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General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Gene namei
Official gene symbol, which is typically a short form of the gene name, according to HGNC.
Assigned HPA protein class(es) for the encoded protein(s).
Disease related genes Human disease related genes
Predicted locationi
All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions.
Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached.
Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s).
The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location.
Gene information from Ensembl and Entrez, as well as links to available gene identifiers are displayed here. Information was retrieved from Ensembl if not indicated otherwise.
Chromosome
7
Cytoband
q22.1
Chromosome location (bp)
100106876 - 100119841
Number of transcriptsi
Number of protein-coding transcripts from the gene as defined by Ensembl.
Useful information about the protein provided by UniProt.
The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription 1. TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC) 2. The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13 3. The TFIID complex structure can be divided into 3 modules TFIID-A, TFIID-B, and TFIID-C 4. TAF6 homodimer connects TFIID modules, forming a rigid core 5....show less
Biological process (UniProt)i
Keywords assigned by UniProt to proteins because they are involved in a particular biological process.
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the smaller subunits of TFIID that binds weakly to TBP but strongly to TAF1, the largest subunit of TFIID. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]...show less
PROTEIN INFORMATIONi
The protein information section displays alternative protein-coding transcripts (splice variants) encoded by this gene according to the Ensembl database.
The ENSP identifier links to the Ensembl website protein summary, while the ENST identifier links to the Ensembl website transcript summary for the selected splice variant. The data in the UniProt column can be expanded to show links to all matching UniProt identifiers for this protein.
The protein classes assigned to this protein are shown if expanding the data in the protein class column. Parent protein classes are in bold font and subclasses are listed under the parent class.
The Gene Ontology terms assigned to this protein are listed if expanding the Gene ontology column. The length of the protein (amino acid residues according to Ensembl), molecular mass (kDalton), predicted signal peptide (according to a majority of the signal peptide predictors SPOCTOPUS, SignalP 4.0, and Phobius) and the number of predicted transmembrane region(s) (according to MDM) are also reported.
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Disease related genes Human disease related genes Congenital malformations Other congenital malformations Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124[SAGA complex] GO:0003677[DNA binding] GO:0003713[transcription coactivator activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005669[transcription factor TFIID complex] GO:0005829[cytosol] GO:0006282[regulation of DNA repair] GO:0006352[DNA-templated transcription initiation] GO:0006357[regulation of transcription by RNA polymerase II] GO:0006366[transcription by RNA polymerase II] GO:0006367[transcription initiation at RNA polymerase II promoter] GO:0006468[protein phosphorylation] GO:0006915[apoptotic process] GO:0008285[negative regulation of cell population proliferation] GO:0016251[RNA polymerase II general transcription initiation factor activity] GO:0017162[aryl hydrocarbon receptor binding] GO:0032991[protein-containing complex] GO:0033276[transcription factor TFTC complex] GO:0035521[monoubiquitinated histone deubiquitination] GO:0035522[monoubiquitinated histone H2A deubiquitination] GO:0042789[mRNA transcription by RNA polymerase II] GO:0043966[histone H3 acetylation] GO:0045786[negative regulation of cell cycle] GO:0045893[positive regulation of DNA-templated transcription] GO:0046695[SLIK (SAGA-like) complex] GO:0046982[protein heterodimerization activity] GO:0051123[RNA polymerase II preinitiation complex assembly] GO:0060090[molecular adaptor activity] GO:0060261[positive regulation of transcription initiation by RNA polymerase II] GO:0071339[MLL1 complex]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Human disease related genes Congenital malformations Other congenital malformations Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124[SAGA complex] GO:0005669[transcription factor TFIID complex] GO:0006367[transcription initiation at RNA polymerase II promoter] GO:0016251[RNA polymerase II general transcription initiation factor activity] GO:0046695[SLIK (SAGA-like) complex] GO:0046982[protein heterodimerization activity]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Human disease related genes Congenital malformations Other congenital malformations Protein evidence (Ezkurdia et al 2014)
Phobius predicted secreted proteins Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Disease related genes Human disease related genes Congenital malformations Other congenital malformations Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124[SAGA complex] GO:0003677[DNA binding] GO:0003713[transcription coactivator activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005669[transcription factor TFIID complex] GO:0005829[cytosol] GO:0006282[regulation of DNA repair] GO:0006352[DNA-templated transcription initiation] GO:0006357[regulation of transcription by RNA polymerase II] GO:0006366[transcription by RNA polymerase II] GO:0006367[transcription initiation at RNA polymerase II promoter] GO:0006468[protein phosphorylation] GO:0006915[apoptotic process] GO:0016251[RNA polymerase II general transcription initiation factor activity] GO:0017162[aryl hydrocarbon receptor binding] GO:0032991[protein-containing complex] GO:0033276[transcription factor TFTC complex] GO:0035521[monoubiquitinated histone deubiquitination] GO:0035522[monoubiquitinated histone H2A deubiquitination] GO:0042789[mRNA transcription by RNA polymerase II] GO:0043966[histone H3 acetylation] GO:0045786[negative regulation of cell cycle] GO:0045893[positive regulation of DNA-templated transcription] GO:0046695[SLIK (SAGA-like) complex] GO:0046982[protein heterodimerization activity] GO:0051123[RNA polymerase II preinitiation complex assembly] GO:0060090[molecular adaptor activity] GO:0060261[positive regulation of transcription initiation by RNA polymerase II] GO:0071339[MLL1 complex] GO:2001244[positive regulation of intrinsic apoptotic signaling pathway]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Human disease related genes Congenital malformations Other congenital