CEREBRAL CORTEX - Expression summary
Protein expression
Cerebral cortexi
h
m
l
n
Endothelial cells: Not detected
Glial cells: Not detected
Neuronal cells: High
Neuropil: Not detected
RNA expressioni
Consensus:27.9 nTPM
HPA:19.4 nTPM
HPA Brain:51.6 nTPM
HPA PFC Brain:10.0 nTPM
GTEx:27.9 nTPM
FANTOM5:125.1 Scaled Tags Per Million
Pig:59.7 nTPM
Mouse:140.0 nTPM
Allen mouse:18.6 Expression energy

CEREBRAL CORTEX - Antibody stainingi
Antibody HPA001847
Endothelial cells Not detected
Glial cells Medium
Neuronal cells High
Neuropil Not detected



CEREBRAL CORTEX - HPA RNA-seqi
Average nTPM 19.4
N/A
Male, age 5
Cerebral cortex sample 48
nTPM: 22.5
overview
Female, age 40
Cerebral cortex sample 105
nTPM: 17.2
Cell types%
Neuronal cells:
35

Glial cells and endothelial cells:
65
overview
Male, age 70
Cerebral cortex sample 106
nTPM: 18.4
Cell types%
Neuronal cells:
35

Glial cells and endothelial cells:
65

CEREBRAL CORTEX - HPA Brain RNA-seq
Max nTPM 51.6
Sample id Sample description nTPM
Angular gyrus
nTPM: 38.8
1866 Male, age 76, both hemispheres 54.5
2221 Female, age 67, right hemisphere 53.5
2260 Female, age 72, left hemisphere 44.8
1790 Male, age 76, right hemisphere 44.3
2602 Female, age 94, right hemisphere 36.1
2722 Male, age 61, left hemisphere 29.5
2265 Female, age 91, left hemisphere 24.9
2103 Male, age 75, left hemisphere 22.5
Anterior cingulate cortex, supragenual-dorsal
nTPM: 32.9
1896 Female, age 85, right hemisphere 41.6
2472 Male, age 75, left hemisphere 35.2
2547 Male, age 74, left hemisphere 30.3
2478 Female, age 67, right hemisphere 28.9
2342 Female, age 94, right hemisphere 28.5
Anterior cingulate cortex, supragenual-ventral
nTPM: 27.8
2538 Male, age 75, left hemisphere 31.9
1761 Male, age 74, left hemisphere 31.6
1950 Female, age 85, right hemisphere 30.1
1755 Female, age 94, right hemisphere 27.1
2479 Female, age 67, right hemisphere 18.5
Anterior insular cortex, dorsal
nTPM: 30.9
2506 Female, age 94, right hemisphere 40.6
2001 Male, age 76, right hemisphere 33.3
2670 Male, age 75, left hemisphere 26.1
2235 Female, age 91, right hemisphere 23.5
Anterior insular cortex, ventral
nTPM: 35.6
1852 Male, age 76, left hemisphere 43.4
1925 Female, age 91, left hemisphere 43.0
2757 Male, age 61, right hemisphere 41.1
2262 Female, age 67, right hemisphere 32.5
2507 Female, age 94, left hemisphere 29.4
2596 Male, age 75, left hemisphere 24.5
Area parastriata, inferior
nTPM: 33.1
1758 Female, age 72, right hemisphere 43.0
1760 Female, age 67, left hemisphere 41.1
1789 Male, age 76, right hemisphere 40.6
2268 Male, age 61, right hemisphere 36.4
2421 Female, age 91, left hemisphere 33.8
2509 Female, age 94, left hemisphere 19.7
2234 Male, age 75, left hemisphere 17.4
Area parastriata, parietal
nTPM: 27.3
2680 Female, age 94, right hemisphere 37.3
2236 Female, age 91, left hemisphere 29.7
2233 Male, age 61, right hemisphere 26.1
1785 Male, age 76, right hemisphere 25.6
2420 Male, age 75, left hemisphere 17.8
Area parastriata, superior
nTPM: 33.9
2881 Male, age 76, left hemisphere 71.9
1773 Female, age 91, left hemisphere 48.0
2419 Male, age 75, right hemisphere 27.7
2684 Female, age 67, left hemisphere 22.4
2604 Female, age 94, right hemisphere 18.8
2435 Male, age 61, left hemisphere 14.8
Area parastriata, temporal
nTPM: 36.7
2471 Male, age 75, left hemisphere 46.3
1804 Male, age 76, right hemisphere 43.9
2681 Female, age 94, right hemisphere 31.9
2424 Female, age 67, left hemisphere 31.5
2267 Male, age 61, right hemisphere 29.8
Area striata
nTPM: 38.1
2427 Female, age 91, left hemisphere 57.8
1753 Female, age 72, right hemisphere 45.7
2417 Male, age 61, right hemisphere 43.1
2679 Female, age 94, right hemisphere 35.8
1884 Male, age 76, left hemisphere 25.9
