GTEX-139YR-0426-SM-5IFFV
50-59 years, male
11.1
GTEX-14PJ5-0326-SM-664OD
60-69 years, female
11.1
GTEX-1B97I-0126-SM-731DH
40-49 years, male
11.1
GTEX-YB5K-1926-SM-4VDT4
40-49 years, female
11.1
GTEX-15UF7-1926-SM-6LPJT
40-49 years, male
11.0
GTEX-ZYFG-0726-SM-5GIDX
60-69 years, female
11.0
GTEX-1K9T9-0626-SM-CXZKY
50-59 years, female
11.0
GTEX-12BJ1-0726-SM-5EGGF
60-69 years, male
10.9
GTEX-1HCU9-0126-SM-9WG7M
20-29 years, male
10.9
GTEX-1QAET-2326-SM-EXOJ1
50-59 years, male
10.9
GTEX-QMRM-0226-SM-CL55S
50-59 years, male
10.9
GTEX-11VI4-0126-SM-5GU6Z
40-49 years, female
10.8
GTEX-12WSD-1726-SM-5GCN4
60-69 years, female
10.8
GTEX-16MT8-1826-SM-7EWE8
60-69 years, female
10.8
GTEX-17HHE-0326-SM-793BH
50-59 years, male
10.8
GTEX-1AX9K-0226-SM-793CM
50-59 years, male
10.8
GTEX-1JMLX-1426-SM-CNNPO
50-59 years, male
10.8
GTEX-1RAZR-1626-SM-EAZ4V
40-49 years, male
10.8
GTEX-ZLFU-0526-SM-4WWBN
40-49 years, male
10.7
GTEX-QDT8-1526-SM-EXOHP
30-39 years, female
10.7
GTEX-Y5V5-1126-SM-EVYAR
60-69 years, female
10.7
GTEX-15SB6-0126-SM-6LPJR
50-59 years, female
10.6
GTEX-OIZH-0926-SM-48TBR
50-59 years, male
10.6
GTEX-1KAFJ-1026-SM-D4P2Z
50-59 years, male
10.6
GTEX-1LSVX-1426-SM-DHXJO
60-69 years, male
10.5
GTEX-11DXX-0726-SM-5H12X
60-69 years, female
10.4
GTEX-14JG6-0226-SM-6872A
30-39 years, female
10.4
GTEX-1HCU7-1426-SM-CNNQK
50-59 years, male
10.4
GTEX-147F3-0126-SM-5NQBJ
50-59 years, female
10.3
GTEX-15SHV-0126-SM-6LPIS
60-69 years, male
10.3
GTEX-1MJK3-0126-SM-DPRYY
20-29 years, male
10.3
GTEX-1PIIG-1226-SM-EXOIQ
30-39 years, male
10.3
GTEX-13111-0126-SM-5EGHO
50-59 years, male
10.2
GTEX-P4QS-0926-SM-48TBS
60-69 years, male
10.2
GTEX-VJYA-0126-SM-4KL1P
60-69 years, male
10.2
GTEX-X4LF-0226-SM-4QAS8
50-59 years, male
10.2
GTEX-1A3MV-0126-SM-731FQ
30-39 years, male
10.1
GTEX-S4Z8-0226-SM-4AD5K
60-69 years, male
10.1
GTEX-117YX-2126-SM-5GIEL
50-59 years, male
10.0
GTEX-Y5LM-0326-SM-4VBRN
40-49 years, female
10.0
GTEX-1JK1U-0126-SM-C1YQY
60-69 years, male
10.0
GTEX-1QP29-0126-SM-EAZ3S
50-59 years, male
10.0
GTEX-11P81-1326-SM-5GU5S
30-39 years, female
9.9
GTEX-ZF2S-0326-SM-4WKGD
50-59 years, female
9.9
GTEX-NFK9-1426-SM-43ISG
40-49 years, male
9.9
GTEX-PW2O-0126-SM-48TC8
20-29 years, male
9.8
GTEX-1S831-0726-SM-EV79O
20-29 years, male
