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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Not detected
Hepatocytes:
Not detected
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
40.0
nTPM
HPA:
40.0
nTPM
GTEx:
31.7
nTPM
FANTOM5:
66.7
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA070820
Cholangiocytes
Not detected
Hepatocytes
Not detected
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPM
40.0
Female, age 60
Liver sample 21 nTPM: 43.6
Male, age 54
Liver sample 23 nTPM: 50.5
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 40.6
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 38.2
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 43.5
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 35.2
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 41.8
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 35.9
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 33.3
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 37.5
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Average nTPM
31.7
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 31.7
Samples: 226
Max nTPM: 128.1
Min nTPM: 13.4
Std nTPM: 16.6
Median nTPM: 27.2
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
128.1
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
101.1
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
98.9
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
94.6
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
89.5
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
81.0
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
76.0
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
72.5
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
71.8
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
69.0
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
68.9
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
67.2
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
66.8
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
60.3
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
60.1
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
59.5
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
58.3
GTEX-14PJO-1726-SM-68719
60-69 years, male
58.1
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
58.1
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
52.9
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
50.4
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
50.0
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
49.8
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
49.1
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
48.9
GTEX-QESD-2026-SM-447BI
20-29 years, male
48.8
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
48.5
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
47.8
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
46.3
GTEX-Q734-0326-SM-48U15
40-49 years, female
45.2
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
44.8
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
44.4
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
44.0
GTEX-QEL4-1226-SM-447A4
50-59 years, male
43.4
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
43.3
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
43.0
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
42.2
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
42.2
GTEX-14XAO-0226-SM-68728
60-69 years, female
41.5
GTEX-S32W-1926-SM-4AD63
50-59 years, female
40.7
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
39.7
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
39.0
GTEX-11GSP-0626-SM-5986T
60-69 years, female
38.4
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
38.4
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
38.0
GTEX-X261-1726-SM-4PQYT
50-59 years, male
38.0
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
38.0
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
38.0
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
37.6
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
37.6
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
37.4
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
37.1
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
36.7
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
35.5
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
35.1
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
34.9
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
34.5
GTEX-1B932-1426-SM-793AN
40-49 years, female
34.4
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
34.3
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
34.2
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
34.0
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
33.9
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
33.6
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
33.3
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
33.2
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
33.1
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
33.0
GTEX-RU72-1426-SM-46MUF
50-59 years, female
32.8
GTEX-S33H-1626-SM-4AD68
30-39 years, male
32.8
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
32.7
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
32.6
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
32.6
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
32.4
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
32.4
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
32.3
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
32.2
GTEX-P78B-1326-SM-3P611
40-49 years, female
31.9
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
31.9
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
31.6
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
31.4
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
31.3
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
31.0
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
30.8
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
30.8
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
30.8
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
30.6
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
30.2
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
29.9
GTEX-18A66-2026-SM-7189C
60-69 years, male
29.9
GTEX-REY6-1226-SM-48FDR
60-69 years, male
29.9
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
29.8
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
29.4
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
29.3
GTEX-12696-0826-SM-5EGGE
60-69 years, male
29.2
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
29.2
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
29.2
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
29.1
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
29.0
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
29.0
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
28.8
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
28.5
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
28.5
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
28.4
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
28.3
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
28.1
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
28.1
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
27.8
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
27.8
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
27.8
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
27.6
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
27.4
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
27.3
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
27.2
GTEX-O5YV-0726-SM-EV798
60-69 years, female
27.2
GTEX-144GL-1426-SM-79OMA
50-59 years, male
27.0
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
27.0
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
26.8
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
26.8
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
26.7
GTEX-14PHX-0526-SM-664NW
50-59 years, male
26.4
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
26.2
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
26.1
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
26.1
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
25.9
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
25.8
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
25.7
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
25.7
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
25.6
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
25.5
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
25.5
GTEX-13113-1326-SM-5GCOI
60-69 years, female
25.4
GTEX-14E7W-1526-SM-6871X
70-79 years, male
25.3
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
25.0
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
25.0
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
24.9
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
24.7
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
24.7
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
24.4
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
24.4
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
24.3
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
24.3
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
24.3
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
24.3
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
24.2
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
24.1
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
24.0
GTEX-1B933-1226-SM-731DW
50-59 years, female
23.9
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
23.8
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
23.8
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
23.7
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
23.5
GTEX-R53T-0326-SM-48FEC
50-59 years, female
23.3
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
23.3
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
23.1
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
22.9
GTEX-14JG1-1626-SM-664NH
40-49 years, male
22.7
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
22.7
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
22.7
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
22.6
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
22.4
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
22.3
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
22.3
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
22.2
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
22.2
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
22.2
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
22.1
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
22.0
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
21.8
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
21.7
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
21.7
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
21.6
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
21.2
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
21.2
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
21.1
GTEX-1399T-0826-SM-5IFES
60-69 years, male
20.8
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
20.7
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
20.6
GTEX-18A7A-1526-SM-72D69
50-59 years, female
20.6
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
20.5
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
20.3
GTEX-17F96-1226-SM-79OK2
70-79 years, male
20.3
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
20.2
GTEX-YECK-1926-SM-4W21H
60-69 years, male
20.2
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
20.1
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
20.1
GTEX-13112-1426-SM-5EGH8
50-59 years, male
20.0
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
19.9
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
19.7
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
19.6
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
19.6
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
19.5
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
19.4
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
19.3
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
19.0
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
18.8
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
18.8
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
18.6
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
18.6
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
18.5
GTEX-17HHE-0126-SM-79398
50-59 years, male
18.5
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
18.4
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
18.2
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
18.2
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
18.0
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
17.4
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
17.4
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
17.2
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
16.9
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
16.8
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
16.7
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
16.6
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
16.5
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
16.4
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
16.4
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
16.3
GTEX-18465-1626-SM-7LG6N
50-59 years, male
16.2
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
16.0
GTEX-11ZUS-2526-SM-59872
30-39 years, male
15.6
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
15.5
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
15.2
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
15.0
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
14.9
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
14.8
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
14.8
GTEX-RN64-1826-SM-48FDV
50-59 years, male
14.5
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
13.4
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
The Human Protein Atlas project is funded