2002 Female, age 91, right hemisphere 20.4
Claustrum
nTPM: 28.1
2568 Male, age 61, both hemispheres 34.5
2284 Female, age 91, both hemispheres 32.4
2645 Female, age 72, unknown 31.8
2198 Male, age 80, both hemispheres 30.0
1956 Male, age 74, unknown 29.6
2491 Male, age 75, both hemispheres 28.0
2392 Female, age 94, both hemispheres 23.7
2292 Female, age 85, both hemispheres 22.2
2196 Female, age 79, unknown 21.0
Frontal eye field
nTPM: 39.2
2441 Male, age 75, left hemisphere 44.3
2543 Male, age 74, left hemisphere 41.1
2147 Male, age 61, left hemisphere 36.6
2761 Female, age 94, left hemisphere 34.8
Frontal operculum
nTPM: 28.8
2781 Female, age 85, right hemisphere 34.9
2348 Male, age 75, left hemisphere 27.9
2030 Male, age 61, right hemisphere 23.4
Fusiform gyrus
nTPM: 35.7
1807 Male, age 76, left hemisphere 53.7
2112 Male, age 80, both hemispheres 45.6
2433 Female, age 72, left hemisphere 38.3
2074 Female, age 91, left hemisphere 34.1
2784 Female, age 85, left hemisphere 29.1
2617 Female, age 94, left hemisphere 29.0
2431 Male, age 75, right hemisphere 20.1
Inferior frontal gyrus, opercular
nTPM: 38.9
2867 Male, age 75, left hemisphere 47.9
2873 Female, age 85, left hemisphere 44.3
2866 Male, age 61, right hemisphere 42.8
2865 Male, age 61, left hemisphere 41.3
2871 Female, age 94, left hemisphere 37.5
2872 Female, age 94, right hemisphere 37.4
2875 Female, age 67, left hemisphere 36.7
2868 Male, age 75, right hemisphere 34.5
2869 Male, age 74, left hemisphere 34.0
2874 Female, age 85, right hemisphere 32.6
Inferior parietal lobule
nTPM: 39.5
2418 Male, age 75, left hemisphere 46.2
2876 Male, age 76, right hemisphere 45.5
2599 Female, age 94, left hemisphere 37.7
2606 Female, age 67, right hemisphere 28.4
Inferior temporal gyrus
nTPM: 38.4
1808 Male, age 76, left hemisphere 49.2
1880 Male, age 80, right hemisphere 43.1
1965 Female, age 91, left hemisphere 40.2
1970 Female, age 85, right hemisphere 34.0
2430 Male, age 75, right hemisphere 33.9
2689 Female, age 94, right hemisphere 30.1
Intraparietal deep sulcus
nTPM: 33.0
2798 Male, age 76, left hemisphere 49.8
2230 Male, age 61, right hemisphere 38.5
2669 Male, age 75, left hemisphere 35.1
2102 Female, age 91, left hemisphere 29.5
2600 Female, age 94, right hemisphere 24.1
2607 Female, age 67, right hemisphere 20.9
Lingual gyrus
nTPM: 32.4
2838 Male, age 80, right hemisphere 43.6
1893 Male, age 76, left hemisphere 39.5
2688 Male, age 75, right hemisphere 32.4
2618 Female, age 94, left hemisphere 24.1
2073 Female, age 85, left hemisphere 22.4
Middle cingulate cortex
nTPM: 29.5
2357 Female, age 67, right hemisphere 48.8
2028 Female, age 85, left hemisphere 26.9
2539 Male, age 75, left hemisphere 25.7
2640 Female, age 94, right hemisphere 23.1
2633 Male, age 74, left hemisphere 22.8
Middle temporal gyrus
nTPM: 36.0
1799 Male, age 76, left hemisphere 44.8
2034 Female, age 91, right hemisphere 41.4
1819 Male, age 80, right hemisphere 38.5
2611 Male, age 75, right hemisphere 31.9
2616 Female, age 94, left hemisphere 23.6
Occipital cortex
nTPM: 46.8
2426 Male, age 75, midline 55.6
1842 Male, age 76, right hemisphere 55.5
2470 Male, age 75, right hemisphere 49.4
2608 Female, age 67, both hemispheres 43.5
2677 Female, age 67, right hemisphere 30.1
Olfactory area
nTPM: 31.5
2756 Female, age 67, right hemisphere 44.4
2222 Female, age 67, right hemisphere 42.3
1805 Female, age 85, right hemisphere 33.4
2440 Male, age 75, left hemisphere 26.2
2352 Female, age 94, right hemisphere 23.8
2542 Male, age 74, left hemisphere 18.7
Olfactory tubercle
nTPM: 35.7
1998 Female, age 91, both hemispheres 41.0
1846 Male, age 80, right hemisphere 37.8
2487 Female, age 94, left hemisphere 33.4
