CEREBRAL CORTEX - Expression summary
Protein expression
Cerebral cortexi
h
m
l
n
Endothelial cells: Not detected
Glial cells: Not detected
Neuronal cells: Medium
Neuropil: Medium
RNA expressioni
Consensus:54.0 nTPM
HPA:13.2 nTPM
HPA Brain:40.9 nTPM
HPA PFC Brain:47.7 nTPM
GTEx:54.0 nTPM
FANTOM5:43.7 Scaled Tags Per Million
Pig:15.0 nTPM
Mouse:42.1 nTPM
Allen mouse:2.4 Expression energy

CEREBRAL CORTEX - Antibody stainingi
Antibody HPA041113
Endothelial cells Not detected
Glial cells Not detected
Neuronal cells Medium
Neuropil Medium



CEREBRAL CORTEX - HPA RNA-seqi
Average nTPM 13.2
N/A
Male, age 5
Cerebral cortex sample 48
nTPM: 20.1
overview
Female, age 40
Cerebral cortex sample 105
nTPM: 9
Cell types%
Neuronal cells:
35

Glial cells and endothelial cells:
65
overview
Male, age 70
Cerebral cortex sample 106
nTPM: 10.6
Cell types%
Neuronal cells:
35

Glial cells and endothelial cells:
65

CEREBRAL CORTEX - HPA Brain RNA-seq
Max nTPM 40.9
Sample id Sample description nTPM
Angular gyrus
nTPM: 31.3
1790 Male, age 76, right hemisphere 39.6
2103 Male, age 75, left hemisphere 38.0
2260 Female, age 72, left hemisphere 34.0
2221 Female, age 67, right hemisphere 33.1
1866 Male, age 76, both hemispheres 31.1
2265 Female, age 91, left hemisphere 30.2
2602 Female, age 94, right hemisphere 24.9
2722 Male, age 61, left hemisphere 19.3
Anterior cingulate cortex, supragenual-dorsal
nTPM: 32.0
2547 Male, age 74, left hemisphere 37.7
2478 Female, age 67, right hemisphere 32.2
1896 Female, age 85, right hemisphere 31.1
2472 Male, age 75, left hemisphere 30.2
2342 Female, age 94, right hemisphere 28.6
Anterior cingulate cortex, supragenual-ventral
nTPM: 31.4
1950 Female, age 85, right hemisphere 35.5
2538 Male, age 75, left hemisphere 31.7
2479 Female, age 67, right hemisphere 31.3
1755 Female, age 94, right hemisphere 31.0
1761 Male, age 74, left hemisphere 27.5
Anterior insular cortex, dorsal
nTPM: 27.2
2670 Male, age 75, left hemisphere 29.8
2506 Female, age 94, right hemisphere 28.2
2235 Female, age 91, right hemisphere 27.3
2001 Male, age 76, right hemisphere 23.4
Anterior insular cortex, ventral
nTPM: 33.0
2757 Male, age 61, right hemisphere 37.9
1925 Female, age 91, left hemisphere 37.0
1852 Male, age 76, left hemisphere 33.6
2507 Female, age 94, left hemisphere 31.3
2262 Female, age 67, right hemisphere 30.8
2596 Male, age 75, left hemisphere 27.7
Area parastriata, inferior
nTPM: 29.6
1789 Male, age 76, right hemisphere 41.7
2509 Female, age 94, left hemisphere 39.6
2234 Male, age 75, left hemisphere 32.9
2268 Male, age 61, right hemisphere 28.0
1758 Female, age 72, right hemisphere 22.7
1760 Female, age 67, left hemisphere 22.1
2421 Female, age 91, left hemisphere 20.4
Area parastriata, parietal
nTPM: 31.6
1785 Male, age 76, right hemisphere 38.5
2420 Male, age 75, left hemisphere 36.7
2233 Male, age 61, right hemisphere 30.6
2236 Female, age 91, left hemisphere 27.3
2680 Female, age 94, right hemisphere 25.0
Area parastriata, superior
nTPM: 32.9
2881 Male, age 76, left hemisphere 40.0
2435 Male, age 61, left hemisphere 37.7
2604 Female, age 94, right hemisphere 36.3
2684 Female, age 67, left hemisphere 31.1
2419 Male, age 75, right hemisphere 29.6
1773 Female, age 91, left hemisphere 22.9
Area parastriata, temporal
nTPM: 30.4
1804 Male, age 76, right hemisphere 36.8
2424 Female, age 67, left hemisphere 35.3
2267 Male, age 61, right hemisphere 29.8
2471 Male, age 75, left hemisphere 28.5
2681 Female, age 94, right hemisphere 21.8
Area striata
nTPM: 27.4
2002 Female, age 91, right hemisphere 42.1
1884 Male, age 76, left hemisphere 30.6
2679 Female, age 94, right hemisphere 29.3
2427 Female, age 91, left hemisphere 23.3
1753 Female, age 72, right hemisphere 21.5
