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SLC22A23
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                                  • SLC22A23
                                  BRAIN PONS AND MEDULLA Show tissue menu
                                  AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
                                  MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
                                  ANTIBODIES
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                                  Brain proteome
                                  PONS AND MEDULLA - Expression summary
                                  Protein expressioni

                                  On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

                                  Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

                                  If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

                                  No data
                                  RNA expressioni

                                  A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

                                  The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

                                  Scroll down to view mRNA expression data in more detail.
                                  HPA Brain:81.8 nTPM
                                  FANTOM5:27.4 Scaled Tags Per Million
                                  Pig:29.3 nTPM
                                  Mouse:18.1 nTPM
                                  Allen mouse:1.5 Expression energy

                                  PONS AND MEDULLA - HPA Brain RNA-seq
                                  Max nTPM 81.8
                                  Sample id Sample description nTPM
                                  Anterior cochlear nucleus, ventral
                                  nTPM: 71.9
                                  2188 Female, age 91, both hemispheres 85.4
                                  2090 Male, age 80, both hemispheres 76.1
                                  2301 Female, age 85, both hemispheres 72.1
                                  1984 Male, age 76, both hemispheres 54.0
                                  Area postrema
                                  nTPM: 75.3
                                  2306 Male, age 80, both hemispheres 80.5
                                  2799 Male, age 61, both hemispheres 77.7
                                  2054 Male, age 76, both hemispheres 67.7
                                  Dorsal cochlear nucleus
                                  nTPM: 70.8
                                  2802 Male, age 74, right hemisphere 75.5
                                  2378 Male, age 80, both hemispheres 73.1
                                  2187 Female, age 91, both hemispheres 69.2
                                  2370 Male, age 61, both hemispheres 68.8
                                  2058 Male, age 76, both hemispheres 67.3
                                  Dorsal medullary reticular nucleus
                                  nTPM: 80.5
                                  2088 Male, age 76, both hemispheres 86.9
                                  2373 Male, age 61, both hemispheres 79.8
                                  2040 Female, age 85, both hemispheres 74.8
                                  Dorsal motor vagal complex
                                  nTPM: 61.0
                                  2185 Male, age 76, both hemispheres 96.1
                                  2643 Male, age 74, both hemispheres 73.3
                                  2000 Male, age 74, unknown 60.9
                                  2133 Female, age 91, both hemispheres 57.4
                                  2797 Male, age 61, both hemispheres 56.2
                                  2844 Male, age 55, unknown 48.6
                                  2813 Female, age 72, unknown 48.0
                                  2807 Female, age 85, both hemispheres 47.7
                                  Dorsal tegmental nucleus
                                  nTPM: 64.3
                                  2083 Male, age 80, both hemispheres 82.0
                                  2358 Male, age 61, both hemispheres 59.9
                                  2326 Male, age 74, both hemispheres 57.8
                                  1936 Male, age 76, left hemisphere 57.4
                                  Dorsolateral tegmental area
                                  nTPM: 72.2
                                  2337 Male, age 61, both hemispheres 95.7
                                  2751 Female, age 85, both hemispheres 82.4
                                  2654 Male, age 80, both hemispheres 80.5
                                  2141 Male, age 76, both hemispheres 53.2
                                  2360 Male, age 74, both hemispheres 49.2
                                  Gigantocellular reticular nuclei, medullary
                                  nTPM: 72.0
                                  2387 Female, age 91, both hemispheres 77.3
                                  2022 Male, age 76, right hemisphere 75.7
                                  1876 Female, age 85, both hemispheres 73.6
                                  2310 Male, age 80, both hemispheres 69.0
                                  2462 Male, age 74, both hemispheres 68.9
                                  2314 Male, age 61, both hemispheres 67.7
                                  Gigantocellular reticular nuclei, pars
                                  nTPM: 74.0
                                  2706 Male, age 80, both hemispheres 80.2
                                  2330 Male, age 80, both hemispheres 75.4
                                  2336 Male, age 61, both hemispheres 75.0
                                  2084 Female, age 85, both hemispheres 74.6
                                  2168 Male, age 76, both hemispheres 64.5
                                  Inferior olive
                                  nTPM: 63.9
                                  2178 Male, age 61, both hemispheres 74.2
                                  2628 Female, age 91, both hemispheres 69.3
                                  2563 Male, age 74, both hemispheres 62.8
                                  2379 Male, age 80, both hemispheres 59.6
                                  2085 Female, age 85, both hemispheres 53.6
                                  Kolliker-Fuse nucleus
