CEREBRAL CORTEX - Expression summary
Protein expression
Cerebral cortexi
h
m
l
n
Endothelial cells: Medium
Glial cells: Medium
Neuronal cells: Not detected
Neuropil: Low
RNA expressioni
Consensus:56.8 nTPM
HPA:23.0 nTPM
HPA Brain:38.2 nTPM
HPA PFC Brain:43.8 nTPM
GTEx:56.8 nTPM
FANTOM5:53.7 Scaled Tags Per Million
Pig:20.5 nTPM
Mouse:68.5 nTPM
Allen mouse:0.6 Expression energy

CEREBRAL CORTEX - Antibody stainingi
Antibody HPA044294
Endothelial cells Medium
Glial cells Medium
Neuronal cells Not detected
Neuropil Low


CEREBRAL CORTEX - HPA RNA-seqi
Average nTPM 23.0
N/A
Male, age 5
Cerebral cortex sample 48
nTPM: 27.5
overview
Female, age 40
Cerebral cortex sample 105
nTPM: 26.6
Cell types%
Neuronal cells:
35

Glial cells and endothelial cells:
65
overview
Male, age 70
Cerebral cortex sample 106
nTPM: 15
Cell types%
Neuronal cells:
35

Glial cells and endothelial cells:
65

CEREBRAL CORTEX - HPA Brain RNA-seq
Max nTPM 38.2
Sample id Sample description nTPM
Angular gyrus
nTPM: 29.6
2265 Female, age 91, left hemisphere 34.6
2260 Female, age 72, left hemisphere 32.9
1790 Male, age 76, right hemisphere 31.7
2103 Male, age 75, left hemisphere 30.3
1866 Male, age 76, both hemispheres 28.8
2602 Female, age 94, right hemisphere 28.7
2221 Female, age 67, right hemisphere 26.4
2722 Male, age 61, left hemisphere 23.8
Anterior cingulate cortex, supragenual-dorsal
nTPM: 31.7
2547 Male, age 74, left hemisphere 35.5
2342 Female, age 94, right hemisphere 31.4
2478 Female, age 67, right hemisphere 31.4
2472 Male, age 75, left hemisphere 31.3
1896 Female, age 85, right hemisphere 29.1
Anterior cingulate cortex, supragenual-ventral
nTPM: 30.2
1761 Male, age 74, left hemisphere 36.9
2479 Female, age 67, right hemisphere 32.9
1950 Female, age 85, right hemisphere 30.7
1755 Female, age 94, right hemisphere 28.2
2538 Male, age 75, left hemisphere 22.5
Anterior insular cortex, dorsal
nTPM: 28.5
2235 Female, age 91, right hemisphere 31.0
2001 Male, age 76, right hemisphere 29.7
2670 Male, age 75, left hemisphere 26.7
2506 Female, age 94, right hemisphere 26.6
Anterior insular cortex, ventral
nTPM: 27.1
2262 Female, age 67, right hemisphere 29.9
2507 Female, age 94, left hemisphere 27.6
1852 Male, age 76, left hemisphere 27.5
1925 Female, age 91, left hemisphere 27.4
2757 Male, age 61, right hemisphere 25.3
2596 Male, age 75, left hemisphere 24.7
Area parastriata, inferior
nTPM: 29.3
2234 Male, age 75, left hemisphere 34.1
2509 Female, age 94, left hemisphere 32.7
2421 Female, age 91, left hemisphere 30.3
1758 Female, age 72, right hemisphere 29.0
2268 Male, age 61, right hemisphere 26.9
1789 Male, age 76, right hemisphere 26.7
1760 Female, age 67, left hemisphere 25.6
Area parastriata, parietal
nTPM: 30.7
1785 Male, age 76, right hemisphere 34.4
2420 Male, age 75, left hemisphere 32.6
2680 Female, age 94, right hemisphere 32.0
2233 Male, age 61, right hemisphere 29.2
2236 Female, age 91, left hemisphere 25.6
Area parastriata, superior
nTPM: 30.2
2435 Male, age 61, left hemisphere 38.7
2604 Female, age 94, right hemisphere 34.0
2419 Male, age 75, right hemisphere 30.9
1773 Female, age 91, left hemisphere 28.5
2684 Female, age 67, left hemisphere 27.6
2881 Male, age 76, left hemisphere 21.5
Area parastriata, temporal
nTPM: 28.9
1804 Male, age 76, right hemisphere 31.5
2424 Female, age 67, left hemisphere 31.5
2267 Male, age 61, right hemisphere 28.4
2471 Male, age 75, left hemisphere 27.6
2681 Female, age 94, right hemisphere 25.7
Area striata
nTPM: 29.9
2002 Female, age 91, right hemisphere 32.6
2427 Female, age 91, left hemisphere 32.4
2679 Female, age 94, right hemisphere 30.2
2417 Male, age 61, right hemisphere 29.3
1753 Female, age 72, right hemisphere 28.3
