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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA008773
Normal tissues displayed moderate to strong cytoplasmic and/or membranous staining. Lymphoid tissue, heamtopoietic cells, cerebellum, epididymis, hippocampus, liver, ovary, islets of Langerhans, placenta, prostate and thyroid were weakly stained or negative.
HPA073203
A majority of normal tissues, including gastrointestinal tract, kidney and endometrium, showed cytoplasmic and membranous positivity of varying intensity. Nuclear and cytoplasmic positivity was observed in a subset of immune cells.
CAB025181
Strong membranous and cytoplasmic positivity was observed in parts of the intestine, exocrine pancreas and renal tubules while squamous epithelia generally showed moderate staining.
CAB062549
Strong cytoplasmic and membranous positivity is observed in renal tubules, stomach and glandular cells of uterus. Squamous epithelia, colon, exocrine pancreas and large intestine were moderately stained. Remaining normal tissues were weakly stained or negative.
CAB068179
Moderate membranous positivity was observed in colon, rectum, esophagus, endometrial glands and exocrine pancreas. Subset of renal tubules exhibited strong cytoplasmic and membranous staining. Remaining normal tissues were weakly stained or negative.