                                  nTPM: 68.9
                                  2793 Female, age 91, left hemisphere 93.4
                                  2163 Male, age 80, both hemispheres 63.6
                                  2315 Male, age 76, right hemisphere 49.6
                                  Lateral lemniscal nuclei
                                  nTPM: 79.4
                                  2320 Female, age 91, left hemisphere 90.5
                                  2036 Male, age 80, both hemispheres 85.2
                                  2746 Female, age 85, left hemisphere 81.0
                                  2453 Male, age 74, right hemisphere 75.0
                                  2169 Male, age 76, both hemispheres 65.1
                                  Lateral medullary reticular nucleus
                                  nTPM: 69.9
                                  2852 Male, age 80, both hemispheres 89.4
                                  2044 Male, age 76, both hemispheres 75.6
                                  2305 Male, age 74, both hemispheres 71.1
                                  2374 Male, age 61, both hemispheres 69.8
                                  2190 Female, age 85, both hemispheres 57.1
                                  2804 Female, age 91, both hemispheres 56.2
                                  Lateral parabrachial nucleus
                                  nTPM: 77.6
                                  2790 Male, age 61, both hemispheres 93.2
                                  2013 Male, age 80, both hemispheres 76.6
                                  2792 Male, age 76, both hemispheres 74.8
                                  2139 Female, age 85, right hemisphere 65.8
                                  Lateral vestibular nucleus
                                  nTPM: 68.4
                                  2184 Male, age 76, both hemispheres 72.9
                                  2311 Male, age 80, both hemispheres 63.9
                                  Locus coeruleus
                                  nTPM: 45.5
                                  2162 Male, age 80, both hemispheres 56.3
                                  2317 Female, age 72, unknown 48.2
                                  2720 Male, age 74, both hemispheres 47.7
                                  2123 Female, age 91, both hemispheres 45.0
                                  2014 Male, age 55, unknown 44.5
                                  1980 Male, age 76, both hemispheres 43.6
                                  2788 Male, age 74, unknown 33.3
                                  Medial olivary nucleus
                                  nTPM: 73.2
                                  1943 Male, age 61, both hemispheres 95.3
                                  1962 Male, age 76, both hemispheres 68.4
                                  2851 Male, age 80, both hemispheres 66.3
                                  2138 Female, age 91, both hemispheres 62.6
                                  Medial parabrachial nucleus
                                  nTPM: 75.5
                                  2156 Male, age 61, both hemispheres 84.9
                                  2463 Female, age 85, right hemisphere 82.8
                                  2786 Male, age 76, both hemispheres 73.3
                                  2170 Female, age 91, both hemispheres 73.1
                                  2854 Male, age 80, both hemispheres 63.4
                                  Medial periolivary nuclei
                                  nTPM: 73.9
                                  2081 Male, age 80, both hemispheres 87.2
                                  2458 Female, age 91, both hemispheres 81.8
                                  2171 Female, age 85, both hemispheres 72.7
                                  2791 Male, age 74, right hemisphere 71.5
                                  2063 Male, age 76, both hemispheres 56.3
                                  Medial vestibular nucleus
                                  nTPM: 66.6
                                  2093 Male, age 80, both hemispheres 85.1
                                  2803 Female, age 91, both hemispheres 72.6
                                  2624 Male, age 61, both hemispheres 68.8
                                  2801 Male, age 74, both hemispheres 66.2
                                  2743 Female, age 85, both hemispheres 58.6
                                  2134 Male, age 76, both hemispheres 48.3
                                  Motor facial nucleus
                                  nTPM: 72.0
                                  2126 Male, age 61, both hemispheres 87.5
                                  2697 Female, age 85, both hemispheres 74.3
                                  2327 Male, age 80, both hemispheres 72.9
                                  2365 Male, age 74, right hemisphere 69.9
                                  2795 Female, age 91, both hemispheres 67.5
                                  2062 Male, age 76, both hemispheres 60.2
                                  Motor hypoglossal nucleus
                                  nTPM: 66.2
                                  2125 Female, age 91, both hemispheres 79.5
                                  2182 Male, age 80, both hemispheres 73.8
                                  2132 Female, age 85, both hemispheres 71.0
                                  2277 Male, age 76, both hemispheres 63.2
                                  2461 Male, age 61, both hemispheres 43.4
                                  Motor trigeminal nucleus
                                  nTPM: 80.6
                                  2560 Male, age 74, both hemispheres 89.9
                                  2321 Female, age 91, both hemispheres 85.3
                                  2309 Male, age 76, both hemispheres 82.5
                                  2079 Male, age 80, both hemispheres 78.0
                                  2335 Male, age 61, both hemispheres 67.0
                                  Nuclei of the trapezoid body
                                  nTPM: 71.8
                                  2166 Male, age 80, both hemispheres 81.7
                                  2159 Male, age 61, both hemispheres 76.2
                                  2368 Female, age 91, both hemispheres 75.9
                                  2735 Female, age 85, both hemispheres 70.0
                                  1983 Male, age 76, both hemispheres 55.4
