CEREBRAL CORTEX - Expression summary
Protein expression
Cerebral cortexi
h
m
l
n
Endothelial cells: Low
Glial cells: Low
Neuronal cells: Not detected
Neuropil: Low
RNA expressioni
Consensus:45.8 nTPM
HPA:45.8 nTPM
HPA Brain:150.1 nTPM
HPA PFC Brain:57.4 nTPM
GTEx:35.9 nTPM
FANTOM5:173.4 Scaled Tags Per Million
Pig:131.1 nTPM
Mouse:27.0 nTPM
Allen mouse:13.2 Expression energy

CEREBRAL CORTEX - Antibody stainingi
Antibody HPA004184Antibody HPA063840
Endothelial cells Not detectedLow
Glial cells Not detectedLow
Neuronal cells Not detectedNot detected
Neuropil Not detectedLow





CEREBRAL CORTEX - HPA RNA-seqi
Average nTPM 45.8
N/A
Male, age 5
Cerebral cortex sample 48
nTPM: 41
overview
Female, age 40
Cerebral cortex sample 105
nTPM: 45.7
Cell types%
Neuronal cells:
35

Glial cells and endothelial cells:
65
overview
Male, age 70
Cerebral cortex sample 106
nTPM: 50.6
Cell types%
Neuronal cells:
35

