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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA030105
Moderate to strong cytoplasmic and nuclear positivity was observed in most normal tissues. Breast, prostate, lung, spleen, skin and bile ducts were generally weakly stained.
HPA030106
Some squamous epithelium displayed moderate cytoplasmic immunoreactivity in superficial cells and nuclear positivity in basal layer. Trophoblasts, exocrine pancreas and renal tubules showed moderate nuclear and cytoplasmic positivity. A fraction of neuronal cells in CNS showed moderate cytoplasmic immunoreactivity. Remaining normal tissues were weakly stained or negative.
HPA030107
Strong luminal membranous positivity was observed in glandular cells of intestinal tract, liver and renal tubuli. Gall bladder and a subset of neuronal cells of CNS showed moderate cytoplasmic stained. Remaining normal tissues were weakly stained or negative.
The Human Protein Atlas project is funded
