CEREBRAL CORTEX - Expression summary
Protein expression
Cerebral cortexi
h
m
l
n
Endothelial cells: Medium
Glial cells: Not detected
Neuronal cells: Medium
Neuropil: Medium
RNA expressioni
Consensus:15.8 nTPM
HPA:11.2 nTPM
HPA Brain:30.8 nTPM
HPA PFC Brain:12.1 nTPM
GTEx:15.8 nTPM
FANTOM5:22.6 Scaled Tags Per Million
Pig:40.4 nTPM
Mouse:44.4 nTPM
Allen mouse:18.8 Expression energy

CEREBRAL CORTEX - Antibody stainingi
Antibody HPA041314
Endothelial cells Medium
Glial cells Not detected
Neuronal cells Medium
Neuropil Medium



CEREBRAL CORTEX - HPA RNA-seqi
Average nTPM 11.2
N/A
Male, age 5
Cerebral cortex sample 48
nTPM: 12.7
overview
Female, age 40
Cerebral cortex sample 105
nTPM: 9.2
Cell types%
Neuronal cells:
35

Glial cells and endothelial cells:
65
overview
Male, age 70
Cerebral cortex sample 106
nTPM: 11.8
Cell types%
Neuronal cells:
35

Glial cells and endothelial cells:
65

CEREBRAL CORTEX - HPA Brain RNA-seq
Max nTPM 30.8
Sample id Sample description nTPM
Angular gyrus
nTPM: 22.9
2103 Male, age 75, left hemisphere 26.9
1790 Male, age 76, right hemisphere 25.5
2722 Male, age 61, left hemisphere 25.3
2602 Female, age 94, right hemisphere 23.4
2265 Female, age 91, left hemisphere 23.0
1866 Male, age 76, both hemispheres 21.2
2260 Female, age 72, left hemisphere 20.1
2221 Female, age 67, right hemisphere 17.6
Anterior cingulate cortex, supragenual-dorsal
nTPM: 20.4
2478 Female, age 67, right hemisphere 23.6
2547 Male, age 74, left hemisphere 22.3
2342 Female, age 94, right hemisphere 19.1
1896 Female, age 85, right hemisphere 18.9
2472 Male, age 75, left hemisphere 18.2
Anterior cingulate cortex, supragenual-ventral
nTPM: 26.0
2479 Female, age 67, right hemisphere 37.2
1755 Female, age 94, right hemisphere 24.3
1950 Female, age 85, right hemisphere 24.2
1761 Male, age 74, left hemisphere 22.7
2538 Male, age 75, left hemisphere 21.5
Anterior insular cortex, dorsal
nTPM: 22.6
2670 Male, age 75, left hemisphere 28.5
2235 Female, age 91, right hemisphere 23.8
2506 Female, age 94, right hemisphere 21.6
2001 Male, age 76, right hemisphere 16.5
Anterior insular cortex, ventral
nTPM: 22.7
2596 Male, age 75, left hemisphere 35.3
2262 Female, age 67, right hemisphere 21.6
1852 Male, age 76, left hemisphere 20.1
1925 Female, age 91, left hemisphere 19.8
2757 Male, age 61, right hemisphere 19.7
2507 Female, age 94, left hemisphere 19.5
Area parastriata, inferior
nTPM: 27.6
2509 Female, age 94, left hemisphere 37.4
2234 Male, age 75, left hemisphere 35.3
1789 Male, age 76, right hemisphere 29.1
1758 Female, age 72, right hemisphere 25.9
1760 Female, age 67, left hemisphere 21.8
2268 Male, age 61, right hemisphere 21.8
2421 Female, age 91, left hemisphere 21.6
Area parastriata, parietal
nTPM: 24.5
2233 Male, age 61, right hemisphere 28.6
2236 Female, age 91, left hemisphere 28.4
1785 Male, age 76, right hemisphere 23.4
2420 Male, age 75, left hemisphere 22.8
2680 Female, age 94, right hemisphere 19.5
Area parastriata, superior
nTPM: 28.1
2881 Male, age 76, left hemisphere 35.1
2604 Female, age 94, right hemisphere 34.3
2435 Male, age 61, left hemisphere 29.2
2684 Female, age 67, left hemisphere 25.1
1773 Female, age 91, left hemisphere 24.4
2419 Male, age 75, right hemisphere 20.9
Area parastriata, temporal
nTPM: 22.7
2267 Male, age 61, right hemisphere 26.4
2471 Male, age 75, left hemisphere 24.4
1804 Male, age 76, right hemisphere 23.5
2681 Female, age 94, right hemisphere 20.9
2424 Female, age 67, left hemisphere 18.3
Area striata
nTPM: 22.7
1884 Male, age 76, left hemisphere 39.3
2417 Male, age 61, right hemisphere 21.5
2002 Female, age 91, right hemisphere 20.3
1753 Female, age 72, right hemisphere 19.7
2679 Female, age 94, right hemisphere 18.1
