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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA049405
Most normal tissues showed weak to moderate cytoplasmic positivity. Trophoblastic cells, epididymis displayed strong immunoreactivity. A subset of cells in germinal center cells of lymph node showed strong cytoplasmic staining. Pneumocytes, breast, muscle tissues, soft tissues, islet of Langerhans, Leydig cells, lymphoid tissues, stromal cells in uterus and cervix were in general negative.
CAB025561
Strong cytoplasmic positivity was observed in exocrine pancreas, stomach, trophoblastic cells, epididymis, seminal vesicle and a subset of lymphoid cells. Remaining normal cells displayed weak staining or were negative.