1884 Male, age 76, left hemisphere 26.6
Claustrum
nTPM: 30.7
2645 Female, age 72, unknown 34.5
2198 Male, age 80, both hemispheres 33.1
2568 Male, age 61, both hemispheres 32.3
2292 Female, age 85, both hemispheres 30.8
1956 Male, age 74, unknown 30.7
2284 Female, age 91, both hemispheres 30.3
2196 Female, age 79, unknown 29.1
2491 Male, age 75, both hemispheres 27.9
2392 Female, age 94, both hemispheres 27.3
Frontal eye field
nTPM: 26.7
2441 Male, age 75, left hemisphere 29.0
2147 Male, age 61, left hemisphere 27.2
2543 Male, age 74, left hemisphere 25.7
2761 Female, age 94, left hemisphere 25.0
Frontal operculum
nTPM: 27.9
2030 Male, age 61, right hemisphere 30.8
2348 Male, age 75, left hemisphere 27.9
2781 Female, age 85, right hemisphere 24.9
Fusiform gyrus
nTPM: 28.7
2112 Male, age 80, both hemispheres 32.5
2784 Female, age 85, left hemisphere 31.5
2074 Female, age 91, left hemisphere 31.4
1807 Male, age 76, left hemisphere 31.1
2617 Female, age 94, left hemisphere 28.3
2431 Male, age 75, right hemisphere 24.8
2433 Female, age 72, left hemisphere 21.6
Inferior frontal gyrus, opercular
nTPM: 28.4
2874 Female, age 85, right hemisphere 33.2
2869 Male, age 74, left hemisphere 31.3
2865 Male, age 61, left hemisphere 28.3
2875 Female, age 67, left hemisphere 28.2
2867 Male, age 75, left hemisphere 28.1
2873 Female, age 85, left hemisphere 28.1
2866 Male, age 61, right hemisphere 27.8
2871 Female, age 94, left hemisphere 27.8
2868 Male, age 75, right hemisphere 26.8
2872 Female, age 94, right hemisphere 24.6
Inferior parietal lobule
nTPM: 30.9
2606 Female, age 67, right hemisphere 33.3
2418 Male, age 75, left hemisphere 32.1
2876 Male, age 76, right hemisphere 31.3
2599 Female, age 94, left hemisphere 27.0
Inferior temporal gyrus
nTPM: 28.0
1965 Female, age 91, left hemisphere 31.7
1808 Male, age 76, left hemisphere 31.2
1970 Female, age 85, right hemisphere 30.6
2430 Male, age 75, right hemisphere 30.5
1880 Male, age 80, right hemisphere 25.5
2689 Female, age 94, right hemisphere 18.8
Intraparietal deep sulcus
nTPM: 30.4
2600 Female, age 94, right hemisphere 41.7
2102 Female, age 91, left hemisphere 33.3
2607 Female, age 67, right hemisphere 32.9
2230 Male, age 61, right hemisphere 26.9
2669 Male, age 75, left hemisphere 24.0
2798 Male, age 76, left hemisphere 23.9
Lingual gyrus
nTPM: 27.1
2073 Female, age 85, left hemisphere 29.6
2688 Male, age 75, right hemisphere 28.4
2618 Female, age 94, left hemisphere 27.3
2838 Male, age 80, right hemisphere 26.7
1893 Male, age 76, left hemisphere 23.4
Middle cingulate cortex
nTPM: 31.1
2640 Female, age 94, right hemisphere 34.4
2028 Female, age 85, left hemisphere 32.3
2633 Male, age 74, left hemisphere 30.3
2539 Male, age 75, left hemisphere 29.6
2357 Female, age 67, right hemisphere 29.0
Middle temporal gyrus
nTPM: 29.0
1799 Male, age 76, left hemisphere 32.9
1819 Male, age 80, right hemisphere 30.4
2611 Male, age 75, right hemisphere 29.1
2034 Female, age 91, right hemisphere 26.8
2616 Female, age 94, left hemisphere 25.8
Occipital cortex
nTPM: 30.3
2426 Male, age 75, midline 33.7
2677 Female, age 67, right hemisphere 31.9
2470 Male, age 75, right hemisphere 31.0
2608 Female, age 67, both hemispheres 30.1
1842 Male, age 76, right hemisphere 25.1
Olfactory area
nTPM: 29.6
1805 Female, age 85, right hemisphere 36.2
2542 Male, age 74, left hemisphere 30.4
2756 Female, age 67, right hemisphere 29.7
2222 Female, age 67, right hemisphere 28.1
2440 Male, age 75, left hemisphere 26.6
2352 Female, age 94, right hemisphere 26.4
Olfactory tubercle
nTPM: 26.6
1846 Male, age 80, right hemisphere 30.6
1998 Female, age 91, both hemispheres 29.2
2856 Male, age 75, right hemisphere 24.8
2487 Female, age 94, left hemisphere 21.9
