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TMEM50A
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                                  • TMEM50A
                                  BRAIN PONS AND MEDULLA Show tissue menu
                                  AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
                                  MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
                                  Brain proteome
                                  PONS AND MEDULLA - Expression summary
                                  Protein expressioni

                                  On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

                                  Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

                                  If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

                                  No data
                                  RNA expressioni

                                  A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

                                  The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

                                  Scroll down to view mRNA expression data in more detail.
                                  HPA Brain:32.5 nTPM
                                  FANTOM5:90.7 Scaled Tags Per Million
                                  Pig:79.7 nTPM
                                  Mouse:144.2 nTPM
                                  Allen mouse:3.5 Expression energy

                                  PONS AND MEDULLA - Annotated protein expression
                                  Pending normal tissue analysis

                                  PONS AND MEDULLA - HPA Brain RNA-seq
                                  Max nTPM 32.5
                                  Sample id Sample description nTPM
                                  Anterior cochlear nucleus, ventral
                                  nTPM: 24.4
                                  2188 Female, age 91, both hemispheres 27.2
                                  2090 Male, age 80, both hemispheres 24.7
                                  2301 Female, age 85, both hemispheres 24.7
                                  1984 Male, age 76, both hemispheres 21.0
                                  Area postrema
                                  nTPM: 23.7
                                  2306 Male, age 80, both hemispheres 28.1
                                  2799 Male, age 61, both hemispheres 21.8
                                  2054 Male, age 76, both hemispheres 21.2
                                  Dorsal cochlear nucleus
                                  nTPM: 24.8
                                  2378 Male, age 80, both hemispheres 28.1
                                  2187 Female, age 91, both hemispheres 27.0
                                  2802 Male, age 74, right hemisphere 25.9
                                  2370 Male, age 61, both hemispheres 21.8
                                  2058 Male, age 76, both hemispheres 21.1
                                  Dorsal medullary reticular nucleus
                                  nTPM: 23.3
                                  2040 Female, age 85, both hemispheres 27.7
                                  2373 Male, age 61, both hemispheres 23.1
                                  2088 Male, age 76, both hemispheres 19.0
                                  Dorsal motor vagal complex
                                  nTPM: 20.6
                                  2185 Male, age 76, both hemispheres 24.0
                                  2807 Female, age 85, both hemispheres 23.8
                                  2813 Female, age 72, unknown 20.9
                                  2133 Female, age 91, both hemispheres 20.3
                                  2000 Male, age 74, unknown 20.0
                                  2643 Male, age 74, both hemispheres 19.5
                                  2844 Male, age 55, unknown 18.4
                                  2797 Male, age 61, both hemispheres 18.3
                                  Dorsal tegmental nucleus
                                  nTPM: 22.9
                                  2326 Male, age 74, both hemispheres 23.9
                                  2358 Male, age 61, both hemispheres 23.6
                                  2083 Male, age 80, both hemispheres 22.3
                                  1936 Male, age 76, left hemisphere 21.8
                                  Dorsolateral tegmental area
                                  nTPM: 24.1
                                  2337 Male, age 61, both hemispheres 28.7
                                  2751 Female, age 85, both hemispheres 28.3
                                  2654 Male, age 80, both hemispheres 24.5
                                  2360 Male, age 74, both hemispheres 21.1
                                  2141 Male, age 76, both hemispheres 17.8
                                  Gigantocellular reticular nuclei, medullary
                                  nTPM: 26.1
                                  2387 Female, age 91, both hemispheres 29.6
                                  1876 Female, age 85, both hemispheres 29.5
                                  2022 Male, age 76, right hemisphere 27.1
                                  2314 Male, age 61, both hemispheres 25.7
                                  2462 Male, age 74, both hemispheres 22.8
                                  2310 Male, age 80, both hemispheres 21.9
                                  Gigantocellular reticular nuclei, pars
                                  nTPM: 20.7
                                  2706 Male, age 80, both hemispheres 22.2
                                  2330 Male, age 80, both hemispheres 20.7
                                  2168 Male, age 76, both hemispheres 20.6
                                  2084 Female, age 85, both hemispheres 20.4
                                  2336 Male, age 61, both hemispheres 19.8
                                  Inferior olive
                                  nTPM: 26.9
                                  2563 Male, age 74, both hemispheres 29.3
                                  2379 Male, age 80, both hemispheres 27.7
                                  2085 Female, age 85, both hemispheres 26.2
                                  2178 Male, age 61, both hemispheres 26.0
                                  2628 Female, age 91, both hemispheres 25.4
