We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
PTPN6
SECTIONS
  • TISSUE
  • BRAIN
  • SINGLE CELL TYPE
  • TISSUE CELL TYPE
  • PATHOLOGY
  • DISEASE
  • IMMUNE CELL
  • BLOOD PROTEIN
  • SUBCELLULAR
  • CELL LINE
  • STRUCTURE
  • INTERACTION
ABOUT
  • INTRODUCTION
  • HISTORY
  • ORGANIZATION
  • PUBLICATIONS
  • ANTIBODY SUBMISSION
  • ANTIBODY AVAILABILITY
  • ACKNOWLEDGMENTS
  • CONTACT
NEWS
  • NEWS ARTICLES
  • PRESS ROOM
LEARN
  • DICTIONARY
  • PROTEIN CLASSES
  • PROTEIN EVIDENCE
  • METHODS
  • EDUCATIONAL VIDEOS
DATA
  • DOWNLOADABLE DATA
  • PUBLICATION DATA
  • RELEASE HISTORY
  • SARS-COV-2
HELP
  • ANTIBODY VALIDATION
  • ASSAYS & ANNOTATION
  • DISCLAIMER
  • HELP & FAQ
  • PRIVACY STATEMENT
  • LICENCE & CITATION
Fields »
Search result

Field
Term
Gene name
Class
Subclass
Class
Keyword
Chromosome
External id
Tissue
Cell type
Expression
Patient ID
Tissue
Category
Cluster
Reliability
Brain region
Category
Brain region
Category
Brain region
Category
Cluster
Reliability
Cell type
Category
Cluster
Tissue
Cell type
Enrichment
Cancer
Prognosis
Cancer
Category
Cell type
Category
Cell lineage
Category
Cluster
Annotation
Disease
Location
Searches
Location
Cell line
Type
Phase
Reliability
Cancer type
Category
Cluster
Interacting gene
Number of interactions
Pathway
Category
Score
Score
Score
Validation
Validation
Validation
Validation
Antibodies
Protein structure
In atlas
Column


  • SUMMARY

  • TISSUE

  • BRAIN

  • SINGLE CELL

  • TISSUE CELL

  • PATHOLOGY

  • DISEASE

  • IMMUNE

  • BLOOD

  • SUBCELL

  • CELL LINE

  • STRUCTURE

  • INTERACTION

  • PTPN6
IMMUNE CELL B-CELLS Show tissue menu
B-CELLS DENDRITIC CELLS GRANULOCYTES MONOCYTES NK-CELLS PROGENITORS T-CELLS TOTAL PBMC
Immune cell proteome
B-cells
B-CELLS - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
HPA:652.6 nTPM
Monaco:1147.8 nTPM
Schmiedel:213.0 TPM

B-CELLS - HPA RNA-seqi

The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.

Information about each individual sample is listed below. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples. Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max nTPM 652.6
HPA sample nTPM
Memory B-cell
nTPM: 596.8
Samples: 6

Max nTPM: 826.8
Min nTPM: 378.0
P10809_1017 500.4
P10809_1025 826.8
P10809_1044 378.0
P10809_1063 540.9
P10809_1092 630.5
P10809_1105 704.1
Naive B-cell
nTPM: 652.6
Samples: 6

Max nTPM: 1126.8
Min nTPM: 405.3
P10809_1011 405.3
P10809_1029 626.6
P10809_1048 1126.8
P10809_1067 438.2
P10809_1091 634.8
P10809_1104 684.1

B-CELLS - Monaco RNA-seqi

RNA-Seq data generated by Monaco et al is reported as average nTPM.

The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.

Information about each individual sample is listed below. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples. Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max nTPM 1147.8
Monaco sample nTPM
Exhausted memory B-cell
nTPM: 1082.3
Samples: 4

Max nTPM: 1300.6
Min nTPM: 910.7
RHH5310_R3677 1300.6
RHH5218_R3590 964.9
RHH5247_R3619 910.7
RHH5276_R3648 1152.8
Naive B-cell
nTPM: 767.0
Samples: 4

Max nTPM: 948.1
Min nTPM: 452.3
RHH5308_R3675 948.1
RHH5216_R3588 894.4
RHH5245_R3617 452.3
RHH5274_R3646 773.3
Non-switched memory B-cell
nTPM: 847.0
Samples: 4

Max nTPM: 972.0
Min nTPM: 723.1
RHH5309_R3676 972.0
RHH5217_R3589 751.2
RHH5246_R3618 723.1
RHH5275_R3647 941.6
Plasmablast
nTPM: 551.7
Samples: 4

Max nTPM: 628.3
Min nTPM: 514.9
RHH5312_R3679 536.4
RHH5220_R3592 514.9
RHH5249_R3621 628.3
RHH5278_R3650 527.0
Switched memory B-cell
nTPM: 1147.8
Samples: 4

Max nTPM: 1471.7
Min nTPM: 1013.4
RHH5311_R3678 1471.7
RHH5219_R3591 1013.4
RHH5248_R3620 1081.7
RHH5277_R3649 1024.2

B-CELLS - Schmiedel RNA-seqi

RNA-Seq data generated by Schmiedel et al is reported as average TPM.