2417 Male, age 61, right hemisphere 17.6
Claustrum
nTPM: 35.0
2491 Male, age 75, both hemispheres 44.6
2198 Male, age 80, both hemispheres 41.3
2284 Female, age 91, both hemispheres 36.4
2568 Male, age 61, both hemispheres 35.4
2645 Female, age 72, unknown 33.8
2292 Female, age 85, both hemispheres 33.5
1956 Male, age 74, unknown 32.9
2196 Female, age 79, unknown 31.1
2392 Female, age 94, both hemispheres 25.8
Frontal eye field
nTPM: 26.4
2543 Male, age 74, left hemisphere 30.5
2147 Male, age 61, left hemisphere 29.4
2441 Male, age 75, left hemisphere 25.8
2761 Female, age 94, left hemisphere 20.0
Frontal operculum
nTPM: 32.4
2030 Male, age 61, right hemisphere 39.6
2781 Female, age 85, right hemisphere 31.6
2348 Male, age 75, left hemisphere 26.0
Fusiform gyrus
nTPM: 33.8
2074 Female, age 91, left hemisphere 44.0
2784 Female, age 85, left hemisphere 38.9
1807 Male, age 76, left hemisphere 36.2
2112 Male, age 80, both hemispheres 35.5
2431 Male, age 75, right hemisphere 31.7
2617 Female, age 94, left hemisphere 28.5
2433 Female, age 72, left hemisphere 22.1
Inferior frontal gyrus, opercular
nTPM: 24.3
2866 Male, age 61, right hemisphere 33.9
2865 Male, age 61, left hemisphere 25.9
2868 Male, age 75, right hemisphere 24.4
2869 Male, age 74, left hemisphere 24.4
2875 Female, age 67, left hemisphere 24.1
2873 Female, age 85, left hemisphere 23.6
2874 Female, age 85, right hemisphere 23.2
2871 Female, age 94, left hemisphere 21.9
2867 Male, age 75, left hemisphere 21.5
2872 Female, age 94, right hemisphere 19.9
Inferior parietal lobule
nTPM: 34.5
2876 Male, age 76, right hemisphere 49.1
2606 Female, age 67, right hemisphere 34.8
2418 Male, age 75, left hemisphere 31.0
2599 Female, age 94, left hemisphere 23.1
Inferior temporal gyrus
nTPM: 32.7
1970 Female, age 85, right hemisphere 42.8
1808 Male, age 76, left hemisphere 36.5
1965 Female, age 91, left hemisphere 36.0
1880 Male, age 80, right hemisphere 30.4
2430 Male, age 75, right hemisphere 28.0
2689 Female, age 94, right hemisphere 22.7
Intraparietal deep sulcus
nTPM: 30.8
2600 Female, age 94, right hemisphere 37.0
2102 Female, age 91, left hemisphere 36.9
2230 Male, age 61, right hemisphere 32.5
2798 Male, age 76, left hemisphere 29.8
2607 Female, age 67, right hemisphere 28.4
2669 Male, age 75, left hemisphere 20.3
Lingual gyrus
nTPM: 30.2
1893 Male, age 76, left hemisphere 33.1
2073 Female, age 85, left hemisphere 32.7
2688 Male, age 75, right hemisphere 29.3
2838 Male, age 80, right hemisphere 29.1
2618 Female, age 94, left hemisphere 26.8
Middle cingulate cortex
nTPM: 31.8
2028 Female, age 85, left hemisphere 37.8
2633 Male, age 74, left hemisphere 33.9
2640 Female, age 94, right hemisphere 31.2
2539 Male, age 75, left hemisphere 28.6
2357 Female, age 67, right hemisphere 27.4
Middle temporal gyrus
nTPM: 30.8
1799 Male, age 76, left hemisphere 37.0
1819 Male, age 80, right hemisphere 34.6
2034 Female, age 91, right hemisphere 30.7
2616 Female, age 94, left hemisphere 27.1
2611 Male, age 75, right hemisphere 24.5
Occipital cortex
nTPM: 27.7
2470 Male, age 75, right hemisphere 30.5
2426 Male, age 75, midline 30.3
2677 Female, age 67, right hemisphere 27.8
1842 Male, age 76, right hemisphere 27.0
2608 Female, age 67, both hemispheres 22.7
Olfactory area
nTPM: 34.4
2756 Female, age 67, right hemisphere 42.5
2222 Female, age 67, right hemisphere 41.7
1805 Female, age 85, right hemisphere 36.9
2542 Male, age 74, left hemisphere 34.3
2440 Male, age 75, left hemisphere 29.1
2352 Female, age 94, right hemisphere 22.2
Olfactory tubercle
nTPM: 30.6
1998 Female, age 91, both hemispheres 36.8
2487 Female, age 94, left hemisphere 30.6
1846 Male, age 80, right hemisphere 29.7
2856 Male, age 75, right hemisphere 25.3