                                  Kolliker-Fuse nucleus
                                  nTPM: 26.9
                                  2315 Male, age 76, right hemisphere 29.1
                                  2793 Female, age 91, left hemisphere 28.5
                                  2163 Male, age 80, both hemispheres 23.0
                                  Lateral lemniscal nuclei
                                  nTPM: 24.1
                                  2036 Male, age 80, both hemispheres 26.0
                                  2320 Female, age 91, left hemisphere 24.6
                                  2453 Male, age 74, right hemisphere 24.4
                                  2169 Male, age 76, both hemispheres 23.1
                                  2746 Female, age 85, left hemisphere 22.3
                                  Lateral medullary reticular nucleus
                                  nTPM: 27.3
                                  2305 Male, age 74, both hemispheres 31.3
                                  2804 Female, age 91, both hemispheres 29.0
                                  2190 Female, age 85, both hemispheres 28.2
                                  2852 Male, age 80, both hemispheres 27.6
                                  2044 Male, age 76, both hemispheres 24.1
                                  2374 Male, age 61, both hemispheres 23.7
                                  Lateral parabrachial nucleus
                                  nTPM: 25.3
                                  2792 Male, age 76, both hemispheres 33.7
                                  2013 Male, age 80, both hemispheres 26.4
                                  2139 Female, age 85, right hemisphere 21.6
                                  2790 Male, age 61, both hemispheres 19.7
                                  Lateral vestibular nucleus
                                  nTPM: 22.5
                                  2311 Male, age 80, both hemispheres 23.8
                                  2184 Male, age 76, both hemispheres 21.1
                                  Locus coeruleus
                                  nTPM: 21.0
                                  2720 Male, age 74, both hemispheres 23.9
                                  2788 Male, age 74, unknown 22.4
                                  2317 Female, age 72, unknown 21.4
                                  2014 Male, age 55, unknown 21.0
                                  2162 Male, age 80, both hemispheres 19.9
                                  2123 Female, age 91, both hemispheres 19.4
                                  1980 Male, age 76, both hemispheres 19.2
                                  Medial olivary nucleus
                                  nTPM: 31.2
                                  1943 Male, age 61, both hemispheres 34.9
                                  1962 Male, age 76, both hemispheres 32.4
                                  2138 Female, age 91, both hemispheres 30.4
                                  2851 Male, age 80, both hemispheres 27.1
                                  Medial parabrachial nucleus
                                  nTPM: 23.3
                                  2170 Female, age 91, both hemispheres 28.7
                                  2854 Male, age 80, both hemispheres 26.0
                                  2463 Female, age 85, right hemisphere 21.8
                                  2786 Male, age 76, both hemispheres 21.2
                                  2156 Male, age 61, both hemispheres 19.0
                                  Medial periolivary nuclei
                                  nTPM: 23.9
                                  2791 Male, age 74, right hemisphere 29.7
                                  2081 Male, age 80, both hemispheres 24.5
                                  2458 Female, age 91, both hemispheres 23.2
                                  2063 Male, age 76, both hemispheres 22.2
                                  2171 Female, age 85, both hemispheres 19.8
                                  Medial vestibular nucleus
                                  nTPM: 24.5
                                  2801 Male, age 74, both hemispheres 29.9
                                  2803 Female, age 91, both hemispheres 29.6
                                  2093 Male, age 80, both hemispheres 23.0
                                  2743 Female, age 85, both hemispheres 22.9
                                  2624 Male, age 61, both hemispheres 22.1
                                  2134 Male, age 76, both hemispheres 19.5
                                  Motor facial nucleus
                                  nTPM: 23.4
                                  2365 Male, age 74, right hemisphere 31.5
                                  2795 Female, age 91, both hemispheres 25.0
                                  2062 Male, age 76, both hemispheres 22.9
                                  2697 Female, age 85, both hemispheres 22.8
                                  2126 Male, age 61, both hemispheres 19.2
                                  2327 Male, age 80, both hemispheres 19.2
                                  Motor hypoglossal nucleus
                                  nTPM: 21.3
                                  2125 Female, age 91, both hemispheres 26.9
                                  2132 Female, age 85, both hemispheres 23.2
                                  2182 Male, age 80, both hemispheres 21.6
                                  2461 Male, age 61, both hemispheres 18.4
                                  2277 Male, age 76, both hemispheres 16.4
                                  Motor trigeminal nucleus
                                  nTPM: 21.6
                                  2560 Male, age 74, both hemispheres 25.1
                                  2321 Female, age 91, both hemispheres 21.9
                                  2309 Male, age 76, both hemispheres 21.8
                                  2079 Male, age 80, both hemispheres 20.3
                                  2335 Male, age 61, both hemispheres 19.0
                                  Nuclei of the trapezoid body
                                  nTPM: 21.7
                                  1983 Male, age 76, both hemispheres 23.8
                                  2368 Female, age 91, both hemispheres 22.8
                                  2166 Male, age 80, both hemispheres 21.3
                                  2159 Male, age 61, both hemispheres 21.2