Orbitofrontal gyrus, anterior
nTPM: 31.9
2864 Female, age 67, left hemisphere 39.5
2862 Female, age 85, left hemisphere 29.1
2863 Female, age 85, right hemisphere 27.2
Paracentral lobule, anterior
nTPM: 29.2
1776 Female, age 85, right hemisphere 33.0
2474 Male, age 74, left hemisphere 31.9
2340 Female, age 67, right hemisphere 30.6
2638 Female, age 94, right hemisphere 29.1
1754 Male, age 75, left hemisphere 25.9
1926 Male, age 61, left hemisphere 24.5
Paracentral lobule, posterior
nTPM: 30.3
2551 Female, age 94, right hemisphere 32.3
1775 Female, age 85, right hemisphere 31.9
2345 Male, age 61, left hemisphere 31.1
1764 Male, age 74, right hemisphere 31.0
2446 Male, age 75, left hemisphere 25.1
Parietal operculum
nTPM: 26.8
1763 Male, age 74, left hemisphere 29.6
2356 Female, age 67, right hemisphere 27.5
2552 Female, age 94, right hemisphere 27.5
2719 Male, age 75, left hemisphere 22.7
Parieto-insular cortex
nTPM: 26.8
1976 Female, age 91, right hemisphere 33.9
2508 Female, age 94, right hemisphere 27.0
2831 Male, age 76, right hemisphere 25.8
2232 Male, age 61, right hemisphere 24.2
2671 Male, age 75, left hemisphere 22.9
Parieto-occipital transitional area
nTPM: 30.1
2683 Female, age 67, left hemisphere 35.4
2468 Male, age 75, left hemisphere 30.6
2674 Female, age 94, right hemisphere 30.6
1784 Male, age 76, right hemisphere 29.3
2270 Male, age 61, right hemisphere 24.5
Piriform cortex
nTPM: 38.2
2153 Female, age 85, left hemisphere 39.1
2347 Male, age 75, right hemisphere 37.2
Postcentral gyrus
nTPM: 34.4
2533 Male, age 75, right hemisphere 34.4
Postcentral gyrus, dorsal
nTPM: 31.6
2477 Female, age 94, right hemisphere 40.9
1836 Female, age 85, right hemisphere 34.4
2339 Female, age 67, right hemisphere 30.3
2350 Male, age 75, left hemisphere 29.3
2151 Male, age 61, left hemisphere 28.0
2544 Male, age 74, left hemisphere 26.7
Postcentral gyrus, middle
nTPM: 29.3
2444 Male, age 75, left hemisphere 33.7
1897 Female, age 85, right hemisphere 31.8
2146 Female, age 67, right hemisphere 29.4
2248 Male, age 61, left hemisphere 27.7
2545 Male, age 74, left hemisphere 23.7
Postcentral gyrus, ventral
nTPM: 25.8
2445 Male, age 75, left hemisphere 28.0
2024 Female, age 85, right hemisphere 25.5
2836 Female, age 94, right hemisphere 23.9
Posterior cingulate cortex
nTPM: 31.0
1759 Male, age 74, right hemisphere 32.1
2553 Female, age 94, right hemisphere 31.5
2473 Male, age 75, left hemisphere 29.3
Posterior cingulate cortex, dorsal
nTPM: 32.8
2641 Female, age 94, right hemisphere 38.3
2343 Male, age 61, left hemisphere 36.4
2556 Female, age 67, right hemisphere 32.8
2634 Male, age 74, left hemisphere 31.8
2540 Male, age 75, right hemisphere 30.8
2076 Female, age 85, right hemisphere 27.0
Posterior cingulate cortex, ventral
nTPM: 29.2
2448 Female, age 67, right hemisphere 32.5
1994 Female, age 85, right hemisphere 30.2
2635 Male, age 74, left hemisphere 28.8
1762 Female, age 94, right hemisphere 28.6
2541 Male, age 75, right hemisphere 27.9
2346 Male, age 61, left hemisphere 27.1
Posterior insular cortex
nTPM: 26.0
2511 Female, age 67, right hemisphere 29.1
2597 Male, age 75, left hemisphere 26.7
2832 Female, age 91, right hemisphere 26.5
2603 Female, age 94, left hemisphere 25.4
2231 Male, age 61, left hemisphere 24.7
1823 Male, age 76, right hemisphere 23.9
Precentral gyrus
nTPM: 29.5
2557 Male, age 75, right hemisphere 29.5
Precentral gyrus, dorsal
nTPM: 31.1
2476 Female, age 94, right hemisphere 36.4
2354 Female, age 67, right hemisphere 32.1
2442 Male, age 75, left hemisphere 29.9
1756 Male, age 74, left hemisphere 26.0
Precentral gyrus, middle
nTPM: 30.1
2475 Male, age 74, right hemisphere 33.0
1969 Female, age 67, right hemisphere 32.2
