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SPDYE1
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  • SPDYE1
PROTEIN SUMMARY SECTION OVERVIEW GENE INFORMATION RNA DATA ANTIBODY DATA
GENERAL INFORMATIONi

General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.

Gene namei

Official gene symbol, which is typically a short form of the gene name, according to HGNC.

SPDYE1
Synonyms Ringo1, SPDYE, WBSCR19
Gene descriptioni

Full gene name according to HGNC.

Speedy/RINGO cell cycle regulator family member E1
Protein classi

Assigned HPA protein class(es) for the encoded protein(s).

Disease related genes
Human disease related genes
Predicted locationi

All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions.

  • Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached.

  • Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s).

The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location.

Intracellular
Protein evidence Evidence at protein level (all genes)
GENE INFORMATIONi

Gene information from Ensembl and Entrez, as well as links to available gene identifiers are displayed here. Information was retrieved from Ensembl if not indicated otherwise.

Chromosome 7
Cytoband p13
Chromosome location (bp) 43997897 - 44010124
Number of transcriptsi

Number of protein-coding transcripts from the gene as defined by Ensembl.

3
Ensembl ENSG00000136206 (version 109)
Entrez gene 285955
HGNC HGNC:16408
UniProt Q8NFV5 (UniProt - Evidence at transcript level)
neXtProt NX_Q8NFV5
GeneCards SPDYE1
Antibodypedia SPDYE1 antibodies


PROTEIN FUNCTION
Gene summary (Entrez)i

Useful information about the gene from Entrez

This gene is located at chromosome 7p13 which is close to the Williams Beuren syndrome chromosome region 7q11.23. [provided by RefSeq, Jul 2008]... show less
PROTEIN INFORMATIONi

The protein information section displays alternative protein-coding transcripts (splice variants) encoded by this gene according to the Ensembl database.

The ENSP identifier links to the Ensembl website protein summary, while the ENST identifier links to the Ensembl website transcript summary for the selected splice variant. The data in the UniProt column can be expanded to show links to all matching UniProt identifiers for this protein.

The protein classes assigned to this protein are shown if expanding the data in the protein class column. Parent protein classes are in bold font and subclasses are listed under the parent class.

The Gene Ontology terms assigned to this protein are listed if expanding the Gene ontology column. The length of the protein (amino acid residues according to Ensembl), molecular mass (kDalton), predicted signal peptide (according to a majority of the signal peptide predictors SPOCTOPUS, SignalP 4.0, and Phobius) and the number of predicted transmembrane region(s) (according to MDM) are also reported.
Splice variant SwissProt TrEMBL Protein class Gene ontology Length & mass Signal peptide
(predicted)
Transmembrane regions
(predicted)
SPDYE1-201
ENSP00000258704
ENST00000258704
Q8NFV5
[Direct mapping] Speedy protein E1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Disease related genes
Human disease related genes
   Other congenital disorders
   Chromosomal abnormalities
Mapped to neXtProt
   neXtProt - Evidence at transcript level
Show all
GO:0019901 [protein kinase binding]
GO:0045737 [positive regulation of cyclin-dependent protein serine/threonine kinase activity]
Show all
336 aa
40.7 kDa
No 0
SPDYE1-202
ENSP00000499187
ENST00000652520
A0A494C1S0
[Direct mapping] Speedy protein E1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Human disease related genes
   Other congenital disorders
   Chromosomal abnormalities
Show all
GO:0019901 [protein kinase binding]
GO:0045737 [positive regulation of cyclin-dependent protein serine/threonine kinase activity]
Show all
376 aa
45.1 kDa
No 0
SPDYE1-203
ENSP00000509569
ENST00000693451
A0A494C1S0
[Direct mapping] Speedy protein E1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Human disease related genes
   Other congenital disorders
   Chromosomal abnormalities
Show all
GO:0019901 [protein kinase binding]
GO:0045737 [positive regulation of cyclin-dependent protein serine/threonine kinase activity]
Show all
376 aa
45.1 kDa
No 0

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