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                                  PATHOLOGY PANCREATIC CANCER Show tissue menu
                                  BREAST CANCER CARCINOID CERVICAL CANCER COLORECTAL CANCER ENDOMETRIAL CANCER GLIOMA HEAD AND NECK CANCER LIVER CANCER LUNG CANCER LYMPHOMA
                                  MELANOMA OVARIAN CANCER PANCREATIC CANCER PROSTATE CANCER RENAL CANCER SKIN CANCER STOMACH CANCER TESTIS CANCER THYROID CANCER UROTHELIAL CANCER
                                  ANTIBODIES
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                                  Pancreatic cancer
                                  Human pathology
                                  Pancreatic cancer
                                  PANCREATIC CANCER - Interactive survival scatter ploti

                                  The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

                                  The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

                                  Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

                                  Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

                                  & Survival analysisi

                                  Kaplan-Meier plots summarize results from analysis of correlation between mRNA expression level and patient survival. Patients were divided based on level of expression into one of the two groups "low" (under cut off) or "high" (over cut off). X-axis shows time for survival (years) and y-axis shows the probability of survival, where 1.0 corresponds to 100 percent.

                                  ENG is not prognostic in pancreatic cancer


                                  Stage:

                                  0 1 2 3 4 5 6 7Time after diagnosis (years)0.0102030405060708090100110120Expression level (FPKM)Dead (n=92)Alive (n=84)41Density dead48Density alive1.0Density dead under cut off1.3Density dead over cut off0.00.20.40.60.81.0P score0.00.20.60.50.40.81.0Medain separation0.3P scoreDead median separationCut off
                                  0.00.10.20.30.40.50.60.70.80.91.0Survival probability 0 1 2 3 4 5 6 7Time (years)Low expression (n=99)High expression (n=77)
                                  Survival analysis
                                  Current cut offi

                                  Current cut-off shows the cut-off (FPKM) currently selected. It may be changed manually. When the current cut-off is changed, the vertical dashed line indicating cut-off, the interactive survival scatter plot and the Kaplan-Meier curve will be automatically adjusted to show results accordingly.

                                  :
                                  Best expression cut offi

                                  Based on the FPKM value of each gene, patients were classified into two groups and association between prognosis (survival) and gene expression (FPKM) was examined. The best expression cut-off refers the FPKM value that yields maximal difference with regard to survival between the two groups at the lowest log-rank P-value. Best expression cut-off was selected based on survival analysis .

                                  When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the best expression cut-off.

                                  : 45.15
                                  Median expressioni

                                  Median expression refers to the median FPKM value calculated based on the gene expression (FPKM) data from all patients in this dataset. When clicking on this number, the vertical dashed line indicating cut-off, the interactive survival plot, and the Kaplan-Meier curve will be adjusted to show results based on the median expression.

                                  : 42.58
                                  Median follow up timei

                                  Median follow up time refers to the median time (years) after diagnosis with this type of cancer, based on clinical data from all patients in this dataset.

                                  : 1.27
                                  P scorei

                                  Log-rank P value for Kaplan-Meier plot showing results from analysis of correlation between mRNA expression level and patient survival.

                                  0.022
                                  5-year survival highi

                                  5-year survival for patients with higher expression than the expression cutoff.

                                  For melanoma and glioma, 3-year survival is shown.

                                  27%
                                  5-year survival lowi

                                  5-year survival for patients with lower expression than the expression cutoff.

                                  For melanoma and glioma, 3-year survival is shown.

                                  27%
                                  TCGA RNA samplesi

                                  RNA-seq data is reported as average FPKM (number Fragments Per Kilobase of exon per Million reads), generated by the The Cancer Genome Atlas (TCGA) .

                                  Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. FPKM values of the individual samples are presented next to the box plot.