2856 Male, age 75, right hemisphere 30.5
Orbitofrontal gyrus, anterior
nTPM: 30.7
2863 Female, age 85, right hemisphere 58.7
2862 Female, age 85, left hemisphere 18.3
2864 Female, age 67, left hemisphere 15.2
Paracentral lobule, anterior
nTPM: 41.0
2474 Male, age 74, left hemisphere 48.2
1754 Male, age 75, left hemisphere 42.9
1926 Male, age 61, left hemisphere 40.8
2340 Female, age 67, right hemisphere 39.7
1776 Female, age 85, right hemisphere 38.8
2638 Female, age 94, right hemisphere 35.8
Paracentral lobule, posterior
nTPM: 32.8
1775 Female, age 85, right hemisphere 45.9
2446 Male, age 75, left hemisphere 31.9
1764 Male, age 74, right hemisphere 31.4
2345 Male, age 61, left hemisphere 30.3
2551 Female, age 94, right hemisphere 24.6
Parietal operculum
nTPM: 34.0
2356 Female, age 67, right hemisphere 38.0
2719 Male, age 75, left hemisphere 35.1
2552 Female, age 94, right hemisphere 32.7
1763 Male, age 74, left hemisphere 30.2
Parieto-insular cortex
nTPM: 41.5
2831 Male, age 76, right hemisphere 59.3
1976 Female, age 91, right hemisphere 54.7
2232 Male, age 61, right hemisphere 37.7
2671 Male, age 75, left hemisphere 31.5
2508 Female, age 94, right hemisphere 24.5
Parieto-occipital transitional area
nTPM: 32.0
1784 Male, age 76, right hemisphere 44.2
2674 Female, age 94, right hemisphere 33.6
2468 Male, age 75, left hemisphere 33.5
2270 Male, age 61, right hemisphere 33.4
2683 Female, age 67, left hemisphere 15.2
Piriform cortex
nTPM: 7.5
2347 Male, age 75, right hemisphere 8.5
2153 Female, age 85, left hemisphere 6.5
Postcentral gyrus
nTPM: 47.7
2533 Male, age 75, right hemisphere 47.7
Postcentral gyrus, dorsal
nTPM: 34.0
1836 Female, age 85, right hemisphere 42.8
2544 Male, age 74, left hemisphere 40.5
2151 Male, age 61, left hemisphere 37.3
2350 Male, age 75, left hemisphere 29.0
2339 Female, age 67, right hemisphere 28.2
2477 Female, age 94, right hemisphere 26.3
Postcentral gyrus, middle
nTPM: 45.6
2545 Male, age 74, left hemisphere 53.9
2146 Female, age 67, right hemisphere 50.2
2444 Male, age 75, left hemisphere 46.5
1897 Female, age 85, right hemisphere 43.5
2248 Male, age 61, left hemisphere 33.8
Postcentral gyrus, ventral
nTPM: 34.9
2445 Male, age 75, left hemisphere 44.7
2836 Female, age 94, right hemisphere 32.0
2024 Female, age 85, right hemisphere 28.1
Posterior cingulate cortex
nTPM: 33.3
2553 Female, age 94, right hemisphere 37.6
2473 Male, age 75, left hemisphere 35.6
1759 Male, age 74, right hemisphere 26.6
Posterior cingulate cortex, dorsal
nTPM: 27.2
2076 Female, age 85, right hemisphere 36.0
2540 Male, age 75, right hemisphere 30.0
2641 Female, age 94, right hemisphere 29.0
2634 Male, age 74, left hemisphere 25.5
2343 Male, age 61, left hemisphere 24.7
2556 Female, age 67, right hemisphere 18.0
Posterior cingulate cortex, ventral
nTPM: 29.2
1994 Female, age 85, right hemisphere 36.6
2346 Male, age 61, left hemisphere 33.1
2635 Male, age 74, left hemisphere 31.2
1762 Female, age 94, right hemisphere 30.7
2448 Female, age 67, right hemisphere 22.1
2541 Male, age 75, right hemisphere 21.7
Posterior insular cortex
nTPM: 39.8
1823 Male, age 76, right hemisphere 52.5
2832 Female, age 91, right hemisphere 44.7
2511 Female, age 67, right hemisphere 40.7
2231 Male, age 61, left hemisphere 37.9
2603 Female, age 94, left hemisphere 31.6
2597 Male, age 75, left hemisphere 31.3
Precentral gyrus
nTPM: 40.4
2557 Male, age 75, right hemisphere 40.4
Precentral gyrus, dorsal
nTPM: 34.4
2354 Female, age 67, right hemisphere 45.5
1756 Male, age 74, left hemisphere 34.2
2442 Male, age 75, left hemisphere 30.3
2476 Female, age 94, right hemisphere 27.5
Precentral gyrus, middle
nTPM: 37.2
1969 Female, age 67, right hemisphere 52.2
1909 Male, age 61, left hemisphere 44.6
