Expression of RPL11 in testis cancer - The Human Protein Atlas

TESTIS CANCER - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

RPL11 is not prognostic in testis cancer

Stage:

Survival analysis

Current cut offⁱ :

Best expression cut offⁱ : 582.86

Median expressionⁱ : N/A

Median follow up timeⁱ : N/A

P scoreⁱ N/A

5-year survival highⁱ N/A

5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

740.7

Number of samples

134

Samples

Sample	Description	FPKM
TCGA-2G-AAHL-01A	26 years, male, white, stage:i, alive, 7081 days	1799.1
TCGA-2G-AAFM-01A	31 years, male, white, stage:iia, alive, 503 days	1458.4
TCGA-2G-AAGF-01A	28 years, male, white, stage:is, alive, 2734 days	1427.8
TCGA-2G-AAFN-01A	26 years, male, white, stage:iiib, alive, 773 days	1386.6
TCGA-2G-AAKG-01A	22 years, male, white, stage:i, alive, 6598 days	1382.5
TCGA-ZM-AA06-01A	45 years, male, white, stage:ib, alive, 1498 days	1303.6
TCGA-2G-AAKD-01A	18 years, male, white, stage:iii, alive, 6340 days	1287.8
TCGA-2G-AAFO-01A	33 years, male, white, stage:iia, alive, 685 days	1171.4
TCGA-2G-AAGZ-01A	27 years, male, white, stage:iiia, alive, 5233 days	1169.1
TCGA-2G-AAGJ-01A	28 years, male, black or african american, stage:ia, alive, 2938 days	1148.3
TCGA-XE-AAOD-01A	39 years, male, white, stage:ib, alive, 2058 days	1130.6
TCGA-VF-A8AC-01A	29 years, male, white, stage:ia, alive, 1083 days	1070.7
TCGA-2G-AAHP-01A	31 years, male, white, stage:is, alive, 5667 days	1045.7
TCGA-VF-A8A8-01A	18 years, male, white, stage:ia, alive, 1131 days	1033.4
TCGA-ZM-AA0E-01A	39 years, male, white, stage:ia, alive, 811 days	1022.8
TCGA-2G-AAFL-01A	35 years, male, white, stage:ib, alive, 750 days	979.5
TCGA-2G-AAGA-01A	38 years, male, white, stage:iia, alive, 2439 days	970.0
TCGA-XE-AANR-01A	24 years, male, white, stage:i, alive, 14 days	966.8
TCGA-2G-AAGK-01A	20 years, male, white, stage:is, alive, 3621 days	962.2
TCGA-ZM-AA0B-01A	32 years, male, white, stage:ia, alive, 838 days	941.9
TCGA-2G-AALP-01A	43 years, male, white, stage:iiib, alive, 2645 days	937.1
TCGA-VF-A8AE-01A	39 years, male, white, stage:ia, alive, 727 days	924.2
TCGA-XE-AAOF-01A	50 years, male, asian, stage:ia, alive, 1268 days	912.2
TCGA-XE-AAO6-01A	47 years, male, white, stage:ia, alive, 240 days	908.8
TCGA-XE-AAOJ-01A	24 years, male, white, stage:is, alive, 1550 days	908.8
TCGA-SO-A8JP-01A	29 years, male, white, stage:i, alive, 540 days	906.5
TCGA-SB-A6J6-01A	22 years, male, white, stage:ia, alive, 413 days	905.6
TCGA-WZ-A8D5-01A	38 years, male, white, alive, 774 days	899.0
TCGA-2G-AAGE-01A	21 years, male, white, stage:is, alive, 2478 days	890.3
TCGA-SN-A84Y-01A	18 years, male, white, stage:is, alive, 524 days	886.5
TCGA-2G-AAEX-01A	38 years, male, white, stage:is, alive, 1259 days	882.6
TCGA-VF-A8AA-01A	51 years, male, white, stage:i, alive, 1146 days	878.3
TCGA-ZM-AA0D-01A	34 years, male, white, stage:ia, alive, 848 days	878.3
TCGA-2G-AAHG-01A	25 years, male, white, stage:i, alive, 1819 days	873.7
TCGA-S6-A8JX-01A	27 years, male, white, stage:ib, alive, 552 days	872.8
TCGA-2G-AAGO-01A	41 years, male, white, stage:is, alive, 4026 days	871.0
TCGA-2G-AAHN-01A	32 years, male, white, stage:i, alive, 6445 days	870.2
TCGA-YU-A90W-01A	45 years, male, white, stage:ia, alive, 1113 days	865.9
TCGA-2G-AAL7-01A	32 years, male, white, stage:is, alive, 3991 days	862.8
TCGA-SN-A84X-01A	21 years, male, white, stage:is, alive, 312 days	861.0
TCGA-XE-A8H4-01A	23 years, male, white, stage:ia, alive, 559 days	858.7
TCGA-4K-AAAL-01A	31 years, male, white, stage:is, alive, 483 days	856.2
TCGA-2G-AAG9-01A	25 years, male, white, stage:iiib, alive, 2234 days	855.3
TCGA-VF-A8AD-01A	36 years, male, white, stage:ib, alive, 1006 days	853.4
