Single cell type expression cluster

e.g. Metabolic proteins, Localized to mitochondria, Genes tissue enriched in brain (RNA)

Field

Cluster

Pathway

IDⁱ The ID of each cluster.	Main specificityⁱ The annotated specificity of the cluster. This annotation aims to reflect which type of tissues or cell types the genes of the cluster show elevated expression in.	Main functionⁱ The annotated function of the cluster, based on an overrepresentation of genes associated with the annotated function.	# Genesⁱ Number of genes in the cluster.	Annotation reliabilityⁱ The annotation reliability is manually set for all clusters and indicates the level of reliability of the annotated specificity and function.
1	Erythroid cells	Oxygen transport	138	High
2	Skeletal myocytes	Muscle contraction	133	High
3	Basal prostatic cells	Lipid metabolism	162	Medium
4	Extravillous trophoblasts	Unknown function	182	Medium
5	Enterocytes	Absorption	330	Medium
6	Ovarian stromal cells	Transcription	188	Medium
7	T-cells	T-cell receptor	246	Medium
8	Neurons	Neuronal signaling	265	Medium
9	Endometrial stromal cells	Transcription	129	Medium
10	Muller glia cells	Visual perception	166	High
11	Late spermatids	Unknown function	430	Medium
12	Squamous epithelial cells	Keratinization	309	High
13	Spermatids	Transcription	116	High
14	Langerhans cells	Innate immune response	131	Medium
15	Non-specific	Mixed function	295	Low
16	Intestinal goblet cells	Mucin production	268	Medium
17	Breast glandular cells	Lactation	115	Medium
18	Early spermatids	Unknown function	283	High
19	NK-cells	Adaptive immune response	266	Medium
20	Enteroendocrine cells	Hormone signaling	85	High
21	Early spermatids	Spermatogenesis	337	Medium
22	Proximal enterocytes	Digestion	255	High
23	Plasma cells	Humoral immune response	80	High
24	Cytotrophoblasts	Mitochondria	235	Medium
25	Bipolar cells	Visual perception	152	Medium
26	Schwann cells & Melanocytes	Mixed function	63	High
27	Syncytiotrophoblasts	Pregnancy	142	Medium
28	Dendritic cells	Antigen presentation	245	Medium
29	Monocytes	Innate immune response	447	Medium
30	Granulocytes	Unknown function	76	Medium
31	Spermatocytes	Spermatogenesis	240	High
32	Smooth muscle cells	Muscle contraction	236	Medium
33	Non-specific	DNA binding	138	Medium
34	Neurons	Neuronal signaling	518	Medium
35	Respiratory epithelial cells	Unknown function	196	Low
36	Late spermatids	Unknown function	427	High
37	Glandular & Luminal cells	Unknown function	334	Low
38	Proximal tubular cells	Transmembrane transport	131	High
39	Non-specific	Basic cellular processes	835	Medium
40	Prostatic glandular cells	Transcription	76	High
41	Adipocytes & Endothelial cells	Mixed function	325	Medium
42	Ciliated cells	Cilium assembly	429	High
43	Hepatocytes	Metabolism	200	High
44	Oocytes	Unknown function	133	High
45	Non-specific	Mixed function	349	Medium
46	Gastric mucus-secreting cells	Digestion	41	Medium
47	Astrocytes	Unknown function	196	High
48	Smooth muscle cells	Signal transduction	187	Medium
49	Non-specific	Transcription	378	Medium
50	Connective tissue cells	ECM organization	176	Medium
51	Oligodendrocytes	Unknown function	302	Medium
52	Non-specific	Cell proliferation	248	High
53	Fibroblasts	ECM organization	305	High
54	Lymphatic endothelial cells	Lymph vessel development	108	Medium
55	Non-specific	Transcription	709	High
56	Proximal tubular cells	Amino acid metabolism	204	Medium
57	Platelets	Hemostasis	173	High
58	Macrophages	Innate immune response	420	Medium
59	Suprabasal keratinocytes	Cornification	186	High
60	Pancreatic exocrine cells	Proteolysis	47	Medium
61	Plasma cells	Immunoglobulins & histones	169	High
62	Hepatocytes	Metabolism	159	High
63	Late spermatids	Spermatogenesis	383	Medium
64	Non-specific	Ribosome	168	High
65	Neurons	Synaptic function	250	High
66	Photoreceptor cells	Visual perception	340	High
67	Spermatogonia	Spermatogenesis	123	High
68	Cardiomyocytes	Muscle contraction	262	High
69	Neurons	Neuronal signaling	331	High
70	Spermatocytes & Spermatids	Spermatid development	376	High
71	Horizontal & Bipolar cells	Neuronal signaling	205	High
72	Alveolar cells	Lung function	121	High
73	B-cells	B-cell function	195	High
74	Neutrophils	Degranulation	174	High
75	Serous glandular cells	Salivary secretion	145	Medium
76	Oligodendrocyte precursor	Unknown function	210	Medium
77	Plasma cells	Protein processing	324	Medium
78	NK-cells & T-cells	Immune system & Transcription	392	Medium
79	Spermatocytes & Spermatogonia	Spermatogenesis	176	High
80	Non-specific	Transcription	184	High

The interactive UMAP plot displays the 80 gene clusters resulting from Louvain clustering of gene expression across all single cell types. General information about the different clusters regarding annotation and number of included genes is shown upon mouse-over, while clicking on a specific cluster in the table will highlight the selected cluster in the plot and display the general information together with a heatmap of the RNA expression across all single cell types for corresponding genes and a Gene Ontology treemap showing the enrichment of GO-terms in the cluster, where applicable.

Adipocytes
Blood & immune cells
Endocrine cells
Endothelial cells
Germ cells
Glandular epithelial cells
Glial cells
Mesenchymal cells
Muscle cells
Neuronal cells
Specialized epithelial cells
Squamous epithelial cells
Trophoblast cells
Other
Non-Specific