malformations Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124[SAGA complex] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005669[transcription factor TFIID complex] GO:0005829[cytosol] GO:0006367[transcription initiation at RNA polymerase II promoter] GO:0016251[RNA polymerase II general transcription initiation factor activity] GO:0046695[SLIK (SAGA-like) complex] GO:0046982[protein heterodimerization activity]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Human disease related genes Congenital malformations Other congenital malformations Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124[SAGA complex] GO:0005669[transcription factor TFIID complex] GO:0006367[transcription initiation at RNA polymerase II promoter] GO:0016251[RNA polymerase II general transcription initiation factor activity] GO:0046695[SLIK (SAGA-like) complex] GO:0046982[protein heterodimerization activity]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Human disease related genes Congenital malformations Other congenital malformations Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124[SAGA complex] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005669[transcription factor TFIID complex] GO:0005829[cytosol] GO:0006367[transcription initiation at RNA polymerase II promoter] GO:0016251[RNA polymerase II general transcription initiation factor activity] GO:0046695[SLIK (SAGA-like) complex] GO:0046982[protein heterodimerization activity]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Disease related genes Human disease related genes Congenital malformations Other congenital malformations Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124[SAGA complex] GO:0003677[DNA binding] GO:0003713[transcription coactivator activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005669[transcription factor TFIID complex] GO:0005829[cytosol] GO:0006282[regulation of DNA repair] GO:0006352[DNA-templated transcription initiation] GO:0006357[regulation of transcription by RNA polymerase II] GO:0006366[transcription by RNA polymerase II] GO:0006367[transcription initiation at RNA polymerase II promoter] GO:0006468[protein phosphorylation] GO:0006915[apoptotic process] GO:0008285[negative regulation of cell population proliferation] GO:0016251[RNA polymerase II general transcription initiation factor activity] GO:0017162[aryl hydrocarbon receptor binding] GO:0032991[protein-containing complex] GO:0033276[transcription factor TFTC complex] GO:0035521[monoubiquitinated histone deubiquitination] GO:0035522[monoubiquitinated histone H2A deubiquitination] GO:0042789[mRNA transcription by RNA polymerase II] GO:0043966[histone H3 acetylation] GO:0045786[negative regulation of cell cycle] GO:0045893[positive regulation of DNA-templated transcription] GO:0046695[SLIK (SAGA-like) complex] GO:0046982[protein heterodimerization activity] GO:0051123[RNA polymerase II preinitiation complex assembly] GO:0060090[molecular adaptor activity] GO:0060261[positive regulation of transcription initiation by RNA polymerase II] GO:0071339[MLL1 complex]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Human disease related genes Congenital malformations Other congenital malformations Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124[SAGA complex] GO:0005634[nucleus] GO:0005669[transcription factor TFIID complex] GO:0006367[transcription initiation at RNA polymerase II promoter] GO:0016251[RNA polymerase II general transcription initiation factor activity] GO:0046695[SLIK (SAGA-like) complex] GO:0046982[protein heterodimerization activity]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Disease related genes Human disease related genes Congenital malformations Other congenital malformations Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124[SAGA complex] GO:0003677[DNA binding] GO:0003713[transcription coactivator activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005669[transcription factor TFIID complex] GO:0005829[cytosol] GO:0006282[regulation of DNA repair] GO:0006352[DNA-templated transcription initiation] GO:0006357[regulation of transcription by RNA polymerase II] GO:0006366[transcription by RNA polymerase II] GO:0006367[transcription initiation at RNA polymerase II promoter] GO:0006468[protein phosphorylation] GO:0006915[apoptotic process] GO:0008285[negative regulation of cell population proliferation] GO:0016251[RNA polymerase II general transcription initiation factor activity] GO:0017162[aryl hydrocarbon receptor binding] GO:0032991[protein-containing complex] GO:0033276[transcription factor TFTC complex] GO:0035521[monoubiquitinated histone deubiquitination] GO:0035522[monoubiquitinated histone H2A deubiquitination] GO:0042789[mRNA transcription by RNA polymerase II] GO:0043966[histone H3 acetylation] GO:0045786[negative regulation of cell cycle] GO:0045893[positive regulation of DNA-templated transcription] GO:0046695[SLIK (SAGA-like) complex] GO:0046982[protein heterodimerization activity] GO:0051123[RNA polymerase II preinitiation complex assembly] GO:0060090[molecular adaptor activity] GO:0060261[positive regulation of transcription initiation by RNA polymerase II] GO:0071339[MLL1 complex]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Disease related genes Human disease related genes Congenital malformations Other congenital malformations Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124[SAGA complex] GO:0003677[DNA binding] GO:0003713[transcription coactivator activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005669[transcription factor TFIID complex] GO:0005829[cytosol] GO:0006282[regulation of DNA repair] GO:0006352[DNA-templated transcription initiation] GO:0006357[regulation of transcription by RNA polymerase II] GO:0006366[transcription by RNA polymerase II] GO:0006367[transcription initiation at RNA polymerase II promoter] GO:0006468[protein phosphorylation] GO:0006915[apoptotic process] GO:0008285[negative regulation of cell population proliferation] GO:0016251[RNA polymerase II general transcription initiation factor activity] GO:0017162[aryl hydrocarbon receptor binding] GO:0032991[protein-containing complex] GO:0033276[transcription factor TFTC complex] GO:0035521[monoubiquitinated histone deubiquitination] GO:0035522[monoubiquitinated histone H2A deubiquitination] GO:0042789[mRNA transcription by RNA polymerase II] GO:0043966[histone H3 acetylation] GO:0045786[negative regulation of cell cycle] GO:0045893[positive regulation of DNA-templated transcription] GO:0046695[SLIK (SAGA-like) complex] GO:0046982[protein heterodimerization activity] GO:0051123[RNA polymerase II preinitiation complex assembly] GO:0060090[molecular adaptor activity] GO:0060261[positive regulation of transcription initiation by RNA polymerase II] GO:0071339[MLL1 complex]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Disease