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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA011740
Smooth muscle and endothelial cells exhibited moderate cytoplasmic positivity. Moderate membranous staining was exhibited in pneumocytes. A subset of cells in seminal vesicle displayed strong nuclear staining. Remaining normal tissues were weakly stained or mostly negative.
HPA014290
Respiratory epithelia, renal tubules and salivary glands showed strong membranous positivity. Neurons exhibited strong cytoplasmic staining. Glial cells, fallopian tubes, squamous epithelium, decidual cells, stomach and endometrium were moderately stained. Other normal tissues were weakly stained or negative.
CAB068189
Heart, skeletal and smooth muscle cells, placental trophoblastic cells and endothelial cells showed moderate to strong cytoplasmic positivity. Remaining normal cell types were in general negative.
CAB068190
Trophoblastic cells, stomach and myocytes showed strong cytoplasmic staining. Endoethelial cells were discintly stained. Gall bladder, renal tubules, smooth muscle and thyroid displayed moderate positivity. Fallopian tube exhibited additional membranous staining. Remaining normal cell types were weakly stained or negative.
The Human Protein Atlas project is funded