Orbitofrontal gyrus, anterior
nTPM: 19.8
2864 Female, age 67, left hemisphere 27.8
2862 Female, age 85, left hemisphere 21.2
2863 Female, age 85, right hemisphere 10.4
Paracentral lobule, anterior
nTPM: 27.0
1926 Male, age 61, left hemisphere 35.0
2340 Female, age 67, right hemisphere 29.0
1754 Male, age 75, left hemisphere 27.2
2638 Female, age 94, right hemisphere 25.8
2474 Male, age 74, left hemisphere 25.4
1776 Female, age 85, right hemisphere 19.7
Paracentral lobule, posterior
nTPM: 28.6
2551 Female, age 94, right hemisphere 38.5
2446 Male, age 75, left hemisphere 31.0
1775 Female, age 85, right hemisphere 25.9
1764 Male, age 74, right hemisphere 25.0
2345 Male, age 61, left hemisphere 22.8
Parietal operculum
nTPM: 22.4
2552 Female, age 94, right hemisphere 28.8
1763 Male, age 74, left hemisphere 22.6
2356 Female, age 67, right hemisphere 19.9
2719 Male, age 75, left hemisphere 18.2
Parieto-insular cortex
nTPM: 27.6
1976 Female, age 91, right hemisphere 39.3
2508 Female, age 94, right hemisphere 30.8
2232 Male, age 61, right hemisphere 26.5
2671 Male, age 75, left hemisphere 23.8
2831 Male, age 76, right hemisphere 17.8
Parieto-occipital transitional area
nTPM: 29.3
1784 Male, age 76, right hemisphere 38.5
2468 Male, age 75, left hemisphere 30.0
2683 Female, age 67, left hemisphere 27.5
2674 Female, age 94, right hemisphere 26.7
2270 Male, age 61, right hemisphere 23.9
Piriform cortex
nTPM: 40.9
2347 Male, age 75, right hemisphere 43.6
2153 Female, age 85, left hemisphere 38.2
Postcentral gyrus
nTPM: 23.8
2533 Male, age 75, right hemisphere 23.8
Postcentral gyrus, dorsal
nTPM: 30.5
2339 Female, age 67, right hemisphere 34.9
1836 Female, age 85, right hemisphere 32.2
2477 Female, age 94, right hemisphere 31.0
2151 Male, age 61, left hemisphere 30.6
2350 Male, age 75, left hemisphere 29.1
2544 Male, age 74, left hemisphere 25.5
Postcentral gyrus, middle
nTPM: 27.1
2248 Male, age 61, left hemisphere 34.4
1897 Female, age 85, right hemisphere 31.4
2146 Female, age 67, right hemisphere 28.6
2444 Male, age 75, left hemisphere 25.2
2545 Male, age 74, left hemisphere 15.9
Postcentral gyrus, ventral
nTPM: 28.1
2024 Female, age 85, right hemisphere 33.4
2836 Female, age 94, right hemisphere 25.6
2445 Male, age 75, left hemisphere 25.4
Posterior cingulate cortex
nTPM: 34.8
2553 Female, age 94, right hemisphere 38.9
1759 Male, age 74, right hemisphere 37.5
2473 Male, age 75, left hemisphere 28.1
Posterior cingulate cortex, dorsal
nTPM: 32.7
2540 Male, age 75, right hemisphere 35.2
2343 Male, age 61, left hemisphere 35.1
2556 Female, age 67, right hemisphere 33.4
2641 Female, age 94, right hemisphere 33.3
2076 Female, age 85, right hemisphere 29.8
2634 Male, age 74, left hemisphere 29.3
Posterior cingulate cortex, ventral
nTPM: 29.0
2448 Female, age 67, right hemisphere 31.5
1994 Female, age 85, right hemisphere 31.3
1762 Female, age 94, right hemisphere 30.4
2635 Male, age 74, left hemisphere 29.1
2541 Male, age 75, right hemisphere 28.9
2346 Male, age 61, left hemisphere 22.9
Posterior insular cortex
nTPM: 25.9
1823 Male, age 76, right hemisphere 29.1
2511 Female, age 67, right hemisphere 28.4
2603 Female, age 94, left hemisphere 26.0
2231 Male, age 61, left hemisphere 25.3
2597 Male, age 75, left hemisphere 24.2
2832 Female, age 91, right hemisphere 22.2
Precentral gyrus
nTPM: 29.7
2557 Male, age 75, right hemisphere 29.7
Precentral gyrus, dorsal
nTPM: 28.8
2476 Female, age 94, right hemisphere 36.4
2442 Male, age 75, left hemisphere 30.8
1756 Male, age 74, left hemisphere 26.1
2354 Female, age 67, right hemisphere 21.9
Precentral gyrus, middle
nTPM: 32.7
1969 Female, age 67, right hemisphere 38.3
1909 Male, age 61, left hemisphere 33.8