9.8
GTEX-13CF3-0226-SM-5J1NW
60-69 years, female
9.7
GTEX-QDVN-0526-SM-48TZ4
50-59 years, male
9.7
GTEX-RUSQ-0126-SM-47JWV
50-59 years, male
9.7
GTEX-WYVS-0126-SM-4ONDH
40-49 years, female
9.7
GTEX-Z9EW-0726-SM-5HL9H
40-49 years, male
9.7
GTEX-WYJK-0726-SM-4ONC9
50-59 years, male
9.6
GTEX-R55C-0126-SM-48FEQ
40-49 years, male
9.6
GTEX-U4B1-0526-SM-4DXTK
40-49 years, male
9.5
GTEX-17F98-0126-SM-7MGW3
40-49 years, female
9.5
GTEX-QESD-0126-SM-EXOHG
20-29 years, male
9.5
GTEX-14DAR-0326-SM-5S2PS
50-59 years, male
9.4
GTEX-15RIG-0126-SM-6PAN4
40-49 years, male
9.4
GTEX-UPK5-1626-SM-4JBHI
40-49 years, male
9.4
GTEX-X3Y1-0126-SM-4PQZA
40-49 years, male
9.4
GTEX-11XUK-0426-SM-5EQML
40-49 years, female
9.3
GTEX-12WSN-0126-SM-5DUX5
40-49 years, male
9.3
GTEX-13FH7-1326-SM-5IFG8
50-59 years, female
9.3
GTEX-145MN-0126-SM-5RQHY
30-39 years, male
9.3
GTEX-18A67-1526-SM-7LG6F
50-59 years, male
9.3
GTEX-WFON-0126-SM-4LVM9
40-49 years, male
9.3
GTEX-144GN-2126-SM-5O99D
50-59 years, male
9.2
GTEX-QCQG-0226-SM-48U28
50-59 years, female
9.2
GTEX-ZV6S-0826-SM-5NQ6Z
40-49 years, female
9.2
GTEX-ZZPU-0126-SM-5E446
50-59 years, female
9.2
GTEX-1H3O1-1126-SM-9WPO9
60-69 years, male
9.2
GTEX-1QP2A-2526-SM-EXOJB
50-59 years, male
9.1
GTEX-1RAZQ-0126-SM-EV7B1
30-39 years, male
9.1
GTEX-14PK6-0526-SM-69LOF
70-79 years, female
9.0
GTEX-15DYW-1426-SM-6LPIW
60-69 years, female
9.0
GTEX-1C64O-1626-SM-731EN
60-69 years, male
9.0
GTEX-Y3I4-0126-SM-4TT26
50-59 years, male
9.0
GTEX-ZVP2-0526-SM-51MSC
50-59 years, male
9.0
GTEX-1MUQO-1326-SM-EV7AE
60-69 years, male
9.0
GTEX-ZEX8-0726-SM-4WKH8
50-59 years, male
8.9
GTEX-1F5PL-2226-SM-7MKHE
40-49 years, female
8.9
GTEX-15RJ7-0126-SM-6LPJN
40-49 years, male
8.8
GTEX-ZP4G-0326-SM-4YCEF
20-29 years, female
8.8
GTEX-1IDJE-0126-SM-C1YQ6
50-59 years, female
8.8
GTEX-OOBJ-0926-SM-48TDO
60-69 years, male
8.7
GTEX-U3ZN-0126-SM-4DXUM
30-39 years, female
8.7
GTEX-1OFPY-0126-SM-EXOJ3
60-69 years, male
8.6
GTEX-1QCLY-0126-SM-DPRZV
30-39 years, male
8.6
GTEX-146FR-1926-SM-5NQA6
60-69 years, female
8.5
GTEX-Q2AH-0226-SM-48U1I
40-49 years, male
8.5
GTEX-1F5PK-0726-SM-7MGXN
50-59 years, male
8.5
GTEX-XQ8I-1726-SM-4BOQB
50-59 years, male
8.4
GTEX-11LCK-0126-SM-5A5M5
30-39 years, male
8.3
GTEX-11NSD-0426-SM-5N9CR
