CEREBRAL CORTEX - Expression summary
Protein expression
Cerebral cortexi
h
m
l
n
Endothelial cells: Medium
Glial cells: Not detected
Neuronal cells: Not detected
Neuropil: Low
RNA expressioni
Consensus:35.0 nTPM
HPA:35.0 nTPM
HPA Brain:31.8 nTPM
HPA PFC Brain:43.1 nTPM
GTEx:21.9 nTPM
FANTOM5:64.0 Scaled Tags Per Million
Pig:10.5 nTPM
Mouse:45.4 nTPM
Allen mouse:2.5 Expression energy

CEREBRAL CORTEX - Antibody stainingi
Antibody HPA014141
Endothelial cells Medium
Glial cells Not detected
Neuronal cells Not detected
Neuropil Low



CEREBRAL CORTEX - HPA RNA-seqi
Average nTPM 35.0
N/A
Male, age 5
Cerebral cortex sample 48
nTPM: 34.6
overview
Female, age 40
Cerebral cortex sample 105
nTPM: 42.6
Cell types%
Neuronal cells:
35

Glial cells and endothelial cells:
65
overview
Male, age 70
Cerebral cortex sample 106
nTPM: 27.7
Cell types%
Neuronal cells:
35

Glial cells and endothelial cells:
65

CEREBRAL CORTEX - HPA Brain RNA-seq
Max nTPM 31.8
Sample id Sample description nTPM
Angular gyrus
nTPM: 22.8
2103 Male, age 75, left hemisphere 37.0
1790 Male, age 76, right hemisphere 26.2
2722 Male, age 61, left hemisphere 23.4
2265 Female, age 91, left hemisphere 21.3
1866 Male, age 76, both hemispheres 19.8
2260 Female, age 72, left hemisphere 18.9
2221 Female, age 67, right hemisphere 18.0
2602 Female, age 94, right hemisphere 18.0
Anterior cingulate cortex, supragenual-dorsal
nTPM: 19.6
1896 Female, age 85, right hemisphere 25.7
2547 Male, age 74, left hemisphere 20.0
2472 Male, age 75, left hemisphere 19.5
2342 Female, age 94, right hemisphere 17.0
2478 Female, age 67, right hemisphere 15.7
Anterior cingulate cortex, supragenual-ventral
nTPM: 23.8
1950 Female, age 85, right hemisphere 31.5
2479 Female, age 67, right hemisphere 24.3
1761 Male, age 74, left hemisphere 23.8
1755 Female, age 94, right hemisphere 21.3
2538 Male, age 75, left hemisphere 18.3
Anterior insular cortex, dorsal
nTPM: 18.2
2001 Male, age 76, right hemisphere 18.6
2235 Female, age 91, right hemisphere 18.5
2670 Male, age 75, left hemisphere 18.5
2506 Female, age 94, right hemisphere 17.2
Anterior insular cortex, ventral
nTPM: 19.3
2596 Male, age 75, left hemisphere 29.5
2262 Female, age 67, right hemisphere 18.8
1925 Female, age 91, left hemisphere 17.6
1852 Male, age 76, left hemisphere 16.8
2757 Male, age 61, right hemisphere 16.7
2507 Female, age 94, left hemisphere 16.6
Area parastriata, inferior
nTPM: 30.9
2509 Female, age 94, left hemisphere 56.9
2234 Male, age 75, left hemisphere 45.3
1789 Male, age 76, right hemisphere 26.3
2421 Female, age 91, left hemisphere 25.9
2268 Male, age 61, right hemisphere 22.1
1758 Female, age 72, right hemisphere 21.7
1760 Female, age 67, left hemisphere 18.0
Area parastriata, parietal
nTPM: 31.8
2420 Male, age 75, left hemisphere 49.4
2233 Male, age 61, right hemisphere 42.5
2680 Female, age 94, right hemisphere 23.4
2236 Female, age 91, left hemisphere 22.2
1785 Male, age 76, right hemisphere 21.6
Area parastriata, superior
nTPM: 30.4
2435 Male, age 61, left hemisphere 41.4
2604 Female, age 94, right hemisphere 41.1
2419 Male, age 75, right hemisphere 39.1
2684 Female, age 67, left hemisphere 27.3
1773 Female, age 91, left hemisphere 19.3
2881 Male, age 76, left hemisphere 14.2
Area parastriata, temporal
nTPM: 23.6
2424 Female, age 67, left hemisphere 31.2
2267 Male, age 61, right hemisphere 25.0
2681 Female, age 94, right hemisphere 24.5
2471 Male, age 75, left hemisphere 19.1
1804 Male, age 76, right hemisphere 17.9
Area striata
nTPM: 29.2
1884 Male, age 76, left hemisphere 55.6
2002 Female, age 91, right hemisphere 32.3
2417 Male, age 61, right hemisphere 25.8
2679 Female, age 94, right hemisphere 21.5
1753 Female, age 72, right hemisphere 20.8
