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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA034968
Most of the normal tissues displayed weak to moderate cytoplasmic positivity. Additional membranous staining was observed in respiratory epithelia, uterine glands, fallopian tubes, epididymis and urothelium. Renal tubules, Purkinje cells and cardiac myocytes were strongly stained. The liver, pancreas, ovary and lymphoid tissues were mainly negative.
HPA042013
Parietal cells of stomach, subset of renal tubules, smooth muscle cells, subset of exocrine glandular cells in pancreas and endothelial cells displayed strong cytoplasmic positivity. Placental trophoblasts, thyroid gland, heart myocytes and myoepithelial cells in breast were moderately stained. Remaining normal cells were weakly stained or negative.
HPA044141
Most normal tissues displayed moderate cytoplasmic positivity, often seen with a granular pattern. Gastrointestinal glands, renal tubules and heart myocytes were strongly stained. Respiratory epithelia and fallopian tube showed additional strong membranous positivity. Adipocytes were weakly stained or negative.
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