2475 Male, age 74, right hemisphere 33.6
2443 Male, age 75, left hemisphere 32.3
2549 Female, age 94, right hemisphere 25.7
Precentral gyrus, ventral
nTPM: 26.5
2662 Female, age 67, right hemisphere 34.2
2550 Female, age 94, right hemisphere 24.5
2678 Male, age 74, left hemisphere 23.8
2630 Male, age 75, left hemisphere 23.2
Precuneus
nTPM: 30.0
1782 Male, age 76, right hemisphere 38.6
2467 Male, age 75, right hemisphere 36.4
2510 Female, age 67, right hemisphere 32.9
2673 Female, age 94, right hemisphere 30.9
1780 Female, age 91, right hemisphere 21.9
2594 Male, age 61, left hemisphere 19.2
Premotor cortex, dorsal
nTPM: 29.9
2554 Female, age 67, right hemisphere 34.4
1878 Female, age 85, right hemisphere 31.3
2027 Male, age 61, left hemisphere 30.7
2631 Male, age 74, left hemisphere 27.0
2536 Male, age 75, left hemisphere 26.1
Premotor cortex, ventral
nTPM: 23.5
2349 Male, age 75, left hemisphere 27.8
1881 Female, age 85, right hemisphere 26.2
2637 Female, age 94, right hemisphere 25.1
1777 Female, age 67, left hemisphere 22.8
1779 Male, age 61, left hemisphere 19.6
1757 Male, age 74, left hemisphere 19.2
Retrosplenial cortex
nTPM: 35.5
1914 Male, age 76, right hemisphere 37.9
2675 Female, age 94, left hemisphere 35.1
1951 Male, age 61, right hemisphere 33.4
Subcentral gyrus, S2
nTPM: 29.0
2072 Male, age 61, left hemisphere 34.8
1964 Female, age 85, right hemisphere 33.9
2762 Male, age 74, left hemisphere 29.7
2555 Female, age 67, right hemisphere 28.2
2351 Male, age 75, left hemisphere 27.9
2839 Female, age 94, right hemisphere 19.5
Superior parietal lobule
nTPM: 34.6
1800 Male, age 76, right hemisphere 42.9
1992 Female, age 91, right hemisphere 35.1
2605 Female, age 67, right hemisphere 34.8
2672 Female, age 94, right hemisphere 30.6
2229 Male, age 61, right hemisphere 29.6
Superior temporal gyrus
nTPM: 29.5
1844 Female, age 91, left hemisphere 37.3
2025 Male, age 80, right hemisphere 33.8
1843 Male, age 76, left hemisphere 27.2
2615 Female, age 94, left hemisphere 25.7
2687 Male, age 75, right hemisphere 23.5
Supplementary motor cortex
nTPM: 28.3
2548 Female, age 94, right hemisphere 32.7
1993 Male, age 61, left hemisphere 30.4
2632 Male, age 74, left hemisphere 25.9
2537 Male, age 75, left hemisphere 24.1
Supramarginal gyrus
nTPM: 29.7
1991 Female, age 91, right hemisphere 34.5
1798 Male, age 76, right hemisphere 34.1
2601 Female, age 94, left hemisphere 28.7
2415 Male, age 61, left hemisphere 27.7
2513 Female, age 72, left hemisphere 23.3
Temporal pole
nTPM: 31.8
2518 Male, age 75, right hemisphere 38.7
1853 Female, age 85, right hemisphere 34.8
2612 Female, age 94, left hemisphere 31.1
1826 Male, age 76, right hemisphere 27.4
1832 Female, age 91, left hemisphere 27.2
Temporo-insular cortex, parainsular gyrus
nTPM: 29.7
2512 Female, age 67, right hemisphere 37.4
1802 Male, age 76, left hemisphere 34.0
2264 Female, age 91, right hemisphere 29.3
2416 Male, age 61, right hemisphere 29.3
2676 Female, age 94, right hemisphere 25.1
2598 Male, age 75, left hemisphere 23.3
Temporo-occipital transitional zone
nTPM: 32.0
1793 Male, age 80, right hemisphere 33.9
1900 Male, age 76, left hemisphere 32.9
2251 Female, age 85, right hemisphere 29.2
Transversal temporal gyrus, anterior
nTPM: 29.3
1910 Male, age 80, right hemisphere 34.7
1888 Female, age 91, left hemisphere 32.1
1809 Male, age 76, right hemisphere 31.4
2610 Male, age 75, right hemisphere 24.2
2522 Female, age 94, left hemisphere 23.9
Transversal temporal gyrus, posterior
nTPM: 27.7
1967 Female, age 91, right hemisphere 35.1
2520 Male, age 75, right hemisphere 31.4
1922 Male, age 76, left hemisphere 27.6
2614 Female, age 94, left hemisphere 25.8
2833 Male, age 80, right hemisphere 18.4