                                  Nucleus ambiguus
                                  nTPM: 79.5
                                  2096 Female, age 85, both hemispheres 91.6
                                  2071 Male, age 76, both hemispheres 67.4
                                  Nucleus cuneatus
                                  nTPM: 79.5
                                  2100 Male, age 76, both hemispheres 97.1
                                  2131 Male, age 76, both hemispheres 85.1
                                  2376 Male, age 61, both hemispheres 83.2
                                  2380 Male, age 80, both hemispheres 82.9
                                  2564 Male, age 74, both hemispheres 81.5
                                  2805 Female, age 91, both hemispheres 80.9
                                  2562 Male, age 61, both hemispheres 69.6
                                  2381 Male, age 80, both hemispheres 68.6
                                  2808 Female, age 85, both hemispheres 66.3
                                  Nucleus gracilis
                                  nTPM: 79.9
                                  2382 Male, age 80, both hemispheres 93.8
                                  2627 Male, age 74, both hemispheres 78.2
                                  2299 Female, age 85, both hemispheres 67.6
                                  Nucleus raphe magnus
                                  nTPM: 71.3
                                  2459 Female, age 91, both hemispheres 84.5
                                  2328 Male, age 80, both hemispheres 78.1
                                  2051 Male, age 76, both hemispheres 72.2
                                  2172 Female, age 85, both hemispheres 68.6
                                  2455 Male, age 74, both hemispheres 64.1
                                  2160 Male, age 61, both hemispheres 60.1
                                  Nucleus raphe obscurus
                                  nTPM: 80.6
                                  2142 Male, age 76, midline 86.7
                                  2800 Male, age 61, midline 83.3
                                  2845 Female, age 85, midline 71.8
                                  Nucleus raphe pallidus
                                  nTPM: 77.9
                                  1924 Male, age 61, midline 96.1
                                  2145 Male, age 76, midline 75.0
                                  2183 Male, age 80, midline 62.5
                                  Nucleus tractus solitarii
                                  nTPM: 42.6
                                  2656 Male, age 76, both hemispheres 60.4
                                  2307 Male, age 80, both hemispheres 45.2
                                  2191 Female, age 85, both hemispheres 32.7
                                  2144 Female, age 91, right hemisphere 32.0
                                  Paramedian reticular nucleus
                                  nTPM: 69.0
                                  2057 Male, age 80, both hemispheres 76.5
                                  2050 Female, age 85, both hemispheres 72.9
                                  2052 Male, age 76, both hemispheres 65.6
                                  2313 Male, age 61, both hemispheres 60.8
                                  Parvicellular reticular nuclei
                                  nTPM: 80.3
                                  2558 Male, age 74, both hemispheres 90.5
                                  2119 Male, age 80, both hemispheres 77.5
                                  2095 Male, age 76, both hemispheres 72.9
                                  Parvicellular reticular nuclei, medullary
                                  nTPM: 62.7
                                  2189 Female, age 91, both hemispheres 66.9
                                  2091 Female, age 85, both hemispheres 65.2
                                  2181 Male, age 80, left hemisphere 56.1
                                  Pedunculopontine tegmental nucleus
                                  nTPM: 64.7
                                  2338 Male, age 61, both hemispheres 78.6
                                  2334 Male, age 80, both hemispheres 59.0
                                  1921 Female, age 85, both hemispheres 56.4
                                  Peritrigeminal nucleus
                                  nTPM: 69.0
                                  2179 Male, age 61, both hemispheres 74.6
                                  2067 Female, age 85, both hemispheres 66.7
                                  2136 Male, age 76, both hemispheres 65.7
                                  Pontine nuclei
                                  nTPM: 81.8
                                  2115 Male, age 80, left hemisphere 93.4
                                  2454 Male, age 74, left hemisphere 87.8
                                  2787 Female, age 85, both hemispheres 83.9
                                  1863 Male, age 55, unknown 81.5
                                  2109 Female, age 72, unknown 79.9
                                  2319 Female, age 91, both hemispheres 79.7
                                  1968 Male, age 76, left hemisphere 79.1
                                  2727 Male, age 61, right hemisphere 69.0
                                  Pontine raphe nucleus
                                  nTPM: 60.9
                                  2122 Female, age 85, midline 65.0
                                  2853 Male, age 76, midline 56.8
                                  Posteroventral cochlear nucleus
                                  nTPM: 77.1
                                  2135 Female, age 91, both hemispheres 95.9
                                  2070 Male, age 76, both hemispheres 83.0
                                  2341 Male, age 80, both hemispheres 74.6
                                  2371 Male, age 61, both hemispheres 68.7
                                  2752 Female, age 85, both hemispheres 63.1
                                  Prepositus hypoglossal nucleus
                                  nTPM: 60.4
                                  2855 Female, age 85, right hemisphere 64.6
                                  2086 Male, age 80, both hemispheres 56.2
                                  Principal sensory trigeminal nucleus
                                  nTPM: 69.7
