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RASL12
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  • RASL12
PROTEIN SUMMARY SECTION OVERVIEW GENE INFORMATION RNA DATA
GENERAL INFORMATIONi

General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.

Gene namei

Official gene symbol, which is typically a short form of the gene name, according to HGNC.

RASL12
Synonyms RIS
Gene descriptioni

Full gene name according to HGNC.

RAS like family 12
Protein classi

Assigned HPA protein class(es) for the encoded protein(s).

Enzymes
Predicted locationi

All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions.

  • Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached.

  • Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s).

The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location.

Intracellular
Protein evidence Evidence at protein level (all genes)
GENE INFORMATIONi

Gene information from Ensembl and Entrez, as well as links to available gene identifiers are displayed here. Information was retrieved from Ensembl if not indicated otherwise.

Chromosome 15
Cytoband q22.31
Chromosome location (bp) 65053337 - 65076690
Number of transcriptsi

Number of protein-coding transcripts from the gene as defined by Ensembl.

3
Ensembl ENSG00000103710 (version 109)
Entrez gene 51285
HGNC HGNC:30289
UniProt Q9NYN1 (UniProt - Evidence at protein level)
neXtProt NX_Q9NYN1
GeneCards RASL12
Antibodypedia RASL12 antibodies


PROTEIN FUNCTION
Molecular function (UniProt)i

Keywords assigned by UniProt to proteins due to their particular molecular function.

Hydrolase
Ligand (UniProt)i

Keywords assigned by UniProt to proteins because they bind, are associated with, or whose activity is dependent of some molecule.

GTP-binding, Nucleotide-binding
Gene summary (Entrez)i

Useful information about the gene from Entrez

Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Predicted to be involved in signal transduction. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]... show less
PROTEIN INFORMATIONi

The protein information section displays alternative protein-coding transcripts (splice variants) encoded by this gene according to the Ensembl database.

The ENSP identifier links to the Ensembl website protein summary, while the ENST identifier links to the Ensembl website transcript summary for the selected splice variant. The data in the UniProt column can be expanded to show links to all matching UniProt identifiers for this protein.

The protein classes assigned to this protein are shown if expanding the data in the protein class column. Parent protein classes are in bold font and subclasses are listed under the parent class.

The Gene Ontology terms assigned to this protein are listed if expanding the Gene ontology column. The length of the protein (amino acid residues according to Ensembl), molecular mass (kDalton), predicted signal peptide (according to a majority of the signal peptide predictors SPOCTOPUS, SignalP 4.0, and Phobius) and the number of predicted transmembrane region(s) (according to MDM) are also reported.
Splice variant SwissProt TrEMBL Protein class Gene ontology Length & mass Signal peptide
(predicted)
Transmembrane regions
(predicted)
RASL12-201
ENSP00000220062
ENST00000220062
Q9NYN1
[Direct mapping] Ras-like protein family member 12
Show all
A0A024R5Y3
[Target identity:100%; Query identity:100%] RAS-like, family 12, isoform CRA_a
Show all
Enzymes
   ENZYME proteins
   Hydrolases
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Kim et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0003924 [GTPase activity]
GO:0003925 [G protein activity]
GO:0005515 [protein binding]
GO:0005525 [GTP binding]
GO:0005886 [plasma membrane]
GO:0007165 [signal transduction]
GO:0016020 [membrane]
GO:0016787 [hydrolase activity]
GO:0019003 [GDP binding]
Show all
266 aa
29.7 kDa
No 0
RASL12-202
ENSP00000390028
ENST00000421977
Q9NYN1
[Direct mapping] Ras-like protein family member 12
Show all
Enzymes
   ENZYME proteins
   Hydrolases
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Show all
GO:0000166 [nucleotide binding]
GO:0003924 [GTPase activity]
GO:0003925 [G protein activity]
GO:0005515 [protein binding]
GO:0005525 [GTP binding]
GO:0005886 [plasma membrane]
GO:0007165 [signal transduction]
GO:0016020 [membrane]
GO:0016787 [hydrolase activity]
GO:0019003 [GDP binding]
Show all
247 aa
27.4 kDa
No 0
RASL12-203
ENSP00000412787
ENST00000434605
Q9NYN1
[Direct mapping] Ras-like protein family member 12
Show all
Enzymes
   ENZYME proteins
   Hydrolases
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Show all
GO:0000166 [nucleotide binding]
GO:0003924 [GTPase activity]
GO:0003925 [G protein activity]
GO:0005515 [protein binding]
GO:0005525 [GTP binding]
GO:0005886 [plasma membrane]
GO:0007165 [signal transduction]
GO:0016020 [membrane]
GO:0016787 [hydrolase activity]
GO:0019003 [GDP binding]
Show all
255 aa
28.8 kDa
No 0

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