                                  2735 Female, age 85, both hemispheres 19.6
                                  Nucleus ambiguus
                                  nTPM: 21.5
                                  2071 Male, age 76, both hemispheres 30.0
                                  2096 Female, age 85, both hemispheres 13.0
                                  Nucleus cuneatus
                                  nTPM: 24.4
                                  2380 Male, age 80, both hemispheres 31.6
                                  2808 Female, age 85, both hemispheres 30.5
                                  2381 Male, age 80, both hemispheres 28.1
                                  2564 Male, age 74, both hemispheres 25.8
                                  2376 Male, age 61, both hemispheres 24.2
                                  2131 Male, age 76, both hemispheres 20.4
                                  2100 Male, age 76, both hemispheres 19.9
                                  2805 Female, age 91, both hemispheres 19.9
                                  2562 Male, age 61, both hemispheres 19.2
                                  Nucleus gracilis
                                  nTPM: 27.3
                                  2382 Male, age 80, both hemispheres 29.1
                                  2627 Male, age 74, both hemispheres 28.7
                                  2299 Female, age 85, both hemispheres 24.1
                                  Nucleus raphe magnus
                                  nTPM: 22.1
                                  2455 Male, age 74, both hemispheres 26.0
                                  2051 Male, age 76, both hemispheres 25.2
                                  2459 Female, age 91, both hemispheres 23.6
                                  2328 Male, age 80, both hemispheres 22.0
                                  2160 Male, age 61, both hemispheres 18.6
                                  2172 Female, age 85, both hemispheres 17.0
                                  Nucleus raphe obscurus
                                  nTPM: 31.1
                                  2845 Female, age 85, midline 36.6
                                  2142 Male, age 76, midline 30.6
                                  2800 Male, age 61, midline 26.0
                                  Nucleus raphe pallidus
                                  nTPM: 32.5
                                  1924 Male, age 61, midline 37.7
                                  2145 Male, age 76, midline 35.2
                                  2183 Male, age 80, midline 24.6
                                  Nucleus tractus solitarii
                                  nTPM: 19.3
                                  2144 Female, age 91, right hemisphere 23.2
                                  2191 Female, age 85, both hemispheres 20.2
                                  2656 Male, age 76, both hemispheres 18.9
                                  2307 Male, age 80, both hemispheres 15.0
                                  Paramedian reticular nucleus
                                  nTPM: 23.5
                                  2052 Male, age 76, both hemispheres 30.1
                                  2050 Female, age 85, both hemispheres 23.5
                                  2057 Male, age 80, both hemispheres 20.6
                                  2313 Male, age 61, both hemispheres 19.8
                                  Parvicellular reticular nuclei
                                  nTPM: 22.9
                                  2119 Male, age 80, both hemispheres 24.0
                                  2095 Male, age 76, both hemispheres 23.6
                                  2558 Male, age 74, both hemispheres 21.3
                                  Parvicellular reticular nuclei, medullary
                                  nTPM: 21.8
                                  2189 Female, age 91, both hemispheres 24.6
                                  2181 Male, age 80, left hemisphere 20.6
                                  2091 Female, age 85, both hemispheres 20.3
                                  Pedunculopontine tegmental nucleus
                                  nTPM: 25.4
                                  2338 Male, age 61, both hemispheres 26.9
                                  1921 Female, age 85, both hemispheres 24.9
                                  2334 Male, age 80, both hemispheres 24.3
                                  Peritrigeminal nucleus
                                  nTPM: 25.1
                                  2067 Female, age 85, both hemispheres 25.9
                                  2136 Male, age 76, both hemispheres 25.1
                                  2179 Male, age 61, both hemispheres 24.1
                                  Pontine nuclei
                                  nTPM: 24.1
                                  2454 Male, age 74, left hemisphere 32.6
                                  2319 Female, age 91, both hemispheres 28.9
                                  1863 Male, age 55, unknown 26.2
                                  2109 Female, age 72, unknown 24.5
                                  2727 Male, age 61, right hemisphere 21.2
                                  1968 Male, age 76, left hemisphere 20.2
                                  2115 Male, age 80, left hemisphere 20.2
                                  2787 Female, age 85, both hemispheres 19.0
                                  Pontine raphe nucleus
                                  nTPM: 20.8
                                  2853 Male, age 76, midline 21.7
                                  2122 Female, age 85, midline 20.0
                                  Posteroventral cochlear nucleus
                                  nTPM: 25.0
                                  2341 Male, age 80, both hemispheres 33.0
                                  2135 Female, age 91, both hemispheres 26.5
                                  2070 Male, age 76, both hemispheres 22.7
                                  2371 Male, age 61, both hemispheres 22.2
                                  2752 Female, age 85, both hemispheres 20.4
                                  Prepositus hypoglossal nucleus
                                  nTPM: 23.8
                                  2855 Female, age 85, right hemisphere 28.5
                                  2086 Male, age 80, both hemispheres 19.1
                                  Principal sensory trigeminal nucleus
                                  nTPM: 21.9