                                  2367 Female, age 91, left hemisphere 78.7
                                  2008 Male, age 80, left hemisphere 70.8
                                  2158 Male, age 61, both hemispheres 67.5
                                  2324 Male, age 76, both hemispheres 62.0
                                  Reticular pontine nucleus, caudal
                                  nTPM: 80.6
                                  2559 Male, age 74, both hemispheres 93.1
                                  2332 Male, age 80, right hemisphere 82.6
                                  2457 Female, age 91, both hemispheres 76.0
                                  2092 Male, age 76, both hemispheres 70.6
                                  Reticular pontine nucleus, oral
                                  nTPM: 77.7
                                  2366 Female, age 91, both hemispheres 85.5
                                  1939 Male, age 80, both hemispheres 82.2
                                  2167 Male, age 76, both hemispheres 77.0
                                  2012 Female, age 85, both hemispheres 73.6
                                  2361 Male, age 74, both hemispheres 70.1
                                  Reticulotegmental nucleus
                                  nTPM: 72.9
                                  2333 Male, age 80, both hemispheres 78.7
                                  2452 Male, age 74, both hemispheres 77.7
                                  2322 Female, age 91, both hemispheres 72.4
                                  2325 Male, age 76, both hemispheres 62.8
                                  Spinal trigeminal nucleus, caudal
                                  nTPM: 70.9
                                  2447 Male, age 76, both hemispheres 78.7
                                  2312 Male, age 61, both hemispheres 75.4
                                  2308 Male, age 80, both hemispheres 71.5
                                  2642 Male, age 74, both hemispheres 69.3
                                  2390 Female, age 91, both hemispheres 59.8
                                  Spinal trigeminal nucleus, interpolar
                                  nTPM: 59.0
                                  2033 Male, age 80, both hemispheres 66.3
                                  2066 Male, age 76, right hemisphere 64.3
                                  2389 Female, age 91, both hemispheres 60.5
                                  2386 Female, age 85, both hemispheres 58.7
                                  2625 Male, age 61, both hemispheres 45.4
                                  Spinal trigeminal nucleus, oral
                                  nTPM: 64.8
                                  2164 Male, age 80, both hemispheres 71.5
                                  1978 Male, age 76, both hemispheres 66.1
                                  2737 Female, age 85, both hemispheres 56.7
                                  Spinal vestibular nucleus
                                  nTPM: 75.3
                                  2748 Male, age 76, both hemispheres 91.2
                                  2384 Male, age 74, both hemispheres 86.0
                                  2186 Female, age 91, both hemispheres 76.4
                                  2780 Male, age 80, both hemispheres 75.6
                                  2806 Female, age 85, both hemispheres 66.9
                                  2796 Male, age 61, both hemispheres 55.5
                                  Subcoeruleus area
                                  nTPM: 67.9
                                  2369 Female, age 85, left hemisphere 85.2
                                  2089 Male, age 76, left hemisphere 74.2
                                  2451 Male, age 74, both hemispheres 65.5
                                  1958 Male, age 80, both hemispheres 61.7
                                  2323 Female, age 91, left hemisphere 53.1
                                  Superior olive
                                  nTPM: 76.8
                                  2329 Male, age 80, right hemisphere 83.6
                                  2561 Female, age 91, both hemispheres 81.3
                                  2020 Male, age 76, both hemispheres 75.6
                                  1875 Female, age 85, both hemispheres 74.1
                                  2364 Male, age 74, right hemisphere 69.6
                                  Superior vestibular nucleus
                                  nTPM: 55.4
                                  2015 Male, age 80, both hemispheres 62.9
                                  2061 Male, age 76, both hemispheres 62.7
                                  2383 Male, age 74, both hemispheres 40.7
                                  Ventral medullary reticular nucleus
                                  nTPM: 81.2
                                  2060 Male, age 76, both hemispheres 91.6
                                  2372 Male, age 61, both hemispheres 70.9
                                  Ventral periolivary nuclei
                                  nTPM: 71.5
                                  2023 Male, age 76, both hemispheres 79.0
                                  2794 Female, age 91, left hemisphere 71.8
                                  2165 Male, age 80, both hemispheres 69.7
                                  2130 Female, age 85, both hemispheres 65.6
                                  Ventrolateral medulla, A1-C1 cell groups
                                  nTPM: 67.9
                                  2118 Male, age 80, both hemispheres 75.2
                                  1986 Male, age 76, both hemispheres 74.0
                                  2741 Female, age 85, both hemispheres 66.8
                                  2180 Male, age 61, both hemispheres 65.0
                                  2302 Female, age 91, both hemispheres 58.7
                                  Ventrolateral tegmental area, A5 NE cell group
                                  nTPM: 74.5
                                  2456 Female, age 91, both hemispheres 88.1
                                  2359 Male, age 61, both hemispheres 75.8
                                  2449 Male, age 74, both hemispheres 75.3
                                  2161 Male, age 80, both hemispheres 74.1
                                  2840 Female, age 85, both hemispheres 70.4
                                  1959 Male, age 76, both hemispheres 63.6