CEREBRAL CORTEX - HPA PFC Brain RNA-seq
Max nTPM 47.7
Sample id Sample description nTPM
Anterior cingulate gyrus, pregenual-dorsal
nTPM: 39.6
1516 Female, age 85, left hemisphere 59.4
1512 Male, age 75, left hemisphere 47.5
1517 Female, age 67, left hemisphere 46.6
1510 Male, age 61, left hemisphere 44.8
1513 Male, age 74, left hemisphere 42.5
1518 Female, age 67, right hemisphere 40.7
1511 Male, age 61, right hemisphere 37.3
1514 Male, age 74, right hemisphere 24.2
1515 Female, age 94, right hemisphere 13.8
Anterior cingulate gyrus, pregenual-ventral
nTPM: 32.6
1519 Male, age 61, left hemisphere 49.6
1520 Male, age 75, right hemisphere 44.4
1521 Male, age 74, left hemisphere 34.5
1523 Female, age 67, left hemisphere 23.5
1522 Male, age 74, right hemisphere 10.8
Anterior cingulate gyrus, subgenual
nTPM: 47.7
1525 Male, age 75, left hemisphere 72.6
1527 Male, age 74, left hemisphere 63.6
1526 Male, age 75, right hemisphere 58.3
1524 Male, age 61, left hemisphere 49.2
1528 Male, age 74, right hemisphere 39.9
1529 Female, age 85, left hemisphere 29.6
1530 Female, age 67, right hemisphere 20.5
Dorsolateral prefrontal cortex
nTPM: 4.5
1449 Female, age 85, right hemisphere 12.5
1450 Female, age 67, right hemisphere 7.1
1444 Male, age 75, left hemisphere 5.4
1445 Male, age 75, right hemisphere 2.2
1448 Female, age 94, right hemisphere 1.7
1447 Female, age 94, left hemisphere 1.4
1446 Male, age 74, right hemisphere 1.2
Dorsomedial prefrontal cortex
nTPM: 5.0
1439 Male, age 61, left hemisphere 12.4
1442 Male, age 75, right hemisphere 6.4
1440 Male, age 61, right hemisphere 4.0
1441 Male, age 75, left hemisphere 1.4
1443 Female, age 67, right hemisphere 0.8
Frontal cortex
nTPM: 4.5
1575 Male, age 75, right hemisphere 10.3
1581 Female, age 85, right hemisphere 8.2
1574 Male, age 75, left hemisphere 7.7
1580 Female, age 85, left hemisphere 5.4
1573 Male, age 61, right hemisphere 4.1
1583 Female, age 67, right hemisphere 4.1
1579 Female, age 94, right hemisphere 3.8
1582 Female, age 67, left hemisphere 3.3
1578 Female, age 94, left hemisphere 2.7
1572 Male, age 61, left hemisphere 1.7
1576 Male, age 74, left hemisphere 1.6
1577 Male, age 74, right hemisphere 0.9
Frontomarginal cortex
nTPM: 6.2
1471 Female, age 85, left hemisphere 14.8
1472 Female, age 67, left hemisphere 8.8
1469 Female, age 94, left hemisphere 6.7
1470 Female, age 94, right hemisphere 5.7
1473 Female, age 67, right hemisphere 5.6
1468 Male, age 74, left hemisphere 5.4
1466 Male, age 61, right hemisphere 3.0
1467 Male, age 75, right hemisphere 3.0
1465 Male, age 61, left hemisphere 2.9
Frontopolar cortex
nTPM: 6.7
1464 Female, age 67, right hemisphere 11.5
1462 Female, age 94, left hemisphere 10.8
1463 Female, age 67, left hemisphere 10.8
1458 Male, age 61, left hemisphere 4.6
1459 Male, age 61, right hemisphere 4.3
1461 Male, age 75, right hemisphere 3.6
1460 Male, age 75, left hemisphere 1.3
Gyrus rectus
nTPM: 3.2
1478 Female, age 94, left hemisphere 5.4
1477 Male, age 75, right hemisphere 4.7
1476 Male, age 75, left hemisphere 4.0
1479 Female, age 94, right hemisphere 3.7
1480 Female, age 85, left hemisphere 3.5
1481 Female, age 67, left hemisphere 2.8
1475 Male, age 61, right hemisphere 1.1
1474 Male, age 61, left hemisphere 0.6
Inferior frontal gyrus, orbital
nTPM: 35.6
1503 Male, age 75, right hemisphere 61.0
1502 Male, age 75, left hemisphere 60.2
1501 Male, age 61, right hemisphere 47.6
1509 Female, age 67, right hemisphere 39.0
1500 Male, age 61, left hemisphere 36.5
1505 Male, age 74, right hemisphere 32.9
1508 Female, age 85, right hemisphere 32.3
1504 Male, age 74, left hemisphere 27.1
1506 Female, age 94, left hemisphere 13.9
1507 Female, age 85, left hemisphere 5.5
Inferior frontal gyrus, triangular
nTPM: 30.5
1544 Male, age 75, right hemisphere 49.5
1547 Female, age 85, left hemisphere 33.3
1543 Male, age 61, right hemisphere 32.4
1545 Male, age 74, right hemisphere 31.3
1549 Female, age 67, left hemisphere 28.7
1542 Male, age 61, left hemisphere 26.7
1546 Female, age 94, right hemisphere 21.2
1548 Female, age 85, right hemisphere 20.8
Orbitofrontal gyrus, lateral
nTPM: 29.2
1494 Male, age 75, left hemisphere 56.4
1495 Female, age 94, left hemisphere 35.8
1493 Male, age 61, right hemisphere 29.7
1497 Female, age 85, left hemisphere 26.9
1499 Female, age 67, right hemisphere 26.0
1496 Female, age 94, right hemisphere 21.0
1498 Female, age 85, right hemisphere 8.7
Orbitofrontal gyrus, medial
nTPM: 2.6
1491 Female, age 67, left hemisphere 5.1
1490 Female, age 85, right hemisphere 5.0
1489 Female, age 85, left hemisphere 4.7
1483 Male, age 75, left hemisphere 4.3
1482 Male, age 61, left hemisphere 3.4
1484 Male, age 75, right hemisphere 1.8
1492 Female, age 67, right hemisphere 1.7
1487 Female, age 94, left hemisphere 1.4
1488 Female, age 94, right hemisphere 0.9
1486 Male, age 74, right hemisphere 0.4
1485 Male, age 74, left hemisphere 0.0
Orbitofrontal gyrus, posterior
nTPM: 36.4
1535 Male, age 74, left hemisphere 55.6
1533 Male, age 75, left hemisphere 42.2
1534 Male, age 75, right hemisphere 41.5
1536 Female, age 94, left hemisphere 37.6
1539 Female, age 85, right hemisphere 37.6
1541 Female, age 67, right hemisphere 37.3
1540 Female, age 67, left hemisphere 32.4
1538 Female, age 85, left hemisphere 30.1
1532 Male, age 61, right hemisphere 30.0
1537 Female, age 94, right hemisphere 28.5
1531 Male, age 61, left hemisphere 27.0
Subcallosal gyrus
nTPM: 4.2
1556 Female, age 94, left hemisphere 11.9
1551 Male, age 61, right hemisphere 6.2
1560 Female, age 67, left hemisphere 5.5
1558 Female, age 85, left hemisphere 4.9
1554 Male, age 74, left hemisphere 4.1
1555 Male, age 74, right hemisphere 3.6
1557 Female, age 94, right hemisphere 3.4
1559 Female, age 85, right hemisphere 3.4
1552 Male, age 75, left hemisphere 2.8
1553 Male, age 75, right hemisphere 2.0
1561 Female, age 67, right hemisphere 1.3
1550 Male, age 61, left hemisphere 1.0
Superior frontal gyrus
nTPM: 5.8
1564 Male, age 75, left hemisphere 15.4
1562 Male, age 61, left hemisphere 9.0
1566 Male, age 74, right hemisphere 8.2
1565 Male, age 75, right hemisphere 7.5
1563 Male, age 61, right hemisphere 6.8
1570 Female, age 85, right hemisphere 5.7
1569 Female, age 85, left hemisphere 2.5
1568 Female, age 94, right hemisphere 1.8
1567 Female, age 94, left hemisphere 1.1
1571 Female, age 67, right hemisphere 0.0
Temporal cortex
nTPM: 3.9
1595 Female, age 94, right hemisphere 6.6
1592 Male, age 74, left hemisphere 5.4
1593 Male, age 74, right hemisphere 5.1
1594 Female, age 94, left hemisphere 3.9
1596 Female, age 85, right hemisphere 3.6
1590 Male, age 61, right hemisphere 1.6
1591 Male, age 75, right hemisphere 0.8
Ventrolateral prefrontal cortex
nTPM: 9.0
1456 Female, age 67, left hemisphere 21.1
1451 Male, age 75, right hemisphere 10.5
1457 Female, age 67, right hemisphere 10.5
1455 Female, age 85, right hemisphere 9.4
1452 Male, age 74, left hemisphere 6.1
1454 Female, age 94, left hemisphere 2.8
1453 Male, age 74, right hemisphere 2.4
Ventromedial prefrontal cortex
nTPM: 6.8
1433 Male, age 61, right hemisphere 10.6
1432 Male, age 61, left hemisphere 9.7
1435 Female, age 94, right hemisphere 9.2
1438 Female, age 67, left hemisphere 7.0
1434 Male, age 75, right hemisphere 5.5
1436 Female, age 85, left hemisphere 3.6
1437 Female, age 85, right hemisphere 1.9