                                  2367 Female, age 91, left hemisphere 27.2
                                  2324 Male, age 76, both hemispheres 21.4
                                  2008 Male, age 80, left hemisphere 21.3
                                  2158 Male, age 61, both hemispheres 17.9
                                  Reticular pontine nucleus, caudal
                                  nTPM: 23.7
                                  2457 Female, age 91, both hemispheres 28.0
                                  2559 Male, age 74, both hemispheres 25.6
                                  2092 Male, age 76, both hemispheres 23.7
                                  2332 Male, age 80, right hemisphere 17.5
                                  Reticular pontine nucleus, oral
                                  nTPM: 28.6
                                  2361 Male, age 74, both hemispheres 41.2
                                  2366 Female, age 91, both hemispheres 26.8
                                  1939 Male, age 80, both hemispheres 26.0
                                  2012 Female, age 85, both hemispheres 25.2
                                  2167 Male, age 76, both hemispheres 23.8
                                  Reticulotegmental nucleus
                                  nTPM: 22.1
                                  2322 Female, age 91, both hemispheres 24.6
                                  2452 Male, age 74, both hemispheres 22.7
                                  2333 Male, age 80, both hemispheres 22.0
                                  2325 Male, age 76, both hemispheres 18.9
                                  Spinal trigeminal nucleus, caudal
                                  nTPM: 24.0
                                  2390 Female, age 91, both hemispheres 26.4
                                  2312 Male, age 61, both hemispheres 26.1
                                  2447 Male, age 76, both hemispheres 23.0
                                  2308 Male, age 80, both hemispheres 22.8
                                  2642 Male, age 74, both hemispheres 21.9
                                  Spinal trigeminal nucleus, interpolar
                                  nTPM: 24.3
                                  2386 Female, age 85, both hemispheres 28.0
                                  2033 Male, age 80, both hemispheres 24.5
                                  2389 Female, age 91, both hemispheres 23.6
                                  2066 Male, age 76, right hemisphere 22.9
                                  2625 Male, age 61, both hemispheres 22.4
                                  Spinal trigeminal nucleus, oral
                                  nTPM: 21.9
                                  1978 Male, age 76, both hemispheres 22.9
                                  2164 Male, age 80, both hemispheres 21.8
                                  2737 Female, age 85, both hemispheres 21.1
                                  Spinal vestibular nucleus
                                  nTPM: 23.5
                                  2806 Female, age 85, both hemispheres 27.6
                                  2186 Female, age 91, both hemispheres 23.8
                                  2748 Male, age 76, both hemispheres 23.2
                                  2780 Male, age 80, both hemispheres 22.8
                                  2796 Male, age 61, both hemispheres 21.9
                                  2384 Male, age 74, both hemispheres 21.6
                                  Subcoeruleus area
                                  nTPM: 23.6
                                  2369 Female, age 85, left hemisphere 31.8
                                  1958 Male, age 80, both hemispheres 23.6
                                  2451 Male, age 74, both hemispheres 21.4
                                  2323 Female, age 91, left hemisphere 21.1
                                  2089 Male, age 76, left hemisphere 20.3
                                  Superior olive
                                  nTPM: 25.2
                                  2364 Male, age 74, right hemisphere 34.5
                                  2020 Male, age 76, both hemispheres 26.6
                                  1875 Female, age 85, both hemispheres 22.4
                                  2329 Male, age 80, right hemisphere 21.2
                                  2561 Female, age 91, both hemispheres 21.1
                                  Superior vestibular nucleus
                                  nTPM: 23.9
                                  2383 Male, age 74, both hemispheres 27.0
                                  2015 Male, age 80, both hemispheres 23.4
                                  2061 Male, age 76, both hemispheres 21.3
                                  Ventral medullary reticular nucleus
                                  nTPM: 23.5
                                  2372 Male, age 61, both hemispheres 26.0
                                  2060 Male, age 76, both hemispheres 21.0
                                  Ventral periolivary nuclei
                                  nTPM: 22.4
                                  2023 Male, age 76, both hemispheres 28.2
                                  2165 Male, age 80, both hemispheres 21.4
                                  2794 Female, age 91, left hemisphere 20.9
                                  2130 Female, age 85, both hemispheres 19.0
                                  Ventrolateral medulla, A1-C1 cell groups
                                  nTPM: 26.0
                                  2118 Male, age 80, both hemispheres 26.6
                                  2180 Male, age 61, both hemispheres 26.4
                                  1986 Male, age 76, both hemispheres 26.3
                                  2741 Female, age 85, both hemispheres 26.2
                                  2302 Female, age 91, both hemispheres 24.3
                                  Ventrolateral tegmental area, A5 NE cell group
                                  nTPM: 24.9
                                  2359 Male, age 61, both hemispheres 27.9
                                  2840 Female, age 85, both hemispheres 25.8
                                  2456 Female, age 91, both hemispheres 24.8
                                  1959 Male, age 76, both hemispheres 24.2
                                  2449 Male, age 74, both hemispheres 24.2
                                  2161 Male, age 80, both hemispheres 22.6