2443 Male, age 75, left hemisphere 30.4
1909 Male, age 61, left hemisphere 29.8
2549 Female, age 94, right hemisphere 25.3
Precentral gyrus, ventral
nTPM: 26.4
2662 Female, age 67, right hemisphere 29.9
2630 Male, age 75, left hemisphere 26.9
2550 Female, age 94, right hemisphere 24.9
2678 Male, age 74, left hemisphere 24.0
Precuneus
nTPM: 28.6
1782 Male, age 76, right hemisphere 33.7
2467 Male, age 75, right hemisphere 28.5
2673 Female, age 94, right hemisphere 28.4
1780 Female, age 91, right hemisphere 27.7
2510 Female, age 67, right hemisphere 27.6
2594 Male, age 61, left hemisphere 25.5
Premotor cortex, dorsal
nTPM: 30.1
2631 Male, age 74, left hemisphere 37.0
2554 Female, age 67, right hemisphere 31.8
2536 Male, age 75, left hemisphere 30.2
1878 Female, age 85, right hemisphere 27.4
2027 Male, age 61, left hemisphere 24.3
Premotor cortex, ventral
nTPM: 27.8
2637 Female, age 94, right hemisphere 32.1
1881 Female, age 85, right hemisphere 28.6
1757 Male, age 74, left hemisphere 27.7
2349 Male, age 75, left hemisphere 27.1
1779 Male, age 61, left hemisphere 25.8
1777 Female, age 67, left hemisphere 25.7
Retrosplenial cortex
nTPM: 27.4
1914 Male, age 76, right hemisphere 31.5
2675 Female, age 94, left hemisphere 28.2
1951 Male, age 61, right hemisphere 22.4
Subcentral gyrus, S2
nTPM: 24.7
1964 Female, age 85, right hemisphere 28.8
2072 Male, age 61, left hemisphere 26.4
2555 Female, age 67, right hemisphere 26.0
2762 Male, age 74, left hemisphere 22.9
2351 Male, age 75, left hemisphere 22.4
2839 Female, age 94, right hemisphere 21.4
Superior parietal lobule
nTPM: 30.6
2605 Female, age 67, right hemisphere 36.3
1800 Male, age 76, right hemisphere 36.2
1992 Female, age 91, right hemisphere 32.7
2229 Male, age 61, right hemisphere 24.6
2672 Female, age 94, right hemisphere 23.1
Superior temporal gyrus
nTPM: 27.7
2025 Male, age 80, right hemisphere 35.3
1844 Female, age 91, left hemisphere 30.4
2615 Female, age 94, left hemisphere 26.6
2687 Male, age 75, right hemisphere 23.4
1843 Male, age 76, left hemisphere 22.8
Supplementary motor cortex
nTPM: 29.3
2548 Female, age 94, right hemisphere 33.6
2537 Male, age 75, left hemisphere 28.6
2632 Male, age 74, left hemisphere 27.8
1993 Male, age 61, left hemisphere 27.1
Supramarginal gyrus
nTPM: 27.5
1991 Female, age 91, right hemisphere 30.8
2601 Female, age 94, left hemisphere 29.4
2513 Female, age 72, left hemisphere 27.9
1798 Male, age 76, right hemisphere 26.2
2415 Male, age 61, left hemisphere 23.2
Temporal pole
nTPM: 30.0
2518 Male, age 75, right hemisphere 34.2
1853 Female, age 85, right hemisphere 32.2
2612 Female, age 94, left hemisphere 30.6
1832 Female, age 91, left hemisphere 30.3
1826 Male, age 76, right hemisphere 22.9
Temporo-insular cortex, parainsular gyrus
nTPM: 30.6
2512 Female, age 67, right hemisphere 36.0
2598 Male, age 75, left hemisphere 31.1
1802 Male, age 76, left hemisphere 30.4
2264 Female, age 91, right hemisphere 29.9
2676 Female, age 94, right hemisphere 28.7
2416 Male, age 61, right hemisphere 27.1
Temporo-occipital transitional zone
nTPM: 28.3
1793 Male, age 80, right hemisphere 33.3
2251 Female, age 85, right hemisphere 30.3
1900 Male, age 76, left hemisphere 21.3
Transversal temporal gyrus, anterior
nTPM: 26.7
1910 Male, age 80, right hemisphere 30.0
2522 Female, age 94, left hemisphere 27.2
1809 Male, age 76, right hemisphere 26.8
1888 Female, age 91, left hemisphere 26.2
2610 Male, age 75, right hemisphere 23.1
Transversal temporal gyrus, posterior
nTPM: 26.9
1967 Female, age 91, right hemisphere 30.2
2520 Male, age 75, right hemisphere 27.6
2614 Female, age 94, left hemisphere 26.4
2833 Male, age 80, right hemisphere 25.2
1922 Male, age 76, left hemisphere 24.9

