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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
No data
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
15.7
nTPM
HPA Brain:
83.9
nTPM
GTEx:
15.7
nTPM
MIDBRAIN - HPA Brain RNA-seq
Max nTPM
83.9
Sample id
Sample description
nTPM
Cuneiform nucleus nTPM: 75.5
2666
Male, age 74, left hemisphere
103.8
2019
Male, age 18, unknown
87.4
1830
Male, age 51, unknown
85.2
2219
Male, age 76, both hemispheres
84.4
1833
Male, age 53, unknown
78.9
2411
Female, age 72, unknown
74.5
1870
Female, age 42, unknown
65.7
1827
Male, age 72, unknown
65.0
2828
Female, age 72, unknown
62.4
2586
Male, age 75, left hemisphere
47.4
Dorsal raphe nucleus nTPM: 70.4
2047
Male, age 72, unknown
90.4
2750
Male, age 76, both hemispheres
77.6
2016
Female, age 72, unknown
72.2
1828
Male, age 53, unknown
64.3
2298
Female, age 72, unknown
47.3
Inferior colliculus nTPM: 71.9
1890
Male, age 53, unknown
81.3
1848
Female, age 42, unknown
72.3
2849
Male, age 72, unknown
67.7
2097
Female, age 72, unknown
66.2
Median raphe nucleus nTPM: 83.9
2220
Male, age 76, midline
83.9
Periaquaductal grey, anterior nTPM: 65.8
1947
Male, age 18, unknown
82.2
2502
Female, age 75, unknown
61.2
1795
Male, age 51, unknown
54.0
Periaquaductal grey, dorsal nTPM: 68.5
2464
Female, age 72, unknown
76.1
2850
Male, age 76, both hemispheres
68.3
1831
Male, age 72, unknown
66.8
1840
Male, age 53, unknown
62.7
Periaquaductal grey, lateral nTPM: 70.1
2140
Male, age 76, both hemispheres
79.4
2053
Male, age 18, unknown
70.3
2272
Male, age 74, both hemispheres
60.7
Pretectal area nTPM: 68.2
2316
Male, age 76, right hemisphere
96.2
1944
Female, age 72, unknown
80.3
2407
Male, age 75, both hemispheres
71.8
2007
Male, age 72, unknown
68.9
2224
Female, age 72, unknown
68.6
2667
Female, age 75, unknown
66.3
1816
Male, age 51, unknown
63.5
1815
Male, age 53, unknown
63.0
2825
Male, age 18, unknown
59.5
1817
Female, age 42, unknown
57.1
2273
Male, age 74, both hemispheres
54.2
Red nucleus nTPM: 77.5
2588
Male, age 74, left hemisphere
106.3
2823
Male, age 76, right hemisphere
91.3
1904
Male, age 53, unknown
88.0
1865
Male, age 51, unknown
87.2
2584
Male, age 75, left hemisphere
82.7
2227
Male, age 72, unknown
74.7
2769
Male, age 72, unknown
73.7
1954
Female, age 42, unknown
72.5
2785
Male, age 18, unknown
68.9
2725
Female, age 75, unknown
63.0
2503
Female, age 72, unknown
61.2
1821
Female, age 72, unknown
60.4
Substantia nigra nTPM: 74.1
2409
Female, age 72, unknown
97.1
2241
Male, age 72, unknown
82.2
1941
Male, age 53, unknown
80.7
2583
Male, age 75, right hemisphere
80.7
2665
Male, age 74, both hemispheres
75.4
1889
Female, age 72, unknown
70.7
2590
Female, age 75, unknown
66.9
1851
Male, age 51, unknown
65.7
2699
Male, age 18, unknown
60.9
1916
Female, age 42, unknown
60.5
Superior colliculus nTPM: 68.7
2668
Female, age 75, unknown
96.3
2087
Female, age 72, unknown
81.1
1913
Female, age 42, unknown
77.1
1895
Male, age 76, right hemisphere
73.0
2261
Male, age 18, unknown
67.3
2587
Male, age 74, left hemisphere
66.2
1839
Male, age 51, unknown
64.0
1995
Male, age 72, unknown
58.3
2664
Male, age 75, both hemispheres
54.3
1796
Male, age 53, unknown
49.1
Ventral tegmental area nTPM: 71.1
1942
Male, age 51, unknown
80.1
2223
Female, age 72, unknown
79.3
2021
Male, age 53, unknown
78.3
2410
Female, age 72, unknown
69.6
2218
Male, age 76, both hemispheres
65.5
1915
Female, age 42, unknown
53.8
MIDBRAIN - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Average nTPM
15.7
GTEx sample id
Sample description
nTPM
Brain - Substantia nigra Average nTPM: 15.7
Samples: 139
Max nTPM: 38.3
Min nTPM: 5.2
Std nTPM: 6.2
Median nTPM: 15.1
The Human Protein Atlas project is funded