                                  PONS AND MEDULLA - FANTOM5 CAGEi

                                  RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

                                  Max Scaled Tags Per Million 90.7
                                  FANTOM5 sample id Sample description Scaled Tags Per Million
                                  Locus coeruleus
                                  Scaled Tags Per Million: 89.5
                                  FF:10165-103B3 76 years, female 101.9
                                  FF:10182-103D2 60 years, female 77.1
                                  Medulla oblongata
                                  Scaled Tags Per Million: 90.7
                                  FF:10174-103C3 60 years, female 101.3
                                  FF:10155-103A2 76 years, female 91.2
                                  FF:10038-101F2 18-64 years, mixed 79.6
                                  Pons
                                  Scaled Tags Per Million: 80.4
                                  FF:10033-101E6 18-54 years, mixed 80.4

                                  PONS AND MEDULLA - Pig RNA-seqi

                                  RNA-seq data obtained from pig brain is reported as nTPM .

                                  Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
                                  Average nTPM 79.7
                                  Pig sample Sample description nTPM
                                  67.574.686.765.8103.60102030405060708090100
                                  67.574.686.765.8103.60102030405060708090100
                                  Medulla oblongata
                                  nTPM: 79.7
                                  Samples: 4

                                  Max nTPM: 103.6
                                  Min nTPM: 65.8
                                  Sample A Female 68.1
                                  Sample B Female 65.8
                                  Sample C Male 81.1
                                  Sample D Male 103.6
                                  69.677.785.760.994.00102030405060708090
                                  69.677.785.760.994.00102030405060708090
                                  Pons
                                  nTPM: 77.6
                                  Samples: 4

                                  Max nTPM: 94.0
                                  Min nTPM: 60.9
                                  Sample A Female 72.5
                                  Sample B Female 60.9
                                  Sample C Male 94.0
                                  Sample D Male 82.9

                                  PONS AND MEDULLA - Mouse RNA-seqi

                                  RNA-seq data obtained from mouse brain is reported as nTPM .

                                  Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
                                  Average nTPM 144.2
                                  Mouse sample Sample description nTPM
                                  136.7142.6150.1134.1157.5020406080100120140
                                  136.7142.6150.1134.1157.5020406080100120140
                                  Pons and medulla
                                  nTPM: 144.2
                                  Samples: 4

                                  Max nTPM: 157.5
                                  Min nTPM: 134.1
                                  Sample A Male 137.6
                                  Sample B Male 134.1
                                  Sample C Female 157.5
                                  Sample D Female 147.6

                                  PONS AND MEDULLA - Allen Mouse ISHi

                                  In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

                                  Max Expression energy 3.5
                                  Allen experiment id Experiment description Expression energy
                                  Medulla oblongata
                                  Expression energy: 3.5
                                  69407505 Antisense, RP_050414_01_G08, Mouse strain C57BL/6J (56 days, male) 3.5
                                  Pons
                                  Expression energy: 2.9
                                  69407505 Antisense, RP_050414_01_G08, Mouse strain C57BL/6J (56 days, male) 2.9

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