20-29 years, male
8.3
GTEX-Y8LW-0126-SM-4VBS1
50-59 years, female
8.2
GTEX-P78B-1226-SM-EZ6KP
40-49 years, female
8.2
GTEX-T5JW-0126-SM-4DM6K
20-29 years, female
8.1
GTEX-XGQ4-0126-SM-4AT4H
50-59 years, male
8.1
GTEX-1KANA-1226-SM-DHXKE
20-29 years, male
8.1
GTEX-1R9PM-0126-SM-DPRY6
20-29 years, male
8.1
GTEX-12WSK-0126-SM-5GCO7
40-49 years, female
8.0
GTEX-YEC4-0126-SM-4W21T
40-49 years, male
8.0
GTEX-1AYD5-0226-SM-79ONV
50-59 years, male
7.9
GTEX-1GF9U-0126-SM-AHZ4G
40-49 years, female
7.9
GTEX-12WSJ-0526-SM-5GCOZ
40-49 years, female
7.8
GTEX-13X6H-0726-SM-5Q5BX
50-59 years, female
7.8
GTEX-16XZY-0126-SM-7IGQ9
70-79 years, male
7.8
GTEX-WY7C-0126-SM-4ONCO
50-59 years, male
7.8
GTEX-XXEK-0126-SM-4BRVU
50-59 years, male
7.8
GTEX-14PJ6-0226-SM-6AJ9K
60-69 years, female
7.7
GTEX-XAJ8-0126-SM-47JYG
40-49 years, male
7.7
GTEX-1R9K5-1126-SM-EAZ4G
50-59 years, male
7.7
GTEX-ZDYS-1026-SM-4WKHC
50-59 years, male
7.6
GTEX-ZPIC-0126-SM-DNZZ9
40-49 years, female
7.6
GTEX-131XE-1126-SM-5EGHW
50-59 years, male
7.4
GTEX-1399R-0226-SM-5IJGG
30-39 years, male
7.4
GTEX-146FQ-0626-SM-5LU9U
30-39 years, male
7.4
GTEX-XMK1-0126-SM-4B65F
40-49 years, male
7.4
GTEX-13N11-0126-SM-5KM2Z
50-59 years, female
7.3
GTEX-1PDJ9-0226-SM-DPRYX
20-29 years, male
7.3
GTEX-P4PQ-0926-SM-E9U4D
60-69 years, male
7.2
GTEX-1JKYR-1126-SM-CGQGJ
20-29 years, male
7.1
GTEX-1QCLZ-1026-SM-E6CR1
60-69 years, female
7.1
GTEX-P4QT-0926-SM-EZ6KQ
50-59 years, female
7.1
GTEX-U3ZH-0126-SM-4DXUK
30-39 years, male
7.0
GTEX-O5YT-0926-SM-48TDG
20-29 years, male
6.9
GTEX-1QP66-0126-SM-EAZ3N
50-59 years, male
6.9
GTEX-QV44-0126-SM-CJI1X
50-59 years, male
6.8
GTEX-QV31-0126-SM-447BP
30-39 years, male
6.7
GTEX-QLQW-0126-SM-447BK
30-39 years, male
6.6
GTEX-1CB4F-0226-SM-7EPHS
60-69 years, male
6.3
GTEX-1B8KZ-0226-SM-7EWF6
50-59 years, male
6.2
GTEX-13U4I-1626-SM-5IFFR
40-49 years, female
6.1
GTEX-PX3G-0926-SM-48U12
20-29 years, female
6.1
GTEX-Y3IK-0126-SM-4WWE9
50-59 years, female
5.9
GTEX-1R7EV-0126-SM-EAZ3O
40-49 years, male
5.4
GTEX-18A66-1826-SM-7KFSU
60-69 years, male
5.2
GTEX-1QW4Y-0126-SM-DPRZQ
30-39 years, male
4.8
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SPLEEN - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
The Human Protein Atlas project is funded
