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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
No data
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
42.7
nTPM
HPA Brain:
273.7
nTPM
GTEx:
42.7
nTPM
MIDBRAIN - HPA Brain RNA-seq
Max nTPM
273.7
Sample id
Sample description
nTPM
Cuneiform nucleus nTPM: 167.2
2219
Male, age 76, both hemispheres
245.7
2666
Male, age 74, left hemisphere
227.3
1833
Male, age 53, unknown
186.0
1830
Male, age 51, unknown
176.1
2828
Female, age 72, unknown
175.6
2586
Male, age 75, left hemisphere
156.5
1870
Female, age 42, unknown
138.5
1827
Male, age 72, unknown
131.0
2019
Male, age 18, unknown
119.4
2411
Female, age 72, unknown
116.0
Dorsal raphe nucleus nTPM: 123.9
2047
Male, age 72, unknown
155.4
2750
Male, age 76, both hemispheres
146.3
1828
Male, age 53, unknown
135.2
2016
Female, age 72, unknown
102.2
2298
Female, age 72, unknown
80.5
Inferior colliculus nTPM: 142.9
2849
Male, age 72, unknown
225.6
1890
Male, age 53, unknown
135.6
1848
Female, age 42, unknown
133.0
2097
Female, age 72, unknown
77.5
Median raphe nucleus nTPM: 273.7
2220
Male, age 76, midline
273.7
Periaquaductal grey, anterior nTPM: 117.4
1795
Male, age 51, unknown
128.0
1947
Male, age 18, unknown
117.5
2502
Female, age 75, unknown
106.7
Periaquaductal grey, dorsal nTPM: 149.0
2850
Male, age 76, both hemispheres
218.2
1831
Male, age 72, unknown
144.9
2464
Female, age 72, unknown
134.9
1840
Male, age 53, unknown
98.1
Periaquaductal grey, lateral nTPM: 146.0
2140
Male, age 76, both hemispheres
185.5
2272
Male, age 74, both hemispheres
131.7
2053
Male, age 18, unknown
120.7
Pretectal area nTPM: 130.9
2407
Male, age 75, both hemispheres
170.0
2825
Male, age 18, unknown
153.9
2316
Male, age 76, right hemisphere
141.0
2224
Female, age 72, unknown
138.7
2667
Female, age 75, unknown
138.0
1817
Female, age 42, unknown
126.1
1815
Male, age 53, unknown
125.4
1816
Male, age 51, unknown
124.3
1944
Female, age 72, unknown
120.9
2007
Male, age 72, unknown
111.8
2273
Male, age 74, both hemispheres
89.7
Red nucleus nTPM: 165.7
2588
Male, age 74, left hemisphere
237.5
2823
Male, age 76, right hemisphere
233.7
2584
Male, age 75, left hemisphere
180.4
2769
Male, age 72, unknown
164.1
1865
Male, age 51, unknown
163.9
2227
Male, age 72, unknown
162.0
2785
Male, age 18, unknown
159.4
1904
Male, age 53, unknown
152.3
2725
Female, age 75, unknown
149.8
2503
Female, age 72, unknown
148.9
1954
Female, age 42, unknown
135.4
1821
Female, age 72, unknown
100.8
Substantia nigra nTPM: 133.3
2699
Male, age 18, unknown
220.5
2665
Male, age 74, both hemispheres
168.3
2583
Male, age 75, right hemisphere
158.6
1941
Male, age 53, unknown
150.7
2590
Female, age 75, unknown
114.6
1916
Female, age 42, unknown
110.9
1851
Male, age 51, unknown
108.0
1889
Female, age 72, unknown
106.2
2241
Male, age 72, unknown
100.5
2409
Female, age 72, unknown
94.3
Superior colliculus nTPM: 137.6
2668
Female, age 75, unknown
169.9
2664
Male, age 75, both hemispheres
157.1
2587
Male, age 74, left hemisphere
145.6
1913
Female, age 42, unknown
143.3
2087
Female, age 72, unknown
141.3
1839
Male, age 51, unknown
139.7
1895
Male, age 76, right hemisphere
130.9
1796
Male, age 53, unknown
128.4
1995
Male, age 72, unknown
111.0
2261
Male, age 18, unknown
109.0
Ventral tegmental area nTPM: 140.6
2218
Male, age 76, both hemispheres
179.2
2223
Female, age 72, unknown
178.7
2021
Male, age 53, unknown
150.5
1942
Male, age 51, unknown
137.1
1915
Female, age 42, unknown
110.1
2410
Female, age 72, unknown
87.7
MIDBRAIN - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Average nTPM
42.7
GTEx sample id
Sample description
nTPM
Brain - Substantia nigra Average nTPM: 42.7
Samples: 139
Max nTPM: 121.3
Min nTPM: 10.9
Std nTPM: 18.2
Median nTPM: 38.2
The Human Protein Atlas project is funded