CEREBRAL CORTEX - HPA PFC Brain RNA-seq
Max nTPM 43.8
Sample id Sample description nTPM
Anterior cingulate gyrus, pregenual-dorsal
nTPM: 43.1
1516 Female, age 85, left hemisphere 57.3
1514 Male, age 74, right hemisphere 54.9
1518 Female, age 67, right hemisphere 47.1
1517 Female, age 67, left hemisphere 45.7
1513 Male, age 74, left hemisphere 44.2
1511 Male, age 61, right hemisphere 39.0
1510 Male, age 61, left hemisphere 34.6
1515 Female, age 94, right hemisphere 34.4
1512 Male, age 75, left hemisphere 30.9
Anterior cingulate gyrus, pregenual-ventral
nTPM: 43.8
1521 Male, age 74, left hemisphere 59.7
1522 Male, age 74, right hemisphere 45.0
1523 Female, age 67, left hemisphere 42.0
1519 Male, age 61, left hemisphere 39.9
1520 Male, age 75, right hemisphere 32.5
Anterior cingulate gyrus, subgenual
nTPM: 41.7
1527 Male, age 74, left hemisphere 47.8
1528 Male, age 74, right hemisphere 45.7
1529 Female, age 85, left hemisphere 45.6
1526 Male, age 75, right hemisphere 43.2
1525 Male, age 75, left hemisphere 38.5
1530 Female, age 67, right hemisphere 37.4
1524 Male, age 61, left hemisphere 33.9
Dorsolateral prefrontal cortex
nTPM: 34.3
1450 Female, age 67, right hemisphere 43.5
1446 Male, age 74, right hemisphere 41.9
1449 Female, age 85, right hemisphere 39.1
1447 Female, age 94, left hemisphere 31.4
1444 Male, age 75, left hemisphere 29.2
1445 Male, age 75, right hemisphere 27.7
1448 Female, age 94, right hemisphere 27.2
Dorsomedial prefrontal cortex
nTPM: 35.7
1442 Male, age 75, right hemisphere 59.8
1443 Female, age 67, right hemisphere 38.1
1441 Male, age 75, left hemisphere 36.4
1439 Male, age 61, left hemisphere 22.8
1440 Male, age 61, right hemisphere 21.3
Frontal cortex
nTPM: 31.1
1574 Male, age 75, left hemisphere 38.0
1581 Female, age 85, right hemisphere 37.4
1580 Female, age 85, left hemisphere 35.3
1577 Male, age 74, right hemisphere 34.2
1575 Male, age 75, right hemisphere 33.1
1582 Female, age 67, left hemisphere 31.6
1573 Male, age 61, right hemisphere 30.7
1579 Female, age 94, right hemisphere 30.6
1576 Male, age 74, left hemisphere 28.3
1578 Female, age 94, left hemisphere 27.0
1583 Female, age 67, right hemisphere 26.6
1572 Male, age 61, left hemisphere 20.4
Frontomarginal cortex
nTPM: 29.4
1468 Male, age 74, left hemisphere 41.2
1472 Female, age 67, left hemisphere 37.7
1469 Female, age 94, left hemisphere 35.4
1473 Female, age 67, right hemisphere 31.5
1470 Female, age 94, right hemisphere 27.5
1471 Female, age 85, left hemisphere 27.4
1466 Male, age 61, right hemisphere 22.8
1467 Male, age 75, right hemisphere 22.6
1465 Male, age 61, left hemisphere 18.7
Frontopolar cortex
nTPM: 27.4
1463 Female, age 67, left hemisphere 40.7
1464 Female, age 67, right hemisphere 31.2
1462 Female, age 94, left hemisphere 29.0
1460 Male, age 75, left hemisphere 25.2
1459 Male, age 61, right hemisphere 24.4
1461 Male, age 75, right hemisphere 23.4
1458 Male, age 61, left hemisphere 18.0
Gyrus rectus
nTPM: 26.8
1480 Female, age 85, left hemisphere 37.0
1478 Female, age 94, left hemisphere 36.0
1477 Male, age 75, right hemisphere 28.1
1479 Female, age 94, right hemisphere 26.1
1481 Female, age 67, left hemisphere 26.1
1476 Male, age 75, left hemisphere 22.0
1474 Male, age 61, left hemisphere 20.8
1475 Male, age 61, right hemisphere 18.4
Inferior frontal gyrus, orbital
nTPM: 39.5
1504 Male, age 74, left hemisphere 51.2
1508 Female, age 85, right hemisphere 44.6
1505 Male, age 74, right hemisphere 42.9
1507 Female, age 85, left hemisphere 41.9
1502 Male, age 75, left hemisphere 41.8
1509 Female, age 67, right hemisphere 40.3
1506 Female, age 94, left hemisphere 39.0
1503 Male, age 75, right hemisphere 38.1
1500 Male, age 61, left hemisphere 31.1
1501 Male, age 61, right hemisphere 24.1
Inferior frontal gyrus, triangular
nTPM: 36.6
1547 Female, age 85, left hemisphere 44.0
1545 Male, age 74, right hemisphere 42.8
1544 Male, age 75, right hemisphere 40.2
1543 Male, age 61, right hemisphere 37.2
1546 Female, age 94, right hemisphere 36.9
1549 Female, age 67, left hemisphere 36.2
1542 Male, age 61, left hemisphere 27.9
1548 Female, age 85, right hemisphere 27.5
Orbitofrontal gyrus, lateral
nTPM: 40.1
1497 Female, age 85, left hemisphere 57.8
1499 Female, age 67, right hemisphere 44.7
1498 Female, age 85, right hemisphere 41.4
1496 Female, age 94, right hemisphere 37.3
1495 Female, age 94, left hemisphere 37.2
1494 Male, age 75, left hemisphere 32.4
1493 Male, age 61, right hemisphere 29.5
Orbitofrontal gyrus, medial
nTPM: 27.1
1489 Female, age 85, left hemisphere 36.2
1485 Male, age 74, left hemisphere 31.7
1491 Female, age 67, left hemisphere 31.2
1492 Female, age 67, right hemisphere 29.6
1490 Female, age 85, right hemisphere 28.9
1486 Male, age 74, right hemisphere 28.6
1488 Female, age 94, right hemisphere 24.3
1482 Male, age 61, left hemisphere 22.9
1487 Female, age 94, left hemisphere 21.9
1483 Male, age 75, left hemisphere 21.7
1484 Male, age 75, right hemisphere 20.9
Orbitofrontal gyrus, posterior
nTPM: 41.4
1538 Female, age 85, left hemisphere 50.4
1541 Female, age 67, right hemisphere 48.2
1539 Female, age 85, right hemisphere 46.4
1535 Male, age 74, left hemisphere 45.6
1540 Female, age 67, left hemisphere 45.0
1534 Male, age 75, right hemisphere 44.6
1536 Female, age 94, left hemisphere 43.4
1537 Female, age 94, right hemisphere 41.4
1533 Male, age 75, left hemisphere 38.1
1531 Male, age 61, left hemisphere 27.4
1532 Male, age 61, right hemisphere 25.2
Subcallosal gyrus
nTPM: 28.9
1560 Female, age 67, left hemisphere 36.7
1557 Female, age 94, right hemisphere 32.0
1552 Male, age 75, left hemisphere 31.6
1555 Male, age 74, right hemisphere 31.4
1558 Female, age 85, left hemisphere 30.8
1554 Male, age 74, left hemisphere 30.7
1561 Female, age 67, right hemisphere 28.0
1553 Male, age 75, right hemisphere 27.4
1556 Female, age 94, left hemisphere 26.2
1551 Male, age 61, right hemisphere 25.2
1559 Female, age 85, right hemisphere 24.0
1550 Male, age 61, left hemisphere 22.6
Superior frontal gyrus
nTPM: 31.4
1570 Female, age 85, right hemisphere 41.3
1566 Male, age 74, right hemisphere 35.4
1569 Female, age 85, left hemisphere 34.5
1565 Male, age 75, right hemisphere 33.3
1571 Female, age 67, right hemisphere 31.4
1567 Female, age 94, left hemisphere 30.0
1562 Male, age 61, left hemisphere 29.8
1564 Male, age 75, left hemisphere 28.9
1568 Female, age 94, right hemisphere 27.2
1563 Male, age 61, right hemisphere 21.9
Temporal cortex
nTPM: 29.8
1595 Female, age 94, right hemisphere 39.3
1593 Male, age 74, right hemisphere 36.0
1596 Female, age 85, right hemisphere 31.0
1591 Male, age 75, right hemisphere 28.4
1594 Female, age 94, left hemisphere 27.6
1592 Male, age 74, left hemisphere 26.7
1590 Male, age 61, right hemisphere 19.6
Ventrolateral prefrontal cortex
nTPM: 32.4
1455 Female, age 85, right hemisphere 40.4
1453 Male, age 74, right hemisphere 36.8
1457 Female, age 67, right hemisphere 36.3
1454 Female, age 94, left hemisphere 34.7
1456 Female, age 67, left hemisphere 27.4
1451 Male, age 75, right hemisphere 25.8
1452 Male, age 74, left hemisphere 25.3
Ventromedial prefrontal cortex
nTPM: 32.6
1436 Female, age 85, left hemisphere 52.2
1435 Female, age 94, right hemisphere 38.3
1438 Female, age 67, left hemisphere 33.2
1437 Female, age 85, right hemisphere 33.1
1432 Male, age 61, left hemisphere 27.5
1434 Male, age 75, right hemisphere 22.2
1433 Male, age 61, right hemisphere 21.3