Glial cells and endothelial cells:
65

CEREBRAL CORTEX - HPA Brain RNA-seq
Max nTPM 150.1
Sample id Sample description nTPM
Angular gyrus
nTPM: 121.9
2103 Male, age 75, left hemisphere 145.5
1790 Male, age 76, right hemisphere 132.0
1866 Male, age 76, both hemispheres 127.3
2260 Female, age 72, left hemisphere 123.6
2602 Female, age 94, right hemisphere 122.5
2722 Male, age 61, left hemisphere 121.0
2221 Female, age 67, right hemisphere 104.0
2265 Female, age 91, left hemisphere 99.5
Anterior cingulate cortex, supragenual-dorsal
nTPM: 108.7
1896 Female, age 85, right hemisphere 134.1
2342 Female, age 94, right hemisphere 115.9
2547 Male, age 74, left hemisphere 103.9
2472 Male, age 75, left hemisphere 101.1
2478 Female, age 67, right hemisphere 88.3
Anterior cingulate cortex, supragenual-ventral
nTPM: 134.1
2479 Female, age 67, right hemisphere 168.3
1950 Female, age 85, right hemisphere 143.9
1761 Male, age 74, left hemisphere 123.7
2538 Male, age 75, left hemisphere 117.8
1755 Female, age 94, right hemisphere 116.5
Anterior insular cortex, dorsal
nTPM: 111.2
2670 Male, age 75, left hemisphere 144.9
2506 Female, age 94, right hemisphere 107.7
2001 Male, age 76, right hemisphere 104.0
2235 Female, age 91, right hemisphere 88.1
Anterior insular cortex, ventral
nTPM: 125.3
2596 Male, age 75, left hemisphere 188.7
1925 Female, age 91, left hemisphere 123.7
2757 Male, age 61, right hemisphere 115.3
2262 Female, age 67, right hemisphere 111.5
2507 Female, age 94, left hemisphere 109.0
1852 Male, age 76, left hemisphere 103.4
Area parastriata, inferior
nTPM: 142.5
2509 Female, age 94, left hemisphere 211.8
1789 Male, age 76, right hemisphere 157.8
2234 Male, age 75, left hemisphere 152.1
1758 Female, age 72, right hemisphere 129.1
2268 Male, age 61, right hemisphere 128.3
2421 Female, age 91, left hemisphere 112.9
1760 Female, age 67, left hemisphere 105.5
Area parastriata, parietal
nTPM: 138.6
2233 Male, age 61, right hemisphere 172.8
2420 Male, age 75, left hemisphere 153.0
2236 Female, age 91, left hemisphere 123.6
1785 Male, age 76, right hemisphere 122.9
2680 Female, age 94, right hemisphere 120.8
Area parastriata, superior
nTPM: 149.0
2435 Male, age 61, left hemisphere 189.8
2604 Female, age 94, right hemisphere 175.6
2881 Male, age 76, left hemisphere 139.2
2684 Female, age 67, left hemisphere 134.3
2419 Male, age 75, right hemisphere 133.0
1773 Female, age 91, left hemisphere 122.0
Area parastriata, temporal
nTPM: 131.0
2267 Male, age 61, right hemisphere 144.5
2681 Female, age 94, right hemisphere 132.8
2471 Male, age 75, left hemisphere 128.3
1804 Male, age 76, right hemisphere 127.4
2424 Female, age 67, left hemisphere 122.2
Area striata
nTPM: 130.4
1884 Male, age 76, left hemisphere 224.9
2002 Female, age 91, right hemisphere 117.3
2417 Male, age 61, right hemisphere 116.1
2679 Female, age 94, right hemisphere 108.7
1753 Female, age 72, right hemisphere 108.6
2427 Female, age 91, left hemisphere 106.8
Claustrum
nTPM: 150.1
2292 Female, age 85, both hemispheres 187.7
1956 Male, age 74, unknown 182.0
2198 Male, age 80, both hemispheres 154.2
2491 Male, age 75, both hemispheres 149.9
2568 Male, age 61, both hemispheres 148.8
2392 Female, age 94, both hemispheres 139.4
2196 Female, age 79, unknown 138.0
2284 Female, age 91, both hemispheres 128.1
2645 Female, age 72, unknown 122.8
Frontal eye field
nTPM: 126.5
2147 Male, age 61, left hemisphere 165.2
2441 Male, age 75, left hemisphere 121.3
2761 Female, age 94, left hemisphere 116.4
2543 Male, age 74, left hemisphere 103.2
Frontal operculum
nTPM: 126.4
2030 Male, age 61, right hemisphere 176.7
2781 Female, age 85, right hemisphere 117.9
2348 Male, age 75, left hemisphere 84.7
Fusiform gyrus
nTPM: 134.4
2431 Male, age 75, right hemisphere 179.4
1807 Male, age 76, left hemisphere 141.9
2112 Male, age 80, both hemispheres 133.4
2784 Female, age 85, left hemisphere 130.3
2433 Female, age 72, left hemisphere 124.3
2617 Female, age 94, left hemisphere 123.1
2074 Female, age 91, left hemisphere 108.7
Inferior frontal gyrus, opercular
nTPM: 118.7
2874 Female, age 85, right hemisphere 143.4
2865 Male, age 61, left hemisphere 132.7
2873 Female, age 85, left hemisphere 127.8
2867 Male, age 75, left hemisphere 122.9
2875 Female, age 67, left hemisphere 117.9
2869 Male, age 74, left hemisphere 114.9
2866 Male, age 61, right hemisphere 110.4
2868 Male, age 75, right hemisphere 108.8
2872 Female, age 94, right hemisphere 107.8
2871 Female, age 94, left hemisphere 100.2
Inferior parietal lobule
nTPM: 117.1
2876 Male, age 76, right hemisphere 143.8
2606 Female, age 67, right hemisphere 113.3
2418 Male, age 75, left hemisphere 109.9
2599 Female, age 94, left hemisphere 101.5
Inferior temporal gyrus
nTPM: 125.3
2689 Female, age 94, right hemisphere 149.9