related genes Human disease related genes Congenital malformations Other congenital malformations Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124[SAGA complex] GO:0003677[DNA binding] GO:0003713[transcription coactivator activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005669[transcription factor TFIID complex] GO:0005829[cytosol] GO:0006282[regulation of DNA repair] GO:0006352[DNA-templated transcription initiation] GO:0006357[regulation of transcription by RNA polymerase II] GO:0006366[transcription by RNA polymerase II] GO:0006367[transcription initiation at RNA polymerase II promoter] GO:0006468[protein phosphorylation] GO:0006915[apoptotic process] GO:0008285[negative regulation of cell population proliferation] GO:0016251[RNA polymerase II general transcription initiation factor activity] GO:0017162[aryl hydrocarbon receptor binding] GO:0032991[protein-containing complex] GO:0033276[transcription factor TFTC complex] GO:0035521[monoubiquitinated histone deubiquitination] GO:0035522[monoubiquitinated histone H2A deubiquitination] GO:0042789[mRNA transcription by RNA polymerase II] GO:0043966[histone H3 acetylation] GO:0045786[negative regulation of cell cycle] GO:0045893[positive regulation of DNA-templated transcription] GO:0046695[SLIK (SAGA-like) complex] GO:0046982[protein heterodimerization activity] GO:0051123[RNA polymerase II preinitiation complex assembly] GO:0060090[molecular adaptor activity] GO:0060261[positive regulation of transcription initiation by RNA polymerase II] GO:0071339[MLL1 complex]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Human disease related genes Congenital malformations Other congenital malformations Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124[SAGA complex] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005669[transcription factor TFIID complex] GO:0005829[cytosol] GO:0006367[transcription initiation at RNA polymerase II promoter] GO:0016251[RNA polymerase II general transcription initiation factor activity] GO:0046695[SLIK (SAGA-like) complex] GO:0046982[protein heterodimerization activity]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Human disease related genes Congenital malformations Other congenital malformations Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124[SAGA complex] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005669[transcription factor TFIID complex] GO:0005829[cytosol] GO:0006367[transcription initiation at RNA polymerase II promoter] GO:0016251[RNA polymerase II general transcription initiation factor activity] GO:0046695[SLIK (SAGA-like) complex] GO:0046982[protein heterodimerization activity]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Disease related genes Human disease related genes Congenital malformations Other congenital malformations Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124[SAGA complex] GO:0003677[DNA binding] GO:0003713[transcription coactivator activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005669[transcription factor TFIID complex] GO:0005829[cytosol] GO:0006282[regulation of DNA repair] GO:0006352[DNA-templated transcription initiation] GO:0006357[regulation of transcription by RNA polymerase II] GO:0006366[transcription by RNA polymerase II] GO:0006367[transcription initiation at RNA polymerase II promoter] GO:0006468[protein phosphorylation] GO:0006915[apoptotic process] GO:0008285[negative regulation of cell population proliferation] GO:0016251[RNA polymerase II general transcription initiation factor activity] GO:0017162[aryl hydrocarbon receptor binding] GO:0032991[protein-containing complex] GO:0033276[transcription factor TFTC complex] GO:0035521[monoubiquitinated histone deubiquitination] GO:0035522[monoubiquitinated histone H2A deubiquitination] GO:0042789[mRNA transcription by RNA polymerase II] GO:0043966[histone H3 acetylation] GO:0045786[negative regulation of cell cycle] GO:0045893[positive regulation of DNA-templated transcription] GO:0046695[SLIK (SAGA-like) complex] GO:0046982[protein heterodimerization activity] GO:0051123[RNA polymerase II preinitiation complex assembly] GO:0060090[molecular adaptor activity] GO:0060261[positive regulation of transcription initiation by RNA polymerase II] GO:0071339[MLL1 complex]
A4D299 [Target identity:100%; Query identity:100%] TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
Show all
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Disease related genes Human disease related genes Congenital malformations Other congenital malformations Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124[SAGA complex] GO:0003677[DNA binding] GO:0003713[transcription coactivator activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005669[transcription factor TFIID complex] GO:0005829[cytosol] GO:0006282[regulation of DNA repair] GO:0006352[DNA-templated transcription initiation] GO:0006357[regulation of transcription by RNA polymerase II] GO:0006366[transcription by RNA polymerase II] GO:0006367[transcription initiation at RNA polymerase II promoter] GO:0006468[protein phosphorylation] GO:0006915[apoptotic process] GO:0016251[RNA polymerase II general transcription initiation factor activity] GO:0017162[aryl hydrocarbon receptor binding] GO:0032991[protein-containing complex] GO:0033276[transcription factor TFTC complex] GO:0035521[monoubiquitinated histone deubiquitination] GO:0035522[monoubiquitinated histone H2A deubiquitination] GO:0042789[mRNA transcription by RNA polymerase II] GO:0043065[positive regulation of apoptotic process] GO:0043966[histone H3 acetylation] GO:0045786[negative regulation of cell cycle] GO:0045893[positive regulation of DNA-templated transcription] GO:0046695[SLIK (SAGA-like) complex] GO:0046982[protein heterodimerization activity] GO:0051123[RNA polymerase II preinitiation complex assembly] GO:0060090[molecular adaptor activity] GO:0060261[positive regulation of transcription initiation by RNA polymerase II] GO:0071339[MLL1 complex]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Disease related genes Human disease related genes Congenital malformations Other congenital malformations Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124[SAGA complex] GO:0003677[DNA binding] GO:0003713[transcription coactivator activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005669[transcription factor TFIID complex] GO:0005829[cytosol] GO:0006282[regulation of DNA repair] GO:0006352[DNA-templated transcription initiation] GO:0006357[regulation of transcription by RNA polymerase II] GO:0006366[transcription by RNA polymerase II] GO:0006367[transcription initiation at RNA polymerase II promoter] GO:0006468[protein phosphorylation] GO:0006915[apoptotic process] GO:0008285[negative regulation of cell population proliferation] GO:0016251[RNA