CEREBRAL CORTEX - GTEx RNA-seqi
Average nTPM 56.8
GTEx sample id Sample description nTPM
49.355.964.426.886.20102030405060708090
Brain - Anterior cingulate cortex (BA24)
Average nTPM: 56.8
Samples: 176

Max nTPM: 90.6
Min nTPM: 26.8
Std nTPM: 12.2
Median nTPM: 55.9
GTEX-1H3VE-0011-R3a-SM-CE6SK 40-49 years, male 90.6
GTEX-13PLJ-0011-R3a-SM-5O9DT 60-69 years, female 86.2
GTEX-1J8EW-0011-R3a-SM-ARU8A 60-69 years, female 85.5
GTEX-1I1GS-0011-R3b-SM-CYPS7 60-69 years, male 84.7
GTEX-14BMV-0011-R3a-SM-5ZZU7 50-59 years, male 83.9
GTEX-1EN7A-0011-R3a-SM-9OSVT 40-49 years, male 83.7
GTEX-1JMPZ-0011-R3a-SM-EYYWX 30-39 years, male 81.9
GTEX-1KD4Q-0011-R3b-SM-EXOID 40-49 years, male 80.9
GTEX-14JG1-0011-R3a-SM-62LEC 40-49 years, male 79.9
GTEX-139TT-0011-R3b-SM-5K7VL 60-69 years, male 79.5
GTEX-16XZZ-0011-R3a-SM-7IGLH 60-69 years, male 79.4
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43.849.656.126.371.40102030405060708090100
Brain - Cortex
Average nTPM: 50.9
Samples: 255

