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RPL39L
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  • RPL39L
PROTEIN SUMMARY SECTION OVERVIEW GENE INFORMATION RNA DATA ANTIBODY DATA
GENERAL INFORMATIONi

General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.

Gene namei

Official gene symbol, which is typically a short form of the gene name, according to HGNC.

RPL39L
Synonyms RPL39L1
Gene descriptioni

Full gene name according to HGNC.

Ribosomal protein L39 like
Protein classi

Assigned HPA protein class(es) for the encoded protein(s).

Ribosomal proteins
Predicted locationi

All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions.

  • Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached.

  • Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s).

The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location.

Intracellular
Protein evidence Evidence at protein level (all genes)
GENE INFORMATIONi

Gene information from Ensembl and Entrez, as well as links to available gene identifiers are displayed here. Information was retrieved from Ensembl if not indicated otherwise.

Chromosome 3
Cytoband q27.3
Chromosome location (bp) 187120948 - 187180908
Number of transcriptsi

Number of protein-coding transcripts from the gene as defined by Ensembl.

3
Ensembl ENSG00000163923 (version 109)
Entrez gene 116832
HGNC HGNC:17094
UniProt Q96EH5 (UniProt - Evidence at protein level)
neXtProt NX_Q96EH5
GeneCards RPL39L
Antibodypedia RPL39L antibodies


PROTEIN FUNCTION
Protein function (UniProt)i

Useful information about the protein provided by UniProt.

Male germ cell-specific component of the ribosome, which is required for the formation of sperm and male fertility. Replaces the RPL39 paralog in the ribosome of male germ cells. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The male germ cell-specific ribosome displays a ribosomal polypeptide exit tunnel of distinct size and charge states compared with the classical ribosome. It is responsible for regulating the biosynthesis and folding of a subset of male germ-cell-specific proteins that are essential for the formation of sperm.... show less
Molecular function (UniProt)i

Keywords assigned by UniProt to proteins due to their particular molecular function.

Ribonucleoprotein, Ribosomal protein
Gene summary (Entrez)i

Useful information about the gene from Entrez

This gene encodes a protein sharing high sequence similarity with ribosomal protein L39. Although the name of this gene has been referred to as 'ribosomal protein L39' in the public databases, its official name is 'ribosomal protein L39-like'. It is not currently known whether the encoded protein is a functional ribosomal protein or whether it has evolved a function that is independent of the ribosome. [provided by RefSeq, Jul 2008]... show less
PROTEIN INFORMATIONi

The protein information section displays alternative protein-coding transcripts (splice variants) encoded by this gene according to the Ensembl database.

The ENSP identifier links to the Ensembl website protein summary, while the ENST identifier links to the Ensembl website transcript summary for the selected splice variant. The data in the UniProt column can be expanded to show links to all matching UniProt identifiers for this protein.

The protein classes assigned to this protein are shown if expanding the data in the protein class column. Parent protein classes are in bold font and subclasses are listed under the parent class.

The Gene Ontology terms assigned to this protein are listed if expanding the Gene ontology column. The length of the protein (amino acid residues according to Ensembl), molecular mass (kDalton), predicted signal peptide (according to a majority of the signal peptide predictors SPOCTOPUS, SignalP 4.0, and Phobius) and the number of predicted transmembrane region(s) (according to MDM) are also reported.
Splice variant SwissProt TrEMBL Protein class Gene ontology Length & mass Signal peptide
(predicted)
Transmembrane regions
(predicted)
RPL39L-201
ENSP00000296277
ENST00000296277
Q96EH5
[Direct mapping] 60S ribosomal protein L39-like
Show all
Ribosomal proteins
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005515 [protein binding]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0007283 [spermatogenesis]
GO:0022625 [cytosolic large ribosomal subunit]
GO:1990904 [ribonucleoprotein complex]
Show all
51 aa
6.3 kDa
No 0
RPL39L-202
ENSP00000389356
ENST00000433055
Q96EH5
[Direct mapping] 60S ribosomal protein L39-like
Show all
Ribosomal proteins
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005515 [protein binding]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0007283 [spermatogenesis]
GO:0022625 [cytosolic large ribosomal subunit]
GO:1990904 [ribonucleoprotein complex]
Show all
51 aa
6.3 kDa
No 0
RPL39L-203
ENSP00000397240
ENST00000455270
Q96EH5
[Direct mapping] 60S ribosomal protein L39-like
Show all
Ribosomal proteins
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Mapped to neXtProt
   neXtProt - Evidence at protein level
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005515 [protein binding]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0007283 [spermatogenesis]
GO:0022625 [cytosolic large ribosomal subunit]
GO:1990904 [ribonucleoprotein complex]
Show all
51 aa
6.3 kDa
No 0

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