TCGA-WZ-A7V3-01A	20 years, male, white, stage:i, alive, 753 days	836.8
TCGA-XE-AAO4-01A	40 years, male, white, stage:ia, alive, 367 days	831.1
TCGA-2G-AAFI-01A	41 years, male, white, stage:ib, alive, 675 days	816.4
TCGA-2G-AAKM-01A	14 years, male, white, stage:ii, dead, 6972 days	811.8
TCGA-2G-AAG0-01A	23 years, male, white, stage:is, alive, 1529 days	810.3
TCGA-2G-AAG8-01A	21 years, male, white, stage:ib, alive, 2289 days	806.2
TCGA-XE-AAO3-01A	33 years, male, asian, stage:i, alive, 2857 days	804.7
TCGA-W4-A7U4-01A	23 years, male, white, alive, 738 days	802.7
TCGA-2G-AAFH-01A	38 years, male, white, stage:iib, alive, 1375 days	801.1
TCGA-2G-AAKH-01A	19 years, male, white, stage:ii, alive, 6862 days	800.1
TCGA-2G-AAF8-01A	33 years, male, white, stage:ia, alive, 3911 days	798.7
TCGA-VF-A8A9-01A	31 years, male, white, stage:ia, alive, 1119 days	793.2
TCGA-4K-AA1I-01A	26 years, male, white, stage:ia, alive, 3 days	786.6
TCGA-2G-AAF6-01A	28 years, male, white, stage:is, alive, 3491 days	784.8
TCGA-S6-A8JY-01A	27 years, male, white, stage:is, alive, 278 days	781.0
TCGA-2G-AAGW-01A	38 years, male, white, stage:is, alive, 4899 days	778.8
TCGA-2G-AAH8-01A	45 years, male, white, stage:iiic, alive, 2248 days	773.6
TCGA-2G-AAGN-01A	41 years, male, white, stage:iiib, alive, 3656 days	746.8
TCGA-2G-AAFG-01A	30 years, male, white, stage:is, alive, 6183 days	738.8
TCGA-2G-AAKL-01A	26 years, male, white, stage:ii, alive, 7023 days	733.7
TCGA-YU-A90Q-01A	21 years, male, stage:ib, alive, 1964 days	729.7
TCGA-XE-AANV-01A	52 years, male, stage:ib, alive, 1701 days	729.7
TCGA-XE-A8H5-01A	29 years, male, stage:is, alive, 1217 days	722.8
TCGA-XE-A8H1-01A	24 years, male, white, stage:is, alive, 209 days	719.7
TCGA-XE-AANJ-01A	39 years, male, white, stage:is, alive, 2007 days	705.4
TCGA-XY-A8S2-01A	67 years, male, white, stage:i, alive, 672 days	696.3
TCGA-YU-A90P-01A	25 years, male, white, stage:ia, alive, 2069 days	694.1
TCGA-2G-AAGC-01A	28 years, male, white, stage:is, alive, 2585 days	691.8
TCGA-ZM-AA0H-01A	50 years, male, white, stage:is, alive, 1736 days	690.9
TCGA-XE-AAOL-01A	38 years, male, black or african american, stage:i, alive, 13 days	683.1
TCGA-YU-A94D-01A	28 years, male, stage:iiib, alive, 2167 days	682.4
TCGA-2G-AAH4-01A	34 years, male, white, stage:ii, alive, 6210 days	677.5
TCGA-SN-A6IS-01A	26 years, male, white, stage:is, alive, 496 days	674.4
TCGA-YU-A912-01A	34 years, male, black or african american, stage:iiic, alive, 866 days	662.8
TCGA-XY-A8S3-01B	24 years, male, white, stage:is, alive, 843 days	661.8
TCGA-XE-A9SE-01A	35 years, male, white, stage:ia, alive, 708 days	654.8
TCGA-X3-A8G4-01A	33 years, male, white, stage:is, alive, 856 days	653.3
TCGA-WZ-A7V5-01A	27 years, male, white, stage:i, alive, 1061 days	647.0
TCGA-4K-AA1H-01A	26 years, male, white, stage:ia, alive, 518 days	646.2
TCGA-ZM-AA0N-01A	44 years, male, white, stage:ib, alive, 634 days	645.0
TCGA-2G-AAHA-01A	48 years, male, white, stage:ib, alive, 3349 days	644.5
TCGA-2G-AAFE-01A	37 years, male, white, stage:iia, alive, 4702 days	638.7
TCGA-2G-AAF4-01A	30 years, male, white, stage:i, alive, 2315 days	637.6
TCGA-VF-A8AB-01A	31 years, male, black or african american, stage:ia, alive, 760 days	623.6
TCGA-S6-A8JW-01A	37 years, male, white, stage:is, alive, 698 days	621.3
TCGA-2G-AAH0-01A	30 years, male, white, stage:is, alive, 5477 days	620.9
TCGA-2G-AAH3-01A	20 years, male, white, stage:i, alive, 1822 days	619.9
TCGA-4K-AA1G-01A	34 years, male, white, stage:is, alive, 436 days	619.7
TCGA-2G-AAG3-01A	53 years, male, white, stage:is, alive, 1593 days	606.4
TCGA-WZ-A7V4-01A	28 years, male, white, stage:i, alive, 894 days	603.4
TCGA-YU-A90S-01A	26 years, male, white, stage:ia, alive, 971 days	602.8