1880 Male, age 80, right hemisphere 137.2
1808 Male, age 76, left hemisphere 131.6
2430 Male, age 75, right hemisphere 117.3
1970 Female, age 85, right hemisphere 108.7
1965 Female, age 91, left hemisphere 107.1
Intraparietal deep sulcus
nTPM: 141.1
2600 Female, age 94, right hemisphere 165.1
2102 Female, age 91, left hemisphere 157.1
2230 Male, age 61, right hemisphere 143.9
2607 Female, age 67, right hemisphere 140.9
2669 Male, age 75, left hemisphere 124.1
2798 Male, age 76, left hemisphere 115.5
Lingual gyrus
nTPM: 128.8
2838 Male, age 80, right hemisphere 138.8
1893 Male, age 76, left hemisphere 135.6
2618 Female, age 94, left hemisphere 130.0
2073 Female, age 85, left hemisphere 124.6
2688 Male, age 75, right hemisphere 115.0
Middle cingulate cortex
nTPM: 126.7
2539 Male, age 75, left hemisphere 150.9
2640 Female, age 94, right hemisphere 143.1
2028 Female, age 85, left hemisphere 122.5
2633 Male, age 74, left hemisphere 113.1
2357 Female, age 67, right hemisphere 104.0
Middle temporal gyrus
nTPM: 126.4
1819 Male, age 80, right hemisphere 148.4
1799 Male, age 76, left hemisphere 141.2
2616 Female, age 94, left hemisphere 127.9
2611 Male, age 75, right hemisphere 109.6
2034 Female, age 91, right hemisphere 105.1
Occipital cortex
nTPM: 120.2
2677 Female, age 67, right hemisphere 138.4
2426 Male, age 75, midline 118.1
2470 Male, age 75, right hemisphere 116.9
1842 Male, age 76, right hemisphere 116.5
2608 Female, age 67, both hemispheres 111.3
Olfactory area
nTPM: 114.5
1805 Female, age 85, right hemisphere 137.5
2542 Male, age 74, left hemisphere 130.4
2352 Female, age 94, right hemisphere 124.8
2440 Male, age 75, left hemisphere 114.6
2756 Female, age 67, right hemisphere 90.3
2222 Female, age 67, right hemisphere 89.6
Olfactory tubercle
nTPM: 112.6
1846 Male, age 80, right hemisphere 120.7
2856 Male, age 75, right hemisphere 111.4
1998 Female, age 91, both hemispheres 110.1
2487 Female, age 94, left hemisphere 108.2
Orbitofrontal gyrus, anterior
nTPM: 130.2
2862 Female, age 85, left hemisphere 135.5
2864 Female, age 67, left hemisphere 131.4
2863 Female, age 85, right hemisphere 123.6
Paracentral lobule, anterior
nTPM: 128.6
1776 Female, age 85, right hemisphere 146.9
2340 Female, age 67, right hemisphere 135.6
1926 Male, age 61, left hemisphere 134.1
1754 Male, age 75, left hemisphere 123.0
2638 Female, age 94, right hemisphere 117.7
2474 Male, age 74, left hemisphere 114.3
Paracentral lobule, posterior
nTPM: 144.0
2345 Male, age 61, left hemisphere 158.2
1764 Male, age 74, right hemisphere 144.7
2446 Male, age 75, left hemisphere 141.0
2551 Female, age 94, right hemisphere 140.4
1775 Female, age 85, right hemisphere 135.4
Parietal operculum
nTPM: 105.0
2356 Female, age 67, right hemisphere 117.6
2719 Male, age 75, left hemisphere 104.8
2552 Female, age 94, right hemisphere 102.3
1763 Male, age 74, left hemisphere 95.5
Parieto-insular cortex
nTPM: 122.9
1976 Female, age 91, right hemisphere 136.8
2671 Male, age 75, left hemisphere 128.1
2232 Male, age 61, right hemisphere 126.0
2831 Male, age 76, right hemisphere 116.1
2508 Female, age 94, right hemisphere 107.5
Parieto-occipital transitional area
nTPM: 125.5
2270 Male, age 61, right hemisphere 144.9
2683 Female, age 67, left hemisphere 143.4
2674 Female, age 94, right hemisphere 118.9
1784 Male, age 76, right hemisphere 117.5
2468 Male, age 75, left hemisphere 102.7
Piriform cortex
nTPM: 149.0
2153 Female, age 85, left hemisphere 159.4
2347 Male, age 75, right hemisphere 138.6
Postcentral gyrus
nTPM: 128.7
2533 Male, age 75, right hemisphere 128.7
Postcentral gyrus, dorsal
nTPM: 137.5
2339 Female, age 67, right hemisphere 197.8
2477 Female, age 94, right hemisphere 137.3
1836 Female, age 85, right hemisphere 129.3
2151 Male, age 61, left hemisphere 127.6
2350 Male, age 75, left hemisphere 124.9
2544 Male, age 74, left hemisphere 108.0
Postcentral gyrus, middle
nTPM: 121.9
2248 Male, age 61, left hemisphere 131.7
1897 Female, age 85, right hemisphere 130.8
2545 Male, age 74, left hemisphere 125.1
2444 Male, age 75, left hemisphere 112.8
2146 Female, age 67, right hemisphere 109.3
Postcentral gyrus, ventral
nTPM: 137.5
2024 Female, age 85, right hemisphere 150.5
2836 Female, age 94, right hemisphere 139.1
2445 Male, age 75, left hemisphere 123.0
Posterior cingulate cortex
nTPM: 133.0
1759 Male, age 74, right hemisphere 135.1
2553 Female, age 94, right hemisphere 134.9
2473 Male, age 75, left hemisphere 129.1
Posterior cingulate cortex, dorsal
nTPM: 140.0
2343 Male, age 61, left hemisphere 178.3
2556 Female, age 67, right hemisphere 160.7
2634 Male, age 74, left hemisphere 138.4
2076 Female, age 85, right hemisphere 128.6
2540 Male, age 75, right hemisphere 122.0
2641 Female, age 94, right hemisphere 112.0
Posterior cingulate cortex, ventral