2427 Female, age 91, left hemisphere 17.7
Claustrum
nTPM: 30.7
2292 Female, age 85, both hemispheres 38.3
1956 Male, age 74, unknown 35.5
2568 Male, age 61, both hemispheres 32.8
2196 Female, age 79, unknown 31.5
2645 Female, age 72, unknown 30.8
2198 Male, age 80, both hemispheres 30.6
2491 Male, age 75, both hemispheres 28.6
2284 Female, age 91, both hemispheres 26.9
2392 Female, age 94, both hemispheres 21.5
Frontal eye field
nTPM: 23.8
2147 Male, age 61, left hemisphere 26.4
2761 Female, age 94, left hemisphere 24.8
2441 Male, age 75, left hemisphere 23.3
2543 Male, age 74, left hemisphere 20.7
Frontal operculum
nTPM: 22.7
2030 Male, age 61, right hemisphere 27.7
2781 Female, age 85, right hemisphere 24.4
2348 Male, age 75, left hemisphere 16.0
Fusiform gyrus
nTPM: 26.7
2431 Male, age 75, right hemisphere 36.9
2784 Female, age 85, left hemisphere 30.9
1807 Male, age 76, left hemisphere 28.5
2617 Female, age 94, left hemisphere 24.2
2433 Female, age 72, left hemisphere 22.3
2074 Female, age 91, left hemisphere 22.0
2112 Male, age 80, both hemispheres 21.8
Inferior frontal gyrus, opercular
nTPM: 24.1
2873 Female, age 85, left hemisphere 27.5
2865 Male, age 61, left hemisphere 27.0
2875 Female, age 67, left hemisphere 26.3
2872 Female, age 94, right hemisphere 24.6
2867 Male, age 75, left hemisphere 24.4
2869 Male, age 74, left hemisphere 24.2
2866 Male, age 61, right hemisphere 23.1
2868 Male, age 75, right hemisphere 23.0
2871 Female, age 94, left hemisphere 22.1
2874 Female, age 85, right hemisphere 18.4
Inferior parietal lobule
nTPM: 23.7
2876 Male, age 76, right hemisphere 33.4
2606 Female, age 67, right hemisphere 25.7
2418 Male, age 75, left hemisphere 18.2
2599 Female, age 94, left hemisphere 17.5
Inferior temporal gyrus
nTPM: 22.8
2689 Female, age 94, right hemisphere 25.6
1808 Male, age 76, left hemisphere 25.3
2430 Male, age 75, right hemisphere 23.7
1965 Female, age 91, left hemisphere 21.2
1970 Female, age 85, right hemisphere 21.1
1880 Male, age 80, right hemisphere 20.1
Intraparietal deep sulcus
nTPM: 25.6
2600 Female, age 94, right hemisphere 30.7
2102 Female, age 91, left hemisphere 27.9
2230 Male, age 61, right hemisphere 26.9
2607 Female, age 67, right hemisphere 26.5
2798 Male, age 76, left hemisphere 21.3
2669 Male, age 75, left hemisphere 20.4
Lingual gyrus
nTPM: 25.2
1893 Male, age 76, left hemisphere 27.0
2618 Female, age 94, left hemisphere 27.0
2073 Female, age 85, left hemisphere 25.8
2688 Male, age 75, right hemisphere 23.1
2838 Male, age 80, right hemisphere 23.0
Middle cingulate cortex
nTPM: 24.2
2640 Female, age 94, right hemisphere 29.2
2539 Male, age 75, left hemisphere 28.1
2633 Male, age 74, left hemisphere 23.5
2357 Female, age 67, right hemisphere 21.6
2028 Female, age 85, left hemisphere 18.7
Middle temporal gyrus
nTPM: 22.7
1799 Male, age 76, left hemisphere 25.3
1819 Male, age 80, right hemisphere 24.3
2616 Female, age 94, left hemisphere 23.7
2611 Male, age 75, right hemisphere 22.4
2034 Female, age 91, right hemisphere 17.6
Occipital cortex
nTPM: 20.5
2677 Female, age 67, right hemisphere 24.5
2608 Female, age 67, both hemispheres 21.3
2470 Male, age 75, right hemisphere 20.1
2426 Male, age 75, midline 18.9
1842 Male, age 76, right hemisphere 17.7
Olfactory area
nTPM: 21.8
1805 Female, age 85, right hemisphere 24.2
2352 Female, age 94, right hemisphere 24.2
2542 Male, age 74, left hemisphere 23.8
2440 Male, age 75, left hemisphere 22.0
2756 Female, age 67, right hemisphere 18.6
2222 Female, age 67, right hemisphere 18.2
Olfactory tubercle
nTPM: 20.6
2856 Male, age 75, right hemisphere 22.3
2487 Female, age 94, left hemisphere 21.9
1846 Male, age 80, right hemisphere 20.9
1998 Female, age 91, both hemispheres 17.1