2427 Female, age 91, left hemisphere 18.9
Claustrum
nTPM: 22.7
2392 Female, age 94, both hemispheres 29.0
1956 Male, age 74, unknown 28.9
2292 Female, age 85, both hemispheres 26.8
2196 Female, age 79, unknown 26.0
2198 Male, age 80, both hemispheres 20.9
2491 Male, age 75, both hemispheres 20.3
2568 Male, age 61, both hemispheres 18.0
2284 Female, age 91, both hemispheres 17.3
2645 Female, age 72, unknown 16.9
Frontal eye field
nTPM: 18.6
2147 Male, age 61, left hemisphere 27.9
2761 Female, age 94, left hemisphere 17.0
2441 Male, age 75, left hemisphere 15.9
2543 Male, age 74, left hemisphere 13.6
Frontal operculum
nTPM: 29.0
2030 Male, age 61, right hemisphere 43.1
2348 Male, age 75, left hemisphere 25.3
2781 Female, age 85, right hemisphere 18.5
Fusiform gyrus
nTPM: 17.7
2433 Female, age 72, left hemisphere 27.1
2431 Male, age 75, right hemisphere 20.4
2074 Female, age 91, left hemisphere 18.2
1807 Male, age 76, left hemisphere 17.2
2617 Female, age 94, left hemisphere 14.4
2112 Male, age 80, both hemispheres 13.4
2784 Female, age 85, left hemisphere 13.4
Inferior frontal gyrus, opercular
nTPM: 19.8
2874 Female, age 85, right hemisphere 30.4
2866 Male, age 61, right hemisphere 21.7
2875 Female, age 67, left hemisphere 20.9
2868 Male, age 75, right hemisphere 20.7
2865 Male, age 61, left hemisphere 19.4
2873 Female, age 85, left hemisphere 17.8
2871 Female, age 94, left hemisphere 17.4
2869 Male, age 74, left hemisphere 17.1
2867 Male, age 75, left hemisphere 16.8
2872 Female, age 94, right hemisphere 15.3
Inferior parietal lobule
nTPM: 18.4
2418 Male, age 75, left hemisphere 21.2
2606 Female, age 67, right hemisphere 20.5
2599 Female, age 94, left hemisphere 18.4
2876 Male, age 76, right hemisphere 13.5
Inferior temporal gyrus
nTPM: 18.9
1808 Male, age 76, left hemisphere 21.5
2430 Male, age 75, right hemisphere 20.6
2689 Female, age 94, right hemisphere 20.5
1970 Female, age 85, right hemisphere 20.0
1965 Female, age 91, left hemisphere 16.2
1880 Male, age 80, right hemisphere 14.7
Intraparietal deep sulcus
nTPM: 26.2
2600 Female, age 94, right hemisphere 34.1
2102 Female, age 91, left hemisphere 33.9
2607 Female, age 67, right hemisphere 27.1
2669 Male, age 75, left hemisphere 25.8
2798 Male, age 76, left hemisphere 18.6
2230 Male, age 61, right hemisphere 17.8
Lingual gyrus
nTPM: 17.0
2073 Female, age 85, left hemisphere 23.3
1893 Male, age 76, left hemisphere 20.2
2688 Male, age 75, right hemisphere 17.3
2838 Male, age 80, right hemisphere 12.3
2618 Female, age 94, left hemisphere 11.7
Middle cingulate cortex
nTPM: 22.2
2640 Female, age 94, right hemisphere 28.6
2633 Male, age 74, left hemisphere 23.3
2539 Male, age 75, left hemisphere 20.9
2028 Female, age 85, left hemisphere 20.7
2357 Female, age 67, right hemisphere 17.7
Middle temporal gyrus
nTPM: 18.2
1819 Male, age 80, right hemisphere 21.6
1799 Male, age 76, left hemisphere 21.3
2616 Female, age 94, left hemisphere 17.6
2611 Male, age 75, right hemisphere 16.1
2034 Female, age 91, right hemisphere 14.6
Occipital cortex
nTPM: 20.7
2677 Female, age 67, right hemisphere 30.0
2470 Male, age 75, right hemisphere 21.2
2426 Male, age 75, midline 20.6
1842 Male, age 76, right hemisphere 17.2
2608 Female, age 67, both hemispheres 14.5
Olfactory area
nTPM: 15.0
2440 Male, age 75, left hemisphere 20.5
2542 Male, age 74, left hemisphere 18.2
1805 Female, age 85, right hemisphere 16.8
2352 Female, age 94, right hemisphere 13.4
2756 Female, age 67, right hemisphere 10.8
2222 Female, age 67, right hemisphere 10.4
Olfactory tubercle
nTPM: 15.2
1846 Male, age 80, right hemisphere 17.5
2856 Male, age 75, right hemisphere 16.9
2487 Female, age 94, left hemisphere 13.9
1998 Female, age 91, both hemispheres 12.7