                                  Average FPKM 46.2
                                  Number of samples 176
                                  Samples
                                  Sample Description FPKM
                                  TCGA-2J-AABP-01A 58 years, female, white, stage:iib, alive, 463 days 125.8
                                  TCGA-RL-AAAS-01A 60 years, female, white, stage:ib, alive, 9 days 109.0
                                  TCGA-XN-A8T5-01A 53 years, female, white, stage:ib, alive, 720 days 103.0
                                  TCGA-2L-AAQM-01A 52 years, male, white, stage:iib, alive, 1383 days 99.3
                                  TCGA-IB-7652-01A 49 years, female, asian, stage:iib, alive, 1116 days 93.0
                                  TCGA-US-A77J-01A 81 years, female, white, stage:iib, dead, 568 days 90.0
                                  TCGA-IB-AAUS-01A 84 years, female, white, stage:iib, alive, 225 days 89.8
                                  TCGA-IB-AAUR-01A 67 years, male, white, stage:iib, alive, 338 days 89.4
                                  TCGA-3A-A9IL-01A 39 years, female, white, stage:i, alive, 2741 days 87.1
                                  TCGA-XD-AAUH-01A 57 years, female, white, stage:iib, alive, 395 days 85.3
                                  TCGA-HV-A5A4-01A 72 years, female, asian, stage:iia, alive, 232 days 84.2
                                  TCGA-YB-A89D-01A 59 years, male, white, stage:iib, alive, 350 days 83.5
                                  TCGA-IB-7888-01A 66 years, female, black or african american, stage:iia, dead, 1332 days 81.1
                                  TCGA-HZ-7923-01A 65 years, male, white, stage:iia, alive, 314 days 79.0
                                  TCGA-HZ-8001-01A 69 years, male, white, stage:iii, alive, 706 days 77.4
                                  TCGA-H6-A45N-01A 88 years, female, white, stage:iib, dead, 421 days 73.6
                                  TCGA-IB-A5SQ-01A 56 years, female, white, stage:ib, dead, 219 days 71.9
                                  TCGA-3A-A9IN-01A 62 years, female, white, stage:ib, alive, 2084 days 71.2
                                  TCGA-HZ-A4BH-01A 75 years, male, white, stage:iib, alive, 194 days 71.1
                                  TCGA-3A-A9IX-01A 40 years, male, white, stage:ia, alive, 1037 days 70.7
                                  TCGA-IB-7651-01A 64 years, female, white, stage:iib, dead, 603 days 70.4
                                  TCGA-2J-AAB9-01A 71 years, female, white, stage:iib, dead, 627 days 70.3
                                  TCGA-Q3-A5QY-01A 58 years, male, white, stage:iib, alive, 416 days 69.5
                                  TCGA-F2-7273-01A 54 years, male, black or african american, stage:iib, dead, 592 days 67.7
                                  TCGA-IB-AAUW-01A 63 years, female, white, stage:iib, dead, 230 days 67.5
                                  TCGA-IB-7897-01A 54 years, female, white, stage:iib, dead, 486 days 67.1
                                  TCGA-2L-AAQL-01A 82 years, male, white, stage:iib, dead, 292 days 67.0
                                  TCGA-IB-7649-01A 73 years, female, stage:iib, dead, 467 days 66.4
                                  TCGA-IB-AAUV-01A 49 years, male, white, stage:iib, alive, 404 days 66.0
                                  TCGA-S4-A8RP-01A 77 years, female, white, stage:iib, dead, 702 days 64.7
                                  TCGA-3E-AAAY-01A 67 years, male, white, stage:iib, alive, 2285 days 64.4
                                  TCGA-2J-AABR-01A 60 years, female, white, stage:iia, alive, 438 days 63.8
                                  TCGA-HV-AA8V-01A 50 years, male, asian, stage:iib, alive, 920 days 63.8
                                  TCGA-2J-AABF-01A 73 years, male, white, stage:iib, dead, 691 days 62.9
                                  TCGA-HZ-A77Q-01A 55 years, female, white, stage:iib, alive, 33 days 62.8
                                  TCGA-IB-7889-01A 86 years, female, white, stage:iib, dead, 481 days 61.4
                                  TCGA-FB-AAPS-01A 62 years, female, white, stage:iib, alive, 228 days 61.0