The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.

Information about each individual sample is listed below. TPM (transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples. Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. TPM values of the individual samples are presented next to the box plot.

Max TPM 213.0
Schmiedel sample id TPM
Naive B-cell
TPM: 213.0
Samples: 91

Max TPM: 343.8
Min TPM: 47.7
B_CELL_NAIVE_1 343.8
B_CELL_NAIVE_2 326.6
B_CELL_NAIVE_3 312.5
B_CELL_NAIVE_4 303.8
B_CELL_NAIVE_5 303.7
B_CELL_NAIVE_6 300.6
B_CELL_NAIVE_7 297.7
B_CELL_NAIVE_8 296.7
B_CELL_NAIVE_9 295.4
B_CELL_NAIVE_10 292.5
B_CELL_NAIVE_11 291.9
B_CELL_NAIVE_12 288.6
B_CELL_NAIVE_13 280.7
B_CELL_NAIVE_14 278.0
B_CELL_NAIVE_15 273.3
B_CELL_NAIVE_16 273.0
B_CELL_NAIVE_17 270.5
B_CELL_NAIVE_18 269.4
B_CELL_NAIVE_19 267.8
B_CELL_NAIVE_20 266.2
B_CELL_NAIVE_21 263.5
B_CELL_NAIVE_22 257.3
B_CELL_NAIVE_23 256.7
B_CELL_NAIVE_24 252.9
B_CELL_NAIVE_25 252.8
B_CELL_NAIVE_26 252.8
B_CELL_NAIVE_27 252.7
B_CELL_NAIVE_28 251.5
B_CELL_NAIVE_29 248.6
B_CELL_NAIVE_30 247.7
B_CELL_NAIVE_31 246.7
B_CELL_NAIVE_32 245.8
B_CELL_NAIVE_33 244.6
B_CELL_NAIVE_34 243.8
B_CELL_NAIVE_35 240.7
B_CELL_NAIVE_36 240.4
B_CELL_NAIVE_37 239.7
B_CELL_NAIVE_38 239.2
B_CELL_NAIVE_39 236.4
B_CELL_NAIVE_40 232.9
B_CELL_NAIVE_41 232.9
B_CELL_NAIVE_42 228.8
B_CELL_NAIVE_43 228.5
B_CELL_NAIVE_44 228.1
B_CELL_NAIVE_45 227.1
B_CELL_NAIVE_46 226.0
B_CELL_NAIVE_47 225.1
B_CELL_NAIVE_48 224.0
B_CELL_NAIVE_49 223.3
B_CELL_NAIVE_50 222.8
B_CELL_NAIVE_51 213.7
B_CELL_NAIVE_52 212.3
B_CELL_NAIVE_53 210.0
B_CELL_NAIVE_54 209.2
B_CELL_NAIVE_55 207.4
B_CELL_NAIVE_56 206.5
B_CELL_NAIVE_57 205.8
B_CELL_NAIVE_58 203.3
B_CELL_NAIVE_59 202.3
B_CELL_NAIVE_60 199.6
B_CELL_NAIVE_61 197.8
B_CELL_NAIVE_62 192.0
B_CELL_NAIVE_63 192.0
B_CELL_NAIVE_64 186.9
B_CELL_NAIVE_65 183.9
B_CELL_NAIVE_66 178.7
B_CELL_NAIVE_67 177.8
B_CELL_NAIVE_68 174.2
B_CELL_NAIVE_69 173.6
B_CELL_NAIVE_70 170.3
B_CELL_NAIVE_71 167.4
B_CELL_NAIVE_72 164.5
B_CELL_NAIVE_73 155.7
B_CELL_NAIVE_74 151.6
B_CELL_NAIVE_75 151.4
B_CELL_NAIVE_76 150.1
B_CELL_NAIVE_77 148.3
B_CELL_NAIVE_78 139.8
B_CELL_NAIVE_79 131.0
B_CELL_NAIVE_80 123.9
B_CELL_NAIVE_81 122.5
B_CELL_NAIVE_82 117.4
B_CELL_NAIVE_83 114.7
B_CELL_NAIVE_84 111.1
B_CELL_NAIVE_85 94.9
B_CELL_NAIVE_86 85.8
B_CELL_NAIVE_87 75.3
B_CELL_NAIVE_88 70.0
B_CELL_NAIVE_89 63.4
B_CELL_NAIVE_90 57.3
B_CELL_NAIVE_91 47.7
Show allShow less

Contact

  • NEWS ARTICLES
  • PRESS ROOM

The Project

  • INTRODUCTION
  • ORGANIZATION
  • PUBLICATIONS

The Human Protein Atlas

  • DOWNLOADABLE DATA
  • LICENCE & CITATION
  • HELP & FAQ
The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.


contact@proteinatlas.org