Orbitofrontal gyrus, anterior
nTPM: 30.8
2862 Female, age 85, left hemisphere 33.1
2863 Female, age 85, right hemisphere 31.7
2864 Female, age 67, left hemisphere 27.6
Paracentral lobule, anterior
nTPM: 23.6
1776 Female, age 85, right hemisphere 28.7
2474 Male, age 74, left hemisphere 23.3
1754 Male, age 75, left hemisphere 23.1
2340 Female, age 67, right hemisphere 23.1
2638 Female, age 94, right hemisphere 22.2
1926 Male, age 61, left hemisphere 21.2
Paracentral lobule, posterior
nTPM: 27.4
1764 Male, age 74, right hemisphere 28.5
2446 Male, age 75, left hemisphere 28.3
2345 Male, age 61, left hemisphere 27.5
2551 Female, age 94, right hemisphere 26.5
1775 Female, age 85, right hemisphere 26.1
Parietal operculum
nTPM: 20.5
1763 Male, age 74, left hemisphere 22.6
2719 Male, age 75, left hemisphere 21.5
2356 Female, age 67, right hemisphere 19.0
2552 Female, age 94, right hemisphere 18.8
Parieto-insular cortex
nTPM: 22.1
2831 Male, age 76, right hemisphere 24.0
2671 Male, age 75, left hemisphere 22.5
2232 Male, age 61, right hemisphere 21.9
2508 Female, age 94, right hemisphere 21.5
1976 Female, age 91, right hemisphere 20.6
Parieto-occipital transitional area
nTPM: 23.3
2683 Female, age 67, left hemisphere 30.9
2270 Male, age 61, right hemisphere 24.6
1784 Male, age 76, right hemisphere 21.0
2674 Female, age 94, right hemisphere 21.0
2468 Male, age 75, left hemisphere 19.2
Piriform cortex
nTPM: 27.3
2153 Female, age 85, left hemisphere 31.2
2347 Male, age 75, right hemisphere 23.3
Postcentral gyrus
nTPM: 23.6
2533 Male, age 75, right hemisphere 23.6
Postcentral gyrus, dorsal
nTPM: 25.1
2339 Female, age 67, right hemisphere 32.5
2477 Female, age 94, right hemisphere 26.5
2350 Male, age 75, left hemisphere 25.4
2151 Male, age 61, left hemisphere 24.1
2544 Male, age 74, left hemisphere 22.5
1836 Female, age 85, right hemisphere 19.5
Postcentral gyrus, middle
nTPM: 21.1
2545 Male, age 74, left hemisphere 26.7
2444 Male, age 75, left hemisphere 21.1
2248 Male, age 61, left hemisphere 20.4
2146 Female, age 67, right hemisphere 19.3
1897 Female, age 85, right hemisphere 17.9
Postcentral gyrus, ventral
nTPM: 24.7
2836 Female, age 94, right hemisphere 28.1
2024 Female, age 85, right hemisphere 23.5
2445 Male, age 75, left hemisphere 22.6
Posterior cingulate cortex
nTPM: 21.9
2473 Male, age 75, left hemisphere 26.0
1759 Male, age 74, right hemisphere 21.4
2553 Female, age 94, right hemisphere 18.4
Posterior cingulate cortex, dorsal
nTPM: 27.6
2343 Male, age 61, left hemisphere 35.9
2556 Female, age 67, right hemisphere 31.7
2634 Male, age 74, left hemisphere 25.9
2076 Female, age 85, right hemisphere 25.6
2540 Male, age 75, right hemisphere 24.0
2641 Female, age 94, right hemisphere 22.3
Posterior cingulate cortex, ventral
nTPM: 21.6
2541 Male, age 75, right hemisphere 28.5
2448 Female, age 67, right hemisphere 22.4
2346 Male, age 61, left hemisphere 20.9
1762 Female, age 94, right hemisphere 19.6
1994 Female, age 85, right hemisphere 19.6
2635 Male, age 74, left hemisphere 18.4
Posterior insular cortex
nTPM: 22.2
2511 Female, age 67, right hemisphere 24.2
2603 Female, age 94, left hemisphere 23.3
2832 Female, age 91, right hemisphere 22.0
2231 Male, age 61, left hemisphere 21.6
2597 Male, age 75, left hemisphere 21.5
1823 Male, age 76, right hemisphere 20.6
Precentral gyrus
nTPM: 25.7
2557 Male, age 75, right hemisphere 25.7
Precentral gyrus, dorsal
nTPM: 23.7
1756 Male, age 74, left hemisphere 27.7
2442 Male, age 75, left hemisphere 27.4
2476 Female, age 94, right hemisphere 23.0
2354 Female, age 67, right hemisphere 16.7
Precentral gyrus, middle
nTPM: 20.8
2443 Male, age 75, left hemisphere 23.7
2475 Male, age 74, right hemisphere 21.4