                                  TCGA-IB-AAUT-01A 65 years, male, white, stage:iib, alive, 287 days 60.9
                                  TCGA-IB-7645-01A 44 years, female, stage:iib, dead, 1502 days 60.4
                                  TCGA-US-A774-01A 76 years, female, white, stage:iib, dead, 695 days 60.3
                                  TCGA-HZ-8636-01A 58 years, female, white, stage:iv, dead, 545 days 59.3
                                  TCGA-F2-A44H-01A 65 years, male, white, stage:iia, alive, 586 days 59.3
                                  TCGA-IB-A5SO-01A 71 years, male, white, stage:iib, dead, 365 days 59.2
                                  TCGA-HV-A5A5-01A 61 years, female, asian, stage:iib, alive, 289 days 58.8
                                  TCGA-XD-AAUG-01A 66 years, female, white, stage:iv, alive, 420 days 58.8
                                  TCGA-IB-A5ST-01A 64 years, female, white, stage:iib, alive, 635 days 58.7
                                  TCGA-RB-A7B8-01A 81 years, female, white, stage:iib, dead, 466 days 58.6
                                  TCGA-Z5-AAPL-01A 74 years, female, white, stage:iia, alive, 467 days 58.5
                                  TCGA-F2-7276-01A 64 years, male, white, stage:iib, dead, 216 days 58.5
                                  TCGA-FB-A4P6-01A 54 years, male, white, stage:iib, alive, 767 days 58.1
                                  TCGA-FB-A4P5-01A 69 years, female, white, stage:iib, dead, 179 days 58.0
                                  TCGA-XN-A8T3-01A 67 years, male, white, stage:ib, alive, 951 days 56.5
                                  TCGA-HZ-A49G-01A 58 years, female, white, stage:iib, alive, 660 days 56.4
                                  TCGA-IB-7891-01A 49 years, female, white, stage:iib, dead, 913 days 55.9
                                  TCGA-HZ-7920-01A 71 years, male, white, stage:ib, dead, 236 days 55.6
                                  TCGA-HZ-A49I-01A 77 years, male, white, stage:iib, dead, 308 days 55.3
                                  TCGA-2J-AAB4-01A 48 years, male, white, stage:iib, alive, 729 days 55.0
                                  TCGA-FB-A5VM-01A 74 years, male, white, stage:ib, dead, 498 days 53.5
                                  TCGA-IB-AAUQ-01A 50 years, male, white, stage:iib, dead, 183 days 53.4
                                  TCGA-IB-7885-01A 78 years, female, white, stage:iib, alive, 1257 days 53.1
                                  TCGA-2J-AAB6-01A 75 years, male, white, stage:iia, dead, 293 days 52.9
                                  TCGA-HZ-A4BK-01A 72 years, male, white, stage:iib, alive, 657 days 52.8
                                  TCGA-IB-AAUP-01A 68 years, male, white, stage:iib, alive, 431 days 52.6
                                  TCGA-HZ-8519-01A 73 years, male, white, stage:ia, alive, 454 days 52.2
                                  TCGA-RB-AA9M-01A 43 years, male, white, stage:iib, alive, 286 days 52.1
                                  TCGA-IB-A5SS-01A 64 years, female, white, stage:iib, dead, 460 days 51.4
                                  TCGA-H8-A6C1-01A 53 years, male, white, stage:iia, alive, 671 days 51.2
                                  TCGA-OE-A75W-01A 75 years, male, white, stage:iia, dead, 267 days 50.7
                                  TCGA-FB-A7DR-01A 48 years, male, asian, stage:iia, dead, 353 days 50.6
                                  TCGA-HZ-A9TJ-01A 70 years, male, white, stage:iv, alive, 603 days 50.1
                                  TCGA-HZ-A49H-01A 68 years, female, white, stage:iib, alive, 491 days 49.3
                                  TCGA-HZ-A77P-01A 77 years, male, white, stage:iib, alive, 330 days 49.3
                                  TCGA-HZ-8637-01A 76 years, female, white, stage:iib, dead, 517 days 47.2
                                  TCGA-HZ-8002-01A 61 years, male, white, stage:iib, dead, 366 days 46.6
                                  TCGA-HZ-7918-01A 72 years, male, white, stage:iib, alive, 969 days 46.3
                                  TCGA-2J-AABE-01A 73 years, male, white, stage:iia, alive, 676 days 46.3
                                  TCGA-YH-A8SY-01A 73 years, female, white, alive, 388 days 45.9