2549 Female, age 94, right hemisphere 37.0
2443 Male, age 75, left hemisphere 28.8
2475 Male, age 74, right hemisphere 23.6
Precentral gyrus, ventral
nTPM: 35.5
2678 Male, age 74, left hemisphere 40.3
2630 Male, age 75, left hemisphere 38.8
2662 Female, age 67, right hemisphere 31.5
2550 Female, age 94, right hemisphere 31.4
Precuneus
nTPM: 31.2
1780 Female, age 91, right hemisphere 44.4
1782 Male, age 76, right hemisphere 37.9
2594 Male, age 61, left hemisphere 32.8
2673 Female, age 94, right hemisphere 27.4
2510 Female, age 67, right hemisphere 23.2
2467 Male, age 75, right hemisphere 21.7
Premotor cortex, dorsal
nTPM: 32.8
1878 Female, age 85, right hemisphere 44.5
2027 Male, age 61, left hemisphere 37.2
2536 Male, age 75, left hemisphere 28.5
2631 Male, age 74, left hemisphere 28.5
2554 Female, age 67, right hemisphere 25.3
Premotor cortex, ventral
nTPM: 39.9
1881 Female, age 85, right hemisphere 48.4
1777 Female, age 67, left hemisphere 45.2
2637 Female, age 94, right hemisphere 42.6
1779 Male, age 61, left hemisphere 41.5
1757 Male, age 74, left hemisphere 31.0
2349 Male, age 75, left hemisphere 30.4
Retrosplenial cortex
nTPM: 30.8
1914 Male, age 76, right hemisphere 34.6
1951 Male, age 61, right hemisphere 31.9
2675 Female, age 94, left hemisphere 25.8
Subcentral gyrus, S2
nTPM: 37.3
2839 Female, age 94, right hemisphere 41.1
2072 Male, age 61, left hemisphere 41.0
2762 Male, age 74, left hemisphere 40.8
1964 Female, age 85, right hemisphere 36.3
2555 Female, age 67, right hemisphere 32.6
2351 Male, age 75, left hemisphere 31.9
Superior parietal lobule
nTPM: 34.6
1800 Male, age 76, right hemisphere 42.3
2229 Male, age 61, right hemisphere 37.3
1992 Female, age 91, right hemisphere 33.8
2672 Female, age 94, right hemisphere 32.1
2605 Female, age 67, right hemisphere 27.5
Superior temporal gyrus
nTPM: 43.7
1843 Male, age 76, left hemisphere 54.6
1844 Female, age 91, left hemisphere 49.3
2025 Male, age 80, right hemisphere 41.1
2687 Male, age 75, right hemisphere 37.5
2615 Female, age 94, left hemisphere 36.0
Supplementary motor cortex
nTPM: 36.8
2537 Male, age 75, left hemisphere 51.6
1993 Male, age 61, left hemisphere 37.3
2548 Female, age 94, right hemisphere 33.4
2632 Male, age 74, left hemisphere 24.9
Supramarginal gyrus
nTPM: 41.3
2513 Female, age 72, left hemisphere 49.1
1798 Male, age 76, right hemisphere 48.2
1991 Female, age 91, right hemisphere 39.3
2415 Male, age 61, left hemisphere 39.3
2601 Female, age 94, left hemisphere 30.8
Temporal pole
nTPM: 31.9
1853 Female, age 85, right hemisphere 40.5
1832 Female, age 91, left hemisphere 37.6
1826 Male, age 76, right hemisphere 35.7
2612 Female, age 94, left hemisphere 24.7
2518 Male, age 75, right hemisphere 20.9
Temporo-insular cortex, parainsular gyrus
nTPM: 29.4
1802 Male, age 76, left hemisphere 39.9
2416 Male, age 61, right hemisphere 30.0
2264 Female, age 91, right hemisphere 28.6
2676 Female, age 94, right hemisphere 28.5
2598 Male, age 75, left hemisphere 26.0
2512 Female, age 67, right hemisphere 23.3
Temporo-occipital transitional zone
nTPM: 51.6
1900 Male, age 76, left hemisphere 66.0
1793 Male, age 80, right hemisphere 54.7
2251 Female, age 85, right hemisphere 34.3
Transversal temporal gyrus, anterior
nTPM: 47.1
1910 Male, age 80, right hemisphere 58.2
1809 Male, age 76, right hemisphere 51.9
1888 Female, age 91, left hemisphere 49.8
2522 Female, age 94, left hemisphere 38.1
2610 Male, age 75, right hemisphere 37.6
Transversal temporal gyrus, posterior
nTPM: 40.7
2833 Male, age 80, right hemisphere 60.9
1922 Male, age 76, left hemisphere 45.3
1967 Female, age 91, right hemisphere 42.9
2520 Male, age 75, right hemisphere 27.3
2614 Female, age 94, left hemisphere 27.3

