Brain cancer

The upper left dot plot(s) shows the consistency between the cancer type related cell lines and their corresponding TCGA disease cohort based on Spearman correlation and normalized enrichment score (NES). In the lower left is a list of the cell lines ranked according to their similarity to the cancer type. By clicking on a cell line in the dot plot or in the ranked list lollipop plots showing the activity of cancer-related pathways inferred using PROGENy and CytoSig cytokines for that particular cell line will be displayed. For more details about the analysis see Methods summary and information about all cell lines can be found here.

Glioblastoma Multiforme (GBM)

Explore the disease cohort in TCGA

Ranking Cell line Corr NES
1 SNU-626 0.8 1.96
2 YKG-1 0.79 1.92
3 SNU-201 0.81 1.81
4 KNS-81 0.78 1.9
5 U-251MG 0.78 1.83
5 CAS-1 0.79 1.79
7 SNB-75 0.79 1.73
8 KNS-42 0.77 2.05
9 GOS-3 0.78 1.75
10 LN-319 0.77 1.88
11 LN-235 0.78 1.72
12 SNU-466 0.78 1.65
12 DBTRG-05MG 0.79 1.59
14 NCE-G 122 0.77 1.82
15 DK-MG 0.78 1.62
15 NCE-G 28T 0.78 1.66
15 NCE-G 120 0.78 1.7
15 TM-31 0.77 1.75
19 SNU-1105 0.78 1.63
19 SNU-489 0.79 1.52
19 NMC-G1 0.77 1.84
22 LN-340 0.78 1.54
23 NCE-G 130 0.77 1.77
24 KG-1-C 0.77 1.59
25 Hs 683 0.77 1.49
26 CCF-STTG1 0.78 1.44
27 KALS-1 0.77 1.48
28 LN-229 0.76 1.53
29 U-87MG ATCC 0.77 1.51
30 YH-13 0.77 1.46
30 SW1783 0.77 1.39
30 NCE-G 22 0.77 1.49
33 NCE-G 124 0.76 1.56
34 LN-382 0.77 1.39
34 SF268 0.77 1.36
36 GB-1 0.76 1.53
37 GI-1 0.76 1.48
38 LN-443 0.76 1.49
38 U-343MGa 0.77 1.41
40 A-172 0.76 1.41
40 8-MG-BA 0.76 1.41
42 NCE-G 59 0.76 1.42
43 LN-215 0.77 1.24
44 SW1088 0.77 1.15
44 D341 Med 0.72 1.71
46 GMS-10 0.77 1.19
47 U-118MG 0.75 1.5
47 NCE-G 44 0.75 1.49
47 H4 0.76 1.3
50 LN-308 0.74 1.53
51 SF295 0.76 1.25
51 42-MG-BA 0.76 1.37
51 KS-1 [Human glioblas 0.75 1.46
54 KNS-60 0.76 1.39
55 T98G 0.77 1.04
55 M059K 0.75 1.32
57 D283 Med 0.73 1.48
57 SF539 0.77 0.97
59 ONS-76 0.75 1.35
60 SF126 0.76 1.19
61 Daoy 0.75 1.21
62 NCE-G 118 0.76 1.12
63 GAMG 0.76 1.04
63 NCE-G 121 0.76 1.17
65 A-1207 0.75 1.24
65 LN-428 0.75 1.2
67 U-138MG 0.75 1.26
68 NCE-G 140 0.76 1.14
69 U-178MG 0.74 1.27
69 NCE-G 111 0.73 1.27
71 LN-464 0.75 1.22
72 NCE-G 61 0.73 1.2
72 NCE-G 84 0.75 1.08
74 LN-18 0.75 0.84
75 AM-38 0.72 1.19
76 SNU-738 0.75 1.04
77 IOMM-Lee 0.73 1.04
77 CH-157MN 0.74 0.97
79 SF172 0.71 0.57
79 KPL-4 0.7 0.64
CELL LINE DATA
Cell line SNU-626
Patient: Male, 65
Disease subtype: Glioblastoma
Primary/metastasis:
Sample collection site: Central nervous system
Cellosaurus: CVCL_5080
PROGENy
CytoSig