2549 Female, age 94, right hemisphere 21.2
1909 Male, age 61, left hemisphere 20.3
1969 Female, age 67, right hemisphere 17.4
Precentral gyrus, ventral
nTPM: 22.9
2550 Female, age 94, right hemisphere 25.3
2630 Male, age 75, left hemisphere 23.5
2662 Female, age 67, right hemisphere 22.6
2678 Male, age 74, left hemisphere 20.3
Precuneus
nTPM: 23.8
2510 Female, age 67, right hemisphere 26.5
1780 Female, age 91, right hemisphere 26.1
2594 Male, age 61, left hemisphere 22.9
2467 Male, age 75, right hemisphere 22.8
1782 Male, age 76, right hemisphere 22.6
2673 Female, age 94, right hemisphere 21.6
Premotor cortex, dorsal
nTPM: 25.1
2554 Female, age 67, right hemisphere 37.2
2631 Male, age 74, left hemisphere 24.4
2536 Male, age 75, left hemisphere 23.2
1878 Female, age 85, right hemisphere 20.6
2027 Male, age 61, left hemisphere 19.9
Premotor cortex, ventral
nTPM: 23.2
1757 Male, age 74, left hemisphere 28.9
1779 Male, age 61, left hemisphere 25.2
1777 Female, age 67, left hemisphere 23.0
2349 Male, age 75, left hemisphere 22.6
2637 Female, age 94, right hemisphere 21.3
1881 Female, age 85, right hemisphere 18.4
Retrosplenial cortex
nTPM: 24.6
1951 Male, age 61, right hemisphere 31.8
2675 Female, age 94, left hemisphere 21.0
1914 Male, age 76, right hemisphere 20.9
Subcentral gyrus, S2
nTPM: 25.1
2555 Female, age 67, right hemisphere 31.8
2072 Male, age 61, left hemisphere 25.9
2839 Female, age 94, right hemisphere 25.1
2762 Male, age 74, left hemisphere 24.9
2351 Male, age 75, left hemisphere 22.2
1964 Female, age 85, right hemisphere 20.5
Superior parietal lobule
nTPM: 23.2
1800 Male, age 76, right hemisphere 25.1
2605 Female, age 67, right hemisphere 23.9
2229 Male, age 61, right hemisphere 23.5
2672 Female, age 94, right hemisphere 23.2
1992 Female, age 91, right hemisphere 20.1
Superior temporal gyrus
nTPM: 21.2
1843 Male, age 76, left hemisphere 23.2
2615 Female, age 94, left hemisphere 22.7
2687 Male, age 75, right hemisphere 22.4
1844 Female, age 91, left hemisphere 19.4
2025 Male, age 80, right hemisphere 18.3
Supplementary motor cortex
nTPM: 22.9
2632 Male, age 74, left hemisphere 29.2
2548 Female, age 94, right hemisphere 22.5
2537 Male, age 75, left hemisphere 21.2
1993 Male, age 61, left hemisphere 18.7
Supramarginal gyrus
nTPM: 22.0
2415 Male, age 61, left hemisphere 24.3
2513 Female, age 72, left hemisphere 22.6
1991 Female, age 91, right hemisphere 22.1
1798 Male, age 76, right hemisphere 20.6
2601 Female, age 94, left hemisphere 20.4
Temporal pole
nTPM: 23.9
2612 Female, age 94, left hemisphere 25.1
1832 Female, age 91, left hemisphere 25.0
2518 Male, age 75, right hemisphere 24.4
1853 Female, age 85, right hemisphere 23.8
1826 Male, age 76, right hemisphere 21.1
Temporo-insular cortex, parainsular gyrus
nTPM: 23.0
2264 Female, age 91, right hemisphere 24.0
2676 Female, age 94, right hemisphere 23.7
2416 Male, age 61, right hemisphere 23.5
2598 Male, age 75, left hemisphere 22.7
1802 Male, age 76, left hemisphere 22.5
2512 Female, age 67, right hemisphere 21.8
Temporo-occipital transitional zone
nTPM: 24.2
1900 Male, age 76, left hemisphere 25.6
1793 Male, age 80, right hemisphere 25.2
2251 Female, age 85, right hemisphere 21.7
Transversal temporal gyrus, anterior
nTPM: 22.9
1809 Male, age 76, right hemisphere 24.7
2522 Female, age 94, left hemisphere 22.9
2610 Male, age 75, right hemisphere 22.8
1910 Male, age 80, right hemisphere 22.2
1888 Female, age 91, left hemisphere 21.8
Transversal temporal gyrus, posterior
nTPM: 23.6
2520 Male, age 75, right hemisphere 27.3
1967 Female, age 91, right hemisphere 24.0
2614 Female, age 94, left hemisphere 23.9
2833 Male, age 80, right hemisphere 22.2
1922 Male, age 76, left hemisphere 20.5