Orbitofrontal gyrus, anterior
nTPM: 23.4
2864 Female, age 67, left hemisphere 29.3
2862 Female, age 85, left hemisphere 22.7
2863 Female, age 85, right hemisphere 18.3
Paracentral lobule, anterior
nTPM: 22.4
2340 Female, age 67, right hemisphere 27.6
1776 Female, age 85, right hemisphere 25.0
1754 Male, age 75, left hemisphere 22.8
1926 Male, age 61, left hemisphere 22.2
2638 Female, age 94, right hemisphere 21.1
2474 Male, age 74, left hemisphere 15.9
Paracentral lobule, posterior
nTPM: 25.4
2551 Female, age 94, right hemisphere 34.4
1764 Male, age 74, right hemisphere 29.4
1775 Female, age 85, right hemisphere 22.2
2446 Male, age 75, left hemisphere 20.7
2345 Male, age 61, left hemisphere 20.4
Parietal operculum
nTPM: 17.5
2356 Female, age 67, right hemisphere 19.6
2719 Male, age 75, left hemisphere 18.7
1763 Male, age 74, left hemisphere 17.4
2552 Female, age 94, right hemisphere 14.2
Parieto-insular cortex
nTPM: 17.5
1976 Female, age 91, right hemisphere 20.3
2232 Male, age 61, right hemisphere 18.0
2508 Female, age 94, right hemisphere 16.8
2671 Male, age 75, left hemisphere 16.6
2831 Male, age 76, right hemisphere 15.9
Parieto-occipital transitional area
nTPM: 20.6
1784 Male, age 76, right hemisphere 22.1
2674 Female, age 94, right hemisphere 21.8
2468 Male, age 75, left hemisphere 20.8
2683 Female, age 67, left hemisphere 19.3
2270 Male, age 61, right hemisphere 19.2
Piriform cortex
nTPM: 31.0
2347 Male, age 75, right hemisphere 34.4
2153 Female, age 85, left hemisphere 27.7
Postcentral gyrus
nTPM: 16.5
2533 Male, age 75, right hemisphere 16.5
Postcentral gyrus, dorsal
nTPM: 28.2
2339 Female, age 67, right hemisphere 49.4
2477 Female, age 94, right hemisphere 38.6
1836 Female, age 85, right hemisphere 26.2
2350 Male, age 75, left hemisphere 20.2
2151 Male, age 61, left hemisphere 20.0
2544 Male, age 74, left hemisphere 14.9
Postcentral gyrus, middle
nTPM: 21.8
2248 Male, age 61, left hemisphere 28.7
1897 Female, age 85, right hemisphere 25.3
2146 Female, age 67, right hemisphere 20.4
2545 Male, age 74, left hemisphere 19.2
2444 Male, age 75, left hemisphere 15.5
Postcentral gyrus, ventral
nTPM: 26.5
2024 Female, age 85, right hemisphere 33.9
2836 Female, age 94, right hemisphere 25.2
2445 Male, age 75, left hemisphere 20.4
Posterior cingulate cortex
nTPM: 23.4
2473 Male, age 75, left hemisphere 26.0
1759 Male, age 74, right hemisphere 25.9
2553 Female, age 94, right hemisphere 18.2
Posterior cingulate cortex, dorsal
nTPM: 24.4
2641 Female, age 94, right hemisphere 30.4
2343 Male, age 61, left hemisphere 29.6
2556 Female, age 67, right hemisphere 29.3
2076 Female, age 85, right hemisphere 21.2
2634 Male, age 74, left hemisphere 21.0
2540 Male, age 75, right hemisphere 14.9
Posterior cingulate cortex, ventral
nTPM: 22.8
2448 Female, age 67, right hemisphere 32.9
2541 Male, age 75, right hemisphere 29.9
1994 Female, age 85, right hemisphere 19.4
2635 Male, age 74, left hemisphere 19.3
1762 Female, age 94, right hemisphere 19.1
2346 Male, age 61, left hemisphere 16.1
Posterior insular cortex
nTPM: 14.4
2597 Male, age 75, left hemisphere 16.1
1823 Male, age 76, right hemisphere 15.9
2511 Female, age 67, right hemisphere 15.1
2231 Male, age 61, left hemisphere 14.9
2832 Female, age 91, right hemisphere 13.3
2603 Female, age 94, left hemisphere 11.2
Precentral gyrus
nTPM: 13.5
2557 Male, age 75, right hemisphere 13.5
Precentral gyrus, dorsal
nTPM: 30.7
1756 Male, age 74, left hemisphere 37.6
2476 Female, age 94, right hemisphere 37.4
2442 Male, age 75, left hemisphere 27.5
2354 Female, age 67, right hemisphere 20.3
Precentral gyrus, middle
nTPM: 27.6
2475 Male, age 74, right hemisphere 40.5
2443 Male, age 75, left hemisphere 32.7