Max nTPM: 105.1
Min nTPM: 24.1
Std nTPM: 10.5
Median nTPM: 49.6
GTEX-1JJE9-2926-SM-CY8HV 70-79 years, male 105.1
GTEX-1HBPM-2926-SM-CL54E 60-69 years, female 88.7
GTEX-1CAV2-2726-SM-7IGNN 40-49 years, female 81.9
GTEX-1NV5F-3226-SM-EXUSL 60-69 years, female 80.1
GTEX-1H3VE-2726-SM-9WPP3 40-49 years, male 78.2
GTEX-1C64N-3026-SM-7MGVU 50-59 years, male 78.0
GTEX-1IOXB-3126-SM-CKZO1 50-59 years, male 76.6
GTEX-15UF6-3026-SM-7KUKL 70-79 years, female 76.2
GTEX-1M4P7-2726-SM-E9TJQ 60-69 years, male 71.4
GTEX-1GZHY-3126-SM-9QEHH 50-59 years, female 71.3
GTEX-17MF6-2926-SM-7LTAW 40-49 years, male 71.2
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42.448.955.724.875.30102030405060708090
Brain - Frontal Cortex (BA9)
Average nTPM: 50.0
Samples: 209

Max nTPM: 94.8
Min nTPM: 19.8
Std nTPM: 11.8
Median nTPM: 48.9
GTEX-131XW-0011-R10a-SM-5DUVA 50-59 years, female 94.8
GTEX-1C6VQ-0011-R10b-SM-7P8Q1 50-59 years, male 89.7
GTEX-1HBPM-0011-R10a-SM-CJI3Q 60-69 years, female 84.0
GTEX-1477Z-0011-R10b-SM-5S2RF 60-69 years, male 78.0
GTEX-1GF9V-0011-R10b-SM-CKZNP 60-69 years, male 76.9
GTEX-1I1CD-0011-R10b-SM-CJI3W 60-69 years, female 76.7
GTEX-13O3O-0011-R10a-SM-5LUA9 60-69 years, female 76.6
GTEX-1H4P4-0011-R10b-SM-CE6SG 50-59 years, male 75.3
GTEX-ZV68-0011-R10a-SM-51MT7 50-59 years, female 73.7
GTEX-139TS-0011-R10a-SM-5K7TU 60-69 years, male 73.6
GTEX-14PJO-0011-R10a-SM-686ZS 60-69 years, male 72.5
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CEREBRAL CORTEX - FANTOM5 CAGEi
Max Scaled Tags Per Million 53.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Occipital cortex
Scaled Tags Per Million: 48.0
FF:10163-103B1 76 years, female 48.0
Postcentral gyrus
Scaled Tags Per Million: 49.9
FF:10032-101E5 44-52 years, mixed 49.9
Frontal lobe
Scaled Tags Per Million: 40.1
FF:10040-101F4 32-61 years, mixed 40.1
Insula
Scaled Tags Per Million: 41.8
FF:10039-101F3 20-68 years, mixed 41.8
Medial frontal gyrus
Scaled Tags Per Million: 46.5
FF:10150-102I6 76 years, female 46.5
Medial temporal gyrus
Scaled Tags Per Million: 44.8
FF:10156-103A3 76 years, female 47.6
FF:10183-103D3 60 years, female 42.0
Occipital lobe
Scaled Tags Per Million: 36.8
FF:10076-102A4 27 years, male 36.8
Occipital pole
Scaled Tags Per Million: 53.7
FF:10036-101E9 22-68 years, mixed 53.7
Paracentral gyrus
Scaled Tags Per Million: 42.9
FF:10035-101E8 22-69 years, mixed 42.9
Parietal lobe
Scaled Tags Per Million: 46.2
FF:10171-103B9 60 years, female 50.5
FF:10034-101E7 35-89 years, mixed 46.8
FF:10157-103A4 76 years, female 41.2
Temporal lobe
Scaled Tags Per Million: 49.3
FF:10031-101E4 32-61 years, mixed 49.3