nTPM: 121.0
2541 Male, age 75, right hemisphere 154.8
2448 Female, age 67, right hemisphere 132.9
2346 Male, age 61, left hemisphere 121.6
1762 Female, age 94, right hemisphere 114.1
1994 Female, age 85, right hemisphere 107.1
2635 Male, age 74, left hemisphere 95.4
Posterior insular cortex
nTPM: 117.8
2231 Male, age 61, left hemisphere 125.7
2832 Female, age 91, right hemisphere 119.8
2603 Female, age 94, left hemisphere 117.4
2597 Male, age 75, left hemisphere 116.5
1823 Male, age 76, right hemisphere 114.3
2511 Female, age 67, right hemisphere 112.8
Precentral gyrus
nTPM: 123.9
2557 Male, age 75, right hemisphere 123.9
Precentral gyrus, dorsal
nTPM: 126.9
2442 Male, age 75, left hemisphere 145.2
1756 Male, age 74, left hemisphere 142.3
2476 Female, age 94, right hemisphere 123.4
2354 Female, age 67, right hemisphere 96.6
Precentral gyrus, middle
nTPM: 124.0
2443 Male, age 75, left hemisphere 161.5
1909 Male, age 61, left hemisphere 121.3
2475 Male, age 74, right hemisphere 115.1
2549 Female, age 94, right hemisphere 111.3
1969 Female, age 67, right hemisphere 110.6
Precentral gyrus, ventral
nTPM: 126.3
2662 Female, age 67, right hemisphere 165.3
2630 Male, age 75, left hemisphere 117.4
2550 Female, age 94, right hemisphere 113.8
2678 Male, age 74, left hemisphere 108.9
Precuneus
nTPM: 134.2
2467 Male, age 75, right hemisphere 146.9
1780 Female, age 91, right hemisphere 138.2
2510 Female, age 67, right hemisphere 137.9
2673 Female, age 94, right hemisphere 133.1
2594 Male, age 61, left hemisphere 130.0
1782 Male, age 76, right hemisphere 119.1
Premotor cortex, dorsal
nTPM: 139.3
2554 Female, age 67, right hemisphere 183.0
1878 Female, age 85, right hemisphere 134.0
2536 Male, age 75, left hemisphere 129.7
2631 Male, age 74, left hemisphere 125.4
2027 Male, age 61, left hemisphere 124.3
Premotor cortex, ventral
nTPM: 131.2
1757 Male, age 74, left hemisphere 151.3
1777 Female, age 67, left hemisphere 140.5
1779 Male, age 61, left hemisphere 140.5
2349 Male, age 75, left hemisphere 129.9
1881 Female, age 85, right hemisphere 123.3
2637 Female, age 94, right hemisphere 101.7
Retrosplenial cortex
nTPM: 118.7
1914 Male, age 76, right hemisphere 127.5
2675 Female, age 94, left hemisphere 116.2
1951 Male, age 61, right hemisphere 112.5
Subcentral gyrus, S2
nTPM: 129.2
2555 Female, age 67, right hemisphere 150.4
2072 Male, age 61, left hemisphere 145.5
2762 Male, age 74, left hemisphere 122.2
2351 Male, age 75, left hemisphere 121.2
2839 Female, age 94, right hemisphere 118.1
1964 Female, age 85, right hemisphere 117.8
Superior parietal lobule
nTPM: 134.4
1992 Female, age 91, right hemisphere 150.6
1800 Male, age 76, right hemisphere 143.3
2229 Male, age 61, right hemisphere 133.1
2672 Female, age 94, right hemisphere 122.8
2605 Female, age 67, right hemisphere 122.4
Superior temporal gyrus
nTPM: 119.8
1843 Male, age 76, left hemisphere 124.6
2687 Male, age 75, right hemisphere 122.6
2615 Female, age 94, left hemisphere 120.2
2025 Male, age 80, right hemisphere 119.4
1844 Female, age 91, left hemisphere 112.3
Supplementary motor cortex
nTPM: 126.4
2632 Male, age 74, left hemisphere 152.2
1993 Male, age 61, left hemisphere 124.5
2548 Female, age 94, right hemisphere 115.6
2537 Male, age 75, left hemisphere 113.1
Supramarginal gyrus
nTPM: 117.9
2415 Male, age 61, left hemisphere 138.7
1991 Female, age 91, right hemisphere 118.1
1798 Male, age 76, right hemisphere 111.1
2513 Female, age 72, left hemisphere 110.8
2601 Female, age 94, left hemisphere 110.7
Temporal pole
nTPM: 124.7
1853 Female, age 85, right hemisphere 141.7
1832 Female, age 91, left hemisphere 133.5
1826 Male, age 76, right hemisphere 125.5
2612 Female, age 94, left hemisphere 125.1
2518 Male, age 75, right hemisphere 97.9
Temporo-insular cortex, parainsular gyrus
nTPM: 123.1
2416 Male, age 61, right hemisphere 143.1
2512 Female, age 67, right hemisphere 139.6
2264 Female, age 91, right hemisphere 123.4
2676 Female, age 94, right hemisphere 118.4
2598 Male, age 75, left hemisphere 107.5
1802 Male, age 76, left hemisphere 106.4
Temporo-occipital transitional zone
nTPM: 127.0
1900 Male, age 76, left hemisphere 136.8
1793 Male, age 80, right hemisphere 135.2
2251 Female, age 85, right hemisphere 108.9
Transversal temporal gyrus, anterior
nTPM: 117.1
1910 Male, age 80, right hemisphere 121.1
1809 Male, age 76, right hemisphere 120.9
1888 Female, age 91, left hemisphere 118.8
2522 Female, age 94, left hemisphere 114.0
2610 Male, age 75, right hemisphere 110.8
Transversal temporal gyrus, posterior
nTPM: 125.6
2520 Male, age 75, right hemisphere 155.9
2833 Male, age 80, right hemisphere 132.0
2614 Female, age 94, left hemisphere 120.4
1922 Male, age 76, left hemisphere 115.6
1967 Female, age 91, right hemisphere 104.2