                                  TCGA-3A-A9IB-01A 69 years, female, white, stage:iib, dead, 224 days 44.4
                                  TCGA-FB-AAPY-01A 71 years, male, white, stage:iib, dead, 1059 days 44.4
                                  TCGA-HZ-8315-01A 54 years, female, white, stage:iia, dead, 299 days 44.4
                                  TCGA-3A-A9IC-01A 61 years, female, white, stage:iib, dead, 738 days 44.3
                                  TCGA-IB-7890-01A 73 years, male, stage:ib, dead, 598 days 44.2
                                  TCGA-HZ-7925-01A 66 years, male, white, stage:iib, dead, 614 days 44.2
                                  TCGA-3A-A9I9-01A 67 years, male, white, stage:iia, dead, 634 days 43.2
                                  TCGA-HV-AA8X-01A 75 years, female, asian, stage:iib, dead, 532 days 43.2
                                  TCGA-2L-AAQJ-01A 49 years, female, white, stage:iii, dead, 394 days 43.1
                                  TCGA-HZ-7919-01A 52 years, female, white, stage:iib, dead, 593 days 43.1
                                  TCGA-FB-AAPZ-01A 54 years, male, white, stage:iib, alive, 716 days 42.8
                                  TCGA-HZ-8317-01A 69 years, female, white, stage:iib, dead, 378 days 42.4
                                  TCGA-XD-AAUL-01A 56 years, male, white, stage:iia, alive, 498 days 42.0
                                  TCGA-FB-A545-01A 72 years, female, white, stage:iib, dead, 732 days 42.0
                                  TCGA-2L-AAQE-01A 56 years, male, white, stage:iib, dead, 684 days 41.9
                                  TCGA-2J-AAB1-01A 65 years, male, white, stage:iib, dead, 66 days 41.5
                                  TCGA-IB-8127-01A 59 years, male, white, stage:iib, alive, 522 days 41.2
                                  TCGA-FB-AAQ1-01A 49 years, male, white, stage:iib, dead, 123 days 40.4
                                  TCGA-FB-AAQ6-01A 85 years, male, white, stage:ia, dead, 244 days 40.2
                                  TCGA-2L-AAQI-01A 66 years, male, white, stage:iib, dead, 103 days 40.2
                                  TCGA-2J-AABA-01A 55 years, male, white, stage:iib, dead, 607 days 40.0
                                  TCGA-IB-7654-01A 80 years, male, white, stage:iib, dead, 476 days 39.4
                                  TCGA-F2-A8YN-01A 76 years, male, white, stage:iia, alive, 517 days 39.2
                                  TCGA-IB-AAUU-01A 35 years, male, white, stage:iib, alive, 245 days 39.1
                                  TCGA-LB-A8F3-01A 64 years, female, black or african american, stage:iia, alive, 379 days 39.0
                                  TCGA-HZ-7922-01A 61 years, female, white, stage:iib, alive, 4 days 38.6
                                  TCGA-XD-AAUI-01A 50 years, female, white, stage:iib, dead, 366 days 38.5
                                  TCGA-HV-A5A6-01A 65 years, female, asian, stage:iib, dead, 2036 days 37.7
                                  TCGA-F2-A7TX-01A 77 years, male, white, stage:iib, dead, 95 days 37.6
                                  TCGA-US-A77E-01A 73 years, male, white, stage:iib, dead, 430 days 37.6
                                  TCGA-2J-AABT-01A 72 years, female, white, stage:iib, alive, 319 days 37.6
                                  TCGA-LB-A9Q5-01A 63 years, female, white, stage:iib, dead, 313 days 36.6
                                  TCGA-IB-AAUN-01A 74 years, female, white, stage:ib, dead, 144 days 36.5
                                  TCGA-FB-A78T-01A 71 years, female, white, stage:iib, dead, 375 days 36.1
                                  TCGA-2J-AAB8-01A 71 years, male, white, stage:iib, alive, 80 days 36.0
                                  TCGA-3E-AAAZ-01A 71 years, male, white, stage:iia, dead, 2182 days 35.6
                                  TCGA-2J-AABO-01A 43 years, male, white, stage:iib, alive, 440 days 35.5
                                  TCGA-PZ-A5RE-01A 44 years, female, white, stage:iib, dead, 470 days 35.4
                                  TCGA-HZ-7926-01A 57 years, male, black or african american, stage:iib, dead, 518 days 33.7
