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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA038175
Strong membranous and cytoplasmic positivity was displayed in renal glomeruli, endothelial cells and a fraction of smooth muscle cells. Subsets of cells in gastric glands, bone marrow poietic cells and seminal vesicle showed strong cytoplasmic staining. Moderate nuclear staining was showed in lymphoid cells outside reaction centra and white pulp of spleen. Moderate cytoplasmic and/or membranous immunoreactivity was observed in heart muscle, alveolar cells, placental trophoblastic cells and thyroid. Remaining normal tissues were weakly stained or negative.
HPA057587
Normal tissues displayed weak to moderate cytoplasmic staining. Salivary gland, exocrine pancreas, Leydig cells and epididymis were strongly stained. Glial cells were negative.
The Human Protein Atlas project is funded
