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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
No data
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
11.2
nTPM
HPA Brain:
25.9
nTPM
GTEx:
11.2
nTPM
MIDBRAIN - Annotated protein expression
Pending normal tissue analysis
MIDBRAIN - HPA Brain RNA-seq
Max nTPM
25.9
Sample id
Sample description
nTPM
Cuneiform nucleus nTPM: 24.1
2586
Male, age 75, left hemisphere
30.8
2828
Female, age 72, unknown
25.5
1833
Male, age 53, unknown
24.9
2666
Male, age 74, left hemisphere
24.7
1830
Male, age 51, unknown
23.8
2019
Male, age 18, unknown
23.1
1827
Male, age 72, unknown
22.7
2219
Male, age 76, both hemispheres
22.6
1870
Female, age 42, unknown
21.7
2411
Female, age 72, unknown
21.5
Dorsal raphe nucleus nTPM: 21.1
2750
Male, age 76, both hemispheres
23.0
2047
Male, age 72, unknown
21.8
2016
Female, age 72, unknown
21.7
1828
Male, age 53, unknown
19.7
2298
Female, age 72, unknown
19.0
Inferior colliculus nTPM: 23.4
1890
Male, age 53, unknown
24.9
2849
Male, age 72, unknown
24.2
1848
Female, age 42, unknown
22.6
2097
Female, age 72, unknown
21.9
Median raphe nucleus nTPM: 24.4
2220
Male, age 76, midline
24.4
Periaquaductal grey, anterior nTPM: 22.6
1947
Male, age 18, unknown
23.7
2502
Female, age 75, unknown
23.6
1795
Male, age 51, unknown
20.7
Periaquaductal grey, dorsal nTPM: 21.4
2464
Female, age 72, unknown
22.2
2850
Male, age 76, both hemispheres
21.5
1831
Male, age 72, unknown
21.1
1840
Male, age 53, unknown
20.9
Periaquaductal grey, lateral nTPM: 19.3
2053
Male, age 18, unknown
21.4
2140
Male, age 76, both hemispheres
19.0
2272
Male, age 74, both hemispheres
17.4
Pretectal area nTPM: 21.3
2407
Male, age 75, both hemispheres
27.4
2007
Male, age 72, unknown
23.7
1816
Male, age 51, unknown
23.2
2316
Male, age 76, right hemisphere
23.0
1944
Female, age 72, unknown
22.9
2825
Male, age 18, unknown
21.9
2224
Female, age 72, unknown
21.3
1815
Male, age 53, unknown
20.5
1817
Female, age 42, unknown
19.6
2273
Male, age 74, both hemispheres
16.2
2667
Female, age 75, unknown
14.7
Red nucleus nTPM: 25.9
2584
Male, age 75, left hemisphere
32.4
2725
Female, age 75, unknown
32.2
2588
Male, age 74, left hemisphere
29.1
2823
Male, age 76, right hemisphere
27.7
1865
Male, age 51, unknown
26.6
1904
Male, age 53, unknown
25.4
2769
Male, age 72, unknown
24.9
2785
Male, age 18, unknown
23.6
2503
Female, age 72, unknown
23.5
2227
Male, age 72, unknown
22.7
1954
Female, age 42, unknown
22.2
1821
Female, age 72, unknown
20.1
Substantia nigra nTPM: 22.7
2583
Male, age 75, right hemisphere
28.3
2665
Male, age 74, both hemispheres
24.8
1941
Male, age 53, unknown
24.3
2241
Male, age 72, unknown
23.6
1889
Female, age 72, unknown
22.6
2699
Male, age 18, unknown
22.2
1851
Male, age 51, unknown
22.1
1916
Female, age 42, unknown
21.1
2590
Female, age 75, unknown
19.7
2409
Female, age 72, unknown
18.1
Superior colliculus nTPM: 23.8
2664
Male, age 75, both hemispheres
30.3
2668
Female, age 75, unknown
29.2
2087
Female, age 72, unknown
24.2
1995
Male, age 72, unknown
23.1
1913
Female, age 42, unknown
23.0
2261
Male, age 18, unknown
22.3
1839
Male, age 51, unknown
22.2
1895
Male, age 76, right hemisphere
22.2
1796
Male, age 53, unknown
20.9
2587
Male, age 74, left hemisphere
20.9
Ventral tegmental area nTPM: 21.8
2021
Male, age 53, unknown
23.4
1942
Male, age 51, unknown
22.8
2223
Female, age 72, unknown
22.1
2218
Male, age 76, both hemispheres
22.0
2410
Female, age 72, unknown
20.8
1915
Female, age 42, unknown
19.7
MIDBRAIN - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Average nTPM
11.2
GTEx sample id
Sample description
nTPM
Brain - Substantia nigra Average nTPM: 11.2
Samples: 139
Max nTPM: 28.1
Min nTPM: 1.3
Std nTPM: 4.6
Median nTPM: 11.0
The Human Protein Atlas project is funded