CEREBRAL CORTEX - Pig RNA-seqi
Average nTPM 20.5
Pig sample Sample description nTPM
16.617.619.114.217.80246810121416182022
 		Occipital cortex
nTPM: 18.1
Samples: 4

Max nTPM: 22.8
Min nTPM: 14.2
Sample A Female 17.8
Sample B Female 14.2
Sample C Male 22.8
Sample D Male 17.4
14.416.418.413.119.8024681012141618
 		Retrosplenial cortex
nTPM: 16.4
Samples: 4

Max nTPM: 19.8
Min nTPM: 13.1
Sample A Female 18.0
Sample B Female 13.1
Sample C Male 19.8
Sample D Male 14.8
13.515.918.310.321.102468101214161820
 		Cingulate cortex
nTPM: 15.8
Samples: 4

Max nTPM: 21.1
Min nTPM: 10.3
Sample A Female 21.1
Sample B Female 10.3
Sample C Male 17.3
Sample D Male 14.6
11.913.615.911.518.0024681012141618
 		Insular cortex
nTPM: 14.2
Samples: 4

Max nTPM: 18.0
Min nTPM: 11.5
Sample A Female 18.0
Sample B Female 11.5
Sample C Male 15.2
Sample D Male 12.0
16.017.319.115.721.402468101214161820
 		Motor cortex
nTPM: 17.9
Samples: 4

Max nTPM: 21.4
Min nTPM: 15.7
Sample A Female 18.4
Sample B Female 15.7
Sample C Male 21.4
Sample D Male 16.1
Prefrontal cortex
nTPM: 16.2
Samples: 4

Max nTPM: 16.8
Min nTPM: 15.3
Sample A Female 16.8
Sample B Female 16.0
Sample C Male 16.5
Sample D Male 15.3
19.421.722.317.022.80246810121416182022
 		Somatosensory cortex
nTPM: 20.5
Samples: 3

Max nTPM: 22.8
Min nTPM: 17.0
Sample B Female 17.0
Sample C Male 21.7
Sample D Male 22.8
15.516.217.113.519.5024681012141618
 		Temporal cortex
nTPM: 16.4
Samples: 4

Max nTPM: 19.5
Min nTPM: 13.5
Sample A Female 16.3
Sample B Female 13.5
Sample C Male 19.5
Sample D Male 16.1

CEREBRAL CORTEX - Mouse RNA-seqi
Average nTPM 68.5
Mouse sample Sample description nTPM
59.763.668.559.272.0010203040506070
 		Occipital cortex
nTPM: 64.6
Samples: 4

Max nTPM: 72.0
Min nTPM: 59.2
Sample A Male 67.3
Sample B Male 59.9
Sample C Female 59.2
Sample D Female 72.0
61.964.566.655.971.4010203040506070
 		Frontal cortex
nTPM: 64.1
Samples: 4

Max nTPM: 71.4
Min nTPM: 55.9
Sample A Male 55.9
Sample B Male 71.4
Sample C Female 63.9
Sample D Female 65.0
67.367.969.066.871.3010203040506070
 		Retrosplenial and cingulate cortex
nTPM: 68.5
Samples: 4

Max nTPM: 71.3
Min nTPM: 66.8
Sample A Male 71.3
Sample B Male 67.5
Sample C Female 68.3
Sample D Female 66.8
62.063.966.760.570.9010203040506070
 		Somatosensory cortex
nTPM: 64.8
Samples: 4

Max nTPM: 70.9
Min nTPM: 60.5
Sample A Male 70.9
Sample B Male 65.3
Sample C Female 62.5
Sample D Female 60.5

CEREBRAL CORTEX - Allen Mouse ISHi
Max Expression energy 0.6
Allen experiment id Experiment description Expression energy
Cerebral cortex
Expression energy: 0.6
100144110 Antisense, RP_110407_03_A09, Mouse strain C57BL/6J (56 days, male) 0.6

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