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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Medium
Hepatocytes:
Medium
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
43.2
nTPM
HPA:
43.2
nTPM
GTEx:
40.3
nTPM
FANTOM5:
71.4
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA037477
Antibody HPA037478
Cholangiocytes
Low
Medium
Hepatocytes
Medium
Medium
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPM
43.2
Female, age 60
Liver sample 21 nTPM: 35.5
Male, age 54
Liver sample 23 nTPM: 55.6
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 40.5
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 49.6
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 38.1
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 50.2
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 57.1
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 29.8
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 40.3
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 35
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Average nTPM
40.3
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 40.3
Samples: 226
Max nTPM: 108.8
Min nTPM: 19.7
Std nTPM: 13.9
Median nTPM: 37.4
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
108.8
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
103.6
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
88.3
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
81.3
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
80.9
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
78.3
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
76.1
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
75.7
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
72.8
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
72.7
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
68.1
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
65.9
GTEX-14XAO-0226-SM-68728
60-69 years, female
65.6
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
65.5
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
65.3
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
65.1
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
64.4
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
62.6
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
61.9
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
61.2
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
59.3
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
58.3
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
57.7
GTEX-12696-0826-SM-5EGGE
60-69 years, male
57.7
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
57.7
GTEX-13113-1326-SM-5GCOI
60-69 years, female
57.6
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
56.5
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
54.3
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
54.1
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
53.9
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
53.1
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
52.3
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
51.6
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
51.5
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
51.3
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
51.3
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
51.2
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
50.8
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
50.2
GTEX-QESD-2026-SM-447BI
20-29 years, male
49.2
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
49.0
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
48.4
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
48.4
GTEX-14PHX-0526-SM-664NW
50-59 years, male
48.2
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
48.2
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
48.1
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
47.9
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
47.8
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
46.8
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
46.7
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
46.4
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
46.2
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
45.8
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
45.6
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
45.4
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
45.4
GTEX-14JG1-1626-SM-664NH
40-49 years, male
45.2
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
45.2
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
45.0
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
45.0
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
44.9
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
44.6
GTEX-18A7A-1526-SM-72D69
50-59 years, female
44.5
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
44.5
GTEX-P78B-1326-SM-3P611
40-49 years, female
44.4
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
43.7
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
43.5
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
43.5
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
43.2
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
43.1
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
43.0
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
43.0
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
42.0
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
41.8
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
41.6
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
41.2
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
41.2
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
41.0
GTEX-18A66-2026-SM-7189C
60-69 years, male
40.8
GTEX-S32W-1926-SM-4AD63
50-59 years, female
40.8
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
40.7
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
40.3
GTEX-14PJO-1726-SM-68719
60-69 years, male
40.3
GTEX-11ZUS-2526-SM-59872
30-39 years, male
40.2
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
40.2
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
40.2
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
40.2
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
40.1
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
40.0
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
39.9
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
39.8
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
39.7
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
39.7
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
39.6
GTEX-Q734-0326-SM-48U15
40-49 years, female
39.6
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
39.2
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
39.2
GTEX-17HHE-0126-SM-79398
50-59 years, male
39.1
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
39.1
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
39.1
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
39.0
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
38.7
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
38.7
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
38.6
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
38.4
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
38.2
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
38.0
GTEX-1399T-0826-SM-5IFES
60-69 years, male
37.9
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
37.8
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
37.7
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
37.7
GTEX-18465-1626-SM-7LG6N
50-59 years, male
37.6
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
37.5
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
37.4
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
37.1
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
36.8
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
36.8
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
36.2
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
36.1
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
36.0
GTEX-QEL4-1226-SM-447A4
50-59 years, male
36.0
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
36.0
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
35.8
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
35.7
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
35.4
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
35.4
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
35.3
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
35.3
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
35.3
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
35.1
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
35.1
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
35.1
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
35.1
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
35.1
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
35.1
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
35.0
GTEX-14E7W-1526-SM-6871X
70-79 years, male
34.8
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
34.7
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
34.6
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
34.4
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
34.2
GTEX-O5YV-0726-SM-EV798
60-69 years, female
34.1
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
33.8
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
33.7
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
33.6
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
33.3
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
33.2
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
32.9
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
32.9
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
32.8
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
32.5
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
32.4
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
32.3
GTEX-RN64-1826-SM-48FDV
50-59 years, male
32.3
GTEX-1B932-1426-SM-793AN
40-49 years, female
32.2
GTEX-1B933-1226-SM-731DW
50-59 years, female
32.2
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
32.2
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
32.2
GTEX-R53T-0326-SM-48FEC
50-59 years, female
32.1
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
32.1
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
32.0
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
31.9
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
31.8
GTEX-144GL-1426-SM-79OMA
50-59 years, male
31.7
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
31.7
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
31.6
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
31.6
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
31.6
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
31.2
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
31.2
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
31.1
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
31.0
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
30.8
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
30.7
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
30.6
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
30.5
GTEX-RU72-1426-SM-46MUF
50-59 years, female
30.4
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
30.4
GTEX-17F96-1226-SM-79OK2
70-79 years, male
30.3
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
30.1
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
30.1
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
30.1
GTEX-13112-1426-SM-5EGH8
50-59 years, male
29.9
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
29.9
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
29.8
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
29.6
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
29.5
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
29.3
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
29.3
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
29.3
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
29.1
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
28.9
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
28.9
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
28.8
GTEX-11GSP-0626-SM-5986T
60-69 years, female
28.6
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
28.3
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
27.8
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
27.6
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
27.5
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
27.5
GTEX-S33H-1626-SM-4AD68
30-39 years, male
27.4
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
27.2
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
27.1
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
27.0
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
26.9
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
26.6
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
26.5
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
26.3
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
26.2
GTEX-REY6-1226-SM-48FDR
60-69 years, male
25.4
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
25.4
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
25.3
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
24.9
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
24.5
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
24.5
GTEX-X261-1726-SM-4PQYT
50-59 years, male
24.1
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
24.0
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
23.7
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
23.6
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
22.9
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
22.6
GTEX-YECK-1926-SM-4W21H
60-69 years, male
22.5
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
22.1
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
21.4
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
21.3
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
19.7
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
The Human Protein Atlas project is funded