                                  PONS AND MEDULLA - FANTOM5 CAGEi

                                  RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

                                  Max Scaled Tags Per Million 27.4
                                  FANTOM5 sample id Sample description Scaled Tags Per Million
                                  Locus coeruleus
                                  Scaled Tags Per Million: 23.5
                                  FF:10165-103B3 76 years, female 26.9
                                  FF:10182-103D2 60 years, female 20.2
                                  Medulla oblongata
                                  Scaled Tags Per Million: 21.4
                                  FF:10038-101F2 18-64 years, mixed 28.4
                                  FF:10155-103A2 76 years, female 22.1
                                  FF:10174-103C3 60 years, female 13.6
                                  Pons
                                  Scaled Tags Per Million: 27.4
                                  FF:10033-101E6 18-54 years, mixed 27.4

                                  PONS AND MEDULLA - Pig RNA-seqi

                                  RNA-seq data obtained from pig brain is reported as nTPM .

                                  Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
                                  Average nTPM 29.3
                                  Pig sample Sample description nTPM
                                  27.329.531.624.533.9051015202530
                                  27.329.531.624.533.9051015202530
                                  Medulla oblongata
                                  nTPM: 29.4
                                  Samples: 4

                                  Max nTPM: 33.9
                                  Min nTPM: 24.5
                                  Sample A Female 33.9
                                  Sample B Female 28.2
                                  Sample C Male 30.8
                                  Sample D Male 24.5
                                  20.423.626.818.429.30246810121416182022242628
                                  20.423.626.818.429.30246810121416182022242628
                                  Pons
                                  nTPM: 23.7
                                  Samples: 4

                                  Max nTPM: 29.3
                                  Min nTPM: 18.4
                                  Sample A Female 29.3
                                  Sample B Female 21.1
                                  Sample C Male 18.4
                                  Sample D Male 26.0

                                  PONS AND MEDULLA - Mouse RNA-seqi

                                  RNA-seq data obtained from mouse brain is reported as nTPM .

                                  Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
                                  Average nTPM 18.1
                                  Mouse sample Sample description nTPM
                                  17.418.218.917.318.9024681012141618
                                  17.418.218.917.318.9024681012141618
                                  Pons and medulla
                                  nTPM: 18.2
                                  Samples: 4

                                  Max nTPM: 18.9
                                  Min nTPM: 17.3
                                  Sample A Male 17.5
                                  Sample B Male 18.9
                                  Sample C Female 17.3
                                  Sample D Female 18.9

                                  PONS AND MEDULLA - Allen Mouse ISHi

                                  In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

                                  Max Expression energy 1.5
                                  Allen experiment id Experiment description Expression energy
                                  Medulla oblongata
                                  Expression energy: 1.5
                                  69407439 Antisense, RP_050414_01_F08, Mouse strain C57BL/6J (56 days, male) 1.6
                                  72128754 Antisense, RP_051017_04_C10, Mouse strain C57BL/6J (56 days, male) 1.3
                                  Pons
                                  Expression energy: 1.5
                                  69407439 Antisense, RP_050414_01_F08, Mouse strain C57BL/6J (56 days, male) 1.5
                                  72128754 Antisense, RP_051017_04_C10, Mouse strain C57BL/6J (56 days, male) 1.5

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                                  The Human Protein Atlas project is funded
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