CEREBRAL CORTEX - HPA PFC Brain RNA-seq
Max nTPM 12.1
Sample id Sample description nTPM
Anterior cingulate gyrus, pregenual-dorsal
nTPM: 11.6
1514 Male, age 74, right hemisphere 15.5
1510 Male, age 61, left hemisphere 13.4
1511 Male, age 61, right hemisphere 12.5
1518 Female, age 67, right hemisphere 11.3
1513 Male, age 74, left hemisphere 11.2
1516 Female, age 85, left hemisphere 11.1
1515 Female, age 94, right hemisphere 10.5
1512 Male, age 75, left hemisphere 9.8
1517 Female, age 67, left hemisphere 9.0
Anterior cingulate gyrus, pregenual-ventral
nTPM: 11.3
1521 Male, age 74, left hemisphere 14.1
1519 Male, age 61, left hemisphere 13.0
1522 Male, age 74, right hemisphere 12.3
1523 Female, age 67, left hemisphere 9.5
1520 Male, age 75, right hemisphere 7.3
Anterior cingulate gyrus, subgenual
nTPM: 11.1
1527 Male, age 74, left hemisphere 15.2
1524 Male, age 61, left hemisphere 13.8
1525 Male, age 75, left hemisphere 10.8
1530 Female, age 67, right hemisphere 10.7
1529 Female, age 85, left hemisphere 10.0
1526 Male, age 75, right hemisphere 9.0
1528 Male, age 74, right hemisphere 8.1
Dorsolateral prefrontal cortex
nTPM: 9.1
1448 Female, age 94, right hemisphere 10.2
1447 Female, age 94, left hemisphere 9.7
1449 Female, age 85, right hemisphere 9.3
1445 Male, age 75, right hemisphere 9.0
1450 Female, age 67, right hemisphere 8.9
1446 Male, age 74, right hemisphere 8.7
1444 Male, age 75, left hemisphere 7.9
Dorsomedial prefrontal cortex
nTPM: 9.7
1443 Female, age 67, right hemisphere 14.6
1442 Male, age 75, right hemisphere 10.0
1439 Male, age 61, left hemisphere 9.2
1440 Male, age 61, right hemisphere 8.4
1441 Male, age 75, left hemisphere 6.2
Frontal cortex
nTPM: 8.1
1572 Male, age 61, left hemisphere 11.3
1575 Male, age 75, right hemisphere 10.1
1573 Male, age 61, right hemisphere 10.0
1574 Male, age 75, left hemisphere 9.0
1583 Female, age 67, right hemisphere 8.4
1579 Female, age 94, right hemisphere 7.9
1576 Male, age 74, left hemisphere 7.8
1577 Male, age 74, right hemisphere 7.1
1580 Female, age 85, left hemisphere 7.0
1578 Female, age 94, left hemisphere 6.5
1581 Female, age 85, right hemisphere 6.3
1582 Female, age 67, left hemisphere 6.1
Frontomarginal cortex
nTPM: 8.8
1469 Female, age 94, left hemisphere 11.5
1472 Female, age 67, left hemisphere 11.5
1470 Female, age 94, right hemisphere 10.1
1468 Male, age 74, left hemisphere 9.8
1473 Female, age 67, right hemisphere 9.3
1465 Male, age 61, left hemisphere 8.8
1466 Male, age 61, right hemisphere 8.1
1467 Male, age 75, right hemisphere 6.2
1471 Female, age 85, left hemisphere 3.8
Frontopolar cortex
nTPM: 8.1
1464 Female, age 67, right hemisphere 12.0
1458 Male, age 61, left hemisphere 8.6
1462 Female, age 94, left hemisphere 8.4
1459 Male, age 61, right hemisphere 7.4
1460 Male, age 75, left hemisphere 7.1
1463 Female, age 67, left hemisphere 6.8
1461 Male, age 75, right hemisphere 6.4
Gyrus rectus
nTPM: 7.2
1478 Female, age 94, left hemisphere 8.8
1479 Female, age 94, right hemisphere 8.6
1477 Male, age 75, right hemisphere 7.6
1476 Male, age 75, left hemisphere 7.1
1475 Male, age 61, right hemisphere 6.9
1480 Female, age 85, left hemisphere 6.8
1474 Male, age 61, left hemisphere 6.4
1481 Female, age 67, left hemisphere 5.5
Inferior frontal gyrus, orbital
nTPM: 11.6
1505 Male, age 74, right hemisphere 14.6
1506 Female, age 94, left hemisphere 14.5
1509 Female, age 67, right hemisphere 13.5
1500 Male, age 61, left hemisphere 12.3
1503 Male, age 75, right hemisphere 11.8
1502 Male, age 75, left hemisphere 11.5
1504 Male, age 74, left hemisphere 10.6
1507 Female, age 85, left hemisphere 9.4
1508 Female, age 85, right hemisphere 9.0