polymerase II general transcription initiation factor activity] GO:0017162[aryl hydrocarbon receptor binding] GO:0032991[protein-containing complex] GO:0033276[transcription factor TFTC complex] GO:0035521[monoubiquitinated histone deubiquitination] GO:0035522[monoubiquitinated histone H2A deubiquitination] GO:0042789[mRNA transcription by RNA polymerase II] GO:0043966[histone H3 acetylation] GO:0045786[negative regulation of cell cycle] GO:0045893[positive regulation of DNA-templated transcription] GO:0046695[SLIK (SAGA-like) complex] GO:0046982[protein heterodimerization activity] GO:0051123[RNA polymerase II preinitiation complex assembly] GO:0060090[molecular adaptor activity] GO:0060261[positive regulation of transcription initiation by RNA polymerase II] GO:0071339[MLL1 complex]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Disease related genes Human disease related genes Congenital malformations Other congenital malformations Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124[SAGA complex] GO:0003677[DNA binding] GO:0003713[transcription coactivator activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005669[transcription factor TFIID complex] GO:0005829[cytosol] GO:0006282[regulation of DNA repair] GO:0006352[DNA-templated transcription initiation] GO:0006357[regulation of transcription by RNA polymerase II] GO:0006366[transcription by RNA polymerase II] GO:0006367[transcription initiation at RNA polymerase II promoter] GO:0006468[protein phosphorylation] GO:0006915[apoptotic process] GO:0008285[negative regulation of cell population proliferation] GO:0016251[RNA polymerase II general transcription initiation factor activity] GO:0017162[aryl hydrocarbon receptor binding] GO:0032991[protein-containing complex] GO:0033276[transcription factor TFTC complex] GO:0035521[monoubiquitinated histone deubiquitination] GO:0035522[monoubiquitinated histone H2A deubiquitination] GO:0042789[mRNA transcription by RNA polymerase II] GO:0043966[histone H3 acetylation] GO:0045786[negative regulation of cell cycle] GO:0045893[positive regulation of DNA-templated transcription] GO:0046695[SLIK (SAGA-like) complex] GO:0046982[protein heterodimerization activity] GO:0051123[RNA polymerase II preinitiation complex assembly] GO:0060090[molecular adaptor activity] GO:0060261[positive regulation of transcription initiation by RNA polymerase II] GO:0071339[MLL1 complex]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Disease related genes Human disease related genes Congenital malformations Other congenital malformations Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124[SAGA complex] GO:0003677[DNA binding] GO:0003713[transcription coactivator activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005669[transcription factor TFIID complex] GO:0005829[cytosol] GO:0006282[regulation of DNA repair] GO:0006352[DNA-templated transcription initiation] GO:0006357[regulation of transcription by RNA polymerase II] GO:0006366[transcription by RNA polymerase II] GO:0006367[transcription initiation at RNA polymerase II promoter] GO:0006468[protein phosphorylation] GO:0006915[apoptotic process] GO:0008285[negative regulation of cell population proliferation] GO:0016251[RNA polymerase II general transcription initiation factor activity] GO:0017162[aryl hydrocarbon receptor binding] GO:0032991[protein-containing complex] GO:0033276[transcription factor TFTC complex] GO:0035521[monoubiquitinated histone deubiquitination] GO:0035522[monoubiquitinated histone H2A deubiquitination] GO:0042789[mRNA transcription by RNA polymerase II] GO:0043966[histone H3 acetylation] GO:0045786[negative regulation of cell cycle] GO:0045893[positive regulation of DNA-templated transcription] GO:0046695[SLIK (SAGA-like) complex] GO:0046982[protein heterodimerization activity] GO:0051123[RNA polymerase II preinitiation complex assembly] GO:0060090[molecular adaptor activity] GO:0060261[positive regulation of transcription initiation by RNA polymerase II] GO:0071339[MLL1 complex]
A4D299 [Target identity:100%; Query identity:100%] TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
Show all
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Disease related genes Human disease related genes Congenital malformations Other congenital malformations Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124[SAGA complex] GO:0003677[DNA binding] GO:0003713[transcription coactivator activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005669[transcription factor TFIID complex] GO:0005829[cytosol] GO:0006282[regulation of DNA repair] GO:0006352[DNA-templated transcription initiation] GO:0006357[regulation of transcription by RNA polymerase II] GO:0006366[transcription by RNA polymerase II] GO:0006367[transcription initiation at RNA polymerase II promoter] GO:0006468[protein phosphorylation] GO:0006915[apoptotic process] GO:0016251[RNA polymerase II general transcription initiation factor activity] GO:0017162[aryl hydrocarbon receptor binding] GO:0032991[protein-containing complex] GO:0033276[transcription factor TFTC complex] GO:0035521[monoubiquitinated histone deubiquitination] GO:0035522[monoubiquitinated histone H2A deubiquitination] GO:0042789[mRNA transcription by RNA polymerase II] GO:0043065[positive regulation of apoptotic process] GO:0043966[histone H3 acetylation] GO:0045786[negative regulation of cell cycle] GO:0045893[positive regulation of DNA-templated transcription] GO:0046695[SLIK (SAGA-like) complex] GO:0046982[protein heterodimerization activity] GO:0051123[RNA polymerase II preinitiation complex assembly] GO:0060090[molecular adaptor activity] GO:0060261[positive regulation of transcription initiation by RNA polymerase II] GO:0071339[MLL1 complex]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Human disease related genes Congenital malformations Other congenital malformations Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124[SAGA complex] GO:0005634[nucleus] GO:0005669[transcription factor TFIID complex] GO:0006367[transcription initiation at RNA polymerase II promoter] GO:0016251[RNA polymerase II general transcription initiation factor activity] GO:0046695[SLIK (SAGA-like) complex] GO:0046982[protein heterodimerization activity]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Disease related genes Human disease related genes Congenital malformations Other congenital malformations Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