CEREBRAL CORTEX - HPA PFC Brain RNA-seq
Max nTPM 10.0
Sample id Sample description nTPM
Anterior cingulate gyrus, pregenual-dorsal
nTPM: 5.6
1516 Female, age 85, left hemisphere 11.3
1511 Male, age 61, right hemisphere 9.6
1510 Male, age 61, left hemisphere 8.0
1513 Male, age 74, left hemisphere 4.1
1515 Female, age 94, right hemisphere 3.9
1512 Male, age 75, left hemisphere 3.8
1514 Male, age 74, right hemisphere 3.8
1517 Female, age 67, left hemisphere 3.1
1518 Female, age 67, right hemisphere 2.9
Anterior cingulate gyrus, pregenual-ventral
nTPM: 6.2
1519 Male, age 61, left hemisphere 7.9
1521 Male, age 74, left hemisphere 6.9
1523 Female, age 67, left hemisphere 6.4
1522 Male, age 74, right hemisphere 5.4
1520 Male, age 75, right hemisphere 4.5
Anterior cingulate gyrus, subgenual
nTPM: 6.1
1529 Female, age 85, left hemisphere 13.2
1524 Male, age 61, left hemisphere 8.6
1527 Male, age 74, left hemisphere 4.7
1528 Male, age 74, right hemisphere 4.5
1525 Male, age 75, left hemisphere 4.3
1530 Female, age 67, right hemisphere 3.8
1526 Male, age 75, right hemisphere 3.2
Dorsolateral prefrontal cortex
nTPM: 5.8
1444 Male, age 75, left hemisphere 9.2
1449 Female, age 85, right hemisphere 7.5
1446 Male, age 74, right hemisphere 5.5
1445 Male, age 75, right hemisphere 5.4
1448 Female, age 94, right hemisphere 4.4
1450 Female, age 67, right hemisphere 4.4
1447 Female, age 94, left hemisphere 4.1
Dorsomedial prefrontal cortex
nTPM: 6.5
1439 Male, age 61, left hemisphere 9.4
1440 Male, age 61, right hemisphere 8.9
1441 Male, age 75, left hemisphere 5.1
1442 Male, age 75, right hemisphere 4.5
1443 Female, age 67, right hemisphere 4.5
Frontal cortex
nTPM: 8.9
1581 Female, age 85, right hemisphere 19.8
1580 Female, age 85, left hemisphere 16.3
1573 Male, age 61, right hemisphere 12.4
1575 Male, age 75, right hemisphere 9.5
1572 Male, age 61, left hemisphere 8.1
1577 Male, age 74, right hemisphere 6.7
1582 Female, age 67, left hemisphere 6.5
1574 Male, age 75, left hemisphere 6.1
1579 Female, age 94, right hemisphere 5.9
1578 Female, age 94, left hemisphere 5.5
1576 Male, age 74, left hemisphere 5.3
1583 Female, age 67, right hemisphere 5.2
Frontomarginal cortex
nTPM: 7.3
1471 Female, age 85, left hemisphere 15.3
1465 Male, age 61, left hemisphere 12.0
1466 Male, age 61, right hemisphere 11.7
1467 Male, age 75, right hemisphere 8.3
1470 Female, age 94, right hemisphere 4.7
1469 Female, age 94, left hemisphere 4.6
1468 Male, age 74, left hemisphere 4.3
1473 Female, age 67, right hemisphere 3.2
1472 Female, age 67, left hemisphere 1.8
Frontopolar cortex
nTPM: 7.4
1459 Male, age 61, right hemisphere 14.3
1458 Male, age 61, left hemisphere 13.1
1461 Male, age 75, right hemisphere 7.6
1460 Male, age 75, left hemisphere 6.5
1462 Female, age 94, left hemisphere 3.7
1463 Female, age 67, left hemisphere 3.2
1464 Female, age 67, right hemisphere 3.1
Gyrus rectus
nTPM: 6.8
1475 Male, age 61, right hemisphere 13.7
1480 Female, age 85, left hemisphere 10.1
1474 Male, age 61, left hemisphere 8.2
1479 Female, age 94, right hemisphere 5.8
1476 Male, age 75, left hemisphere 5.5
1478 Female, age 94, left hemisphere 4.8
1481 Female, age 67, left hemisphere 3.5
1477 Male, age 75, right hemisphere 2.4
Inferior frontal gyrus, orbital
nTPM: 6.7
1508 Female, age 85, right hemisphere 12.9
1501 Male, age 61, right hemisphere 12.6
1500 Male, age 61, left hemisphere 10.6
1502 Male, age 75, left hemisphere 6.8
1504 Male, age 74, left hemisphere 6.8
1503 Male, age 75, right hemisphere 5.1
1506 Female, age 94, left hemisphere 4.0
1507 Female, age 85, left hemisphere 4.0
1509 Female, age 67, right hemisphere 2.8
1505 Male, age 74, right hemisphere 1.2
Inferior frontal gyrus, triangular
nTPM: 6.5
1548 Female, age 85, right hemisphere 11.4
1543 Male, age 61, right hemisphere 10.6
1542 Male, age 61, left hemisphere 9.8
1545 Male, age 74, right hemisphere 6.5
1549 Female, age 67, left hemisphere 4.9
1544 Male, age 75, right hemisphere 3.3
1547 Female, age 85, left hemisphere 2.9
1546 Female, age 94, right hemisphere 2.7
Orbitofrontal gyrus, lateral
nTPM: 6.2
1493 Male, age 61, right hemisphere 12.1
1498 Female, age 85, right hemisphere 9.0
1494 Male, age 75, left hemisphere 6.3
1497 Female, age 85, left hemisphere 5.1
1495 Female, age 94, left hemisphere 3.9
1496 Female, age 94, right hemisphere 3.8
1499 Female, age 67, right hemisphere 2.9
Orbitofrontal gyrus, medial
nTPM: 7.0
1490 Female, age 85, right hemisphere 14.1
1489 Female, age 85, left hemisphere 11.3
1482 Male, age 61, left hemisphere 11.0
1485 Male, age 74, left hemisphere 7.8
1488 Female, age 94, right hemisphere 5.4
1483 Male, age 75, left hemisphere 5.0
1486 Male, age 74, right hemisphere 5.0
1487 Female, age 94, left hemisphere 4.9
1492 Female, age 67, right hemisphere 4.8
1484 Male, age 75, right hemisphere 4.3
1491 Female, age 67, left hemisphere 3.6
Orbitofrontal gyrus, posterior
nTPM: 6.5
1531 Male, age 61, left hemisphere 13.2
1532 Male, age 61, right hemisphere 12.1
1538 Female, age 85, left hemisphere 9.8
1533 Male, age 75, left hemisphere 7.7
1539 Female, age 85, right hemisphere 7.7
1536 Female, age 94, left hemisphere 4.2
1537 Female, age 94, right hemisphere 4.0
1540 Female, age 67, left hemisphere 3.7
1541 Female, age 67, right hemisphere 3.3
1534 Male, age 75, right hemisphere 2.8
1535 Male, age 74, left hemisphere 2.8
Subcallosal gyrus
nTPM: 8.4
1550 Male, age 61, left hemisphere 17.6
1558 Female, age 85, left hemisphere 16.5
1559 Female, age 85, right hemisphere 16.3
1551 Male, age 61, right hemisphere 10.5
1557 Female, age 94, right hemisphere 5.8
1554 Male, age 74, left hemisphere 5.6
1556 Female, age 94, left hemisphere 5.6
1561 Female, age 67, right hemisphere 5.4
1555 Male, age 74, right hemisphere 5.3
1553 Male, age 75, right hemisphere 4.7
1560 Female, age 67, left hemisphere 3.7
1552 Male, age 75, left hemisphere 3.5
Superior frontal gyrus
nTPM: 10.0
1569 Female, age 85, left hemisphere 20.2
1562 Male, age 61, left hemisphere 13.6
1570 Female, age 85, right hemisphere 13.3
1563 Male, age 61, right hemisphere 13.2
1564 Male, age 75, left hemisphere 9.0
1565 Male, age 75, right hemisphere 7.8
1566 Male, age 74, right hemisphere 6.2
1568 Female, age 94, right hemisphere 5.9
1567 Female, age 94, left hemisphere 5.7
1571 Female, age 67, right hemisphere 5.5
Temporal cortex
nTPM: 8.2
1596 Female, age 85, right hemisphere 14.3
1590 Male, age 61, right hemisphere 11.8
1592 Male, age 74, left hemisphere 7.2
1595 Female, age 94, right hemisphere 7.1
1591 Male, age 75, right hemisphere 6.6
1594 Female, age 94, left hemisphere 5.4
1593 Male, age 74, right hemisphere 4.8
Ventrolateral prefrontal cortex
nTPM: 4.5
1455 Female, age 85, right hemisphere 8.0
1452 Male, age 74, left hemisphere 4.5
1453 Male, age 74, right hemisphere 4.5
1457 Female, age 67, right hemisphere 4.5
1451 Male, age 75, right hemisphere 4.4
1454 Female, age 94, left hemisphere 3.4
1456 Female, age 67, left hemisphere 2.3
Ventromedial prefrontal cortex
nTPM: 7.8
1436 Female, age 85, left hemisphere 14.6
1433 Male, age 61, right hemisphere 10.4
1437 Female, age 85, right hemisphere 10.0
1432 Male, age 61, left hemisphere 8.6
1434 Male, age 75, right hemisphere 5.2
1435 Female, age 94, right hemisphere 3.6
1438 Female, age 67, left hemisphere 2.6