Brain Lower Grade Glioma (LGG)

Explore the disease cohort in TCGA

Ranking Cell line Corr NES
1 SNU-626 0.75 1.85
2 YKG-1 0.75 1.73
2 SNU-201 0.76 1.65
4 KNS-42 0.74 1.88
5 SNB-75 0.75 1.64
6 KNS-81 0.74 1.75
7 CAS-1 0.75 1.63
8 GOS-3 0.74 1.6
9 SNU-466 0.74 1.59
10 LN-319 0.73 1.72
11 U-251MG 0.74 1.57
12 NMC-G1 0.73 1.75
13 NCE-G 122 0.73 1.64
14 NCE-G 120 0.73 1.58
15 TM-31 0.73 1.55
15 KG-1-C 0.73 1.5
17 NCE-G 28T 0.73 1.56
18 D341 Med 0.72 1.74
18 NCE-G 130 0.72 1.62
20 DBTRG-05MG 0.74 1.41
21 SNU-1105 0.73 1.47
21 LN-340 0.73 1.44
23 SNU-489 0.74 1.31
24 DK-MG 0.73 1.44
25 U-87MG ATCC 0.72 1.45
26 LN-235 0.73 1.43
27 LN-229 0.72 1.47
28 CCF-STTG1 0.73 1.39
29 NCE-G 22 0.72 1.39
30 Hs 683 0.72 1.4
31 NCE-G 124 0.72 1.44
32 KALS-1 0.72 1.3
32 LN-443 0.72 1.44
34 SF268 0.73 1.24
34 YH-13 0.72 1.38
36 GB-1 0.71 1.44
37 A-172 0.72 1.37
38 D283 Med 0.71 1.5
39 LN-382 0.72 1.33
40 NCE-G 59 0.72 1.32
41 H4 0.72 1.29
42 U-343MGa 0.72 1.23
42 KS-1 [Human glioblas 0.71 1.44
42 SW1783 0.72 1.21
45 U-118MG 0.7 1.46
46 NCE-G 44 0.71 1.41
47 T98G 0.72 1.2
47 GMS-10 0.72 1.18
49 SW1088 0.72 1.12
50 GI-1 0.71 1.25
51 8-MG-BA 0.71 1.22
52 KNS-60 0.71 1.26
53 SF295 0.71 1.22
53 LN-215 0.72 1.13
55 GAMG 0.71 1.16
56 M059K 0.7 1.27
56 ONS-76 0.71 1.23
58 U-178MG 0.7 1.29
58 LN-464 0.7 1.28
60 NCE-G 121 0.71 1.1
60 SF126 0.71 1.15
62 42-MG-BA 0.71 1.16
62 LN-308 0.7 1.28
64 SF539 0.72 0.96
65 U-138MG 0.7 1.23
66 NCE-G 118 0.71 1.1
67 NCE-G 111 0.69 1.24
68 A-1207 0.7 1.17
69 Daoy 0.71 1.04
70 LN-428 0.71 1.1
71 SNU-738 0.71 1.04
72 NCE-G 140 0.7 1.1
73 AM-38 0.68 1.19
73 NCE-G 61 0.69 1.17
75 LN-18 0.71 0.82
76 NCE-G 84 0.7 1
77 CH-157MN 0.69 1
78 IOMM-Lee 0.68 0.89
79 KPL-4 0.67 0.75
80 SF172 0.66 0.59
CELL LINE DATA
Cell line SNU-626
Patient: Male, 65
Disease subtype: Glioblastoma
Primary/metastasis:
Sample collection site: Central nervous system
Cellosaurus: CVCL_5080
PROGENy
CytoSig

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