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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Glial cells:
Not detected
Neuronal cells:
Medium
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
31.6
nTPM
HPA Brain:
122.2
nTPM
GTEx:
31.6
nTPM
Pig:
33.8
nTPM
Mouse:
26.8
nTPM
Allen mouse:
6.1
Expression energy
HIPPOCAMPUS - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA044009
Glial cells
Not detected
Neuronal cells
Medium
HIPPOCAMPAL FORMATION - HPA Brain RNA-seq
Max nTPM
122.2
Sample id
Sample description
nTPM
Hippocampus nTPM: 81.9
2148
Female, age 91, left hemisphere
147.7
1855
Male, age 76, left hemisphere
104.1
2621
Female, age 67, right hemisphere
74.4
1898
Male, age 80, left hemisphere
62.9
1911
Female, age 85, right hemisphere
59.5
2529
Female, age 94, left hemisphere
42.7
Dentate gyrus nTPM: 122.2
2531
Female, age 67, both hemispheres
244.2
1927
Female, age 91, both hemispheres
137.8
2528
Male, age 74, both hemispheres
113.9
2246
Female, age 85, both hemispheres
107.4
2010
Male, age 76, both hemispheres
90.7
2530
Female, age 94, left hemisphere
39.0
Entorhinal gyrus nTPM: 36.2
1787
Male, age 76, left hemisphere
40.2
1938
Female, age 85, left hemisphere
39.3
2613
Female, age 94, left hemisphere
38.3
2117
Female, age 91, right hemisphere
34.4
2764
Male, age 80, right hemisphere
33.8
2686
Male, age 75, right hemisphere
31.4
Hippocampus, CA1 nTPM: 121.9
2045
Male, age 76, both hemispheres
317.3
1873
Female, age 85, both hemispheres
91.8
2082
Female, age 91, right hemisphere
80.3
2749
Male, age 80, left hemisphere
63.3
2527
Male, age 74, both hemispheres
56.6
Hippocampus, CA2 nTPM: 50.1
1892
Male, age 76, both hemispheres
73.2
2113
Female, age 91, right hemisphere
51.6
1940
Female, age 85, left hemisphere
51.0
1963
Male, age 80, left hemisphere
45.8
2249
Male, age 74, both hemispheres
39.8
2437
Female, age 94, left hemisphere
39.3
Hippocampus, CA3 nTPM: 121.8
2620
Female, age 94, left hemisphere
288.4
2861
Female, age 67, both hemispheres
153.6
1867
Male, age 76, both hemispheres
83.7
1891
Female, age 85, both hemispheres
81.6
2137
Male, age 80, left hemisphere
68.3
2436
Male, age 74, both hemispheres
55.2
Parahippocampal cortex nTPM: 41.4
1933
Female, age 85, both hemispheres
54.3
2693
Female, age 94, both hemispheres
54.3
2245
Female, age 91, both hemispheres
45.4
1850
Male, age 80, both hemispheres
41.7
2250
Female, age 67, right hemisphere
41.1
2532
Female, age 72, left hemisphere
39.0
2018
Male, age 76, both hemispheres
38.0
1990
Female, age 91, right hemisphere
35.2
2692
Male, age 74, both hemispheres
34.0
2622
Female, age 67, right hemisphere
31.2
Perirhinal gyrus nTPM: 53.8
2521
Female, age 94, right hemisphere
79.3
1847
Female, age 91, left hemisphere
57.3
1794
Male, age 80, right hemisphere
50.7
1841
Female, age 85, right hemisphere
41.5
2848
Male, age 76, right hemisphere
40.4
Subiculum nTPM: 55.0
2729
Female, age 91, right hemisphere
124.0
1977
Female, age 85, both hemispheres
64.0
1901
Male, age 80, both hemispheres
43.6
2619
Male, age 74, both hemispheres
36.3
2042
Male, age 76, both hemispheres
32.0
2438
Female, age 94, left hemisphere
30.1
HIPPOCAMPAL FORMATION - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Average nTPM
31.6
GTEx sample id
Sample description
nTPM
Brain - Hippocampus Average nTPM: 31.6
Samples: 197
Max nTPM: 264.4
Min nTPM: 4.9
Std nTPM: 35.1
Median nTPM: 22.0
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Average nTPM
26.8
Mouse sample
Sample description
nTPM
Entorhinal cortex nTPM: 24.6
Samples: 4
Max nTPM: 27.8
Min nTPM: 21.4
Sample A
Male
21.4
Sample B
Male
23.0
Sample C
Female
26.3
Sample D
Female
27.8
Hippocampal formation nTPM: 26.8
Samples: 4
Max nTPM: 28.4
Min nTPM: 24.4
Sample A
Male
27.6
Sample B
Male
26.6
Sample C
Female
28.4
Sample D
Female
24.4
HIPPOCAMPAL FORMATION - Allen Mouse ISHi
In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.
The Human Protein Atlas project is funded