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GO:0000124[SAGA complex] GO:0003677[DNA binding] GO:0003713[transcription coactivator activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005669[transcription factor TFIID complex] GO:0005829[cytosol] GO:0006282[regulation of DNA repair] GO:0006352[DNA-templated transcription initiation] GO:0006357[regulation of transcription by RNA polymerase II] GO:0006366[transcription by RNA polymerase II] GO:0006367[transcription initiation at RNA polymerase II promoter] GO:0006468[protein phosphorylation] GO:0006915[apoptotic process] GO:0008285[negative regulation of cell population proliferation] GO:0016251[RNA polymerase II general transcription initiation factor activity] GO:0017162[aryl hydrocarbon receptor binding] GO:0032991[protein-containing complex] GO:0033276[transcription factor TFTC complex] GO:0035521[monoubiquitinated histone deubiquitination] GO:0035522[monoubiquitinated histone H2A deubiquitination] GO:0042789[mRNA transcription by RNA polymerase II] GO:0043966[histone H3 acetylation] GO:0045786[negative regulation of cell cycle] GO:0045893[positive regulation of DNA-templated transcription] GO:0046695[SLIK (SAGA-like) complex] GO:0046982[protein heterodimerization activity] GO:0051123[RNA polymerase II preinitiation complex assembly] GO:0060090[molecular adaptor activity] GO:0060261[positive regulation of transcription initiation by RNA polymerase II] GO:0071339[MLL1 complex]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Disease related genes Human disease related genes Congenital malformations Other congenital malformations Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
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GO:0000124[SAGA complex] GO:0003677[DNA binding] GO:0003713[transcription coactivator activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005669[transcription factor TFIID complex] GO:0005829[cytosol] GO:0006282[regulation of DNA repair] GO:0006352[DNA-templated transcription initiation] GO:0006357[regulation of transcription by RNA polymerase II] GO:0006366[transcription by RNA polymerase II] GO:0006367[transcription initiation at RNA polymerase II promoter] GO:0006468[protein phosphorylation] GO:0006915[apoptotic process] GO:0008285[negative regulation of cell population proliferation] GO:0016251[RNA polymerase II general transcription initiation factor activity] GO:0017162[aryl hydrocarbon receptor binding] GO:0032991[protein-containing complex] GO:0033276[transcription factor TFTC complex] GO:0035521[monoubiquitinated histone deubiquitination] GO:0035522[monoubiquitinated histone H2A deubiquitination] GO:0042789[mRNA transcription by RNA polymerase II] GO:0043966[histone H3 acetylation] GO:0045786[negative regulation of cell cycle] GO:0045893[positive regulation of DNA-templated transcription] GO:0046695[SLIK (SAGA-like) complex] GO:0046982[protein heterodimerization activity] GO:0051123[RNA polymerase II preinitiation complex assembly] GO:0060090[molecular adaptor activity] GO:0060261[positive regulation of transcription initiation by RNA polymerase II] GO:0071339[MLL1 complex]
A4D299 [Target identity:100%; Query identity:100%] TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
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Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Disease related genes Human disease related genes Congenital malformations Other congenital malformations Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124[SAGA complex] GO:0003677[DNA binding] GO:0003713[transcription coactivator activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005669[transcription factor TFIID complex] GO:0005829[cytosol] GO:0006282[regulation of DNA repair] GO:0006352[DNA-templated transcription initiation] GO:0006357[regulation of transcription by RNA polymerase II] GO:0006366[transcription by RNA polymerase II] GO:0006367[transcription initiation at RNA polymerase II promoter] GO:0006468[protein phosphorylation] GO:0006915[apoptotic process] GO:0016251[RNA polymerase II general transcription initiation factor activity] GO:0017162[aryl hydrocarbon receptor binding] GO:0032991[protein-containing complex] GO:0033276[transcription factor TFTC complex] GO:0035521[monoubiquitinated histone deubiquitination] GO:0035522[monoubiquitinated histone H2A deubiquitination] GO:0042789[mRNA transcription by RNA polymerase II] GO:0043065[positive regulation of apoptotic process] GO:0043966[histone H3 acetylation] GO:0045786[negative regulation of cell cycle] GO:0045893[positive regulation of DNA-templated transcription] GO:0046695[SLIK (SAGA-like) complex] GO:0046982[protein heterodimerization activity] GO:0051123[RNA polymerase II preinitiation complex assembly] GO:0060090[molecular adaptor activity] GO:0060261[positive regulation of transcription initiation by RNA polymerase II] GO:0071339[MLL1 complex]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Disease related genes Human disease related genes Congenital malformations Other congenital malformations Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124[SAGA complex] GO:0003677[DNA binding] GO:0003713[transcription coactivator activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005669[transcription factor TFIID complex] GO:0005829[cytosol] GO:0006282[regulation of DNA repair] GO:0006352[DNA-templated transcription initiation] GO:0006357[regulation of transcription by RNA polymerase II] GO:0006366[transcription by RNA polymerase II] GO:0006367[transcription initiation at RNA polymerase II promoter] GO:0006468[protein phosphorylation] GO:0006915[apoptotic process] GO:0008285[negative regulation of cell population proliferation] GO:0016251[RNA polymerase II general transcription initiation factor activity] GO:0017162[aryl hydrocarbon receptor binding] GO:0032991[protein-containing complex] GO:0033276[transcription factor TFTC complex] GO:0035521[monoubiquitinated histone deubiquitination] GO:0035522[monoubiquitinated histone H2A deubiquitination] GO:0042789[mRNA transcription by RNA polymerase II] GO:0043966[histone H3 acetylation] GO:0045786[negative regulation of cell cycle] GO:0045893[positive regulation of DNA-templated transcription] GO:0046695[SLIK (SAGA-like) complex] GO:0046982[protein heterodimerization activity] GO:0051123[RNA polymerase II preinitiation complex assembly] GO:0060090[molecular adaptor activity] GO:0060261[positive regulation of transcription initiation by RNA polymerase II] GO:0071339[MLL1 complex]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Human disease related genes Congenital malformations Other congenital malformations Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124[SAGA complex] GO:0005634[nucleus] GO:0005669[transcription factor TFIID complex] GO:0006367[transcription initiation at RNA polymerase II promoter] GO:0016251[RNA polymerase II general transcription initiation factor activity] GO:0046695[SLIK (SAGA-like) complex] GO:0046982[protein heterodimerization activity]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Disease related genes Human disease related genes Congenital malformations Other congenital malformations Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124[SAGA