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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA027709
Normal tissue showed weak to moderate cytoplasmic staining with cases of membranous positivity. Ciliated cells and trophoblastic cells displayed strong immunoreactivity. Gastrointestinal tract, hepatocytes and lymphoid tissue were negative.
HPA028478
Moderate to strong cytoplasmic positivity with a granular pattern was observed in most normal tissues. Strongest immunoreactivity was observed in alveolar macrophages, adrenal gland and reaction centra cells of tonsil. Squamous epithelia, renal glomeruli and smooth muscle cells were generally negative.
HPA028561
Most of the normal tissues displayed weak to moderate cytoplasmic and occasional nuclear positivity. Strong staining was observed in airway epithlia, breast and bone marrow poetic cells.
HPA028562
Normal tissues showed weak to moderate cytoplasmic staining. Renal tubules showed strong cytoplasmic and membranous staining while purkinje cells exhibited strong cytoplasmic immunoreactivity. Bile duct cells, squamous epithelia, CNS and lymphoid cells were in general weakly stained or negative.
The Human Protein Atlas project is funded