CEREBRAL CORTEX - HPA PFC Brain RNA-seq
Max nTPM 57.4
Sample id Sample description nTPM
Anterior cingulate gyrus, pregenual-dorsal
nTPM: 34.1
1514 Male, age 74, right hemisphere 51.1
1513 Male, age 74, left hemisphere 40.2
1512 Male, age 75, left hemisphere 35.6
1515 Female, age 94, right hemisphere 34.7
1511 Male, age 61, right hemisphere 32.6
1518 Female, age 67, right hemisphere 32.6
1510 Male, age 61, left hemisphere 31.3
1516 Female, age 85, left hemisphere 27.2
1517 Female, age 67, left hemisphere 22.1
Anterior cingulate gyrus, pregenual-ventral
nTPM: 30.7
1521 Male, age 74, left hemisphere 43.3
1523 Female, age 67, left hemisphere 30.8
1522 Male, age 74, right hemisphere 28.9
1520 Male, age 75, right hemisphere 26.8
1519 Male, age 61, left hemisphere 23.9
Anterior cingulate gyrus, subgenual
nTPM: 32.2
1530 Female, age 67, right hemisphere 44.3
1527 Male, age 74, left hemisphere 41.9
1524 Male, age 61, left hemisphere 33.3
1526 Male, age 75, right hemisphere 29.3
1528 Male, age 74, right hemisphere 27.0
1525 Male, age 75, left hemisphere 26.3
1529 Female, age 85, left hemisphere 23.0
Dorsolateral prefrontal cortex
nTPM: 44.4
1447 Female, age 94, left hemisphere 56.0
1448 Female, age 94, right hemisphere 54.7
1446 Male, age 74, right hemisphere 48.5
1445 Male, age 75, right hemisphere 45.4
1449 Female, age 85, right hemisphere 41.1
1444 Male, age 75, left hemisphere 37.0
1450 Female, age 67, right hemisphere 27.9
Dorsomedial prefrontal cortex
nTPM: 44.3
1443 Female, age 67, right hemisphere 61.6
1442 Male, age 75, right hemisphere 49.7
1441 Male, age 75, left hemisphere 49.6
1439 Male, age 61, left hemisphere 32.3
1440 Male, age 61, right hemisphere 28.2
Frontal cortex
nTPM: 50.8
1575 Male, age 75, right hemisphere 72.7
1574 Male, age 75, left hemisphere 69.4
1576 Male, age 74, left hemisphere 67.5
1572 Male, age 61, left hemisphere 64.0
1577 Male, age 74, right hemisphere 54.7
1583 Female, age 67, right hemisphere 53.0
1578 Female, age 94, left hemisphere 47.6
1579 Female, age 94, right hemisphere 46.5
1582 Female, age 67, left hemisphere 42.6
1573 Male, age 61, right hemisphere 37.5
1580 Female, age 85, left hemisphere 28.0
1581 Female, age 85, right hemisphere 26.5
Frontomarginal cortex
nTPM: 40.0
1473 Female, age 67, right hemisphere 56.0
1468 Male, age 74, left hemisphere 54.5
1470 Female, age 94, right hemisphere 49.2
1467 Male, age 75, right hemisphere 39.8
1469 Female, age 94, left hemisphere 38.6
1472 Female, age 67, left hemisphere 35.2
1466 Male, age 61, right hemisphere 32.5
1465 Male, age 61, left hemisphere 29.2
1471 Female, age 85, left hemisphere 24.9
Frontopolar cortex
nTPM: 39.3
1464 Female, age 67, right hemisphere 76.8
1462 Female, age 94, left hemisphere 40.2
1460 Male, age 75, left hemisphere 40.1
1461 Male, age 75, right hemisphere 31.5
1459 Male, age 61, right hemisphere 30.3
1463 Female, age 67, left hemisphere 29.3
1458 Male, age 61, left hemisphere 26.6
Gyrus rectus
nTPM: 39.8
1476 Male, age 75, left hemisphere 45.9
1474 Male, age 61, left hemisphere 45.7
1477 Male, age 75, right hemisphere 44.2
1481 Female, age 67, left hemisphere 42.9
1478 Female, age 94, left hemisphere 37.2
1479 Female, age 94, right hemisphere 36.5
1480 Female, age 85, left hemisphere 33.6
1475 Male, age 61, right hemisphere 32.6
Inferior frontal gyrus, orbital
nTPM: 44.1
1507 Female, age 85, left hemisphere 99.2
1504 Male, age 74, left hemisphere 57.0
1505 Male, age 74, right hemisphere 54.0
1509 Female, age 67, right hemisphere 44.6
1506 Female, age 94, left hemisphere 44.3
1502 Male, age 75, left hemisphere 33.6
1503 Male, age 75, right hemisphere 32.6
1500 Male, age 61, left hemisphere 31.0
1501 Male, age 61, right hemisphere 22.8
1508 Female, age 85, right hemisphere 22.1
Inferior frontal gyrus, triangular
nTPM: 35.3
1544 Male, age 75, right hemisphere 53.4
1545 Male, age 74, right hemisphere 40.1
1546 Female, age 94, right hemisphere 37.9
1543 Male, age 61, right hemisphere 34.5
1548 Female, age 85, right hemisphere 31.8
1547 Female, age 85, left hemisphere 30.8
1549 Female, age 67, left hemisphere 27.3
1542 Male, age 61, left hemisphere 26.4
Orbitofrontal gyrus, lateral
nTPM: 34.1
1499 Female, age 67, right hemisphere 46.0
1495 Female, age 94, left hemisphere 37.7
1497 Female, age 85, left hemisphere 37.6
1496 Female, age 94, right hemisphere 35.7
1494 Male, age 75, left hemisphere 30.8
1493 Male, age 61, right hemisphere 27.2
1498 Female, age 85, right hemisphere 23.6
Orbitofrontal gyrus, medial
nTPM: 49.3
1491 Female, age 67, left hemisphere 64.9
1486 Male, age 74, right hemisphere 63.4
1485 Male, age 74, left hemisphere 62.5
1484 Male, age 75, right hemisphere 52.4
1487 Female, age 94, left hemisphere 51.5
1482 Male, age 61, left hemisphere 49.8
1492 Female, age 67, right hemisphere 44.4
1483 Male, age 75, left hemisphere 43.9
1488 Female, age 94, right hemisphere 40.9
1490 Female, age 85, right hemisphere 37.0
1489 Female, age 85, left hemisphere 31.4
Orbitofrontal gyrus, posterior
nTPM: 35.7
1535 Male, age 74, left hemisphere 55.3
1534 Male, age 75, right hemisphere 45.9
1540 Female, age 67, left hemisphere 38.2
1533 Male, age 75, left hemisphere 37.0
1539 Female, age 85, right hemisphere 33.8
1531 Male, age 61, left hemisphere 31.8
1536 Female, age 94, left hemisphere 31.7
1541 Female, age 67, right hemisphere 31.7
1532 Male, age 61, right hemisphere 29.1
1538 Female, age 85, left hemisphere 29.1
1537 Female, age 94, right hemisphere 28.6
Subcallosal gyrus
nTPM: 45.2
1552 Male, age 75, left hemisphere 82.6
1553 Male, age 75, right hemisphere 66.8
1561 Female, age 67, right hemisphere 55.0
1550 Male, age 61, left hemisphere 50.9
1560 Female, age 67, left hemisphere 42.5
1557 Female, age 94, right hemisphere 40.7
1556 Female, age 94, left hemisphere 38.3
1555 Male, age 74, right hemisphere 36.1
1559 Female, age 85, right hemisphere 34.5
1551 Male, age 61, right hemisphere 32.8
1554 Male, age 74, left hemisphere 32.7
1558 Female, age 85, left hemisphere 29.3
Superior frontal gyrus
nTPM: 49.8
1566 Male, age 74, right hemisphere 88.7
1571 Female, age 67, right hemisphere 60.1
1565 Male, age 75, right hemisphere 56.9
1567 Female, age 94, left hemisphere 56.8
1568 Female, age 94, right hemisphere 49.8
1564 Male, age 75, left hemisphere 48.6
1562 Male, age 61, left hemisphere 36.3
1570 Female, age 85, right hemisphere 34.5
1569 Female, age 85, left hemisphere 34.4
1563 Male, age 61, right hemisphere 32.1
Temporal cortex
nTPM: 57.4
1592 Male, age 74, left hemisphere 88.2
1591 Male, age 75, right hemisphere 84.9
1590 Male, age 61, right hemisphere 52.8
1595 Female, age 94, right hemisphere 49.2
1593 Male, age 74, right hemisphere 46.2
1594 Female, age 94, left hemisphere 41.0
1596 Female, age 85, right hemisphere 39.4
Ventrolateral prefrontal cortex
nTPM: 44.5
1456 Female, age 67, left hemisphere 53.0
1454 Female, age 94, left hemisphere 47.9
1453 Male, age 74, right hemisphere 45.9
1457 Female, age 67, right hemisphere 45.9
1451 Male, age 75, right hemisphere 44.7
1452 Male, age 74, left hemisphere 40.5
1455 Female, age 85, right hemisphere 34.0
Ventromedial prefrontal cortex
nTPM: 35.2
1438 Female, age 67, left hemisphere 50.6
1435 Female, age 94, right hemisphere 44.3
1433 Male, age 61, right hemisphere 36.8
1434 Male, age 75, right hemisphere 32.7
1432 Male, age 61, left hemisphere 29.8
1437 Female, age 85, right hemisphere 27.2
1436 Female, age 85, left hemisphere 25.3