CEREBRAL CORTEX - GTEx RNA-seqi
Average nTPM 54.0
GTEx sample id Sample description nTPM
Brain - Anterior cingulate cortex (BA24)
Average nTPM: 54.0
Samples: 176

Max nTPM: 183.9
Min nTPM: 13.5
Std nTPM: 18.7
Median nTPM: 53.4
GTEX-1H3VE-0011-R3a-SM-CE6SK 40-49 years, male 183.9
GTEX-12ZZW-0011-R3a-SM-5DUWW 50-59 years, male 99.7
GTEX-1IKK5-0011-R3b-SM-C1YRY 60-69 years, male 95.8
GTEX-13PLJ-0011-R3a-SM-5O9DT 60-69 years, female 94.8
GTEX-1H2FU-0011-R3b-SM-CKZP4 60-69 years, female 92.1
GTEX-14JG1-0011-R3a-SM-62LEC 40-49 years, male 88.3
GTEX-ZE9C-0011-R3a-SM-4WKGT 60-69 years, male 87.6
GTEX-16XZZ-0011-R3a-SM-7IGLH 60-69 years, male 85.4
GTEX-139TT-0011-R3b-SM-5K7VL 60-69 years, male 83.5
GTEX-139T8-0011-R3b-SM-5HL4R 60-69 years, male 82.7
GTEX-1MCQQ-0011-R3a-SM-EXURW 60-69 years, male 82.1
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Brain - Cortex
Average nTPM: 43.6
Samples: 255

