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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA011088
Most normal tissues showed moderate to strong cytoplasmic immunoreactivity. Glial cells, bile ducts, renal glomeruli and myocytes were mainly negative.
HPA012123
Most normal tissues showed moderate cytoplasmic staining. Endocrine glands, trophoblasts, alveolar macrophages and Purkinje cells of cerebellum displayed strong positivity. The majority of cells in CNS and muscle cells were weakly stained or negative.
CAB037128
Moderate to strong cytoplasmic and membranous positivity was observed in normal tissues. Muscle tissues showed moderate staining. Glial cells were weakly stained.
CAB037288
Most normal tissues displayed moderate to strong cytoplasmic staining. Majority of CNS tissues displayed additional nuclear positivity. Glandular cells in stomach, small intestine, prostate and urothelium showed additional membranous positivity.
The Human Protein Atlas project is funded