CEREBRAL CORTEX - GTEx RNA-seqi
Average nTPM 27.9
GTEx sample id Sample description nTPM
Brain - Anterior cingulate cortex (BA24)
Average nTPM: 21.5
Samples: 176

Max nTPM: 46.7
Min nTPM: 5.1
Std nTPM: 9.8
Median nTPM: 20.8
GTEX-WL46-0011-R3A-SM-3TW8E 50-59 years, male 46.7
GTEX-14PN4-0011-R3b-SM-686ZU 50-59 years, male 44.2
GTEX-N7MS-0011-R3a-SM-33HC6 60-69 years, male 42.4
GTEX-131XH-0011-R3b-SM-5DUWM 50-59 years, male 41.2
GTEX-Z93S-0011-R3b-SM-4RGNH 50-59 years, male 41.0
GTEX-PVOW-0011-R3A-SM-32PKX 40-49 years, male 40.7
GTEX-1B8L1-0011-R3a-SM-7EPIO 60-69 years, male 40.4
GTEX-P44G-0011-R3A-SM-2I3FC 30-39 years, male 40.0
GTEX-Q2AG-0011-R3A-SM-2HMJ9 40-49 years, female 39.9
GTEX-WZTO-0011-R3B-SM-3NMC6 40-49 years, male 39.4
GTEX-1F75A-0011-R3b-SM-ARL8K 50-59 years, male 38.0
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Brain - Cortex
Average nTPM: 21.3
Samples: 255