Max nTPM: 83.0
Min nTPM: 16.1
Std nTPM: 10.9
Median nTPM: 42.0
GTEX-15UF6-3026-SM-7KUKL 70-79 years, female 83.0
GTEX-1C6VQ-3026-SM-7IGPU 50-59 years, male 78.3
GTEX-1NV5F-3226-SM-EXUSL 60-69 years, female 77.1
GTEX-1HBPM-2926-SM-CL54E 60-69 years, female 76.5
GTEX-1JJE9-2926-SM-CY8HV 70-79 years, male 75.6
GTEX-1445S-3026-SM-5O9BR 60-69 years, male 74.2
GTEX-1H3VE-2726-SM-9WPP3 40-49 years, male 72.5
GTEX-1M4P7-2726-SM-E9TJQ 60-69 years, male 69.4
GTEX-1N2DW-2826-SM-E9TK5 50-59 years, male 66.9
GTEX-1A8G7-3126-SM-7IGP7 60-69 years, male 64.1
GTEX-1117F-3226-SM-5N9CT 60-69 years, female 64.0
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Brain - Frontal Cortex (BA9)
Average nTPM: 46.3
Samples: 209

Max nTPM: 100.2
Min nTPM: 16.3
Std nTPM: 14.7
Median nTPM: 44.5
GTEX-1IL2V-0011-R10a-SM-CL55A 70-79 years, male 100.2
GTEX-1C6VQ-0011-R10b-SM-7P8Q1 50-59 years, male 98.6
GTEX-13O3O-0011-R10a-SM-5LUA9 60-69 years, female 94.0
GTEX-15UF6-0011-R10b-SM-9OSVF 70-79 years, female 88.9
GTEX-131XW-0011-R10a-SM-5DUVA 50-59 years, female 87.0
GTEX-13IVO-0011-R10a-SM-5LZY3 70-79 years, male 86.8
GTEX-1477Z-0011-R10b-SM-5S2RF 60-69 years, male 80.0
GTEX-1HBPM-0011-R10a-SM-CJI3Q 60-69 years, female 79.9
GTEX-1GF9V-0011-R10b-SM-CKZNP 60-69 years, male 78.7
GTEX-1H3VE-0011-R10b-SM-A9SKC 40-49 years, male 78.4
GTEX-1I1CD-0011-R10b-SM-CJI3W 60-69 years, female 77.6
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CEREBRAL CORTEX - FANTOM5 CAGEi
Max Scaled Tags Per Million 43.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Occipital cortex
Scaled Tags Per Million: 29.0
FF:10163-103B1 76 years, female 29.0
Postcentral gyrus
Scaled Tags Per Million: 29.5
FF:10032-101E5 44-52 years, mixed 29.5
Frontal lobe
Scaled Tags Per Million: 20.2
FF:10040-101F4 32-61 years, mixed 20.2
Insula
Scaled Tags Per Million: 24.3
FF:10039-101F3 20-68 years, mixed 24.3
Medial frontal gyrus
Scaled Tags Per Million: 24.0
FF:10150-102I6 76 years, female 24.0
Medial temporal gyrus
Scaled Tags Per Million: 30.5
FF:10183-103D3 60 years, female 35.3
FF:10156-103A3 76 years, female 25.7
Occipital lobe
Scaled Tags Per Million: 43.7
FF:10076-102A4 27 years, male 43.7
Occipital pole
Scaled Tags Per Million: 28.7
FF:10036-101E9 22-68 years, mixed 28.7
Paracentral gyrus
Scaled Tags Per Million: 22.4
FF:10035-101E8 22-69 years, mixed 22.4
Parietal lobe
Scaled Tags Per Million: 27.0
FF:10171-103B9 60 years, female 31.9
FF:10034-101E7 35-89 years, mixed 24.5
FF:10157-103A4 76 years, female 24.4
Temporal lobe
Scaled Tags Per Million: 34.6
FF:10031-101E4 32-61 years, mixed 34.6

