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The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
Annotated protein expressioni
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
HPA045044
Normal tissues showed weak to moderate nuclear and cytoplasmic staining. Hematopoietic cells displayed strong cytoplasmic positivity. Hepatocytes, cells in glomeruli and smooth muscle were negative.
HPA046411
A subset of cells in oral mucosa displayed strong cytoplasmic staining. Cells in CNS, esophagus, stomach, rectum, keratinocytes and cells in seminiferus ducts were moderately positive. Remaining normal tissues were weakly stained or negative.
HPA047447
Most of the normal tissues displayed moderate nuclear and cytoplasmic positivity. The lung, liver, breast, seminiferus ducts, cells in CNS, spleen and soft tissues were negative.
HPA058050
Strong cytoplasmic positivity was displayed in intestinal glands along with subset of cells in seminiferous ducts of testis and umbrella cells of urinary bladder. Hepatocytes, renal tubules and myocytes were moderately stained. Decidual cells and gall bladder showed additional membranous staining. Remaining normal tissues were weakly stained or negative.
The Human Protein Atlas project is funded
