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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA035231
Moderate to strong nuclear immunoreactivity was observed in gastro intestinal glands and renal tubules. Hepatocytes, pancreas and gallbladder showed weak nuclear staining. Strong cytoplasmic positivity was exhibited in placental trophoblastic cells and skeletal myocytes while myoepithlial cells of breast and smooth muscle cells were moderately stained. Remaining normal tissues were mainly negative.
CAB010430
Gastrointestinal tract, pancreas, urinary bladder, gall bladder, testis and cells in renal tubuli showed moderate to strong nuclear positivity. Purkinje cells showed moderate cytoplasmic and nuclear stained. Hepatocytes were weakly stained. Remaining normal tissues were mainly negative.