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CMC2
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  • CMC2
PROTEIN SUMMARY SECTION OVERVIEW GENE INFORMATION RNA DATA ANTIBODY DATA
GENERAL INFORMATIONi

General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.

Gene namei

Official gene symbol, which is typically a short form of the gene name, according to HGNC.

CMC2
Synonyms C16orf61, DC13, MGC45036
Gene descriptioni

Full gene name according to HGNC.

C-X9-C motif containing 2
Predicted locationi

All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions.

  • Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached.

  • Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s).

The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location.

Intracellular
Protein evidence Evidence at protein level (all genes)
GENE INFORMATIONi

Gene information from Ensembl and Entrez, as well as links to available gene identifiers are displayed here. Information was retrieved from Ensembl if not indicated otherwise.

Chromosome 16
Cytoband q23.2
Chromosome location (bp) 80966448 - 81020270
Number of transcriptsi

Number of protein-coding transcripts from the gene as defined by Ensembl.

11
Ensembl ENSG00000103121 (version 109)
Entrez gene 56942
HGNC HGNC:24447
UniProt Q9NRP2 (UniProt - Evidence at protein level)
neXtProt NX_Q9NRP2
GeneCards CMC2
Antibodypedia CMC2 antibodies


PROTEIN FUNCTION
Protein function (UniProt)i

Useful information about the protein provided by UniProt.

May be involved in cytochrome c oxidase biogenesis.... show less
Gene summary (Entrez)i

Useful information about the gene from Entrez

Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]... show less
PROTEIN INFORMATIONi

The protein information section displays alternative protein-coding transcripts (splice variants) encoded by this gene according to the Ensembl database.

The ENSP identifier links to the Ensembl website protein summary, while the ENST identifier links to the Ensembl website transcript summary for the selected splice variant. The data in the UniProt column can be expanded to show links to all matching UniProt identifiers for this protein.

The protein classes assigned to this protein are shown if expanding the data in the protein class column. Parent protein classes are in bold font and subclasses are listed under the parent class.

The Gene Ontology terms assigned to this protein are listed if expanding the Gene ontology column. The length of the protein (amino acid residues according to Ensembl), molecular mass (kDalton), predicted signal peptide (according to a majority of the signal peptide predictors SPOCTOPUS, SignalP 4.0, and Phobius) and the number of predicted transmembrane region(s) (according to MDM) are also reported.
Splice variant SwissProt TrEMBL Protein class Gene ontology Length & mass Signal peptide
(predicted)
Transmembrane regions
(predicted)
CMC2-201
ENSP00000219400
ENST00000219400
Q9NRP2
[Direct mapping] COX assembly mitochondrial protein 2 homolog
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005739 [mitochondrion]
Show all
79 aa
9.5 kDa
No 0
CMC2-202
ENSP00000456177
ENST00000486645
H3BRC3
[Direct mapping] COX assembly mitochondrial protein
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005739 [mitochondrion]
Show all
50 aa
5.6 kDa
No 0
CMC2-204
ENSP00000457938
ENST00000562713
H3BNN8
[Direct mapping] COX assembly mitochondrial protein
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005739 [mitochondrion]
Show all
74 aa
8.6 kDa
No 0
CMC2-207
ENSP00000455404
ENST00000564174
H3BPP2
[Direct mapping] COX assembly mitochondrial protein
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005739 [mitochondrion]
Show all
55 aa
6.5 kDa
No 0
CMC2-208
ENSP00000456841
ENST00000564249
Q9NRP2
[Direct mapping] COX assembly mitochondrial protein 2 homolog
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005739 [mitochondrion]
Show all
79 aa
9.5 kDa
No 0
CMC2-209
ENSP00000454240
ENST00000565108
H3BPP2
[Direct mapping] COX assembly mitochondrial protein
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005739 [mitochondrion]
Show all
55 aa
6.5 kDa
No 0
CMC2-212
ENSP00000455457
ENST00000565650
Q9NRP2
[Direct mapping] COX assembly mitochondrial protein 2 homolog
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005739 [mitochondrion]
Show all
79 aa
9.5 kDa
No 0
CMC2-213
ENSP00000455723
ENST00000565914
Q9NRP2
[Direct mapping] COX assembly mitochondrial protein 2 homolog
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005739 [mitochondrion]
Show all
79 aa
9.5 kDa
No 0
CMC2-214
ENSP00000454396
ENST00000565925
H3BNN8
[Direct mapping] COX assembly mitochondrial protein
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005739 [mitochondrion]
Show all
74 aa
8.6 kDa
No 0
CMC2-223
ENSP00000457106
ENST00000570195
H3BTB6
[Direct mapping] COX assembly mitochondrial protein
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005739 [mitochondrion]
Show all
93 aa
10.6 kDa
No 0
CMC2-224
ENSP00000487053
ENST00000630396
H3BTB6
[Direct mapping] COX assembly mitochondrial protein
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005739 [mitochondrion]
Show all
93 aa
10.6 kDa
No 0

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