1969 Female, age 67, right hemisphere 23.5
1909 Male, age 61, left hemisphere 22.3
2549 Female, age 94, right hemisphere 18.8
Precentral gyrus, ventral
nTPM: 26.5
2662 Female, age 67, right hemisphere 50.6
2630 Male, age 75, left hemisphere 18.9
2678 Male, age 74, left hemisphere 18.3
2550 Female, age 94, right hemisphere 17.9
Precuneus
nTPM: 25.3
2467 Male, age 75, right hemisphere 38.3
2673 Female, age 94, right hemisphere 25.2
2510 Female, age 67, right hemisphere 25.1
1782 Male, age 76, right hemisphere 24.1
2594 Male, age 61, left hemisphere 19.9
1780 Female, age 91, right hemisphere 19.3
Premotor cortex, dorsal
nTPM: 24.7
2631 Male, age 74, left hemisphere 29.8
2554 Female, age 67, right hemisphere 28.0
1878 Female, age 85, right hemisphere 22.3
2027 Male, age 61, left hemisphere 22.1
2536 Male, age 75, left hemisphere 21.2
Premotor cortex, ventral
nTPM: 22.2
1777 Female, age 67, left hemisphere 27.8
2349 Male, age 75, left hemisphere 25.9
1881 Female, age 85, right hemisphere 24.8
1757 Male, age 74, left hemisphere 19.3
2637 Female, age 94, right hemisphere 19.0
1779 Male, age 61, left hemisphere 16.1
Retrosplenial cortex
nTPM: 21.9
1914 Male, age 76, right hemisphere 27.6
2675 Female, age 94, left hemisphere 23.1
1951 Male, age 61, right hemisphere 15.0
Subcentral gyrus, S2
nTPM: 19.3
2072 Male, age 61, left hemisphere 22.5
2351 Male, age 75, left hemisphere 20.6
2762 Male, age 74, left hemisphere 20.6
1964 Female, age 85, right hemisphere 19.5
2839 Female, age 94, right hemisphere 17.6
2555 Female, age 67, right hemisphere 15.3
Superior parietal lobule
nTPM: 25.9
1992 Female, age 91, right hemisphere 35.0
1800 Male, age 76, right hemisphere 30.6
2605 Female, age 67, right hemisphere 22.4
2672 Female, age 94, right hemisphere 21.5
2229 Male, age 61, right hemisphere 19.8
Superior temporal gyrus
nTPM: 16.6
1844 Female, age 91, left hemisphere 18.5
2025 Male, age 80, right hemisphere 17.8
2687 Male, age 75, right hemisphere 17.8
1843 Male, age 76, left hemisphere 16.4
2615 Female, age 94, left hemisphere 12.5
Supplementary motor cortex
nTPM: 21.6
2632 Male, age 74, left hemisphere 33.2
1993 Male, age 61, left hemisphere 20.7
2537 Male, age 75, left hemisphere 18.0
2548 Female, age 94, right hemisphere 14.3
Supramarginal gyrus
nTPM: 18.3
2601 Female, age 94, left hemisphere 21.6
1991 Female, age 91, right hemisphere 19.0
2415 Male, age 61, left hemisphere 18.3
2513 Female, age 72, left hemisphere 17.3
1798 Male, age 76, right hemisphere 15.2
Temporal pole
nTPM: 18.7
1826 Male, age 76, right hemisphere 25.5
1853 Female, age 85, right hemisphere 21.7
2518 Male, age 75, right hemisphere 20.3
2612 Female, age 94, left hemisphere 13.0
1832 Female, age 91, left hemisphere 12.8
Temporo-insular cortex, parainsular gyrus
nTPM: 20.7
2512 Female, age 67, right hemisphere 32.8
2416 Male, age 61, right hemisphere 28.0
2264 Female, age 91, right hemisphere 21.4
1802 Male, age 76, left hemisphere 15.6
2598 Male, age 75, left hemisphere 14.8
2676 Female, age 94, right hemisphere 11.5
Temporo-occipital transitional zone
nTPM: 20.8
1900 Male, age 76, left hemisphere 26.0
2251 Female, age 85, right hemisphere 18.9
1793 Male, age 80, right hemisphere 17.3
Transversal temporal gyrus, anterior
nTPM: 18.2
2522 Female, age 94, left hemisphere 22.6
1809 Male, age 76, right hemisphere 20.3
1888 Female, age 91, left hemisphere 17.6
1910 Male, age 80, right hemisphere 15.4
2610 Male, age 75, right hemisphere 15.1
Transversal temporal gyrus, posterior
nTPM: 20.7
2520 Male, age 75, right hemisphere 30.5
1922 Male, age 76, left hemisphere 19.8
2614 Female, age 94, left hemisphere 19.1
1967 Female, age 91, right hemisphere 17.5
2833 Male, age 80, right hemisphere 16.4