complex] GO:0003677[DNA binding] GO:0003713[transcription coactivator activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005669[transcription factor TFIID complex] GO:0005829[cytosol] GO:0006282[regulation of DNA repair] GO:0006352[DNA-templated transcription initiation] GO:0006357[regulation of transcription by RNA polymerase II] GO:0006366[transcription by RNA polymerase II] GO:0006367[transcription initiation at RNA polymerase II promoter] GO:0006468[protein phosphorylation] GO:0006915[apoptotic process] GO:0008285[negative regulation of cell population proliferation] GO:0016251[RNA polymerase II general transcription initiation factor activity] GO:0017162[aryl hydrocarbon receptor binding] GO:0032991[protein-containing complex] GO:0033276[transcription factor TFTC complex] GO:0035521[monoubiquitinated histone deubiquitination] GO:0035522[monoubiquitinated histone H2A deubiquitination] GO:0042789[mRNA transcription by RNA polymerase II] GO:0043966[histone H3 acetylation] GO:0045786[negative regulation of cell cycle] GO:0045893[positive regulation of DNA-templated transcription] GO:0046695[SLIK (SAGA-like) complex] GO:0046982[protein heterodimerization activity] GO:0051123[RNA polymerase II preinitiation complex assembly] GO:0060090[molecular adaptor activity] GO:0060261[positive regulation of transcription initiation by RNA polymerase II] GO:0071339[MLL1 complex]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Disease related genes Human disease related genes Congenital malformations Other congenital malformations Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124[SAGA complex] GO:0003677[DNA binding] GO:0003713[transcription coactivator activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005669[transcription factor TFIID complex] GO:0005829[cytosol] GO:0006282[regulation of DNA repair] GO:0006352[DNA-templated transcription initiation] GO:0006357[regulation of transcription by RNA polymerase II] GO:0006366[transcription by RNA polymerase II] GO:0006367[transcription initiation at RNA polymerase II promoter] GO:0006468[protein phosphorylation] GO:0006915[apoptotic process] GO:0008285[negative regulation of cell population proliferation] GO:0016251[RNA polymerase II general transcription initiation factor activity] GO:0017162[aryl hydrocarbon receptor binding] GO:0032991[protein-containing complex] GO:0033276[transcription factor TFTC complex] GO:0035521[monoubiquitinated histone deubiquitination] GO:0035522[monoubiquitinated histone H2A deubiquitination] GO:0042789[mRNA transcription by RNA polymerase II] GO:0043966[histone H3 acetylation] GO:0045786[negative regulation of cell cycle] GO:0045893[positive regulation of DNA-templated transcription] GO:0046695[SLIK (SAGA-like) complex] GO:0046982[protein heterodimerization activity] GO:0051123[RNA polymerase II preinitiation complex assembly] GO:0060090[molecular adaptor activity] GO:0060261[positive regulation of transcription initiation by RNA polymerase II] GO:0071339[MLL1 complex]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Disease related genes Human disease related genes Congenital malformations Other congenital malformations Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124[SAGA complex] GO:0003677[DNA binding] GO:0003713[transcription coactivator activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005669[transcription factor TFIID complex] GO:0005829[cytosol] GO:0006282[regulation of DNA repair] GO:0006352[DNA-templated transcription initiation] GO:0006357[regulation of transcription by RNA polymerase II] GO:0006366[transcription by RNA polymerase II] GO:0006367[transcription initiation at RNA polymerase II promoter] GO:0006468[protein phosphorylation] GO:0006915[apoptotic process] GO:0008285[negative regulation of cell population proliferation] GO:0016251[RNA polymerase II general transcription initiation factor activity] GO:0017162[aryl hydrocarbon receptor binding] GO:0032991[protein-containing complex] GO:0033276[transcription factor TFTC complex] GO:0035521[monoubiquitinated histone deubiquitination] GO:0035522[monoubiquitinated histone H2A deubiquitination] GO:0042789[mRNA transcription by RNA polymerase II] GO:0043966[histone H3 acetylation] GO:0045786[negative regulation of cell cycle] GO:0045893[positive regulation of DNA-templated transcription] GO:0046695[SLIK (SAGA-like) complex] GO:0046982[protein heterodimerization activity] GO:0051123[RNA polymerase II preinitiation complex assembly] GO:0060090[molecular adaptor activity] GO:0060261[positive regulation of transcription initiation by RNA polymerase II] GO:0071339[MLL1 complex]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Human disease related genes Congenital malformations Other congenital malformations Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124[SAGA complex] GO:0005634[nucleus] GO:0005669[transcription factor TFIID complex] GO:0006367[transcription initiation at RNA polymerase II promoter] GO:0016251[RNA polymerase II general transcription initiation factor activity] GO:0046695[SLIK (SAGA-like) complex] GO:0046982[protein heterodimerization activity]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Disease related genes Human disease related genes Congenital malformations Other congenital malformations Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124[SAGA complex] GO:0003677[DNA binding] GO:0003713[transcription coactivator activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005669[transcription factor TFIID complex] GO:0005829[cytosol] GO:0006282[regulation of DNA repair] GO:0006352[DNA-templated transcription initiation] GO:0006357[regulation of transcription by RNA polymerase II] GO:0006366[transcription by RNA polymerase II] GO:0006367[transcription initiation at RNA polymerase II promoter] GO:0006468[protein phosphorylation] GO:0006915[apoptotic process] GO:0008285[negative regulation of cell population proliferation] GO:0016251[RNA polymerase II general transcription initiation factor activity] GO:0017162[aryl hydrocarbon receptor binding] GO:0032991[protein-containing complex] GO:0033276[transcription factor TFTC complex] GO:0035521[monoubiquitinated histone deubiquitination] GO:0035522[monoubiquitinated histone H2A deubiquitination] GO:0042789[mRNA transcription by RNA polymerase II] GO:0043966[histone H3 acetylation] GO:0045786[negative regulation of cell cycle] GO:0045893[positive regulation of DNA-templated transcription] GO:0046695[SLIK (SAGA-like) complex] GO:0046982[protein heterodimerization activity] GO:0051123[RNA polymerase II preinitiation complex assembly] GO:0060090[molecular adaptor activity] GO:0060261[positive regulation of transcription initiation by RNA polymerase II] GO:0071339[MLL1 complex]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Human disease related genes Congenital malformations Other congenital malformations Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124[SAGA complex] GO:0005634[nucleus] GO:0005669[transcription factor TFIID complex] GO:0006367[transcription initiation at RNA polymerase II promoter] GO:0016251[RNA polymerase II general transcription initiation factor activity] GO:0046695[SLIK (SAGA-like) complex] GO:0046982[protein heterodimerization activity]