1501 Male, age 61, right hemisphere 8.6
Inferior frontal gyrus, triangular
nTPM: 11.7
1544 Male, age 75, right hemisphere 15.3
1546 Female, age 94, right hemisphere 12.9
1545 Male, age 74, right hemisphere 12.1
1547 Female, age 85, left hemisphere 12.0
1542 Male, age 61, left hemisphere 11.7
1543 Male, age 61, right hemisphere 11.2
1549 Female, age 67, left hemisphere 9.3
1548 Female, age 85, right hemisphere 8.7
Orbitofrontal gyrus, lateral
nTPM: 10.7
1499 Female, age 67, right hemisphere 12.8
1494 Male, age 75, left hemisphere 11.4
1495 Female, age 94, left hemisphere 11.1
1493 Male, age 61, right hemisphere 10.6
1496 Female, age 94, right hemisphere 10.3
1497 Female, age 85, left hemisphere 9.4
1498 Female, age 85, right hemisphere 9.3
Orbitofrontal gyrus, medial
nTPM: 7.2
1491 Female, age 67, left hemisphere 11.2
1485 Male, age 74, left hemisphere 8.6
1482 Male, age 61, left hemisphere 8.4
1487 Female, age 94, left hemisphere 7.7
1489 Female, age 85, left hemisphere 7.2
1490 Female, age 85, right hemisphere 6.9
1483 Male, age 75, left hemisphere 6.3
1484 Male, age 75, right hemisphere 6.3
1488 Female, age 94, right hemisphere 6.1
1486 Male, age 74, right hemisphere 5.4
1492 Female, age 67, right hemisphere 5.3
Orbitofrontal gyrus, posterior
nTPM: 12.1
1535 Male, age 74, left hemisphere 16.1
1534 Male, age 75, right hemisphere 14.3
1536 Female, age 94, left hemisphere 13.2
1537 Female, age 94, right hemisphere 13.1
1533 Male, age 75, left hemisphere 12.5
1540 Female, age 67, left hemisphere 11.5
1531 Male, age 61, left hemisphere 11.2
1532 Male, age 61, right hemisphere 11.2
1539 Female, age 85, right hemisphere 10.3
1541 Female, age 67, right hemisphere 10.0
1538 Female, age 85, left hemisphere 9.1
Subcallosal gyrus
nTPM: 7.4
1560 Female, age 67, left hemisphere 9.4
1551 Male, age 61, right hemisphere 9.2
1552 Male, age 75, left hemisphere 9.2
1555 Male, age 74, right hemisphere 7.9
1557 Female, age 94, right hemisphere 7.8
1550 Male, age 61, left hemisphere 7.1
1558 Female, age 85, left hemisphere 7.1
1559 Female, age 85, right hemisphere 6.8
1561 Female, age 67, right hemisphere 6.6
1553 Male, age 75, right hemisphere 6.2
1554 Male, age 74, left hemisphere 6.1
1556 Female, age 94, left hemisphere 5.3
Superior frontal gyrus
nTPM: 8.8
1566 Male, age 74, right hemisphere 12.1
1567 Female, age 94, left hemisphere 11.5
1565 Male, age 75, right hemisphere 10.2
1563 Male, age 61, right hemisphere 10.1
1562 Male, age 61, left hemisphere 9.1
1564 Male, age 75, left hemisphere 8.7
1568 Female, age 94, right hemisphere 7.8
1570 Female, age 85, right hemisphere 7.7
1569 Female, age 85, left hemisphere 5.5
1571 Female, age 67, right hemisphere 5.4
Temporal cortex
nTPM: 8.6
1595 Female, age 94, right hemisphere 13.3
1594 Female, age 94, left hemisphere 9.5
1591 Male, age 75, right hemisphere 8.0
1596 Female, age 85, right hemisphere 7.9
1592 Male, age 74, left hemisphere 7.6
1590 Male, age 61, right hemisphere 7.5
1593 Male, age 74, right hemisphere 6.5
Ventrolateral prefrontal cortex
nTPM: 8.5
1454 Female, age 94, left hemisphere 11.9
1455 Female, age 85, right hemisphere 9.3
1456 Female, age 67, left hemisphere 9.1
1453 Male, age 74, right hemisphere 8.1
1457 Female, age 67, right hemisphere 7.9
1451 Male, age 75, right hemisphere 7.5
1452 Male, age 74, left hemisphere 6.1
Ventromedial prefrontal cortex
nTPM: 8.4
1435 Female, age 94, right hemisphere 13.3
1432 Male, age 61, left hemisphere 9.4
1433 Male, age 61, right hemisphere 9.4
1438 Female, age 67, left hemisphere 7.9
1436 Female, age 85, left hemisphere 6.7
1437 Female, age 85, right hemisphere 6.1
1434 Male, age 75, right hemisphere 5.7