Max nTPM: 44.1
Min nTPM: 0.4
Std nTPM: 7.8
Median nTPM: 21.0
GTEX-PVOW-2526-SM-2XCF7 40-49 years, male 44.1
GTEX-1B8L1-3026-SM-7EPHK 60-69 years, male 42.8
GTEX-1B933-3126-SM-7P8RL 50-59 years, female 42.8
GTEX-TSE9-3026-SM-3DB76 60-69 years, female 41.5
GTEX-P44G-2426-SM-2I5ER 30-39 years, male 40.7
GTEX-WVLH-3026-SM-3MJG9 50-59 years, male 37.3
GTEX-QMR6-1426-SM-32PLA 50-59 years, male 35.3
GTEX-1HCVE-3026-SM-CL54G 50-59 years, male 35.2
GTEX-15EO6-3026-SM-7KUMA 50-59 years, male 35.1
GTEX-1KWVE-2326-SM-D4P3N 30-39 years, male 34.7
GTEX-Z93S-2926-SM-57WB9 50-59 years, male 34.4
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Brain - Frontal Cortex (BA9)
Average nTPM: 27.9
Samples: 209

Max nTPM: 58.4
Min nTPM: 2.4
Std nTPM: 11.0
Median nTPM: 29.0
GTEX-WL46-0011-R10A-SM-3MJFQ 50-59 years, male 58.4
GTEX-T6MN-0011-R10A-SM-32QP7 50-59 years, male 50.4
GTEX-Q2AG-0011-R10A-SM-2HMLA 40-49 years, female 50.2
GTEX-1B8L1-0011-R10b-SM-7P8Q4 60-69 years, male 50.1
GTEX-14PN4-0011-R10b-SM-69LP2 50-59 years, male 49.2
GTEX-PVOW-0011-R10A-SM-EXOHB 40-49 years, male 48.2
GTEX-QDT8-0011-R10A-SM-32PKG 30-39 years, female 45.6
GTEX-1EMGI-0011-R10a-SM-9OSWY 60-69 years, male 45.5
GTEX-QMR6-0011-R10A-SM-32PKO 50-59 years, male 45.3
GTEX-11DXY-0011-R10b-SM-DO12C 60-69 years, male 44.5
GTEX-P44G-0011-R10A-SM-2I3FF 30-39 years, male 44.4
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CEREBRAL CORTEX - FANTOM5 CAGEi
Max Scaled Tags Per Million 125.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Occipital cortex
Scaled Tags Per Million: 66.3
FF:10163-103B1 76 years, female 66.3
Postcentral gyrus
Scaled Tags Per Million: 91.6
FF:10032-101E5 44-52 years, mixed 91.6
Frontal lobe
Scaled Tags Per Million: 89.7
FF:10040-101F4 32-61 years, mixed 89.7
Insula
Scaled Tags Per Million: 68.2
FF:10039-101F3 20-68 years, mixed 68.2
Medial frontal gyrus
Scaled Tags Per Million: 65.2
FF:10150-102I6 76 years, female 65.2
Medial temporal gyrus
Scaled Tags Per Million: 82.2
FF:10183-103D3 60 years, female 100.5
FF:10156-103A3 76 years, female 63.9
Occipital lobe
Scaled Tags Per Million: 125.1
FF:10076-102A4 27 years, male 125.1
Occipital pole
Scaled Tags Per Million: 96.6
FF:10036-101E9 22-68 years, mixed 96.6
Paracentral gyrus
Scaled Tags Per Million: 93.7
FF:10035-101E8 22-69 years, mixed 93.7
Parietal lobe
Scaled Tags Per Million: 97.0
FF:10171-103B9 60 years, female 118.6
FF:10034-101E7 35-89 years, mixed 86.2
FF:10157-103A4 76 years, female 86.0
Temporal lobe
Scaled Tags Per Million: 64.2
FF:10031-101E4 32-61 years, mixed 64.2