A4D299 [Target identity:100%; Query identity:100%] TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
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Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Disease related genes Human disease related genes Congenital malformations Other congenital malformations Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124[SAGA complex] GO:0003677[DNA binding] GO:0003713[transcription coactivator activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005669[transcription factor TFIID complex] GO:0005829[cytosol] GO:0006282[regulation of DNA repair] GO:0006352[DNA-templated transcription initiation] GO:0006357[regulation of transcription by RNA polymerase II] GO:0006366[transcription by RNA polymerase II] GO:0006367[transcription initiation at RNA polymerase II promoter] GO:0006468[protein phosphorylation] GO:0006915[apoptotic process] GO:0016251[RNA polymerase II general transcription initiation factor activity] GO:0017162[aryl hydrocarbon receptor binding] GO:0032991[protein-containing complex] GO:0033276[transcription factor TFTC complex] GO:0035521[monoubiquitinated histone deubiquitination] GO:0035522[monoubiquitinated histone H2A deubiquitination] GO:0042789[mRNA transcription by RNA polymerase II] GO:0043065[positive regulation of apoptotic process] GO:0043966[histone H3 acetylation] GO:0045786[negative regulation of cell cycle] GO:0045893[positive regulation of DNA-templated transcription] GO:0046695[SLIK (SAGA-like) complex] GO:0046982[protein heterodimerization activity] GO:0051123[RNA polymerase II preinitiation complex assembly] GO:0060090[molecular adaptor activity] GO:0060261[positive regulation of transcription initiation by RNA polymerase II] GO:0071339[MLL1 complex]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Human disease related genes Congenital malformations Other congenital malformations Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124[SAGA complex] GO:0005634[nucleus] GO:0005669[transcription factor TFIID complex] GO:0006367[transcription initiation at RNA polymerase II promoter] GO:0016251[RNA polymerase II general transcription initiation factor activity] GO:0046695[SLIK (SAGA-like) complex] GO:0046982[protein heterodimerization activity]
A4D299 [Target identity:100%; Query identity:100%] TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
Show all
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Disease related genes Human disease related genes Congenital malformations Other congenital malformations Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124[SAGA complex] GO:0003677[DNA binding] GO:0003713[transcription coactivator activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005669[transcription factor TFIID complex] GO:0005829[cytosol] GO:0006282[regulation of DNA repair] GO:0006352[DNA-templated transcription initiation] GO:0006357[regulation of transcription by RNA polymerase II] GO:0006366[transcription by RNA polymerase II] GO:0006367[transcription initiation at RNA polymerase II promoter] GO:0006468[protein phosphorylation] GO:0006915[apoptotic process] GO:0016251[RNA polymerase II general transcription initiation factor activity] GO:0017162[aryl hydrocarbon receptor binding] GO:0032991[protein-containing complex] GO:0033276[transcription factor TFTC complex] GO:0035521[monoubiquitinated histone deubiquitination] GO:0035522[monoubiquitinated histone H2A deubiquitination] GO:0042789[mRNA transcription by RNA polymerase II] GO:0043065[positive regulation of apoptotic process] GO:0043966[histone H3 acetylation] GO:0045786[negative regulation of cell cycle] GO:0045893[positive regulation of DNA-templated transcription] GO:0046695[SLIK (SAGA-like) complex] GO:0046982[protein heterodimerization activity] GO:0051123[RNA polymerase II preinitiation complex assembly] GO:0060090[molecular adaptor activity] GO:0060261[positive regulation of transcription initiation by RNA polymerase II] GO:0071339[MLL1 complex]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Disease related genes Human disease related genes Congenital malformations Other congenital malformations Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124[SAGA complex] GO:0003677[DNA binding] GO:0003713[transcription coactivator activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005669[transcription factor TFIID complex] GO:0005829[cytosol] GO:0006282[regulation of DNA repair] GO:0006352[DNA-templated transcription initiation] GO:0006357[regulation of transcription by RNA polymerase II] GO:0006366[transcription by RNA polymerase II] GO:0006367[transcription initiation at RNA polymerase II promoter] GO:0006468[protein phosphorylation] GO:0006915[apoptotic process] GO:0008285[negative regulation of cell population proliferation] GO:0016251[RNA polymerase II general transcription initiation factor activity] GO:0017162[aryl hydrocarbon receptor binding] GO:0032991[protein-containing complex] GO:0033276[transcription factor TFTC complex] GO:0035521[monoubiquitinated histone deubiquitination] GO:0035522[monoubiquitinated histone H2A deubiquitination] GO:0042789[mRNA transcription by RNA polymerase II] GO:0043966[histone H3 acetylation] GO:0045786[negative regulation of cell cycle] GO:0045893[positive regulation of DNA-templated transcription] GO:0046695[SLIK (SAGA-like) complex] GO:0046982[protein heterodimerization activity] GO:0051123[RNA polymerase II preinitiation complex assembly] GO:0060090[molecular adaptor activity] GO:0060261[positive regulation of transcription initiation by RNA polymerase II] GO:0071339[MLL1 complex]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Human disease related genes Congenital malformations Other congenital malformations Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124[SAGA complex] GO:0005634[nucleus] GO:0005669[transcription factor TFIID complex] GO:0006367[transcription initiation at RNA polymerase II promoter] GO:0016251[RNA polymerase II general transcription initiation factor activity] GO:0046695[SLIK (SAGA-like) complex] GO:0046982[protein heterodimerization activity]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Disease related genes Human disease related genes Congenital malformations Other congenital malformations Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124[SAGA complex] GO:0003677[DNA binding] GO:0003713[transcription coactivator activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005669[transcription factor TFIID complex] GO:0005829[cytosol] GO:0006282[regulation of DNA repair] GO:0006352[DNA-templated transcription initiation] GO:0006357[regulation of transcription by RNA polymerase II] GO:0006366[transcription by RNA polymerase II] GO:0006367[transcription initiation at RNA polymerase II promoter] GO:0006468[protein phosphorylation] GO:0006915[apoptotic process] GO:0008285[negative regulation of cell population proliferation] GO:0016251[RNA polymerase II general transcription initiation factor activity] GO:0017162[aryl hydrocarbon receptor binding] GO:0032991[protein-containing complex] GO:0033276[transcription factor TFTC complex] GO:0035521[monoubiquitinated histone deubiquitination] GO:0035522[monoubiquitinated histone H2A deubiquitination] GO:0042789[mRNA transcription by RNA polymerase II] GO:0043966[histone H3 acetylation] GO:0045786[negative regulation of cell cycle] GO:0045893[positive regulation of DNA-templated transcription] GO:0046695[SLIK (SAGA-like) complex] GO:0046982[protein heterodimerization activity] GO:0051123[RNA polymerase II preinitiation complex assembly] GO:0060090[molecular adaptor activity] GO:0060261[positive regulation of transcription initiation by RNA polymerase II] GO:0071339[MLL1 complex]
A4D299 [Target identity:100%; Query identity:100%] TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
Show all
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Disease related genes Human disease related genes Congenital malformations Other congenital malformations Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124[SAGA complex] GO:0003677[DNA binding] GO:0003713[transcription coactivator activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005669[transcription factor TFIID complex] GO:0005829[cytosol] GO:0006282[regulation of DNA repair] GO:0006352[DNA-templated transcription initiation] GO:0006357[regulation of transcription by RNA polymerase II] GO:0006366[transcription by RNA polymerase II] GO:0006367[transcription initiation at RNA polymerase II promoter] GO:0006468[protein phosphorylation] GO:0006915[apoptotic process] GO:0016251[RNA polymerase II general transcription initiation factor activity] GO:0017162[aryl hydrocarbon receptor binding] GO:0032991[protein-containing complex] GO:0033276[transcription factor TFTC complex] GO:0035521[monoubiquitinated histone deubiquitination] GO:0035522[monoubiquitinated histone H2A deubiquitination] GO:0042789[mRNA transcription by RNA polymerase II] GO:0043065[positive regulation of apoptotic process] GO:0043966[histone H3 acetylation] GO:0045786[negative regulation of cell cycle] GO:0045893[positive regulation of DNA-templated transcription] GO:0046695[SLIK (SAGA-like) complex] GO:0046982[protein heterodimerization activity] GO:0051123[RNA polymerase II preinitiation complex assembly] GO:0060090[molecular adaptor activity] GO:0060261[positive regulation of transcription initiation by RNA polymerase II] GO:0071339[MLL1 complex]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Disease related genes Human disease related genes Congenital malformations Other congenital malformations Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124[SAGA complex] GO:0003677[DNA binding] GO:0003713[transcription coactivator activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005669[transcription factor TFIID complex] GO:0005829[cytosol] GO:0006282[regulation of DNA repair] GO:0006352[DNA-templated transcription initiation] GO:0006357[regulation of transcription by RNA polymerase II] GO:0006366[transcription by RNA polymerase II] GO:0006367[transcription initiation at RNA polymerase II promoter] GO:0006468[protein phosphorylation] GO:0006915[apoptotic process] GO:0008285[negative regulation of cell population proliferation] GO:0016251[RNA polymerase II general transcription initiation factor activity] GO:0017162[aryl hydrocarbon receptor binding] GO:0032991[protein-containing complex] GO:0033276[transcription factor TFTC complex] GO:0035521[monoubiquitinated histone deubiquitination] GO:0035522[monoubiquitinated histone H2A deubiquitination] GO:0042789[mRNA transcription by RNA polymerase II] GO:0043966[histone H3 acetylation] GO:0045786[negative regulation of cell cycle] GO:0045893[positive regulation of DNA-templated transcription] GO:0046695[SLIK (SAGA-like) complex] GO:0046982[protein heterodimerization activity] GO:0051123[RNA polymerase II preinitiation complex assembly] GO:0060090[molecular adaptor activity] GO:0060261[positive regulation of transcription initiation by RNA polymerase II] GO:0071339[MLL1 complex]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Disease related genes Human disease related genes Congenital malformations Other congenital malformations Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124[SAGA complex] GO:0003677[DNA binding] GO:0003713[transcription coactivator activity] GO:0005515[protein binding] GO:0005634[nucleus] GO:0005654[nucleoplasm] GO:0005669[transcription factor TFIID complex] GO:0005829[cytosol] GO:0006282[regulation of DNA repair] GO:0006352[DNA-templated transcription initiation] GO:0006357[regulation of transcription by RNA polymerase II] GO:0006366[transcription by RNA polymerase II] GO:0006367[transcription initiation at RNA polymerase II promoter] GO:0006468[protein phosphorylation] GO:0006915[apoptotic process] GO:0008285[negative regulation of cell population proliferation] GO:0016251[RNA polymerase II general transcription initiation factor activity] GO:0017162[aryl hydrocarbon receptor binding] GO:0032991[protein-containing complex] GO:0033276[transcription factor TFTC complex] GO:0035521[monoubiquitinated histone deubiquitination] GO:0035522[monoubiquitinated histone H2A deubiquitination] GO:0042789[mRNA transcription by RNA polymerase II] GO:0043966[histone H3 acetylation] GO:0045786[negative regulation of cell cycle] GO:0045893[positive regulation of DNA-templated transcription] GO:0046695[SLIK (SAGA-like) complex] GO:0046982[protein heterodimerization activity] GO:0051123[RNA polymerase II preinitiation complex assembly] GO:0060090[molecular adaptor activity] GO:0060261[positive regulation of transcription initiation by RNA polymerase II] GO:0071339[MLL1 complex]
Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Human disease related genes Congenital malformations Other congenital malformations Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124[SAGA complex] GO:0005634[nucleus] GO:0005669[transcription factor TFIID complex] GO:0006367[transcription initiation at RNA polymerase II promoter] GO:0016251[RNA polymerase II general transcription initiation factor activity] GO:0046695[SLIK (SAGA-like) complex] GO:0046982[protein heterodimerization activity]
The Human Protein Atlas project is funded