CEREBRAL CORTEX - HPA PFC Brain RNA-seq
Max nTPM 43.1
Sample id Sample description nTPM
Anterior cingulate gyrus, pregenual-dorsal
nTPM: 21.1
1513 Male, age 74, left hemisphere 34.3
1518 Female, age 67, right hemisphere 27.6
1514 Male, age 74, right hemisphere 27.0
1512 Male, age 75, left hemisphere 23.1
1517 Female, age 67, left hemisphere 20.8
1515 Female, age 94, right hemisphere 17.1
1510 Male, age 61, left hemisphere 15.7
1511 Male, age 61, right hemisphere 12.1
1516 Female, age 85, left hemisphere 12.1
Anterior cingulate gyrus, pregenual-ventral
nTPM: 16.3
1522 Male, age 74, right hemisphere 20.7
1520 Male, age 75, right hemisphere 19.3
1523 Female, age 67, left hemisphere 17.6
1521 Male, age 74, left hemisphere 15.2
1519 Male, age 61, left hemisphere 8.9
Anterior cingulate gyrus, subgenual
nTPM: 20.1
1530 Female, age 67, right hemisphere 35.8
1526 Male, age 75, right hemisphere 22.1
1528 Male, age 74, right hemisphere 21.5
1525 Male, age 75, left hemisphere 19.0
1527 Male, age 74, left hemisphere 17.5
1524 Male, age 61, left hemisphere 16.9
1529 Female, age 85, left hemisphere 7.8
Dorsolateral prefrontal cortex
nTPM: 22.6
1446 Male, age 74, right hemisphere 30.4
1449 Female, age 85, right hemisphere 29.0
1447 Female, age 94, left hemisphere 24.4
1448 Female, age 94, right hemisphere 20.4
1444 Male, age 75, left hemisphere 19.9
1445 Male, age 75, right hemisphere 19.3
1450 Female, age 67, right hemisphere 14.8
Dorsomedial prefrontal cortex
nTPM: 18.1
1443 Female, age 67, right hemisphere 32.6
1441 Male, age 75, left hemisphere 21.7
1439 Male, age 61, left hemisphere 16.2
1440 Male, age 61, right hemisphere 12.2
1442 Male, age 75, right hemisphere 8.0
Frontal cortex
nTPM: 43.1
1576 Male, age 74, left hemisphere 76.8
1582 Female, age 67, left hemisphere 75.2
1583 Female, age 67, right hemisphere 56.7
1572 Male, age 61, left hemisphere 49.4
1577 Male, age 74, right hemisphere 48.2
1574 Male, age 75, left hemisphere 35.9
1581 Female, age 85, right hemisphere 35.1
1579 Female, age 94, right hemisphere 33.8
1578 Female, age 94, left hemisphere 31.0
1580 Female, age 85, left hemisphere 28.3
1575 Male, age 75, right hemisphere 26.0
1573 Male, age 61, right hemisphere 20.7
Frontomarginal cortex
nTPM: 22.1
1473 Female, age 67, right hemisphere 38.4
1468 Male, age 74, left hemisphere 31.9
1472 Female, age 67, left hemisphere 23.5
1471 Female, age 85, left hemisphere 23.4
1467 Male, age 75, right hemisphere 22.0
1469 Female, age 94, left hemisphere 21.6
1470 Female, age 94, right hemisphere 17.4
1466 Male, age 61, right hemisphere 11.8
1465 Male, age 61, left hemisphere 8.8
Frontopolar cortex
nTPM: 24.4
1464 Female, age 67, right hemisphere 64.3
1463 Female, age 67, left hemisphere 23.9
1460 Male, age 75, left hemisphere 22.7
1461 Male, age 75, right hemisphere 19.2
1462 Female, age 94, left hemisphere 16.4
1459 Male, age 61, right hemisphere 13.5
1458 Male, age 61, left hemisphere 10.9
Gyrus rectus
nTPM: 22.3
1481 Female, age 67, left hemisphere 51.7
1476 Male, age 75, left hemisphere 25.6
1477 Male, age 75, right hemisphere 21.0
1474 Male, age 61, left hemisphere 17.7
1480 Female, age 85, left hemisphere 17.7
1479 Female, age 94, right hemisphere 16.3
1478 Female, age 94, left hemisphere 15.8
1475 Male, age 61, right hemisphere 12.6
Inferior frontal gyrus, orbital
nTPM: 18.9
1509 Female, age 67, right hemisphere 30.8
1505 Male, age 74, right hemisphere 26.8
1504 Male, age 74, left hemisphere 22.8
1503 Male, age 75, right hemisphere 19.9
1502 Male, age 75, left hemisphere 19.5
1506 Female, age 94, left hemisphere 15.3
1501 Male, age 61, right hemisphere 15.1
1507 Female, age 85, left hemisphere 13.5
1500 Male, age 61, left hemisphere 12.5
1508 Female, age 85, right hemisphere 12.4
Inferior frontal gyrus, triangular
nTPM: 18.4
1547 Female, age 85, left hemisphere 26.7
1544 Male, age 75, right hemisphere 24.1
1549 Female, age 67, left hemisphere 20.2
1548 Female, age 85, right hemisphere 19.3
1545 Male, age 74, right hemisphere 17.8
1546 Female, age 94, right hemisphere 14.9
1543 Male, age 61, right hemisphere 12.7
1542 Male, age 61, left hemisphere 11.7
Orbitofrontal gyrus, lateral
nTPM: 18.7
1499 Female, age 67, right hemisphere 34.1
1494 Male, age 75, left hemisphere 19.7
1495 Female, age 94, left hemisphere 18.5
1496 Female, age 94, right hemisphere 18.5
1497 Female, age 85, left hemisphere 15.0
1498 Female, age 85, right hemisphere 14.1
1493 Male, age 61, right hemisphere 11.0
Orbitofrontal gyrus, medial
nTPM: 41.3
1485 Male, age 74, left hemisphere 64.6
1491 Female, age 67, left hemisphere 61.8
1486 Male, age 74, right hemisphere 60.0
1492 Female, age 67, right hemisphere 50.4
1484 Male, age 75, right hemisphere 41.5
1482 Male, age 61, left hemisphere 36.1
1483 Male, age 75, left hemisphere 34.0
1490 Female, age 85, right hemisphere 29.5
1487 Female, age 94, left hemisphere 28.6
1489 Female, age 85, left hemisphere 26.7
1488 Female, age 94, right hemisphere 21.4
Orbitofrontal gyrus, posterior
nTPM: 19.1
1541 Female, age 67, right hemisphere 33.3
1534 Male, age 75, right hemisphere 25.1
1535 Male, age 74, left hemisphere 24.7
1540 Female, age 67, left hemisphere 23.2
1539 Female, age 85, right hemisphere 22.8
1533 Male, age 75, left hemisphere 18.3
1531 Male, age 61, left hemisphere 15.0
1537 Female, age 94, right hemisphere 12.2
1538 Female, age 85, left hemisphere 12.2
1532 Male, age 61, right hemisphere 12.0
1536 Female, age 94, left hemisphere 11.2
Subcallosal gyrus
nTPM: 28.3
1560 Female, age 67, left hemisphere 47.8
1561 Female, age 67, right hemisphere 40.3
1552 Male, age 75, left hemisphere 36.9
1553 Male, age 75, right hemisphere 33.7
1554 Male, age 74, left hemisphere 31.1
1555 Male, age 74, right hemisphere 30.6
1559 Female, age 85, right hemisphere 24.4
1550 Male, age 61, left hemisphere 21.4
1556 Female, age 94, left hemisphere 20.9
1557 Female, age 94, right hemisphere 18.0
1558 Female, age 85, left hemisphere 17.8
1551 Male, age 61, right hemisphere 17.0
Superior frontal gyrus
nTPM: 30.2
1566 Male, age 74, right hemisphere 48.6
1571 Female, age 67, right hemisphere 43.7
1567 Female, age 94, left hemisphere 38.0
1570 Female, age 85, right hemisphere 35.6
1568 Female, age 94, right hemisphere 32.1
1564 Male, age 75, left hemisphere 23.3
1569 Female, age 85, left hemisphere 23.0
1562 Male, age 61, left hemisphere 21.7
1565 Male, age 75, right hemisphere 19.7
1563 Male, age 61, right hemisphere 16.2
Temporal cortex
nTPM: 30.7
1591 Male, age 75, right hemisphere 49.7
1593 Male, age 74, right hemisphere 33.2
1596 Female, age 85, right hemisphere 31.3
1590 Male, age 61, right hemisphere 30.3
1592 Male, age 74, left hemisphere 26.9
1594 Female, age 94, left hemisphere 22.0
1595 Female, age 94, right hemisphere 21.5
Ventrolateral prefrontal cortex
nTPM: 23.5
1453 Male, age 74, right hemisphere 28.4
1457 Female, age 67, right hemisphere 28.3
1456 Female, age 67, left hemisphere 27.5
1452 Male, age 74, left hemisphere 22.1
1451 Male, age 75, right hemisphere 21.3
1454 Female, age 94, left hemisphere 19.1
1455 Female, age 85, right hemisphere 17.8
Ventromedial prefrontal cortex
nTPM: 18.8
1438 Female, age 67, left hemisphere 33.0
1434 Male, age 75, right hemisphere 22.1
1437 Female, age 85, right hemisphere 17.7
1433 Male, age 61, right hemisphere 15.7
1432 Male, age 61, left hemisphere 15.1
1436 Female, age 85, left hemisphere 14.4
1435 Female, age 94, right hemisphere 13.8