CEREBRAL CORTEX - GTEx RNA-seqi
Average nTPM 15.8
GTEx sample id Sample description nTPM
Brain - Anterior cingulate cortex (BA24)
Average nTPM: 15.7
Samples: 176

Max nTPM: 27.0
Min nTPM: 7.4
Std nTPM: 2.8
Median nTPM: 15.6
GTEX-1EH9U-0011-R3b-SM-CL534 60-69 years, male 27.0
GTEX-N7MT-0011-R3a-SM-2I3GC 60-69 years, female 26.0
GTEX-14BMV-0011-R3a-SM-5ZZU7 50-59 years, male 24.4
GTEX-13IVO-0011-R3b-SM-5IJBJ 70-79 years, male 23.2
GTEX-13OW5-0011-R3a-SM-5L3I5 60-69 years, male 22.5
GTEX-14PJM-0011-R3b-SM-5ZZV9 50-59 years, female 22.5
GTEX-13NYS-0011-R3b-SM-5MR41 60-69 years, male 21.9
GTEX-1F52S-0011-R3a-SM-CKZNI 60-69 years, female 21.7
GTEX-13CIG-0011-R3b-SM-5K7XF 50-59 years, male 21.5
GTEX-ZE9C-0011-R3a-SM-4WKGT 60-69 years, male 20.3
GTEX-139T8-0011-R3b-SM-5HL4R 60-69 years, male 19.6
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Brain - Cortex
Average nTPM: 15.8
Samples: 255