                                  TCGA-3A-A9IH-01A 66 years, female, white, stage:ia, alive, 1021 days 33.6
                                  TCGA-IB-7644-01A 65 years, female, white, stage:iv, dead, 394 days 33.4
                                  TCGA-IB-8126-01A 80 years, female, white, stage:iii, alive, 462 days 33.1
                                  TCGA-IB-A6UF-01A 63 years, male, white, stage:iib, alive, 666 days 32.5
                                  TCGA-IB-AAUM-01A 76 years, male, white, stage:iib, alive, 8 days 32.2
                                  TCGA-3A-A9IU-01A 65 years, male, white, stage:iib, dead, 458 days 32.0
                                  TCGA-2J-AABH-01A 61 years, male, white, stage:iia, alive, 1287 days 31.7
                                  TCGA-IB-7887-01A 62 years, female, white, stage:iib, dead, 110 days 31.5
                                  TCGA-M8-A5N4-01A 48 years, female, stage:iia, alive, 584 days 31.4
                                  TCGA-HZ-A8P1-01A 81 years, male, white, stage:ib, alive, 7 days 31.3
                                  TCGA-HZ-A77O-01A 77 years, female, white, stage:iib, dead, 160 days 31.3
                                  TCGA-3A-A9I7-01A 45 years, male, black or african american, stage:iib, alive, 1323 days 31.1
                                  TCGA-HV-A7OL-01A 70 years, male, asian, stage:iia, alive, 252 days 31.0
                                  TCGA-3A-A9J0-01A 75 years, male, white, stage:iib, alive, 743 days 30.8
                                  TCGA-Q3-AA2A-01A 64 years, female, white, stage:ib, alive, 95 days 30.0
                                  TCGA-IB-A5SP-01A 77 years, male, white, stage:iia, alive, 482 days 29.9
                                  TCGA-2L-AAQA-01A 76 years, male, white, stage:iib, dead, 143 days 29.8
                                  TCGA-S4-A8RO-01A 75 years, female, white, stage:iib, alive, 525 days 29.7
                                  TCGA-F2-6879-01A 57 years, male, white, stage:iib, dead, 334 days 29.6
                                  TCGA-3A-A9I5-01A 58 years, male, white, alive, 1794 days 29.5
                                  TCGA-IB-A6UG-01A 65 years, male, white, stage:iib, dead, 41 days 29.5
                                  TCGA-F2-A44G-01A 79 years, female, white, stage:iib, dead, 233 days 29.0
                                  TCGA-HZ-7924-01A 60 years, female, white, stage:iia, alive, 840 days 28.7
                                  TCGA-IB-A7LX-01A 57 years, male, white, stage:iib, dead, 250 days 28.7
                                  TCGA-IB-7886-01A 80 years, male, white, stage:iib, dead, 123 days 28.2
                                  TCGA-HZ-8638-01A 84 years, female, white, stage:ia, dead, 151 days 28.0
                                  TCGA-H6-8124-01A 56 years, female, white, stage:iib, alive, 392 days 28.0
                                  TCGA-HV-A5A3-01A 50 years, male, asian, stage:iia, dead, 128 days 27.7
                                  TCGA-YY-A8LH-01A 61 years, female, white, stage:iib, alive, 2016 days 27.7
                                  TCGA-FB-AAPP-01A 71 years, male, white, stage:iib, dead, 485 days 27.3
                                  TCGA-HZ-8003-01A 65 years, female, white, stage:iib, dead, 596 days 27.0
                                  TCGA-IB-7893-01A 64 years, male, white, stage:iia, dead, 117 days 26.7
                                  TCGA-3A-A9IJ-01A 65 years, male, white, stage:ib, alive, 1854 days 26.2
                                  TCGA-IB-7646-01A 60 years, male, white, stage:iib, dead, 145 days 26.0
                                  TCGA-3A-A9IO-01A 56 years, male, white, alive, 1942 days 25.9
                                  TCGA-2J-AABU-01A 56 years, male, white, stage:iib, dead, 277 days 25.8
                                  TCGA-US-A779-01A 54 years, female, white, stage:iib, dead, 511 days 25.8
                                  TCGA-3A-A9IR-01A 64 years, female, white, stage:ib, alive, 1542 days 25.3
                                  TCGA-S4-A8RM-01A 67 years, male, white, stage:iib, alive, 737 days 25.1