CEREBRAL CORTEX - GTEx RNA-seqi
Average nTPM 21.9
GTEx sample id Sample description nTPM
Brain - Anterior cingulate cortex (BA24)
Average nTPM: 21.9
Samples: 176

Max nTPM: 83.1
Min nTPM: 8.5
Std nTPM: 9.8
Median nTPM: 20.3
GTEX-N7MT-0011-R3a-SM-2I3GC 60-69 years, female 83.1
GTEX-16XZZ-0011-R3a-SM-7IGLH 60-69 years, male 59.1
GTEX-1EH9U-0011-R3b-SM-CL534 60-69 years, male 51.0
GTEX-NPJ8-0011-R3a-SM-2HMIW 40-49 years, male 47.8
GTEX-X4EP-0011-R3A-SM-3P626 60-69 years, female 46.0
GTEX-1EN7A-0011-R3a-SM-9OSVT 40-49 years, male 43.4
GTEX-UTHO-0011-R3A-SM-3GIK8 60-69 years, male 40.3
GTEX-14PJM-0011-R3b-SM-5ZZV9 50-59 years, female 40.1
GTEX-13RTL-0011-R3a-SM-5P9JP 40-49 years, male 38.5
GTEX-139T8-0011-R3b-SM-5HL4R 60-69 years, male 37.4
GTEX-1F52S-0011-R3a-SM-CKZNI 60-69 years, female 36.3
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Brain - Cortex
Average nTPM: 17.9
Samples: 255

