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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA004835
Strong cytoplasmic and membranous positivity was observed in subset of immune cells in essentially all tissues. Spermatozoa were also distinctly stained. Moderate cytoplasmic staining was displayed in smooth muscle cells, myoepithelial cells in breast and cells in renal glomeruli. Remaining normal cells were weakly stained or negative.
HPA073497
Strong cytoplasmic positivity was observed in subsets of immune cells, endothelial cells, myoepithelial cells in breast and smooth muscle cells. Remaining normal tissues were weakly stained or negative.
CAB009321
Most tissues showed weak to moderate cytoplasmic staining, except for epidermal cells showed strong staining. Myocytes and cells in CNS were generally negative.
CAB075747
Strong cytoplasmic positivity was observed in subsets of immune cells and in blood vessels. Myoepithelial cells in the mammary gland and smooth muscle cells were moderately stained. Most other normal cells were negative.
The Human Protein Atlas project is funded
