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CNPY4
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                                  • CNPY4
                                  PROTEIN SUMMARY SECTION OVERVIEW GENE INFORMATION RNA DATA ANTIBODY DATA
                                  GENERAL INFORMATIONi

                                  General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.

                                  Gene namei

                                  Official gene symbol, which is typically a short form of the gene name, according to HGNC.

                                  CNPY4
                                  Synonyms MGC40499, PRAT4B
                                  Gene descriptioni

                                  Full gene name according to HGNC.

                                  Canopy FGF signaling regulator 4
                                  Predicted locationi

                                  All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions.

                                  • Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached.

                                  • Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s).

                                  The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location.

                                  Intracellular
                                  Protein evidence Evidence at protein level (all genes)
                                  GENE INFORMATIONi

                                  Gene information from Ensembl and Entrez, as well as links to available gene identifiers are displayed here. Information was retrieved from Ensembl if not indicated otherwise.

                                  Chromosome 7
                                  Cytoband q22.1
                                  Chromosome location (bp) 100119634 - 100125508
                                  Number of transcriptsi

                                  Number of protein-coding transcripts from the gene as defined by Ensembl.

                                  2
                                  Ensembl ENSG00000166997 (version 109)
                                  Entrez gene 245812
                                  HGNC HGNC:28631
                                  UniProt Q8N129 (UniProt - Evidence at protein level)
                                  neXtProt NX_Q8N129
                                  GeneCards CNPY4
                                  Antibodypedia CNPY4 antibodies


                                  PROTEIN FUNCTION
                                  Protein function (UniProt)i

                                  Useful information about the protein provided by UniProt.

                                  Plays a role in the regulation of the cell surface expression of TLR4.... show less
                                  Gene summary (Entrez)i

                                  Useful information about the gene from Entrez

                                  Predicted to enable signaling receptor binding activity. Involved in positive regulation of protein localization to plasma membrane. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]... show less
                                  PROTEIN INFORMATIONi

                                  The protein information section displays alternative protein-coding transcripts (splice variants) encoded by this gene according to the Ensembl database.

                                  The ENSP identifier links to the Ensembl website protein summary, while the ENST identifier links to the Ensembl website transcript summary for the selected splice variant. The data in the UniProt column can be expanded to show links to all matching UniProt identifiers for this protein.

                                  The protein classes assigned to this protein are shown if expanding the data in the protein class column. Parent protein classes are in bold font and subclasses are listed under the parent class.

                                  The Gene Ontology terms assigned to this protein are listed if expanding the Gene ontology column. The length of the protein (amino acid residues according to Ensembl), molecular mass (kDalton), predicted signal peptide (according to a majority of the signal peptide predictors SPOCTOPUS, SignalP 4.0, and Phobius) and the number of predicted transmembrane region(s) (according to MDM) are also reported.
                                  Splice variant SwissProt TrEMBL Protein class Gene ontology Length & mass Signal peptide
                                  (predicted)
                                  Transmembrane regions
                                  (predicted)
                                  CNPY4-201
                                  ENSP00000262932
                                  ENST00000262932
                                  Q8N129
                                  [Direct mapping] Protein canopy homolog 4
                                  Show all
                                     MEMSAT3 predicted membrane proteins
                                     Secreted proteins predicted by MDSEC
                                     SignalP predicted secreted proteins
                                     Phobius predicted secreted proteins
                                     SPOCTOPUS predicted secreted proteins
                                  Predicted intracellular proteins
                                  Mapped to neXtProt
                                     neXtProt - Evidence at protein level
                                  Protein evidence (Kim et al 2014)
                                  Protein evidence (Ezkurdia et al 2014)
                                  Show all
                                  GO:0003674 [molecular_function]
                                  GO:0005102 [signaling receptor binding]
                                  GO:0005515 [protein binding]
                                  GO:0005576 [extracellular region]
                                  GO:1903078 [positive regulation of protein localization to plasma membrane]
                                  Show all
                                  248 aa
                                  28.3 kDa
                                  Yes 0
                                  CNPY4-205
                                  ENSP00000488362
                                  ENST00000483756
                                  A0A0J9YXE1
                                  [Direct mapping] Protein canopy homolog 4
                                  Show all
                                  Predicted intracellular proteins
                                     Intracellular proteins predicted by MDM and MDSEC
                                  Protein evidence (Ezkurdia et al 2014)
                                  Show all
                                  36 aa
                                  4 kDa
                                  No 0

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