Max nTPM: 50.8
Min nTPM: 7.3
Std nTPM: 6.6
Median nTPM: 16.1
GTEX-1F7RK-1826-SM-7RHI4 20-29 years, female 50.8
GTEX-13G51-3026-SM-5IJB8 60-69 years, male 44.0
GTEX-1JJE9-2926-SM-CY8HV 70-79 years, male 38.4
GTEX-1IDFM-2826-SM-ACKWJ 60-69 years, male 37.8
GTEX-1C6VS-3026-SM-79OLA 60-69 years, male 37.5
GTEX-1GN1V-3126-SM-7PBZG 60-69 years, male 37.2
GTEX-1EN7A-3026-SM-7PBYT 40-49 years, male 36.9
GTEX-1GZHY-3126-SM-9QEHH 50-59 years, female 34.5
GTEX-1445S-3026-SM-5O9BR 60-69 years, male 33.7
GTEX-1CAV2-2726-SM-7IGNN 40-49 years, female 33.6
GTEX-13JVG-3126-SM-5L3FH 60-69 years, male 32.8
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Brain - Frontal Cortex (BA9)
Average nTPM: 19.3
Samples: 209

Max nTPM: 52.5
Min nTPM: 6.3
Std nTPM: 8.6
Median nTPM: 17.0
GTEX-1LC47-0011-R10b-SM-EYYWE 60-69 years, male 52.5
GTEX-15UF6-0011-R10b-SM-9OSVF 70-79 years, female 49.5
GTEX-1CB4J-0011-R10a-SM-9WG63 60-69 years, male 45.3
GTEX-11TUW-0011-R10a-SM-DO924 60-69 years, male 44.5
GTEX-XMD1-0011-R10A-SM-4AT4A 60-69 years, male 43.0
GTEX-1445S-0011-R10a-SM-5PNWB 60-69 years, male 42.0
GTEX-16NPV-0011-R10a-SM-79OKA 50-59 years, female 40.8
GTEX-1IL2V-0011-R10a-SM-CL55A 70-79 years, male 37.9
GTEX-131XW-0011-R10a-SM-5DUVA 50-59 years, female 37.2
GTEX-X4XY-0011-R10B-SM-46MWS 60-69 years, male 36.7
GTEX-1C6VQ-0011-R10b-SM-7P8Q1 50-59 years, male 36.7
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CEREBRAL CORTEX - FANTOM5 CAGEi
Max Scaled Tags Per Million 64.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Occipital cortex
Scaled Tags Per Million: 41.3
FF:10163-103B1 76 years, female 41.3
Postcentral gyrus
Scaled Tags Per Million: 52.4
FF:10032-101E5 44-52 years, mixed 52.4
Frontal lobe
Scaled Tags Per Million: 44.3
FF:10040-101F4 32-61 years, mixed 44.3
Insula
Scaled Tags Per Million: 39.7
FF:10039-101F3 20-68 years, mixed 39.7
Medial frontal gyrus
Scaled Tags Per Million: 33.2
FF:10150-102I6 76 years, female 33.2
Medial temporal gyrus
Scaled Tags Per Million: 35.7
FF:10156-103A3 76 years, female 38.7
FF:10183-103D3 60 years, female 32.8
Occipital lobe
Scaled Tags Per Million: 59.2
FF:10076-102A4 27 years, male 59.2
Occipital pole
Scaled Tags Per Million: 52.7
FF:10036-101E9 22-68 years, mixed 52.7
Paracentral gyrus
Scaled Tags Per Million: 64.0
FF:10035-101E8 22-69 years, mixed 64.0
Parietal lobe
Scaled Tags Per Million: 44.9
FF:10034-101E7 35-89 years, mixed 61.1
FF:10171-103B9 60 years, female 39.2
FF:10157-103A4 76 years, female 34.5
Temporal lobe
Scaled Tags Per Million: 41.6
FF:10031-101E4 32-61 years, mixed 41.6