CEREBRAL CORTEX - Pig RNA-seqi
Average nTPM 59.7
Pig sample Sample description nTPM
Occipital cortex
nTPM: 45.5
Samples: 4

Max nTPM: 49.1
Min nTPM: 42.3
Sample A Female 42.3
Sample B Female 49.1
Sample C Male 48.3
Sample D Male 42.4
Retrosplenial cortex
nTPM: 52.0
Samples: 4

Max nTPM: 56.6
Min nTPM: 44.3
Sample A Female 44.3
Sample B Female 54.6
Sample C Male 56.6
Sample D Male 52.4
Cingulate cortex
nTPM: 52.5
Samples: 4

Max nTPM: 56.7
Min nTPM: 48.0
Sample A Female 48.0
Sample B Female 50.2
Sample C Male 55.0
Sample D Male 56.7
Insular cortex
nTPM: 47.8
Samples: 4

Max nTPM: 54.5
Min nTPM: 41.8
Sample A Female 54.5
Sample B Female 48.6
Sample C Male 46.4
Sample D Male 41.8
Motor cortex
nTPM: 59.7
Samples: 4

Max nTPM: 70.3
Min nTPM: 46.9
Sample A Female 70.3
Sample B Female 51.9
Sample C Male 69.5
Sample D Male 46.9
Prefrontal cortex
nTPM: 57.4
Samples: 4

Max nTPM: 77.4
Min nTPM: 47.5
Sample A Female 77.4
Sample B Female 47.5
Sample C Male 56.0
Sample D Male 48.7
Somatosensory cortex
nTPM: 46.4
Samples: 3

Max nTPM: 48.2
Min nTPM: 43.5
Sample B Female 48.2
Sample C Male 47.4
Sample D Male 43.5
Temporal cortex
nTPM: 50.5
Samples: 4

Max nTPM: 55.5
Min nTPM: 42.4
Sample A Female 55.5
Sample B Female 51.3
Sample C Male 52.9
Sample D Male 42.4

CEREBRAL CORTEX - Mouse RNA-seqi
Average nTPM 140.0
Mouse sample Sample description nTPM
Occipital cortex
nTPM: 140.0
Samples: 4

Max nTPM: 144.2
Min nTPM: 133.5
Sample A Male 133.5
Sample B Male 144.2
Sample C Female 142.4
Sample D Female 139.9
Frontal cortex
nTPM: 135.3
Samples: 4

Max nTPM: 139.8
Min nTPM: 133.0
Sample A Male 133.4
Sample B Male 133.0
Sample C Female 139.8
Sample D Female 134.9
Retrosplenial and cingulate cortex
nTPM: 127.8
Samples: 4

Max nTPM: 137.3
Min nTPM: 115.6
Sample A Male 125.9
Sample B Male 132.4
Sample C Female 137.3
Sample D Female 115.6
Somatosensory cortex
nTPM: 135.1
Samples: 4

Max nTPM: 141.8
Min nTPM: 128.9
Sample A Male 128.9
Sample B Male 141.8
Sample C Female 134.5
Sample D Female 135.0

CEREBRAL CORTEX - Allen Mouse ISHi
Max Expression energy 18.6
Allen experiment id Experiment description Expression energy
Cerebral cortex
Expression energy: 18.6
73732150 Antisense, RP_051121_04_A08, Mouse strain C57BL/6J (56 days, male) 19.7
68161484 Antisense, RP_041122_01_F03, Mouse strain C57BL/6J (56 days, male) 17.4

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