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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Medium
Hepatocytes:
High
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
16.7
nTPM
HPA:
13.9
nTPM
GTEx:
16.7
nTPM
FANTOM5:
29.6
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA031226
Cholangiocytes
Medium
Hepatocytes
High
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPM
13.9
Female, age 60
Liver sample 21 nTPM: 11.4
Male, age 54
Liver sample 23 nTPM: 12.7
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 11.2
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 14.1
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 19.4
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 16
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 13
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 10.6
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 17.7
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 13.2
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Average nTPM
16.7
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 16.7
Samples: 226
Max nTPM: 49.5
Min nTPM: 4.4
Std nTPM: 7.7
Median nTPM: 15.6
GTEX-18465-1626-SM-7LG6N
50-59 years, male
49.5
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
43.2
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
40.6
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
38.6
GTEX-YECK-1926-SM-4W21H
60-69 years, male
38.4
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
36.8
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
36.5
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
35.8
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
32.9
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
32.9
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
32.7
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
31.5
GTEX-14JG1-1626-SM-664NH
40-49 years, male
29.0
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
29.0
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
28.9
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
28.8
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
28.6
GTEX-QESD-2026-SM-447BI
20-29 years, male
28.6
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
28.6
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
28.4
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
28.4
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
28.3
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
27.9
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
26.6
GTEX-144GL-1426-SM-79OMA
50-59 years, male
26.6
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
25.9
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
25.6
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
25.5
GTEX-11ZUS-2526-SM-59872
30-39 years, male
25.2
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
25.1
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
24.9
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
24.7
GTEX-18A7A-1526-SM-72D69
50-59 years, female
24.4
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
24.4
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
24.2
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
24.0
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
24.0
GTEX-13112-1426-SM-5EGH8
50-59 years, male
23.7
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
23.4
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
23.2
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
23.1
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
23.0
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
22.9
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
22.6
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
22.3
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
22.3
GTEX-17HHE-0126-SM-79398
50-59 years, male
22.1
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
22.1
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
22.0
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
21.6
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
21.5
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
21.4
GTEX-1399T-0826-SM-5IFES
60-69 years, male
21.2
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
21.2
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
21.1
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
21.1
GTEX-11GSP-0626-SM-5986T
60-69 years, female
20.8
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
20.8
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
20.7
GTEX-RN64-1826-SM-48FDV
50-59 years, male
20.7
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
20.7
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
20.1
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
20.0
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
19.8
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
19.7
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
19.6
GTEX-14E7W-1526-SM-6871X
70-79 years, male
19.5
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
19.5
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
19.2
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
19.1
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
19.1
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
19.0
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
18.9
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
18.7
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
18.4
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
18.2
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
18.1
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
18.1
GTEX-1B933-1226-SM-731DW
50-59 years, female
18.1
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
18.1
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
18.1
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
18.0
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
17.8
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
17.7
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
17.5
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
17.5
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
17.4
GTEX-RU72-1426-SM-46MUF
50-59 years, female
17.3
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
17.2
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
17.2
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
17.1
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
17.1
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
16.6
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
16.6
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
16.6
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
16.5
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
16.4
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
16.3
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
16.3
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
16.1
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
16.1
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
16.0
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
16.0
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
15.9
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
15.9
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
15.9
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
15.9
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
15.9
GTEX-Q734-0326-SM-48U15
40-49 years, female
15.8
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
15.8
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
15.7
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
15.7
GTEX-12696-0826-SM-5EGGE
60-69 years, male
15.6
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
15.6
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
15.6
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
15.5
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
15.3
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
15.2
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
15.2
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
15.1
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
15.1
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
15.0
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
14.9
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
14.9
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
14.9
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
14.7
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
14.6
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
14.5
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
14.4
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
14.3
GTEX-13113-1326-SM-5GCOI
60-69 years, female
13.9
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
13.8
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
13.8
GTEX-R53T-0326-SM-48FEC
50-59 years, female
13.7
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
13.7
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
13.4
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
13.3
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
13.2
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
13.2
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
13.2
GTEX-S33H-1626-SM-4AD68
30-39 years, male
13.2
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
13.2
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
13.1
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
13.0
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
12.7
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
12.7
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
12.6
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
12.5
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
12.5
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
12.4
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
12.2
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
12.1
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
12.1
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
12.1
GTEX-18A66-2026-SM-7189C
60-69 years, male
12.0
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
12.0
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
11.9
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
11.8
GTEX-17F96-1226-SM-79OK2
70-79 years, male
11.6
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
11.6
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
11.6
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
11.5
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
11.5
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
11.3
GTEX-14PHX-0526-SM-664NW
50-59 years, male
11.1
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
11.1
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
11.0
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
11.0
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
10.8
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
10.8
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
10.7
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
10.7
GTEX-REY6-1226-SM-48FDR
60-69 years, male
10.5
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
10.5
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
10.5
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
10.4
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
10.2
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
10.2
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
10.2
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
10.1
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
10.0
GTEX-P78B-1326-SM-3P611
40-49 years, female
10.0
GTEX-QEL4-1226-SM-447A4
50-59 years, male
10.0
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
9.9
GTEX-1B932-1426-SM-793AN
40-49 years, female
9.8
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
9.7
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
9.6
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
9.5
GTEX-14PJO-1726-SM-68719
60-69 years, male
9.4
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
9.4
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
9.3
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
9.3
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
9.3
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
9.2
GTEX-X261-1726-SM-4PQYT
50-59 years, male
9.2
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
9.1
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
8.9
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
8.9
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
8.9
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
8.9
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
8.8
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
8.8
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
8.8
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
8.6
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
8.4
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
8.4
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
8.1
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
8.0
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
8.0
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
7.7
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
7.3
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
7.3
GTEX-O5YV-0726-SM-EV798
60-69 years, female
7.3
GTEX-S32W-1926-SM-4AD63
50-59 years, female
7.2
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
7.1
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
7.0
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
6.9
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
6.7
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
6.4
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
6.3
GTEX-14XAO-0226-SM-68728
60-69 years, female
5.9
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
5.8
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
5.3
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
5.0
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
5.0
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
4.4
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
The Human Protein Atlas project is funded