CEREBRAL CORTEX - Pig RNA-seqi
Average nTPM 10.5
Pig sample Sample description nTPM
Occipital cortex
nTPM: 10.3
Samples: 4

Max nTPM: 11.1
Min nTPM: 9.7
Sample A Female 9.7
Sample B Female 10.5
Sample C Male 11.1
Sample D Male 9.8
Retrosplenial cortex
nTPM: 10.5
Samples: 4

Max nTPM: 12.6
Min nTPM: 9.2
Sample A Female 12.6
Sample B Female 10.0
Sample C Male 10.1
Sample D Male 9.2
Cingulate cortex
nTPM: 9.7
Samples: 4

Max nTPM: 10.2
Min nTPM: 9.3
Sample A Female 9.9
Sample B Female 9.3
Sample C Male 10.2
Sample D Male 9.3
Insular cortex
nTPM: 9.8
Samples: 4

Max nTPM: 10.9
Min nTPM: 8.8
Sample A Female 9.6
Sample B Female 10.9
Sample C Male 9.9
Sample D Male 8.8
Motor cortex
nTPM: 10.4
Samples: 4

Max nTPM: 12.0
Min nTPM: 9.5
Sample A Female 9.8
Sample B Female 9.5
Sample C Male 12.0
Sample D Male 10.2
Prefrontal cortex
nTPM: 9.8
Samples: 4

Max nTPM: 11.0
Min nTPM: 8.7
Sample A Female 11.0
Sample B Female 8.7
Sample C Male 10.0
Sample D Male 9.6
Somatosensory cortex
nTPM: 9.9
Samples: 3

Max nTPM: 10.6
Min nTPM: 9.4
Sample B Female 9.4
Sample C Male 10.6
Sample D Male 9.7
Temporal cortex
nTPM: 9.3
Samples: 4

Max nTPM: 9.8
Min nTPM: 8.9
Sample A Female 9.3
Sample B Female 8.9
Sample C Male 9.8
Sample D Male 9.1

CEREBRAL CORTEX - Mouse RNA-seqi
Average nTPM 45.4
Mouse sample Sample description nTPM
Occipital cortex
nTPM: 45.0
Samples: 4

Max nTPM: 49.4
Min nTPM: 39.4
Sample A Male 44.8
Sample B Male 49.4
Sample C Female 46.4
Sample D Female 39.4
Frontal cortex
nTPM: 40.5
Samples: 4

Max nTPM: 45.1
Min nTPM: 35.9
Sample A Male 45.1
Sample B Male 39.8
Sample C Female 41.3
Sample D Female 35.9
Retrosplenial and cingulate cortex
nTPM: 43.0
Samples: 4

Max nTPM: 46.9
Min nTPM: 39.6
Sample A Male 42.5
Sample B Male 43.1
Sample C Female 39.6
Sample D Female 46.9
Somatosensory cortex
nTPM: 45.4
Samples: 4

Max nTPM: 47.6
Min nTPM: 44.5
Sample A Male 44.7
Sample B Male 47.6
Sample C Female 44.5
Sample D Female 44.7

CEREBRAL CORTEX - Allen Mouse ISHi
Max Expression energy 2.5
Allen experiment id Experiment description Expression energy
Cerebral cortex
Expression energy: 2.5
69838712 Antisense, RP_050321_01_A10, Mouse strain C57BL/6J (56 days, male) 3.3
75233089 Antisense, RP_060220_02_G06, Mouse strain C57BL/6J (56 days, male) 1.6

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