CEREBRAL CORTEX - GTEx RNA-seqi
Average nTPM 35.9
GTEx sample id Sample description nTPM
29.332.939.820.955.40102030405060708090
Brain - Anterior cingulate cortex (BA24)
Average nTPM: 35.9
Samples: 176

Max nTPM: 97.2
Min nTPM: 9.2
Std nTPM: 11.3
Median nTPM: 32.9
GTEX-1EH9U-0011-R3b-SM-CL534 60-69 years, male 97.2
GTEX-N7MT-0011-R3a-SM-2I3GC 60-69 years, female 90.8
GTEX-XMD1-0011-R3B-SM-4AT5R 60-69 years, male 74.0
GTEX-14PJM-0011-R3b-SM-5ZZV9 50-59 years, female 69.3
GTEX-11ZVC-0011-R3a-SM-5BC6V 50-59 years, female 63.1
GTEX-139T8-0011-R3b-SM-5HL4R 60-69 years, male 61.3
GTEX-1HR98-0011-R3b-SM-A9G1U 60-69 years, male 60.0
GTEX-14E7W-0011-R3b-SM-5YYB5 70-79 years, male 59.8
GTEX-X4XY-0011-R3B-SM-EXOHI 60-69 years, male 59.8
GTEX-NPJ8-0011-R3a-SM-2HMIW 40-49 years, male 59.2
GTEX-1HB9E-0011-R3a-SM-ARL7D 50-59 years, male 56.8
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25.828.232.517.241.70102030405060708090
Brain - Cortex
Average nTPM: 30.6
Samples: 255