Max nTPM: 27.4
Min nTPM: 6.8
Std nTPM: 2.8
Median nTPM: 16.0
GTEX-13G51-3026-SM-5IJB8 60-69 years, male 27.4
GTEX-1F7RK-1826-SM-7RHI4 20-29 years, female 24.5
GTEX-1QP6S-2926-SM-DTXF8 40-49 years, male 24.1
GTEX-11GS4-3126-SM-5A5LH 60-69 years, male 23.4
GTEX-12ZZY-3026-SM-5GCOU 60-69 years, male 22.3
GTEX-1HFI6-3026-SM-CNPPJ 40-49 years, male 21.9
GTEX-1N2DW-2826-SM-E9TK5 50-59 years, male 21.9
GTEX-13PVQ-3026-SM-5SI93 50-59 years, male 21.0
GTEX-1HUB1-2926-SM-ACKXA 60-69 years, male 20.8
GTEX-1HB9E-2926-SM-D4P3S 50-59 years, male 20.6
GTEX-13OW8-2826-SM-5L3GC 60-69 years, male 20.4
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Brain - Frontal Cortex (BA9)
Average nTPM: 15.7
Samples: 209

Max nTPM: 55.8
Min nTPM: 7.7
Std nTPM: 4.6
Median nTPM: 15.1
GTEX-X4XY-0011-R10B-SM-46MWS 60-69 years, male 55.8
GTEX-ZE7O-0011-R10a-SM-57WAZ 50-59 years, female 39.3
GTEX-1IL2V-0011-R10a-SM-CL55A 70-79 years, male 37.9
GTEX-11TTK-0011-R10b-SM-DO925 60-69 years, female 31.9
GTEX-13QJC-0011-R10a-SM-5SI63 60-69 years, female 25.0
GTEX-13NYS-0011-R10a-SM-5MR4S 60-69 years, male 22.7
GTEX-13IVO-0011-R10a-SM-5LZY3 70-79 years, male 22.4
GTEX-ZDXO-0011-R10a-SM-4WWD8 60-69 years, male 22.1
GTEX-13JVG-0011-R10b-SM-5KM2P 60-69 years, male 21.7
GTEX-145MI-0011-R10a-SM-5PNZD 60-69 years, female 21.3
GTEX-XMD1-0011-R10A-SM-4AT4A 60-69 years, male 21.0
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CEREBRAL CORTEX - FANTOM5 CAGEi
Max Scaled Tags Per Million 22.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Occipital cortex
Scaled Tags Per Million: 22.6
FF:10163-103B1 76 years, female 22.6
Postcentral gyrus
Scaled Tags Per Million: 17.1
FF:10032-101E5 44-52 years, mixed 17.1
Frontal lobe
Scaled Tags Per Million: 14.4
FF:10040-101F4 32-61 years, mixed 14.4
Insula
Scaled Tags Per Million: 14.7
FF:10039-101F3 20-68 years, mixed 14.7
Medial frontal gyrus
Scaled Tags Per Million: 17.8
FF:10150-102I6 76 years, female 17.8
Medial temporal gyrus
Scaled Tags Per Million: 16.1
FF:10156-103A3 76 years, female 21.1
FF:10183-103D3 60 years, female 11.1
Occipital lobe
Scaled Tags Per Million: 20.4
FF:10076-102A4 27 years, male 20.4
Occipital pole
Scaled Tags Per Million: 15.2
FF:10036-101E9 22-68 years, mixed 15.2
Paracentral gyrus
Scaled Tags Per Million: 15.6
FF:10035-101E8 22-69 years, mixed 15.6
Parietal lobe
Scaled Tags Per Million: 15.9
FF:10157-103A4 76 years, female 18.2
FF:10034-101E7 35-89 years, mixed 18.1
FF:10171-103B9 60 years, female 11.3
Temporal lobe
Scaled Tags Per Million: 20.0
FF:10031-101E4 32-61 years, mixed 20.0

CEREBRAL CORTEX - Pig RNA-seqi
Average nTPM 40.4
Pig sample Sample description nTPM
Occipital cortex
nTPM: 37.6
Samples: 4

Max nTPM: 42.0
Min nTPM: 35.1
Sample A Female 37.0
Sample B Female 36.3
Sample C Male 42.0
Sample D Male 35.1
Retrosplenial cortex
nTPM: 31.2
Samples: 4

Max nTPM: 35.0
Min nTPM: 26.9
Sample A Female 34.5
Sample B Female 26.9
Sample C Male 35.0
Sample D Male 28.2
Cingulate cortex
nTPM: 30.4
Samples: 4

Max nTPM: 37.2
Min nTPM: 24.4
Sample A Female 37.2
Sample B Female 24.4
Sample C Male 33.3
Sample D Male 26.8
Insular cortex
nTPM: 32.4
Samples: 4

Max nTPM: 38.0
Min nTPM: 26.5
Sample A Female 38.0
Sample B Female 26.5
Sample C Male 33.6
Sample D Male 31.4
Motor cortex
nTPM: 35.8
Samples: 4

Max nTPM: 40.2
Min nTPM: 31.9
Sample A Female 36.8
Sample B Female 34.2
Sample C Male 40.2
Sample D Male 31.9
Prefrontal cortex
nTPM: 35.0
Samples: 4

Max nTPM: 42.4
Min nTPM: 30.2
Sample A Female 42.4
Sample B Female 35.2
Sample C Male 30.2
Sample D Male 32.3
Somatosensory cortex
nTPM: 40.4
Samples: 3

Max nTPM: 44.9
Min nTPM: 33.7
Sample B Female 33.7
Sample C Male 42.5
Sample D Male 44.9
Temporal cortex
nTPM: 34.8
Samples: 4

Max nTPM: 38.5
Min nTPM: 32.5
Sample A Female 32.5
Sample B Female 35.8
Sample C Male 38.5
Sample D Male 32.5

CEREBRAL CORTEX - Mouse RNA-seqi
Average nTPM 44.4
Mouse sample Sample description nTPM
Occipital cortex
nTPM: 38.8
Samples: 4

Max nTPM: 45.4
Min nTPM: 32.6
Sample A Male 36.7
Sample B Male 32.6
Sample C Female 45.4
Sample D Female 40.6
Frontal cortex
nTPM: 40.8
Samples: 4

Max nTPM: 50.5
Min nTPM: 30.7
Sample A Male 30.7
Sample B Male 38.0
Sample C Female 44.1
Sample D Female 50.5
Retrosplenial and cingulate cortex
nTPM: 44.5
Samples: 4

Max nTPM: 49.2
Min nTPM: 40.1
Sample A Male 40.1
Sample B Male 44.3
Sample C Female 49.2
Sample D Female 44.2
Somatosensory cortex
nTPM: 37.1
Samples: 4

Max nTPM: 43.2
Min nTPM: 34.5
Sample A Male 34.5
Sample B Male 35.7
Sample C Female 43.2
Sample D Female 34.9

CEREBRAL CORTEX - Allen Mouse ISHi
Max Expression energy 18.8
Allen experiment id Experiment description Expression energy
Cerebral cortex
Expression energy: 18.8
69837493 Antisense, RP_050217_02_B04, Mouse strain C57BL/6J (56 days, male) 18.8

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