CEREBRAL CORTEX - Pig RNA-seqi
Average nTPM 15.0
Pig sample Sample description nTPM
Occipital cortex
nTPM: 13.4
Samples: 4

Max nTPM: 16.1
Min nTPM: 8.7
Sample A Female 16.1
Sample B Female 8.7
Sample C Male 16.1
Sample D Male 12.8
Retrosplenial cortex
nTPM: 13.2
Samples: 4

Max nTPM: 15.8
Min nTPM: 10.5
Sample A Female 15.8
Sample B Female 13.1
Sample C Male 13.5
Sample D Male 10.5
Cingulate cortex
nTPM: 13.1
Samples: 4

Max nTPM: 14.2
Min nTPM: 11.3
Sample A Female 13.7
Sample B Female 13.3
Sample C Male 14.2
Sample D Male 11.3
Insular cortex
nTPM: 13.3
Samples: 4

Max nTPM: 14.6
Min nTPM: 12.1
Sample A Female 14.6
Sample B Female 12.8
Sample C Male 13.6
Sample D Male 12.1
Motor cortex
nTPM: 15.0
Samples: 4

Max nTPM: 16.9
Min nTPM: 12.9
Sample A Female 16.0
Sample B Female 14.1
Sample C Male 16.9
Sample D Male 12.9
Prefrontal cortex
nTPM: 13.1
Samples: 4

Max nTPM: 14.5
Min nTPM: 11.9
Sample A Female 11.9
Sample B Female 13.5
Sample C Male 14.5
Sample D Male 12.5
Somatosensory cortex
nTPM: 15.0
Samples: 3

Max nTPM: 15.9
Min nTPM: 13.8
Sample B Female 13.8
Sample C Male 15.4
Sample D Male 15.9
Temporal cortex
nTPM: 14.1
Samples: 4

Max nTPM: 15.6
Min nTPM: 12.6
Sample A Female 14.3
Sample B Female 12.6
Sample C Male 15.6
Sample D Male 13.7

CEREBRAL CORTEX - Mouse RNA-seqi
Average nTPM 42.1
Mouse sample Sample description nTPM
Occipital cortex
nTPM: 38.1
Samples: 4

Max nTPM: 51.3
Min nTPM: 25.4
Sample A Male 41.7
Sample B Male 25.4
Sample C Female 34.0
Sample D Female 51.3
Frontal cortex
nTPM: 35.8
Samples: 4

Max nTPM: 41.8
Min nTPM: 28.9
Sample A Male 28.9
Sample B Male 41.8
Sample C Female 38.6
Sample D Female 33.8
Retrosplenial and cingulate cortex
nTPM: 37.3
Samples: 4

Max nTPM: 41.9
Min nTPM: 33.3
Sample A Male 38.4
Sample B Male 41.9
Sample C Female 35.6
Sample D Female 33.3
Somatosensory cortex
nTPM: 42.1
Samples: 4

Max nTPM: 51.0
Min nTPM: 27.9
Sample A Male 27.9
Sample B Male 51.0
Sample C Female 38.9
Sample D Female 50.5

CEREBRAL CORTEX - Allen Mouse ISHi
Max Expression energy 2.4
Allen experiment id Experiment description Expression energy
Cerebral cortex
Expression energy: 2.4
68744839 Antisense, RP_050208_01_G05, Mouse strain C57BL/6J (56 days, male) 2.4

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