Max nTPM: 99.8
Min nTPM: 17.2
Std nTPM: 9.4
Median nTPM: 28.2
GTEX-1HFI6-3026-SM-CNPPJ 40-49 years, male 99.8
GTEX-13G51-3026-SM-5IJB8 60-69 years, male 83.9
GTEX-1F7RK-1826-SM-7RHI4 20-29 years, female 72.7
GTEX-1HB9E-2926-SM-D4P3S 50-59 years, male 67.4
GTEX-1QP6S-2926-SM-DTXF8 40-49 years, male 60.9
GTEX-N7MT-1126-SM-CYPQY 60-69 years, female 57.4
GTEX-1CAV2-2726-SM-7IGNN 40-49 years, female 53.4
GTEX-1B8SG-1726-SM-73KXK 50-59 years, male 53.3
GTEX-1HUB1-2926-SM-ACKXA 60-69 years, male 53.3
GTEX-1GN1V-3126-SM-7PBZG 60-69 years, male 49.5
GTEX-ZAJG-3126-SM-5HL9J 50-59 years, female 48.5
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28.632.036.317.647.8020406080100120140160180200220240
Brain - Frontal Cortex (BA9)
Average nTPM: 35.9
Samples: 209

Max nTPM: 252.0
Min nTPM: 17.6
Std nTPM: 22.1
Median nTPM: 32.0
GTEX-X4XY-0011-R10B-SM-46MWS 60-69 years, male 252.0
GTEX-1IL2V-0011-R10a-SM-CL55A 70-79 years, male 152.6
GTEX-ZE7O-0011-R10a-SM-57WAZ 50-59 years, female 144.2
GTEX-11TTK-0011-R10b-SM-DO925 60-69 years, female 143.0
GTEX-XMD1-0011-R10A-SM-4AT4A 60-69 years, male 110.8
GTEX-13JVG-0011-R10b-SM-5KM2P 60-69 years, male 69.9
GTEX-1H1CY-0011-R10a-SM-CE6SD 60-69 years, female 60.2
GTEX-ZDXO-0011-R10a-SM-4WWD8 60-69 years, male 58.3
GTEX-ZXG5-0011-R10a-SM-57WDD 60-69 years, male 55.1
GTEX-13FLW-0011-R10b-SM-5LZZF 50-59 years, male 51.0
GTEX-1HR9M-0011-R10a-SM-CM2SU 60-69 years, male 49.4
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CEREBRAL CORTEX - FANTOM5 CAGEi
Max Scaled Tags Per Million 173.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Occipital cortex
Scaled Tags Per Million: 163.8
FF:10163-103B1 76 years, female 163.8
Postcentral gyrus
Scaled Tags Per Million: 120.2
FF:10032-101E5 44-52 years, mixed 120.2
Frontal lobe
Scaled Tags Per Million: 144.8
FF:10040-101F4 32-61 years, mixed 144.8
Insula
Scaled Tags Per Million: 135.5
FF:10039-101F3 20-68 years, mixed 135.5
Medial frontal gyrus
Scaled Tags Per Million: 145.5
FF:10150-102I6 76 years, female 145.5
Medial temporal gyrus
Scaled Tags Per Million: 144.7
FF:10156-103A3 76 years, female 150.1
FF:10183-103D3 60 years, female 139.2
Occipital lobe
Scaled Tags Per Million: 173.4
FF:10076-102A4 27 years, male 173.4
Occipital pole
Scaled Tags Per Million: 117.5
FF:10036-101E9 22-68 years, mixed 117.5
Paracentral gyrus
Scaled Tags Per Million: 151.2
FF:10035-101E8 22-69 years, mixed 151.2
Parietal lobe
Scaled Tags Per Million: 161.3
FF:10171-103B9 60 years, female 177.5
FF:10034-101E7 35-89 years, mixed 161.0
FF:10157-103A4 76 years, female 145.3
Temporal lobe
Scaled Tags Per Million: 117.0
FF:10031-101E4 32-61 years, mixed 117.0