TCGA-W4-A7U2-01A	26 years, male, white, alive, 1263 days	600.9
TCGA-2G-AAL5-01A	31 years, male, white, stage:i, alive, 7437 days	596.2
TCGA-ZM-AA0F-01A	35 years, male, white, stage:ia, alive, 681 days	593.5
TCGA-XY-A9T9-01A	37 years, male, white, stage:is, alive, 281 days	588.0
TCGA-XY-A89B-01A	35 years, male, white, stage:ia, alive, 471 days	583.2
TCGA-YU-A90Y-01A	23 years, male, black or african american, stage:iiic, dead, 17 days	582.5
TCGA-XE-AAOB-01A	27 years, male, white, stage:is, dead, 513 days	577.9
TCGA-SB-A76C-01A	38 years, male, white, alive, 42 days	577.3
TCGA-2G-AAGG-01A	20 years, male, white, stage:iiic, alive, 2611 days	570.9
TCGA-2G-AAF1-01A	28 years, male, asian, stage:is, alive, 1403 days	570.5
TCGA-YU-AA4L-01A	27 years, male, black or african american, stage:iiic, alive, 1573 days	548.5
TCGA-2G-AAHT-01A	32 years, male, white, stage:is, alive, 542 days	546.2
TCGA-2G-AAGM-01A	51 years, male, white, stage:is, alive, 3891 days	540.0
TCGA-2G-AAEW-01A	31 years, male, white, stage:is, dead, 618 days	522.9
TCGA-2G-AAHC-01A	33 years, male, white, stage:is, alive, 5539 days	512.1
TCGA-2G-AAGS-01A	39 years, male, white, stage:iiib, alive, 4816 days	480.2
TCGA-2G-AAFJ-01A	23 years, male, asian, alive, 792 days	477.8
TCGA-YU-AA61-01A	29 years, male, white, stage:is, alive, 864 days	470.5
TCGA-2G-AAFZ-01A	32 years, male, white, stage:iii, alive, 1353 days	469.1
TCGA-ZM-AA05-01A	36 years, male, white, stage:iic, alive, 1126 days	462.7
TCGA-2G-AAFY-01A	24 years, male, white, stage:iia, alive, 1099 days	462.3
TCGA-2G-AAG7-01A	33 years, male, white, stage:is, alive, 2475 days	442.0
TCGA-2G-AAGI-01A	33 years, male, white, stage:is, alive, 3137 days	439.6
TCGA-2G-AAGT-01A	30 years, male, white, stage:is, alive, 4406 days	432.0
TCGA-W4-A7U3-01A	26 years, male, white, alive, 149 days	429.6
TCGA-2X-A9D5-01A	49 years, male, white, stage:i, alive, 435 days	427.9
TCGA-2G-AAGX-01A	22 years, male, white, stage:ia, alive, 5514 days	426.8
TCGA-2G-AAGV-01A	23 years, male, white, alive, 4527 days	424.9
TCGA-2X-A9D6-01A	42 years, male, white, stage:i, alive, 607 days	421.4
TCGA-XE-AAOC-01A	31 years, male, white, stage:ia, alive, 270 days	398.2
TCGA-2G-AAFV-01A	31 years, male, white, stage:is, alive, 1389 days	398.2
TCGA-2G-AAGY-01A	28 years, male, white, stage:is, alive, 5329 days	341.1
TCGA-2G-AAH2-01A	20 years, male, white, stage:is, alive, 6060 days	335.9
TCGA-YU-A94I-01A	66 years, male, stage:ia, alive, 536 days	329.5
TCGA-2G-AAG5-01A	36 years, male, white, stage:is, alive, 2299 days	327.5
TCGA-SN-A84W-01A	30 years, male, white, stage:is, alive, 293 days	310.6
TCGA-2G-AAG6-01A	24 years, male, white, stage:is, alive, 2231 days	304.7
TCGA-2G-AAGP-01A	33 years, male, white, stage:iia, alive, 4018 days	288.2
TCGA-XE-AANI-01A	37 years, male, white, stage:is, alive, 1041 days	227.1
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TESTIS CANCER - Protein expressionⁱ A mouse-over function shows sample information and annotation data. Click on an image to view it in a full screen mode. Samples can be filtered based on level of antibody staining by selecting one or several of the following categories: high, medium, low and not detected. The assay and annotation is described here. Note that samples used for immunohistochemistry by the Human Protein Atlas do not correspond to samples in the TCGA dataset.

Antibody stainingⁱ Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells. Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.	Antibody HPA002734
Staining
High
Medium
Low
Not detected
Intensity
Strong
Moderate
Weak
Negative
Quantity
>75%
75%-25%
<25%
None
Location
Nuclear
Cytoplasmic/membranous
Cytoplasmic/membranous,nuclear
None
Click images for details