                                  TCGA-FB-AAQ3-01A 65 years, female, white, stage:iib, dead, 31 days 24.6
                                  TCGA-LB-A7SX-01A 74 years, female, black or african american, stage:iib, dead, 393 days 24.6
                                  TCGA-IB-AAUO-01A 64 years, female, white, stage:iib, dead, 239 days 24.1
                                  TCGA-L1-A7W4-01A 48 years, female, white, stage:iib, dead, 278 days 23.8
                                  TCGA-2J-AABK-01A 71 years, male, white, stage:iib, alive, 484 days 23.8
                                  TCGA-HZ-8005-01A 81 years, male, white, stage:iib, dead, 120 days 23.3
                                  TCGA-3A-A9IV-01A 59 years, female, white, stage:ib, alive, 1103 days 22.8
                                  TCGA-3A-A9IZ-01A 47 years, male, white, stage:iib, dead, 308 days 21.9
                                  TCGA-FB-AAQ2-01A 81 years, female, white, stage:iib, dead, 153 days 19.9
                                  TCGA-IB-A7M4-01A 81 years, male, white, stage:iib, alive, 483 days 19.5
                                  TCGA-US-A77G-01A 64 years, male, white, stage:iib, dead, 12 days 19.4
                                  TCGA-US-A776-01A 61 years, male, white, stage:iia, alive, 1216 days 19.3
                                  TCGA-FB-AAQ0-01A 68 years, male, white, stage:iia, dead, 473 days 18.2
                                  TCGA-FB-AAPQ-01A 65 years, male, white, stage:iib, dead, 1130 days 17.8
                                  TCGA-2J-AABI-01A 55 years, female, white, stage:iia, alive, 969 days 17.3
                                  TCGA-HV-A7OP-01A 72 years, male, asian, stage:iib, alive, 978 days 17.2
                                  TCGA-2J-AABV-01A 74 years, male, white, stage:iib, dead, 652 days 15.2
                                  TCGA-FB-AAPU-01A 41 years, female, asian, stage:iia, dead, 381 days 14.7
                                  TCGA-F2-6880-01A 70 years, male, white, stage:iib, alive, 289 days 14.5
                                  TCGA-HZ-7289-01A 77 years, male, white, stage:iib, dead, 661 days 13.1
                                  TCGA-3A-A9IS-01A 67 years, male, white, stage:ib, alive, 998 days 11.8
                                  Show allShow less
                                  29.842.658.811.899.30102030405060708090100110120
                                  29.842.658.811.899.30102030405060708090100110120
                                  PANCREATIC CANCER - Protein expressioni

                                  A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here.

                                  Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.

                                   

                                  Antibody stainingi

                                  Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.

                                  Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.


                                  Antibody HPA011862

                                  Antibody HPA067440

                                  Antibody CAB000096

                                  Antibody CAB072873
                                   Staining
                                    High
                                    Medium
                                    Low
                                    Not detected
                                   Intensity
                                    Strong
                                    Moderate
                                    Weak
                                    Negative
                                   Quantity
                                    >75%
                                    75%-25%
                                    <25%
                                    None
                                   Location
                                    Nuclear
                                    Cytoplasmic/membranous
                                    Cytoplasmic/membranous,nuclear
                                    None
                                  Click images for details

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