CEREBRAL CORTEX - Pig RNA-seqi
Average nTPM 131.1
Pig sample Sample description nTPM
121.6124.9128.3114.9135.00102030405060708090100110120130
 		Occipital cortex
nTPM: 124.9
Samples: 4

Max nTPM: 135.0
Min nTPM: 114.9
Sample A Female 123.8
Sample B Female 114.9
Sample C Male 135.0
Sample D Male 126.0
118.9122.1126.7111.8138.10102030405060708090100110120130
 		Retrosplenial cortex
nTPM: 123.5
Samples: 4

Max nTPM: 138.1
Min nTPM: 111.8
Sample A Female 138.1
Sample B Female 111.8
Sample C Male 121.3
Sample D Male 122.9
116.8120.0120.2120.0120.60102030405060708090100110120
 		Cingulate cortex
nTPM: 117.0
Samples: 4

Max nTPM: 120.6
Min nTPM: 107.3
Sample A Female 120.0
Sample B Female 107.3
Sample C Male 120.6
Sample D Male 120.0
119.4123.7125.7111.8126.20102030405060708090100110120
 		Insular cortex
nTPM: 121.4
Samples: 4

Max nTPM: 126.2
Min nTPM: 111.8
Sample A Female 125.5
Sample B Female 111.8
Sample C Male 121.9
Sample D Male 126.2
126.4132.7137.3120.5138.40102030405060708090100110120130
 		Motor cortex
nTPM: 131.1
Samples: 4

Max nTPM: 138.4
Min nTPM: 120.5
Sample A Female 136.9
Sample B Female 120.5
Sample C Male 138.4
Sample D Male 128.4
117.4122.8132.8117.2146.6020406080100120140
 		Prefrontal cortex
nTPM: 127.4
Samples: 4

Max nTPM: 146.6
Min nTPM: 117.2
Sample A Female 146.6
Sample B Female 117.2
Sample C Male 117.4
Sample D Male 128.2
120.3129.3132.8111.2136.20102030405060708090100110120130
 		Somatosensory cortex
nTPM: 125.6
Samples: 3

Max nTPM: 136.2
Min nTPM: 111.2
Sample B Female 111.2
Sample C Male 129.3
Sample D Male 136.2
118.6123.5128.1115.3130.40102030405060708090100110120130
 		Temporal cortex
nTPM: 123.2
Samples: 4

Max nTPM: 130.4
Min nTPM: 115.3
Sample A Female 115.3
Sample B Female 127.3
Sample C Male 130.4
Sample D Male 119.7

CEREBRAL CORTEX - Mouse RNA-seqi
Average nTPM 27.0
Mouse sample Sample description nTPM
24.324.724.924.625.0024681012141618202224
 		Occipital cortex
nTPM: 24.5
Samples: 4

Max nTPM: 25.0
Min nTPM: 23.5
Sample A Male 23.5
Sample B Male 24.6
Sample C Female 25.0
Sample D Female 24.8
26.127.428.324.928.60246810121416182022242628
 		Frontal cortex
nTPM: 27.1
Samples: 4

Max nTPM: 28.6
Min nTPM: 24.9
Sample A Male 28.2
Sample B Male 28.6
Sample C Female 26.5
Sample D Female 24.9
24.224.525.724.124.80246810121416182022242628
 		Retrosplenial and cingulate cortex
nTPM: 25.4
Samples: 4

Max nTPM: 28.5
Min nTPM: 24.1
Sample A Male 24.8
Sample B Male 24.1
Sample C Female 24.2
Sample D Female 28.5
24.825.326.124.327.902468101214161820222426
 		Somatosensory cortex
nTPM: 25.7
Samples: 4

Max nTPM: 27.9
Min nTPM: 24.3
Sample A Male 25.5
Sample B Male 25.0
Sample C Female 27.9
Sample D Female 24.3

CEREBRAL CORTEX - Allen Mouse ISHi
Max Expression energy 13.2
Allen experiment id Experiment description Expression energy
Cerebral cortex
Expression energy: 13.2
69407534 Antisense, RP_050414_01_H02, Mouse strain C57BL/6J (56 days, male) 13.2
71249084 Antisense, RP_050414_01_H02, Mouse strain C57BL/6J (56 days, male) 8.2

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